4AFHA

Capitella teleta achbp in complex with lobeline
Total Genus 47
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
47
sequence length
213
structure length
213
Chain Sequence
SNGLMAKRLRRELLNTYEQLGKSGLPFLDDIGKVDVKFGLSLQLLKSIEQRGMGFNSIGTFKAIVKLSWVDTILRWDPEPPFDFQKIEISPDEIWTPDIKLFNSVDLDMTLDRTTQAIVFSNGTVLWIPPAVLKVLCVSQDDVDSCHFQFGSWVYSVDEVDIHFMDDKAEVLLDFYQDSLEILENSAQRQEVVYPCCESAYVEMKYLLALRSE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Molecular Actions of Smoking Cessation Drugs at Alpha4Beta2 Nicotinic Receptors Defined in Crystal Structures of a Homologous Binding Protein.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Capitella teleta
molecule keywords ACHBP
total genus 47
structure length 213
sequence length 213
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2012-01-19

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4afhA00
4PIRA 3ZDGA 3WIPA 5AFHA 4NZBA 2ZJVA 2XZ6A 4TWDA 2BYNA 4QH5A 4X5TA 4XK9A 2WNLA 3SH1A 2XQ5A 2WN9A 3LSVA 2YKSA 4AFGA 4ZK1A 4UY2A 3SQ9A 3UU8A 4HFDA 3TLWA 5LXBA 2XQ9A 5CFBA 3UU5A 5AFMA 2BYQA 3ZDHA 4COFA 2BG9B 2XNTA 2YOEA 4IREA 5AINA 2XQ8A 4QH1A 4TWFA 5HCJA 3RHWA 3TLUA 3IGQA 2XQ3A 2XQ7A 4TNVA 3RQWA 5JMEA 2XQAA 4FRRA 2XYSA 2Y54A 5AFKA 3PEOA 4DBMA 3EAMA 2XYTA 2W8FA 2BR8A 3RIAA 3WTKA 5BRXA 5HEOA 5BW2A 4ILCA 4WV9A 4HFIA 4ZR6A 4EZ1A 2W8GA 3WTOA 4QACA 4ZZCA 4QABA 2BG9A 2UZ6A 3JAEA 3UQ7A 3C84A 4D01A 3U8KA 3TLTA 5AFLA 3U8NA 2X00A 2YMDA 4ZJTA 5L4HA 4ALXA 5FJVA 5AFJA 2C9TA 4TWHA 2ZJUA 3GUAA 4LMJA 5J5GA 5AFNA 5HCMA 2X00D 5HEUA 4Z90A 2BYRA 3SQ6A 5IUXA 2WZYA 4UXUA 2XQ6A 4IL9A 5SYOA 4F8HA 3WTIA 2WNCA 3T4MA 4A98A 3JADA 2QC1B 4ILAA 3ZKRA 4ZJSA 4QH4A 3C79A 5TVCA 4XHEA 4ZZBA 5J5FA 4ZK4A 5KE4A 3U8MA 4UM3P 4LMLA 3WTNA 5CO5A 5LG3A 2YMEA 3UU4A 3U8JA 3U8LA 2VL0A 2BR7A 4HFHA 4UM1A 3SIOA 4BFQA 3WTLA 5BP0A 3JAFA 3P4WA 1UX2A 2PH9A 3RIFA 2BJ0A 5AFMB 1UV6A 3EI0A 2WNJA 2Y56A 4HFBA 4B5DA 2XNUA 3TLVA 4Z91A 3UU3A 3UU6A 5J5HA 4HFCA 4LMKA 4ZRUA 3RQUA 4HQPA 4A97A 2Y7YA 5L47A 5J5IA 2BG9C 2XQ4A 4NPPA 2BG9E 3EHZA 4UM3S 5L4EA 3UUBA 2XZ5A 4ILBA 3UQ4A 2BYPA 3RI5A 5J0ZA 4UM3A 3TLSA 2Y58A 4IL4A 2YN6A 2Y57A 3WTHA 5KZUA 4TNWA 5HEGA 3P50A 4BQTA 4QAAA 3WTJA 3PMZA 1I9BA 4HFEA 5HEHA 3WTMA 4AFTA 2PGZA 4AFHA 1UW6A 2BYSA 5HEJA 2XNVA
chains in the Genus database with same CATH superfamily
4PIRA 3ZDGA 3WIPA 5AFHA 4NZBA 2ZJVA 2XZ6A 4TWDA 2BYNA 4QH5A 4X5TA 4XK9A 2WNLA 3SH1A 2XQ5A 2WN9A 3LSVA 2YKSA 4AFGA 4ZK1A 4UY2A 3SQ9A 3UU8A 4HFDA 3TLWA 5LXBA 2XQ9A 5CFBA 3UU5A 5AFMA 2BYQA 3ZDHA 4COFA 2BG9B 2XNTA 2YOEA 4IREA 5AINA 2XQ8A 4QH1A 4TWFA 5HCJA 3RHWA 3TLUA 3IGQA 2XQ3A 2XQ7A 4TNVA 3RQWA 5JMEA 2XQAA 4FRRA 2XYSA 2Y54A 5AFKA 3PEOA 4DBMA 3EAMA 2XYTA 2W8FA 2BR8A 3RIAA 3WTKA 5BRXA 5HEOA 5BW2A 4ILCA 4WV9A 4HFIA 4ZR6A 4EZ1A 2W8GA 3WTOA 4QACA 4ZZCA 4QABA 2BG9A 2UZ6A 3JAEA 3UQ7A 3C84A 4D01A 3U8KA 3TLTA 5AFLA 3U8NA 2X00A 2YMDA 4ZJTA 5L4HA 4ALXA 5FJVA 5AFJA 2C9TA 4TWHA 2ZJUA 3GUAA 4LMJA 5J5GA 5AFNA 5HCMA 2X00D 5HEUA 4Z90A 2BYRA 3SQ6A 5IUXA 2WZYA 4UXUA 2XQ6A 4IL9A 5SYOA 4F8HA 3WTIA 2WNCA 3T4MA 4A98A 3JADA 2QC1B 4ILAA 3ZKRA 4ZJSA 4QH4A 3C79A 5TVCA 4XHEA 4ZZBA 5J5FA 4ZK4A 5KE4A 3U8MA 4UM3P 4LMLA 3WTNA 5CO5A 5LG3A 2YMEA 3UU4A 3U8JA 3U8LA 2VL0A 2BR7A 4HFHA 4UM1A 3SIOA 4BFQA 3WTLA 5BP0A 3JAFA 3P4WA 1UX2A 2PH9A 3RIFA 2BJ0A 5AFMB 1UV6A 3EI0A 2WNJA 2Y56A 4HFBA 4B5DA 2XNUA 3TLVA 4Z91A 3UU3A 3UU6A 5J5HA 4HFCA 4LMKA 4ZRUA 3RQUA 4HQPA 4A97A 2Y7YA 5L47A 5J5IA 2BG9C 2XQ4A 4NPPA 2BG9E 3EHZA 4UM3S 5L4EA 3UUBA 2XZ5A 4ILBA 3UQ4A 2BYPA 3RI5A 5J0ZA 4UM3A 3TLSA 2Y58A 4IL4A 2YN6A 2Y57A 3WTHA 5KZUA 4TNWA 5HEGA 3P50A 4BQTA 4QAAA 3WTJA 3PMZA 1I9BA 4HFEA 5HEHA 3WTMA 4AFTA 2PGZA 4AFHA 1UW6A 2BYSA 5HEJA 2XNVA
chains in the Genus database with same CATH topology
4PIRA 3ZDGA 3WIPA 5AFHA 4NZBA 2ZJVA 2XZ6A 4TWDA 2BYNA 4QH5A 4X5TA 4XK9A 2WNLA 3SH1A 2XQ5A 2WN9A 3LSVA 2YKSA 4AFGA 4ZK1A 4UY2A 3SQ9A 3UU8A 4HFDA 3TLWA 5LXBA 2XQ9A 5CFBA 3UU5A 5AFMA 2BYQA 3ZDHA 4COFA 2BG9B 2XNTA 2YOEA 4IREA 5AINA 2XQ8A 4QH1A 4TWFA 5HCJA 3RHWA 3TLUA 3IGQA 2XQ3A 2XQ7A 4TNVA 3RQWA 5JMEA 2XQAA 4FRRA 2XYSA 2Y54A 5AFKA 3PEOA 4DBMA 3EAMA 2XYTA 2W8FA 2BR8A 3RIAA 3WTKA 5BRXA 5HEOA 5BW2A 4ILCA 4WV9A 4HFIA 4ZR6A 4EZ1A 2W8GA 3WTOA 4QACA 4ZZCA 4QABA 2BG9A 2UZ6A 3JAEA 3UQ7A 3C84A 4D01A 3U8KA 3TLTA 5AFLA 3U8NA 2X00A 2YMDA 4ZJTA 5L4HA 4ALXA 5FJVA 5AFJA 2C9TA 4TWHA 2ZJUA 3GUAA 4LMJA 5J5GA 5AFNA 5HCMA 2X00D 5HEUA 4Z90A 2BYRA 3SQ6A 5IUXA 2WZYA 4UXUA 2XQ6A 4IL9A 5SYOA 4F8HA 3WTIA 2WNCA 3T4MA 4A98A 3JADA 2QC1B 4ILAA 3ZKRA 4ZJSA 4QH4A 3C79A 5TVCA 4XHEA 4ZZBA 5J5FA 4ZK4A 5KE4A 3U8MA 4UM3P 4LMLA 3WTNA 5CO5A 5LG3A 2YMEA 3UU4A 3U8JA 3U8LA 2VL0A 2BR7A 4HFHA 4UM1A 3SIOA 4BFQA 3WTLA 5BP0A 3JAFA 3P4WA 1UX2A 2PH9A 3RIFA 2BJ0A 5AFMB 1UV6A 3EI0A 2WNJA 2Y56A 4HFBA 4B5DA 2XNUA 3TLVA 4Z91A 3UU3A 3UU6A 5J5HA 4HFCA 4LMKA 4ZRUA 3RQUA 4HQPA 4A97A 2Y7YA 5L47A 5J5IA 2BG9C 2XQ4A 4NPPA 2BG9E 3EHZA 4UM3S 5L4EA 3UUBA 2XZ5A 4ILBA 3UQ4A 2BYPA 3RI5A 5J0ZA 4UM3A 3TLSA 2Y58A 4IL4A 2YN6A 2Y57A 3WTHA 5KZUA 4TNWA 5HEGA 3P50A 4BQTA 4QAAA 3WTJA 3PMZA 1I9BA 4HFEA 5HEHA 3WTMA 4AFTA 2PGZA 4AFHA 1UW6A 2BYSA 5HEJA 2XNVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PIR A;  3ZDG A;  3WIP A;  5AFH A;  4NZB A;  2ZJV A;  2XZ6 A;  4TWD A;  2BYN A;  4QH5 A;  4X5T A;  4XK9 A;  2WNL A;  3SH1 A;  2XQ5 A;  2WN9 A;  3LSV A;  2YKS A;  4AFG A;  4ZK1 A;  4UY2 A;  3SQ9 A;  3UU8 A;  4HFD A;  3TLW A;  5LXB A;  2XQ9 A;  5CFB A;  3UU5 A;  5AFM A;  2BYQ A;  3ZDH A;  4COF A;  2BG9 B;  2XNT A;  2YOE A;  4IRE A;  5AIN A;  2XQ8 A;  4QH1 A;  4TWF A;  5HCJ A;  3RHW A;  3TLU A;  3IGQ A;  2XQ3 A;  2XQ7 A;  4TNV A;  3RQW A;  5JME A;  2XQA A;  4FRR A;  2XYS A;  2Y54 A;  5AFK A;  3PEO A;  4DBM A;  3EAM A;  2XYT A;  2W8F A;  2BR8 A;  3RIA A;  3WTK A;  5BRX A;  5HEO A;  5BW2 A;  4ILC A;  4WV9 A;  4HFI A;  4ZR6 A;  4EZ1 A;  2W8G A;  3WTO A;  4QAC A;  4ZZC A;  4QAB A;  2BG9 A;  2UZ6 A;  3JAE A;  3UQ7 A;  3C84 A;  4D01 A;  3U8K A;  3TLT A;  5AFL A;  3U8N A;  2X00 A;  2YMD A;  4ZJT A;  5L4H A;  4ALX A;  5FJV A;  5AFJ A;  2C9T A;  4TWH A;  2ZJU A;  3GUA A;  4LMJ A;  5J5G A;  5AFN A;  5HCM A;  2X00 D;  5HEU A;  4Z90 A;  2BYR A;  3SQ6 A;  5IUX A;  2WZY A;  4UXU A;  2XQ6 A;  4IL9 A;  5SYO A;  4F8H A;  3WTI A;  2WNC A;  3T4M A;  4A98 A;  3JAD A;  2QC1 B;  4ILA A;  3ZKR A;  4ZJS A;  4QH4 A;  3C79 A;  5TVC A;  4XHE A;  4ZZB A;  5J5F A;  4ZK4 A;  5KE4 A;  3U8M A;  4UM3 P;  4LML A;  3WTN A;  5CO5 A;  5LG3 A;  2YME A;  3UU4 A;  3U8J A;  3U8L A;  2VL0 A;  2BR7 A;  4HFH A;  4UM1 A;  3SIO A;  4BFQ A;  3WTL A;  5BP0 A;  3JAF A;  3P4W A;  1UX2 A;  2PH9 A;  3RIF A;  2BJ0 A;  5AFM B;  1UV6 A;  3EI0 A;  2WNJ A;  2Y56 A;  4HFB A;  4B5D A;  2XNU A;  3TLV A;  4Z91 A;  3UU3 A;  3UU6 A;  5J5H A;  4HFC A;  4LMK A;  4ZRU A;  3RQU A;  4HQP A;  4A97 A;  2Y7Y A;  5L47 A;  5J5I A;  2BG9 C;  2XQ4 A;  4NPP A;  2BG9 E;  3EHZ A;  4UM3 S;  5L4E A;  3UUB A;  2XZ5 A;  4ILB A;  3UQ4 A;  2BYP A;  3RI5 A;  5J0Z A;  4UM3 A;  3TLS A;  2Y58 A;  4IL4 A;  2YN6 A;  2Y57 A;  3WTH A;  5KZU A;  4TNW A;  5HEG A;  3P50 A;  4BQT A;  4QAA A;  3WTJ A;  3PMZ A;  1I9B A;  4HFE A;  5HEH A;  3WTM A;  4AFT A;  2PGZ A;  4AFH A;  1UW6 A;  2BYS A;  5HEJ A;  2XNV A; 
#chains in the Genus database with same CATH topology
 4PIR A;  3ZDG A;  3WIP A;  5AFH A;  4NZB A;  2ZJV A;  2XZ6 A;  4TWD A;  2BYN A;  4QH5 A;  4X5T A;  4XK9 A;  2WNL A;  3SH1 A;  2XQ5 A;  2WN9 A;  3LSV A;  2YKS A;  4AFG A;  4ZK1 A;  4UY2 A;  3SQ9 A;  3UU8 A;  4HFD A;  3TLW A;  5LXB A;  2XQ9 A;  5CFB A;  3UU5 A;  5AFM A;  2BYQ A;  3ZDH A;  4COF A;  2BG9 B;  2XNT A;  2YOE A;  4IRE A;  5AIN A;  2XQ8 A;  4QH1 A;  4TWF A;  5HCJ A;  3RHW A;  3TLU A;  3IGQ A;  2XQ3 A;  2XQ7 A;  4TNV A;  3RQW A;  5JME A;  2XQA A;  4FRR A;  2XYS A;  2Y54 A;  5AFK A;  3PEO A;  4DBM A;  3EAM A;  2XYT A;  2W8F A;  2BR8 A;  3RIA A;  3WTK A;  5BRX A;  5HEO A;  5BW2 A;  4ILC A;  4WV9 A;  4HFI A;  4ZR6 A;  4EZ1 A;  2W8G A;  3WTO A;  4QAC A;  4ZZC A;  4QAB A;  2BG9 A;  2UZ6 A;  3JAE A;  3UQ7 A;  3C84 A;  4D01 A;  3U8K A;  3TLT A;  5AFL A;  3U8N A;  2X00 A;  2YMD A;  4ZJT A;  5L4H A;  4ALX A;  5FJV A;  5AFJ A;  2C9T A;  4TWH A;  2ZJU A;  3GUA A;  4LMJ A;  5J5G A;  5AFN A;  5HCM A;  2X00 D;  5HEU A;  4Z90 A;  2BYR A;  3SQ6 A;  5IUX A;  2WZY A;  4UXU A;  2XQ6 A;  4IL9 A;  5SYO A;  4F8H A;  3WTI A;  2WNC A;  3T4M A;  4A98 A;  3JAD A;  2QC1 B;  4ILA A;  3ZKR A;  4ZJS A;  4QH4 A;  3C79 A;  5TVC A;  4XHE A;  4ZZB A;  5J5F A;  4ZK4 A;  5KE4 A;  3U8M A;  4UM3 P;  4LML A;  3WTN A;  5CO5 A;  5LG3 A;  2YME A;  3UU4 A;  3U8J A;  3U8L A;  2VL0 A;  2BR7 A;  4HFH A;  4UM1 A;  3SIO A;  4BFQ A;  3WTL A;  5BP0 A;  3JAF A;  3P4W A;  1UX2 A;  2PH9 A;  3RIF A;  2BJ0 A;  5AFM B;  1UV6 A;  3EI0 A;  2WNJ A;  2Y56 A;  4HFB A;  4B5D A;  2XNU A;  3TLV A;  4Z91 A;  3UU3 A;  3UU6 A;  5J5H A;  4HFC A;  4LMK A;  4ZRU A;  3RQU A;  4HQP A;  4A97 A;  2Y7Y A;  5L47 A;  5J5I A;  2BG9 C;  2XQ4 A;  4NPP A;  2BG9 E;  3EHZ A;  4UM3 S;  5L4E A;  3UUB A;  2XZ5 A;  4ILB A;  3UQ4 A;  2BYP A;  3RI5 A;  5J0Z A;  4UM3 A;  3TLS A;  2Y58 A;  4IL4 A;  2YN6 A;  2Y57 A;  3WTH A;  5KZU A;  4TNW A;  5HEG A;  3P50 A;  4BQT A;  4QAA A;  3WTJ A;  3PMZ A;  1I9B A;  4HFE A;  5HEH A;  3WTM A;  4AFT A;  2PGZ A;  4AFH A;  1UW6 A;  2BYS A;  5HEJ A;  2XNV A; 
#chains in the Genus database with same CATH homology
 4PIR A;  3ZDG A;  3WIP A;  5AFH A;  4NZB A;  2ZJV A;  2XZ6 A;  4TWD A;  2BYN A;  4QH5 A;  4X5T A;  4XK9 A;  2WNL A;  3SH1 A;  2XQ5 A;  2WN9 A;  3LSV A;  2YKS A;  4AFG A;  4ZK1 A;  4UY2 A;  3SQ9 A;  3UU8 A;  4HFD A;  3TLW A;  5LXB A;  2XQ9 A;  5CFB A;  3UU5 A;  5AFM A;  2BYQ A;  3ZDH A;  4COF A;  2BG9 B;  2XNT A;  2YOE A;  4IRE A;  5AIN A;  2XQ8 A;  4QH1 A;  4TWF A;  5HCJ A;  3RHW A;  3TLU A;  3IGQ A;  2XQ3 A;  2XQ7 A;  4TNV A;  3RQW A;  5JME A;  2XQA A;  4FRR A;  2XYS A;  2Y54 A;  5AFK A;  3PEO A;  4DBM A;  3EAM A;  2XYT A;  2W8F A;  2BR8 A;  3RIA A;  3WTK A;  5BRX A;  5HEO A;  5BW2 A;  4ILC A;  4WV9 A;  4HFI A;  4ZR6 A;  4EZ1 A;  2W8G A;  3WTO A;  4QAC A;  4ZZC A;  4QAB A;  2BG9 A;  2UZ6 A;  3JAE A;  3UQ7 A;  3C84 A;  4D01 A;  3U8K A;  3TLT A;  5AFL A;  3U8N A;  2X00 A;  2YMD A;  4ZJT A;  5L4H A;  4ALX A;  5FJV A;  5AFJ A;  2C9T A;  4TWH A;  2ZJU A;  3GUA A;  4LMJ A;  5J5G A;  5AFN A;  5HCM A;  2X00 D;  5HEU A;  4Z90 A;  2BYR A;  3SQ6 A;  5IUX A;  2WZY A;  4UXU A;  2XQ6 A;  4IL9 A;  5SYO A;  4F8H A;  3WTI A;  2WNC A;  3T4M A;  4A98 A;  3JAD A;  2QC1 B;  4ILA A;  3ZKR A;  4ZJS A;  4QH4 A;  3C79 A;  5TVC A;  4XHE A;  4ZZB A;  5J5F A;  4ZK4 A;  5KE4 A;  3U8M A;  4UM3 P;  4LML A;  3WTN A;  5CO5 A;  5LG3 A;  2YME A;  3UU4 A;  3U8J A;  3U8L A;  2VL0 A;  2BR7 A;  4HFH A;  4UM1 A;  3SIO A;  4BFQ A;  3WTL A;  5BP0 A;  3JAF A;  3P4W A;  1UX2 A;  2PH9 A;  3RIF A;  2BJ0 A;  5AFM B;  1UV6 A;  3EI0 A;  2WNJ A;  2Y56 A;  4HFB A;  4B5D A;  2XNU A;  3TLV A;  4Z91 A;  3UU3 A;  3UU6 A;  5J5H A;  4HFC A;  4LMK A;  4ZRU A;  3RQU A;  4HQP A;  4A97 A;  2Y7Y A;  5L47 A;  5J5I A;  2BG9 C;  2XQ4 A;  4NPP A;  2BG9 E;  3EHZ A;  4UM3 S;  5L4E A;  3UUB A;  2XZ5 A;  4ILB A;  3UQ4 A;  2BYP A;  3RI5 A;  5J0Z A;  4UM3 A;  3TLS A;  2Y58 A;  4IL4 A;  2YN6 A;  2Y57 A;  3WTH A;  5KZU A;  4TNW A;  5HEG A;  3P50 A;  4BQT A;  4QAA A;  3WTJ A;  3PMZ A;  1I9B A;  4HFE A;  5HEH A;  3WTM A;  4AFT A;  2PGZ A;  4AFH A;  1UW6 A;  2BYS A;  5HEJ A;  2XNV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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