4ALX | Genus

Total Genus 52

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	52
sequence length	210
structure length	210
Chain Sequence	LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTENSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Acetylcholine-binding protein
source organism	Lymnaea stagnalis
publication title	Crystal Structure of Lymnaea Stagnalis Achbp Complexed with the Potent Nachr Antagonist Dh-Betab-E Suggests a Unique Mode of Antagonism pubmed doi rcsb
molecule keywords	ACETYLCHOLINE BINDING PROTEIN
total genus	52
structure length	210
sequence length	210
chains with identical sequence	B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date	2012-03-06

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	4alxA00

4XHEA 2X00A 2WZYA 3UU3A 2BR8A 3TLVA 2Y57A 3TLUA 2UZ6A 3RIFA 4AFHA 3UU6A 3WTNA 2XYTA 3RI5A 4F8HA 4LMKA 2XZ6A 2XQ6A 2YOEA 3JADA 2XYSA 2Y7YA 3P50A 3EI0A 4NZBA 4QACA 3ZDHA 3U8NA 4ZJTA 2YMEA 5HCMA 5BRXA 5HEJA 5J5FA 1UX2A 4TNVA 4ZRUA 2BYQA 3ZKRA 5HCJA 5AFMA 2XQ7A 2XQ9A 2XQ3A 2Y54A 2ZJVA 3EAMA 3WIPA 5L4EA 3PEOA 4TNWA 4HFHA 2XNVA 4AFTA 2X00D 2BYPA 3P4WA 2BR7A 5FJVA 5AFMB 4IREA 2BG9C 5HEHA 3UUBA 2BG9B 2WNLA 2YN6A 4HFIA 5AFLA 5IUXA 2XZ5A 3WTLA 4QH4A 3RQUA 4COFA 4Z91A 3WTIA 5TVCA 3TLTA 5LXBA 2Y58A 3ZDGA 4UM3A 4UM3S 2BYSA 4WV9A 4XK9A 3TLSA 4D01A 3SH1A 2WNCA 5SYOA 3U8KA 4ZK1A 2VL0A 5JMEA 5BW2A 5AINA 5J5IA 4TWHA 2BG9A 5L47A 3SQ6A 4DBMA 2XQ8A 3C79A 5LG3A 4NPPA 3EHZA 3WTJA 4TWFA 4HFBA 5HEUA 3WTMA 5HEGA 4HFCA 4BQTA 4ILBA 5CO5A 4HFDA 5AFHA 3U8LA 1UV6A 4QH1A 2BG9E 2XNTA 2Y56A 2WNJA 4TWDA 4ZR6A 4ZK4A 2XQ5A 3JAEA 4UM1A 5AFNA 5KE4A 4IL9A 3UU4A 2BYNA 3IGQA 2W8FA 3WTOA 3JAFA 3U8JA 3WTHA 4LMJA 3UQ4A 3RHWA 4EZ1A 4ZJSA 3SQ9A 5BP0A 2W8GA 1UW6A 5J5GA 2YMDA 4LMLA 1I9BA 4HQPA 3C84A 4ALXA 4X5TA 3LSVA 4FRRA 4ILAA 4BFQA 4A98A 2PH9A 4IL4A 4ILCA 4QAAA 4ZZCA 5AFKA 2QC1B 4PIRA 3TLWA 5HEOA 4Z90A 5L4HA 2XQAA 3RQWA 3UQ7A 3GUAA 4B5DA 4QABA 3UU5A 2XQ4A 4A97A 2WN9A 3U8MA 5J5HA 2ZJUA 3T4MA 3RIAA 2BJ0A 4UY2A 4AFGA 5AFJA 2BYRA 2XNUA 3WTKA 4UXUA 5CFBA 2PGZA 4HFEA 5KZUA 3UU8A 2YKSA 3PMZA 4QH5A 4UM3P 4ZZBA 5J0ZA 2C9TA 3SIOA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4XHE A;  2X00 A;  2WZY A;  3UU3 A;  2BR8 A;  3TLV A;  2Y57 A;  3TLU A;  2UZ6 A;  3RIF A;  4AFH A;  3UU6 A;  3WTN A;  2XYT A;  3RI5 A;  4F8H A;  4LMK A;  2XZ6 A;  2XQ6 A;  2YOE A;  3JAD A;  2XYS A;  2Y7Y A;  3P50 A;  3EI0 A;  4NZB A;  4QAC A;  3ZDH A;  3U8N A;  4ZJT A;  2YME A;  5HCM A;  5BRX A;  5HEJ A;  5J5F A;  1UX2 A;  4TNV A;  4ZRU A;  2BYQ A;  3ZKR A;  5HCJ A;  5AFM A;  2XQ7 A;  2XQ9 A;  2XQ3 A;  2Y54 A;  2ZJV A;  3EAM A;  3WIP A;  5L4E A;  3PEO A;  4TNW A;  4HFH A;  2XNV A;  4AFT A;  2X00 D;  2BYP A;  3P4W A;  2BR7 A;  5FJV A;  5AFM B;  4IRE A;  2BG9 C;  5HEH A;  3UUB A;  2BG9 B;  2WNL A;  2YN6 A;  4HFI A;  5AFL A;  5IUX A;  2XZ5 A;  3WTL A;  4QH4 A;  3RQU A;  4COF A;  4Z91 A;  3WTI A;  5TVC A;  3TLT A;  5LXB A;  2Y58 A;  3ZDG A;  4UM3 A;  4UM3 S;  2BYS A;  4WV9 A;  4XK9 A;  3TLS A;  4D01 A;  3SH1 A;  2WNC A;  5SYO A;  3U8K A;  4ZK1 A;  2VL0 A;  5JME A;  5BW2 A;  5AIN A;  5J5I A;  4TWH A;  2BG9 A;  5L47 A;  3SQ6 A;  4DBM A;  2XQ8 A;  3C79 A;  5LG3 A;  4NPP A;  3EHZ A;  3WTJ A;  4TWF A;  4HFB A;  5HEU A;  3WTM A;  5HEG A;  4HFC A;  4BQT A;  4ILB A;  5CO5 A;  4HFD A;  5AFH A;  3U8L A;  1UV6 A;  4QH1 A;  2BG9 E;  2XNT A;  2Y56 A;  2WNJ A;  4TWD A;  4ZR6 A;  4ZK4 A;  2XQ5 A;  3JAE A;  4UM1 A;  5AFN A;  5KE4 A;  4IL9 A;  3UU4 A;  2BYN A;  3IGQ A;  2W8F A;  3WTO A;  3JAF A;  3U8J A;  3WTH A;  4LMJ A;  3UQ4 A;  3RHW A;  4EZ1 A;  4ZJS A;  3SQ9 A;  5BP0 A;  2W8G A;  1UW6 A;  5J5G A;  2YMD A;  4LML A;  1I9B A;  4HQP A;  3C84 A;  4ALX A;  4X5T A;  3LSV A;  4FRR A;  4ILA A;  4BFQ A;  4A98 A;  2PH9 A;  4IL4 A;  4ILC A;  4QAA A;  4ZZC A;  5AFK A;  2QC1 B;  4PIR A;  3TLW A;  5HEO A;  4Z90 A;  5L4H A;  2XQA A;  3RQW A;  3UQ7 A;  3GUA A;  4B5D A;  4QAB A;  3UU5 A;  2XQ4 A;  4A97 A;  2WN9 A;  3U8M A;  5J5H A;  2ZJU A;  3T4M A;  3RIA A;  2BJ0 A;  4UY2 A;  4AFG A;  5AFJ A;  2BYR A;  2XNU A;  3WTK A;  4UXU A;  5CFB A;  2PGZ A;  4HFE A;  5KZU A;  3UU8 A;  2YKS A;  3PMZ A;  4QH5 A;  4UM3 P;  4ZZB A;  5J0Z A;  2C9T A;  3SIO A; 
#chains in the Genus database with same CATH topology
 4XHE A;  2X00 A;  2WZY A;  3UU3 A;  2BR8 A;  3TLV A;  2Y57 A;  3TLU A;  2UZ6 A;  3RIF A;  4AFH A;  3UU6 A;  3WTN A;  2XYT A;  3RI5 A;  4F8H A;  4LMK A;  2XZ6 A;  2XQ6 A;  2YOE A;  3JAD A;  2XYS A;  2Y7Y A;  3P50 A;  3EI0 A;  4NZB A;  4QAC A;  3ZDH A;  3U8N A;  4ZJT A;  2YME A;  5HCM A;  5BRX A;  5HEJ A;  5J5F A;  1UX2 A;  4TNV A;  4ZRU A;  2BYQ A;  3ZKR A;  5HCJ A;  5AFM A;  2XQ7 A;  2XQ9 A;  2XQ3 A;  2Y54 A;  2ZJV A;  3EAM A;  3WIP A;  5L4E A;  3PEO A;  4TNW A;  4HFH A;  2XNV A;  4AFT A;  2X00 D;  2BYP A;  3P4W A;  2BR7 A;  5FJV A;  5AFM B;  4IRE A;  2BG9 C;  5HEH A;  3UUB A;  2BG9 B;  2WNL A;  2YN6 A;  4HFI A;  5AFL A;  5IUX A;  2XZ5 A;  3WTL A;  4QH4 A;  3RQU A;  4COF A;  4Z91 A;  3WTI A;  5TVC A;  3TLT A;  5LXB A;  2Y58 A;  3ZDG A;  4UM3 A;  4UM3 S;  2BYS A;  4WV9 A;  4XK9 A;  3TLS A;  4D01 A;  3SH1 A;  2WNC A;  5SYO A;  3U8K A;  4ZK1 A;  2VL0 A;  5JME A;  5BW2 A;  5AIN A;  5J5I A;  4TWH A;  2BG9 A;  5L47 A;  3SQ6 A;  4DBM A;  2XQ8 A;  3C79 A;  5LG3 A;  4NPP A;  3EHZ A;  3WTJ A;  4TWF A;  4HFB A;  5HEU A;  3WTM A;  5HEG A;  4HFC A;  4BQT A;  4ILB A;  5CO5 A;  4HFD A;  5AFH A;  3U8L A;  1UV6 A;  4QH1 A;  2BG9 E;  2XNT A;  2Y56 A;  2WNJ A;  4TWD A;  4ZR6 A;  4ZK4 A;  2XQ5 A;  3JAE A;  4UM1 A;  5AFN A;  5KE4 A;  4IL9 A;  3UU4 A;  2BYN A;  3IGQ A;  2W8F A;  3WTO A;  3JAF A;  3U8J A;  3WTH A;  4LMJ A;  3UQ4 A;  3RHW A;  4EZ1 A;  4ZJS A;  3SQ9 A;  5BP0 A;  2W8G A;  1UW6 A;  5J5G A;  2YMD A;  4LML A;  1I9B A;  4HQP A;  3C84 A;  4ALX A;  4X5T A;  3LSV A;  4FRR A;  4ILA A;  4BFQ A;  4A98 A;  2PH9 A;  4IL4 A;  4ILC A;  4QAA A;  4ZZC A;  5AFK A;  2QC1 B;  4PIR A;  3TLW A;  5HEO A;  4Z90 A;  5L4H A;  2XQA A;  3RQW A;  3UQ7 A;  3GUA A;  4B5D A;  4QAB A;  3UU5 A;  2XQ4 A;  4A97 A;  2WN9 A;  3U8M A;  5J5H A;  2ZJU A;  3T4M A;  3RIA A;  2BJ0 A;  4UY2 A;  4AFG A;  5AFJ A;  2BYR A;  2XNU A;  3WTK A;  4UXU A;  5CFB A;  2PGZ A;  4HFE A;  5KZU A;  3UU8 A;  2YKS A;  3PMZ A;  4QH5 A;  4UM3 P;  4ZZB A;  5J0Z A;  2C9T A;  3SIO A; 
#chains in the Genus database with same CATH homology
 4XHE A;  2X00 A;  2WZY A;  3UU3 A;  2BR8 A;  3TLV A;  2Y57 A;  3TLU A;  2UZ6 A;  3RIF A;  4AFH A;  3UU6 A;  3WTN A;  2XYT A;  3RI5 A;  4F8H A;  4LMK A;  2XZ6 A;  2XQ6 A;  2YOE A;  3JAD A;  2XYS A;  2Y7Y A;  3P50 A;  3EI0 A;  4NZB A;  4QAC A;  3ZDH A;  3U8N A;  4ZJT A;  2YME A;  5HCM A;  5BRX A;  5HEJ A;  5J5F A;  1UX2 A;  4TNV A;  4ZRU A;  2BYQ A;  3ZKR A;  5HCJ A;  5AFM A;  2XQ7 A;  2XQ9 A;  2XQ3 A;  2Y54 A;  2ZJV A;  3EAM A;  3WIP A;  5L4E A;  3PEO A;  4TNW A;  4HFH A;  2XNV A;  4AFT A;  2X00 D;  2BYP A;  3P4W A;  2BR7 A;  5FJV A;  5AFM B;  4IRE A;  2BG9 C;  5HEH A;  3UUB A;  2BG9 B;  2WNL A;  2YN6 A;  4HFI A;  5AFL A;  5IUX A;  2XZ5 A;  3WTL A;  4QH4 A;  3RQU A;  4COF A;  4Z91 A;  3WTI A;  5TVC A;  3TLT A;  5LXB A;  2Y58 A;  3ZDG A;  4UM3 A;  4UM3 S;  2BYS A;  4WV9 A;  4XK9 A;  3TLS A;  4D01 A;  3SH1 A;  2WNC A;  5SYO A;  3U8K A;  4ZK1 A;  2VL0 A;  5JME A;  5BW2 A;  5AIN A;  5J5I A;  4TWH A;  2BG9 A;  5L47 A;  3SQ6 A;  4DBM A;  2XQ8 A;  3C79 A;  5LG3 A;  4NPP A;  3EHZ A;  3WTJ A;  4TWF A;  4HFB A;  5HEU A;  3WTM A;  5HEG A;  4HFC A;  4BQT A;  4ILB A;  5CO5 A;  4HFD A;  5AFH A;  3U8L A;  1UV6 A;  4QH1 A;  2BG9 E;  2XNT A;  2Y56 A;  2WNJ A;  4TWD A;  4ZR6 A;  4ZK4 A;  2XQ5 A;  3JAE A;  4UM1 A;  5AFN A;  5KE4 A;  4IL9 A;  3UU4 A;  2BYN A;  3IGQ A;  2W8F A;  3WTO A;  3JAF A;  3U8J A;  3WTH A;  4LMJ A;  3UQ4 A;  3RHW A;  4EZ1 A;  4ZJS A;  3SQ9 A;  5BP0 A;  2W8G A;  1UW6 A;  5J5G A;  2YMD A;  4LML A;  1I9B A;  4HQP A;  3C84 A;  4ALX A;  4X5T A;  3LSV A;  4FRR A;  4ILA A;  4BFQ A;  4A98 A;  2PH9 A;  4IL4 A;  4ILC A;  4QAA A;  4ZZC A;  5AFK A;  2QC1 B;  4PIR A;  3TLW A;  5HEO A;  4Z90 A;  5L4H A;  2XQA A;  3RQW A;  3UQ7 A;  3GUA A;  4B5D A;  4QAB A;  3UU5 A;  2XQ4 A;  4A97 A;  2WN9 A;  3U8M A;  5J5H A;  2ZJU A;  3T4M A;  3RIA A;  2BJ0 A;  4UY2 A;  4AFG A;  5AFJ A;  2BYR A;  2XNU A;  3WTK A;  4UXU A;  5CFB A;  2PGZ A;  4HFE A;  5KZU A;  3UU8 A;  2YKS A;  3PMZ A;  4QH5 A;  4UM3 P;  4ZZB A;  5J0Z A;  2C9T A;  3SIO A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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4ALXA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations