The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
48
|
sequence length |
206
|
structure length |
206
|
Chain Sequence |
QANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Structural Characterization of Binding Mode of Smoking Cessation Drugs to Nicotinic Acetylcholine Receptors Through Study of Ligand Complexes with Acetylcholine-Binding Protein.
pubmed doi rcsb |
| molecule tags |
Receptor
|
| source organism |
Aplysia californica
|
| molecule keywords |
SOLUBLE ACETYLCHOLINE RECEPTOR
|
| total genus |
48
|
| structure length |
206
|
| sequence length |
206
|
| chains with identical sequence |
B, C, D, E
|
| ec nomenclature | |
| pdb deposition date | 2013-06-02 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Distorted Sandwich | Acetylcholine Binding Protein; Chain: A, | Neurotransmitter-gated ion-channel ligand-binding domain |
#chains in the Genus database with same CATH superfamily 4ILC A; 4PIR A; 2BYN A; 4ZJS A; 1UX2 A; 5TVC A; 2PGZ A; 3UU8 A; 4HFH A; 2YMD A; 5L4H A; 5FJV A; 3WIP A; 3TLT A; 3UUB A; 3IGQ A; 4TNV A; 2YKS A; 2QC1 B; 4HFE A; 4WV9 A; 2W8G A; 2XYT A; 3P50 A; 4QH5 A; 3TLS A; 2UZ6 A; 5AFM B; 3PEO A; 2XZ6 A; 4IL4 A; 2WNL A; 5AFJ A; 4UM3 P; 4TWF A; 3U8M A; 5JME A; 3SH1 A; 4FRR A; 3WTL A; 5LXB A; 4LMK A; 4ZRU A; 5HEG A; 5L47 A; 4LMJ A; 2XQ4 A; 3SIO A; 2C9T A; 2VL0 A; 4NPP A; 2Y54 A; 3T4M A; 4BQT A; 3JAE A; 3TLW A; 2BR7 A; 3WTO A; 2YME A; 2XZ5 A; 4HFD A; 4TWH A; 4ZK4 A; 4B5D A; 5HEJ A; 2BYR A; 3LSV A; 5J5I A; 4BFQ A; 4TWD A; 3EHZ A; 4A98 A; 2WNJ A; 4UY2 A; 2YOE A; 2XQ5 A; 2X00 A; 5AIN A; 5BRX A; 1UV6 A; 5BP0 A; 3JAF A; 4F8H A; 4COF A; 2XQ9 A; 3EI0 A; 3U8K A; 5HCM A; 5HEH A; 4QAC A; 3GUA A; 5AFN A; 2XQ8 A; 2BG9 B; 4ZZB A; 3RHW A; 4DBM A; 5L4E A; 2WZY A; 2X00 D; 3C84 A; 5SYO A; 1I9B A; 2W8F A; 4UM3 A; 4XK9 A; 3ZDH A; 4HQP A; 3C79 A; 2WN9 A; 3U8N A; 4UM1 A; 3UU4 A; 3JAD A; 2BJ0 A; 3UU3 A; 2XQ3 A; 3UQ4 A; 5J0Z A; 5AFK A; 3PMZ A; 4ILA A; 4QAB A; 2BYS A; 4XHE A; 4HFB A; 4IRE A; 3WTH A; 5HCJ A; 4HFC A; 3U8J A; 2XNT A; 3RI5 A; 4UXU A; 3U8L A; 2BG9 E; 2XNV A; 3WTN A; 5J5H A; 2XNU A; 4NZB A; 3UU6 A; 4ALX A; 5AFH A; 4HFI A; 3RQU A; 4ZK1 A; 3WTK A; 3WTI A; 3UU5 A; 5J5F A; 5AFM A; 2Y57 A; 5KE4 A; 4AFT A; 4EZ1 A; 2XQ7 A; 2XYS A; 2Y56 A; 4Z91 A; 3RQW A; 2YN6 A; 4ZZC A; 2XQ6 A; 2BG9 C; 5HEU A; 4Z90 A; 2PH9 A; 3EAM A; 3SQ6 A; 4TNW A; 5IUX A; 2BYP A; 3UQ7 A; 2XQA A; 4QH1 A; 4D01 A; 2BR8 A; 5CO5 A; 3ZKR A; 5HEO A; 4AFG A; 4UM3 S; 3WTJ A; 2ZJU A; 4X5T A; 4ZR6 A; 3SQ9 A; 3ZDG A; 4LML A; 3WTM A; 3RIA A; 5J5G A; 5LG3 A; 2Y58 A; 2BYQ A; 5AFL A; 2WNC A; 3RIF A; 4AFH A; 4IL9 A; 1UW6 A; 4ILB A; 4QAA A; 4QH4 A; 5BW2 A; 4A97 A; 2ZJV A; 5KZU A; 3TLV A; 2BG9 A; 4ZJT A; 3TLU A; 3P4W A; 5CFB A; 2Y7Y A; #chains in the Genus database with same CATH topology 4ILC A; 4PIR A; 2BYN A; 4ZJS A; 1UX2 A; 5TVC A; 2PGZ A; 3UU8 A; 4HFH A; 2YMD A; 5L4H A; 5FJV A; 3WIP A; 3TLT A; 3UUB A; 3IGQ A; 4TNV A; 2YKS A; 2QC1 B; 4HFE A; 4WV9 A; 2W8G A; 2XYT A; 3P50 A; 4QH5 A; 3TLS A; 2UZ6 A; 5AFM B; 3PEO A; 2XZ6 A; 4IL4 A; 2WNL A; 5AFJ A; 4UM3 P; 4TWF A; 3U8M A; 5JME A; 3SH1 A; 4FRR A; 3WTL A; 5LXB A; 4LMK A; 4ZRU A; 5HEG A; 5L47 A; 4LMJ A; 2XQ4 A; 3SIO A; 2C9T A; 2VL0 A; 4NPP A; 2Y54 A; 3T4M A; 4BQT A; 3JAE A; 3TLW A; 2BR7 A; 3WTO A; 2YME A; 2XZ5 A; 4HFD A; 4TWH A; 4ZK4 A; 4B5D A; 5HEJ A; 2BYR A; 3LSV A; 5J5I A; 4BFQ A; 4TWD A; 3EHZ A; 4A98 A; 2WNJ A; 4UY2 A; 2YOE A; 2XQ5 A; 2X00 A; 5AIN A; 5BRX A; 1UV6 A; 5BP0 A; 3JAF A; 4F8H A; 4COF A; 2XQ9 A; 3EI0 A; 3U8K A; 5HCM A; 5HEH A; 4QAC A; 3GUA A; 5AFN A; 2XQ8 A; 2BG9 B; 4ZZB A; 3RHW A; 4DBM A; 5L4E A; 2WZY A; 2X00 D; 3C84 A; 5SYO A; 1I9B A; 2W8F A; 4UM3 A; 4XK9 A; 3ZDH A; 4HQP A; 3C79 A; 2WN9 A; 3U8N A; 4UM1 A; 3UU4 A; 3JAD A; 2BJ0 A; 3UU3 A; 2XQ3 A; 3UQ4 A; 5J0Z A; 5AFK A; 3PMZ A; 4ILA A; 4QAB A; 2BYS A; 4XHE A; 4HFB A; 4IRE A; 3WTH A; 5HCJ A; 4HFC A; 3U8J A; 2XNT A; 3RI5 A; 4UXU A; 3U8L A; 2BG9 E; 2XNV A; 3WTN A; 5J5H A; 2XNU A; 4NZB A; 3UU6 A; 4ALX A; 5AFH A; 4HFI A; 3RQU A; 4ZK1 A; 3WTK A; 3WTI A; 3UU5 A; 5J5F A; 5AFM A; 2Y57 A; 5KE4 A; 4AFT A; 4EZ1 A; 2XQ7 A; 2XYS A; 2Y56 A; 4Z91 A; 3RQW A; 2YN6 A; 4ZZC A; 2XQ6 A; 2BG9 C; 5HEU A; 4Z90 A; 2PH9 A; 3EAM A; 3SQ6 A; 4TNW A; 5IUX A; 2BYP A; 3UQ7 A; 2XQA A; 4QH1 A; 4D01 A; 2BR8 A; 5CO5 A; 3ZKR A; 5HEO A; 4AFG A; 4UM3 S; 3WTJ A; 2ZJU A; 4X5T A; 4ZR6 A; 3SQ9 A; 3ZDG A; 4LML A; 3WTM A; 3RIA A; 5J5G A; 5LG3 A; 2Y58 A; 2BYQ A; 5AFL A; 2WNC A; 3RIF A; 4AFH A; 4IL9 A; 1UW6 A; 4ILB A; 4QAA A; 4QH4 A; 5BW2 A; 4A97 A; 2ZJV A; 5KZU A; 3TLV A; 2BG9 A; 4ZJT A; 3TLU A; 3P4W A; 5CFB A; 2Y7Y A; #chains in the Genus database with same CATH homology 4ILC A; 4PIR A; 2BYN A; 4ZJS A; 1UX2 A; 5TVC A; 2PGZ A; 3UU8 A; 4HFH A; 2YMD A; 5L4H A; 5FJV A; 3WIP A; 3TLT A; 3UUB A; 3IGQ A; 4TNV A; 2YKS A; 2QC1 B; 4HFE A; 4WV9 A; 2W8G A; 2XYT A; 3P50 A; 4QH5 A; 3TLS A; 2UZ6 A; 5AFM B; 3PEO A; 2XZ6 A; 4IL4 A; 2WNL A; 5AFJ A; 4UM3 P; 4TWF A; 3U8M A; 5JME A; 3SH1 A; 4FRR A; 3WTL A; 5LXB A; 4LMK A; 4ZRU A; 5HEG A; 5L47 A; 4LMJ A; 2XQ4 A; 3SIO A; 2C9T A; 2VL0 A; 4NPP A; 2Y54 A; 3T4M A; 4BQT A; 3JAE A; 3TLW A; 2BR7 A; 3WTO A; 2YME A; 2XZ5 A; 4HFD A; 4TWH A; 4ZK4 A; 4B5D A; 5HEJ A; 2BYR A; 3LSV A; 5J5I A; 4BFQ A; 4TWD A; 3EHZ A; 4A98 A; 2WNJ A; 4UY2 A; 2YOE A; 2XQ5 A; 2X00 A; 5AIN A; 5BRX A; 1UV6 A; 5BP0 A; 3JAF A; 4F8H A; 4COF A; 2XQ9 A; 3EI0 A; 3U8K A; 5HCM A; 5HEH A; 4QAC A; 3GUA A; 5AFN A; 2XQ8 A; 2BG9 B; 4ZZB A; 3RHW A; 4DBM A; 5L4E A; 2WZY A; 2X00 D; 3C84 A; 5SYO A; 1I9B A; 2W8F A; 4UM3 A; 4XK9 A; 3ZDH A; 4HQP A; 3C79 A; 2WN9 A; 3U8N A; 4UM1 A; 3UU4 A; 3JAD A; 2BJ0 A; 3UU3 A; 2XQ3 A; 3UQ4 A; 5J0Z A; 5AFK A; 3PMZ A; 4ILA A; 4QAB A; 2BYS A; 4XHE A; 4HFB A; 4IRE A; 3WTH A; 5HCJ A; 4HFC A; 3U8J A; 2XNT A; 3RI5 A; 4UXU A; 3U8L A; 2BG9 E; 2XNV A; 3WTN A; 5J5H A; 2XNU A; 4NZB A; 3UU6 A; 4ALX A; 5AFH A; 4HFI A; 3RQU A; 4ZK1 A; 3WTK A; 3WTI A; 3UU5 A; 5J5F A; 5AFM A; 2Y57 A; 5KE4 A; 4AFT A; 4EZ1 A; 2XQ7 A; 2XYS A; 2Y56 A; 4Z91 A; 3RQW A; 2YN6 A; 4ZZC A; 2XQ6 A; 2BG9 C; 5HEU A; 4Z90 A; 2PH9 A; 3EAM A; 3SQ6 A; 4TNW A; 5IUX A; 2BYP A; 3UQ7 A; 2XQA A; 4QH1 A; 4D01 A; 2BR8 A; 5CO5 A; 3ZKR A; 5HEO A; 4AFG A; 4UM3 S; 3WTJ A; 2ZJU A; 4X5T A; 4ZR6 A; 3SQ9 A; 3ZDG A; 4LML A; 3WTM A; 3RIA A; 5J5G A; 5LG3 A; 2Y58 A; 2BYQ A; 5AFL A; 2WNC A; 3RIF A; 4AFH A; 4IL9 A; 1UW6 A; 4ILB A; 4QAA A; 4QH4 A; 5BW2 A; 4A97 A; 2ZJV A; 5KZU A; 3TLV A; 2BG9 A; 4ZJT A; 3TLU A; 3P4W A; 5CFB A; 2Y7Y A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
