4FRRA

X-ray structure of acetylcholine binding protein from aplysia californica in presence of 3-((s)-azetidin-2-ylmethoxy)-5-((1s,2r)-2-(2-methoxyethyl)cyclopropyl)pyridine
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
209
structure length
208
Chain Sequence
LHSQANLMRLKSDLFNRSPYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray structure of Acetylcholine binding protein from Aplysia californica in presence of 3-((S)-azetidin-2-ylmethoxy)-5-((1S,2R)-2-(2-methoxyethyl)cyclopropyl)pyridine
rcsb
molecule tags Acetylcholine binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 50
structure length 208
sequence length 209
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2012-06-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4frrA00
4TNVA 4ZK4A 4ZR6A 3SH1A 2PGZA 3WTHA 3PEOA 2X00A 5L47A 4ZZCA 4X5TA 3WTOA 4UM3P 3C79A 3C84A 4ILAA 4ZJSA 5AFJA 4LMLA 2BYRA 4QAAA 4HQPA 4F8HA 4QH5A 2BYQA 2ZJVA 4Z90A 3UU3A 5J5IA 2XQ7A 4BQTA 2XQ3A 5CO5A 3GUAA 3T4MA 2VL0A 2WNLA 4AFHA 3IGQA 4IREA 2QC1B 2Y57A 4Z91A 3RQUA 3WTNA 1I9BA 5FJVA 3U8NA 5AFLA 3U8JA 5AFHA 4NZBA 4BFQA 2XQ5A 5LG3A 4IL9A 5L4EA 3RIFA 4ZJTA 2Y7YA 2XQ4A 4TWFA 4UXUA 4XHEA 3RIAA 2BR8A 5J0ZA 2BG9C 5HEOA 5L4HA 3U8KA 3UU4A 3ZKRA 3PMZA 2BJ0A 4HFDA 2BR7A 3UU8A 4D01A 5KE4A 4HFBA 5HCMA 4ALXA 1UW6A 5LXBA 3UQ4A 5SYOA 2BG9A 4QACA 2C9TA 4QH1A 5AFNA 4LMKA 3TLSA 5AFKA 5HEGA 4PIRA 5IUXA 5J5HA 4ZRUA 3ZDHA 2BYSA 4DBMA 5HEUA 1UV6A 3EHZA 2WNCA 4EZ1A 2XZ5A 4TNWA 2Y54A 2ZJUA 5BP0A 2BYPA 3WTKA 3UQ7A 3U8MA 5J5FA 3SIOA 2XQ6A 2YN6A 2YMDA 3WTIA 3WIPA 4IL4A 5BW2A 4ILBA 4B5DA 5JMEA 3WTLA 2BYNA 3P50A 5BRXA 4HFEA 5AINA 5HEJA 4UM3A 4ZZBA 4ZK1A 4HFHA 3SQ9A 5AFMA 4HFCA 4UM1A 2PH9A 3UU6A 4LMJA 2W8FA 2XNUA 3JADA 4TWDA 5HCJA 4AFTA 1UX2A 2BG9B 5HEHA 3WTJA 2XQ8A 3EI0A 4ILCA 4COFA 3JAEA 2Y58A 2WN9A 4UY2A 5KZUA 2XYSA 3TLTA 3TLVA 3P4WA 2XNVA 3UU5A 4XK9A 2YOEA 2XQ9A 4AFGA 2XZ6A 3JAFA 3RI5A 2W8GA 3RQWA 3UUBA 2XYTA 5J5GA 2WNJA 4HFIA 2Y56A 3WTMA 2XQAA 2YMEA 3SQ6A 3TLUA 3ZDGA 3EAMA 4TWHA 2UZ6A 4A97A 4QABA 2BG9E 3LSVA 4QH4A 3RHWA 4A98A 3TLWA 2XNTA 4NPPA 4WV9A 5AFMB 2WZYA 2YKSA 3U8LA 4FRRA 5TVCA 2X00D 4UM3S 5CFBA
chains in the Genus database with same CATH superfamily
4TNVA 4ZK4A 4ZR6A 3SH1A 2PGZA 3WTHA 3PEOA 2X00A 5L47A 4ZZCA 4X5TA 3WTOA 4UM3P 3C79A 3C84A 4ILAA 4ZJSA 5AFJA 4LMLA 2BYRA 4QAAA 4HQPA 4F8HA 4QH5A 2BYQA 2ZJVA 4Z90A 3UU3A 5J5IA 2XQ7A 4BQTA 2XQ3A 5CO5A 3GUAA 3T4MA 2VL0A 2WNLA 4AFHA 3IGQA 4IREA 2QC1B 2Y57A 4Z91A 3RQUA 3WTNA 1I9BA 5FJVA 3U8NA 5AFLA 3U8JA 5AFHA 4NZBA 4BFQA 2XQ5A 5LG3A 4IL9A 5L4EA 3RIFA 4ZJTA 2Y7YA 2XQ4A 4TWFA 4UXUA 4XHEA 3RIAA 2BR8A 5J0ZA 2BG9C 5HEOA 5L4HA 3U8KA 3UU4A 3ZKRA 3PMZA 2BJ0A 4HFDA 2BR7A 3UU8A 4D01A 5KE4A 4HFBA 5HCMA 4ALXA 1UW6A 5LXBA 3UQ4A 5SYOA 2BG9A 4QACA 2C9TA 4QH1A 5AFNA 4LMKA 3TLSA 5AFKA 5HEGA 4PIRA 5IUXA 5J5HA 4ZRUA 3ZDHA 2BYSA 4DBMA 5HEUA 1UV6A 3EHZA 2WNCA 4EZ1A 2XZ5A 4TNWA 2Y54A 2ZJUA 5BP0A 2BYPA 3WTKA 3UQ7A 3U8MA 5J5FA 3SIOA 2XQ6A 2YN6A 2YMDA 3WTIA 3WIPA 4IL4A 5BW2A 4ILBA 4B5DA 5JMEA 3WTLA 2BYNA 3P50A 5BRXA 4HFEA 5AINA 5HEJA 4UM3A 4ZZBA 4ZK1A 4HFHA 3SQ9A 5AFMA 4HFCA 4UM1A 2PH9A 3UU6A 4LMJA 2W8FA 2XNUA 3JADA 4TWDA 5HCJA 4AFTA 1UX2A 2BG9B 5HEHA 3WTJA 2XQ8A 3EI0A 4ILCA 4COFA 3JAEA 2Y58A 2WN9A 4UY2A 5KZUA 2XYSA 3TLTA 3TLVA 3P4WA 2XNVA 3UU5A 4XK9A 2YOEA 2XQ9A 4AFGA 2XZ6A 3JAFA 3RI5A 2W8GA 3RQWA 3UUBA 2XYTA 5J5GA 2WNJA 4HFIA 2Y56A 3WTMA 2XQAA 2YMEA 3SQ6A 3TLUA 3ZDGA 3EAMA 4TWHA 2UZ6A 4A97A 4QABA 2BG9E 3LSVA 4QH4A 3RHWA 4A98A 3TLWA 2XNTA 4NPPA 4WV9A 5AFMB 2WZYA 2YKSA 3U8LA 4FRRA 5TVCA 2X00D 4UM3S 5CFBA
chains in the Genus database with same CATH topology
4TNVA 4ZK4A 4ZR6A 3SH1A 2PGZA 3WTHA 3PEOA 2X00A 5L47A 4ZZCA 4X5TA 3WTOA 4UM3P 3C79A 3C84A 4ILAA 4ZJSA 5AFJA 4LMLA 2BYRA 4QAAA 4HQPA 4F8HA 4QH5A 2BYQA 2ZJVA 4Z90A 3UU3A 5J5IA 2XQ7A 4BQTA 2XQ3A 5CO5A 3GUAA 3T4MA 2VL0A 2WNLA 4AFHA 3IGQA 4IREA 2QC1B 2Y57A 4Z91A 3RQUA 3WTNA 1I9BA 5FJVA 3U8NA 5AFLA 3U8JA 5AFHA 4NZBA 4BFQA 2XQ5A 5LG3A 4IL9A 5L4EA 3RIFA 4ZJTA 2Y7YA 2XQ4A 4TWFA 4UXUA 4XHEA 3RIAA 2BR8A 5J0ZA 2BG9C 5HEOA 5L4HA 3U8KA 3UU4A 3ZKRA 3PMZA 2BJ0A 4HFDA 2BR7A 3UU8A 4D01A 5KE4A 4HFBA 5HCMA 4ALXA 1UW6A 5LXBA 3UQ4A 5SYOA 2BG9A 4QACA 2C9TA 4QH1A 5AFNA 4LMKA 3TLSA 5AFKA 5HEGA 4PIRA 5IUXA 5J5HA 4ZRUA 3ZDHA 2BYSA 4DBMA 5HEUA 1UV6A 3EHZA 2WNCA 4EZ1A 2XZ5A 4TNWA 2Y54A 2ZJUA 5BP0A 2BYPA 3WTKA 3UQ7A 3U8MA 5J5FA 3SIOA 2XQ6A 2YN6A 2YMDA 3WTIA 3WIPA 4IL4A 5BW2A 4ILBA 4B5DA 5JMEA 3WTLA 2BYNA 3P50A 5BRXA 4HFEA 5AINA 5HEJA 4UM3A 4ZZBA 4ZK1A 4HFHA 3SQ9A 5AFMA 4HFCA 4UM1A 2PH9A 3UU6A 4LMJA 2W8FA 2XNUA 3JADA 4TWDA 5HCJA 4AFTA 1UX2A 2BG9B 5HEHA 3WTJA 2XQ8A 3EI0A 4ILCA 4COFA 3JAEA 2Y58A 2WN9A 4UY2A 5KZUA 2XYSA 3TLTA 3TLVA 3P4WA 2XNVA 3UU5A 4XK9A 2YOEA 2XQ9A 4AFGA 2XZ6A 3JAFA 3RI5A 2W8GA 3RQWA 3UUBA 2XYTA 5J5GA 2WNJA 4HFIA 2Y56A 3WTMA 2XQAA 2YMEA 3SQ6A 3TLUA 3ZDGA 3EAMA 4TWHA 2UZ6A 4A97A 4QABA 2BG9E 3LSVA 4QH4A 3RHWA 4A98A 3TLWA 2XNTA 4NPPA 4WV9A 5AFMB 2WZYA 2YKSA 3U8LA 4FRRA 5TVCA 2X00D 4UM3S 5CFBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4TNV A;  4ZK4 A;  4ZR6 A;  3SH1 A;  2PGZ A;  3WTH A;  3PEO A;  2X00 A;  5L47 A;  4ZZC A;  4X5T A;  3WTO A;  4UM3 P;  3C79 A;  3C84 A;  4ILA A;  4ZJS A;  5AFJ A;  4LML A;  2BYR A;  4QAA A;  4HQP A;  4F8H A;  4QH5 A;  2BYQ A;  2ZJV A;  4Z90 A;  3UU3 A;  5J5I A;  2XQ7 A;  4BQT A;  2XQ3 A;  5CO5 A;  3GUA A;  3T4M A;  2VL0 A;  2WNL A;  4AFH A;  3IGQ A;  4IRE A;  2QC1 B;  2Y57 A;  4Z91 A;  3RQU A;  3WTN A;  1I9B A;  5FJV A;  3U8N A;  5AFL A;  3U8J A;  5AFH A;  4NZB A;  4BFQ A;  2XQ5 A;  5LG3 A;  4IL9 A;  5L4E A;  3RIF A;  4ZJT A;  2Y7Y A;  2XQ4 A;  4TWF A;  4UXU A;  4XHE A;  3RIA A;  2BR8 A;  5J0Z A;  2BG9 C;  5HEO A;  5L4H A;  3U8K A;  3UU4 A;  3ZKR A;  3PMZ A;  2BJ0 A;  4HFD A;  2BR7 A;  3UU8 A;  4D01 A;  5KE4 A;  4HFB A;  5HCM A;  4ALX A;  1UW6 A;  5LXB A;  3UQ4 A;  5SYO A;  2BG9 A;  4QAC A;  2C9T A;  4QH1 A;  5AFN A;  4LMK A;  3TLS A;  5AFK A;  5HEG A;  4PIR A;  5IUX A;  5J5H A;  4ZRU A;  3ZDH A;  2BYS A;  4DBM A;  5HEU A;  1UV6 A;  3EHZ A;  2WNC A;  4EZ1 A;  2XZ5 A;  4TNW A;  2Y54 A;  2ZJU A;  5BP0 A;  2BYP A;  3WTK A;  3UQ7 A;  3U8M A;  5J5F A;  3SIO A;  2XQ6 A;  2YN6 A;  2YMD A;  3WTI A;  3WIP A;  4IL4 A;  5BW2 A;  4ILB A;  4B5D A;  5JME A;  3WTL A;  2BYN A;  3P50 A;  5BRX A;  4HFE A;  5AIN A;  5HEJ A;  4UM3 A;  4ZZB A;  4ZK1 A;  4HFH A;  3SQ9 A;  5AFM A;  4HFC A;  4UM1 A;  2PH9 A;  3UU6 A;  4LMJ A;  2W8F A;  2XNU A;  3JAD A;  4TWD A;  5HCJ A;  4AFT A;  1UX2 A;  2BG9 B;  5HEH A;  3WTJ A;  2XQ8 A;  3EI0 A;  4ILC A;  4COF A;  3JAE A;  2Y58 A;  2WN9 A;  4UY2 A;  5KZU A;  2XYS A;  3TLT A;  3TLV A;  3P4W A;  2XNV A;  3UU5 A;  4XK9 A;  2YOE A;  2XQ9 A;  4AFG A;  2XZ6 A;  3JAF A;  3RI5 A;  2W8G A;  3RQW A;  3UUB A;  2XYT A;  5J5G A;  2WNJ A;  4HFI A;  2Y56 A;  3WTM A;  2XQA A;  2YME A;  3SQ6 A;  3TLU A;  3ZDG A;  3EAM A;  4TWH A;  2UZ6 A;  4A97 A;  4QAB A;  2BG9 E;  3LSV A;  4QH4 A;  3RHW A;  4A98 A;  3TLW A;  2XNT A;  4NPP A;  4WV9 A;  5AFM B;  2WZY A;  2YKS A;  3U8L A;  4FRR A;  5TVC A;  2X00 D;  4UM3 S;  5CFB A; 
#chains in the Genus database with same CATH topology
 4TNV A;  4ZK4 A;  4ZR6 A;  3SH1 A;  2PGZ A;  3WTH A;  3PEO A;  2X00 A;  5L47 A;  4ZZC A;  4X5T A;  3WTO A;  4UM3 P;  3C79 A;  3C84 A;  4ILA A;  4ZJS A;  5AFJ A;  4LML A;  2BYR A;  4QAA A;  4HQP A;  4F8H A;  4QH5 A;  2BYQ A;  2ZJV A;  4Z90 A;  3UU3 A;  5J5I A;  2XQ7 A;  4BQT A;  2XQ3 A;  5CO5 A;  3GUA A;  3T4M A;  2VL0 A;  2WNL A;  4AFH A;  3IGQ A;  4IRE A;  2QC1 B;  2Y57 A;  4Z91 A;  3RQU A;  3WTN A;  1I9B A;  5FJV A;  3U8N A;  5AFL A;  3U8J A;  5AFH A;  4NZB A;  4BFQ A;  2XQ5 A;  5LG3 A;  4IL9 A;  5L4E A;  3RIF A;  4ZJT A;  2Y7Y A;  2XQ4 A;  4TWF A;  4UXU A;  4XHE A;  3RIA A;  2BR8 A;  5J0Z A;  2BG9 C;  5HEO A;  5L4H A;  3U8K A;  3UU4 A;  3ZKR A;  3PMZ A;  2BJ0 A;  4HFD A;  2BR7 A;  3UU8 A;  4D01 A;  5KE4 A;  4HFB A;  5HCM A;  4ALX A;  1UW6 A;  5LXB A;  3UQ4 A;  5SYO A;  2BG9 A;  4QAC A;  2C9T A;  4QH1 A;  5AFN A;  4LMK A;  3TLS A;  5AFK A;  5HEG A;  4PIR A;  5IUX A;  5J5H A;  4ZRU A;  3ZDH A;  2BYS A;  4DBM A;  5HEU A;  1UV6 A;  3EHZ A;  2WNC A;  4EZ1 A;  2XZ5 A;  4TNW A;  2Y54 A;  2ZJU A;  5BP0 A;  2BYP A;  3WTK A;  3UQ7 A;  3U8M A;  5J5F A;  3SIO A;  2XQ6 A;  2YN6 A;  2YMD A;  3WTI A;  3WIP A;  4IL4 A;  5BW2 A;  4ILB A;  4B5D A;  5JME A;  3WTL A;  2BYN A;  3P50 A;  5BRX A;  4HFE A;  5AIN A;  5HEJ A;  4UM3 A;  4ZZB A;  4ZK1 A;  4HFH A;  3SQ9 A;  5AFM A;  4HFC A;  4UM1 A;  2PH9 A;  3UU6 A;  4LMJ A;  2W8F A;  2XNU A;  3JAD A;  4TWD A;  5HCJ A;  4AFT A;  1UX2 A;  2BG9 B;  5HEH A;  3WTJ A;  2XQ8 A;  3EI0 A;  4ILC A;  4COF A;  3JAE A;  2Y58 A;  2WN9 A;  4UY2 A;  5KZU A;  2XYS A;  3TLT A;  3TLV A;  3P4W A;  2XNV A;  3UU5 A;  4XK9 A;  2YOE A;  2XQ9 A;  4AFG A;  2XZ6 A;  3JAF A;  3RI5 A;  2W8G A;  3RQW A;  3UUB A;  2XYT A;  5J5G A;  2WNJ A;  4HFI A;  2Y56 A;  3WTM A;  2XQA A;  2YME A;  3SQ6 A;  3TLU A;  3ZDG A;  3EAM A;  4TWH A;  2UZ6 A;  4A97 A;  4QAB A;  2BG9 E;  3LSV A;  4QH4 A;  3RHW A;  4A98 A;  3TLW A;  2XNT A;  4NPP A;  4WV9 A;  5AFM B;  2WZY A;  2YKS A;  3U8L A;  4FRR A;  5TVC A;  2X00 D;  4UM3 S;  5CFB A; 
#chains in the Genus database with same CATH homology
 4TNV A;  4ZK4 A;  4ZR6 A;  3SH1 A;  2PGZ A;  3WTH A;  3PEO A;  2X00 A;  5L47 A;  4ZZC A;  4X5T A;  3WTO A;  4UM3 P;  3C79 A;  3C84 A;  4ILA A;  4ZJS A;  5AFJ A;  4LML A;  2BYR A;  4QAA A;  4HQP A;  4F8H A;  4QH5 A;  2BYQ A;  2ZJV A;  4Z90 A;  3UU3 A;  5J5I A;  2XQ7 A;  4BQT A;  2XQ3 A;  5CO5 A;  3GUA A;  3T4M A;  2VL0 A;  2WNL A;  4AFH A;  3IGQ A;  4IRE A;  2QC1 B;  2Y57 A;  4Z91 A;  3RQU A;  3WTN A;  1I9B A;  5FJV A;  3U8N A;  5AFL A;  3U8J A;  5AFH A;  4NZB A;  4BFQ A;  2XQ5 A;  5LG3 A;  4IL9 A;  5L4E A;  3RIF A;  4ZJT A;  2Y7Y A;  2XQ4 A;  4TWF A;  4UXU A;  4XHE A;  3RIA A;  2BR8 A;  5J0Z A;  2BG9 C;  5HEO A;  5L4H A;  3U8K A;  3UU4 A;  3ZKR A;  3PMZ A;  2BJ0 A;  4HFD A;  2BR7 A;  3UU8 A;  4D01 A;  5KE4 A;  4HFB A;  5HCM A;  4ALX A;  1UW6 A;  5LXB A;  3UQ4 A;  5SYO A;  2BG9 A;  4QAC A;  2C9T A;  4QH1 A;  5AFN A;  4LMK A;  3TLS A;  5AFK A;  5HEG A;  4PIR A;  5IUX A;  5J5H A;  4ZRU A;  3ZDH A;  2BYS A;  4DBM A;  5HEU A;  1UV6 A;  3EHZ A;  2WNC A;  4EZ1 A;  2XZ5 A;  4TNW A;  2Y54 A;  2ZJU A;  5BP0 A;  2BYP A;  3WTK A;  3UQ7 A;  3U8M A;  5J5F A;  3SIO A;  2XQ6 A;  2YN6 A;  2YMD A;  3WTI A;  3WIP A;  4IL4 A;  5BW2 A;  4ILB A;  4B5D A;  5JME A;  3WTL A;  2BYN A;  3P50 A;  5BRX A;  4HFE A;  5AIN A;  5HEJ A;  4UM3 A;  4ZZB A;  4ZK1 A;  4HFH A;  3SQ9 A;  5AFM A;  4HFC A;  4UM1 A;  2PH9 A;  3UU6 A;  4LMJ A;  2W8F A;  2XNU A;  3JAD A;  4TWD A;  5HCJ A;  4AFT A;  1UX2 A;  2BG9 B;  5HEH A;  3WTJ A;  2XQ8 A;  3EI0 A;  4ILC A;  4COF A;  3JAE A;  2Y58 A;  2WN9 A;  4UY2 A;  5KZU A;  2XYS A;  3TLT A;  3TLV A;  3P4W A;  2XNV A;  3UU5 A;  4XK9 A;  2YOE A;  2XQ9 A;  4AFG A;  2XZ6 A;  3JAF A;  3RI5 A;  2W8G A;  3RQW A;  3UUB A;  2XYT A;  5J5G A;  2WNJ A;  4HFI A;  2Y56 A;  3WTM A;  2XQA A;  2YME A;  3SQ6 A;  3TLU A;  3ZDG A;  3EAM A;  4TWH A;  2UZ6 A;  4A97 A;  4QAB A;  2BG9 E;  3LSV A;  4QH4 A;  3RHW A;  4A98 A;  3TLW A;  2XNT A;  4NPP A;  4WV9 A;  5AFM B;  2WZY A;  2YKS A;  3U8L A;  4FRR A;  5TVC A;  2X00 D;  4UM3 S;  5CFB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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