The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
42
|
sequence length |
204
|
structure length |
200
|
Chain Sequence |
LDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLAHVVSDGEVQYTPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKK
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Achbp Engineered to Mimic the Alpha4-Alpha4 Binding Pocket in Alpha4Beta2 Nicotinic Acetylcholine Receptors Reveals Interface Specific Interactions Important for Binding and Activity
pubmed doi rcsb |
| molecule tags |
Signaling protein
|
| source organism |
Lymnaea stagnalis
|
| molecule keywords |
ACETYLCHOLINE-BINDING PROTEIN
|
| total genus |
42
|
| structure length |
200
|
| sequence length |
204
|
| chains with identical sequence |
B, C, D, E
|
| ec nomenclature | |
| pdb deposition date | 2014-05-14 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Distorted Sandwich | Acetylcholine Binding Protein; Chain: A, | Neurotransmitter-gated ion-channel ligand-binding domain |
#chains in the Genus database with same CATH superfamily 3WTH A; 4TWH A; 2W8G A; 5HCJ A; 3U8M A; 4XK9 A; 3WTI A; 3UQ4 A; 3WIP A; 4HFI A; 2W8F A; 4TWF A; 4WV9 A; 4QAB A; 5FJV A; 3UQ7 A; 5J5I A; 3RHW A; 2XQ4 A; 3WTN A; 5BRX A; 5AFM B; 2WNJ A; 3U8J A; 4AFG A; 2XQ7 A; 1I9B A; 4TWD A; 2XNV A; 2Y57 A; 4HFC A; 3UU8 A; 5HEH A; 3RQU A; 5BP0 A; 2ZJV A; 2XQ6 A; 5AFK A; 4HFB A; 3JAF A; 5J0Z A; 3PMZ A; 5J5H A; 4ILA A; 4IL9 A; 5KE4 A; 3WTM A; 4COF A; 4ILB A; 3SQ6 A; 3ZDH A; 3U8K A; 3RI5 A; 4D01 A; 5SYO A; 2PGZ A; 2WNL A; 4QAA A; 2XQ9 A; 3WTO A; 5HEJ A; 2VL0 A; 4NPP A; 3U8N A; 4ZJT A; 4UY2 A; 4ZR6 A; 2BG9 E; 4NZB A; 4QH4 A; 2BR8 A; 5AFM A; 5L4H A; 5BW2 A; 2Y58 A; 3U8L A; 2BYQ A; 2WNC A; 2XQ5 A; 3EAM A; 4ILC A; 5AFL A; 3C84 A; 3EI0 A; 3PEO A; 4UXU A; 4HFH A; 2YMD A; 2BJ0 A; 3WTJ A; 3ZKR A; 4AFH A; 5JME A; 2BG9 B; 5KZU A; 2XQA A; 5HCM A; 4UM3 S; 3JAE A; 4FRR A; 2XYS A; 4UM3 P; 2BYN A; 4Z91 A; 3UU5 A; 3C79 A; 2BYP A; 4TNW A; 2WZY A; 3SIO A; 5AFH A; 5LXB A; 5J5F A; 5HEO A; 4BQT A; 3TLT A; 4UM3 A; 4IRE A; 5CFB A; 3SQ9 A; 2X00 D; 4HFD A; 5HEG A; 3ZDG A; 2Y56 A; 1UW6 A; 3UU4 A; 5L47 A; 2YKS A; 5AFJ A; 2XQ8 A; 4HQP A; 3RIA A; 3T4M A; 2ZJU A; 4Z90 A; 4ZK1 A; 4ZZB A; 5LG3 A; 3WTK A; 1UX2 A; 3TLV A; 4HFE A; 3TLU A; 2YN6 A; 5IUX A; 4ZK4 A; 3GUA A; 3WTL A; 2WN9 A; 2BG9 C; 2YME A; 2QC1 B; 5AFN A; 3P4W A; 4LMJ A; 4QAC A; 5J5G A; 4XHE A; 4B5D A; 3IGQ A; 2PH9 A; 2Y7Y A; 3RQW A; 5CO5 A; 2C9T A; 3UUB A; 2YOE A; 4F8H A; 5L4E A; 4AFT A; 4UM1 A; 2BR7 A; 4ZZC A; 3P50 A; 4ZRU A; 3RIF A; 3TLS A; 3EHZ A; 5HEU A; 5TVC A; 3LSV A; 3JAD A; 5AIN A; 4IL4 A; 4LML A; 2XNU A; 4X5T A; 4A98 A; 3TLW A; 2XZ6 A; 2Y54 A; 2BG9 A; 1UV6 A; 2XYT A; 2XQ3 A; 4PIR A; 4QH5 A; 2XZ5 A; 4ALX A; 2BYR A; 4QH1 A; 4TNV A; 2UZ6 A; 2XNT A; 4ZJS A; 3UU3 A; 4BFQ A; 4LMK A; 4DBM A; 4A97 A; 2BYS A; 3SH1 A; 3UU6 A; 2X00 A; 4EZ1 A; #chains in the Genus database with same CATH topology 3WTH A; 4TWH A; 2W8G A; 5HCJ A; 3U8M A; 4XK9 A; 3WTI A; 3UQ4 A; 3WIP A; 4HFI A; 2W8F A; 4TWF A; 4WV9 A; 4QAB A; 5FJV A; 3UQ7 A; 5J5I A; 3RHW A; 2XQ4 A; 3WTN A; 5BRX A; 5AFM B; 2WNJ A; 3U8J A; 4AFG A; 2XQ7 A; 1I9B A; 4TWD A; 2XNV A; 2Y57 A; 4HFC A; 3UU8 A; 5HEH A; 3RQU A; 5BP0 A; 2ZJV A; 2XQ6 A; 5AFK A; 4HFB A; 3JAF A; 5J0Z A; 3PMZ A; 5J5H A; 4ILA A; 4IL9 A; 5KE4 A; 3WTM A; 4COF A; 4ILB A; 3SQ6 A; 3ZDH A; 3U8K A; 3RI5 A; 4D01 A; 5SYO A; 2PGZ A; 2WNL A; 4QAA A; 2XQ9 A; 3WTO A; 5HEJ A; 2VL0 A; 4NPP A; 3U8N A; 4ZJT A; 4UY2 A; 4ZR6 A; 2BG9 E; 4NZB A; 4QH4 A; 2BR8 A; 5AFM A; 5L4H A; 5BW2 A; 2Y58 A; 3U8L A; 2BYQ A; 2WNC A; 2XQ5 A; 3EAM A; 4ILC A; 5AFL A; 3C84 A; 3EI0 A; 3PEO A; 4UXU A; 4HFH A; 2YMD A; 2BJ0 A; 3WTJ A; 3ZKR A; 4AFH A; 5JME A; 2BG9 B; 5KZU A; 2XQA A; 5HCM A; 4UM3 S; 3JAE A; 4FRR A; 2XYS A; 4UM3 P; 2BYN A; 4Z91 A; 3UU5 A; 3C79 A; 2BYP A; 4TNW A; 2WZY A; 3SIO A; 5AFH A; 5LXB A; 5J5F A; 5HEO A; 4BQT A; 3TLT A; 4UM3 A; 4IRE A; 5CFB A; 3SQ9 A; 2X00 D; 4HFD A; 5HEG A; 3ZDG A; 2Y56 A; 1UW6 A; 3UU4 A; 5L47 A; 2YKS A; 5AFJ A; 2XQ8 A; 4HQP A; 3RIA A; 3T4M A; 2ZJU A; 4Z90 A; 4ZK1 A; 4ZZB A; 5LG3 A; 3WTK A; 1UX2 A; 3TLV A; 4HFE A; 3TLU A; 2YN6 A; 5IUX A; 4ZK4 A; 3GUA A; 3WTL A; 2WN9 A; 2BG9 C; 2YME A; 2QC1 B; 5AFN A; 3P4W A; 4LMJ A; 4QAC A; 5J5G A; 4XHE A; 4B5D A; 3IGQ A; 2PH9 A; 2Y7Y A; 3RQW A; 5CO5 A; 2C9T A; 3UUB A; 2YOE A; 4F8H A; 5L4E A; 4AFT A; 4UM1 A; 2BR7 A; 4ZZC A; 3P50 A; 4ZRU A; 3RIF A; 3TLS A; 3EHZ A; 5HEU A; 5TVC A; 3LSV A; 3JAD A; 5AIN A; 4IL4 A; 4LML A; 2XNU A; 4X5T A; 4A98 A; 3TLW A; 2XZ6 A; 2Y54 A; 2BG9 A; 1UV6 A; 2XYT A; 2XQ3 A; 4PIR A; 4QH5 A; 2XZ5 A; 4ALX A; 2BYR A; 4QH1 A; 4TNV A; 2UZ6 A; 2XNT A; 4ZJS A; 3UU3 A; 4BFQ A; 4LMK A; 4DBM A; 4A97 A; 2BYS A; 3SH1 A; 3UU6 A; 2X00 A; 4EZ1 A; #chains in the Genus database with same CATH homology 3WTH A; 4TWH A; 2W8G A; 5HCJ A; 3U8M A; 4XK9 A; 3WTI A; 3UQ4 A; 3WIP A; 4HFI A; 2W8F A; 4TWF A; 4WV9 A; 4QAB A; 5FJV A; 3UQ7 A; 5J5I A; 3RHW A; 2XQ4 A; 3WTN A; 5BRX A; 5AFM B; 2WNJ A; 3U8J A; 4AFG A; 2XQ7 A; 1I9B A; 4TWD A; 2XNV A; 2Y57 A; 4HFC A; 3UU8 A; 5HEH A; 3RQU A; 5BP0 A; 2ZJV A; 2XQ6 A; 5AFK A; 4HFB A; 3JAF A; 5J0Z A; 3PMZ A; 5J5H A; 4ILA A; 4IL9 A; 5KE4 A; 3WTM A; 4COF A; 4ILB A; 3SQ6 A; 3ZDH A; 3U8K A; 3RI5 A; 4D01 A; 5SYO A; 2PGZ A; 2WNL A; 4QAA A; 2XQ9 A; 3WTO A; 5HEJ A; 2VL0 A; 4NPP A; 3U8N A; 4ZJT A; 4UY2 A; 4ZR6 A; 2BG9 E; 4NZB A; 4QH4 A; 2BR8 A; 5AFM A; 5L4H A; 5BW2 A; 2Y58 A; 3U8L A; 2BYQ A; 2WNC A; 2XQ5 A; 3EAM A; 4ILC A; 5AFL A; 3C84 A; 3EI0 A; 3PEO A; 4UXU A; 4HFH A; 2YMD A; 2BJ0 A; 3WTJ A; 3ZKR A; 4AFH A; 5JME A; 2BG9 B; 5KZU A; 2XQA A; 5HCM A; 4UM3 S; 3JAE A; 4FRR A; 2XYS A; 4UM3 P; 2BYN A; 4Z91 A; 3UU5 A; 3C79 A; 2BYP A; 4TNW A; 2WZY A; 3SIO A; 5AFH A; 5LXB A; 5J5F A; 5HEO A; 4BQT A; 3TLT A; 4UM3 A; 4IRE A; 5CFB A; 3SQ9 A; 2X00 D; 4HFD A; 5HEG A; 3ZDG A; 2Y56 A; 1UW6 A; 3UU4 A; 5L47 A; 2YKS A; 5AFJ A; 2XQ8 A; 4HQP A; 3RIA A; 3T4M A; 2ZJU A; 4Z90 A; 4ZK1 A; 4ZZB A; 5LG3 A; 3WTK A; 1UX2 A; 3TLV A; 4HFE A; 3TLU A; 2YN6 A; 5IUX A; 4ZK4 A; 3GUA A; 3WTL A; 2WN9 A; 2BG9 C; 2YME A; 2QC1 B; 5AFN A; 3P4W A; 4LMJ A; 4QAC A; 5J5G A; 4XHE A; 4B5D A; 3IGQ A; 2PH9 A; 2Y7Y A; 3RQW A; 5CO5 A; 2C9T A; 3UUB A; 2YOE A; 4F8H A; 5L4E A; 4AFT A; 4UM1 A; 2BR7 A; 4ZZC A; 3P50 A; 4ZRU A; 3RIF A; 3TLS A; 3EHZ A; 5HEU A; 5TVC A; 3LSV A; 3JAD A; 5AIN A; 4IL4 A; 4LML A; 2XNU A; 4X5T A; 4A98 A; 3TLW A; 2XZ6 A; 2Y54 A; 2BG9 A; 1UV6 A; 2XYT A; 2XQ3 A; 4PIR A; 4QH5 A; 2XZ5 A; 4ALX A; 2BYR A; 4QH1 A; 4TNV A; 2UZ6 A; 2XNT A; 4ZJS A; 3UU3 A; 4BFQ A; 4LMK A; 4DBM A; 4A97 A; 2BYS A; 3SH1 A; 3UU6 A; 2X00 A; 4EZ1 A;
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