4XHEA

Crystal structure of a-achbp in complex with pinnatoxin a
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
216
structure length
216
Chain Sequence
YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 58
structure length 216
sequence length 216
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2015-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4xheA00
4PIRA 4A98A 3P50A 2XYTA 5J5GA 3RI5A 4Z91A 4ZRUA 2BG9B 3U8LA 4AFHA 2Y56A 3WTNA 3JADA 3WTOA 4HFIA 2BYRA 3UU3A 2XYSA 5LG3A 4ZR6A 3UU5A 2YN6A 2XNTA 2XQ4A 4NZBA 5KZUA 5HEGA 3U8JA 5HEOA 3ZKRA 2Y54A 5TVCA 3UU4A 2BYPA 2XNVA 4ZJTA 2PH9A 2BYQA 3C84A 2WNCA 3RIFA 5BP0A 4UM3A 2BG9E 2YMEA 4XHEA 3SH1A 4ILAA 4HFHA 2XQ6A 4F8HA 5J5HA 3GUAA 3PMZA 3TLTA 5AFNA 2Y58A 2UZ6A 4HQPA 4D01A 4FRRA 5AINA 4EZ1A 2BR7A 5L47A 4ZK4A 2XQ5A 3UU6A 4UM1A 2XQ9A 3P4WA 4Z90A 5CFBA 3RQWA 4WV9A 4LMKA 2QC1B 3TLVA 3T4MA 2W8GA 2XQ3A 3TLWA 2BG9A 5KE4A 4ZZBA 5CO5A 4ILCA 4UM3S 4AFGA 5J5IA 2X00A 1UV6A 4UM3P 3WIPA 3EHZA 4IL4A 4HFEA 4AFTA 3WTIA 4BQTA 5IUXA 3ZDGA 2XZ5A 3IGQA 4TNWA 3U8MA 4LMLA 5AFMB 3LSVA 4TNVA 3RIAA 4BFQA 4B5DA 5HEJA 2YMDA 2VL0A 4NPPA 4UXUA 3ZDHA 5HEHA 3TLSA 4ZZCA 4LMJA 3WTLA 2PGZA 2Y57A 5AFMA 5L4EA 3C79A 4QH5A 3WTMA 4HFDA 3JAFA 5BRXA 3U8NA 1I9BA 4ILBA 5HCMA 5AFJA 1UX2A 5L4HA 3SQ9A 3WTHA 3UU8A 2YKSA 2X00D 3JAEA 4QACA 5AFHA 2XQ8A 3TLUA 2BG9C 4A97A 5AFLA 2XQ7A 3WTKA 2YOEA 5BW2A 5HEUA 4QH4A 4HFCA 4COFA 2XZ6A 3EAMA 5J0ZA 3UQ4A 4ZK1A 4TWFA 3RQUA 5JMEA 5AFKA 3SIOA 2WNLA 4QABA 5SYOA 5LXBA 2XQAA 2Y7YA 2WN9A 4XK9A 3SQ6A 3UQ7A 2BYNA 2C9TA 4UY2A 1UW6A 4X5TA 2W8FA 3WTJA 4IREA 4QAAA 4ZJSA 5J5FA 2ZJVA 2WNJA 3PEOA 5FJVA 4TWDA 4HFBA 3RHWA 3U8KA 3UUBA 4IL9A 2BJ0A 2BR8A 2WZYA 3EI0A 4DBMA 4TWHA 2XNUA 4QH1A 2ZJUA 4ALXA 2BYSA 5HCJA
chains in the Genus database with same CATH superfamily
4PIRA 4A98A 3P50A 2XYTA 5J5GA 3RI5A 4Z91A 4ZRUA 2BG9B 3U8LA 4AFHA 2Y56A 3WTNA 3JADA 3WTOA 4HFIA 2BYRA 3UU3A 2XYSA 5LG3A 4ZR6A 3UU5A 2YN6A 2XNTA 2XQ4A 4NZBA 5KZUA 5HEGA 3U8JA 5HEOA 3ZKRA 2Y54A 5TVCA 3UU4A 2BYPA 2XNVA 4ZJTA 2PH9A 2BYQA 3C84A 2WNCA 3RIFA 5BP0A 4UM3A 2BG9E 2YMEA 4XHEA 3SH1A 4ILAA 4HFHA 2XQ6A 4F8HA 5J5HA 3GUAA 3PMZA 3TLTA 5AFNA 2Y58A 2UZ6A 4HQPA 4D01A 4FRRA 5AINA 4EZ1A 2BR7A 5L47A 4ZK4A 2XQ5A 3UU6A 4UM1A 2XQ9A 3P4WA 4Z90A 5CFBA 3RQWA 4WV9A 4LMKA 2QC1B 3TLVA 3T4MA 2W8GA 2XQ3A 3TLWA 2BG9A 5KE4A 4ZZBA 5CO5A 4ILCA 4UM3S 4AFGA 5J5IA 2X00A 1UV6A 4UM3P 3WIPA 3EHZA 4IL4A 4HFEA 4AFTA 3WTIA 4BQTA 5IUXA 3ZDGA 2XZ5A 3IGQA 4TNWA 3U8MA 4LMLA 5AFMB 3LSVA 4TNVA 3RIAA 4BFQA 4B5DA 5HEJA 2YMDA 2VL0A 4NPPA 4UXUA 3ZDHA 5HEHA 3TLSA 4ZZCA 4LMJA 3WTLA 2PGZA 2Y57A 5AFMA 5L4EA 3C79A 4QH5A 3WTMA 4HFDA 3JAFA 5BRXA 3U8NA 1I9BA 4ILBA 5HCMA 5AFJA 1UX2A 5L4HA 3SQ9A 3WTHA 3UU8A 2YKSA 2X00D 3JAEA 4QACA 5AFHA 2XQ8A 3TLUA 2BG9C 4A97A 5AFLA 2XQ7A 3WTKA 2YOEA 5BW2A 5HEUA 4QH4A 4HFCA 4COFA 2XZ6A 3EAMA 5J0ZA 3UQ4A 4ZK1A 4TWFA 3RQUA 5JMEA 5AFKA 3SIOA 2WNLA 4QABA 5SYOA 5LXBA 2XQAA 2Y7YA 2WN9A 4XK9A 3SQ6A 3UQ7A 2BYNA 2C9TA 4UY2A 1UW6A 4X5TA 2W8FA 3WTJA 4IREA 4QAAA 4ZJSA 5J5FA 2ZJVA 2WNJA 3PEOA 5FJVA 4TWDA 4HFBA 3RHWA 3U8KA 3UUBA 4IL9A 2BJ0A 2BR8A 2WZYA 3EI0A 4DBMA 4TWHA 2XNUA 4QH1A 2ZJUA 4ALXA 2BYSA 5HCJA
chains in the Genus database with same CATH topology
4PIRA 4A98A 3P50A 2XYTA 5J5GA 3RI5A 4Z91A 4ZRUA 2BG9B 3U8LA 4AFHA 2Y56A 3WTNA 3JADA 3WTOA 4HFIA 2BYRA 3UU3A 2XYSA 5LG3A 4ZR6A 3UU5A 2YN6A 2XNTA 2XQ4A 4NZBA 5KZUA 5HEGA 3U8JA 5HEOA 3ZKRA 2Y54A 5TVCA 3UU4A 2BYPA 2XNVA 4ZJTA 2PH9A 2BYQA 3C84A 2WNCA 3RIFA 5BP0A 4UM3A 2BG9E 2YMEA 4XHEA 3SH1A 4ILAA 4HFHA 2XQ6A 4F8HA 5J5HA 3GUAA 3PMZA 3TLTA 5AFNA 2Y58A 2UZ6A 4HQPA 4D01A 4FRRA 5AINA 4EZ1A 2BR7A 5L47A 4ZK4A 2XQ5A 3UU6A 4UM1A 2XQ9A 3P4WA 4Z90A 5CFBA 3RQWA 4WV9A 4LMKA 2QC1B 3TLVA 3T4MA 2W8GA 2XQ3A 3TLWA 2BG9A 5KE4A 4ZZBA 5CO5A 4ILCA 4UM3S 4AFGA 5J5IA 2X00A 1UV6A 4UM3P 3WIPA 3EHZA 4IL4A 4HFEA 4AFTA 3WTIA 4BQTA 5IUXA 3ZDGA 2XZ5A 3IGQA 4TNWA 3U8MA 4LMLA 5AFMB 3LSVA 4TNVA 3RIAA 4BFQA 4B5DA 5HEJA 2YMDA 2VL0A 4NPPA 4UXUA 3ZDHA 5HEHA 3TLSA 4ZZCA 4LMJA 3WTLA 2PGZA 2Y57A 5AFMA 5L4EA 3C79A 4QH5A 3WTMA 4HFDA 3JAFA 5BRXA 3U8NA 1I9BA 4ILBA 5HCMA 5AFJA 1UX2A 5L4HA 3SQ9A 3WTHA 3UU8A 2YKSA 2X00D 3JAEA 4QACA 5AFHA 2XQ8A 3TLUA 2BG9C 4A97A 5AFLA 2XQ7A 3WTKA 2YOEA 5BW2A 5HEUA 4QH4A 4HFCA 4COFA 2XZ6A 3EAMA 5J0ZA 3UQ4A 4ZK1A 4TWFA 3RQUA 5JMEA 5AFKA 3SIOA 2WNLA 4QABA 5SYOA 5LXBA 2XQAA 2Y7YA 2WN9A 4XK9A 3SQ6A 3UQ7A 2BYNA 2C9TA 4UY2A 1UW6A 4X5TA 2W8FA 3WTJA 4IREA 4QAAA 4ZJSA 5J5FA 2ZJVA 2WNJA 3PEOA 5FJVA 4TWDA 4HFBA 3RHWA 3U8KA 3UUBA 4IL9A 2BJ0A 2BR8A 2WZYA 3EI0A 4DBMA 4TWHA 2XNUA 4QH1A 2ZJUA 4ALXA 2BYSA 5HCJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PIR A;  4A98 A;  3P50 A;  2XYT A;  5J5G A;  3RI5 A;  4Z91 A;  4ZRU A;  2BG9 B;  3U8L A;  4AFH A;  2Y56 A;  3WTN A;  3JAD A;  3WTO A;  4HFI A;  2BYR A;  3UU3 A;  2XYS A;  5LG3 A;  4ZR6 A;  3UU5 A;  2YN6 A;  2XNT A;  2XQ4 A;  4NZB A;  5KZU A;  5HEG A;  3U8J A;  5HEO A;  3ZKR A;  2Y54 A;  5TVC A;  3UU4 A;  2BYP A;  2XNV A;  4ZJT A;  2PH9 A;  2BYQ A;  3C84 A;  2WNC A;  3RIF A;  5BP0 A;  4UM3 A;  2BG9 E;  2YME A;  4XHE A;  3SH1 A;  4ILA A;  4HFH A;  2XQ6 A;  4F8H A;  5J5H A;  3GUA A;  3PMZ A;  3TLT A;  5AFN A;  2Y58 A;  2UZ6 A;  4HQP A;  4D01 A;  4FRR A;  5AIN A;  4EZ1 A;  2BR7 A;  5L47 A;  4ZK4 A;  2XQ5 A;  3UU6 A;  4UM1 A;  2XQ9 A;  3P4W A;  4Z90 A;  5CFB A;  3RQW A;  4WV9 A;  4LMK A;  2QC1 B;  3TLV A;  3T4M A;  2W8G A;  2XQ3 A;  3TLW A;  2BG9 A;  5KE4 A;  4ZZB A;  5CO5 A;  4ILC A;  4UM3 S;  4AFG A;  5J5I A;  2X00 A;  1UV6 A;  4UM3 P;  3WIP A;  3EHZ A;  4IL4 A;  4HFE A;  4AFT A;  3WTI A;  4BQT A;  5IUX A;  3ZDG A;  2XZ5 A;  3IGQ A;  4TNW A;  3U8M A;  4LML A;  5AFM B;  3LSV A;  4TNV A;  3RIA A;  4BFQ A;  4B5D A;  5HEJ A;  2YMD A;  2VL0 A;  4NPP A;  4UXU A;  3ZDH A;  5HEH A;  3TLS A;  4ZZC A;  4LMJ A;  3WTL A;  2PGZ A;  2Y57 A;  5AFM A;  5L4E A;  3C79 A;  4QH5 A;  3WTM A;  4HFD A;  3JAF A;  5BRX A;  3U8N A;  1I9B A;  4ILB A;  5HCM A;  5AFJ A;  1UX2 A;  5L4H A;  3SQ9 A;  3WTH A;  3UU8 A;  2YKS A;  2X00 D;  3JAE A;  4QAC A;  5AFH A;  2XQ8 A;  3TLU A;  2BG9 C;  4A97 A;  5AFL A;  2XQ7 A;  3WTK A;  2YOE A;  5BW2 A;  5HEU A;  4QH4 A;  4HFC A;  4COF A;  2XZ6 A;  3EAM A;  5J0Z A;  3UQ4 A;  4ZK1 A;  4TWF A;  3RQU A;  5JME A;  5AFK A;  3SIO A;  2WNL A;  4QAB A;  5SYO A;  5LXB A;  2XQA A;  2Y7Y A;  2WN9 A;  4XK9 A;  3SQ6 A;  3UQ7 A;  2BYN A;  2C9T A;  4UY2 A;  1UW6 A;  4X5T A;  2W8F A;  3WTJ A;  4IRE A;  4QAA A;  4ZJS A;  5J5F A;  2ZJV A;  2WNJ A;  3PEO A;  5FJV A;  4TWD A;  4HFB A;  3RHW A;  3U8K A;  3UUB A;  4IL9 A;  2BJ0 A;  2BR8 A;  2WZY A;  3EI0 A;  4DBM A;  4TWH A;  2XNU A;  4QH1 A;  2ZJU A;  4ALX A;  2BYS A;  5HCJ A; 
#chains in the Genus database with same CATH topology
 4PIR A;  4A98 A;  3P50 A;  2XYT A;  5J5G A;  3RI5 A;  4Z91 A;  4ZRU A;  2BG9 B;  3U8L A;  4AFH A;  2Y56 A;  3WTN A;  3JAD A;  3WTO A;  4HFI A;  2BYR A;  3UU3 A;  2XYS A;  5LG3 A;  4ZR6 A;  3UU5 A;  2YN6 A;  2XNT A;  2XQ4 A;  4NZB A;  5KZU A;  5HEG A;  3U8J A;  5HEO A;  3ZKR A;  2Y54 A;  5TVC A;  3UU4 A;  2BYP A;  2XNV A;  4ZJT A;  2PH9 A;  2BYQ A;  3C84 A;  2WNC A;  3RIF A;  5BP0 A;  4UM3 A;  2BG9 E;  2YME A;  4XHE A;  3SH1 A;  4ILA A;  4HFH A;  2XQ6 A;  4F8H A;  5J5H A;  3GUA A;  3PMZ A;  3TLT A;  5AFN A;  2Y58 A;  2UZ6 A;  4HQP A;  4D01 A;  4FRR A;  5AIN A;  4EZ1 A;  2BR7 A;  5L47 A;  4ZK4 A;  2XQ5 A;  3UU6 A;  4UM1 A;  2XQ9 A;  3P4W A;  4Z90 A;  5CFB A;  3RQW A;  4WV9 A;  4LMK A;  2QC1 B;  3TLV A;  3T4M A;  2W8G A;  2XQ3 A;  3TLW A;  2BG9 A;  5KE4 A;  4ZZB A;  5CO5 A;  4ILC A;  4UM3 S;  4AFG A;  5J5I A;  2X00 A;  1UV6 A;  4UM3 P;  3WIP A;  3EHZ A;  4IL4 A;  4HFE A;  4AFT A;  3WTI A;  4BQT A;  5IUX A;  3ZDG A;  2XZ5 A;  3IGQ A;  4TNW A;  3U8M A;  4LML A;  5AFM B;  3LSV A;  4TNV A;  3RIA A;  4BFQ A;  4B5D A;  5HEJ A;  2YMD A;  2VL0 A;  4NPP A;  4UXU A;  3ZDH A;  5HEH A;  3TLS A;  4ZZC A;  4LMJ A;  3WTL A;  2PGZ A;  2Y57 A;  5AFM A;  5L4E A;  3C79 A;  4QH5 A;  3WTM A;  4HFD A;  3JAF A;  5BRX A;  3U8N A;  1I9B A;  4ILB A;  5HCM A;  5AFJ A;  1UX2 A;  5L4H A;  3SQ9 A;  3WTH A;  3UU8 A;  2YKS A;  2X00 D;  3JAE A;  4QAC A;  5AFH A;  2XQ8 A;  3TLU A;  2BG9 C;  4A97 A;  5AFL A;  2XQ7 A;  3WTK A;  2YOE A;  5BW2 A;  5HEU A;  4QH4 A;  4HFC A;  4COF A;  2XZ6 A;  3EAM A;  5J0Z A;  3UQ4 A;  4ZK1 A;  4TWF A;  3RQU A;  5JME A;  5AFK A;  3SIO A;  2WNL A;  4QAB A;  5SYO A;  5LXB A;  2XQA A;  2Y7Y A;  2WN9 A;  4XK9 A;  3SQ6 A;  3UQ7 A;  2BYN A;  2C9T A;  4UY2 A;  1UW6 A;  4X5T A;  2W8F A;  3WTJ A;  4IRE A;  4QAA A;  4ZJS A;  5J5F A;  2ZJV A;  2WNJ A;  3PEO A;  5FJV A;  4TWD A;  4HFB A;  3RHW A;  3U8K A;  3UUB A;  4IL9 A;  2BJ0 A;  2BR8 A;  2WZY A;  3EI0 A;  4DBM A;  4TWH A;  2XNU A;  4QH1 A;  2ZJU A;  4ALX A;  2BYS A;  5HCJ A; 
#chains in the Genus database with same CATH homology
 4PIR A;  4A98 A;  3P50 A;  2XYT A;  5J5G A;  3RI5 A;  4Z91 A;  4ZRU A;  2BG9 B;  3U8L A;  4AFH A;  2Y56 A;  3WTN A;  3JAD A;  3WTO A;  4HFI A;  2BYR A;  3UU3 A;  2XYS A;  5LG3 A;  4ZR6 A;  3UU5 A;  2YN6 A;  2XNT A;  2XQ4 A;  4NZB A;  5KZU A;  5HEG A;  3U8J A;  5HEO A;  3ZKR A;  2Y54 A;  5TVC A;  3UU4 A;  2BYP A;  2XNV A;  4ZJT A;  2PH9 A;  2BYQ A;  3C84 A;  2WNC A;  3RIF A;  5BP0 A;  4UM3 A;  2BG9 E;  2YME A;  4XHE A;  3SH1 A;  4ILA A;  4HFH A;  2XQ6 A;  4F8H A;  5J5H A;  3GUA A;  3PMZ A;  3TLT A;  5AFN A;  2Y58 A;  2UZ6 A;  4HQP A;  4D01 A;  4FRR A;  5AIN A;  4EZ1 A;  2BR7 A;  5L47 A;  4ZK4 A;  2XQ5 A;  3UU6 A;  4UM1 A;  2XQ9 A;  3P4W A;  4Z90 A;  5CFB A;  3RQW A;  4WV9 A;  4LMK A;  2QC1 B;  3TLV A;  3T4M A;  2W8G A;  2XQ3 A;  3TLW A;  2BG9 A;  5KE4 A;  4ZZB A;  5CO5 A;  4ILC A;  4UM3 S;  4AFG A;  5J5I A;  2X00 A;  1UV6 A;  4UM3 P;  3WIP A;  3EHZ A;  4IL4 A;  4HFE A;  4AFT A;  3WTI A;  4BQT A;  5IUX A;  3ZDG A;  2XZ5 A;  3IGQ A;  4TNW A;  3U8M A;  4LML A;  5AFM B;  3LSV A;  4TNV A;  3RIA A;  4BFQ A;  4B5D A;  5HEJ A;  2YMD A;  2VL0 A;  4NPP A;  4UXU A;  3ZDH A;  5HEH A;  3TLS A;  4ZZC A;  4LMJ A;  3WTL A;  2PGZ A;  2Y57 A;  5AFM A;  5L4E A;  3C79 A;  4QH5 A;  3WTM A;  4HFD A;  3JAF A;  5BRX A;  3U8N A;  1I9B A;  4ILB A;  5HCM A;  5AFJ A;  1UX2 A;  5L4H A;  3SQ9 A;  3WTH A;  3UU8 A;  2YKS A;  2X00 D;  3JAE A;  4QAC A;  5AFH A;  2XQ8 A;  3TLU A;  2BG9 C;  4A97 A;  5AFL A;  2XQ7 A;  3WTK A;  2YOE A;  5BW2 A;  5HEU A;  4QH4 A;  4HFC A;  4COF A;  2XZ6 A;  3EAM A;  5J0Z A;  3UQ4 A;  4ZK1 A;  4TWF A;  3RQU A;  5JME A;  5AFK A;  3SIO A;  2WNL A;  4QAB A;  5SYO A;  5LXB A;  2XQA A;  2Y7Y A;  2WN9 A;  4XK9 A;  3SQ6 A;  3UQ7 A;  2BYN A;  2C9T A;  4UY2 A;  1UW6 A;  4X5T A;  2W8F A;  3WTJ A;  4IRE A;  4QAA A;  4ZJS A;  5J5F A;  2ZJV A;  2WNJ A;  3PEO A;  5FJV A;  4TWD A;  4HFB A;  3RHW A;  3U8K A;  3UUB A;  4IL9 A;  2BJ0 A;  2BR8 A;  2WZY A;  3EI0 A;  4DBM A;  4TWH A;  2XNU A;  4QH1 A;  2ZJU A;  4ALX A;  2BYS A;  5HCJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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