4XHEA

Crystal structure of a-achbp in complex with pinnatoxin a
Total Genus 58
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
58
sequence length
216
structure length
216
Chain Sequence
YKDDDDKLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 58
structure length 216
sequence length 216
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2015-01-05

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4xheA00
1UX2A 2BYPA 4HFIA 5TVCA 3RQUA 2WZYA 2WN9A 4ZRUA 2XZ5A 2Y7YA 4HFCA 2XNTA 4ZJSA 3JAEA 4UY2A 5JMEA 2XNUA 2WNCA 5BRXA 5CFBA 3WTHA 5BP0A 3P4WA 4TWHA 4EZ1A 3UUBA 4ZZCA 4LMJA 3RI5A 4LMKA 2BG9B 5HEJA 2BR8A 1I9BA 3EAMA 3TLVA 3SQ9A 4PIRA 2YN6A 2XQ5A 4HFEA 5J5IA 4ZJTA 4FRRA 2XQ3A 2XQ7A 4UM1A 2XZ6A 5AFJA 5AFHA 4IREA 4HQPA 5L47A 5HEHA 3C79A 2BYQA 4TWDA 2C9TA 2BG9E 3UU5A 4Z90A 3WTJA 5L4EA 5HEOA 3SH1A 3ZDHA 3C84A 1UV6A 3RQWA 3IGQA 2YKSA 5IUXA 2WNLA 3JAFA 4UXUA 3TLUA 4AFHA 4BQTA 3UU4A 3PEOA 2W8GA 5LXBA 5J5GA 3WTNA 5KZUA 2XYTA 2BYNA 2XQ4A 2Y57A 2Y54A 3U8MA 2QC1B 4QH4A 2YOEA 5HCJA 2W8FA 4IL9A 2UZ6A 2X00A 2ZJUA 2XYSA 4IL4A 4ZZBA 2XQ9A 3ZKRA 4B5DA 4F8HA 5AFKA 5LG3A 5AFLA 2X00D 3WIPA 3UU3A 5J5HA 4ILCA 1UW6A 2Y56A 3TLWA 4AFTA 4ILBA 4TNVA 4HFBA 5CO5A 3WTIA 4BFQA 3T4MA 4XK9A 4UM3P 3WTLA 2BYSA 5L4HA 4QAAA 2BYRA 4A98A 3LSVA 4NZBA 3EI0A 3WTOA 3RIAA 2XQ8A 5J0ZA 4COFA 4X5TA 4XHEA 4ALXA 4ZK1A 4ZR6A 3WTKA 4QH5A 5AFMB 3U8JA 2BJ0A 3UU6A 2YMDA 4TNWA 4QABA 2XNVA 4QACA 4A97A 4Z91A 2BG9C 5HEGA 3UU8A 5SYOA 2XQ6A 2XQAA 4LMLA 2PH9A 3RIFA 5AFMA 3U8LA 3TLTA 4NPPA 2VL0A 2BR7A 3GUAA 4ZK4A 3UQ7A 3EHZA 5AFNA 2YMEA 3TLSA 4UM3S 5KE4A 3UQ4A 5AINA 2Y58A 3ZDGA 5FJVA 3P50A 4HFDA 4DBMA 3U8NA 4D01A 4HFHA 5BW2A 2ZJVA 3SQ6A 4QH1A 4AFGA 3PMZA 4ILAA 5J5FA 3JADA 3RHWA 2WNJA 2BG9A 3U8KA 3WTMA 5HCMA 2PGZA 3SIOA 4TWFA 4UM3A 5HEUA 4WV9A
chains in the Genus database with same CATH superfamily
1UX2A 2BYPA 4HFIA 5TVCA 3RQUA 2WZYA 2WN9A 4ZRUA 2XZ5A 2Y7YA 4HFCA 2XNTA 4ZJSA 3JAEA 4UY2A 5JMEA 2XNUA 2WNCA 5BRXA 5CFBA 3WTHA 5BP0A 3P4WA 4TWHA 4EZ1A 3UUBA 4ZZCA 4LMJA 3RI5A 4LMKA 2BG9B 5HEJA 2BR8A 1I9BA 3EAMA 3TLVA 3SQ9A 4PIRA 2YN6A 2XQ5A 4HFEA 5J5IA 4ZJTA 4FRRA 2XQ3A 2XQ7A 4UM1A 2XZ6A 5AFJA 5AFHA 4IREA 4HQPA 5L47A 5HEHA 3C79A 2BYQA 4TWDA 2C9TA 2BG9E 3UU5A 4Z90A 3WTJA 5L4EA 5HEOA 3SH1A 3ZDHA 3C84A 1UV6A 3RQWA 3IGQA 2YKSA 5IUXA 2WNLA 3JAFA 4UXUA 3TLUA 4AFHA 4BQTA 3UU4A 3PEOA 2W8GA 5LXBA 5J5GA 3WTNA 5KZUA 2XYTA 2BYNA 2XQ4A 2Y57A 2Y54A 3U8MA 2QC1B 4QH4A 2YOEA 5HCJA 2W8FA 4IL9A 2UZ6A 2X00A 2ZJUA 2XYSA 4IL4A 4ZZBA 2XQ9A 3ZKRA 4B5DA 4F8HA 5AFKA 5LG3A 5AFLA 2X00D 3WIPA 3UU3A 5J5HA 4ILCA 1UW6A 2Y56A 3TLWA 4AFTA 4ILBA 4TNVA 4HFBA 5CO5A 3WTIA 4BFQA 3T4MA 4XK9A 4UM3P 3WTLA 2BYSA 5L4HA 4QAAA 2BYRA 4A98A 3LSVA 4NZBA 3EI0A 3WTOA 3RIAA 2XQ8A 5J0ZA 4COFA 4X5TA 4XHEA 4ALXA 4ZK1A 4ZR6A 3WTKA 4QH5A 5AFMB 3U8JA 2BJ0A 3UU6A 2YMDA 4TNWA 4QABA 2XNVA 4QACA 4A97A 4Z91A 2BG9C 5HEGA 3UU8A 5SYOA 2XQ6A 2XQAA 4LMLA 2PH9A 3RIFA 5AFMA 3U8LA 3TLTA 4NPPA 2VL0A 2BR7A 3GUAA 4ZK4A 3UQ7A 3EHZA 5AFNA 2YMEA 3TLSA 4UM3S 5KE4A 3UQ4A 5AINA 2Y58A 3ZDGA 5FJVA 3P50A 4HFDA 4DBMA 3U8NA 4D01A 4HFHA 5BW2A 2ZJVA 3SQ6A 4QH1A 4AFGA 3PMZA 4ILAA 5J5FA 3JADA 3RHWA 2WNJA 2BG9A 3U8KA 3WTMA 5HCMA 2PGZA 3SIOA 4TWFA 4UM3A 5HEUA 4WV9A
chains in the Genus database with same CATH topology
1UX2A 2BYPA 4HFIA 5TVCA 3RQUA 2WZYA 2WN9A 4ZRUA 2XZ5A 2Y7YA 4HFCA 2XNTA 4ZJSA 3JAEA 4UY2A 5JMEA 2XNUA 2WNCA 5BRXA 5CFBA 3WTHA 5BP0A 3P4WA 4TWHA 4EZ1A 3UUBA 4ZZCA 4LMJA 3RI5A 4LMKA 2BG9B 5HEJA 2BR8A 1I9BA 3EAMA 3TLVA 3SQ9A 4PIRA 2YN6A 2XQ5A 4HFEA 5J5IA 4ZJTA 4FRRA 2XQ3A 2XQ7A 4UM1A 2XZ6A 5AFJA 5AFHA 4IREA 4HQPA 5L47A 5HEHA 3C79A 2BYQA 4TWDA 2C9TA 2BG9E 3UU5A 4Z90A 3WTJA 5L4EA 5HEOA 3SH1A 3ZDHA 3C84A 1UV6A 3RQWA 3IGQA 2YKSA 5IUXA 2WNLA 3JAFA 4UXUA 3TLUA 4AFHA 4BQTA 3UU4A 3PEOA 2W8GA 5LXBA 5J5GA 3WTNA 5KZUA 2XYTA 2BYNA 2XQ4A 2Y57A 2Y54A 3U8MA 2QC1B 4QH4A 2YOEA 5HCJA 2W8FA 4IL9A 2UZ6A 2X00A 2ZJUA 2XYSA 4IL4A 4ZZBA 2XQ9A 3ZKRA 4B5DA 4F8HA 5AFKA 5LG3A 5AFLA 2X00D 3WIPA 3UU3A 5J5HA 4ILCA 1UW6A 2Y56A 3TLWA 4AFTA 4ILBA 4TNVA 4HFBA 5CO5A 3WTIA 4BFQA 3T4MA 4XK9A 4UM3P 3WTLA 2BYSA 5L4HA 4QAAA 2BYRA 4A98A 3LSVA 4NZBA 3EI0A 3WTOA 3RIAA 2XQ8A 5J0ZA 4COFA 4X5TA 4XHEA 4ALXA 4ZK1A 4ZR6A 3WTKA 4QH5A 5AFMB 3U8JA 2BJ0A 3UU6A 2YMDA 4TNWA 4QABA 2XNVA 4QACA 4A97A 4Z91A 2BG9C 5HEGA 3UU8A 5SYOA 2XQ6A 2XQAA 4LMLA 2PH9A 3RIFA 5AFMA 3U8LA 3TLTA 4NPPA 2VL0A 2BR7A 3GUAA 4ZK4A 3UQ7A 3EHZA 5AFNA 2YMEA 3TLSA 4UM3S 5KE4A 3UQ4A 5AINA 2Y58A 3ZDGA 5FJVA 3P50A 4HFDA 4DBMA 3U8NA 4D01A 4HFHA 5BW2A 2ZJVA 3SQ6A 4QH1A 4AFGA 3PMZA 4ILAA 5J5FA 3JADA 3RHWA 2WNJA 2BG9A 3U8KA 3WTMA 5HCMA 2PGZA 3SIOA 4TWFA 4UM3A 5HEUA 4WV9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1UX2 A;  2BYP A;  4HFI A;  5TVC A;  3RQU A;  2WZY A;  2WN9 A;  4ZRU A;  2XZ5 A;  2Y7Y A;  4HFC A;  2XNT A;  4ZJS A;  3JAE A;  4UY2 A;  5JME A;  2XNU A;  2WNC A;  5BRX A;  5CFB A;  3WTH A;  5BP0 A;  3P4W A;  4TWH A;  4EZ1 A;  3UUB A;  4ZZC A;  4LMJ A;  3RI5 A;  4LMK A;  2BG9 B;  5HEJ A;  2BR8 A;  1I9B A;  3EAM A;  3TLV A;  3SQ9 A;  4PIR A;  2YN6 A;  2XQ5 A;  4HFE A;  5J5I A;  4ZJT A;  4FRR A;  2XQ3 A;  2XQ7 A;  4UM1 A;  2XZ6 A;  5AFJ A;  5AFH A;  4IRE A;  4HQP A;  5L47 A;  5HEH A;  3C79 A;  2BYQ A;  4TWD A;  2C9T A;  2BG9 E;  3UU5 A;  4Z90 A;  3WTJ A;  5L4E A;  5HEO A;  3SH1 A;  3ZDH A;  3C84 A;  1UV6 A;  3RQW A;  3IGQ A;  2YKS A;  5IUX A;  2WNL A;  3JAF A;  4UXU A;  3TLU A;  4AFH A;  4BQT A;  3UU4 A;  3PEO A;  2W8G A;  5LXB A;  5J5G A;  3WTN A;  5KZU A;  2XYT A;  2BYN A;  2XQ4 A;  2Y57 A;  2Y54 A;  3U8M A;  2QC1 B;  4QH4 A;  2YOE A;  5HCJ A;  2W8F A;  4IL9 A;  2UZ6 A;  2X00 A;  2ZJU A;  2XYS A;  4IL4 A;  4ZZB A;  2XQ9 A;  3ZKR A;  4B5D A;  4F8H A;  5AFK A;  5LG3 A;  5AFL A;  2X00 D;  3WIP A;  3UU3 A;  5J5H A;  4ILC A;  1UW6 A;  2Y56 A;  3TLW A;  4AFT A;  4ILB A;  4TNV A;  4HFB A;  5CO5 A;  3WTI A;  4BFQ A;  3T4M A;  4XK9 A;  4UM3 P;  3WTL A;  2BYS A;  5L4H A;  4QAA A;  2BYR A;  4A98 A;  3LSV A;  4NZB A;  3EI0 A;  3WTO A;  3RIA A;  2XQ8 A;  5J0Z A;  4COF A;  4X5T A;  4XHE A;  4ALX A;  4ZK1 A;  4ZR6 A;  3WTK A;  4QH5 A;  5AFM B;  3U8J A;  2BJ0 A;  3UU6 A;  2YMD A;  4TNW A;  4QAB A;  2XNV A;  4QAC A;  4A97 A;  4Z91 A;  2BG9 C;  5HEG A;  3UU8 A;  5SYO A;  2XQ6 A;  2XQA A;  4LML A;  2PH9 A;  3RIF A;  5AFM A;  3U8L A;  3TLT A;  4NPP A;  2VL0 A;  2BR7 A;  3GUA A;  4ZK4 A;  3UQ7 A;  3EHZ A;  5AFN A;  2YME A;  3TLS A;  4UM3 S;  5KE4 A;  3UQ4 A;  5AIN A;  2Y58 A;  3ZDG A;  5FJV A;  3P50 A;  4HFD A;  4DBM A;  3U8N A;  4D01 A;  4HFH A;  5BW2 A;  2ZJV A;  3SQ6 A;  4QH1 A;  4AFG A;  3PMZ A;  4ILA A;  5J5F A;  3JAD A;  3RHW A;  2WNJ A;  2BG9 A;  3U8K A;  3WTM A;  5HCM A;  2PGZ A;  3SIO A;  4TWF A;  4UM3 A;  5HEU A;  4WV9 A; 
#chains in the Genus database with same CATH topology
 1UX2 A;  2BYP A;  4HFI A;  5TVC A;  3RQU A;  2WZY A;  2WN9 A;  4ZRU A;  2XZ5 A;  2Y7Y A;  4HFC A;  2XNT A;  4ZJS A;  3JAE A;  4UY2 A;  5JME A;  2XNU A;  2WNC A;  5BRX A;  5CFB A;  3WTH A;  5BP0 A;  3P4W A;  4TWH A;  4EZ1 A;  3UUB A;  4ZZC A;  4LMJ A;  3RI5 A;  4LMK A;  2BG9 B;  5HEJ A;  2BR8 A;  1I9B A;  3EAM A;  3TLV A;  3SQ9 A;  4PIR A;  2YN6 A;  2XQ5 A;  4HFE A;  5J5I A;  4ZJT A;  4FRR A;  2XQ3 A;  2XQ7 A;  4UM1 A;  2XZ6 A;  5AFJ A;  5AFH A;  4IRE A;  4HQP A;  5L47 A;  5HEH A;  3C79 A;  2BYQ A;  4TWD A;  2C9T A;  2BG9 E;  3UU5 A;  4Z90 A;  3WTJ A;  5L4E A;  5HEO A;  3SH1 A;  3ZDH A;  3C84 A;  1UV6 A;  3RQW A;  3IGQ A;  2YKS A;  5IUX A;  2WNL A;  3JAF A;  4UXU A;  3TLU A;  4AFH A;  4BQT A;  3UU4 A;  3PEO A;  2W8G A;  5LXB A;  5J5G A;  3WTN A;  5KZU A;  2XYT A;  2BYN A;  2XQ4 A;  2Y57 A;  2Y54 A;  3U8M A;  2QC1 B;  4QH4 A;  2YOE A;  5HCJ A;  2W8F A;  4IL9 A;  2UZ6 A;  2X00 A;  2ZJU A;  2XYS A;  4IL4 A;  4ZZB A;  2XQ9 A;  3ZKR A;  4B5D A;  4F8H A;  5AFK A;  5LG3 A;  5AFL A;  2X00 D;  3WIP A;  3UU3 A;  5J5H A;  4ILC A;  1UW6 A;  2Y56 A;  3TLW A;  4AFT A;  4ILB A;  4TNV A;  4HFB A;  5CO5 A;  3WTI A;  4BFQ A;  3T4M A;  4XK9 A;  4UM3 P;  3WTL A;  2BYS A;  5L4H A;  4QAA A;  2BYR A;  4A98 A;  3LSV A;  4NZB A;  3EI0 A;  3WTO A;  3RIA A;  2XQ8 A;  5J0Z A;  4COF A;  4X5T A;  4XHE A;  4ALX A;  4ZK1 A;  4ZR6 A;  3WTK A;  4QH5 A;  5AFM B;  3U8J A;  2BJ0 A;  3UU6 A;  2YMD A;  4TNW A;  4QAB A;  2XNV A;  4QAC A;  4A97 A;  4Z91 A;  2BG9 C;  5HEG A;  3UU8 A;  5SYO A;  2XQ6 A;  2XQA A;  4LML A;  2PH9 A;  3RIF A;  5AFM A;  3U8L A;  3TLT A;  4NPP A;  2VL0 A;  2BR7 A;  3GUA A;  4ZK4 A;  3UQ7 A;  3EHZ A;  5AFN A;  2YME A;  3TLS A;  4UM3 S;  5KE4 A;  3UQ4 A;  5AIN A;  2Y58 A;  3ZDG A;  5FJV A;  3P50 A;  4HFD A;  4DBM A;  3U8N A;  4D01 A;  4HFH A;  5BW2 A;  2ZJV A;  3SQ6 A;  4QH1 A;  4AFG A;  3PMZ A;  4ILA A;  5J5F A;  3JAD A;  3RHW A;  2WNJ A;  2BG9 A;  3U8K A;  3WTM A;  5HCM A;  2PGZ A;  3SIO A;  4TWF A;  4UM3 A;  5HEU A;  4WV9 A; 
#chains in the Genus database with same CATH homology
 1UX2 A;  2BYP A;  4HFI A;  5TVC A;  3RQU A;  2WZY A;  2WN9 A;  4ZRU A;  2XZ5 A;  2Y7Y A;  4HFC A;  2XNT A;  4ZJS A;  3JAE A;  4UY2 A;  5JME A;  2XNU A;  2WNC A;  5BRX A;  5CFB A;  3WTH A;  5BP0 A;  3P4W A;  4TWH A;  4EZ1 A;  3UUB A;  4ZZC A;  4LMJ A;  3RI5 A;  4LMK A;  2BG9 B;  5HEJ A;  2BR8 A;  1I9B A;  3EAM A;  3TLV A;  3SQ9 A;  4PIR A;  2YN6 A;  2XQ5 A;  4HFE A;  5J5I A;  4ZJT A;  4FRR A;  2XQ3 A;  2XQ7 A;  4UM1 A;  2XZ6 A;  5AFJ A;  5AFH A;  4IRE A;  4HQP A;  5L47 A;  5HEH A;  3C79 A;  2BYQ A;  4TWD A;  2C9T A;  2BG9 E;  3UU5 A;  4Z90 A;  3WTJ A;  5L4E A;  5HEO A;  3SH1 A;  3ZDH A;  3C84 A;  1UV6 A;  3RQW A;  3IGQ A;  2YKS A;  5IUX A;  2WNL A;  3JAF A;  4UXU A;  3TLU A;  4AFH A;  4BQT A;  3UU4 A;  3PEO A;  2W8G A;  5LXB A;  5J5G A;  3WTN A;  5KZU A;  2XYT A;  2BYN A;  2XQ4 A;  2Y57 A;  2Y54 A;  3U8M A;  2QC1 B;  4QH4 A;  2YOE A;  5HCJ A;  2W8F A;  4IL9 A;  2UZ6 A;  2X00 A;  2ZJU A;  2XYS A;  4IL4 A;  4ZZB A;  2XQ9 A;  3ZKR A;  4B5D A;  4F8H A;  5AFK A;  5LG3 A;  5AFL A;  2X00 D;  3WIP A;  3UU3 A;  5J5H A;  4ILC A;  1UW6 A;  2Y56 A;  3TLW A;  4AFT A;  4ILB A;  4TNV A;  4HFB A;  5CO5 A;  3WTI A;  4BFQ A;  3T4M A;  4XK9 A;  4UM3 P;  3WTL A;  2BYS A;  5L4H A;  4QAA A;  2BYR A;  4A98 A;  3LSV A;  4NZB A;  3EI0 A;  3WTO A;  3RIA A;  2XQ8 A;  5J0Z A;  4COF A;  4X5T A;  4XHE A;  4ALX A;  4ZK1 A;  4ZR6 A;  3WTK A;  4QH5 A;  5AFM B;  3U8J A;  2BJ0 A;  3UU6 A;  2YMD A;  4TNW A;  4QAB A;  2XNV A;  4QAC A;  4A97 A;  4Z91 A;  2BG9 C;  5HEG A;  3UU8 A;  5SYO A;  2XQ6 A;  2XQA A;  4LML A;  2PH9 A;  3RIF A;  5AFM A;  3U8L A;  3TLT A;  4NPP A;  2VL0 A;  2BR7 A;  3GUA A;  4ZK4 A;  3UQ7 A;  3EHZ A;  5AFN A;  2YME A;  3TLS A;  4UM3 S;  5KE4 A;  3UQ4 A;  5AIN A;  2Y58 A;  3ZDG A;  5FJV A;  3P50 A;  4HFD A;  4DBM A;  3U8N A;  4D01 A;  4HFH A;  5BW2 A;  2ZJV A;  3SQ6 A;  4QH1 A;  4AFG A;  3PMZ A;  4ILA A;  5J5F A;  3JAD A;  3RHW A;  2WNJ A;  2BG9 A;  3U8K A;  3WTM A;  5HCM A;  2PGZ A;  3SIO A;  4TWF A;  4UM3 A;  5HEU A;  4WV9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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