4XK9A

Crystal structure of a-achbp in complex with pinnatoxin g
Total Genus 50
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
50
sequence length
210
structure length
210
Chain Sequence
KLHSQANLMRLKSDLFNRSPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRERR
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Marine Macrocyclic Imines, Pinnatoxins A and G: Structural Determinants and Functional Properties to Distinguish Neuronal alpha 7 from Muscle alpha 12 beta gamma delta nAChRs.
pubmed doi rcsb
molecule tags Acetylcholine-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 50
structure length 210
sequence length 210
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2015-01-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4xk9A00
2ZJUA 1UX2A 5J5HA 3JAFA 2XQ4A 4LMLA 3P4WA 3ZKRA 5HEOA 3WTKA 2C9TA 4QACA 5BW2A 1UV6A 3UU5A 5J5GA 2BYSA 2WN9A 2YN6A 2BYNA 2XQAA 2XQ7A 3UUBA 3WTIA 2BJ0A 5KZUA 3RIFA 3P50A 2XZ5A 4HFHA 3WTHA 2YMEA 5CO5A 4ZRUA 3UQ7A 3TLVA 5JMEA 4UM3S 1UW6A 3JAEA 4UM3P 5HEHA 5IUXA 4UY2A 3EHZA 4QH1A 4ILAA 5LG3A 3TLUA 4UM1A 3JADA 4TWHA 4AFGA 2Y58A 2XNTA 5HCJA 4HFCA 3U8NA 2BYQA 3WIPA 3UQ4A 4ZK1A 4ZJSA 5HCMA 4XHEA 5BRXA 3PMZA 2YKSA 1I9BA 3LSVA 4B5DA 4QH4A 3WTOA 3ZDHA 5AFLA 5AFMB 3U8JA 5J5FA 5AFHA 3PEOA 3SH1A 4ILCA 5CFBA 4QAAA 4COFA 4TNVA 3U8MA 4IL4A 3U8KA 3UU8A 5AINA 4BQTA 4A98A 2VL0A 3UU3A 4LMJA 5AFMA 4UXUA 4TNWA 5L4HA 2BG9B 4ZJTA 2XNVA 3RQUA 4TWFA 4F8HA 5AFNA 2XYTA 3IGQA 3UU4A 4QH5A 2BR8A 5J0ZA 2WNJA 2BR7A 2XQ6A 4HFEA 4IREA 4Z90A 5TVCA 3WTLA 4ALXA 2WZYA 5HEGA 2X00A 4XK9A 2PH9A 3T4MA 2QC1B 2BG9A 3SIOA 4EZ1A 2XQ8A 2YOEA 4ZK4A 4HFDA 3RIAA 5LXBA 3TLWA 4WV9A 3UU6A 2BYPA 4ZR6A 5L47A 2XYSA 4D01A 2PGZA 2Y57A 4FRRA 3GUAA 5SYOA 3RQWA 3WTJA 3C84A 5AFJA 4DBMA 4LMKA 2XZ6A 4ILBA 4A97A 2W8FA 4PIRA 5AFKA 4Z91A 2XQ3A 2YMDA 2Y54A 2Y7YA 5FJVA 3U8LA 3C79A 4HFBA 4HFIA 3RI5A 4ZZCA 2XQ5A 3TLSA 5HEJA 3EI0A 4AFHA 2XNUA 2BYRA 2WNLA 4IL9A 4AFTA 3WTNA 4QABA 4X5TA 5BP0A 2BG9E 2UZ6A 3SQ9A 2X00D 3ZDGA 3TLTA 4NPPA 3EAMA 4NZBA 2Y56A 5HEUA 4ZZBA 5J5IA 4HQPA 4UM3A 2BG9C 3RHWA 4BFQA 2W8GA 2WNCA 3SQ6A 5L4EA 3WTMA 2XQ9A 2ZJVA 4TWDA 5KE4A
chains in the Genus database with same CATH superfamily
2ZJUA 1UX2A 5J5HA 3JAFA 2XQ4A 4LMLA 3P4WA 3ZKRA 5HEOA 3WTKA 2C9TA 4QACA 5BW2A 1UV6A 3UU5A 5J5GA 2BYSA 2WN9A 2YN6A 2BYNA 2XQAA 2XQ7A 3UUBA 3WTIA 2BJ0A 5KZUA 3RIFA 3P50A 2XZ5A 4HFHA 3WTHA 2YMEA 5CO5A 4ZRUA 3UQ7A 3TLVA 5JMEA 4UM3S 1UW6A 3JAEA 4UM3P 5HEHA 5IUXA 4UY2A 3EHZA 4QH1A 4ILAA 5LG3A 3TLUA 4UM1A 3JADA 4TWHA 4AFGA 2Y58A 2XNTA 5HCJA 4HFCA 3U8NA 2BYQA 3WIPA 3UQ4A 4ZK1A 4ZJSA 5HCMA 4XHEA 5BRXA 3PMZA 2YKSA 1I9BA 3LSVA 4B5DA 4QH4A 3WTOA 3ZDHA 5AFLA 5AFMB 3U8JA 5J5FA 5AFHA 3PEOA 3SH1A 4ILCA 5CFBA 4QAAA 4COFA 4TNVA 3U8MA 4IL4A 3U8KA 3UU8A 5AINA 4BQTA 4A98A 2VL0A 3UU3A 4LMJA 5AFMA 4UXUA 4TNWA 5L4HA 2BG9B 4ZJTA 2XNVA 3RQUA 4TWFA 4F8HA 5AFNA 2XYTA 3IGQA 3UU4A 4QH5A 2BR8A 5J0ZA 2WNJA 2BR7A 2XQ6A 4HFEA 4IREA 4Z90A 5TVCA 3WTLA 4ALXA 2WZYA 5HEGA 2X00A 4XK9A 2PH9A 3T4MA 2QC1B 2BG9A 3SIOA 4EZ1A 2XQ8A 2YOEA 4ZK4A 4HFDA 3RIAA 5LXBA 3TLWA 4WV9A 3UU6A 2BYPA 4ZR6A 5L47A 2XYSA 4D01A 2PGZA 2Y57A 4FRRA 3GUAA 5SYOA 3RQWA 3WTJA 3C84A 5AFJA 4DBMA 4LMKA 2XZ6A 4ILBA 4A97A 2W8FA 4PIRA 5AFKA 4Z91A 2XQ3A 2YMDA 2Y54A 2Y7YA 5FJVA 3U8LA 3C79A 4HFBA 4HFIA 3RI5A 4ZZCA 2XQ5A 3TLSA 5HEJA 3EI0A 4AFHA 2XNUA 2BYRA 2WNLA 4IL9A 4AFTA 3WTNA 4QABA 4X5TA 5BP0A 2BG9E 2UZ6A 3SQ9A 2X00D 3ZDGA 3TLTA 4NPPA 3EAMA 4NZBA 2Y56A 5HEUA 4ZZBA 5J5IA 4HQPA 4UM3A 2BG9C 3RHWA 4BFQA 2W8GA 2WNCA 3SQ6A 5L4EA 3WTMA 2XQ9A 2ZJVA 4TWDA 5KE4A
chains in the Genus database with same CATH topology
2ZJUA 1UX2A 5J5HA 3JAFA 2XQ4A 4LMLA 3P4WA 3ZKRA 5HEOA 3WTKA 2C9TA 4QACA 5BW2A 1UV6A 3UU5A 5J5GA 2BYSA 2WN9A 2YN6A 2BYNA 2XQAA 2XQ7A 3UUBA 3WTIA 2BJ0A 5KZUA 3RIFA 3P50A 2XZ5A 4HFHA 3WTHA 2YMEA 5CO5A 4ZRUA 3UQ7A 3TLVA 5JMEA 4UM3S 1UW6A 3JAEA 4UM3P 5HEHA 5IUXA 4UY2A 3EHZA 4QH1A 4ILAA 5LG3A 3TLUA 4UM1A 3JADA 4TWHA 4AFGA 2Y58A 2XNTA 5HCJA 4HFCA 3U8NA 2BYQA 3WIPA 3UQ4A 4ZK1A 4ZJSA 5HCMA 4XHEA 5BRXA 3PMZA 2YKSA 1I9BA 3LSVA 4B5DA 4QH4A 3WTOA 3ZDHA 5AFLA 5AFMB 3U8JA 5J5FA 5AFHA 3PEOA 3SH1A 4ILCA 5CFBA 4QAAA 4COFA 4TNVA 3U8MA 4IL4A 3U8KA 3UU8A 5AINA 4BQTA 4A98A 2VL0A 3UU3A 4LMJA 5AFMA 4UXUA 4TNWA 5L4HA 2BG9B 4ZJTA 2XNVA 3RQUA 4TWFA 4F8HA 5AFNA 2XYTA 3IGQA 3UU4A 4QH5A 2BR8A 5J0ZA 2WNJA 2BR7A 2XQ6A 4HFEA 4IREA 4Z90A 5TVCA 3WTLA 4ALXA 2WZYA 5HEGA 2X00A 4XK9A 2PH9A 3T4MA 2QC1B 2BG9A 3SIOA 4EZ1A 2XQ8A 2YOEA 4ZK4A 4HFDA 3RIAA 5LXBA 3TLWA 4WV9A 3UU6A 2BYPA 4ZR6A 5L47A 2XYSA 4D01A 2PGZA 2Y57A 4FRRA 3GUAA 5SYOA 3RQWA 3WTJA 3C84A 5AFJA 4DBMA 4LMKA 2XZ6A 4ILBA 4A97A 2W8FA 4PIRA 5AFKA 4Z91A 2XQ3A 2YMDA 2Y54A 2Y7YA 5FJVA 3U8LA 3C79A 4HFBA 4HFIA 3RI5A 4ZZCA 2XQ5A 3TLSA 5HEJA 3EI0A 4AFHA 2XNUA 2BYRA 2WNLA 4IL9A 4AFTA 3WTNA 4QABA 4X5TA 5BP0A 2BG9E 2UZ6A 3SQ9A 2X00D 3ZDGA 3TLTA 4NPPA 3EAMA 4NZBA 2Y56A 5HEUA 4ZZBA 5J5IA 4HQPA 4UM3A 2BG9C 3RHWA 4BFQA 2W8GA 2WNCA 3SQ6A 5L4EA 3WTMA 2XQ9A 2ZJVA 4TWDA 5KE4A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZJU A;  1UX2 A;  5J5H A;  3JAF A;  2XQ4 A;  4LML A;  3P4W A;  3ZKR A;  5HEO A;  3WTK A;  2C9T A;  4QAC A;  5BW2 A;  1UV6 A;  3UU5 A;  5J5G A;  2BYS A;  2WN9 A;  2YN6 A;  2BYN A;  2XQA A;  2XQ7 A;  3UUB A;  3WTI A;  2BJ0 A;  5KZU A;  3RIF A;  3P50 A;  2XZ5 A;  4HFH A;  3WTH A;  2YME A;  5CO5 A;  4ZRU A;  3UQ7 A;  3TLV A;  5JME A;  4UM3 S;  1UW6 A;  3JAE A;  4UM3 P;  5HEH A;  5IUX A;  4UY2 A;  3EHZ A;  4QH1 A;  4ILA A;  5LG3 A;  3TLU A;  4UM1 A;  3JAD A;  4TWH A;  4AFG A;  2Y58 A;  2XNT A;  5HCJ A;  4HFC A;  3U8N A;  2BYQ A;  3WIP A;  3UQ4 A;  4ZK1 A;  4ZJS A;  5HCM A;  4XHE A;  5BRX A;  3PMZ A;  2YKS A;  1I9B A;  3LSV A;  4B5D A;  4QH4 A;  3WTO A;  3ZDH A;  5AFL A;  5AFM B;  3U8J A;  5J5F A;  5AFH A;  3PEO A;  3SH1 A;  4ILC A;  5CFB A;  4QAA A;  4COF A;  4TNV A;  3U8M A;  4IL4 A;  3U8K A;  3UU8 A;  5AIN A;  4BQT A;  4A98 A;  2VL0 A;  3UU3 A;  4LMJ A;  5AFM A;  4UXU A;  4TNW A;  5L4H A;  2BG9 B;  4ZJT A;  2XNV A;  3RQU A;  4TWF A;  4F8H A;  5AFN A;  2XYT A;  3IGQ A;  3UU4 A;  4QH5 A;  2BR8 A;  5J0Z A;  2WNJ A;  2BR7 A;  2XQ6 A;  4HFE A;  4IRE A;  4Z90 A;  5TVC A;  3WTL A;  4ALX A;  2WZY A;  5HEG A;  2X00 A;  4XK9 A;  2PH9 A;  3T4M A;  2QC1 B;  2BG9 A;  3SIO A;  4EZ1 A;  2XQ8 A;  2YOE A;  4ZK4 A;  4HFD A;  3RIA A;  5LXB A;  3TLW A;  4WV9 A;  3UU6 A;  2BYP A;  4ZR6 A;  5L47 A;  2XYS A;  4D01 A;  2PGZ A;  2Y57 A;  4FRR A;  3GUA A;  5SYO A;  3RQW A;  3WTJ A;  3C84 A;  5AFJ A;  4DBM A;  4LMK A;  2XZ6 A;  4ILB A;  4A97 A;  2W8F A;  4PIR A;  5AFK A;  4Z91 A;  2XQ3 A;  2YMD A;  2Y54 A;  2Y7Y A;  5FJV A;  3U8L A;  3C79 A;  4HFB A;  4HFI A;  3RI5 A;  4ZZC A;  2XQ5 A;  3TLS A;  5HEJ A;  3EI0 A;  4AFH A;  2XNU A;  2BYR A;  2WNL A;  4IL9 A;  4AFT A;  3WTN A;  4QAB A;  4X5T A;  5BP0 A;  2BG9 E;  2UZ6 A;  3SQ9 A;  2X00 D;  3ZDG A;  3TLT A;  4NPP A;  3EAM A;  4NZB A;  2Y56 A;  5HEU A;  4ZZB A;  5J5I A;  4HQP A;  4UM3 A;  2BG9 C;  3RHW A;  4BFQ A;  2W8G A;  2WNC A;  3SQ6 A;  5L4E A;  3WTM A;  2XQ9 A;  2ZJV A;  4TWD A;  5KE4 A; 
#chains in the Genus database with same CATH topology
 2ZJU A;  1UX2 A;  5J5H A;  3JAF A;  2XQ4 A;  4LML A;  3P4W A;  3ZKR A;  5HEO A;  3WTK A;  2C9T A;  4QAC A;  5BW2 A;  1UV6 A;  3UU5 A;  5J5G A;  2BYS A;  2WN9 A;  2YN6 A;  2BYN A;  2XQA A;  2XQ7 A;  3UUB A;  3WTI A;  2BJ0 A;  5KZU A;  3RIF A;  3P50 A;  2XZ5 A;  4HFH A;  3WTH A;  2YME A;  5CO5 A;  4ZRU A;  3UQ7 A;  3TLV A;  5JME A;  4UM3 S;  1UW6 A;  3JAE A;  4UM3 P;  5HEH A;  5IUX A;  4UY2 A;  3EHZ A;  4QH1 A;  4ILA A;  5LG3 A;  3TLU A;  4UM1 A;  3JAD A;  4TWH A;  4AFG A;  2Y58 A;  2XNT A;  5HCJ A;  4HFC A;  3U8N A;  2BYQ A;  3WIP A;  3UQ4 A;  4ZK1 A;  4ZJS A;  5HCM A;  4XHE A;  5BRX A;  3PMZ A;  2YKS A;  1I9B A;  3LSV A;  4B5D A;  4QH4 A;  3WTO A;  3ZDH A;  5AFL A;  5AFM B;  3U8J A;  5J5F A;  5AFH A;  3PEO A;  3SH1 A;  4ILC A;  5CFB A;  4QAA A;  4COF A;  4TNV A;  3U8M A;  4IL4 A;  3U8K A;  3UU8 A;  5AIN A;  4BQT A;  4A98 A;  2VL0 A;  3UU3 A;  4LMJ A;  5AFM A;  4UXU A;  4TNW A;  5L4H A;  2BG9 B;  4ZJT A;  2XNV A;  3RQU A;  4TWF A;  4F8H A;  5AFN A;  2XYT A;  3IGQ A;  3UU4 A;  4QH5 A;  2BR8 A;  5J0Z A;  2WNJ A;  2BR7 A;  2XQ6 A;  4HFE A;  4IRE A;  4Z90 A;  5TVC A;  3WTL A;  4ALX A;  2WZY A;  5HEG A;  2X00 A;  4XK9 A;  2PH9 A;  3T4M A;  2QC1 B;  2BG9 A;  3SIO A;  4EZ1 A;  2XQ8 A;  2YOE A;  4ZK4 A;  4HFD A;  3RIA A;  5LXB A;  3TLW A;  4WV9 A;  3UU6 A;  2BYP A;  4ZR6 A;  5L47 A;  2XYS A;  4D01 A;  2PGZ A;  2Y57 A;  4FRR A;  3GUA A;  5SYO A;  3RQW A;  3WTJ A;  3C84 A;  5AFJ A;  4DBM A;  4LMK A;  2XZ6 A;  4ILB A;  4A97 A;  2W8F A;  4PIR A;  5AFK A;  4Z91 A;  2XQ3 A;  2YMD A;  2Y54 A;  2Y7Y A;  5FJV A;  3U8L A;  3C79 A;  4HFB A;  4HFI A;  3RI5 A;  4ZZC A;  2XQ5 A;  3TLS A;  5HEJ A;  3EI0 A;  4AFH A;  2XNU A;  2BYR A;  2WNL A;  4IL9 A;  4AFT A;  3WTN A;  4QAB A;  4X5T A;  5BP0 A;  2BG9 E;  2UZ6 A;  3SQ9 A;  2X00 D;  3ZDG A;  3TLT A;  4NPP A;  3EAM A;  4NZB A;  2Y56 A;  5HEU A;  4ZZB A;  5J5I A;  4HQP A;  4UM3 A;  2BG9 C;  3RHW A;  4BFQ A;  2W8G A;  2WNC A;  3SQ6 A;  5L4E A;  3WTM A;  2XQ9 A;  2ZJV A;  4TWD A;  5KE4 A; 
#chains in the Genus database with same CATH homology
 2ZJU A;  1UX2 A;  5J5H A;  3JAF A;  2XQ4 A;  4LML A;  3P4W A;  3ZKR A;  5HEO A;  3WTK A;  2C9T A;  4QAC A;  5BW2 A;  1UV6 A;  3UU5 A;  5J5G A;  2BYS A;  2WN9 A;  2YN6 A;  2BYN A;  2XQA A;  2XQ7 A;  3UUB A;  3WTI A;  2BJ0 A;  5KZU A;  3RIF A;  3P50 A;  2XZ5 A;  4HFH A;  3WTH A;  2YME A;  5CO5 A;  4ZRU A;  3UQ7 A;  3TLV A;  5JME A;  4UM3 S;  1UW6 A;  3JAE A;  4UM3 P;  5HEH A;  5IUX A;  4UY2 A;  3EHZ A;  4QH1 A;  4ILA A;  5LG3 A;  3TLU A;  4UM1 A;  3JAD A;  4TWH A;  4AFG A;  2Y58 A;  2XNT A;  5HCJ A;  4HFC A;  3U8N A;  2BYQ A;  3WIP A;  3UQ4 A;  4ZK1 A;  4ZJS A;  5HCM A;  4XHE A;  5BRX A;  3PMZ A;  2YKS A;  1I9B A;  3LSV A;  4B5D A;  4QH4 A;  3WTO A;  3ZDH A;  5AFL A;  5AFM B;  3U8J A;  5J5F A;  5AFH A;  3PEO A;  3SH1 A;  4ILC A;  5CFB A;  4QAA A;  4COF A;  4TNV A;  3U8M A;  4IL4 A;  3U8K A;  3UU8 A;  5AIN A;  4BQT A;  4A98 A;  2VL0 A;  3UU3 A;  4LMJ A;  5AFM A;  4UXU A;  4TNW A;  5L4H A;  2BG9 B;  4ZJT A;  2XNV A;  3RQU A;  4TWF A;  4F8H A;  5AFN A;  2XYT A;  3IGQ A;  3UU4 A;  4QH5 A;  2BR8 A;  5J0Z A;  2WNJ A;  2BR7 A;  2XQ6 A;  4HFE A;  4IRE A;  4Z90 A;  5TVC A;  3WTL A;  4ALX A;  2WZY A;  5HEG A;  2X00 A;  4XK9 A;  2PH9 A;  3T4M A;  2QC1 B;  2BG9 A;  3SIO A;  4EZ1 A;  2XQ8 A;  2YOE A;  4ZK4 A;  4HFD A;  3RIA A;  5LXB A;  3TLW A;  4WV9 A;  3UU6 A;  2BYP A;  4ZR6 A;  5L47 A;  2XYS A;  4D01 A;  2PGZ A;  2Y57 A;  4FRR A;  3GUA A;  5SYO A;  3RQW A;  3WTJ A;  3C84 A;  5AFJ A;  4DBM A;  4LMK A;  2XZ6 A;  4ILB A;  4A97 A;  2W8F A;  4PIR A;  5AFK A;  4Z91 A;  2XQ3 A;  2YMD A;  2Y54 A;  2Y7Y A;  5FJV A;  3U8L A;  3C79 A;  4HFB A;  4HFI A;  3RI5 A;  4ZZC A;  2XQ5 A;  3TLS A;  5HEJ A;  3EI0 A;  4AFH A;  2XNU A;  2BYR A;  2WNL A;  4IL9 A;  4AFT A;  3WTN A;  4QAB A;  4X5T A;  5BP0 A;  2BG9 E;  2UZ6 A;  3SQ9 A;  2X00 D;  3ZDG A;  3TLT A;  4NPP A;  3EAM A;  4NZB A;  2Y56 A;  5HEU A;  4ZZB A;  5J5I A;  4HQP A;  4UM3 A;  2BG9 C;  3RHW A;  4BFQ A;  2W8G A;  2WNC A;  3SQ6 A;  5L4E A;  3WTM A;  2XQ9 A;  2ZJV A;  4TWD A;  5KE4 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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