The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
49
|
sequence length |
206
|
structure length |
206
|
Chain Sequence |
EHETRLVAKLFKDYSSVVRPVEDHRQVVEVTLGFTLQDIVKADSSTNEVDLVYYEQQRWVDYNLKWNPDDYGGVKKIHIPAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Main immunogenic region structure promotes binding of conformation-dependent myasthenia gravis autoantibodies, nicotinic acetylcholine receptor conformation maturation, and agonist sensitivity.
pubmed doi rcsb |
| molecule keywords |
Acetylcholine receptor subunit alpha,Soluble acetylcholine r
|
| molecule tags |
Immune system
|
| source organism |
Homo sapiens
|
| total genus |
49
|
| structure length |
206
|
| sequence length |
206
|
| chains with identical sequence |
B, C, D, E
|
| ec nomenclature | |
| pdb deposition date | 2015-04-29 |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Distorted Sandwich | Acetylcholine Binding Protein; Chain: A, | Neurotransmitter-gated ion-channel ligand-binding domain |
#chains in the Genus database with same CATH superfamily 2W8G A; 2YMD A; 2XQ8 A; 2XNU A; 2XQ6 A; 2YN6 A; 3UQ4 A; 5LXB A; 3EI0 A; 1UX2 A; 3RHW A; 4AFG A; 3C84 A; 5KZU A; 4ZRU A; 2XNV A; 3WTJ A; 4HFE A; 2XYS A; 5HEO A; 4EZ1 A; 3WTH A; 4HFH A; 3WTM A; 4QH4 A; 4DBM A; 5HCJ A; 3T4M A; 3ZDH A; 3JAF A; 4QH1 A; 4NPP A; 3RIA A; 2X00 A; 3EAM A; 4HFC A; 3UU3 A; 3GUA A; 4HFB A; 5TVC A; 2WNL A; 4HFI A; 4TWF A; 5IUX A; 4Z90 A; 3WTI A; 4IRE A; 3UU4 A; 4BQT A; 4ALX A; 2XZ5 A; 2W8F A; 4B5D A; 4HQP A; 2WNC A; 5L4H A; 4ZZB A; 5J5I A; 2VL0 A; 5J5H A; 3SIO A; 4UXU A; 3U8N A; 2Y54 A; 3WTO A; 5AFK A; 5HEG A; 5J0Z A; 5J5G A; 3RI5 A; 4QAB A; 5AFJ A; 3PMZ A; 4TNV A; 5L4E A; 4UY2 A; 3SQ6 A; 4ZK4 A; 2XYT A; 3EHZ A; 2XQA A; 3IGQ A; 2BG9 E; 4NZB A; 3TLW A; 5HCM A; 5SYO A; 4UM3 S; 2XQ3 A; 5AFM B; 3WTK A; 3P50 A; 2WN9 A; 4QAA A; 2BYP A; 5HEU A; 2BG9 C; 2X00 D; 3UU8 A; 1I9B A; 3TLU A; 5AFM A; 4ILB A; 3SQ9 A; 5AFH A; 5BP0 A; 5BW2 A; 4ZK1 A; 4ILC A; 5FJV A; 4ZR6 A; 4AFT A; 4X5T A; 2XQ7 A; 2Y7Y A; 4PIR A; 2ZJU A; 4ZJT A; 2PH9 A; 4ZZC A; 3TLS A; 3RQW A; 3WTL A; 4TWH A; 4FRR A; 4F8H A; 2BG9 A; 2ZJV A; 4XHE A; 4A97 A; 3TLT A; 3U8M A; 2BR7 A; 3UUB A; 2Y58 A; 5J5F A; 5CFB A; 3UU5 A; 5HEJ A; 2BYR A; 5LG3 A; 5L47 A; 3U8J A; 2XQ9 A; 4BFQ A; 5CO5 A; 2XZ6 A; 3SH1 A; 5BRX A; 2QC1 B; 4UM3 A; 2YKS A; 3ZKR A; 4A98 A; 3U8K A; 5HEH A; 4AFH A; 5AFN A; 4IL4 A; 3WTN A; 2BR8 A; 2BYN A; 5KE4 A; 3RIF A; 3UU6 A; 2UZ6 A; 3PEO A; 3C79 A; 3UQ7 A; 4ILA A; 3U8L A; 4UM1 A; 2BG9 B; 4UM3 P; 3JAE A; 4IL9 A; 3TLV A; 2C9T A; 2Y57 A; 2WNJ A; 2XQ4 A; 4LML A; 2YOE A; 4TNW A; 4WV9 A; 4QH5 A; 2XQ5 A; 4XK9 A; 4LMJ A; 2YME A; 3P4W A; 5AIN A; 1UW6 A; 5AFL A; 1UV6 A; 2XNT A; 2Y56 A; 2WZY A; 4Z91 A; 2BJ0 A; 4TWD A; 4HFD A; 4D01 A; 5JME A; 3LSV A; 2BYS A; 4LMK A; 3WIP A; 4COF A; 2BYQ A; 2PGZ A; 3JAD A; 3RQU A; 4QAC A; 4ZJS A; 3ZDG A; #chains in the Genus database with same CATH topology 2W8G A; 2YMD A; 2XQ8 A; 2XNU A; 2XQ6 A; 2YN6 A; 3UQ4 A; 5LXB A; 3EI0 A; 1UX2 A; 3RHW A; 4AFG A; 3C84 A; 5KZU A; 4ZRU A; 2XNV A; 3WTJ A; 4HFE A; 2XYS A; 5HEO A; 4EZ1 A; 3WTH A; 4HFH A; 3WTM A; 4QH4 A; 4DBM A; 5HCJ A; 3T4M A; 3ZDH A; 3JAF A; 4QH1 A; 4NPP A; 3RIA A; 2X00 A; 3EAM A; 4HFC A; 3UU3 A; 3GUA A; 4HFB A; 5TVC A; 2WNL A; 4HFI A; 4TWF A; 5IUX A; 4Z90 A; 3WTI A; 4IRE A; 3UU4 A; 4BQT A; 4ALX A; 2XZ5 A; 2W8F A; 4B5D A; 4HQP A; 2WNC A; 5L4H A; 4ZZB A; 5J5I A; 2VL0 A; 5J5H A; 3SIO A; 4UXU A; 3U8N A; 2Y54 A; 3WTO A; 5AFK A; 5HEG A; 5J0Z A; 5J5G A; 3RI5 A; 4QAB A; 5AFJ A; 3PMZ A; 4TNV A; 5L4E A; 4UY2 A; 3SQ6 A; 4ZK4 A; 2XYT A; 3EHZ A; 2XQA A; 3IGQ A; 2BG9 E; 4NZB A; 3TLW A; 5HCM A; 5SYO A; 4UM3 S; 2XQ3 A; 5AFM B; 3WTK A; 3P50 A; 2WN9 A; 4QAA A; 2BYP A; 5HEU A; 2BG9 C; 2X00 D; 3UU8 A; 1I9B A; 3TLU A; 5AFM A; 4ILB A; 3SQ9 A; 5AFH A; 5BP0 A; 5BW2 A; 4ZK1 A; 4ILC A; 5FJV A; 4ZR6 A; 4AFT A; 4X5T A; 2XQ7 A; 2Y7Y A; 4PIR A; 2ZJU A; 4ZJT A; 2PH9 A; 4ZZC A; 3TLS A; 3RQW A; 3WTL A; 4TWH A; 4FRR A; 4F8H A; 2BG9 A; 2ZJV A; 4XHE A; 4A97 A; 3TLT A; 3U8M A; 2BR7 A; 3UUB A; 2Y58 A; 5J5F A; 5CFB A; 3UU5 A; 5HEJ A; 2BYR A; 5LG3 A; 5L47 A; 3U8J A; 2XQ9 A; 4BFQ A; 5CO5 A; 2XZ6 A; 3SH1 A; 5BRX A; 2QC1 B; 4UM3 A; 2YKS A; 3ZKR A; 4A98 A; 3U8K A; 5HEH A; 4AFH A; 5AFN A; 4IL4 A; 3WTN A; 2BR8 A; 2BYN A; 5KE4 A; 3RIF A; 3UU6 A; 2UZ6 A; 3PEO A; 3C79 A; 3UQ7 A; 4ILA A; 3U8L A; 4UM1 A; 2BG9 B; 4UM3 P; 3JAE A; 4IL9 A; 3TLV A; 2C9T A; 2Y57 A; 2WNJ A; 2XQ4 A; 4LML A; 2YOE A; 4TNW A; 4WV9 A; 4QH5 A; 2XQ5 A; 4XK9 A; 4LMJ A; 2YME A; 3P4W A; 5AIN A; 1UW6 A; 5AFL A; 1UV6 A; 2XNT A; 2Y56 A; 2WZY A; 4Z91 A; 2BJ0 A; 4TWD A; 4HFD A; 4D01 A; 5JME A; 3LSV A; 2BYS A; 4LMK A; 3WIP A; 4COF A; 2BYQ A; 2PGZ A; 3JAD A; 3RQU A; 4QAC A; 4ZJS A; 3ZDG A; #chains in the Genus database with same CATH homology 2W8G A; 2YMD A; 2XQ8 A; 2XNU A; 2XQ6 A; 2YN6 A; 3UQ4 A; 5LXB A; 3EI0 A; 1UX2 A; 3RHW A; 4AFG A; 3C84 A; 5KZU A; 4ZRU A; 2XNV A; 3WTJ A; 4HFE A; 2XYS A; 5HEO A; 4EZ1 A; 3WTH A; 4HFH A; 3WTM A; 4QH4 A; 4DBM A; 5HCJ A; 3T4M A; 3ZDH A; 3JAF A; 4QH1 A; 4NPP A; 3RIA A; 2X00 A; 3EAM A; 4HFC A; 3UU3 A; 3GUA A; 4HFB A; 5TVC A; 2WNL A; 4HFI A; 4TWF A; 5IUX A; 4Z90 A; 3WTI A; 4IRE A; 3UU4 A; 4BQT A; 4ALX A; 2XZ5 A; 2W8F A; 4B5D A; 4HQP A; 2WNC A; 5L4H A; 4ZZB A; 5J5I A; 2VL0 A; 5J5H A; 3SIO A; 4UXU A; 3U8N A; 2Y54 A; 3WTO A; 5AFK A; 5HEG A; 5J0Z A; 5J5G A; 3RI5 A; 4QAB A; 5AFJ A; 3PMZ A; 4TNV A; 5L4E A; 4UY2 A; 3SQ6 A; 4ZK4 A; 2XYT A; 3EHZ A; 2XQA A; 3IGQ A; 2BG9 E; 4NZB A; 3TLW A; 5HCM A; 5SYO A; 4UM3 S; 2XQ3 A; 5AFM B; 3WTK A; 3P50 A; 2WN9 A; 4QAA A; 2BYP A; 5HEU A; 2BG9 C; 2X00 D; 3UU8 A; 1I9B A; 3TLU A; 5AFM A; 4ILB A; 3SQ9 A; 5AFH A; 5BP0 A; 5BW2 A; 4ZK1 A; 4ILC A; 5FJV A; 4ZR6 A; 4AFT A; 4X5T A; 2XQ7 A; 2Y7Y A; 4PIR A; 2ZJU A; 4ZJT A; 2PH9 A; 4ZZC A; 3TLS A; 3RQW A; 3WTL A; 4TWH A; 4FRR A; 4F8H A; 2BG9 A; 2ZJV A; 4XHE A; 4A97 A; 3TLT A; 3U8M A; 2BR7 A; 3UUB A; 2Y58 A; 5J5F A; 5CFB A; 3UU5 A; 5HEJ A; 2BYR A; 5LG3 A; 5L47 A; 3U8J A; 2XQ9 A; 4BFQ A; 5CO5 A; 2XZ6 A; 3SH1 A; 5BRX A; 2QC1 B; 4UM3 A; 2YKS A; 3ZKR A; 4A98 A; 3U8K A; 5HEH A; 4AFH A; 5AFN A; 4IL4 A; 3WTN A; 2BR8 A; 2BYN A; 5KE4 A; 3RIF A; 3UU6 A; 2UZ6 A; 3PEO A; 3C79 A; 3UQ7 A; 4ILA A; 3U8L A; 4UM1 A; 2BG9 B; 4UM3 P; 3JAE A; 4IL9 A; 3TLV A; 2C9T A; 2Y57 A; 2WNJ A; 2XQ4 A; 4LML A; 2YOE A; 4TNW A; 4WV9 A; 4QH5 A; 2XQ5 A; 4XK9 A; 4LMJ A; 2YME A; 3P4W A; 5AIN A; 1UW6 A; 5AFL A; 1UV6 A; 2XNT A; 2Y56 A; 2WZY A; 4Z91 A; 2BJ0 A; 4TWD A; 4HFD A; 4D01 A; 5JME A; 3LSV A; 2BYS A; 4LMK A; 3WIP A; 4COF A; 2BYQ A; 2PGZ A; 3JAD A; 3RQU A; 4QAC A; 4ZJS A; 3ZDG A;
#similar chains in the Genus database (?% sequence similarity) ...loading similar chains, please wait... #similar chains, but unknotted ...loading similar chains, please wait... #similar chains in the pdb database (?% sequence similarity) ...loading similar chains, please wait...
