4ZJTA

X-ray crystal structure of lymnaea stagnalis acetylcholine binding protein (lsachbp) in complex with 2-thiophenylmethylene anabaseine (2tab)
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
215
structure length
212
Chain Sequence
DDDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPNSDDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKGRSEIL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title X-ray crystal structure of Lymnaea stagnalis acetylcholine binding protein (LsAChBP) in complex with 2-Thiophenylmethylene Anabaseine (2TAB)
rcsb
molecule tags Acetylcholine binding protein
source organism Lymnaea stagnalis
molecule keywords Acetylcholine-binding protein
total genus 49
structure length 212
sequence length 215
chains with identical sequence B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date 2015-04-29

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 4zjtA00
4ZR6A 4HFDA 4QAAA 5L4HA 3PMZA 3RQWA 2WNLA 3WIPA 2XQ5A 4X5TA 3WTOA 4A97A 4ZJTA 2W8GA 4ILAA 2WZYA 2XQ6A 5J0ZA 2XNUA 4NZBA 4XK9A 2W8FA 2XYTA 3U8NA 4COFA 2YMEA 4LMLA 3TLUA 2XZ5A 4QH5A 5SYOA 4QH4A 2WNJA 2BYRA 2YKSA 4QACA 4Z91A 4D01A 4ZZCA 4UM3P 5HEGA 3RIAA 3UU4A 4A98A 4UY2A 3EAMA 3U8LA 1UW6A 2BG9A 5LG3A 4ZK1A 5AFNA 2XQ8A 2VL0A 2C9TA 4NPPA 5HCJA 5J5IA 3RQUA 3UUBA 2Y7YA 4AFHA 3JAFA 5FJVA 4UXUA 2BJ0A 4AFTA 1UX2A 4UM1A 4DBMA 3WTIA 3SQ6A 4IREA 5L4EA 3T4MA 1I9BA 2X00A 3GUAA 5AFKA 3UU5A 3UU3A 3WTLA 5L47A 3SIOA 2PH9A 4XHEA 2BG9B 2XQ3A 3JAEA 5HCMA 5HEJA 3TLTA 5BRXA 4TWFA 5AFMA 4QH1A 2XZ6A 4EZ1A 5AINA 3UQ4A 3SH1A 3TLSA 2BG9E 4WV9A 5AFLA 5AFJA 3WTHA 5BP0A 4QABA 3UQ7A 4ILCA 3P4WA 2XQ9A 3RHWA 2BG9C 4ALXA 2X00D 5CO5A 2BR8A 3PEOA 5AFHA 5HEOA 5IUXA 2BYNA 2BYPA 3EI0A 2YN6A 4TWDA 4BFQA 4TNWA 5AFMB 3U8KA 5JMEA 2WN9A 2XQ7A 3WTKA 3UU8A 4IL9A 5HEUA 2YOEA 4PIRA 2XYSA 4LMJA 4BQTA 3WTJA 5J5GA 3UU6A 4UM3S 3JADA 3C79A 4F8HA 3U8MA 5CFBA 2XQAA 3WTMA 4ILBA 4HFCA 5BW2A 5KE4A 2Y56A 2BYSA 5J5FA 3C84A 3RIFA 4FRRA 3EHZA 5J5HA 1UV6A 5KZUA 4ZK4A 4TNVA 4HFIA 2Y57A 5LXBA 4UM3A 4HFHA 3ZDGA 4HFBA 3P50A 4B5DA 2ZJUA 2PGZA 2ZJVA 2XQ4A 4Z90A 2Y54A 3ZDHA 2XNVA 3IGQA 4ZZBA 3LSVA 4ZJSA 2YMDA 4HQPA 3TLVA 2BR7A 3TLWA 5HEHA 2BYQA 2XNTA 4LMKA 3SQ9A 4HFEA 4ZRUA 3RI5A 2Y58A 4IL4A 4TWHA 2WNCA 3ZKRA 4AFGA 5TVCA 3WTNA 2QC1B 2UZ6A 3U8JA
chains in the Genus database with same CATH superfamily
4ZR6A 4HFDA 4QAAA 5L4HA 3PMZA 3RQWA 2WNLA 3WIPA 2XQ5A 4X5TA 3WTOA 4A97A 4ZJTA 2W8GA 4ILAA 2WZYA 2XQ6A 5J0ZA 2XNUA 4NZBA 4XK9A 2W8FA 2XYTA 3U8NA 4COFA 2YMEA 4LMLA 3TLUA 2XZ5A 4QH5A 5SYOA 4QH4A 2WNJA 2BYRA 2YKSA 4QACA 4Z91A 4D01A 4ZZCA 4UM3P 5HEGA 3RIAA 3UU4A 4A98A 4UY2A 3EAMA 3U8LA 1UW6A 2BG9A 5LG3A 4ZK1A 5AFNA 2XQ8A 2VL0A 2C9TA 4NPPA 5HCJA 5J5IA 3RQUA 3UUBA 2Y7YA 4AFHA 3JAFA 5FJVA 4UXUA 2BJ0A 4AFTA 1UX2A 4UM1A 4DBMA 3WTIA 3SQ6A 4IREA 5L4EA 3T4MA 1I9BA 2X00A 3GUAA 5AFKA 3UU5A 3UU3A 3WTLA 5L47A 3SIOA 2PH9A 4XHEA 2BG9B 2XQ3A 3JAEA 5HCMA 5HEJA 3TLTA 5BRXA 4TWFA 5AFMA 4QH1A 2XZ6A 4EZ1A 5AINA 3UQ4A 3SH1A 3TLSA 2BG9E 4WV9A 5AFLA 5AFJA 3WTHA 5BP0A 4QABA 3UQ7A 4ILCA 3P4WA 2XQ9A 3RHWA 2BG9C 4ALXA 2X00D 5CO5A 2BR8A 3PEOA 5AFHA 5HEOA 5IUXA 2BYNA 2BYPA 3EI0A 2YN6A 4TWDA 4BFQA 4TNWA 5AFMB 3U8KA 5JMEA 2WN9A 2XQ7A 3WTKA 3UU8A 4IL9A 5HEUA 2YOEA 4PIRA 2XYSA 4LMJA 4BQTA 3WTJA 5J5GA 3UU6A 4UM3S 3JADA 3C79A 4F8HA 3U8MA 5CFBA 2XQAA 3WTMA 4ILBA 4HFCA 5BW2A 5KE4A 2Y56A 2BYSA 5J5FA 3C84A 3RIFA 4FRRA 3EHZA 5J5HA 1UV6A 5KZUA 4ZK4A 4TNVA 4HFIA 2Y57A 5LXBA 4UM3A 4HFHA 3ZDGA 4HFBA 3P50A 4B5DA 2ZJUA 2PGZA 2ZJVA 2XQ4A 4Z90A 2Y54A 3ZDHA 2XNVA 3IGQA 4ZZBA 3LSVA 4ZJSA 2YMDA 4HQPA 3TLVA 2BR7A 3TLWA 5HEHA 2BYQA 2XNTA 4LMKA 3SQ9A 4HFEA 4ZRUA 3RI5A 2Y58A 4IL4A 4TWHA 2WNCA 3ZKRA 4AFGA 5TVCA 3WTNA 2QC1B 2UZ6A 3U8JA
chains in the Genus database with same CATH topology
4ZR6A 4HFDA 4QAAA 5L4HA 3PMZA 3RQWA 2WNLA 3WIPA 2XQ5A 4X5TA 3WTOA 4A97A 4ZJTA 2W8GA 4ILAA 2WZYA 2XQ6A 5J0ZA 2XNUA 4NZBA 4XK9A 2W8FA 2XYTA 3U8NA 4COFA 2YMEA 4LMLA 3TLUA 2XZ5A 4QH5A 5SYOA 4QH4A 2WNJA 2BYRA 2YKSA 4QACA 4Z91A 4D01A 4ZZCA 4UM3P 5HEGA 3RIAA 3UU4A 4A98A 4UY2A 3EAMA 3U8LA 1UW6A 2BG9A 5LG3A 4ZK1A 5AFNA 2XQ8A 2VL0A 2C9TA 4NPPA 5HCJA 5J5IA 3RQUA 3UUBA 2Y7YA 4AFHA 3JAFA 5FJVA 4UXUA 2BJ0A 4AFTA 1UX2A 4UM1A 4DBMA 3WTIA 3SQ6A 4IREA 5L4EA 3T4MA 1I9BA 2X00A 3GUAA 5AFKA 3UU5A 3UU3A 3WTLA 5L47A 3SIOA 2PH9A 4XHEA 2BG9B 2XQ3A 3JAEA 5HCMA 5HEJA 3TLTA 5BRXA 4TWFA 5AFMA 4QH1A 2XZ6A 4EZ1A 5AINA 3UQ4A 3SH1A 3TLSA 2BG9E 4WV9A 5AFLA 5AFJA 3WTHA 5BP0A 4QABA 3UQ7A 4ILCA 3P4WA 2XQ9A 3RHWA 2BG9C 4ALXA 2X00D 5CO5A 2BR8A 3PEOA 5AFHA 5HEOA 5IUXA 2BYNA 2BYPA 3EI0A 2YN6A 4TWDA 4BFQA 4TNWA 5AFMB 3U8KA 5JMEA 2WN9A 2XQ7A 3WTKA 3UU8A 4IL9A 5HEUA 2YOEA 4PIRA 2XYSA 4LMJA 4BQTA 3WTJA 5J5GA 3UU6A 4UM3S 3JADA 3C79A 4F8HA 3U8MA 5CFBA 2XQAA 3WTMA 4ILBA 4HFCA 5BW2A 5KE4A 2Y56A 2BYSA 5J5FA 3C84A 3RIFA 4FRRA 3EHZA 5J5HA 1UV6A 5KZUA 4ZK4A 4TNVA 4HFIA 2Y57A 5LXBA 4UM3A 4HFHA 3ZDGA 4HFBA 3P50A 4B5DA 2ZJUA 2PGZA 2ZJVA 2XQ4A 4Z90A 2Y54A 3ZDHA 2XNVA 3IGQA 4ZZBA 3LSVA 4ZJSA 2YMDA 4HQPA 3TLVA 2BR7A 3TLWA 5HEHA 2BYQA 2XNTA 4LMKA 3SQ9A 4HFEA 4ZRUA 3RI5A 2Y58A 4IL4A 4TWHA 2WNCA 3ZKRA 4AFGA 5TVCA 3WTNA 2QC1B 2UZ6A 3U8JA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZR6 A;  4HFD A;  4QAA A;  5L4H A;  3PMZ A;  3RQW A;  2WNL A;  3WIP A;  2XQ5 A;  4X5T A;  3WTO A;  4A97 A;  4ZJT A;  2W8G A;  4ILA A;  2WZY A;  2XQ6 A;  5J0Z A;  2XNU A;  4NZB A;  4XK9 A;  2W8F A;  2XYT A;  3U8N A;  4COF A;  2YME A;  4LML A;  3TLU A;  2XZ5 A;  4QH5 A;  5SYO A;  4QH4 A;  2WNJ A;  2BYR A;  2YKS A;  4QAC A;  4Z91 A;  4D01 A;  4ZZC A;  4UM3 P;  5HEG A;  3RIA A;  3UU4 A;  4A98 A;  4UY2 A;  3EAM A;  3U8L A;  1UW6 A;  2BG9 A;  5LG3 A;  4ZK1 A;  5AFN A;  2XQ8 A;  2VL0 A;  2C9T A;  4NPP A;  5HCJ A;  5J5I A;  3RQU A;  3UUB A;  2Y7Y A;  4AFH A;  3JAF A;  5FJV A;  4UXU A;  2BJ0 A;  4AFT A;  1UX2 A;  4UM1 A;  4DBM A;  3WTI A;  3SQ6 A;  4IRE A;  5L4E A;  3T4M A;  1I9B A;  2X00 A;  3GUA A;  5AFK A;  3UU5 A;  3UU3 A;  3WTL A;  5L47 A;  3SIO A;  2PH9 A;  4XHE A;  2BG9 B;  2XQ3 A;  3JAE A;  5HCM A;  5HEJ A;  3TLT A;  5BRX A;  4TWF A;  5AFM A;  4QH1 A;  2XZ6 A;  4EZ1 A;  5AIN A;  3UQ4 A;  3SH1 A;  3TLS A;  2BG9 E;  4WV9 A;  5AFL A;  5AFJ A;  3WTH A;  5BP0 A;  4QAB A;  3UQ7 A;  4ILC A;  3P4W A;  2XQ9 A;  3RHW A;  2BG9 C;  4ALX A;  2X00 D;  5CO5 A;  2BR8 A;  3PEO A;  5AFH A;  5HEO A;  5IUX A;  2BYN A;  2BYP A;  3EI0 A;  2YN6 A;  4TWD A;  4BFQ A;  4TNW A;  5AFM B;  3U8K A;  5JME A;  2WN9 A;  2XQ7 A;  3WTK A;  3UU8 A;  4IL9 A;  5HEU A;  2YOE A;  4PIR A;  2XYS A;  4LMJ A;  4BQT A;  3WTJ A;  5J5G A;  3UU6 A;  4UM3 S;  3JAD A;  3C79 A;  4F8H A;  3U8M A;  5CFB A;  2XQA A;  3WTM A;  4ILB A;  4HFC A;  5BW2 A;  5KE4 A;  2Y56 A;  2BYS A;  5J5F A;  3C84 A;  3RIF A;  4FRR A;  3EHZ A;  5J5H A;  1UV6 A;  5KZU A;  4ZK4 A;  4TNV A;  4HFI A;  2Y57 A;  5LXB A;  4UM3 A;  4HFH A;  3ZDG A;  4HFB A;  3P50 A;  4B5D A;  2ZJU A;  2PGZ A;  2ZJV A;  2XQ4 A;  4Z90 A;  2Y54 A;  3ZDH A;  2XNV A;  3IGQ A;  4ZZB A;  3LSV A;  4ZJS A;  2YMD A;  4HQP A;  3TLV A;  2BR7 A;  3TLW A;  5HEH A;  2BYQ A;  2XNT A;  4LMK A;  3SQ9 A;  4HFE A;  4ZRU A;  3RI5 A;  2Y58 A;  4IL4 A;  4TWH A;  2WNC A;  3ZKR A;  4AFG A;  5TVC A;  3WTN A;  2QC1 B;  2UZ6 A;  3U8J A; 
#chains in the Genus database with same CATH topology
 4ZR6 A;  4HFD A;  4QAA A;  5L4H A;  3PMZ A;  3RQW A;  2WNL A;  3WIP A;  2XQ5 A;  4X5T A;  3WTO A;  4A97 A;  4ZJT A;  2W8G A;  4ILA A;  2WZY A;  2XQ6 A;  5J0Z A;  2XNU A;  4NZB A;  4XK9 A;  2W8F A;  2XYT A;  3U8N A;  4COF A;  2YME A;  4LML A;  3TLU A;  2XZ5 A;  4QH5 A;  5SYO A;  4QH4 A;  2WNJ A;  2BYR A;  2YKS A;  4QAC A;  4Z91 A;  4D01 A;  4ZZC A;  4UM3 P;  5HEG A;  3RIA A;  3UU4 A;  4A98 A;  4UY2 A;  3EAM A;  3U8L A;  1UW6 A;  2BG9 A;  5LG3 A;  4ZK1 A;  5AFN A;  2XQ8 A;  2VL0 A;  2C9T A;  4NPP A;  5HCJ A;  5J5I A;  3RQU A;  3UUB A;  2Y7Y A;  4AFH A;  3JAF A;  5FJV A;  4UXU A;  2BJ0 A;  4AFT A;  1UX2 A;  4UM1 A;  4DBM A;  3WTI A;  3SQ6 A;  4IRE A;  5L4E A;  3T4M A;  1I9B A;  2X00 A;  3GUA A;  5AFK A;  3UU5 A;  3UU3 A;  3WTL A;  5L47 A;  3SIO A;  2PH9 A;  4XHE A;  2BG9 B;  2XQ3 A;  3JAE A;  5HCM A;  5HEJ A;  3TLT A;  5BRX A;  4TWF A;  5AFM A;  4QH1 A;  2XZ6 A;  4EZ1 A;  5AIN A;  3UQ4 A;  3SH1 A;  3TLS A;  2BG9 E;  4WV9 A;  5AFL A;  5AFJ A;  3WTH A;  5BP0 A;  4QAB A;  3UQ7 A;  4ILC A;  3P4W A;  2XQ9 A;  3RHW A;  2BG9 C;  4ALX A;  2X00 D;  5CO5 A;  2BR8 A;  3PEO A;  5AFH A;  5HEO A;  5IUX A;  2BYN A;  2BYP A;  3EI0 A;  2YN6 A;  4TWD A;  4BFQ A;  4TNW A;  5AFM B;  3U8K A;  5JME A;  2WN9 A;  2XQ7 A;  3WTK A;  3UU8 A;  4IL9 A;  5HEU A;  2YOE A;  4PIR A;  2XYS A;  4LMJ A;  4BQT A;  3WTJ A;  5J5G A;  3UU6 A;  4UM3 S;  3JAD A;  3C79 A;  4F8H A;  3U8M A;  5CFB A;  2XQA A;  3WTM A;  4ILB A;  4HFC A;  5BW2 A;  5KE4 A;  2Y56 A;  2BYS A;  5J5F A;  3C84 A;  3RIF A;  4FRR A;  3EHZ A;  5J5H A;  1UV6 A;  5KZU A;  4ZK4 A;  4TNV A;  4HFI A;  2Y57 A;  5LXB A;  4UM3 A;  4HFH A;  3ZDG A;  4HFB A;  3P50 A;  4B5D A;  2ZJU A;  2PGZ A;  2ZJV A;  2XQ4 A;  4Z90 A;  2Y54 A;  3ZDH A;  2XNV A;  3IGQ A;  4ZZB A;  3LSV A;  4ZJS A;  2YMD A;  4HQP A;  3TLV A;  2BR7 A;  3TLW A;  5HEH A;  2BYQ A;  2XNT A;  4LMK A;  3SQ9 A;  4HFE A;  4ZRU A;  3RI5 A;  2Y58 A;  4IL4 A;  4TWH A;  2WNC A;  3ZKR A;  4AFG A;  5TVC A;  3WTN A;  2QC1 B;  2UZ6 A;  3U8J A; 
#chains in the Genus database with same CATH homology
 4ZR6 A;  4HFD A;  4QAA A;  5L4H A;  3PMZ A;  3RQW A;  2WNL A;  3WIP A;  2XQ5 A;  4X5T A;  3WTO A;  4A97 A;  4ZJT A;  2W8G A;  4ILA A;  2WZY A;  2XQ6 A;  5J0Z A;  2XNU A;  4NZB A;  4XK9 A;  2W8F A;  2XYT A;  3U8N A;  4COF A;  2YME A;  4LML A;  3TLU A;  2XZ5 A;  4QH5 A;  5SYO A;  4QH4 A;  2WNJ A;  2BYR A;  2YKS A;  4QAC A;  4Z91 A;  4D01 A;  4ZZC A;  4UM3 P;  5HEG A;  3RIA A;  3UU4 A;  4A98 A;  4UY2 A;  3EAM A;  3U8L A;  1UW6 A;  2BG9 A;  5LG3 A;  4ZK1 A;  5AFN A;  2XQ8 A;  2VL0 A;  2C9T A;  4NPP A;  5HCJ A;  5J5I A;  3RQU A;  3UUB A;  2Y7Y A;  4AFH A;  3JAF A;  5FJV A;  4UXU A;  2BJ0 A;  4AFT A;  1UX2 A;  4UM1 A;  4DBM A;  3WTI A;  3SQ6 A;  4IRE A;  5L4E A;  3T4M A;  1I9B A;  2X00 A;  3GUA A;  5AFK A;  3UU5 A;  3UU3 A;  3WTL A;  5L47 A;  3SIO A;  2PH9 A;  4XHE A;  2BG9 B;  2XQ3 A;  3JAE A;  5HCM A;  5HEJ A;  3TLT A;  5BRX A;  4TWF A;  5AFM A;  4QH1 A;  2XZ6 A;  4EZ1 A;  5AIN A;  3UQ4 A;  3SH1 A;  3TLS A;  2BG9 E;  4WV9 A;  5AFL A;  5AFJ A;  3WTH A;  5BP0 A;  4QAB A;  3UQ7 A;  4ILC A;  3P4W A;  2XQ9 A;  3RHW A;  2BG9 C;  4ALX A;  2X00 D;  5CO5 A;  2BR8 A;  3PEO A;  5AFH A;  5HEO A;  5IUX A;  2BYN A;  2BYP A;  3EI0 A;  2YN6 A;  4TWD A;  4BFQ A;  4TNW A;  5AFM B;  3U8K A;  5JME A;  2WN9 A;  2XQ7 A;  3WTK A;  3UU8 A;  4IL9 A;  5HEU A;  2YOE A;  4PIR A;  2XYS A;  4LMJ A;  4BQT A;  3WTJ A;  5J5G A;  3UU6 A;  4UM3 S;  3JAD A;  3C79 A;  4F8H A;  3U8M A;  5CFB A;  2XQA A;  3WTM A;  4ILB A;  4HFC A;  5BW2 A;  5KE4 A;  2Y56 A;  2BYS A;  5J5F A;  3C84 A;  3RIF A;  4FRR A;  3EHZ A;  5J5H A;  1UV6 A;  5KZU A;  4ZK4 A;  4TNV A;  4HFI A;  2Y57 A;  5LXB A;  4UM3 A;  4HFH A;  3ZDG A;  4HFB A;  3P50 A;  4B5D A;  2ZJU A;  2PGZ A;  2ZJV A;  2XQ4 A;  4Z90 A;  2Y54 A;  3ZDH A;  2XNV A;  3IGQ A;  4ZZB A;  3LSV A;  4ZJS A;  2YMD A;  4HQP A;  3TLV A;  2BR7 A;  3TLW A;  5HEH A;  2BYQ A;  2XNT A;  4LMK A;  3SQ9 A;  4HFE A;  4ZRU A;  3RI5 A;  2Y58 A;  4IL4 A;  4TWH A;  2WNC A;  3ZKR A;  4AFG A;  5TVC A;  3WTN A;  2QC1 B;  2UZ6 A;  3U8J A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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