5BRX | Genus

Total Genus 48

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	48
sequence length	211
structure length	209
Chain Sequence	DDKLHSQANLMRLKSDLFNRSYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRER

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Acetylcholine binding protein
source organism	Aplysia californica
publication title	Comparisons of Binding Affinities for Neuronal Nicotinic Receptors (NNRs) and AChBPs rcsb
molecule keywords	Soluble acetylcholine receptor
total genus	48
structure length	209
sequence length	211
chains with identical sequence	B, C, D, E, F, G, H, I, J
ec nomenclature
pdb deposition date	2015-06-01

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	5brxA00

5HEUA 1UX2A 3EHZA 2BYQA 4PIRA 2XQ6A 4NZBA 5AINA 4TWFA 3PEOA 2XYSA 4B5DA 4QAAA 2BR7A 2WNCA 3SIOA 2YMEA 3C79A 4HFDA 2WN9A 3T4MA 2X00A 3JAFA 5HEOA 5L4HA 2BG9A 3SH1A 4FRRA 5LG3A 4XK9A 5FJVA 4QABA 5AFKA 2XQAA 3UQ4A 4NPPA 5J5GA 3RI5A 5HEJA 3TLWA 3UU3A 4TNWA 2ZJUA 2ZJVA 3U8KA 5AFHA 4HFHA 3WTLA 5IUXA 4DBMA 3UU4A 3U8MA 4BQTA 2BYSA 4COFA 5J5HA 4A98A 5AFNA 3WTKA 3WTIA 3ZDGA 1UV6A 3JAEA 3WTOA 3UUBA 2XZ6A 4ZK1A 2BJ0A 3U8LA 2XQ8A 2BR8A 5HEHA 4A97A 5HCJA 4ZZCA 2PH9A 4HFBA 2XNVA 4F8HA 4QH1A 2WNJA 2XQ4A 4UM3P 4ZRUA 5AFLA 3JADA 3RIFA 4AFGA 5BRXA 4UM3S 5AFMB 4ALXA 3UU6A 4TWDA 3RHWA 4XHEA 3P50A 2Y7YA 2XZ5A 4HFEA 4IL4A 4X5TA 4ZJTA 5J0ZA 2Y57A 5L47A 2BYPA 2WNLA 2W8GA 2XQ5A 2VL0A 4Z91A 5KE4A 2XQ9A 2WZYA 4AFTA 1UW6A 3WTHA 4ILAA 5BW2A 2XYTA 4HQPA 5J5FA 4UM1A 4LMLA 4AFHA 5BP0A 3ZKRA 2UZ6A 2XNUA 2YOEA 4TNVA 4UXUA 4UY2A 4Z90A 3U8JA 3WTJA 5LXBA 4LMKA 3SQ9A 3U8NA 3SQ6A 5L4EA 2Y58A 4ILCA 3EI0A 4IREA 3TLVA 2BG9B 3TLUA 5J5IA 2PGZA 3TLSA 3TLTA 3UQ7A 2YKSA 2QC1B 4QH5A 3UU8A 5CFBA 1I9BA 4EZ1A 2BYNA 3WTMA 2YMDA 2Y56A 4LMJA 4ZK4A 5TVCA 5HCMA 2X00D 3WTNA 5KZUA 3UU5A 3IGQA 3PMZA 2BG9C 2C9TA 2W8FA 3LSVA 5SYOA 3RQUA 4HFCA 2Y54A 4ZZBA 2BYRA 4TWHA 3GUAA 5CO5A 3EAMA 2XNTA 3WIPA 5AFMA 4HFIA 5HEGA 2YN6A 4BFQA 2XQ3A 3P4WA 2BG9E 4ZR6A 5AFJA 3RQWA 4IL9A 3RIAA 4QACA 4WV9A 4UM3A 4QH4A 4ZJSA 5JMEA 4D01A 3ZDHA 3C84A 2XQ7A 4ILBA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 5HEU A;  1UX2 A;  3EHZ A;  2BYQ A;  4PIR A;  2XQ6 A;  4NZB A;  5AIN A;  4TWF A;  3PEO A;  2XYS A;  4B5D A;  4QAA A;  2BR7 A;  2WNC A;  3SIO A;  2YME A;  3C79 A;  4HFD A;  2WN9 A;  3T4M A;  2X00 A;  3JAF A;  5HEO A;  5L4H A;  2BG9 A;  3SH1 A;  4FRR A;  5LG3 A;  4XK9 A;  5FJV A;  4QAB A;  5AFK A;  2XQA A;  3UQ4 A;  4NPP A;  5J5G A;  3RI5 A;  5HEJ A;  3TLW A;  3UU3 A;  4TNW A;  2ZJU A;  2ZJV A;  3U8K A;  5AFH A;  4HFH A;  3WTL A;  5IUX A;  4DBM A;  3UU4 A;  3U8M A;  4BQT A;  2BYS A;  4COF A;  5J5H A;  4A98 A;  5AFN A;  3WTK A;  3WTI A;  3ZDG A;  1UV6 A;  3JAE A;  3WTO A;  3UUB A;  2XZ6 A;  4ZK1 A;  2BJ0 A;  3U8L A;  2XQ8 A;  2BR8 A;  5HEH A;  4A97 A;  5HCJ A;  4ZZC A;  2PH9 A;  4HFB A;  2XNV A;  4F8H A;  4QH1 A;  2WNJ A;  2XQ4 A;  4UM3 P;  4ZRU A;  5AFL A;  3JAD A;  3RIF A;  4AFG A;  5BRX A;  4UM3 S;  5AFM B;  4ALX A;  3UU6 A;  4TWD A;  3RHW A;  4XHE A;  3P50 A;  2Y7Y A;  2XZ5 A;  4HFE A;  4IL4 A;  4X5T A;  4ZJT A;  5J0Z A;  2Y57 A;  5L47 A;  2BYP A;  2WNL A;  2W8G A;  2XQ5 A;  2VL0 A;  4Z91 A;  5KE4 A;  2XQ9 A;  2WZY A;  4AFT A;  1UW6 A;  3WTH A;  4ILA A;  5BW2 A;  2XYT A;  4HQP A;  5J5F A;  4UM1 A;  4LML A;  4AFH A;  5BP0 A;  3ZKR A;  2UZ6 A;  2XNU A;  2YOE A;  4TNV A;  4UXU A;  4UY2 A;  4Z90 A;  3U8J A;  3WTJ A;  5LXB A;  4LMK A;  3SQ9 A;  3U8N A;  3SQ6 A;  5L4E A;  2Y58 A;  4ILC A;  3EI0 A;  4IRE A;  3TLV A;  2BG9 B;  3TLU A;  5J5I A;  2PGZ A;  3TLS A;  3TLT A;  3UQ7 A;  2YKS A;  2QC1 B;  4QH5 A;  3UU8 A;  5CFB A;  1I9B A;  4EZ1 A;  2BYN A;  3WTM A;  2YMD A;  2Y56 A;  4LMJ A;  4ZK4 A;  5TVC A;  5HCM A;  2X00 D;  3WTN A;  5KZU A;  3UU5 A;  3IGQ A;  3PMZ A;  2BG9 C;  2C9T A;  2W8F A;  3LSV A;  5SYO A;  3RQU A;  4HFC A;  2Y54 A;  4ZZB A;  2BYR A;  4TWH A;  3GUA A;  5CO5 A;  3EAM A;  2XNT A;  3WIP A;  5AFM A;  4HFI A;  5HEG A;  2YN6 A;  4BFQ A;  2XQ3 A;  3P4W A;  2BG9 E;  4ZR6 A;  5AFJ A;  3RQW A;  4IL9 A;  3RIA A;  4QAC A;  4WV9 A;  4UM3 A;  4QH4 A;  4ZJS A;  5JME A;  4D01 A;  3ZDH A;  3C84 A;  2XQ7 A;  4ILB A; 
#chains in the Genus database with same CATH topology
 5HEU A;  1UX2 A;  3EHZ A;  2BYQ A;  4PIR A;  2XQ6 A;  4NZB A;  5AIN A;  4TWF A;  3PEO A;  2XYS A;  4B5D A;  4QAA A;  2BR7 A;  2WNC A;  3SIO A;  2YME A;  3C79 A;  4HFD A;  2WN9 A;  3T4M A;  2X00 A;  3JAF A;  5HEO A;  5L4H A;  2BG9 A;  3SH1 A;  4FRR A;  5LG3 A;  4XK9 A;  5FJV A;  4QAB A;  5AFK A;  2XQA A;  3UQ4 A;  4NPP A;  5J5G A;  3RI5 A;  5HEJ A;  3TLW A;  3UU3 A;  4TNW A;  2ZJU A;  2ZJV A;  3U8K A;  5AFH A;  4HFH A;  3WTL A;  5IUX A;  4DBM A;  3UU4 A;  3U8M A;  4BQT A;  2BYS A;  4COF A;  5J5H A;  4A98 A;  5AFN A;  3WTK A;  3WTI A;  3ZDG A;  1UV6 A;  3JAE A;  3WTO A;  3UUB A;  2XZ6 A;  4ZK1 A;  2BJ0 A;  3U8L A;  2XQ8 A;  2BR8 A;  5HEH A;  4A97 A;  5HCJ A;  4ZZC A;  2PH9 A;  4HFB A;  2XNV A;  4F8H A;  4QH1 A;  2WNJ A;  2XQ4 A;  4UM3 P;  4ZRU A;  5AFL A;  3JAD A;  3RIF A;  4AFG A;  5BRX A;  4UM3 S;  5AFM B;  4ALX A;  3UU6 A;  4TWD A;  3RHW A;  4XHE A;  3P50 A;  2Y7Y A;  2XZ5 A;  4HFE A;  4IL4 A;  4X5T A;  4ZJT A;  5J0Z A;  2Y57 A;  5L47 A;  2BYP A;  2WNL A;  2W8G A;  2XQ5 A;  2VL0 A;  4Z91 A;  5KE4 A;  2XQ9 A;  2WZY A;  4AFT A;  1UW6 A;  3WTH A;  4ILA A;  5BW2 A;  2XYT A;  4HQP A;  5J5F A;  4UM1 A;  4LML A;  4AFH A;  5BP0 A;  3ZKR A;  2UZ6 A;  2XNU A;  2YOE A;  4TNV A;  4UXU A;  4UY2 A;  4Z90 A;  3U8J A;  3WTJ A;  5LXB A;  4LMK A;  3SQ9 A;  3U8N A;  3SQ6 A;  5L4E A;  2Y58 A;  4ILC A;  3EI0 A;  4IRE A;  3TLV A;  2BG9 B;  3TLU A;  5J5I A;  2PGZ A;  3TLS A;  3TLT A;  3UQ7 A;  2YKS A;  2QC1 B;  4QH5 A;  3UU8 A;  5CFB A;  1I9B A;  4EZ1 A;  2BYN A;  3WTM A;  2YMD A;  2Y56 A;  4LMJ A;  4ZK4 A;  5TVC A;  5HCM A;  2X00 D;  3WTN A;  5KZU A;  3UU5 A;  3IGQ A;  3PMZ A;  2BG9 C;  2C9T A;  2W8F A;  3LSV A;  5SYO A;  3RQU A;  4HFC A;  2Y54 A;  4ZZB A;  2BYR A;  4TWH A;  3GUA A;  5CO5 A;  3EAM A;  2XNT A;  3WIP A;  5AFM A;  4HFI A;  5HEG A;  2YN6 A;  4BFQ A;  2XQ3 A;  3P4W A;  2BG9 E;  4ZR6 A;  5AFJ A;  3RQW A;  4IL9 A;  3RIA A;  4QAC A;  4WV9 A;  4UM3 A;  4QH4 A;  4ZJS A;  5JME A;  4D01 A;  3ZDH A;  3C84 A;  2XQ7 A;  4ILB A; 
#chains in the Genus database with same CATH homology
 5HEU A;  1UX2 A;  3EHZ A;  2BYQ A;  4PIR A;  2XQ6 A;  4NZB A;  5AIN A;  4TWF A;  3PEO A;  2XYS A;  4B5D A;  4QAA A;  2BR7 A;  2WNC A;  3SIO A;  2YME A;  3C79 A;  4HFD A;  2WN9 A;  3T4M A;  2X00 A;  3JAF A;  5HEO A;  5L4H A;  2BG9 A;  3SH1 A;  4FRR A;  5LG3 A;  4XK9 A;  5FJV A;  4QAB A;  5AFK A;  2XQA A;  3UQ4 A;  4NPP A;  5J5G A;  3RI5 A;  5HEJ A;  3TLW A;  3UU3 A;  4TNW A;  2ZJU A;  2ZJV A;  3U8K A;  5AFH A;  4HFH A;  3WTL A;  5IUX A;  4DBM A;  3UU4 A;  3U8M A;  4BQT A;  2BYS A;  4COF A;  5J5H A;  4A98 A;  5AFN A;  3WTK A;  3WTI A;  3ZDG A;  1UV6 A;  3JAE A;  3WTO A;  3UUB A;  2XZ6 A;  4ZK1 A;  2BJ0 A;  3U8L A;  2XQ8 A;  2BR8 A;  5HEH A;  4A97 A;  5HCJ A;  4ZZC A;  2PH9 A;  4HFB A;  2XNV A;  4F8H A;  4QH1 A;  2WNJ A;  2XQ4 A;  4UM3 P;  4ZRU A;  5AFL A;  3JAD A;  3RIF A;  4AFG A;  5BRX A;  4UM3 S;  5AFM B;  4ALX A;  3UU6 A;  4TWD A;  3RHW A;  4XHE A;  3P50 A;  2Y7Y A;  2XZ5 A;  4HFE A;  4IL4 A;  4X5T A;  4ZJT A;  5J0Z A;  2Y57 A;  5L47 A;  2BYP A;  2WNL A;  2W8G A;  2XQ5 A;  2VL0 A;  4Z91 A;  5KE4 A;  2XQ9 A;  2WZY A;  4AFT A;  1UW6 A;  3WTH A;  4ILA A;  5BW2 A;  2XYT A;  4HQP A;  5J5F A;  4UM1 A;  4LML A;  4AFH A;  5BP0 A;  3ZKR A;  2UZ6 A;  2XNU A;  2YOE A;  4TNV A;  4UXU A;  4UY2 A;  4Z90 A;  3U8J A;  3WTJ A;  5LXB A;  4LMK A;  3SQ9 A;  3U8N A;  3SQ6 A;  5L4E A;  2Y58 A;  4ILC A;  3EI0 A;  4IRE A;  3TLV A;  2BG9 B;  3TLU A;  5J5I A;  2PGZ A;  3TLS A;  3TLT A;  3UQ7 A;  2YKS A;  2QC1 B;  4QH5 A;  3UU8 A;  5CFB A;  1I9B A;  4EZ1 A;  2BYN A;  3WTM A;  2YMD A;  2Y56 A;  4LMJ A;  4ZK4 A;  5TVC A;  5HCM A;  2X00 D;  3WTN A;  5KZU A;  3UU5 A;  3IGQ A;  3PMZ A;  2BG9 C;  2C9T A;  2W8F A;  3LSV A;  5SYO A;  3RQU A;  4HFC A;  2Y54 A;  4ZZB A;  2BYR A;  4TWH A;  3GUA A;  5CO5 A;  3EAM A;  2XNT A;  3WIP A;  5AFM A;  4HFI A;  5HEG A;  2YN6 A;  4BFQ A;  2XQ3 A;  3P4W A;  2BG9 E;  4ZR6 A;  5AFJ A;  3RQW A;  4IL9 A;  3RIA A;  4QAC A;  4WV9 A;  4UM3 A;  4QH4 A;  4ZJS A;  5JME A;  4D01 A;  3ZDH A;  3C84 A;  2XQ7 A;  4ILB A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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5BRXA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations