5FJV | Genus

Total Genus 35

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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	35
sequence length	206
structure length	206
Chain Sequence	DRLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEFAVTHMTKAHLFSTGTVHWVPPAIYKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAIVNATGTYNSKKYDCCAEIYPDVTYAFVIRRLP

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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Acetylcholine-binding protein
source organism	Homo sapiens
publication title	Crystal Structure of a Human Neuronal Nachr Extracellular Domain in Pentameric Assembly: Ligand-Bound Alpah2 Homopentamer. pubmed doi rcsb
molecule keywords	NEURONAL ACETYLCHOLINE RECEPTOR SUBUNIT ALPHA-2
total genus	35
structure length	206
sequence length	206
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2015-10-13

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	5fjvA00

3GUAA 4IREA 4Z91A 5AFKA 2WN9A 4ZZCA 5HEGA 3ZDHA 1I9BA 4LMKA 4QH5A 2WNJA 4TWDA 2BG9A 3SH1A 3P50A 4TWHA 2YKSA 4D01A 3TLTA 4QAAA 2ZJVA 4UM3S 4TNWA 4WV9A 2WZYA 5AFHA 4ALXA 4UM3P 5BP0A 4HFIA 5HCMA 2ZJUA 2XQ3A 3TLUA 3PMZA 2Y7YA 4HFHA 5J5FA 5J0ZA 5HEJA 3U8JA 2BR7A 2XQ6A 5TVCA 3JADA 2XZ5A 2BYNA 2Y58A 3RQWA 3U8KA 4QH4A 3UU6A 2YMDA 2WNCA 2XQ8A 3TLSA 5AFJA 3JAFA 4TWFA 2BYSA 2XNVA 5J5IA 3WTIA 3WTMA 4HQPA 5CFBA 5L4HA 5BW2A 4X5TA 3SQ6A 4NZBA 3WTLA 2BG9E 4PIRA 3RQUA 3WTHA 2XQ9A 4NPPA 5AFMB 2PGZA 3TLWA 3WTKA 4XK9A 5AFLA 5LXBA 4Z90A 4A98A 5J5GA 5SYOA 3UQ4A 4UY2A 4ZK4A 2YN6A 3JAEA 3U8LA 3T4MA 2BR8A 2BG9B 4HFBA 2Y54A 4QABA 5JMEA 2W8FA 4BFQA 4AFHA 5HCJA 4AFTA 2XYTA 2Y56A 5KZUA 2XQ7A 3P4WA 5HEUA 3UU4A 4B5DA 3ZKRA 2BYQA 4EZ1A 4ILAA 5HEHA 3WTJA 2Y57A 3UQ7A 4AFGA 4HFCA 5HEOA 5L4EA 2UZ6A 3EAMA 3UU5A 3U8NA 4TNVA 3PEOA 4ZZBA 3RIAA 4HFDA 1UV6A 2C9TA 4UM3A 4UXUA 2W8GA 4LMLA 3UU8A 3WTOA 2BJ0A 2X00A 5L47A 5LG3A 3C84A 2X00D 4IL4A 3IGQA 3RIFA 2PH9A 3ZDGA 5AFMA 3EI0A 4COFA 4ILBA 3RI5A 2XYSA 2XQ4A 2YOEA 4ZJSA 2XZ6A 3LSVA 5IUXA 2XNTA 5CO5A 2BG9C 3UUBA 2BYPA 2YMEA 3UU3A 1UX2A 4XHEA 4UM1A 3WIPA 5AINA 4ZR6A 4ZK1A 4HFEA 4QACA 3SQ9A 2BYRA 4FRRA 5AFNA 3U8MA 2XQAA 3TLVA 2XNUA 2WNLA 4ILCA 4LMJA 3EHZA 5KE4A 4QH1A 4ZJTA 2QC1B 3C79A 4ZRUA 4DBMA 1UW6A 4BQTA 4A97A 4IL9A 3SIOA 5BRXA 2XQ5A 4F8HA 5FJVA 5J5HA 2VL0A 3RHWA 3WTNA
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 3GUA A;  4IRE A;  4Z91 A;  5AFK A;  2WN9 A;  4ZZC A;  5HEG A;  3ZDH A;  1I9B A;  4LMK A;  4QH5 A;  2WNJ A;  4TWD A;  2BG9 A;  3SH1 A;  3P50 A;  4TWH A;  2YKS A;  4D01 A;  3TLT A;  4QAA A;  2ZJV A;  4UM3 S;  4TNW A;  4WV9 A;  2WZY A;  5AFH A;  4ALX A;  4UM3 P;  5BP0 A;  4HFI A;  5HCM A;  2ZJU A;  2XQ3 A;  3TLU A;  3PMZ A;  2Y7Y A;  4HFH A;  5J5F A;  5J0Z A;  5HEJ A;  3U8J A;  2BR7 A;  2XQ6 A;  5TVC A;  3JAD A;  2XZ5 A;  2BYN A;  2Y58 A;  3RQW A;  3U8K A;  4QH4 A;  3UU6 A;  2YMD A;  2WNC A;  2XQ8 A;  3TLS A;  5AFJ A;  3JAF A;  4TWF A;  2BYS A;  2XNV A;  5J5I A;  3WTI A;  3WTM A;  4HQP A;  5CFB A;  5L4H A;  5BW2 A;  4X5T A;  3SQ6 A;  4NZB A;  3WTL A;  2BG9 E;  4PIR A;  3RQU A;  3WTH A;  2XQ9 A;  4NPP A;  5AFM B;  2PGZ A;  3TLW A;  3WTK A;  4XK9 A;  5AFL A;  5LXB A;  4Z90 A;  4A98 A;  5J5G A;  5SYO A;  3UQ4 A;  4UY2 A;  4ZK4 A;  2YN6 A;  3JAE A;  3U8L A;  3T4M A;  2BR8 A;  2BG9 B;  4HFB A;  2Y54 A;  4QAB A;  5JME A;  2W8F A;  4BFQ A;  4AFH A;  5HCJ A;  4AFT A;  2XYT A;  2Y56 A;  5KZU A;  2XQ7 A;  3P4W A;  5HEU A;  3UU4 A;  4B5D A;  3ZKR A;  2BYQ A;  4EZ1 A;  4ILA A;  5HEH A;  3WTJ A;  2Y57 A;  3UQ7 A;  4AFG A;  4HFC A;  5HEO A;  5L4E A;  2UZ6 A;  3EAM A;  3UU5 A;  3U8N A;  4TNV A;  3PEO A;  4ZZB A;  3RIA A;  4HFD A;  1UV6 A;  2C9T A;  4UM3 A;  4UXU A;  2W8G A;  4LML A;  3UU8 A;  3WTO A;  2BJ0 A;  2X00 A;  5L47 A;  5LG3 A;  3C84 A;  2X00 D;  4IL4 A;  3IGQ A;  3RIF A;  2PH9 A;  3ZDG A;  5AFM A;  3EI0 A;  4COF A;  4ILB A;  3RI5 A;  2XYS A;  2XQ4 A;  2YOE A;  4ZJS A;  2XZ6 A;  3LSV A;  5IUX A;  2XNT A;  5CO5 A;  2BG9 C;  3UUB A;  2BYP A;  2YME A;  3UU3 A;  1UX2 A;  4XHE A;  4UM1 A;  3WIP A;  5AIN A;  4ZR6 A;  4ZK1 A;  4HFE A;  4QAC A;  3SQ9 A;  2BYR A;  4FRR A;  5AFN A;  3U8M A;  2XQA A;  3TLV A;  2XNU A;  2WNL A;  4ILC A;  4LMJ A;  3EHZ A;  5KE4 A;  4QH1 A;  4ZJT A;  2QC1 B;  3C79 A;  4ZRU A;  4DBM A;  1UW6 A;  4BQT A;  4A97 A;  4IL9 A;  3SIO A;  5BRX A;  2XQ5 A;  4F8H A;  5FJV A;  5J5H A;  2VL0 A;  3RHW A;  3WTN A; 
#chains in the Genus database with same CATH topology
 3GUA A;  4IRE A;  4Z91 A;  5AFK A;  2WN9 A;  4ZZC A;  5HEG A;  3ZDH A;  1I9B A;  4LMK A;  4QH5 A;  2WNJ A;  4TWD A;  2BG9 A;  3SH1 A;  3P50 A;  4TWH A;  2YKS A;  4D01 A;  3TLT A;  4QAA A;  2ZJV A;  4UM3 S;  4TNW A;  4WV9 A;  2WZY A;  5AFH A;  4ALX A;  4UM3 P;  5BP0 A;  4HFI A;  5HCM A;  2ZJU A;  2XQ3 A;  3TLU A;  3PMZ A;  2Y7Y A;  4HFH A;  5J5F A;  5J0Z A;  5HEJ A;  3U8J A;  2BR7 A;  2XQ6 A;  5TVC A;  3JAD A;  2XZ5 A;  2BYN A;  2Y58 A;  3RQW A;  3U8K A;  4QH4 A;  3UU6 A;  2YMD A;  2WNC A;  2XQ8 A;  3TLS A;  5AFJ A;  3JAF A;  4TWF A;  2BYS A;  2XNV A;  5J5I A;  3WTI A;  3WTM A;  4HQP A;  5CFB A;  5L4H A;  5BW2 A;  4X5T A;  3SQ6 A;  4NZB A;  3WTL A;  2BG9 E;  4PIR A;  3RQU A;  3WTH A;  2XQ9 A;  4NPP A;  5AFM B;  2PGZ A;  3TLW A;  3WTK A;  4XK9 A;  5AFL A;  5LXB A;  4Z90 A;  4A98 A;  5J5G A;  5SYO A;  3UQ4 A;  4UY2 A;  4ZK4 A;  2YN6 A;  3JAE A;  3U8L A;  3T4M A;  2BR8 A;  2BG9 B;  4HFB A;  2Y54 A;  4QAB A;  5JME A;  2W8F A;  4BFQ A;  4AFH A;  5HCJ A;  4AFT A;  2XYT A;  2Y56 A;  5KZU A;  2XQ7 A;  3P4W A;  5HEU A;  3UU4 A;  4B5D A;  3ZKR A;  2BYQ A;  4EZ1 A;  4ILA A;  5HEH A;  3WTJ A;  2Y57 A;  3UQ7 A;  4AFG A;  4HFC A;  5HEO A;  5L4E A;  2UZ6 A;  3EAM A;  3UU5 A;  3U8N A;  4TNV A;  3PEO A;  4ZZB A;  3RIA A;  4HFD A;  1UV6 A;  2C9T A;  4UM3 A;  4UXU A;  2W8G A;  4LML A;  3UU8 A;  3WTO A;  2BJ0 A;  2X00 A;  5L47 A;  5LG3 A;  3C84 A;  2X00 D;  4IL4 A;  3IGQ A;  3RIF A;  2PH9 A;  3ZDG A;  5AFM A;  3EI0 A;  4COF A;  4ILB A;  3RI5 A;  2XYS A;  2XQ4 A;  2YOE A;  4ZJS A;  2XZ6 A;  3LSV A;  5IUX A;  2XNT A;  5CO5 A;  2BG9 C;  3UUB A;  2BYP A;  2YME A;  3UU3 A;  1UX2 A;  4XHE A;  4UM1 A;  3WIP A;  5AIN A;  4ZR6 A;  4ZK1 A;  4HFE A;  4QAC A;  3SQ9 A;  2BYR A;  4FRR A;  5AFN A;  3U8M A;  2XQA A;  3TLV A;  2XNU A;  2WNL A;  4ILC A;  4LMJ A;  3EHZ A;  5KE4 A;  4QH1 A;  4ZJT A;  2QC1 B;  3C79 A;  4ZRU A;  4DBM A;  1UW6 A;  4BQT A;  4A97 A;  4IL9 A;  3SIO A;  5BRX A;  2XQ5 A;  4F8H A;  5FJV A;  5J5H A;  2VL0 A;  3RHW A;  3WTN A; 
#chains in the Genus database with same CATH homology
 3GUA A;  4IRE A;  4Z91 A;  5AFK A;  2WN9 A;  4ZZC A;  5HEG A;  3ZDH A;  1I9B A;  4LMK A;  4QH5 A;  2WNJ A;  4TWD A;  2BG9 A;  3SH1 A;  3P50 A;  4TWH A;  2YKS A;  4D01 A;  3TLT A;  4QAA A;  2ZJV A;  4UM3 S;  4TNW A;  4WV9 A;  2WZY A;  5AFH A;  4ALX A;  4UM3 P;  5BP0 A;  4HFI A;  5HCM A;  2ZJU A;  2XQ3 A;  3TLU A;  3PMZ A;  2Y7Y A;  4HFH A;  5J5F A;  5J0Z A;  5HEJ A;  3U8J A;  2BR7 A;  2XQ6 A;  5TVC A;  3JAD A;  2XZ5 A;  2BYN A;  2Y58 A;  3RQW A;  3U8K A;  4QH4 A;  3UU6 A;  2YMD A;  2WNC A;  2XQ8 A;  3TLS A;  5AFJ A;  3JAF A;  4TWF A;  2BYS A;  2XNV A;  5J5I A;  3WTI A;  3WTM A;  4HQP A;  5CFB A;  5L4H A;  5BW2 A;  4X5T A;  3SQ6 A;  4NZB A;  3WTL A;  2BG9 E;  4PIR A;  3RQU A;  3WTH A;  2XQ9 A;  4NPP A;  5AFM B;  2PGZ A;  3TLW A;  3WTK A;  4XK9 A;  5AFL A;  5LXB A;  4Z90 A;  4A98 A;  5J5G A;  5SYO A;  3UQ4 A;  4UY2 A;  4ZK4 A;  2YN6 A;  3JAE A;  3U8L A;  3T4M A;  2BR8 A;  2BG9 B;  4HFB A;  2Y54 A;  4QAB A;  5JME A;  2W8F A;  4BFQ A;  4AFH A;  5HCJ A;  4AFT A;  2XYT A;  2Y56 A;  5KZU A;  2XQ7 A;  3P4W A;  5HEU A;  3UU4 A;  4B5D A;  3ZKR A;  2BYQ A;  4EZ1 A;  4ILA A;  5HEH A;  3WTJ A;  2Y57 A;  3UQ7 A;  4AFG A;  4HFC A;  5HEO A;  5L4E A;  2UZ6 A;  3EAM A;  3UU5 A;  3U8N A;  4TNV A;  3PEO A;  4ZZB A;  3RIA A;  4HFD A;  1UV6 A;  2C9T A;  4UM3 A;  4UXU A;  2W8G A;  4LML A;  3UU8 A;  3WTO A;  2BJ0 A;  2X00 A;  5L47 A;  5LG3 A;  3C84 A;  2X00 D;  4IL4 A;  3IGQ A;  3RIF A;  2PH9 A;  3ZDG A;  5AFM A;  3EI0 A;  4COF A;  4ILB A;  3RI5 A;  2XYS A;  2XQ4 A;  2YOE A;  4ZJS A;  2XZ6 A;  3LSV A;  5IUX A;  2XNT A;  5CO5 A;  2BG9 C;  3UUB A;  2BYP A;  2YME A;  3UU3 A;  1UX2 A;  4XHE A;  4UM1 A;  3WIP A;  5AIN A;  4ZR6 A;  4ZK1 A;  4HFE A;  4QAC A;  3SQ9 A;  2BYR A;  4FRR A;  5AFN A;  3U8M A;  2XQA A;  3TLV A;  2XNU A;  2WNL A;  4ILC A;  4LMJ A;  3EHZ A;  5KE4 A;  4QH1 A;  4ZJT A;  2QC1 B;  3C79 A;  4ZRU A;  4DBM A;  1UW6 A;  4BQT A;  4A97 A;  4IL9 A;  3SIO A;  5BRX A;  2XQ5 A;  4F8H A;  5FJV A;  5J5H A;  2VL0 A;  3RHW A;  3WTN A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

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#similar chains, but unknotted
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5FJVA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations