5KZUA

Crystal structure of an acetylcholine binding protein from aplysia californica (ac-achbp) in complex with click chemistry compound 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole
Total Genus 49
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
208
structure length
207
Chain Sequence
KLHSQANLMRLKSDLFNRPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) in complex with click chemistry compound 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole
rcsb
molecule tags Acetylcholine-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 49
structure length 207
sequence length 208
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2016-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 5kzuA00
3PMZA 5HEOA 3SQ9A 3WTMA 3WTKA 2WN9A 5L47A 2BR8A 3TLSA 3SQ6A 5L4EA 3EHZA 4QH4A 3WTHA 4QH5A 4UXUA 4UM3P 3TLWA 3GUAA 4BQTA 2BYPA 2BJ0A 3WIPA 4NPPA 2YOEA 2WNJA 3UQ7A 2XNVA 3P50A 5LG3A 2BYQA 4HFIA 4TWFA 5IUXA 4ILAA 3TLUA 3U8JA 2Y7YA 5L4HA 3JADA 2UZ6A 4AFHA 3ZDHA 5AFMB 5AFMA 4QAAA 2Y54A 2XQ9A 2XYTA 3C79A 2WZYA 2XQ6A 4TNVA 3UUBA 5LXBA 3JAFA 1UW6A 4ZK4A 3UU3A 4COFA 4LMJA 1UX2A 2BR7A 3TLVA 2WNLA 4IREA 3JAEA 4AFGA 4QH1A 2W8FA 2XZ5A 2Y58A 5J5FA 5BRXA 3PEOA 4D01A 3U8MA 2ZJVA 4HFHA 4Z90A 4ZRUA 5AFNA 4HFDA 4IL4A 4ILCA 3RHWA 2YN6A 2YMDA 2WNCA 4UM1A 4B5DA 2YKSA 3ZKRA 5AINA 3U8NA 5J5GA 2BYSA 4ALXA 4IL9A 4ZJSA 2XNTA 4LMLA 4ZZCA 3WTNA 2W8GA 4HFEA 2BYNA 5HEHA 5KZUA 5AFHA 2QC1B 3RIAA 3U8LA 4UM3S 2PGZA 4AFTA 4TWDA 4UM3A 5KE4A 2BYRA 4ZK1A 3SIOA 1UV6A 3LSVA 5J5IA 4QACA 4NZBA 5SYOA 3UU4A 2Y56A 2BG9C 2Y57A 3ZDGA 2XZ6A 5AFKA 4UY2A 4TWHA 4HQPA 4WV9A 5AFLA 3WTIA 3RQUA 2BG9B 3WTLA 4ZJTA 3EAMA 3IGQA 3EI0A 3UU5A 2XNUA 4Z91A 4ZR6A 3UU6A 4F8HA 2YMEA 2XQ5A 3P4WA 2XQAA 2XQ8A 4LMKA 4TNWA 4QABA 5AFJA 3T4MA 4ILBA 2C9TA 5HEJA 2X00A 4BFQA 4XK9A 2PH9A 1I9BA 5CO5A 2ZJUA 5BP0A 4XHEA 5FJVA 5CFBA 5HCJA 3RI5A 4PIRA 2X00D 2BG9E 3SH1A 3WTOA 3U8KA 4DBMA 5BW2A 2XYSA 3C84A 3WTJA 2VL0A 3TLTA 3UU8A 3UQ4A 4X5TA 4ZZBA 5HEGA 4HFCA 5TVCA 4EZ1A 2BG9A 4A98A 5J5HA 2XQ4A 3RIFA 5HCMA 4A97A 3RQWA 4HFBA 5JMEA 2XQ7A 5HEUA 5J0ZA 2XQ3A 4FRRA
chains in the Genus database with same CATH superfamily
3PMZA 5HEOA 3SQ9A 3WTMA 3WTKA 2WN9A 5L47A 2BR8A 3TLSA 3SQ6A 5L4EA 3EHZA 4QH4A 3WTHA 4QH5A 4UXUA 4UM3P 3TLWA 3GUAA 4BQTA 2BYPA 2BJ0A 3WIPA 4NPPA 2YOEA 2WNJA 3UQ7A 2XNVA 3P50A 5LG3A 2BYQA 4HFIA 4TWFA 5IUXA 4ILAA 3TLUA 3U8JA 2Y7YA 5L4HA 3JADA 2UZ6A 4AFHA 3ZDHA 5AFMB 5AFMA 4QAAA 2Y54A 2XQ9A 2XYTA 3C79A 2WZYA 2XQ6A 4TNVA 3UUBA 5LXBA 3JAFA 1UW6A 4ZK4A 3UU3A 4COFA 4LMJA 1UX2A 2BR7A 3TLVA 2WNLA 4IREA 3JAEA 4AFGA 4QH1A 2W8FA 2XZ5A 2Y58A 5J5FA 5BRXA 3PEOA 4D01A 3U8MA 2ZJVA 4HFHA 4Z90A 4ZRUA 5AFNA 4HFDA 4IL4A 4ILCA 3RHWA 2YN6A 2YMDA 2WNCA 4UM1A 4B5DA 2YKSA 3ZKRA 5AINA 3U8NA 5J5GA 2BYSA 4ALXA 4IL9A 4ZJSA 2XNTA 4LMLA 4ZZCA 3WTNA 2W8GA 4HFEA 2BYNA 5HEHA 5KZUA 5AFHA 2QC1B 3RIAA 3U8LA 4UM3S 2PGZA 4AFTA 4TWDA 4UM3A 5KE4A 2BYRA 4ZK1A 3SIOA 1UV6A 3LSVA 5J5IA 4QACA 4NZBA 5SYOA 3UU4A 2Y56A 2BG9C 2Y57A 3ZDGA 2XZ6A 5AFKA 4UY2A 4TWHA 4HQPA 4WV9A 5AFLA 3WTIA 3RQUA 2BG9B 3WTLA 4ZJTA 3EAMA 3IGQA 3EI0A 3UU5A 2XNUA 4Z91A 4ZR6A 3UU6A 4F8HA 2YMEA 2XQ5A 3P4WA 2XQAA 2XQ8A 4LMKA 4TNWA 4QABA 5AFJA 3T4MA 4ILBA 2C9TA 5HEJA 2X00A 4BFQA 4XK9A 2PH9A 1I9BA 5CO5A 2ZJUA 5BP0A 4XHEA 5FJVA 5CFBA 5HCJA 3RI5A 4PIRA 2X00D 2BG9E 3SH1A 3WTOA 3U8KA 4DBMA 5BW2A 2XYSA 3C84A 3WTJA 2VL0A 3TLTA 3UU8A 3UQ4A 4X5TA 4ZZBA 5HEGA 4HFCA 5TVCA 4EZ1A 2BG9A 4A98A 5J5HA 2XQ4A 3RIFA 5HCMA 4A97A 3RQWA 4HFBA 5JMEA 2XQ7A 5HEUA 5J0ZA 2XQ3A 4FRRA
chains in the Genus database with same CATH topology
3PMZA 5HEOA 3SQ9A 3WTMA 3WTKA 2WN9A 5L47A 2BR8A 3TLSA 3SQ6A 5L4EA 3EHZA 4QH4A 3WTHA 4QH5A 4UXUA 4UM3P 3TLWA 3GUAA 4BQTA 2BYPA 2BJ0A 3WIPA 4NPPA 2YOEA 2WNJA 3UQ7A 2XNVA 3P50A 5LG3A 2BYQA 4HFIA 4TWFA 5IUXA 4ILAA 3TLUA 3U8JA 2Y7YA 5L4HA 3JADA 2UZ6A 4AFHA 3ZDHA 5AFMB 5AFMA 4QAAA 2Y54A 2XQ9A 2XYTA 3C79A 2WZYA 2XQ6A 4TNVA 3UUBA 5LXBA 3JAFA 1UW6A 4ZK4A 3UU3A 4COFA 4LMJA 1UX2A 2BR7A 3TLVA 2WNLA 4IREA 3JAEA 4AFGA 4QH1A 2W8FA 2XZ5A 2Y58A 5J5FA 5BRXA 3PEOA 4D01A 3U8MA 2ZJVA 4HFHA 4Z90A 4ZRUA 5AFNA 4HFDA 4IL4A 4ILCA 3RHWA 2YN6A 2YMDA 2WNCA 4UM1A 4B5DA 2YKSA 3ZKRA 5AINA 3U8NA 5J5GA 2BYSA 4ALXA 4IL9A 4ZJSA 2XNTA 4LMLA 4ZZCA 3WTNA 2W8GA 4HFEA 2BYNA 5HEHA 5KZUA 5AFHA 2QC1B 3RIAA 3U8LA 4UM3S 2PGZA 4AFTA 4TWDA 4UM3A 5KE4A 2BYRA 4ZK1A 3SIOA 1UV6A 3LSVA 5J5IA 4QACA 4NZBA 5SYOA 3UU4A 2Y56A 2BG9C 2Y57A 3ZDGA 2XZ6A 5AFKA 4UY2A 4TWHA 4HQPA 4WV9A 5AFLA 3WTIA 3RQUA 2BG9B 3WTLA 4ZJTA 3EAMA 3IGQA 3EI0A 3UU5A 2XNUA 4Z91A 4ZR6A 3UU6A 4F8HA 2YMEA 2XQ5A 3P4WA 2XQAA 2XQ8A 4LMKA 4TNWA 4QABA 5AFJA 3T4MA 4ILBA 2C9TA 5HEJA 2X00A 4BFQA 4XK9A 2PH9A 1I9BA 5CO5A 2ZJUA 5BP0A 4XHEA 5FJVA 5CFBA 5HCJA 3RI5A 4PIRA 2X00D 2BG9E 3SH1A 3WTOA 3U8KA 4DBMA 5BW2A 2XYSA 3C84A 3WTJA 2VL0A 3TLTA 3UU8A 3UQ4A 4X5TA 4ZZBA 5HEGA 4HFCA 5TVCA 4EZ1A 2BG9A 4A98A 5J5HA 2XQ4A 3RIFA 5HCMA 4A97A 3RQWA 4HFBA 5JMEA 2XQ7A 5HEUA 5J0ZA 2XQ3A 4FRRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PMZ A;  5HEO A;  3SQ9 A;  3WTM A;  3WTK A;  2WN9 A;  5L47 A;  2BR8 A;  3TLS A;  3SQ6 A;  5L4E A;  3EHZ A;  4QH4 A;  3WTH A;  4QH5 A;  4UXU A;  4UM3 P;  3TLW A;  3GUA A;  4BQT A;  2BYP A;  2BJ0 A;  3WIP A;  4NPP A;  2YOE A;  2WNJ A;  3UQ7 A;  2XNV A;  3P50 A;  5LG3 A;  2BYQ A;  4HFI A;  4TWF A;  5IUX A;  4ILA A;  3TLU A;  3U8J A;  2Y7Y A;  5L4H A;  3JAD A;  2UZ6 A;  4AFH A;  3ZDH A;  5AFM B;  5AFM A;  4QAA A;  2Y54 A;  2XQ9 A;  2XYT A;  3C79 A;  2WZY A;  2XQ6 A;  4TNV A;  3UUB A;  5LXB A;  3JAF A;  1UW6 A;  4ZK4 A;  3UU3 A;  4COF A;  4LMJ A;  1UX2 A;  2BR7 A;  3TLV A;  2WNL A;  4IRE A;  3JAE A;  4AFG A;  4QH1 A;  2W8F A;  2XZ5 A;  2Y58 A;  5J5F A;  5BRX A;  3PEO A;  4D01 A;  3U8M A;  2ZJV A;  4HFH A;  4Z90 A;  4ZRU A;  5AFN A;  4HFD A;  4IL4 A;  4ILC A;  3RHW A;  2YN6 A;  2YMD A;  2WNC A;  4UM1 A;  4B5D A;  2YKS A;  3ZKR A;  5AIN A;  3U8N A;  5J5G A;  2BYS A;  4ALX A;  4IL9 A;  4ZJS A;  2XNT A;  4LML A;  4ZZC A;  3WTN A;  2W8G A;  4HFE A;  2BYN A;  5HEH A;  5KZU A;  5AFH A;  2QC1 B;  3RIA A;  3U8L A;  4UM3 S;  2PGZ A;  4AFT A;  4TWD A;  4UM3 A;  5KE4 A;  2BYR A;  4ZK1 A;  3SIO A;  1UV6 A;  3LSV A;  5J5I A;  4QAC A;  4NZB A;  5SYO A;  3UU4 A;  2Y56 A;  2BG9 C;  2Y57 A;  3ZDG A;  2XZ6 A;  5AFK A;  4UY2 A;  4TWH A;  4HQP A;  4WV9 A;  5AFL A;  3WTI A;  3RQU A;  2BG9 B;  3WTL A;  4ZJT A;  3EAM A;  3IGQ A;  3EI0 A;  3UU5 A;  2XNU A;  4Z91 A;  4ZR6 A;  3UU6 A;  4F8H A;  2YME A;  2XQ5 A;  3P4W A;  2XQA A;  2XQ8 A;  4LMK A;  4TNW A;  4QAB A;  5AFJ A;  3T4M A;  4ILB A;  2C9T A;  5HEJ A;  2X00 A;  4BFQ A;  4XK9 A;  2PH9 A;  1I9B A;  5CO5 A;  2ZJU A;  5BP0 A;  4XHE A;  5FJV A;  5CFB A;  5HCJ A;  3RI5 A;  4PIR A;  2X00 D;  2BG9 E;  3SH1 A;  3WTO A;  3U8K A;  4DBM A;  5BW2 A;  2XYS A;  3C84 A;  3WTJ A;  2VL0 A;  3TLT A;  3UU8 A;  3UQ4 A;  4X5T A;  4ZZB A;  5HEG A;  4HFC A;  5TVC A;  4EZ1 A;  2BG9 A;  4A98 A;  5J5H A;  2XQ4 A;  3RIF A;  5HCM A;  4A97 A;  3RQW A;  4HFB A;  5JME A;  2XQ7 A;  5HEU A;  5J0Z A;  2XQ3 A;  4FRR A; 
#chains in the Genus database with same CATH topology
 3PMZ A;  5HEO A;  3SQ9 A;  3WTM A;  3WTK A;  2WN9 A;  5L47 A;  2BR8 A;  3TLS A;  3SQ6 A;  5L4E A;  3EHZ A;  4QH4 A;  3WTH A;  4QH5 A;  4UXU A;  4UM3 P;  3TLW A;  3GUA A;  4BQT A;  2BYP A;  2BJ0 A;  3WIP A;  4NPP A;  2YOE A;  2WNJ A;  3UQ7 A;  2XNV A;  3P50 A;  5LG3 A;  2BYQ A;  4HFI A;  4TWF A;  5IUX A;  4ILA A;  3TLU A;  3U8J A;  2Y7Y A;  5L4H A;  3JAD A;  2UZ6 A;  4AFH A;  3ZDH A;  5AFM B;  5AFM A;  4QAA A;  2Y54 A;  2XQ9 A;  2XYT A;  3C79 A;  2WZY A;  2XQ6 A;  4TNV A;  3UUB A;  5LXB A;  3JAF A;  1UW6 A;  4ZK4 A;  3UU3 A;  4COF A;  4LMJ A;  1UX2 A;  2BR7 A;  3TLV A;  2WNL A;  4IRE A;  3JAE A;  4AFG A;  4QH1 A;  2W8F A;  2XZ5 A;  2Y58 A;  5J5F A;  5BRX A;  3PEO A;  4D01 A;  3U8M A;  2ZJV A;  4HFH A;  4Z90 A;  4ZRU A;  5AFN A;  4HFD A;  4IL4 A;  4ILC A;  3RHW A;  2YN6 A;  2YMD A;  2WNC A;  4UM1 A;  4B5D A;  2YKS A;  3ZKR A;  5AIN A;  3U8N A;  5J5G A;  2BYS A;  4ALX A;  4IL9 A;  4ZJS A;  2XNT A;  4LML A;  4ZZC A;  3WTN A;  2W8G A;  4HFE A;  2BYN A;  5HEH A;  5KZU A;  5AFH A;  2QC1 B;  3RIA A;  3U8L A;  4UM3 S;  2PGZ A;  4AFT A;  4TWD A;  4UM3 A;  5KE4 A;  2BYR A;  4ZK1 A;  3SIO A;  1UV6 A;  3LSV A;  5J5I A;  4QAC A;  4NZB A;  5SYO A;  3UU4 A;  2Y56 A;  2BG9 C;  2Y57 A;  3ZDG A;  2XZ6 A;  5AFK A;  4UY2 A;  4TWH A;  4HQP A;  4WV9 A;  5AFL A;  3WTI A;  3RQU A;  2BG9 B;  3WTL A;  4ZJT A;  3EAM A;  3IGQ A;  3EI0 A;  3UU5 A;  2XNU A;  4Z91 A;  4ZR6 A;  3UU6 A;  4F8H A;  2YME A;  2XQ5 A;  3P4W A;  2XQA A;  2XQ8 A;  4LMK A;  4TNW A;  4QAB A;  5AFJ A;  3T4M A;  4ILB A;  2C9T A;  5HEJ A;  2X00 A;  4BFQ A;  4XK9 A;  2PH9 A;  1I9B A;  5CO5 A;  2ZJU A;  5BP0 A;  4XHE A;  5FJV A;  5CFB A;  5HCJ A;  3RI5 A;  4PIR A;  2X00 D;  2BG9 E;  3SH1 A;  3WTO A;  3U8K A;  4DBM A;  5BW2 A;  2XYS A;  3C84 A;  3WTJ A;  2VL0 A;  3TLT A;  3UU8 A;  3UQ4 A;  4X5T A;  4ZZB A;  5HEG A;  4HFC A;  5TVC A;  4EZ1 A;  2BG9 A;  4A98 A;  5J5H A;  2XQ4 A;  3RIF A;  5HCM A;  4A97 A;  3RQW A;  4HFB A;  5JME A;  2XQ7 A;  5HEU A;  5J0Z A;  2XQ3 A;  4FRR A; 
#chains in the Genus database with same CATH homology
 3PMZ A;  5HEO A;  3SQ9 A;  3WTM A;  3WTK A;  2WN9 A;  5L47 A;  2BR8 A;  3TLS A;  3SQ6 A;  5L4E A;  3EHZ A;  4QH4 A;  3WTH A;  4QH5 A;  4UXU A;  4UM3 P;  3TLW A;  3GUA A;  4BQT A;  2BYP A;  2BJ0 A;  3WIP A;  4NPP A;  2YOE A;  2WNJ A;  3UQ7 A;  2XNV A;  3P50 A;  5LG3 A;  2BYQ A;  4HFI A;  4TWF A;  5IUX A;  4ILA A;  3TLU A;  3U8J A;  2Y7Y A;  5L4H A;  3JAD A;  2UZ6 A;  4AFH A;  3ZDH A;  5AFM B;  5AFM A;  4QAA A;  2Y54 A;  2XQ9 A;  2XYT A;  3C79 A;  2WZY A;  2XQ6 A;  4TNV A;  3UUB A;  5LXB A;  3JAF A;  1UW6 A;  4ZK4 A;  3UU3 A;  4COF A;  4LMJ A;  1UX2 A;  2BR7 A;  3TLV A;  2WNL A;  4IRE A;  3JAE A;  4AFG A;  4QH1 A;  2W8F A;  2XZ5 A;  2Y58 A;  5J5F A;  5BRX A;  3PEO A;  4D01 A;  3U8M A;  2ZJV A;  4HFH A;  4Z90 A;  4ZRU A;  5AFN A;  4HFD A;  4IL4 A;  4ILC A;  3RHW A;  2YN6 A;  2YMD A;  2WNC A;  4UM1 A;  4B5D A;  2YKS A;  3ZKR A;  5AIN A;  3U8N A;  5J5G A;  2BYS A;  4ALX A;  4IL9 A;  4ZJS A;  2XNT A;  4LML A;  4ZZC A;  3WTN A;  2W8G A;  4HFE A;  2BYN A;  5HEH A;  5KZU A;  5AFH A;  2QC1 B;  3RIA A;  3U8L A;  4UM3 S;  2PGZ A;  4AFT A;  4TWD A;  4UM3 A;  5KE4 A;  2BYR A;  4ZK1 A;  3SIO A;  1UV6 A;  3LSV A;  5J5I A;  4QAC A;  4NZB A;  5SYO A;  3UU4 A;  2Y56 A;  2BG9 C;  2Y57 A;  3ZDG A;  2XZ6 A;  5AFK A;  4UY2 A;  4TWH A;  4HQP A;  4WV9 A;  5AFL A;  3WTI A;  3RQU A;  2BG9 B;  3WTL A;  4ZJT A;  3EAM A;  3IGQ A;  3EI0 A;  3UU5 A;  2XNU A;  4Z91 A;  4ZR6 A;  3UU6 A;  4F8H A;  2YME A;  2XQ5 A;  3P4W A;  2XQA A;  2XQ8 A;  4LMK A;  4TNW A;  4QAB A;  5AFJ A;  3T4M A;  4ILB A;  2C9T A;  5HEJ A;  2X00 A;  4BFQ A;  4XK9 A;  2PH9 A;  1I9B A;  5CO5 A;  2ZJU A;  5BP0 A;  4XHE A;  5FJV A;  5CFB A;  5HCJ A;  3RI5 A;  4PIR A;  2X00 D;  2BG9 E;  3SH1 A;  3WTO A;  3U8K A;  4DBM A;  5BW2 A;  2XYS A;  3C84 A;  3WTJ A;  2VL0 A;  3TLT A;  3UU8 A;  3UQ4 A;  4X5T A;  4ZZB A;  5HEG A;  4HFC A;  5TVC A;  4EZ1 A;  2BG9 A;  4A98 A;  5J5H A;  2XQ4 A;  3RIF A;  5HCM A;  4A97 A;  3RQW A;  4HFB A;  5JME A;  2XQ7 A;  5HEU A;  5J0Z A;  2XQ3 A;  4FRR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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