5KZUA

Crystal structure of an acetylcholine binding protein from aplysia californica (ac-achbp) in complex with click chemistry compound 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole
Total Genus 49
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
49
sequence length
208
structure length
207
Chain Sequence
KLHSQANLMRLKSDLFNRPMYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYYEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPEPYIDVNLVVKFRE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) in complex with click chemistry compound 9-[[1-[8-methyl-8-(2-phenylethyl)-8-azoniabicyclo[3.2.1]octan-3-yl]triazol-4-yl]methyl]carbazole
rcsb
molecule tags Acetylcholine-binding protein
source organism Aplysia californica
molecule keywords Soluble acetylcholine receptor
total genus 49
structure length 207
sequence length 208
chains with identical sequence B, C, D, E
ec nomenclature
pdb deposition date 2016-07-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF02931 Neur_chan_LBD Neurotransmitter-gated ion-channel ligand binding domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
2.70.170.10 Mainly Beta Distorted Sandwich Acetylcholine Binding Protein; Chain: A, Neurotransmitter-gated ion-channel ligand-binding domain 5kzuA00
4ZJSA 4HFHA 4ZK1A 5J5GA 3RIFA 2PH9A 2ZJVA 2XQ6A 3WTIA 2YOEA 2BYQA 4QACA 4UXUA 5HEHA 2PGZA 4ZJTA 2WZYA 4UM3A 5L4HA 4IL4A 3JADA 2YN6A 2X00D 4PIRA 3TLTA 2XZ6A 4UM3P 3UU8A 2X00A 2XQ7A 2XYSA 4A97A 3SQ6A 3SH1A 4D01A 3SIOA 4TWFA 3WTJA 3WTMA 4ZZBA 5BP0A 2W8GA 4TNVA 4UM1A 3WTKA 4Z91A 3TLSA 4QH5A 3UQ7A 5L47A 4FRRA 2YKSA 4BQTA 3C84A 4X5TA 2C9TA 2BYSA 2Y54A 5J5FA 2Y7YA 5J5IA 3EI0A 2YMDA 5AFNA 3WTHA 5KZUA 5AFLA 3WTOA 1UW6A 2Y56A 5FJVA 4ZK4A 5L4EA 3TLUA 4IL9A 4ZRUA 4NPPA 1I9BA 4Z90A 5AINA 4IREA 3SQ9A 3TLVA 3C79A 4QH1A 3JAEA 5CFBA 5SYOA 2XQAA 2UZ6A 5BRXA 2QC1B 3PMZA 3RI5A 3JAFA 3IGQA 2BYNA 4AFHA 4DBMA 2ZJUA 5J5HA 3UU5A 4LMKA 5HCMA 3U8NA 4UY2A 3U8JA 2WN9A 4HFCA 4ZR6A 3RHWA 3WTNA 2XQ8A 4A98A 4HFIA 3U8KA 5BW2A 4F8HA 3TLWA 3UQ4A 2BR7A 2XNUA 2VL0A 2XYTA 5JMEA 3GUAA 4LMLA 4AFGA 3UU4A 5HEOA 5AFMA 3WTLA 2BG9C 3P50A 4XK9A 4EZ1A 3UUBA 4ALXA 5TVCA 5AFHA 5AFMB 3ZDHA 2WNLA 5AFKA 4QH4A 5HEUA 2BG9E 2Y58A 4LMJA 5HEGA 3UU6A 4AFTA 3UU3A 4ZZCA 1UX2A 4HFBA 4ILBA 4XHEA 4B5DA 4TWHA 4TNWA 5LXBA 5CO5A 2BR8A 2XQ5A 5HCJA 4COFA 4HFEA 2WNJA 2XNTA 3RQWA 4TWDA 2XNVA 1UV6A 5IUXA 4ILAA 2XQ3A 2XQ4A 4WV9A 5KE4A 2BJ0A 3RIAA 3T4MA 2XQ9A 5AFJA 3U8LA 5HEJA 4NZBA 2BG9A 3LSVA 2BYPA 2YMEA 4HFDA 3ZDGA 2BYRA 2XZ5A 4QAAA 4UM3S 2BG9B 5LG3A 3EAMA 2Y57A 3U8MA 4BFQA 3P4WA 3WIPA 3EHZA 4ILCA 4QABA 3RQUA 2W8FA 3PEOA 5J0ZA 3ZKRA 4HQPA 2WNCA
chains in the Genus database with same CATH superfamily
4ZJSA 4HFHA 4ZK1A 5J5GA 3RIFA 2PH9A 2ZJVA 2XQ6A 3WTIA 2YOEA 2BYQA 4QACA 4UXUA 5HEHA 2PGZA 4ZJTA 2WZYA 4UM3A 5L4HA 4IL4A 3JADA 2YN6A 2X00D 4PIRA 3TLTA 2XZ6A 4UM3P 3UU8A 2X00A 2XQ7A 2XYSA 4A97A 3SQ6A 3SH1A 4D01A 3SIOA 4TWFA 3WTJA 3WTMA 4ZZBA 5BP0A 2W8GA 4TNVA 4UM1A 3WTKA 4Z91A 3TLSA 4QH5A 3UQ7A 5L47A 4FRRA 2YKSA 4BQTA 3C84A 4X5TA 2C9TA 2BYSA 2Y54A 5J5FA 2Y7YA 5J5IA 3EI0A 2YMDA 5AFNA 3WTHA 5KZUA 5AFLA 3WTOA 1UW6A 2Y56A 5FJVA 4ZK4A 5L4EA 3TLUA 4IL9A 4ZRUA 4NPPA 1I9BA 4Z90A 5AINA 4IREA 3SQ9A 3TLVA 3C79A 4QH1A 3JAEA 5CFBA 5SYOA 2XQAA 2UZ6A 5BRXA 2QC1B 3PMZA 3RI5A 3JAFA 3IGQA 2BYNA 4AFHA 4DBMA 2ZJUA 5J5HA 3UU5A 4LMKA 5HCMA 3U8NA 4UY2A 3U8JA 2WN9A 4HFCA 4ZR6A 3RHWA 3WTNA 2XQ8A 4A98A 4HFIA 3U8KA 5BW2A 4F8HA 3TLWA 3UQ4A 2BR7A 2XNUA 2VL0A 2XYTA 5JMEA 3GUAA 4LMLA 4AFGA 3UU4A 5HEOA 5AFMA 3WTLA 2BG9C 3P50A 4XK9A 4EZ1A 3UUBA 4ALXA 5TVCA 5AFHA 5AFMB 3ZDHA 2WNLA 5AFKA 4QH4A 5HEUA 2BG9E 2Y58A 4LMJA 5HEGA 3UU6A 4AFTA 3UU3A 4ZZCA 1UX2A 4HFBA 4ILBA 4XHEA 4B5DA 4TWHA 4TNWA 5LXBA 5CO5A 2BR8A 2XQ5A 5HCJA 4COFA 4HFEA 2WNJA 2XNTA 3RQWA 4TWDA 2XNVA 1UV6A 5IUXA 4ILAA 2XQ3A 2XQ4A 4WV9A 5KE4A 2BJ0A 3RIAA 3T4MA 2XQ9A 5AFJA 3U8LA 5HEJA 4NZBA 2BG9A 3LSVA 2BYPA 2YMEA 4HFDA 3ZDGA 2BYRA 2XZ5A 4QAAA 4UM3S 2BG9B 5LG3A 3EAMA 2Y57A 3U8MA 4BFQA 3P4WA 3WIPA 3EHZA 4ILCA 4QABA 3RQUA 2W8FA 3PEOA 5J0ZA 3ZKRA 4HQPA 2WNCA
chains in the Genus database with same CATH topology
4ZJSA 4HFHA 4ZK1A 5J5GA 3RIFA 2PH9A 2ZJVA 2XQ6A 3WTIA 2YOEA 2BYQA 4QACA 4UXUA 5HEHA 2PGZA 4ZJTA 2WZYA 4UM3A 5L4HA 4IL4A 3JADA 2YN6A 2X00D 4PIRA 3TLTA 2XZ6A 4UM3P 3UU8A 2X00A 2XQ7A 2XYSA 4A97A 3SQ6A 3SH1A 4D01A 3SIOA 4TWFA 3WTJA 3WTMA 4ZZBA 5BP0A 2W8GA 4TNVA 4UM1A 3WTKA 4Z91A 3TLSA 4QH5A 3UQ7A 5L47A 4FRRA 2YKSA 4BQTA 3C84A 4X5TA 2C9TA 2BYSA 2Y54A 5J5FA 2Y7YA 5J5IA 3EI0A 2YMDA 5AFNA 3WTHA 5KZUA 5AFLA 3WTOA 1UW6A 2Y56A 5FJVA 4ZK4A 5L4EA 3TLUA 4IL9A 4ZRUA 4NPPA 1I9BA 4Z90A 5AINA 4IREA 3SQ9A 3TLVA 3C79A 4QH1A 3JAEA 5CFBA 5SYOA 2XQAA 2UZ6A 5BRXA 2QC1B 3PMZA 3RI5A 3JAFA 3IGQA 2BYNA 4AFHA 4DBMA 2ZJUA 5J5HA 3UU5A 4LMKA 5HCMA 3U8NA 4UY2A 3U8JA 2WN9A 4HFCA 4ZR6A 3RHWA 3WTNA 2XQ8A 4A98A 4HFIA 3U8KA 5BW2A 4F8HA 3TLWA 3UQ4A 2BR7A 2XNUA 2VL0A 2XYTA 5JMEA 3GUAA 4LMLA 4AFGA 3UU4A 5HEOA 5AFMA 3WTLA 2BG9C 3P50A 4XK9A 4EZ1A 3UUBA 4ALXA 5TVCA 5AFHA 5AFMB 3ZDHA 2WNLA 5AFKA 4QH4A 5HEUA 2BG9E 2Y58A 4LMJA 5HEGA 3UU6A 4AFTA 3UU3A 4ZZCA 1UX2A 4HFBA 4ILBA 4XHEA 4B5DA 4TWHA 4TNWA 5LXBA 5CO5A 2BR8A 2XQ5A 5HCJA 4COFA 4HFEA 2WNJA 2XNTA 3RQWA 4TWDA 2XNVA 1UV6A 5IUXA 4ILAA 2XQ3A 2XQ4A 4WV9A 5KE4A 2BJ0A 3RIAA 3T4MA 2XQ9A 5AFJA 3U8LA 5HEJA 4NZBA 2BG9A 3LSVA 2BYPA 2YMEA 4HFDA 3ZDGA 2BYRA 2XZ5A 4QAAA 4UM3S 2BG9B 5LG3A 3EAMA 2Y57A 3U8MA 4BFQA 3P4WA 3WIPA 3EHZA 4ILCA 4QABA 3RQUA 2W8FA 3PEOA 5J0ZA 3ZKRA 4HQPA 2WNCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZJS A;  4HFH A;  4ZK1 A;  5J5G A;  3RIF A;  2PH9 A;  2ZJV A;  2XQ6 A;  3WTI A;  2YOE A;  2BYQ A;  4QAC A;  4UXU A;  5HEH A;  2PGZ A;  4ZJT A;  2WZY A;  4UM3 A;  5L4H A;  4IL4 A;  3JAD A;  2YN6 A;  2X00 D;  4PIR A;  3TLT A;  2XZ6 A;  4UM3 P;  3UU8 A;  2X00 A;  2XQ7 A;  2XYS A;  4A97 A;  3SQ6 A;  3SH1 A;  4D01 A;  3SIO A;  4TWF A;  3WTJ A;  3WTM A;  4ZZB A;  5BP0 A;  2W8G A;  4TNV A;  4UM1 A;  3WTK A;  4Z91 A;  3TLS A;  4QH5 A;  3UQ7 A;  5L47 A;  4FRR A;  2YKS A;  4BQT A;  3C84 A;  4X5T A;  2C9T A;  2BYS A;  2Y54 A;  5J5F A;  2Y7Y A;  5J5I A;  3EI0 A;  2YMD A;  5AFN A;  3WTH A;  5KZU A;  5AFL A;  3WTO A;  1UW6 A;  2Y56 A;  5FJV A;  4ZK4 A;  5L4E A;  3TLU A;  4IL9 A;  4ZRU A;  4NPP A;  1I9B A;  4Z90 A;  5AIN A;  4IRE A;  3SQ9 A;  3TLV A;  3C79 A;  4QH1 A;  3JAE A;  5CFB A;  5SYO A;  2XQA A;  2UZ6 A;  5BRX A;  2QC1 B;  3PMZ A;  3RI5 A;  3JAF A;  3IGQ A;  2BYN A;  4AFH A;  4DBM A;  2ZJU A;  5J5H A;  3UU5 A;  4LMK A;  5HCM A;  3U8N A;  4UY2 A;  3U8J A;  2WN9 A;  4HFC A;  4ZR6 A;  3RHW A;  3WTN A;  2XQ8 A;  4A98 A;  4HFI A;  3U8K A;  5BW2 A;  4F8H A;  3TLW A;  3UQ4 A;  2BR7 A;  2XNU A;  2VL0 A;  2XYT A;  5JME A;  3GUA A;  4LML A;  4AFG A;  3UU4 A;  5HEO A;  5AFM A;  3WTL A;  2BG9 C;  3P50 A;  4XK9 A;  4EZ1 A;  3UUB A;  4ALX A;  5TVC A;  5AFH A;  5AFM B;  3ZDH A;  2WNL A;  5AFK A;  4QH4 A;  5HEU A;  2BG9 E;  2Y58 A;  4LMJ A;  5HEG A;  3UU6 A;  4AFT A;  3UU3 A;  4ZZC A;  1UX2 A;  4HFB A;  4ILB A;  4XHE A;  4B5D A;  4TWH A;  4TNW A;  5LXB A;  5CO5 A;  2BR8 A;  2XQ5 A;  5HCJ A;  4COF A;  4HFE A;  2WNJ A;  2XNT A;  3RQW A;  4TWD A;  2XNV A;  1UV6 A;  5IUX A;  4ILA A;  2XQ3 A;  2XQ4 A;  4WV9 A;  5KE4 A;  2BJ0 A;  3RIA A;  3T4M A;  2XQ9 A;  5AFJ A;  3U8L A;  5HEJ A;  4NZB A;  2BG9 A;  3LSV A;  2BYP A;  2YME A;  4HFD A;  3ZDG A;  2BYR A;  2XZ5 A;  4QAA A;  4UM3 S;  2BG9 B;  5LG3 A;  3EAM A;  2Y57 A;  3U8M A;  4BFQ A;  3P4W A;  3WIP A;  3EHZ A;  4ILC A;  4QAB A;  3RQU A;  2W8F A;  3PEO A;  5J0Z A;  3ZKR A;  4HQP A;  2WNC A; 
#chains in the Genus database with same CATH topology
 4ZJS A;  4HFH A;  4ZK1 A;  5J5G A;  3RIF A;  2PH9 A;  2ZJV A;  2XQ6 A;  3WTI A;  2YOE A;  2BYQ A;  4QAC A;  4UXU A;  5HEH A;  2PGZ A;  4ZJT A;  2WZY A;  4UM3 A;  5L4H A;  4IL4 A;  3JAD A;  2YN6 A;  2X00 D;  4PIR A;  3TLT A;  2XZ6 A;  4UM3 P;  3UU8 A;  2X00 A;  2XQ7 A;  2XYS A;  4A97 A;  3SQ6 A;  3SH1 A;  4D01 A;  3SIO A;  4TWF A;  3WTJ A;  3WTM A;  4ZZB A;  5BP0 A;  2W8G A;  4TNV A;  4UM1 A;  3WTK A;  4Z91 A;  3TLS A;  4QH5 A;  3UQ7 A;  5L47 A;  4FRR A;  2YKS A;  4BQT A;  3C84 A;  4X5T A;  2C9T A;  2BYS A;  2Y54 A;  5J5F A;  2Y7Y A;  5J5I A;  3EI0 A;  2YMD A;  5AFN A;  3WTH A;  5KZU A;  5AFL A;  3WTO A;  1UW6 A;  2Y56 A;  5FJV A;  4ZK4 A;  5L4E A;  3TLU A;  4IL9 A;  4ZRU A;  4NPP A;  1I9B A;  4Z90 A;  5AIN A;  4IRE A;  3SQ9 A;  3TLV A;  3C79 A;  4QH1 A;  3JAE A;  5CFB A;  5SYO A;  2XQA A;  2UZ6 A;  5BRX A;  2QC1 B;  3PMZ A;  3RI5 A;  3JAF A;  3IGQ A;  2BYN A;  4AFH A;  4DBM A;  2ZJU A;  5J5H A;  3UU5 A;  4LMK A;  5HCM A;  3U8N A;  4UY2 A;  3U8J A;  2WN9 A;  4HFC A;  4ZR6 A;  3RHW A;  3WTN A;  2XQ8 A;  4A98 A;  4HFI A;  3U8K A;  5BW2 A;  4F8H A;  3TLW A;  3UQ4 A;  2BR7 A;  2XNU A;  2VL0 A;  2XYT A;  5JME A;  3GUA A;  4LML A;  4AFG A;  3UU4 A;  5HEO A;  5AFM A;  3WTL A;  2BG9 C;  3P50 A;  4XK9 A;  4EZ1 A;  3UUB A;  4ALX A;  5TVC A;  5AFH A;  5AFM B;  3ZDH A;  2WNL A;  5AFK A;  4QH4 A;  5HEU A;  2BG9 E;  2Y58 A;  4LMJ A;  5HEG A;  3UU6 A;  4AFT A;  3UU3 A;  4ZZC A;  1UX2 A;  4HFB A;  4ILB A;  4XHE A;  4B5D A;  4TWH A;  4TNW A;  5LXB A;  5CO5 A;  2BR8 A;  2XQ5 A;  5HCJ A;  4COF A;  4HFE A;  2WNJ A;  2XNT A;  3RQW A;  4TWD A;  2XNV A;  1UV6 A;  5IUX A;  4ILA A;  2XQ3 A;  2XQ4 A;  4WV9 A;  5KE4 A;  2BJ0 A;  3RIA A;  3T4M A;  2XQ9 A;  5AFJ A;  3U8L A;  5HEJ A;  4NZB A;  2BG9 A;  3LSV A;  2BYP A;  2YME A;  4HFD A;  3ZDG A;  2BYR A;  2XZ5 A;  4QAA A;  4UM3 S;  2BG9 B;  5LG3 A;  3EAM A;  2Y57 A;  3U8M A;  4BFQ A;  3P4W A;  3WIP A;  3EHZ A;  4ILC A;  4QAB A;  3RQU A;  2W8F A;  3PEO A;  5J0Z A;  3ZKR A;  4HQP A;  2WNC A; 
#chains in the Genus database with same CATH homology
 4ZJS A;  4HFH A;  4ZK1 A;  5J5G A;  3RIF A;  2PH9 A;  2ZJV A;  2XQ6 A;  3WTI A;  2YOE A;  2BYQ A;  4QAC A;  4UXU A;  5HEH A;  2PGZ A;  4ZJT A;  2WZY A;  4UM3 A;  5L4H A;  4IL4 A;  3JAD A;  2YN6 A;  2X00 D;  4PIR A;  3TLT A;  2XZ6 A;  4UM3 P;  3UU8 A;  2X00 A;  2XQ7 A;  2XYS A;  4A97 A;  3SQ6 A;  3SH1 A;  4D01 A;  3SIO A;  4TWF A;  3WTJ A;  3WTM A;  4ZZB A;  5BP0 A;  2W8G A;  4TNV A;  4UM1 A;  3WTK A;  4Z91 A;  3TLS A;  4QH5 A;  3UQ7 A;  5L47 A;  4FRR A;  2YKS A;  4BQT A;  3C84 A;  4X5T A;  2C9T A;  2BYS A;  2Y54 A;  5J5F A;  2Y7Y A;  5J5I A;  3EI0 A;  2YMD A;  5AFN A;  3WTH A;  5KZU A;  5AFL A;  3WTO A;  1UW6 A;  2Y56 A;  5FJV A;  4ZK4 A;  5L4E A;  3TLU A;  4IL9 A;  4ZRU A;  4NPP A;  1I9B A;  4Z90 A;  5AIN A;  4IRE A;  3SQ9 A;  3TLV A;  3C79 A;  4QH1 A;  3JAE A;  5CFB A;  5SYO A;  2XQA A;  2UZ6 A;  5BRX A;  2QC1 B;  3PMZ A;  3RI5 A;  3JAF A;  3IGQ A;  2BYN A;  4AFH A;  4DBM A;  2ZJU A;  5J5H A;  3UU5 A;  4LMK A;  5HCM A;  3U8N A;  4UY2 A;  3U8J A;  2WN9 A;  4HFC A;  4ZR6 A;  3RHW A;  3WTN A;  2XQ8 A;  4A98 A;  4HFI A;  3U8K A;  5BW2 A;  4F8H A;  3TLW A;  3UQ4 A;  2BR7 A;  2XNU A;  2VL0 A;  2XYT A;  5JME A;  3GUA A;  4LML A;  4AFG A;  3UU4 A;  5HEO A;  5AFM A;  3WTL A;  2BG9 C;  3P50 A;  4XK9 A;  4EZ1 A;  3UUB A;  4ALX A;  5TVC A;  5AFH A;  5AFM B;  3ZDH A;  2WNL A;  5AFK A;  4QH4 A;  5HEU A;  2BG9 E;  2Y58 A;  4LMJ A;  5HEG A;  3UU6 A;  4AFT A;  3UU3 A;  4ZZC A;  1UX2 A;  4HFB A;  4ILB A;  4XHE A;  4B5D A;  4TWH A;  4TNW A;  5LXB A;  5CO5 A;  2BR8 A;  2XQ5 A;  5HCJ A;  4COF A;  4HFE A;  2WNJ A;  2XNT A;  3RQW A;  4TWD A;  2XNV A;  1UV6 A;  5IUX A;  4ILA A;  2XQ3 A;  2XQ4 A;  4WV9 A;  5KE4 A;  2BJ0 A;  3RIA A;  3T4M A;  2XQ9 A;  5AFJ A;  3U8L A;  5HEJ A;  4NZB A;  2BG9 A;  3LSV A;  2BYP A;  2YME A;  4HFD A;  3ZDG A;  2BYR A;  2XZ5 A;  4QAA A;  4UM3 S;  2BG9 B;  5LG3 A;  3EAM A;  2Y57 A;  3U8M A;  4BFQ A;  3P4W A;  3WIP A;  3EHZ A;  4ILC A;  4QAB A;  3RQU A;  2W8F A;  3PEO A;  5J0Z A;  3ZKR A;  4HQP A;  2WNC A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...