5TVC | Genus

Total Genus 47

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus	47
sequence length	216
structure length	211
Chain Sequence	DKLHSQANLMRLKSDLFYPGPTKDDPLTVTLGFTLQDIVKADSSTNEVDLVYWEQQRWKLNSLMWDPNEYGNITDFRTSAADIWTPDITAYSSTRPVQVLSPQIAVVTHDGSVMFIPAQRLSFMCDPTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQYKHDIKYNCCEEIYPDVVLVVKFRERRAGNGF

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

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After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Genus data interpretation

Chord Diagram

molecule tags	Acetylcholine-binding protein
source organism	Aplysia californica
publication title	Crystal structure of a chimeric acetylcholine binding protein from Aplysia californica (Ac-AChBP) containing loop C from the human alpha 3 nicotinic acetylcholine receptor in complex with (E,2S)-N-methyl-5-(5-phenoxy-3-pyridyl)pent-4-en-2-amine (TI-5312) rcsb
molecule keywords	Soluble acetylcholine receptor,Neuronal acetylcholine recept
total genus	47
structure length	211
sequence length	216
chains with identical sequence	B, C, D, E
ec nomenclature
pdb deposition date	2016-11-08

pfam database annotations

chain	Pfam Accession Code	Pfam Family Identifier	Pfam Description
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain
A	PF02931	Neur_chan_LBD	Neurotransmitter-gated ion-channel ligand binding domain

Image from the rcsb pdb (www.rcsb.org)

cath code	Class	Architecture	Topology	Homology	Domain
2.70.170.10	Mainly Beta	Distorted Sandwich	Acetylcholine Binding Protein; Chain: A,	Neurotransmitter-gated ion-channel ligand-binding domain	5tvcA00

4QABA 3TLWA 5AFLA 1I9BA 5SYOA 3JADA 4HFBA 3RI5A 5J5FA 3U8JA 2YMEA 4QH5A 2BYSA 3TLVA 3WTHA 3WTNA 5AFKA 3JAEA 2Y56A 4COFA 2XZ6A 2XQ7A 4TWHA 2UZ6A 5TVCA 4XK9A 3ZKRA 4HQPA 5LG3A 3JAFA 3UU4A 1UX2A 3SQ9A 2W8FA 1UW6A 4ZJSA 3SH1A 3RQWA 2Y57A 3WTKA 5J5IA 4ALXA 3LSVA 2PGZA 4NPPA 4UM1A 5HEOA 3WTJA 4D01A 3WTLA 2XQ5A 5AINA 4LMLA 5AFMA 5AFNA 5FJVA 4Z90A 5HEJA 2BYPA 3PEOA 2Y58A 5J5GA 3UUBA 4FRRA 2XZ5A 5CFBA 1UV6A 2XQAA 5JMEA 2BR7A 4HFHA 4IL9A 2W8GA 2BR8A 2X00D 2ZJVA 2XNUA 4ZK4A 5KZUA 4BFQA 4TNVA 2XNVA 3RIAA 4AFHA 4ZK1A 3RIFA 4ILCA 3EHZA 5L4EA 4ZZBA 5HCJA 3GUAA 2C9TA 2XYSA 2YMDA 4X5TA 2WNCA 4TWDA 4BQTA 3PMZA 5HCMA 4XHEA 3T4MA 2BG9A 2BYRA 3U8NA 5L4HA 4HFCA 4TNWA 4AFTA 5KE4A 3TLSA 4ZRUA 5AFJA 3IGQA 2VL0A 3SIOA 2XNTA 4IL4A 4TWFA 2PH9A 4LMKA 5IUXA 4ILBA 3U8KA 4NZBA 5BRXA 2XYTA 5HEHA 3WIPA 2BG9C 2XQ9A 2X00A 4ZR6A 4EZ1A 4Z91A 3UQ4A 4IREA 5HEGA 3EAMA 2QC1B 2Y54A 2XQ4A 3P4WA 2WN9A 3U8MA 2XQ3A 5AFMB 4HFEA 5LXBA 2ZJUA 5BW2A 3UU8A 3TLUA 2WNLA 2XQ8A 4LMJA 4UXUA 5HEUA 3U8LA 4PIRA 3WTOA 3ZDHA 2YN6A 4HFIA 3UU6A 3TLTA 4F8HA 5AFHA 4ILAA 3WTMA 3EI0A 3ZDGA 3UU5A 4ZZCA 3SQ6A 4QAAA 2XQ6A 3WTIA 4A97A 4ZJTA 2WNJA 2Y7YA 2BYNA 4UM3P 4UY2A 5J5HA 4B5DA 5J0ZA 4QH4A 4A98A 4DBMA 4UM3A 4HFDA 3C84A 2BG9E 3RQUA 3UQ7A 4WV9A 2BG9B 5L47A 4QH1A 2WZYA 2YOEA 4AFGA 3RHWA 5BP0A 3UU3A 4UM3S 3C79A 2BJ0A 2BYQA 4QACA 5CO5A 2YKSA 3P50A
chains in the Genus database with same CATH superfamily

#chains in the Genus database with same CATH superfamily
 4QAB A;  3TLW A;  5AFL A;  1I9B A;  5SYO A;  3JAD A;  4HFB A;  3RI5 A;  5J5F A;  3U8J A;  2YME A;  4QH5 A;  2BYS A;  3TLV A;  3WTH A;  3WTN A;  5AFK A;  3JAE A;  2Y56 A;  4COF A;  2XZ6 A;  2XQ7 A;  4TWH A;  2UZ6 A;  5TVC A;  4XK9 A;  3ZKR A;  4HQP A;  5LG3 A;  3JAF A;  3UU4 A;  1UX2 A;  3SQ9 A;  2W8F A;  1UW6 A;  4ZJS A;  3SH1 A;  3RQW A;  2Y57 A;  3WTK A;  5J5I A;  4ALX A;  3LSV A;  2PGZ A;  4NPP A;  4UM1 A;  5HEO A;  3WTJ A;  4D01 A;  3WTL A;  2XQ5 A;  5AIN A;  4LML A;  5AFM A;  5AFN A;  5FJV A;  4Z90 A;  5HEJ A;  2BYP A;  3PEO A;  2Y58 A;  5J5G A;  3UUB A;  4FRR A;  2XZ5 A;  5CFB A;  1UV6 A;  2XQA A;  5JME A;  2BR7 A;  4HFH A;  4IL9 A;  2W8G A;  2BR8 A;  2X00 D;  2ZJV A;  2XNU A;  4ZK4 A;  5KZU A;  4BFQ A;  4TNV A;  2XNV A;  3RIA A;  4AFH A;  4ZK1 A;  3RIF A;  4ILC A;  3EHZ A;  5L4E A;  4ZZB A;  5HCJ A;  3GUA A;  2C9T A;  2XYS A;  2YMD A;  4X5T A;  2WNC A;  4TWD A;  4BQT A;  3PMZ A;  5HCM A;  4XHE A;  3T4M A;  2BG9 A;  2BYR A;  3U8N A;  5L4H A;  4HFC A;  4TNW A;  4AFT A;  5KE4 A;  3TLS A;  4ZRU A;  5AFJ A;  3IGQ A;  2VL0 A;  3SIO A;  2XNT A;  4IL4 A;  4TWF A;  2PH9 A;  4LMK A;  5IUX A;  4ILB A;  3U8K A;  4NZB A;  5BRX A;  2XYT A;  5HEH A;  3WIP A;  2BG9 C;  2XQ9 A;  2X00 A;  4ZR6 A;  4EZ1 A;  4Z91 A;  3UQ4 A;  4IRE A;  5HEG A;  3EAM A;  2QC1 B;  2Y54 A;  2XQ4 A;  3P4W A;  2WN9 A;  3U8M A;  2XQ3 A;  5AFM B;  4HFE A;  5LXB A;  2ZJU A;  5BW2 A;  3UU8 A;  3TLU A;  2WNL A;  2XQ8 A;  4LMJ A;  4UXU A;  5HEU A;  3U8L A;  4PIR A;  3WTO A;  3ZDH A;  2YN6 A;  4HFI A;  3UU6 A;  3TLT A;  4F8H A;  5AFH A;  4ILA A;  3WTM A;  3EI0 A;  3ZDG A;  3UU5 A;  4ZZC A;  3SQ6 A;  4QAA A;  2XQ6 A;  3WTI A;  4A97 A;  4ZJT A;  2WNJ A;  2Y7Y A;  2BYN A;  4UM3 P;  4UY2 A;  5J5H A;  4B5D A;  5J0Z A;  4QH4 A;  4A98 A;  4DBM A;  4UM3 A;  4HFD A;  3C84 A;  2BG9 E;  3RQU A;  3UQ7 A;  4WV9 A;  2BG9 B;  5L47 A;  4QH1 A;  2WZY A;  2YOE A;  4AFG A;  3RHW A;  5BP0 A;  3UU3 A;  4UM3 S;  3C79 A;  2BJ0 A;  2BYQ A;  4QAC A;  5CO5 A;  2YKS A;  3P50 A; 
#chains in the Genus database with same CATH topology
 4QAB A;  3TLW A;  5AFL A;  1I9B A;  5SYO A;  3JAD A;  4HFB A;  3RI5 A;  5J5F A;  3U8J A;  2YME A;  4QH5 A;  2BYS A;  3TLV A;  3WTH A;  3WTN A;  5AFK A;  3JAE A;  2Y56 A;  4COF A;  2XZ6 A;  2XQ7 A;  4TWH A;  2UZ6 A;  5TVC A;  4XK9 A;  3ZKR A;  4HQP A;  5LG3 A;  3JAF A;  3UU4 A;  1UX2 A;  3SQ9 A;  2W8F A;  1UW6 A;  4ZJS A;  3SH1 A;  3RQW A;  2Y57 A;  3WTK A;  5J5I A;  4ALX A;  3LSV A;  2PGZ A;  4NPP A;  4UM1 A;  5HEO A;  3WTJ A;  4D01 A;  3WTL A;  2XQ5 A;  5AIN A;  4LML A;  5AFM A;  5AFN A;  5FJV A;  4Z90 A;  5HEJ A;  2BYP A;  3PEO A;  2Y58 A;  5J5G A;  3UUB A;  4FRR A;  2XZ5 A;  5CFB A;  1UV6 A;  2XQA A;  5JME A;  2BR7 A;  4HFH A;  4IL9 A;  2W8G A;  2BR8 A;  2X00 D;  2ZJV A;  2XNU A;  4ZK4 A;  5KZU A;  4BFQ A;  4TNV A;  2XNV A;  3RIA A;  4AFH A;  4ZK1 A;  3RIF A;  4ILC A;  3EHZ A;  5L4E A;  4ZZB A;  5HCJ A;  3GUA A;  2C9T A;  2XYS A;  2YMD A;  4X5T A;  2WNC A;  4TWD A;  4BQT A;  3PMZ A;  5HCM A;  4XHE A;  3T4M A;  2BG9 A;  2BYR A;  3U8N A;  5L4H A;  4HFC A;  4TNW A;  4AFT A;  5KE4 A;  3TLS A;  4ZRU A;  5AFJ A;  3IGQ A;  2VL0 A;  3SIO A;  2XNT A;  4IL4 A;  4TWF A;  2PH9 A;  4LMK A;  5IUX A;  4ILB A;  3U8K A;  4NZB A;  5BRX A;  2XYT A;  5HEH A;  3WIP A;  2BG9 C;  2XQ9 A;  2X00 A;  4ZR6 A;  4EZ1 A;  4Z91 A;  3UQ4 A;  4IRE A;  5HEG A;  3EAM A;  2QC1 B;  2Y54 A;  2XQ4 A;  3P4W A;  2WN9 A;  3U8M A;  2XQ3 A;  5AFM B;  4HFE A;  5LXB A;  2ZJU A;  5BW2 A;  3UU8 A;  3TLU A;  2WNL A;  2XQ8 A;  4LMJ A;  4UXU A;  5HEU A;  3U8L A;  4PIR A;  3WTO A;  3ZDH A;  2YN6 A;  4HFI A;  3UU6 A;  3TLT A;  4F8H A;  5AFH A;  4ILA A;  3WTM A;  3EI0 A;  3ZDG A;  3UU5 A;  4ZZC A;  3SQ6 A;  4QAA A;  2XQ6 A;  3WTI A;  4A97 A;  4ZJT A;  2WNJ A;  2Y7Y A;  2BYN A;  4UM3 P;  4UY2 A;  5J5H A;  4B5D A;  5J0Z A;  4QH4 A;  4A98 A;  4DBM A;  4UM3 A;  4HFD A;  3C84 A;  2BG9 E;  3RQU A;  3UQ7 A;  4WV9 A;  2BG9 B;  5L47 A;  4QH1 A;  2WZY A;  2YOE A;  4AFG A;  3RHW A;  5BP0 A;  3UU3 A;  4UM3 S;  3C79 A;  2BJ0 A;  2BYQ A;  4QAC A;  5CO5 A;  2YKS A;  3P50 A; 
#chains in the Genus database with same CATH homology
 4QAB A;  3TLW A;  5AFL A;  1I9B A;  5SYO A;  3JAD A;  4HFB A;  3RI5 A;  5J5F A;  3U8J A;  2YME A;  4QH5 A;  2BYS A;  3TLV A;  3WTH A;  3WTN A;  5AFK A;  3JAE A;  2Y56 A;  4COF A;  2XZ6 A;  2XQ7 A;  4TWH A;  2UZ6 A;  5TVC A;  4XK9 A;  3ZKR A;  4HQP A;  5LG3 A;  3JAF A;  3UU4 A;  1UX2 A;  3SQ9 A;  2W8F A;  1UW6 A;  4ZJS A;  3SH1 A;  3RQW A;  2Y57 A;  3WTK A;  5J5I A;  4ALX A;  3LSV A;  2PGZ A;  4NPP A;  4UM1 A;  5HEO A;  3WTJ A;  4D01 A;  3WTL A;  2XQ5 A;  5AIN A;  4LML A;  5AFM A;  5AFN A;  5FJV A;  4Z90 A;  5HEJ A;  2BYP A;  3PEO A;  2Y58 A;  5J5G A;  3UUB A;  4FRR A;  2XZ5 A;  5CFB A;  1UV6 A;  2XQA A;  5JME A;  2BR7 A;  4HFH A;  4IL9 A;  2W8G A;  2BR8 A;  2X00 D;  2ZJV A;  2XNU A;  4ZK4 A;  5KZU A;  4BFQ A;  4TNV A;  2XNV A;  3RIA A;  4AFH A;  4ZK1 A;  3RIF A;  4ILC A;  3EHZ A;  5L4E A;  4ZZB A;  5HCJ A;  3GUA A;  2C9T A;  2XYS A;  2YMD A;  4X5T A;  2WNC A;  4TWD A;  4BQT A;  3PMZ A;  5HCM A;  4XHE A;  3T4M A;  2BG9 A;  2BYR A;  3U8N A;  5L4H A;  4HFC A;  4TNW A;  4AFT A;  5KE4 A;  3TLS A;  4ZRU A;  5AFJ A;  3IGQ A;  2VL0 A;  3SIO A;  2XNT A;  4IL4 A;  4TWF A;  2PH9 A;  4LMK A;  5IUX A;  4ILB A;  3U8K A;  4NZB A;  5BRX A;  2XYT A;  5HEH A;  3WIP A;  2BG9 C;  2XQ9 A;  2X00 A;  4ZR6 A;  4EZ1 A;  4Z91 A;  3UQ4 A;  4IRE A;  5HEG A;  3EAM A;  2QC1 B;  2Y54 A;  2XQ4 A;  3P4W A;  2WN9 A;  3U8M A;  2XQ3 A;  5AFM B;  4HFE A;  5LXB A;  2ZJU A;  5BW2 A;  3UU8 A;  3TLU A;  2WNL A;  2XQ8 A;  4LMJ A;  4UXU A;  5HEU A;  3U8L A;  4PIR A;  3WTO A;  3ZDH A;  2YN6 A;  4HFI A;  3UU6 A;  3TLT A;  4F8H A;  5AFH A;  4ILA A;  3WTM A;  3EI0 A;  3ZDG A;  3UU5 A;  4ZZC A;  3SQ6 A;  4QAA A;  2XQ6 A;  3WTI A;  4A97 A;  4ZJT A;  2WNJ A;  2Y7Y A;  2BYN A;  4UM3 P;  4UY2 A;  5J5H A;  4B5D A;  5J0Z A;  4QH4 A;  4A98 A;  4DBM A;  4UM3 A;  4HFD A;  3C84 A;  2BG9 E;  3RQU A;  3UQ7 A;  4WV9 A;  2BG9 B;  5L47 A;  4QH1 A;  2WZY A;  2YOE A;  4AFG A;  3RHW A;  5BP0 A;  3UU3 A;  4UM3 S;  3C79 A;  2BJ0 A;  2BYQ A;  4QAC A;  5CO5 A;  2YKS A;  3P50 A;

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similar chains in the Genus database (?% sequence similarity)

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similar chains in the pdb database (?% sequence similarity)

#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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5TVCA

Total Genus

sequence length

structure length

Chain Sequence

Structure visualization

Chord Diagram

connected with : NaN

pfam database annotations