The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.
Total Genus |
51
|
sequence length |
209
|
structure length |
204
|
Chain Sequence |
DDDKLDRADILYNIRQTSRPDVIPTQRDRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSSHSPDQVSVPISSLWVPDLAAYNAISKPEVLTPQLARVVSDGEVLYMPSIRQRFSCDVSGVDTESGATCRIKIGSWTHHSREISVDPTDSEYFSQYSRFEILDVTQKKNSVTYSCCPEAYEDVEVSLNFRKKG
|
The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.
After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.
| publication title |
Substituted 2-Aminopyrimidines Selective for alpha 7-Nicotinic Acetylcholine Receptor Activation and Association with Acetylcholine Binding Proteins.
pubmed doi rcsb |
| molecule keywords |
Acetylcholine-binding protein
|
| molecule tags |
Acetylcholine-binding protein
|
| source organism |
Lymnaea stagnalis
|
| total genus |
51
|
| structure length |
204
|
| sequence length |
209
|
| chains with identical sequence |
B, C, D, E, F, G, H, I, J
|
| ec nomenclature | |
| pdb deposition date | 2016-04-02 |
| chain | Pfam Accession Code | Pfam Family Identifier | Pfam Description |
|---|---|---|---|
| A | PF02931 | Neur_chan_LBD | Neurotransmitter-gated ion-channel ligand binding domain |
Image from the rcsb pdb (www.rcsb.org)
cath code
| Class | Architecture | Topology | Homology | Domain |
|---|---|---|---|---|---|
| Mainly Beta | Distorted Sandwich | Acetylcholine Binding Protein; Chain: A, | Neurotransmitter-gated ion-channel ligand-binding domain |
#chains in the Genus database with same CATH superfamily 3PEO A; 4TNV A; 2XNV A; 3U8K A; 4UM3 A; 1UW6 A; 4UM3 P; 3UQ7 A; 2BJ0 A; 2Y57 A; 3RQU A; 3WTN A; 2BYP A; 3TLW A; 4A98 A; 5KZU A; 4TWH A; 4HFE A; 2YME A; 5L4H A; 5J5H A; 5TVC A; 4UY2 A; 5L4E A; 2PH9 A; 4B5D A; 5SYO A; 5HCM A; 4LML A; 3EAM A; 4HFI A; 4QAC A; 4DBM A; 4ZK4 A; 5HEU A; 4LMJ A; 5L47 A; 2W8F A; 5HEG A; 4A97 A; 4WV9 A; 5J5G A; 2XZ6 A; 5HEO A; 3WTH A; 5J5I A; 3WTK A; 4BFQ A; 2Y58 A; 5AFH A; 5FJV A; 4QAB A; 2XQ5 A; 3ZDH A; 2Y56 A; 3U8M A; 2YN6 A; 3UUB A; 4PIR A; 4Z91 A; 5KE4 A; 4EZ1 A; 2X00 D; 2XQ4 A; 4HFH A; 5CFB A; 4NZB A; 3JAF A; 3P4W A; 4TWD A; 3EHZ A; 2XNT A; 2XQ3 A; 4TWF A; 2UZ6 A; 3UU5 A; 4UXU A; 3WTJ A; 3IGQ A; 4D01 A; 4AFH A; 3TLT A; 4X5T A; 2XQ7 A; 5AFM A; 5BP0 A; 4QH1 A; 5J5F A; 2BG9 A; 3RI5 A; 2BR8 A; 2Y7Y A; 3PMZ A; 2PGZ A; 4UM3 S; 4HFD A; 4NPP A; 3WTI A; 4QAA A; 4XK9 A; 4ILB A; 4ILC A; 4COF A; 4ZRU A; 2XYT A; 4HFC A; 3ZKR A; 3SQ9 A; 5CO5 A; 5HEH A; 3WIP A; 2BR7 A; 2QC1 B; 2YKS A; 4ZZC A; 3LSV A; 3GUA A; 2BG9 E; 2WNL A; 2YMD A; 4IL9 A; 4Z90 A; 4ILA A; 4LMK A; 5BW2 A; 4ZR6 A; 2XQ6 A; 3JAE A; 3RIF A; 5AFN A; 3SQ6 A; 5HEJ A; 5IUX A; 2X00 A; 2XQ8 A; 3U8N A; 2BYR A; 2XNU A; 3WTL A; 5BRX A; 2YOE A; 4QH4 A; 1UX2 A; 2VL0 A; 2Y54 A; 4FRR A; 4HQP A; 4IRE A; 3C79 A; 3UU6 A; 2BYN A; 3SH1 A; 4ZK1 A; 3UU8 A; 2C9T A; 5J0Z A; 4ALX A; 3C84 A; 3RQW A; 3P50 A; 5HCJ A; 2WNC A; 3U8L A; 3T4M A; 2ZJV A; 3RIA A; 5JME A; 5LXB A; 5LG3 A; 3UU3 A; 2XYS A; 4F8H A; 3RHW A; 3SIO A; 3WTO A; 3TLU A; 4ZJT A; 5AFM B; 2BG9 C; 4TNW A; 3TLV A; 5AFK A; 4IL4 A; 3U8J A; 2BG9 B; 4AFG A; 5AFJ A; 1I9B A; 2XQ9 A; 4ZZB A; 3TLS A; 2WZY A; 2XQA A; 3WTM A; 4UM1 A; 3JAD A; 5AIN A; 2XZ5 A; 2BYS A; 5AFL A; 2BYQ A; 2WN9 A; 4QH5 A; 3UQ4 A; 3ZDG A; 2WNJ A; 1UV6 A; 4BQT A; 4AFT A; 4XHE A; 3UU4 A; 2ZJU A; 3EI0 A; 4ZJS A; 4HFB A; 2W8G A; #chains in the Genus database with same CATH topology 3PEO A; 4TNV A; 2XNV A; 3U8K A; 4UM3 A; 1UW6 A; 4UM3 P; 3UQ7 A; 2BJ0 A; 2Y57 A; 3RQU A; 3WTN A; 2BYP A; 3TLW A; 4A98 A; 5KZU A; 4TWH A; 4HFE A; 2YME A; 5L4H A; 5J5H A; 5TVC A; 4UY2 A; 5L4E A; 2PH9 A; 4B5D A; 5SYO A; 5HCM A; 4LML A; 3EAM A; 4HFI A; 4QAC A; 4DBM A; 4ZK4 A; 5HEU A; 4LMJ A; 5L47 A; 2W8F A; 5HEG A; 4A97 A; 4WV9 A; 5J5G A; 2XZ6 A; 5HEO A; 3WTH A; 5J5I A; 3WTK A; 4BFQ A; 2Y58 A; 5AFH A; 5FJV A; 4QAB A; 2XQ5 A; 3ZDH A; 2Y56 A; 3U8M A; 2YN6 A; 3UUB A; 4PIR A; 4Z91 A; 5KE4 A; 4EZ1 A; 2X00 D; 2XQ4 A; 4HFH A; 5CFB A; 4NZB A; 3JAF A; 3P4W A; 4TWD A; 3EHZ A; 2XNT A; 2XQ3 A; 4TWF A; 2UZ6 A; 3UU5 A; 4UXU A; 3WTJ A; 3IGQ A; 4D01 A; 4AFH A; 3TLT A; 4X5T A; 2XQ7 A; 5AFM A; 5BP0 A; 4QH1 A; 5J5F A; 2BG9 A; 3RI5 A; 2BR8 A; 2Y7Y A; 3PMZ A; 2PGZ A; 4UM3 S; 4HFD A; 4NPP A; 3WTI A; 4QAA A; 4XK9 A; 4ILB A; 4ILC A; 4COF A; 4ZRU A; 2XYT A; 4HFC A; 3ZKR A; 3SQ9 A; 5CO5 A; 5HEH A; 3WIP A; 2BR7 A; 2QC1 B; 2YKS A; 4ZZC A; 3LSV A; 3GUA A; 2BG9 E; 2WNL A; 2YMD A; 4IL9 A; 4Z90 A; 4ILA A; 4LMK A; 5BW2 A; 4ZR6 A; 2XQ6 A; 3JAE A; 3RIF A; 5AFN A; 3SQ6 A; 5HEJ A; 5IUX A; 2X00 A; 2XQ8 A; 3U8N A; 2BYR A; 2XNU A; 3WTL A; 5BRX A; 2YOE A; 4QH4 A; 1UX2 A; 2VL0 A; 2Y54 A; 4FRR A; 4HQP A; 4IRE A; 3C79 A; 3UU6 A; 2BYN A; 3SH1 A; 4ZK1 A; 3UU8 A; 2C9T A; 5J0Z A; 4ALX A; 3C84 A; 3RQW A; 3P50 A; 5HCJ A; 2WNC A; 3U8L A; 3T4M A; 2ZJV A; 3RIA A; 5JME A; 5LXB A; 5LG3 A; 3UU3 A; 2XYS A; 4F8H A; 3RHW A; 3SIO A; 3WTO A; 3TLU A; 4ZJT A; 5AFM B; 2BG9 C; 4TNW A; 3TLV A; 5AFK A; 4IL4 A; 3U8J A; 2BG9 B; 4AFG A; 5AFJ A; 1I9B A; 2XQ9 A; 4ZZB A; 3TLS A; 2WZY A; 2XQA A; 3WTM A; 4UM1 A; 3JAD A; 5AIN A; 2XZ5 A; 2BYS A; 5AFL A; 2BYQ A; 2WN9 A; 4QH5 A; 3UQ4 A; 3ZDG A; 2WNJ A; 1UV6 A; 4BQT A; 4AFT A; 4XHE A; 3UU4 A; 2ZJU A; 3EI0 A; 4ZJS A; 4HFB A; 2W8G A; #chains in the Genus database with same CATH homology 3PEO A; 4TNV A; 2XNV A; 3U8K A; 4UM3 A; 1UW6 A; 4UM3 P; 3UQ7 A; 2BJ0 A; 2Y57 A; 3RQU A; 3WTN A; 2BYP A; 3TLW A; 4A98 A; 5KZU A; 4TWH A; 4HFE A; 2YME A; 5L4H A; 5J5H A; 5TVC A; 4UY2 A; 5L4E A; 2PH9 A; 4B5D A; 5SYO A; 5HCM A; 4LML A; 3EAM A; 4HFI A; 4QAC A; 4DBM A; 4ZK4 A; 5HEU A; 4LMJ A; 5L47 A; 2W8F A; 5HEG A; 4A97 A; 4WV9 A; 5J5G A; 2XZ6 A; 5HEO A; 3WTH A; 5J5I A; 3WTK A; 4BFQ A; 2Y58 A; 5AFH A; 5FJV A; 4QAB A; 2XQ5 A; 3ZDH A; 2Y56 A; 3U8M A; 2YN6 A; 3UUB A; 4PIR A; 4Z91 A; 5KE4 A; 4EZ1 A; 2X00 D; 2XQ4 A; 4HFH A; 5CFB A; 4NZB A; 3JAF A; 3P4W A; 4TWD A; 3EHZ A; 2XNT A; 2XQ3 A; 4TWF A; 2UZ6 A; 3UU5 A; 4UXU A; 3WTJ A; 3IGQ A; 4D01 A; 4AFH A; 3TLT A; 4X5T A; 2XQ7 A; 5AFM A; 5BP0 A; 4QH1 A; 5J5F A; 2BG9 A; 3RI5 A; 2BR8 A; 2Y7Y A; 3PMZ A; 2PGZ A; 4UM3 S; 4HFD A; 4NPP A; 3WTI A; 4QAA A; 4XK9 A; 4ILB A; 4ILC A; 4COF A; 4ZRU A; 2XYT A; 4HFC A; 3ZKR A; 3SQ9 A; 5CO5 A; 5HEH A; 3WIP A; 2BR7 A; 2QC1 B; 2YKS A; 4ZZC A; 3LSV A; 3GUA A; 2BG9 E; 2WNL A; 2YMD A; 4IL9 A; 4Z90 A; 4ILA A; 4LMK A; 5BW2 A; 4ZR6 A; 2XQ6 A; 3JAE A; 3RIF A; 5AFN A; 3SQ6 A; 5HEJ A; 5IUX A; 2X00 A; 2XQ8 A; 3U8N A; 2BYR A; 2XNU A; 3WTL A; 5BRX A; 2YOE A; 4QH4 A; 1UX2 A; 2VL0 A; 2Y54 A; 4FRR A; 4HQP A; 4IRE A; 3C79 A; 3UU6 A; 2BYN A; 3SH1 A; 4ZK1 A; 3UU8 A; 2C9T A; 5J0Z A; 4ALX A; 3C84 A; 3RQW A; 3P50 A; 5HCJ A; 2WNC A; 3U8L A; 3T4M A; 2ZJV A; 3RIA A; 5JME A; 5LXB A; 5LG3 A; 3UU3 A; 2XYS A; 4F8H A; 3RHW A; 3SIO A; 3WTO A; 3TLU A; 4ZJT A; 5AFM B; 2BG9 C; 4TNW A; 3TLV A; 5AFK A; 4IL4 A; 3U8J A; 2BG9 B; 4AFG A; 5AFJ A; 1I9B A; 2XQ9 A; 4ZZB A; 3TLS A; 2WZY A; 2XQA A; 3WTM A; 4UM1 A; 3JAD A; 5AIN A; 2XZ5 A; 2BYS A; 5AFL A; 2BYQ A; 2WN9 A; 4QH5 A; 3UQ4 A; 3ZDG A; 2WNJ A; 1UV6 A; 4BQT A; 4AFT A; 4XHE A; 3UU4 A; 2ZJU A; 3EI0 A; 4ZJS A; 4HFB A; 2W8G A;
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