1C24A

E. coli methionine aminopeptidase: methionine phosphinate complex
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 88
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c24A00
1QZYA 3TAVA 1B6AA 1YJ3A 4HXXA 5CE6A 1XGNA 3MR1A 2BWWA 5CDEA 1WY2A 2P98A 2P9AA 3FMQA 2V6CA 4IKRA 4PV4A 5CDVA 4S01A 2BN7A 2V3ZA 3BITA 3PKAA 3L7GA 4IKSA 3MATA 2V3YA 2GG9A 2BHDA 2Q93A 4IDYA 3D27A 2GU5A 3PKDA 1QXYA 1MATA 1XGOA 1YW9A 4QR8A 3MX6A 4IF7A 4U6WA 4FLIA 5E5BA 4EGEA 2BB7A 1C27A 2B3LA 1CHMA 1M35A 2BWSA 1QXZA 4RZZA 4FUKA 2BHCA 1C24A 4KM3A 1O0XA 2B3HA 4U6ZA 1WL9A 3FM3A 4ZWPA 5CIKA 3RVAA 3RORA 5FCHA 4U76A 2GU7A 2GG0A 5CNXA 1WBQA 2OKNA 4JUQA 1WLRA 2BHAA 2DFIA 2EVMA 1A16A 3PKEA 2B3KA 4U71A 2GGCA 4U73A 4U75A 1R58A 4IU6A 2ADUA 2EVOA 1C23A 4FLLA 2BWUA 1C22A 1YVMA 3CTZA 2Q8KA 4RGZ1 1R5HA 4U1BA 1XNZA 3Q6DA 2P99A 1YW8A 3S6BA 1C21A 4B28A 1WKMA 2IW2A 3CB6A 4MATA 5D6EA 3PKBA 4U6JA 2BHBA 3IG4A 2Q92A 3PKCA 3FMRA 2GA2A 1WN1A 2GG3A 2HOWA 4U6CA 3L24A 5CLSA 3IU9A 2ZSGA 1N51A 4A6WA 1W7VA 1YW7A 5JFRA 3IU7A 1XGMA 1B59A 1KQ9A 2GU4A 2EVCA 4IKUA 4PNCA 2BWTA 4A6VA 2GGBA 5JHUA 4ZWOA 2GG7A 1PV9A 2G6PA 2NQ7A 4FKCA 4ZNGA 5FCFA 4ZWUA 2MATA 2Q94A 1R5GA 4FLKA 4FLJA 4U70A 2Q95A 2BWXA 2GU6A 2OAZA 4U6EA 1XGSA 2GTXA 2V3XA 2BH3A 3CB5A 4IECA 5JI6A 1Y1NA 1BOAA 2EA4A 2NQ6A 4IKTA 2GG8A 3BIQA 4S2RP 2GG2A 4R60A 4FO7A 3BIPA 4U69A 4FO8A 4S00A 2Q96A 4RZYA 3IU8A 2GG5A 2BWYA 3TB5A 1JAWA 2GZ5A 4OOKA 4S2TP 1KP0A 2EA2A 4IPAA 4Z7MA 1KQ0A 5D6FA 1WL6A 5CDLA 1W2MA 1QXWA 1BN5A 2BWVA
chains in the Genus database with same CATH superfamily
1QZYA 3TAVA 1B6AA 1YJ3A 4HXXA 5CE6A 1XGNA 3MR1A 2BWWA 5CDEA 1WY2A 2P98A 2P9AA 3FMQA 2V6CA 4IKRA 4PV4A 5CDVA 4S01A 2BN7A 2V3ZA 3BITA 3PKAA 3L7GA 4IKSA 3MATA 2V3YA 2GG9A 2BHDA 2Q93A 4IDYA 3D27A 2GU5A 3PKDA 1QXYA 1MATA 1XGOA 1YW9A 4QR8A 3MX6A 4IF7A 4U6WA 4FLIA 5E5BA 4EGEA 2BB7A 1C27A 2B3LA 1CHMA 1M35A 2BWSA 1QXZA 4RZZA 4FUKA 2BHCA 1C24A 4KM3A 1O0XA 2B3HA 4U6ZA 1WL9A 3FM3A 4ZWPA 5CIKA 3RVAA 3RORA 5FCHA 4U76A 2GU7A 2GG0A 5CNXA 1WBQA 2OKNA 4JUQA 1WLRA 2BHAA 2DFIA 2EVMA 1A16A 3PKEA 2B3KA 4U71A 2GGCA 4U73A 4U75A 1R58A 4IU6A 2ADUA 2EVOA 1C23A 4FLLA 2BWUA 1C22A 1YVMA 3CTZA 2Q8KA 4RGZ1 1R5HA 4U1BA 1XNZA 3Q6DA 2P99A 1YW8A 3S6BA 1C21A 4B28A 1WKMA 2IW2A 3CB6A 4MATA 5D6EA 3PKBA 4U6JA 2BHBA 3IG4A 2Q92A 3PKCA 3FMRA 2GA2A 1WN1A 2GG3A 2HOWA 4U6CA 3L24A 5CLSA 3IU9A 2ZSGA 1N51A 4A6WA 1W7VA 1YW7A 5JFRA 3IU7A 1XGMA 1B59A 1KQ9A 2GU4A 2EVCA 4IKUA 4PNCA 2BWTA 4A6VA 2GGBA 5JHUA 4ZWOA 2GG7A 1PV9A 2G6PA 2NQ7A 4FKCA 4ZNGA 5FCFA 4ZWUA 2MATA 2Q94A 1R5GA 4FLKA 4FLJA 4U70A 2Q95A 2BWXA 2GU6A 2OAZA 4U6EA 1XGSA 2GTXA 2V3XA 2BH3A 3CB5A 4IECA 5JI6A 1Y1NA 1BOAA 2EA4A 2NQ6A 4IKTA 2GG8A 3BIQA 4S2RP 2GG2A 4R60A 4FO7A 3BIPA 4U69A 4FO8A 4S00A 2Q96A 4RZYA 3IU8A 2GG5A 2BWYA 3TB5A 1JAWA 2GZ5A 4OOKA 4S2TP 1KP0A 2EA2A 4IPAA 4Z7MA 1KQ0A 5D6FA 1WL6A 5CDLA 1W2MA 1QXWA 1BN5A 2BWVA
chains in the Genus database with same CATH topology
1QZYA 3TAVA 1B6AA 1YJ3A 4HXXA 5CE6A 1XGNA 3MR1A 2BWWA 5CDEA 1WY2A 2P98A 2P9AA 3FMQA 2V6CA 4IKRA 4PV4A 5CDVA 4S01A 2BN7A 2V3ZA 3BITA 3PKAA 3L7GA 4IKSA 3MATA 2V3YA 2GG9A 2BHDA 2Q93A 4IDYA 3D27A 2GU5A 3PKDA 1QXYA 1MATA 1XGOA 1YW9A 4QR8A 3MX6A 4IF7A 4U6WA 4FLIA 5E5BA 4EGEA 2BB7A 1C27A 2B3LA 1CHMA 1M35A 2BWSA 1QXZA 4RZZA 4FUKA 2BHCA 1C24A 4KM3A 1O0XA 2B3HA 4U6ZA 1WL9A 3FM3A 4ZWPA 5CIKA 3RVAA 3RORA 5FCHA 4U76A 2GU7A 2GG0A 5CNXA 1WBQA 2OKNA 4JUQA 1WLRA 2BHAA 2DFIA 2EVMA 1A16A 3PKEA 2B3KA 4U71A 2GGCA 4U73A 4U75A 1R58A 4IU6A 2ADUA 2EVOA 1C23A 4FLLA 2BWUA 1C22A 1YVMA 3CTZA 2Q8KA 4RGZ1 1R5HA 4U1BA 1XNZA 3Q6DA 2P99A 1YW8A 3S6BA 1C21A 4B28A 1WKMA 2IW2A 3CB6A 4MATA 5D6EA 3PKBA 4U6JA 2BHBA 3IG4A 2Q92A 3PKCA 3FMRA 2GA2A 1WN1A 2GG3A 2HOWA 4U6CA 3L24A 5CLSA 3IU9A 2ZSGA 1N51A 4A6WA 1W7VA 1YW7A 5JFRA 3IU7A 1XGMA 1B59A 1KQ9A 2GU4A 2EVCA 4IKUA 4PNCA 2BWTA 4A6VA 2GGBA 5JHUA 4ZWOA 2GG7A 1PV9A 2G6PA 2NQ7A 4FKCA 4ZNGA 5FCFA 4ZWUA 2MATA 2Q94A 1R5GA 4FLKA 4FLJA 4U70A 2Q95A 2BWXA 2GU6A 2OAZA 4U6EA 1XGSA 2GTXA 2V3XA 2BH3A 3CB5A 4IECA 5JI6A 1Y1NA 1BOAA 2EA4A 2NQ6A 4IKTA 2GG8A 3BIQA 4S2RP 2GG2A 4R60A 4FO7A 3BIPA 4U69A 4FO8A 4S00A 2Q96A 4RZYA 3IU8A 2GG5A 2BWYA 3TB5A 1JAWA 2GZ5A 4OOKA 4S2TP 1KP0A 2EA2A 4IPAA 4Z7MA 1KQ0A 5D6FA 1WL6A 5CDLA 1W2MA 1QXWA 1BN5A 2BWVA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QZY A;  3TAV A;  1B6A A;  1YJ3 A;  4HXX A;  5CE6 A;  1XGN A;  3MR1 A;  2BWW A;  5CDE A;  1WY2 A;  2P98 A;  2P9A A;  3FMQ A;  2V6C A;  4IKR A;  4PV4 A;  5CDV A;  4S01 A;  2BN7 A;  2V3Z A;  3BIT A;  3PKA A;  3L7G A;  4IKS A;  3MAT A;  2V3Y A;  2GG9 A;  2BHD A;  2Q93 A;  4IDY A;  3D27 A;  2GU5 A;  3PKD A;  1QXY A;  1MAT A;  1XGO A;  1YW9 A;  4QR8 A;  3MX6 A;  4IF7 A;  4U6W A;  4FLI A;  5E5B A;  4EGE A;  2BB7 A;  1C27 A;  2B3L A;  1CHM A;  1M35 A;  2BWS A;  1QXZ A;  4RZZ A;  4FUK A;  2BHC A;  1C24 A;  4KM3 A;  1O0X A;  2B3H A;  4U6Z A;  1WL9 A;  3FM3 A;  4ZWP A;  5CIK A;  3RVA A;  3ROR A;  5FCH A;  4U76 A;  2GU7 A;  2GG0 A;  5CNX A;  1WBQ A;  2OKN A;  4JUQ A;  1WLR A;  2BHA A;  2DFI A;  2EVM A;  1A16 A;  3PKE A;  2B3K A;  4U71 A;  2GGC A;  4U73 A;  4U75 A;  1R58 A;  4IU6 A;  2ADU A;  2EVO A;  1C23 A;  4FLL A;  2BWU A;  1C22 A;  1YVM A;  3CTZ A;  2Q8K A;  4RGZ 1;  1R5H A;  4U1B A;  1XNZ A;  3Q6D A;  2P99 A;  1YW8 A;  3S6B A;  1C21 A;  4B28 A;  1WKM A;  2IW2 A;  3CB6 A;  4MAT A;  5D6E A;  3PKB A;  4U6J A;  2BHB A;  3IG4 A;  2Q92 A;  3PKC A;  3FMR A;  2GA2 A;  1WN1 A;  2GG3 A;  2HOW A;  4U6C A;  3L24 A;  5CLS A;  3IU9 A;  2ZSG A;  1N51 A;  4A6W A;  1W7V A;  1YW7 A;  5JFR A;  3IU7 A;  1XGM A;  1B59 A;  1KQ9 A;  2GU4 A;  2EVC A;  4IKU A;  4PNC A;  2BWT A;  4A6V A;  2GGB A;  5JHU A;  4ZWO A;  2GG7 A;  1PV9 A;  2G6P A;  2NQ7 A;  4FKC A;  4ZNG A;  5FCF A;  4ZWU A;  2MAT A;  2Q94 A;  1R5G A;  4FLK A;  4FLJ A;  4U70 A;  2Q95 A;  2BWX A;  2GU6 A;  2OAZ A;  4U6E A;  1XGS A;  2GTX A;  2V3X A;  2BH3 A;  3CB5 A;  4IEC A;  5JI6 A;  1Y1N A;  1BOA A;  2EA4 A;  2NQ6 A;  4IKT A;  2GG8 A;  3BIQ A;  4S2R P;  2GG2 A;  4R60 A;  4FO7 A;  3BIP A;  4U69 A;  4FO8 A;  4S00 A;  2Q96 A;  4RZY A;  3IU8 A;  2GG5 A;  2BWY A;  3TB5 A;  1JAW A;  2GZ5 A;  4OOK A;  4S2T P;  1KP0 A;  2EA2 A;  4IPA A;  4Z7M A;  1KQ0 A;  5D6F A;  1WL6 A;  5CDL A;  1W2M A;  1QXW A;  1BN5 A;  2BWV A; 
#chains in the Genus database with same CATH topology
 1QZY A;  3TAV A;  1B6A A;  1YJ3 A;  4HXX A;  5CE6 A;  1XGN A;  3MR1 A;  2BWW A;  5CDE A;  1WY2 A;  2P98 A;  2P9A A;  3FMQ A;  2V6C A;  4IKR A;  4PV4 A;  5CDV A;  4S01 A;  2BN7 A;  2V3Z A;  3BIT A;  3PKA A;  3L7G A;  4IKS A;  3MAT A;  2V3Y A;  2GG9 A;  2BHD A;  2Q93 A;  4IDY A;  3D27 A;  2GU5 A;  3PKD A;  1QXY A;  1MAT A;  1XGO A;  1YW9 A;  4QR8 A;  3MX6 A;  4IF7 A;  4U6W A;  4FLI A;  5E5B A;  4EGE A;  2BB7 A;  1C27 A;  2B3L A;  1CHM A;  1M35 A;  2BWS A;  1QXZ A;  4RZZ A;  4FUK A;  2BHC A;  1C24 A;  4KM3 A;  1O0X A;  2B3H A;  4U6Z A;  1WL9 A;  3FM3 A;  4ZWP A;  5CIK A;  3RVA A;  3ROR A;  5FCH A;  4U76 A;  2GU7 A;  2GG0 A;  5CNX A;  1WBQ A;  2OKN A;  4JUQ A;  1WLR A;  2BHA A;  2DFI A;  2EVM A;  1A16 A;  3PKE A;  2B3K A;  4U71 A;  2GGC A;  4U73 A;  4U75 A;  1R58 A;  4IU6 A;  2ADU A;  2EVO A;  1C23 A;  4FLL A;  2BWU A;  1C22 A;  1YVM A;  3CTZ A;  2Q8K A;  4RGZ 1;  1R5H A;  4U1B A;  1XNZ A;  3Q6D A;  2P99 A;  1YW8 A;  3S6B A;  1C21 A;  4B28 A;  1WKM A;  2IW2 A;  3CB6 A;  4MAT A;  5D6E A;  3PKB A;  4U6J A;  2BHB A;  3IG4 A;  2Q92 A;  3PKC A;  3FMR A;  2GA2 A;  1WN1 A;  2GG3 A;  2HOW A;  4U6C A;  3L24 A;  5CLS A;  3IU9 A;  2ZSG A;  1N51 A;  4A6W A;  1W7V A;  1YW7 A;  5JFR A;  3IU7 A;  1XGM A;  1B59 A;  1KQ9 A;  2GU4 A;  2EVC A;  4IKU A;  4PNC A;  2BWT A;  4A6V A;  2GGB A;  5JHU A;  4ZWO A;  2GG7 A;  1PV9 A;  2G6P A;  2NQ7 A;  4FKC A;  4ZNG A;  5FCF A;  4ZWU A;  2MAT A;  2Q94 A;  1R5G A;  4FLK A;  4FLJ A;  4U70 A;  2Q95 A;  2BWX A;  2GU6 A;  2OAZ A;  4U6E A;  1XGS A;  2GTX A;  2V3X A;  2BH3 A;  3CB5 A;  4IEC A;  5JI6 A;  1Y1N A;  1BOA A;  2EA4 A;  2NQ6 A;  4IKT A;  2GG8 A;  3BIQ A;  4S2R P;  2GG2 A;  4R60 A;  4FO7 A;  3BIP A;  4U69 A;  4FO8 A;  4S00 A;  2Q96 A;  4RZY A;  3IU8 A;  2GG5 A;  2BWY A;  3TB5 A;  1JAW A;  2GZ5 A;  4OOK A;  4S2T P;  1KP0 A;  2EA2 A;  4IPA A;  4Z7M A;  1KQ0 A;  5D6F A;  1WL6 A;  5CDL A;  1W2M A;  1QXW A;  1BN5 A;  2BWV A; 
#chains in the Genus database with same CATH homology
 1QZY A;  3TAV A;  1B6A A;  1YJ3 A;  4HXX A;  5CE6 A;  1XGN A;  3MR1 A;  2BWW A;  5CDE A;  1WY2 A;  2P98 A;  2P9A A;  3FMQ A;  2V6C A;  4IKR A;  4PV4 A;  5CDV A;  4S01 A;  2BN7 A;  2V3Z A;  3BIT A;  3PKA A;  3L7G A;  4IKS A;  3MAT A;  2V3Y A;  2GG9 A;  2BHD A;  2Q93 A;  4IDY A;  3D27 A;  2GU5 A;  3PKD A;  1QXY A;  1MAT A;  1XGO A;  1YW9 A;  4QR8 A;  3MX6 A;  4IF7 A;  4U6W A;  4FLI A;  5E5B A;  4EGE A;  2BB7 A;  1C27 A;  2B3L A;  1CHM A;  1M35 A;  2BWS A;  1QXZ A;  4RZZ A;  4FUK A;  2BHC A;  1C24 A;  4KM3 A;  1O0X A;  2B3H A;  4U6Z A;  1WL9 A;  3FM3 A;  4ZWP A;  5CIK A;  3RVA A;  3ROR A;  5FCH A;  4U76 A;  2GU7 A;  2GG0 A;  5CNX A;  1WBQ A;  2OKN A;  4JUQ A;  1WLR A;  2BHA A;  2DFI A;  2EVM A;  1A16 A;  3PKE A;  2B3K A;  4U71 A;  2GGC A;  4U73 A;  4U75 A;  1R58 A;  4IU6 A;  2ADU A;  2EVO A;  1C23 A;  4FLL A;  2BWU A;  1C22 A;  1YVM A;  3CTZ A;  2Q8K A;  4RGZ 1;  1R5H A;  4U1B A;  1XNZ A;  3Q6D A;  2P99 A;  1YW8 A;  3S6B A;  1C21 A;  4B28 A;  1WKM A;  2IW2 A;  3CB6 A;  4MAT A;  5D6E A;  3PKB A;  4U6J A;  2BHB A;  3IG4 A;  2Q92 A;  3PKC A;  3FMR A;  2GA2 A;  1WN1 A;  2GG3 A;  2HOW A;  4U6C A;  3L24 A;  5CLS A;  3IU9 A;  2ZSG A;  1N51 A;  4A6W A;  1W7V A;  1YW7 A;  5JFR A;  3IU7 A;  1XGM A;  1B59 A;  1KQ9 A;  2GU4 A;  2EVC A;  4IKU A;  4PNC A;  2BWT A;  4A6V A;  2GGB A;  5JHU A;  4ZWO A;  2GG7 A;  1PV9 A;  2G6P A;  2NQ7 A;  4FKC A;  4ZNG A;  5FCF A;  4ZWU A;  2MAT A;  2Q94 A;  1R5G A;  4FLK A;  4FLJ A;  4U70 A;  2Q95 A;  2BWX A;  2GU6 A;  2OAZ A;  4U6E A;  1XGS A;  2GTX A;  2V3X A;  2BH3 A;  3CB5 A;  4IEC A;  5JI6 A;  1Y1N A;  1BOA A;  2EA4 A;  2NQ6 A;  4IKT A;  2GG8 A;  3BIQ A;  4S2R P;  2GG2 A;  4R60 A;  4FO7 A;  3BIP A;  4U69 A;  4FO8 A;  4S00 A;  2Q96 A;  4RZY A;  3IU8 A;  2GG5 A;  2BWY A;  3TB5 A;  1JAW A;  2GZ5 A;  4OOK A;  4S2T P;  1KP0 A;  2EA2 A;  4IPA A;  4Z7M A;  1KQ0 A;  5D6F A;  1WL6 A;  5CDL A;  1W2M A;  1QXW A;  1BN5 A;  2BWV A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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