1C24A

E. coli methionine aminopeptidase: methionine phosphinate complex
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 88
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c24A00
2EA2A 1W7VA 4FKCA 4IECA 3BIPA 4JUQA 3PKAA 1R58A 2MATA 2GG7A 2V6CA 4RZZA 5CDVA 4U6JA 1KQ9A 1XGMA 1R5GA 1WN1A 2EA4A 1BN5A 1CHMA 1WL9A 2B3HA 2BN7A 2GG9A 2GG8A 1WL6A 2P98A 2Q93A 5D6EA 1JAWA 1WBQA 3MR1A 3RVAA 4IU6A 4U71A 5CNXA 1MATA 2GG5A 2BWWA 3MATA 2NQ6A 2BHDA 2EVMA 1B59A 1C22A 1QXYA 3IG4A 4A6VA 2P99A 3CB6A 5FCHA 4S00A 2GTXA 2IW2A 2Q95A 4ZNGA 4Z7MA 1QZYA 1WKMA 3IU9A 1WLRA 1YVMA 2Q94A 4OOKA 3IU8A 2V3ZA 5JHUA 1Y1NA 5D6FA 1C23A 4R60A 4FLIA 1YW9A 4IKTA 4U75A 4U6CA 2GGCA 2ADUA 4EGEA 1XGNA 2B3LA 2GU5A 4FLLA 5CDEA 2BWYA 1KQ0A 3L24A 3TAVA 1B6AA 3L7GA 2BHCA 2Q92A 3CTZA 4S01A 3IU7A 2BHBA 4U73A 4IF7A 4FO7A 4ZWOA 2V3XA 3Q6DA 2GU7A 2GG2A 1M35A 4PNCA 1C24A 4U1BA 4B28A 4QR8A 3FMRA 1PV9A 2GGBA 4S2RP 2BHAA 3S6BA 4MATA 5CLSA 2GG0A 2P9AA 2GU4A 2BB7A 3BITA 4IPAA 5CIKA 2Q8KA 4FO8A 5CDLA 1YJ3A 4U6WA 3PKDA 4IKUA 1N51A 2BWVA 2V3YA 2ZSGA 3CB5A 4RGZ1 2OKNA 4U70A 2NQ7A 4IDYA 5E5BA 4HXXA 1YW7A 1W2MA 3FM3A 1QXWA 1WY2A 5FCFA 4U6ZA 2OAZA 2GG3A 4FLKA 4ZWUA 5CE6A 2GA2A 2BWUA 4FUKA 2GU6A 3D27A 4A6WA 2EVCA 1C27A 4IKSA 4U6EA 5JFRA 3PKBA 4PV4A 2DFIA 4IKRA 1A16A 2B3KA 3PKCA 1XGSA 2G6PA 1R5HA 2GZ5A 4ZWPA 1BOAA 2Q96A 3FMQA 4KM3A 5JI6A 4S2TP 2HOWA 2BWXA 3MX6A 4U76A 3BIQA 4FLJA 1XNZA 3PKEA 1YW8A 4RZYA 2BWTA 4U69A 2BWSA 1XGOA 1O0XA 1C21A 3RORA 1QXZA 2EVOA 3TB5A 1KP0A 2BH3A
chains in the Genus database with same CATH superfamily
2EA2A 1W7VA 4FKCA 4IECA 3BIPA 4JUQA 3PKAA 1R58A 2MATA 2GG7A 2V6CA 4RZZA 5CDVA 4U6JA 1KQ9A 1XGMA 1R5GA 1WN1A 2EA4A 1BN5A 1CHMA 1WL9A 2B3HA 2BN7A 2GG9A 2GG8A 1WL6A 2P98A 2Q93A 5D6EA 1JAWA 1WBQA 3MR1A 3RVAA 4IU6A 4U71A 5CNXA 1MATA 2GG5A 2BWWA 3MATA 2NQ6A 2BHDA 2EVMA 1B59A 1C22A 1QXYA 3IG4A 4A6VA 2P99A 3CB6A 5FCHA 4S00A 2GTXA 2IW2A 2Q95A 4ZNGA 4Z7MA 1QZYA 1WKMA 3IU9A 1WLRA 1YVMA 2Q94A 4OOKA 3IU8A 2V3ZA 5JHUA 1Y1NA 5D6FA 1C23A 4R60A 4FLIA 1YW9A 4IKTA 4U75A 4U6CA 2GGCA 2ADUA 4EGEA 1XGNA 2B3LA 2GU5A 4FLLA 5CDEA 2BWYA 1KQ0A 3L24A 3TAVA 1B6AA 3L7GA 2BHCA 2Q92A 3CTZA 4S01A 3IU7A 2BHBA 4U73A 4IF7A 4FO7A 4ZWOA 2V3XA 3Q6DA 2GU7A 2GG2A 1M35A 4PNCA 1C24A 4U1BA 4B28A 4QR8A 3FMRA 1PV9A 2GGBA 4S2RP 2BHAA 3S6BA 4MATA 5CLSA 2GG0A 2P9AA 2GU4A 2BB7A 3BITA 4IPAA 5CIKA 2Q8KA 4FO8A 5CDLA 1YJ3A 4U6WA 3PKDA 4IKUA 1N51A 2BWVA 2V3YA 2ZSGA 3CB5A 4RGZ1 2OKNA 4U70A 2NQ7A 4IDYA 5E5BA 4HXXA 1YW7A 1W2MA 3FM3A 1QXWA 1WY2A 5FCFA 4U6ZA 2OAZA 2GG3A 4FLKA 4ZWUA 5CE6A 2GA2A 2BWUA 4FUKA 2GU6A 3D27A 4A6WA 2EVCA 1C27A 4IKSA 4U6EA 5JFRA 3PKBA 4PV4A 2DFIA 4IKRA 1A16A 2B3KA 3PKCA 1XGSA 2G6PA 1R5HA 2GZ5A 4ZWPA 1BOAA 2Q96A 3FMQA 4KM3A 5JI6A 4S2TP 2HOWA 2BWXA 3MX6A 4U76A 3BIQA 4FLJA 1XNZA 3PKEA 1YW8A 4RZYA 2BWTA 4U69A 2BWSA 1XGOA 1O0XA 1C21A 3RORA 1QXZA 2EVOA 3TB5A 1KP0A 2BH3A
chains in the Genus database with same CATH topology
2EA2A 1W7VA 4FKCA 4IECA 3BIPA 4JUQA 3PKAA 1R58A 2MATA 2GG7A 2V6CA 4RZZA 5CDVA 4U6JA 1KQ9A 1XGMA 1R5GA 1WN1A 2EA4A 1BN5A 1CHMA 1WL9A 2B3HA 2BN7A 2GG9A 2GG8A 1WL6A 2P98A 2Q93A 5D6EA 1JAWA 1WBQA 3MR1A 3RVAA 4IU6A 4U71A 5CNXA 1MATA 2GG5A 2BWWA 3MATA 2NQ6A 2BHDA 2EVMA 1B59A 1C22A 1QXYA 3IG4A 4A6VA 2P99A 3CB6A 5FCHA 4S00A 2GTXA 2IW2A 2Q95A 4ZNGA 4Z7MA 1QZYA 1WKMA 3IU9A 1WLRA 1YVMA 2Q94A 4OOKA 3IU8A 2V3ZA 5JHUA 1Y1NA 5D6FA 1C23A 4R60A 4FLIA 1YW9A 4IKTA 4U75A 4U6CA 2GGCA 2ADUA 4EGEA 1XGNA 2B3LA 2GU5A 4FLLA 5CDEA 2BWYA 1KQ0A 3L24A 3TAVA 1B6AA 3L7GA 2BHCA 2Q92A 3CTZA 4S01A 3IU7A 2BHBA 4U73A 4IF7A 4FO7A 4ZWOA 2V3XA 3Q6DA 2GU7A 2GG2A 1M35A 4PNCA 1C24A 4U1BA 4B28A 4QR8A 3FMRA 1PV9A 2GGBA 4S2RP 2BHAA 3S6BA 4MATA 5CLSA 2GG0A 2P9AA 2GU4A 2BB7A 3BITA 4IPAA 5CIKA 2Q8KA 4FO8A 5CDLA 1YJ3A 4U6WA 3PKDA 4IKUA 1N51A 2BWVA 2V3YA 2ZSGA 3CB5A 4RGZ1 2OKNA 4U70A 2NQ7A 4IDYA 5E5BA 4HXXA 1YW7A 1W2MA 3FM3A 1QXWA 1WY2A 5FCFA 4U6ZA 2OAZA 2GG3A 4FLKA 4ZWUA 5CE6A 2GA2A 2BWUA 4FUKA 2GU6A 3D27A 4A6WA 2EVCA 1C27A 4IKSA 4U6EA 5JFRA 3PKBA 4PV4A 2DFIA 4IKRA 1A16A 2B3KA 3PKCA 1XGSA 2G6PA 1R5HA 2GZ5A 4ZWPA 1BOAA 2Q96A 3FMQA 4KM3A 5JI6A 4S2TP 2HOWA 2BWXA 3MX6A 4U76A 3BIQA 4FLJA 1XNZA 3PKEA 1YW8A 4RZYA 2BWTA 4U69A 2BWSA 1XGOA 1O0XA 1C21A 3RORA 1QXZA 2EVOA 3TB5A 1KP0A 2BH3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EA2 A;  1W7V A;  4FKC A;  4IEC A;  3BIP A;  4JUQ A;  3PKA A;  1R58 A;  2MAT A;  2GG7 A;  2V6C A;  4RZZ A;  5CDV A;  4U6J A;  1KQ9 A;  1XGM A;  1R5G A;  1WN1 A;  2EA4 A;  1BN5 A;  1CHM A;  1WL9 A;  2B3H A;  2BN7 A;  2GG9 A;  2GG8 A;  1WL6 A;  2P98 A;  2Q93 A;  5D6E A;  1JAW A;  1WBQ A;  3MR1 A;  3RVA A;  4IU6 A;  4U71 A;  5CNX A;  1MAT A;  2GG5 A;  2BWW A;  3MAT A;  2NQ6 A;  2BHD A;  2EVM A;  1B59 A;  1C22 A;  1QXY A;  3IG4 A;  4A6V A;  2P99 A;  3CB6 A;  5FCH A;  4S00 A;  2GTX A;  2IW2 A;  2Q95 A;  4ZNG A;  4Z7M A;  1QZY A;  1WKM A;  3IU9 A;  1WLR A;  1YVM A;  2Q94 A;  4OOK A;  3IU8 A;  2V3Z A;  5JHU A;  1Y1N A;  5D6F A;  1C23 A;  4R60 A;  4FLI A;  1YW9 A;  4IKT A;  4U75 A;  4U6C A;  2GGC A;  2ADU A;  4EGE A;  1XGN A;  2B3L A;  2GU5 A;  4FLL A;  5CDE A;  2BWY A;  1KQ0 A;  3L24 A;  3TAV A;  1B6A A;  3L7G A;  2BHC A;  2Q92 A;  3CTZ A;  4S01 A;  3IU7 A;  2BHB A;  4U73 A;  4IF7 A;  4FO7 A;  4ZWO A;  2V3X A;  3Q6D A;  2GU7 A;  2GG2 A;  1M35 A;  4PNC A;  1C24 A;  4U1B A;  4B28 A;  4QR8 A;  3FMR A;  1PV9 A;  2GGB A;  4S2R P;  2BHA A;  3S6B A;  4MAT A;  5CLS A;  2GG0 A;  2P9A A;  2GU4 A;  2BB7 A;  3BIT A;  4IPA A;  5CIK A;  2Q8K A;  4FO8 A;  5CDL A;  1YJ3 A;  4U6W A;  3PKD A;  4IKU A;  1N51 A;  2BWV A;  2V3Y A;  2ZSG A;  3CB5 A;  4RGZ 1;  2OKN A;  4U70 A;  2NQ7 A;  4IDY A;  5E5B A;  4HXX A;  1YW7 A;  1W2M A;  3FM3 A;  1QXW A;  1WY2 A;  5FCF A;  4U6Z A;  2OAZ A;  2GG3 A;  4FLK A;  4ZWU A;  5CE6 A;  2GA2 A;  2BWU A;  4FUK A;  2GU6 A;  3D27 A;  4A6W A;  2EVC A;  1C27 A;  4IKS A;  4U6E A;  5JFR A;  3PKB A;  4PV4 A;  2DFI A;  4IKR A;  1A16 A;  2B3K A;  3PKC A;  1XGS A;  2G6P A;  1R5H A;  2GZ5 A;  4ZWP A;  1BOA A;  2Q96 A;  3FMQ A;  4KM3 A;  5JI6 A;  4S2T P;  2HOW A;  2BWX A;  3MX6 A;  4U76 A;  3BIQ A;  4FLJ A;  1XNZ A;  3PKE A;  1YW8 A;  4RZY A;  2BWT A;  4U69 A;  2BWS A;  1XGO A;  1O0X A;  1C21 A;  3ROR A;  1QXZ A;  2EVO A;  3TB5 A;  1KP0 A;  2BH3 A; 
#chains in the Genus database with same CATH topology
 2EA2 A;  1W7V A;  4FKC A;  4IEC A;  3BIP A;  4JUQ A;  3PKA A;  1R58 A;  2MAT A;  2GG7 A;  2V6C A;  4RZZ A;  5CDV A;  4U6J A;  1KQ9 A;  1XGM A;  1R5G A;  1WN1 A;  2EA4 A;  1BN5 A;  1CHM A;  1WL9 A;  2B3H A;  2BN7 A;  2GG9 A;  2GG8 A;  1WL6 A;  2P98 A;  2Q93 A;  5D6E A;  1JAW A;  1WBQ A;  3MR1 A;  3RVA A;  4IU6 A;  4U71 A;  5CNX A;  1MAT A;  2GG5 A;  2BWW A;  3MAT A;  2NQ6 A;  2BHD A;  2EVM A;  1B59 A;  1C22 A;  1QXY A;  3IG4 A;  4A6V A;  2P99 A;  3CB6 A;  5FCH A;  4S00 A;  2GTX A;  2IW2 A;  2Q95 A;  4ZNG A;  4Z7M A;  1QZY A;  1WKM A;  3IU9 A;  1WLR A;  1YVM A;  2Q94 A;  4OOK A;  3IU8 A;  2V3Z A;  5JHU A;  1Y1N A;  5D6F A;  1C23 A;  4R60 A;  4FLI A;  1YW9 A;  4IKT A;  4U75 A;  4U6C A;  2GGC A;  2ADU A;  4EGE A;  1XGN A;  2B3L A;  2GU5 A;  4FLL A;  5CDE A;  2BWY A;  1KQ0 A;  3L24 A;  3TAV A;  1B6A A;  3L7G A;  2BHC A;  2Q92 A;  3CTZ A;  4S01 A;  3IU7 A;  2BHB A;  4U73 A;  4IF7 A;  4FO7 A;  4ZWO A;  2V3X A;  3Q6D A;  2GU7 A;  2GG2 A;  1M35 A;  4PNC A;  1C24 A;  4U1B A;  4B28 A;  4QR8 A;  3FMR A;  1PV9 A;  2GGB A;  4S2R P;  2BHA A;  3S6B A;  4MAT A;  5CLS A;  2GG0 A;  2P9A A;  2GU4 A;  2BB7 A;  3BIT A;  4IPA A;  5CIK A;  2Q8K A;  4FO8 A;  5CDL A;  1YJ3 A;  4U6W A;  3PKD A;  4IKU A;  1N51 A;  2BWV A;  2V3Y A;  2ZSG A;  3CB5 A;  4RGZ 1;  2OKN A;  4U70 A;  2NQ7 A;  4IDY A;  5E5B A;  4HXX A;  1YW7 A;  1W2M A;  3FM3 A;  1QXW A;  1WY2 A;  5FCF A;  4U6Z A;  2OAZ A;  2GG3 A;  4FLK A;  4ZWU A;  5CE6 A;  2GA2 A;  2BWU A;  4FUK A;  2GU6 A;  3D27 A;  4A6W A;  2EVC A;  1C27 A;  4IKS A;  4U6E A;  5JFR A;  3PKB A;  4PV4 A;  2DFI A;  4IKR A;  1A16 A;  2B3K A;  3PKC A;  1XGS A;  2G6P A;  1R5H A;  2GZ5 A;  4ZWP A;  1BOA A;  2Q96 A;  3FMQ A;  4KM3 A;  5JI6 A;  4S2T P;  2HOW A;  2BWX A;  3MX6 A;  4U76 A;  3BIQ A;  4FLJ A;  1XNZ A;  3PKE A;  1YW8 A;  4RZY A;  2BWT A;  4U69 A;  2BWS A;  1XGO A;  1O0X A;  1C21 A;  3ROR A;  1QXZ A;  2EVO A;  3TB5 A;  1KP0 A;  2BH3 A; 
#chains in the Genus database with same CATH homology
 2EA2 A;  1W7V A;  4FKC A;  4IEC A;  3BIP A;  4JUQ A;  3PKA A;  1R58 A;  2MAT A;  2GG7 A;  2V6C A;  4RZZ A;  5CDV A;  4U6J A;  1KQ9 A;  1XGM A;  1R5G A;  1WN1 A;  2EA4 A;  1BN5 A;  1CHM A;  1WL9 A;  2B3H A;  2BN7 A;  2GG9 A;  2GG8 A;  1WL6 A;  2P98 A;  2Q93 A;  5D6E A;  1JAW A;  1WBQ A;  3MR1 A;  3RVA A;  4IU6 A;  4U71 A;  5CNX A;  1MAT A;  2GG5 A;  2BWW A;  3MAT A;  2NQ6 A;  2BHD A;  2EVM A;  1B59 A;  1C22 A;  1QXY A;  3IG4 A;  4A6V A;  2P99 A;  3CB6 A;  5FCH A;  4S00 A;  2GTX A;  2IW2 A;  2Q95 A;  4ZNG A;  4Z7M A;  1QZY A;  1WKM A;  3IU9 A;  1WLR A;  1YVM A;  2Q94 A;  4OOK A;  3IU8 A;  2V3Z A;  5JHU A;  1Y1N A;  5D6F A;  1C23 A;  4R60 A;  4FLI A;  1YW9 A;  4IKT A;  4U75 A;  4U6C A;  2GGC A;  2ADU A;  4EGE A;  1XGN A;  2B3L A;  2GU5 A;  4FLL A;  5CDE A;  2BWY A;  1KQ0 A;  3L24 A;  3TAV A;  1B6A A;  3L7G A;  2BHC A;  2Q92 A;  3CTZ A;  4S01 A;  3IU7 A;  2BHB A;  4U73 A;  4IF7 A;  4FO7 A;  4ZWO A;  2V3X A;  3Q6D A;  2GU7 A;  2GG2 A;  1M35 A;  4PNC A;  1C24 A;  4U1B A;  4B28 A;  4QR8 A;  3FMR A;  1PV9 A;  2GGB A;  4S2R P;  2BHA A;  3S6B A;  4MAT A;  5CLS A;  2GG0 A;  2P9A A;  2GU4 A;  2BB7 A;  3BIT A;  4IPA A;  5CIK A;  2Q8K A;  4FO8 A;  5CDL A;  1YJ3 A;  4U6W A;  3PKD A;  4IKU A;  1N51 A;  2BWV A;  2V3Y A;  2ZSG A;  3CB5 A;  4RGZ 1;  2OKN A;  4U70 A;  2NQ7 A;  4IDY A;  5E5B A;  4HXX A;  1YW7 A;  1W2M A;  3FM3 A;  1QXW A;  1WY2 A;  5FCF A;  4U6Z A;  2OAZ A;  2GG3 A;  4FLK A;  4ZWU A;  5CE6 A;  2GA2 A;  2BWU A;  4FUK A;  2GU6 A;  3D27 A;  4A6W A;  2EVC A;  1C27 A;  4IKS A;  4U6E A;  5JFR A;  3PKB A;  4PV4 A;  2DFI A;  4IKR A;  1A16 A;  2B3K A;  3PKC A;  1XGS A;  2G6P A;  1R5H A;  2GZ5 A;  4ZWP A;  1BOA A;  2Q96 A;  3FMQ A;  4KM3 A;  5JI6 A;  4S2T P;  2HOW A;  2BWX A;  3MX6 A;  4U76 A;  3BIQ A;  4FLJ A;  1XNZ A;  3PKE A;  1YW8 A;  4RZY A;  2BWT A;  4U69 A;  2BWS A;  1XGO A;  1O0X A;  1C21 A;  3ROR A;  1QXZ A;  2EVO A;  3TB5 A;  1KP0 A;  2BH3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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