1PV9A

Prolidase from pyrococcus furiosus
Total Genus 112
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
338
structure length
337
Chain Sequence
LVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGGYIIVDGDEATLYVPELEYEMAKEESKLPVVKFKKFDEIYEILKNTETLGIEGTLSYSMVENFKEKSVKEFKKIDDVIKDLRIIKTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLEIHEWPRISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLITENGAKRLTKTER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
publication title Structure of the Prolidase from Pyrococcus furiosus.
pubmed doi rcsb
source organism Pyrococcus furiosus
total genus 112
structure length 337
sequence length 338
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1pv9A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1pv9A02
4U76A 1MATA 1XGOA 2BWUA 4RZYA 2BWWA 1B59A 1BN5A 2BHBA 1XNZA 4PV4A 1KP0A 4IECA 5E5BA 5CDLA 3MR1A 4IDYA 4B28A 1R5GA 4U69A 4EGEA 3FM3A 2BB7A 2ZSGA 2GG5A 4U71A 3Q6DA 1CHMA 2BWTA 1QXWA 2B3LA 4A6WA 2OAZA 5FCHA 3D27A 3OOOA 3IU8A 1R5HA 2BH3A 2V3ZA 3IU7A 2Q93A 4RZZA 3CTZA 3TAVA 4U6CA 5JFRA 2OKNA 3FMQA 3IU9A 4IF7A 2BN7A 4QR8A 1Y1NA 4U73A 2B3HA 2GGCA 4U6JA 1WLRA 2HOWA 4OOKA 4U6ZA 1XGSA 3FMRA 3IL0A 2GU4A 2GA2A 1PV9A 4Z7MA 1QXYA 4HXXA 1QXZA 2Q95A 4FO8A 2GG9A 3O5VA 1N51A 4S2RP 3PKDA 2ADUA 5JI6A 1XGMA 1C27A 4U75A 3BITA 2NQ7A 3CB5A 4PNCA 1C24A 2MATA 2BWSA 4KM3A 3S6BA 2G6PA 2Q92A 5E2CA 3BIPA 2P9AA 4U6WA 2GU7A 1WL9A 3CB6A 4S01A 1WY2A 1O0XA 1YVMA 1QZYA 4IKRA 2GZ5A 1WN1A 5CDEA 4IU6A 2IW2A 4U1BA 4U6EA 2Q8KA 4FO7A 1WL6A 3I7MA 2BHDA 2BWYA 2EA2A 2V6CA 2GG3A 4FUKA 1YJ3A 2BWXA 1W2MA 2GG7A 4MATA 2V3XA 4A6VA 3PEBA 2P99A 5D6FA 5CIKA 4RGZ1 2Q96A 2EVMA 1C21A 1KQ9A 1C22A 4ZWPA 5CNXA 2BHAA 5FCFA 5CLSA 4IPAA 4JUQA 1R58A 2NQ6A 3PKAA 4R60A 1BOAA 3PKCA 3L24A 3RVAA 3PN9A 5CDVA 1WKMA 1XGNA 4FLLA 4ZWUA 4FLKA 4IKSA 2GG2A 1YW7A 2GG8A 3QOCA 2GU5A 2V3YA 2EA4A 2GG0A 4S00A 5CE6A 2GU6A 4FKCA 3PKEA 1KQ0A 2DFIA 3L7GA 3OVKA 2Q94A 4ZWOA 3BIQA 5JHUA 2P98A 2GTXA 4FLIA 4FLJA 3TB5A 1B6AA 1W7VA 3IG4A 4U70A 1WBQA 1C23A 3MX6A 4IKUA 2EVCA 4IKTA 1M35A 2GGBA 1A16A 4S2TP 2EVOA 5D6EA 3RORA 2BHCA 3MATA 4ZNGA 1YW8A 2BWVA 2B3KA 3PKBA 1JAWA 1YW9A
chains in the Genus database with same CATH superfamily
4U76A 1MATA 1XGOA 2BWUA 4RZYA 2BWWA 1B59A 1BN5A 2BHBA 1XNZA 4PV4A 1KP0A 4IECA 5E5BA 5CDLA 3MR1A 4IDYA 4B28A 1R5GA 4U69A 4EGEA 3FM3A 2BB7A 2ZSGA 2GG5A 4U71A 3Q6DA 1CHMA 2BWTA 1QXWA 2B3LA 4A6WA 2OAZA 5FCHA 3D27A 3OOOA 3IU8A 1R5HA 2BH3A 2V3ZA 3IU7A 2Q93A 4RZZA 3CTZA 3TAVA 4U6CA 5JFRA 2OKNA 3FMQA 3IU9A 4IF7A 2BN7A 4QR8A 1Y1NA 4U73A 2B3HA 2GGCA 4U6JA 1WLRA 2HOWA 4OOKA 4U6ZA 1XGSA 3FMRA 3IL0A 2GU4A 2GA2A 1PV9A 4Z7MA 1QXYA 4HXXA 1QXZA 2Q95A 4FO8A 2GG9A 3O5VA 1N51A 4S2RP 3PKDA 2ADUA 5JI6A 1XGMA 1C27A 4U75A 3BITA 2NQ7A 3CB5A 4PNCA 1C24A 2MATA 2BWSA 4KM3A 3S6BA 2G6PA 2Q92A 5E2CA 3BIPA 2P9AA 4U6WA 2GU7A 1WL9A 3CB6A 4S01A 1WY2A 1O0XA 1YVMA 1QZYA 4IKRA 2GZ5A 1WN1A 5CDEA 4IU6A 2IW2A 4U1BA 4U6EA 2Q8KA 4FO7A 1WL6A 3I7MA 2BHDA 2BWYA 2EA2A 2V6CA 2GG3A 4FUKA 1YJ3A 2BWXA 1W2MA 2GG7A 4MATA 2V3XA 4A6VA 3PEBA 2P99A 5D6FA 5CIKA 4RGZ1 2Q96A 2EVMA 1C21A 1KQ9A 1C22A 4ZWPA 5CNXA 2BHAA 5FCFA 5CLSA 4IPAA 4JUQA 1R58A 2NQ6A 3PKAA 4R60A 1BOAA 3PKCA 3L24A 3RVAA 3PN9A 5CDVA 1WKMA 1XGNA 4FLLA 4ZWUA 4FLKA 4IKSA 2GG2A 1YW7A 2GG8A 3QOCA 2GU5A 2V3YA 2EA4A 2GG0A 4S00A 5CE6A 2GU6A 4FKCA 3PKEA 1KQ0A 2DFIA 3L7GA 3OVKA 2Q94A 4ZWOA 3BIQA 5JHUA 2P98A 2GTXA 4FLIA 4FLJA 3TB5A 1B6AA 1W7VA 3IG4A 4U70A 1WBQA 1C23A 3MX6A 4IKUA 2EVCA 4IKTA 1M35A 2GGBA 1A16A 4S2TP 2EVOA 5D6EA 3RORA 2BHCA 3MATA 4ZNGA 1YW8A 2BWVA 2B3KA 3PKBA 1JAWA 1YW9A
chains in the Genus database with same CATH topology
4U76A 1MATA 1XGOA 2BWUA 4RZYA 2BWWA 1B59A 1BN5A 2BHBA 1XNZA 4PV4A 1KP0A 4IECA 5E5BA 5CDLA 3MR1A 4IDYA 4B28A 1R5GA 4U69A 4EGEA 3FM3A 2BB7A 2ZSGA 2GG5A 4U71A 3Q6DA 1CHMA 2BWTA 1QXWA 2B3LA 4A6WA 2OAZA 5FCHA 3D27A 3OOOA 3IU8A 1R5HA 2BH3A 2V3ZA 3IU7A 2Q93A 4RZZA 3CTZA 3TAVA 4U6CA 5JFRA 2OKNA 3FMQA 3IU9A 4IF7A 2BN7A 4QR8A 1Y1NA 4U73A 2B3HA 2GGCA 4U6JA 1WLRA 2HOWA 4OOKA 4U6ZA 1XGSA 3FMRA 3IL0A 2GU4A 2GA2A 1PV9A 4Z7MA 1QXYA 4HXXA 1QXZA 2Q95A 4FO8A 2GG9A 3O5VA 1N51A 4S2RP 3PKDA 2ADUA 5JI6A 1XGMA 1C27A 4U75A 3BITA 2NQ7A 3CB5A 4PNCA 1C24A 2MATA 2BWSA 4KM3A 3S6BA 2G6PA 2Q92A 5E2CA 3BIPA 2P9AA 4U6WA 2GU7A 1WL9A 3CB6A 4S01A 1WY2A 1O0XA 1YVMA 1QZYA 4IKRA 2GZ5A 1WN1A 5CDEA 4IU6A 2IW2A 4U1BA 4U6EA 2Q8KA 4FO7A 1WL6A 3I7MA 2BHDA 2BWYA 2EA2A 2V6CA 2GG3A 4FUKA 1YJ3A 2BWXA 1W2MA 2GG7A 4MATA 2V3XA 4A6VA 3PEBA 2P99A 5D6FA 5CIKA 4RGZ1 2Q96A 2EVMA 1C21A 1KQ9A 1C22A 4ZWPA 5CNXA 2BHAA 5FCFA 5CLSA 4IPAA 4JUQA 1R58A 2NQ6A 3PKAA 4R60A 1BOAA 3PKCA 3L24A 3RVAA 3PN9A 5CDVA 1WKMA 1XGNA 4FLLA 4ZWUA 4FLKA 4IKSA 2GG2A 1YW7A 2GG8A 3QOCA 2GU5A 2V3YA 2EA4A 2GG0A 4S00A 5CE6A 2GU6A 4FKCA 3PKEA 1KQ0A 2DFIA 3L7GA 3OVKA 2Q94A 4ZWOA 3BIQA 5JHUA 2P98A 2GTXA 4FLIA 4FLJA 3TB5A 1B6AA 1W7VA 3IG4A 4U70A 1WBQA 1C23A 3MX6A 4IKUA 2EVCA 4IKTA 1M35A 2GGBA 1A16A 4S2TP 2EVOA 5D6EA 3RORA 2BHCA 3MATA 4ZNGA 1YW8A 2BWVA 2B3KA 3PKBA 1JAWA 1YW9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U76 A;  1MAT A;  1XGO A;  2BWU A;  4RZY A;  2BWW A;  1B59 A;  1BN5 A;  2BHB A;  1XNZ A;  4PV4 A;  1KP0 A;  4IEC A;  5E5B A;  5CDL A;  3MR1 A;  4IDY A;  4B28 A;  1R5G A;  4U69 A;  4EGE A;  3FM3 A;  2BB7 A;  2ZSG A;  2GG5 A;  4U71 A;  3Q6D A;  1CHM A;  2BWT A;  1QXW A;  2B3L A;  4A6W A;  2OAZ A;  5FCH A;  3D27 A;  3OOO A;  3IU8 A;  1R5H A;  2BH3 A;  2V3Z A;  3IU7 A;  2Q93 A;  4RZZ A;  3CTZ A;  3TAV A;  4U6C A;  5JFR A;  2OKN A;  3FMQ A;  3IU9 A;  4IF7 A;  2BN7 A;  4QR8 A;  1Y1N A;  4U73 A;  2B3H A;  2GGC A;  4U6J A;  1WLR A;  2HOW A;  4OOK A;  4U6Z A;  1XGS A;  3FMR A;  3IL0 A;  2GU4 A;  2GA2 A;  1PV9 A;  4Z7M A;  1QXY A;  4HXX A;  1QXZ A;  2Q95 A;  4FO8 A;  2GG9 A;  3O5V A;  1N51 A;  4S2R P;  3PKD A;  2ADU A;  5JI6 A;  1XGM A;  1C27 A;  4U75 A;  3BIT A;  2NQ7 A;  3CB5 A;  4PNC A;  1C24 A;  2MAT A;  2BWS A;  4KM3 A;  3S6B A;  2G6P A;  2Q92 A;  5E2C A;  3BIP A;  2P9A A;  4U6W A;  2GU7 A;  1WL9 A;  3CB6 A;  4S01 A;  1WY2 A;  1O0X A;  1YVM A;  1QZY A;  4IKR A;  2GZ5 A;  1WN1 A;  5CDE A;  4IU6 A;  2IW2 A;  4U1B A;  4U6E A;  2Q8K A;  4FO7 A;  1WL6 A;  3I7M A;  2BHD A;  2BWY A;  2EA2 A;  2V6C A;  2GG3 A;  4FUK A;  1YJ3 A;  2BWX A;  1W2M A;  2GG7 A;  4MAT A;  2V3X A;  4A6V A;  3PEB A;  2P99 A;  5D6F A;  5CIK A;  4RGZ 1;  2Q96 A;  2EVM A;  1C21 A;  1KQ9 A;  1C22 A;  4ZWP A;  5CNX A;  2BHA A;  5FCF A;  5CLS A;  4IPA A;  4JUQ A;  1R58 A;  2NQ6 A;  3PKA A;  4R60 A;  1BOA A;  3PKC A;  3L24 A;  3RVA A;  3PN9 A;  5CDV A;  1WKM A;  1XGN A;  4FLL A;  4ZWU A;  4FLK A;  4IKS A;  2GG2 A;  1YW7 A;  2GG8 A;  3QOC A;  2GU5 A;  2V3Y A;  2EA4 A;  2GG0 A;  4S00 A;  5CE6 A;  2GU6 A;  4FKC A;  3PKE A;  1KQ0 A;  2DFI A;  3L7G A;  3OVK A;  2Q94 A;  4ZWO A;  3BIQ A;  5JHU A;  2P98 A;  2GTX A;  4FLI A;  4FLJ A;  3TB5 A;  1B6A A;  1W7V A;  3IG4 A;  4U70 A;  1WBQ A;  1C23 A;  3MX6 A;  4IKU A;  2EVC A;  4IKT A;  1M35 A;  2GGB A;  1A16 A;  4S2T P;  2EVO A;  5D6E A;  3ROR A;  2BHC A;  3MAT A;  4ZNG A;  1YW8 A;  2BWV A;  2B3K A;  3PKB A;  1JAW A;  1YW9 A; 
#chains in the Genus database with same CATH topology
 4U76 A;  1MAT A;  1XGO A;  2BWU A;  4RZY A;  2BWW A;  1B59 A;  1BN5 A;  2BHB A;  1XNZ A;  4PV4 A;  1KP0 A;  4IEC A;  5E5B A;  5CDL A;  3MR1 A;  4IDY A;  4B28 A;  1R5G A;  4U69 A;  4EGE A;  3FM3 A;  2BB7 A;  2ZSG A;  2GG5 A;  4U71 A;  3Q6D A;  1CHM A;  2BWT A;  1QXW A;  2B3L A;  4A6W A;  2OAZ A;  5FCH A;  3D27 A;  3OOO A;  3IU8 A;  1R5H A;  2BH3 A;  2V3Z A;  3IU7 A;  2Q93 A;  4RZZ A;  3CTZ A;  3TAV A;  4U6C A;  5JFR A;  2OKN A;  3FMQ A;  3IU9 A;  4IF7 A;  2BN7 A;  4QR8 A;  1Y1N A;  4U73 A;  2B3H A;  2GGC A;  4U6J A;  1WLR A;  2HOW A;  4OOK A;  4U6Z A;  1XGS A;  3FMR A;  3IL0 A;  2GU4 A;  2GA2 A;  1PV9 A;  4Z7M A;  1QXY A;  4HXX A;  1QXZ A;  2Q95 A;  4FO8 A;  2GG9 A;  3O5V A;  1N51 A;  4S2R P;  3PKD A;  2ADU A;  5JI6 A;  1XGM A;  1C27 A;  4U75 A;  3BIT A;  2NQ7 A;  3CB5 A;  4PNC A;  1C24 A;  2MAT A;  2BWS A;  4KM3 A;  3S6B A;  2G6P A;  2Q92 A;  5E2C A;  3BIP A;  2P9A A;  4U6W A;  2GU7 A;  1WL9 A;  3CB6 A;  4S01 A;  1WY2 A;  1O0X A;  1YVM A;  1QZY A;  4IKR A;  2GZ5 A;  1WN1 A;  5CDE A;  4IU6 A;  2IW2 A;  4U1B A;  4U6E A;  2Q8K A;  4FO7 A;  1WL6 A;  3I7M A;  2BHD A;  2BWY A;  2EA2 A;  2V6C A;  2GG3 A;  4FUK A;  1YJ3 A;  2BWX A;  1W2M A;  2GG7 A;  4MAT A;  2V3X A;  4A6V A;  3PEB A;  2P99 A;  5D6F A;  5CIK A;  4RGZ 1;  2Q96 A;  2EVM A;  1C21 A;  1KQ9 A;  1C22 A;  4ZWP A;  5CNX A;  2BHA A;  5FCF A;  5CLS A;  4IPA A;  4JUQ A;  1R58 A;  2NQ6 A;  3PKA A;  4R60 A;  1BOA A;  3PKC A;  3L24 A;  3RVA A;  3PN9 A;  5CDV A;  1WKM A;  1XGN A;  4FLL A;  4ZWU A;  4FLK A;  4IKS A;  2GG2 A;  1YW7 A;  2GG8 A;  3QOC A;  2GU5 A;  2V3Y A;  2EA4 A;  2GG0 A;  4S00 A;  5CE6 A;  2GU6 A;  4FKC A;  3PKE A;  1KQ0 A;  2DFI A;  3L7G A;  3OVK A;  2Q94 A;  4ZWO A;  3BIQ A;  5JHU A;  2P98 A;  2GTX A;  4FLI A;  4FLJ A;  3TB5 A;  1B6A A;  1W7V A;  3IG4 A;  4U70 A;  1WBQ A;  1C23 A;  3MX6 A;  4IKU A;  2EVC A;  4IKT A;  1M35 A;  2GGB A;  1A16 A;  4S2T P;  2EVO A;  5D6E A;  3ROR A;  2BHC A;  3MAT A;  4ZNG A;  1YW8 A;  2BWV A;  2B3K A;  3PKB A;  1JAW A;  1YW9 A; 
#chains in the Genus database with same CATH homology
 4U76 A;  1MAT A;  1XGO A;  2BWU A;  4RZY A;  2BWW A;  1B59 A;  1BN5 A;  2BHB A;  1XNZ A;  4PV4 A;  1KP0 A;  4IEC A;  5E5B A;  5CDL A;  3MR1 A;  4IDY A;  4B28 A;  1R5G A;  4U69 A;  4EGE A;  3FM3 A;  2BB7 A;  2ZSG A;  2GG5 A;  4U71 A;  3Q6D A;  1CHM A;  2BWT A;  1QXW A;  2B3L A;  4A6W A;  2OAZ A;  5FCH A;  3D27 A;  3OOO A;  3IU8 A;  1R5H A;  2BH3 A;  2V3Z A;  3IU7 A;  2Q93 A;  4RZZ A;  3CTZ A;  3TAV A;  4U6C A;  5JFR A;  2OKN A;  3FMQ A;  3IU9 A;  4IF7 A;  2BN7 A;  4QR8 A;  1Y1N A;  4U73 A;  2B3H A;  2GGC A;  4U6J A;  1WLR A;  2HOW A;  4OOK A;  4U6Z A;  1XGS A;  3FMR A;  3IL0 A;  2GU4 A;  2GA2 A;  1PV9 A;  4Z7M A;  1QXY A;  4HXX A;  1QXZ A;  2Q95 A;  4FO8 A;  2GG9 A;  3O5V A;  1N51 A;  4S2R P;  3PKD A;  2ADU A;  5JI6 A;  1XGM A;  1C27 A;  4U75 A;  3BIT A;  2NQ7 A;  3CB5 A;  4PNC A;  1C24 A;  2MAT A;  2BWS A;  4KM3 A;  3S6B A;  2G6P A;  2Q92 A;  5E2C A;  3BIP A;  2P9A A;  4U6W A;  2GU7 A;  1WL9 A;  3CB6 A;  4S01 A;  1WY2 A;  1O0X A;  1YVM A;  1QZY A;  4IKR A;  2GZ5 A;  1WN1 A;  5CDE A;  4IU6 A;  2IW2 A;  4U1B A;  4U6E A;  2Q8K A;  4FO7 A;  1WL6 A;  3I7M A;  2BHD A;  2BWY A;  2EA2 A;  2V6C A;  2GG3 A;  4FUK A;  1YJ3 A;  2BWX A;  1W2M A;  2GG7 A;  4MAT A;  2V3X A;  4A6V A;  3PEB A;  2P99 A;  5D6F A;  5CIK A;  4RGZ 1;  2Q96 A;  2EVM A;  1C21 A;  1KQ9 A;  1C22 A;  4ZWP A;  5CNX A;  2BHA A;  5FCF A;  5CLS A;  4IPA A;  4JUQ A;  1R58 A;  2NQ6 A;  3PKA A;  4R60 A;  1BOA A;  3PKC A;  3L24 A;  3RVA A;  3PN9 A;  5CDV A;  1WKM A;  1XGN A;  4FLL A;  4ZWU A;  4FLK A;  4IKS A;  2GG2 A;  1YW7 A;  2GG8 A;  3QOC A;  2GU5 A;  2V3Y A;  2EA4 A;  2GG0 A;  4S00 A;  5CE6 A;  2GU6 A;  4FKC A;  3PKE A;  1KQ0 A;  2DFI A;  3L7G A;  3OVK A;  2Q94 A;  4ZWO A;  3BIQ A;  5JHU A;  2P98 A;  2GTX A;  4FLI A;  4FLJ A;  3TB5 A;  1B6A A;  1W7V A;  3IG4 A;  4U70 A;  1WBQ A;  1C23 A;  3MX6 A;  4IKU A;  2EVC A;  4IKT A;  1M35 A;  2GGB A;  1A16 A;  4S2T P;  2EVO A;  5D6E A;  3ROR A;  2BHC A;  3MAT A;  4ZNG A;  1YW8 A;  2BWV A;  2B3K A;  3PKB A;  1JAW A;  1YW9 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...