1PV9A

Prolidase from pyrococcus furiosus
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
338
structure length
337
Chain Sequence
LVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGGYIIVDGDEATLYVPELEYEMAKEESKLPVVKFKKFDEIYEILKNTETLGIEGTLSYSMVENFKEKSVKEFKKIDDVIKDLRIIKTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLEIHEWPRISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLITENGAKRLTKTER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the Prolidase from Pyrococcus furiosus.
pubmed doi rcsb
source organism Pyrococcus furiosus
molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
total genus 112
structure length 337
sequence length 338
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1pv9A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1pv9A02
4Z7MA 4U1BA 5D6FA 2P98A 5CDLA 2GG7A 3PKBA 4R60A 2BWYA 2V3ZA 3BIPA 3FM3A 1CHMA 2BH3A 4RZZA 2BWTA 5JI6A 3IL0A 4S01A 1B59A 2NQ7A 3IU9A 4PNCA 2EA4A 4U69A 2HOWA 3D27A 1YVMA 4IDYA 1WBQA 1WKMA 4FO7A 4IKTA 4FLJA 3CB6A 5FCHA 4QR8A 1BN5A 1YW9A 3TAVA 2ADUA 2MATA 3BIQA 5D6EA 4FO8A 4OOKA 2GG2A 3PEBA 3RVAA 3IU8A 4RGZ1 3PKDA 2GU7A 2BWXA 1C27A 1R58A 4U76A 4A6VA 1YW8A 3PKCA 3O5VA 3OOOA 2DFIA 4U6WA 1QXWA 2GG0A 2B3KA 1WL6A 5CLSA 4S00A 5CIKA 3RORA 2BHDA 1R5HA 4FLLA 4U6JA 1XGOA 1WY2A 2GU4A 2EVCA 2EVMA 2Q92A 2GG5A 3L24A 4ZWOA 5CDVA 2ZSGA 2BWSA 4ZWUA 4EGEA 1WLRA 1XNZA 1BOAA 2OAZA 2G6PA 1N51A 4FLKA 4FUKA 5E2CA 2BHBA 5CDEA 1KQ9A 4MATA 2BWWA 2GU6A 4ZWPA 3S6BA 3MX6A 2B3LA 4JUQA 2NQ6A 2P99A 4A6WA 1MATA 1QZYA 4IECA 2GG3A 3QOCA 2Q96A 1O0XA 5CE6A 1C22A 2P9AA 2Q94A 2GU5A 1WN1A 5CNXA 1KQ0A 3PKEA 2BHCA 2BB7A 2BWUA 2GA2A 4RZYA 4U71A 1M35A 4FKCA 2EA2A 1Y1NA 2GGCA 1C24A 1PV9A 3BITA 1WL9A 2IW2A 2GTXA 3FMRA 4U6EA 1YW7A 4HXXA 4KM3A 2V3YA 4IKRA 2BN7A 3CB5A 4S2TP 4IU6A 1W2MA 4PV4A 2GG8A 1B6AA 4S2RP 5FCFA 4IKSA 3CTZA 2Q93A 3MATA 3TB5A 3L7GA 2B3HA 2GG9A 4IPAA 1C23A 2BWVA 1XGNA 3PKAA 4U70A 1W7VA 1QXYA 5E5BA 2EVOA 2GZ5A 4IKUA 2OKNA 2Q95A 3OVKA 4FLIA 4B28A 4U75A 3FMQA 1C21A 5JFRA 4IF7A 2V3XA 4U6ZA 1JAWA 4U73A 1QXZA 2BHAA 3I7MA 5JHUA 2GGBA 1A16A 1XGMA 2Q8KA 1KP0A 1YJ3A 2V6CA 3PN9A 3IU7A 3IG4A 1R5GA 4U6CA 4ZNGA 3MR1A 3Q6DA 1XGSA
chains in the Genus database with same CATH superfamily
4Z7MA 4U1BA 5D6FA 2P98A 5CDLA 2GG7A 3PKBA 4R60A 2BWYA 2V3ZA 3BIPA 3FM3A 1CHMA 2BH3A 4RZZA 2BWTA 5JI6A 3IL0A 4S01A 1B59A 2NQ7A 3IU9A 4PNCA 2EA4A 4U69A 2HOWA 3D27A 1YVMA 4IDYA 1WBQA 1WKMA 4FO7A 4IKTA 4FLJA 3CB6A 5FCHA 4QR8A 1BN5A 1YW9A 3TAVA 2ADUA 2MATA 3BIQA 5D6EA 4FO8A 4OOKA 2GG2A 3PEBA 3RVAA 3IU8A 4RGZ1 3PKDA 2GU7A 2BWXA 1C27A 1R58A 4U76A 4A6VA 1YW8A 3PKCA 3O5VA 3OOOA 2DFIA 4U6WA 1QXWA 2GG0A 2B3KA 1WL6A 5CLSA 4S00A 5CIKA 3RORA 2BHDA 1R5HA 4FLLA 4U6JA 1XGOA 1WY2A 2GU4A 2EVCA 2EVMA 2Q92A 2GG5A 3L24A 4ZWOA 5CDVA 2ZSGA 2BWSA 4ZWUA 4EGEA 1WLRA 1XNZA 1BOAA 2OAZA 2G6PA 1N51A 4FLKA 4FUKA 5E2CA 2BHBA 5CDEA 1KQ9A 4MATA 2BWWA 2GU6A 4ZWPA 3S6BA 3MX6A 2B3LA 4JUQA 2NQ6A 2P99A 4A6WA 1MATA 1QZYA 4IECA 2GG3A 3QOCA 2Q96A 1O0XA 5CE6A 1C22A 2P9AA 2Q94A 2GU5A 1WN1A 5CNXA 1KQ0A 3PKEA 2BHCA 2BB7A 2BWUA 2GA2A 4RZYA 4U71A 1M35A 4FKCA 2EA2A 1Y1NA 2GGCA 1C24A 1PV9A 3BITA 1WL9A 2IW2A 2GTXA 3FMRA 4U6EA 1YW7A 4HXXA 4KM3A 2V3YA 4IKRA 2BN7A 3CB5A 4S2TP 4IU6A 1W2MA 4PV4A 2GG8A 1B6AA 4S2RP 5FCFA 4IKSA 3CTZA 2Q93A 3MATA 3TB5A 3L7GA 2B3HA 2GG9A 4IPAA 1C23A 2BWVA 1XGNA 3PKAA 4U70A 1W7VA 1QXYA 5E5BA 2EVOA 2GZ5A 4IKUA 2OKNA 2Q95A 3OVKA 4FLIA 4B28A 4U75A 3FMQA 1C21A 5JFRA 4IF7A 2V3XA 4U6ZA 1JAWA 4U73A 1QXZA 2BHAA 3I7MA 5JHUA 2GGBA 1A16A 1XGMA 2Q8KA 1KP0A 1YJ3A 2V6CA 3PN9A 3IU7A 3IG4A 1R5GA 4U6CA 4ZNGA 3MR1A 3Q6DA 1XGSA
chains in the Genus database with same CATH topology
4Z7MA 4U1BA 5D6FA 2P98A 5CDLA 2GG7A 3PKBA 4R60A 2BWYA 2V3ZA 3BIPA 3FM3A 1CHMA 2BH3A 4RZZA 2BWTA 5JI6A 3IL0A 4S01A 1B59A 2NQ7A 3IU9A 4PNCA 2EA4A 4U69A 2HOWA 3D27A 1YVMA 4IDYA 1WBQA 1WKMA 4FO7A 4IKTA 4FLJA 3CB6A 5FCHA 4QR8A 1BN5A 1YW9A 3TAVA 2ADUA 2MATA 3BIQA 5D6EA 4FO8A 4OOKA 2GG2A 3PEBA 3RVAA 3IU8A 4RGZ1 3PKDA 2GU7A 2BWXA 1C27A 1R58A 4U76A 4A6VA 1YW8A 3PKCA 3O5VA 3OOOA 2DFIA 4U6WA 1QXWA 2GG0A 2B3KA 1WL6A 5CLSA 4S00A 5CIKA 3RORA 2BHDA 1R5HA 4FLLA 4U6JA 1XGOA 1WY2A 2GU4A 2EVCA 2EVMA 2Q92A 2GG5A 3L24A 4ZWOA 5CDVA 2ZSGA 2BWSA 4ZWUA 4EGEA 1WLRA 1XNZA 1BOAA 2OAZA 2G6PA 1N51A 4FLKA 4FUKA 5E2CA 2BHBA 5CDEA 1KQ9A 4MATA 2BWWA 2GU6A 4ZWPA 3S6BA 3MX6A 2B3LA 4JUQA 2NQ6A 2P99A 4A6WA 1MATA 1QZYA 4IECA 2GG3A 3QOCA 2Q96A 1O0XA 5CE6A 1C22A 2P9AA 2Q94A 2GU5A 1WN1A 5CNXA 1KQ0A 3PKEA 2BHCA 2BB7A 2BWUA 2GA2A 4RZYA 4U71A 1M35A 4FKCA 2EA2A 1Y1NA 2GGCA 1C24A 1PV9A 3BITA 1WL9A 2IW2A 2GTXA 3FMRA 4U6EA 1YW7A 4HXXA 4KM3A 2V3YA 4IKRA 2BN7A 3CB5A 4S2TP 4IU6A 1W2MA 4PV4A 2GG8A 1B6AA 4S2RP 5FCFA 4IKSA 3CTZA 2Q93A 3MATA 3TB5A 3L7GA 2B3HA 2GG9A 4IPAA 1C23A 2BWVA 1XGNA 3PKAA 4U70A 1W7VA 1QXYA 5E5BA 2EVOA 2GZ5A 4IKUA 2OKNA 2Q95A 3OVKA 4FLIA 4B28A 4U75A 3FMQA 1C21A 5JFRA 4IF7A 2V3XA 4U6ZA 1JAWA 4U73A 1QXZA 2BHAA 3I7MA 5JHUA 2GGBA 1A16A 1XGMA 2Q8KA 1KP0A 1YJ3A 2V6CA 3PN9A 3IU7A 3IG4A 1R5GA 4U6CA 4ZNGA 3MR1A 3Q6DA 1XGSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z7M A;  4U1B A;  5D6F A;  2P98 A;  5CDL A;  2GG7 A;  3PKB A;  4R60 A;  2BWY A;  2V3Z A;  3BIP A;  3FM3 A;  1CHM A;  2BH3 A;  4RZZ A;  2BWT A;  5JI6 A;  3IL0 A;  4S01 A;  1B59 A;  2NQ7 A;  3IU9 A;  4PNC A;  2EA4 A;  4U69 A;  2HOW A;  3D27 A;  1YVM A;  4IDY A;  1WBQ A;  1WKM A;  4FO7 A;  4IKT A;  4FLJ A;  3CB6 A;  5FCH A;  4QR8 A;  1BN5 A;  1YW9 A;  3TAV A;  2ADU A;  2MAT A;  3BIQ A;  5D6E A;  4FO8 A;  4OOK A;  2GG2 A;  3PEB A;  3RVA A;  3IU8 A;  4RGZ 1;  3PKD A;  2GU7 A;  2BWX A;  1C27 A;  1R58 A;  4U76 A;  4A6V A;  1YW8 A;  3PKC A;  3O5V A;  3OOO A;  2DFI A;  4U6W A;  1QXW A;  2GG0 A;  2B3K A;  1WL6 A;  5CLS A;  4S00 A;  5CIK A;  3ROR A;  2BHD A;  1R5H A;  4FLL A;  4U6J A;  1XGO A;  1WY2 A;  2GU4 A;  2EVC A;  2EVM A;  2Q92 A;  2GG5 A;  3L24 A;  4ZWO A;  5CDV A;  2ZSG A;  2BWS A;  4ZWU A;  4EGE A;  1WLR A;  1XNZ A;  1BOA A;  2OAZ A;  2G6P A;  1N51 A;  4FLK A;  4FUK A;  5E2C A;  2BHB A;  5CDE A;  1KQ9 A;  4MAT A;  2BWW A;  2GU6 A;  4ZWP A;  3S6B A;  3MX6 A;  2B3L A;  4JUQ A;  2NQ6 A;  2P99 A;  4A6W A;  1MAT A;  1QZY A;  4IEC A;  2GG3 A;  3QOC A;  2Q96 A;  1O0X A;  5CE6 A;  1C22 A;  2P9A A;  2Q94 A;  2GU5 A;  1WN1 A;  5CNX A;  1KQ0 A;  3PKE A;  2BHC A;  2BB7 A;  2BWU A;  2GA2 A;  4RZY A;  4U71 A;  1M35 A;  4FKC A;  2EA2 A;  1Y1N A;  2GGC A;  1C24 A;  1PV9 A;  3BIT A;  1WL9 A;  2IW2 A;  2GTX A;  3FMR A;  4U6E A;  1YW7 A;  4HXX A;  4KM3 A;  2V3Y A;  4IKR A;  2BN7 A;  3CB5 A;  4S2T P;  4IU6 A;  1W2M A;  4PV4 A;  2GG8 A;  1B6A A;  4S2R P;  5FCF A;  4IKS A;  3CTZ A;  2Q93 A;  3MAT A;  3TB5 A;  3L7G A;  2B3H A;  2GG9 A;  4IPA A;  1C23 A;  2BWV A;  1XGN A;  3PKA A;  4U70 A;  1W7V A;  1QXY A;  5E5B A;  2EVO A;  2GZ5 A;  4IKU A;  2OKN A;  2Q95 A;  3OVK A;  4FLI A;  4B28 A;  4U75 A;  3FMQ A;  1C21 A;  5JFR A;  4IF7 A;  2V3X A;  4U6Z A;  1JAW A;  4U73 A;  1QXZ A;  2BHA A;  3I7M A;  5JHU A;  2GGB A;  1A16 A;  1XGM A;  2Q8K A;  1KP0 A;  1YJ3 A;  2V6C A;  3PN9 A;  3IU7 A;  3IG4 A;  1R5G A;  4U6C A;  4ZNG A;  3MR1 A;  3Q6D A;  1XGS A; 
#chains in the Genus database with same CATH topology
 4Z7M A;  4U1B A;  5D6F A;  2P98 A;  5CDL A;  2GG7 A;  3PKB A;  4R60 A;  2BWY A;  2V3Z A;  3BIP A;  3FM3 A;  1CHM A;  2BH3 A;  4RZZ A;  2BWT A;  5JI6 A;  3IL0 A;  4S01 A;  1B59 A;  2NQ7 A;  3IU9 A;  4PNC A;  2EA4 A;  4U69 A;  2HOW A;  3D27 A;  1YVM A;  4IDY A;  1WBQ A;  1WKM A;  4FO7 A;  4IKT A;  4FLJ A;  3CB6 A;  5FCH A;  4QR8 A;  1BN5 A;  1YW9 A;  3TAV A;  2ADU A;  2MAT A;  3BIQ A;  5D6E A;  4FO8 A;  4OOK A;  2GG2 A;  3PEB A;  3RVA A;  3IU8 A;  4RGZ 1;  3PKD A;  2GU7 A;  2BWX A;  1C27 A;  1R58 A;  4U76 A;  4A6V A;  1YW8 A;  3PKC A;  3O5V A;  3OOO A;  2DFI A;  4U6W A;  1QXW A;  2GG0 A;  2B3K A;  1WL6 A;  5CLS A;  4S00 A;  5CIK A;  3ROR A;  2BHD A;  1R5H A;  4FLL A;  4U6J A;  1XGO A;  1WY2 A;  2GU4 A;  2EVC A;  2EVM A;  2Q92 A;  2GG5 A;  3L24 A;  4ZWO A;  5CDV A;  2ZSG A;  2BWS A;  4ZWU A;  4EGE A;  1WLR A;  1XNZ A;  1BOA A;  2OAZ A;  2G6P A;  1N51 A;  4FLK A;  4FUK A;  5E2C A;  2BHB A;  5CDE A;  1KQ9 A;  4MAT A;  2BWW A;  2GU6 A;  4ZWP A;  3S6B A;  3MX6 A;  2B3L A;  4JUQ A;  2NQ6 A;  2P99 A;  4A6W A;  1MAT A;  1QZY A;  4IEC A;  2GG3 A;  3QOC A;  2Q96 A;  1O0X A;  5CE6 A;  1C22 A;  2P9A A;  2Q94 A;  2GU5 A;  1WN1 A;  5CNX A;  1KQ0 A;  3PKE A;  2BHC A;  2BB7 A;  2BWU A;  2GA2 A;  4RZY A;  4U71 A;  1M35 A;  4FKC A;  2EA2 A;  1Y1N A;  2GGC A;  1C24 A;  1PV9 A;  3BIT A;  1WL9 A;  2IW2 A;  2GTX A;  3FMR A;  4U6E A;  1YW7 A;  4HXX A;  4KM3 A;  2V3Y A;  4IKR A;  2BN7 A;  3CB5 A;  4S2T P;  4IU6 A;  1W2M A;  4PV4 A;  2GG8 A;  1B6A A;  4S2R P;  5FCF A;  4IKS A;  3CTZ A;  2Q93 A;  3MAT A;  3TB5 A;  3L7G A;  2B3H A;  2GG9 A;  4IPA A;  1C23 A;  2BWV A;  1XGN A;  3PKA A;  4U70 A;  1W7V A;  1QXY A;  5E5B A;  2EVO A;  2GZ5 A;  4IKU A;  2OKN A;  2Q95 A;  3OVK A;  4FLI A;  4B28 A;  4U75 A;  3FMQ A;  1C21 A;  5JFR A;  4IF7 A;  2V3X A;  4U6Z A;  1JAW A;  4U73 A;  1QXZ A;  2BHA A;  3I7M A;  5JHU A;  2GGB A;  1A16 A;  1XGM A;  2Q8K A;  1KP0 A;  1YJ3 A;  2V6C A;  3PN9 A;  3IU7 A;  3IG4 A;  1R5G A;  4U6C A;  4ZNG A;  3MR1 A;  3Q6D A;  1XGS A; 
#chains in the Genus database with same CATH homology
 4Z7M A;  4U1B A;  5D6F A;  2P98 A;  5CDL A;  2GG7 A;  3PKB A;  4R60 A;  2BWY A;  2V3Z A;  3BIP A;  3FM3 A;  1CHM A;  2BH3 A;  4RZZ A;  2BWT A;  5JI6 A;  3IL0 A;  4S01 A;  1B59 A;  2NQ7 A;  3IU9 A;  4PNC A;  2EA4 A;  4U69 A;  2HOW A;  3D27 A;  1YVM A;  4IDY A;  1WBQ A;  1WKM A;  4FO7 A;  4IKT A;  4FLJ A;  3CB6 A;  5FCH A;  4QR8 A;  1BN5 A;  1YW9 A;  3TAV A;  2ADU A;  2MAT A;  3BIQ A;  5D6E A;  4FO8 A;  4OOK A;  2GG2 A;  3PEB A;  3RVA A;  3IU8 A;  4RGZ 1;  3PKD A;  2GU7 A;  2BWX A;  1C27 A;  1R58 A;  4U76 A;  4A6V A;  1YW8 A;  3PKC A;  3O5V A;  3OOO A;  2DFI A;  4U6W A;  1QXW A;  2GG0 A;  2B3K A;  1WL6 A;  5CLS A;  4S00 A;  5CIK A;  3ROR A;  2BHD A;  1R5H A;  4FLL A;  4U6J A;  1XGO A;  1WY2 A;  2GU4 A;  2EVC A;  2EVM A;  2Q92 A;  2GG5 A;  3L24 A;  4ZWO A;  5CDV A;  2ZSG A;  2BWS A;  4ZWU A;  4EGE A;  1WLR A;  1XNZ A;  1BOA A;  2OAZ A;  2G6P A;  1N51 A;  4FLK A;  4FUK A;  5E2C A;  2BHB A;  5CDE A;  1KQ9 A;  4MAT A;  2BWW A;  2GU6 A;  4ZWP A;  3S6B A;  3MX6 A;  2B3L A;  4JUQ A;  2NQ6 A;  2P99 A;  4A6W A;  1MAT A;  1QZY A;  4IEC A;  2GG3 A;  3QOC A;  2Q96 A;  1O0X A;  5CE6 A;  1C22 A;  2P9A A;  2Q94 A;  2GU5 A;  1WN1 A;  5CNX A;  1KQ0 A;  3PKE A;  2BHC A;  2BB7 A;  2BWU A;  2GA2 A;  4RZY A;  4U71 A;  1M35 A;  4FKC A;  2EA2 A;  1Y1N A;  2GGC A;  1C24 A;  1PV9 A;  3BIT A;  1WL9 A;  2IW2 A;  2GTX A;  3FMR A;  4U6E A;  1YW7 A;  4HXX A;  4KM3 A;  2V3Y A;  4IKR A;  2BN7 A;  3CB5 A;  4S2T P;  4IU6 A;  1W2M A;  4PV4 A;  2GG8 A;  1B6A A;  4S2R P;  5FCF A;  4IKS A;  3CTZ A;  2Q93 A;  3MAT A;  3TB5 A;  3L7G A;  2B3H A;  2GG9 A;  4IPA A;  1C23 A;  2BWV A;  1XGN A;  3PKA A;  4U70 A;  1W7V A;  1QXY A;  5E5B A;  2EVO A;  2GZ5 A;  4IKU A;  2OKN A;  2Q95 A;  3OVK A;  4FLI A;  4B28 A;  4U75 A;  3FMQ A;  1C21 A;  5JFR A;  4IF7 A;  2V3X A;  4U6Z A;  1JAW A;  4U73 A;  1QXZ A;  2BHA A;  3I7M A;  5JHU A;  2GGB A;  1A16 A;  1XGM A;  2Q8K A;  1KP0 A;  1YJ3 A;  2V6C A;  3PN9 A;  3IU7 A;  3IG4 A;  1R5G A;  4U6C A;  4ZNG A;  3MR1 A;  3Q6D A;  1XGS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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