1PV9A

Prolidase from pyrococcus furiosus
Total Genus 112
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
112
sequence length
338
structure length
337
Chain Sequence
LVKFMDENSIDRVFIAKPVNVYYFSGTSPLGGGYIIVDGDEATLYVPELEYEMAKEESKLPVVKFKKFDEIYEILKNTETLGIEGTLSYSMVENFKEKSVKEFKKIDDVIKDLRIIKTKEEIEIIEKACEIADKAVMAAIEEITEGKREREVAAKVEYLMKMNGAEKPAFDTIIASGHRSALPHGVASDKRIERGDLVVIDLGALYNHYNSDITRTIVVGSPNEKQREIYEIVLEAQKRAVEAAKPGMTAKELDSIAREIIKEYGYGDYFIHSLGHGVGLEIHEWPRISQYDETVLKEGMVITIEPGIYIPKLGGVRIEDTVLITENGAKRLTKTER
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
publication title Structure of the Prolidase from Pyrococcus furiosus.
pubmed doi rcsb
source organism Pyrococcus furiosus
molecule tags Hydrolase
total genus 112
structure length 337
sequence length 338
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2003-06-27

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1pv9A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1pv9A02
2V3XA 3PN9A 1XGNA 3IG4A 5JI6A 2BWSA 5CNXA 1XGMA 3L7GA 2GU5A 1WL6A 1Y1NA 2P98A 1WN1A 2GG2A 2HOWA 4IKRA 2GG0A 2Q96A 1KQ9A 1R5GA 2EVOA 2GG8A 3FMRA 3Q6DA 2BH3A 3PKDA 1WL9A 1QXZA 4FKCA 2NQ7A 4S2RP 1KQ0A 2ADUA 3PKCA 1QZYA 3TAVA 4ZNGA 5CDEA 1C24A 4U6ZA 3PKAA 2B3LA 1JAWA 3O5VA 3IU7A 5CDLA 3BIPA 3RVAA 4IF7A 2EVMA 5CLSA 1QXWA 3BITA 4IECA 1WKMA 1CHMA 1YW8A 2DFIA 4A6WA 4HXXA 4OOKA 4S00A 5CDVA 1C21A 3PKEA 1B6AA 5D6FA 2V6CA 2B3HA 5JFRA 4R60A 1BN5A 1YW9A 4U6WA 2BHAA 4Z7MA 4U75A 2P9AA 2V3YA 2BHBA 4U6CA 4IPAA 3TB5A 2B3KA 2GTXA 1KP0A 5CIKA 4FLJA 4IDYA 1PV9A 2OKNA 2BN7A 2GG9A 4U69A 4U76A 3IU8A 2Q95A 4RZYA 2OAZA 2GGBA 3MATA 3FMQA 4U6JA 5E5BA 5CE6A 1C23A 2MATA 2GG7A 4JUQA 1XNZA 4S2TP 2EA2A 1A16A 5D6EA 4PV4A 2BWTA 1R58A 4FO7A 2Q93A 2GU6A 4S01A 2ZSGA 5E2CA 4U73A 1O0XA 4PNCA 1WBQA 2BWWA 1YJ3A 3S6BA 3RORA 2BHDA 4ZWPA 3FM3A 3IU9A 3OOOA 1B59A 2Q8KA 2NQ6A 1WY2A 4ZWUA 4IU6A 1YVMA 4U71A 4KM3A 3MX6A 4A6VA 4RGZ1 1QXYA 3I7MA 1YW7A 1C22A 4U1BA 2V3ZA 1XGSA 4FUKA 1WLRA 3PKBA 2GG5A 4ZWOA 2GG3A 2EA4A 2EVCA 2BHCA 1W2MA 4MATA 1M35A 2GU7A 3CB5A 1C27A 2BWVA 2GA2A 3MR1A 4IKUA 4U6EA 2P99A 4U70A 2G6PA 2BWXA 1R5HA 4FO8A 1N51A 3OVKA 4B28A 4IKSA 5FCFA 2BB7A 3QOCA 3IL0A 4EGEA 1MATA 3D27A 4FLKA 5FCHA 4FLIA 2Q94A 4QR8A 3BIQA 2GGCA 1W7VA 2Q92A 3CTZA 3PEBA 2GZ5A 3L24A 2GU4A 2BWYA 4RZZA 1BOAA 4IKTA 4FLLA 3CB6A 2BWUA 2IW2A 1XGOA 5JHUA
chains in the Genus database with same CATH superfamily
2V3XA 3PN9A 1XGNA 3IG4A 5JI6A 2BWSA 5CNXA 1XGMA 3L7GA 2GU5A 1WL6A 1Y1NA 2P98A 1WN1A 2GG2A 2HOWA 4IKRA 2GG0A 2Q96A 1KQ9A 1R5GA 2EVOA 2GG8A 3FMRA 3Q6DA 2BH3A 3PKDA 1WL9A 1QXZA 4FKCA 2NQ7A 4S2RP 1KQ0A 2ADUA 3PKCA 1QZYA 3TAVA 4ZNGA 5CDEA 1C24A 4U6ZA 3PKAA 2B3LA 1JAWA 3O5VA 3IU7A 5CDLA 3BIPA 3RVAA 4IF7A 2EVMA 5CLSA 1QXWA 3BITA 4IECA 1WKMA 1CHMA 1YW8A 2DFIA 4A6WA 4HXXA 4OOKA 4S00A 5CDVA 1C21A 3PKEA 1B6AA 5D6FA 2V6CA 2B3HA 5JFRA 4R60A 1BN5A 1YW9A 4U6WA 2BHAA 4Z7MA 4U75A 2P9AA 2V3YA 2BHBA 4U6CA 4IPAA 3TB5A 2B3KA 2GTXA 1KP0A 5CIKA 4FLJA 4IDYA 1PV9A 2OKNA 2BN7A 2GG9A 4U69A 4U76A 3IU8A 2Q95A 4RZYA 2OAZA 2GGBA 3MATA 3FMQA 4U6JA 5E5BA 5CE6A 1C23A 2MATA 2GG7A 4JUQA 1XNZA 4S2TP 2EA2A 1A16A 5D6EA 4PV4A 2BWTA 1R58A 4FO7A 2Q93A 2GU6A 4S01A 2ZSGA 5E2CA 4U73A 1O0XA 4PNCA 1WBQA 2BWWA 1YJ3A 3S6BA 3RORA 2BHDA 4ZWPA 3FM3A 3IU9A 3OOOA 1B59A 2Q8KA 2NQ6A 1WY2A 4ZWUA 4IU6A 1YVMA 4U71A 4KM3A 3MX6A 4A6VA 4RGZ1 1QXYA 3I7MA 1YW7A 1C22A 4U1BA 2V3ZA 1XGSA 4FUKA 1WLRA 3PKBA 2GG5A 4ZWOA 2GG3A 2EA4A 2EVCA 2BHCA 1W2MA 4MATA 1M35A 2GU7A 3CB5A 1C27A 2BWVA 2GA2A 3MR1A 4IKUA 4U6EA 2P99A 4U70A 2G6PA 2BWXA 1R5HA 4FO8A 1N51A 3OVKA 4B28A 4IKSA 5FCFA 2BB7A 3QOCA 3IL0A 4EGEA 1MATA 3D27A 4FLKA 5FCHA 4FLIA 2Q94A 4QR8A 3BIQA 2GGCA 1W7VA 2Q92A 3CTZA 3PEBA 2GZ5A 3L24A 2GU4A 2BWYA 4RZZA 1BOAA 4IKTA 4FLLA 3CB6A 2BWUA 2IW2A 1XGOA 5JHUA
chains in the Genus database with same CATH topology
2V3XA 3PN9A 1XGNA 3IG4A 5JI6A 2BWSA 5CNXA 1XGMA 3L7GA 2GU5A 1WL6A 1Y1NA 2P98A 1WN1A 2GG2A 2HOWA 4IKRA 2GG0A 2Q96A 1KQ9A 1R5GA 2EVOA 2GG8A 3FMRA 3Q6DA 2BH3A 3PKDA 1WL9A 1QXZA 4FKCA 2NQ7A 4S2RP 1KQ0A 2ADUA 3PKCA 1QZYA 3TAVA 4ZNGA 5CDEA 1C24A 4U6ZA 3PKAA 2B3LA 1JAWA 3O5VA 3IU7A 5CDLA 3BIPA 3RVAA 4IF7A 2EVMA 5CLSA 1QXWA 3BITA 4IECA 1WKMA 1CHMA 1YW8A 2DFIA 4A6WA 4HXXA 4OOKA 4S00A 5CDVA 1C21A 3PKEA 1B6AA 5D6FA 2V6CA 2B3HA 5JFRA 4R60A 1BN5A 1YW9A 4U6WA 2BHAA 4Z7MA 4U75A 2P9AA 2V3YA 2BHBA 4U6CA 4IPAA 3TB5A 2B3KA 2GTXA 1KP0A 5CIKA 4FLJA 4IDYA 1PV9A 2OKNA 2BN7A 2GG9A 4U69A 4U76A 3IU8A 2Q95A 4RZYA 2OAZA 2GGBA 3MATA 3FMQA 4U6JA 5E5BA 5CE6A 1C23A 2MATA 2GG7A 4JUQA 1XNZA 4S2TP 2EA2A 1A16A 5D6EA 4PV4A 2BWTA 1R58A 4FO7A 2Q93A 2GU6A 4S01A 2ZSGA 5E2CA 4U73A 1O0XA 4PNCA 1WBQA 2BWWA 1YJ3A 3S6BA 3RORA 2BHDA 4ZWPA 3FM3A 3IU9A 3OOOA 1B59A 2Q8KA 2NQ6A 1WY2A 4ZWUA 4IU6A 1YVMA 4U71A 4KM3A 3MX6A 4A6VA 4RGZ1 1QXYA 3I7MA 1YW7A 1C22A 4U1BA 2V3ZA 1XGSA 4FUKA 1WLRA 3PKBA 2GG5A 4ZWOA 2GG3A 2EA4A 2EVCA 2BHCA 1W2MA 4MATA 1M35A 2GU7A 3CB5A 1C27A 2BWVA 2GA2A 3MR1A 4IKUA 4U6EA 2P99A 4U70A 2G6PA 2BWXA 1R5HA 4FO8A 1N51A 3OVKA 4B28A 4IKSA 5FCFA 2BB7A 3QOCA 3IL0A 4EGEA 1MATA 3D27A 4FLKA 5FCHA 4FLIA 2Q94A 4QR8A 3BIQA 2GGCA 1W7VA 2Q92A 3CTZA 3PEBA 2GZ5A 3L24A 2GU4A 2BWYA 4RZZA 1BOAA 4IKTA 4FLLA 3CB6A 2BWUA 2IW2A 1XGOA 5JHUA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2V3X A;  3PN9 A;  1XGN A;  3IG4 A;  5JI6 A;  2BWS A;  5CNX A;  1XGM A;  3L7G A;  2GU5 A;  1WL6 A;  1Y1N A;  2P98 A;  1WN1 A;  2GG2 A;  2HOW A;  4IKR A;  2GG0 A;  2Q96 A;  1KQ9 A;  1R5G A;  2EVO A;  2GG8 A;  3FMR A;  3Q6D A;  2BH3 A;  3PKD A;  1WL9 A;  1QXZ A;  4FKC A;  2NQ7 A;  4S2R P;  1KQ0 A;  2ADU A;  3PKC A;  1QZY A;  3TAV A;  4ZNG A;  5CDE A;  1C24 A;  4U6Z A;  3PKA A;  2B3L A;  1JAW A;  3O5V A;  3IU7 A;  5CDL A;  3BIP A;  3RVA A;  4IF7 A;  2EVM A;  5CLS A;  1QXW A;  3BIT A;  4IEC A;  1WKM A;  1CHM A;  1YW8 A;  2DFI A;  4A6W A;  4HXX A;  4OOK A;  4S00 A;  5CDV A;  1C21 A;  3PKE A;  1B6A A;  5D6F A;  2V6C A;  2B3H A;  5JFR A;  4R60 A;  1BN5 A;  1YW9 A;  4U6W A;  2BHA A;  4Z7M A;  4U75 A;  2P9A A;  2V3Y A;  2BHB A;  4U6C A;  4IPA A;  3TB5 A;  2B3K A;  2GTX A;  1KP0 A;  5CIK A;  4FLJ A;  4IDY A;  1PV9 A;  2OKN A;  2BN7 A;  2GG9 A;  4U69 A;  4U76 A;  3IU8 A;  2Q95 A;  4RZY A;  2OAZ A;  2GGB A;  3MAT A;  3FMQ A;  4U6J A;  5E5B A;  5CE6 A;  1C23 A;  2MAT A;  2GG7 A;  4JUQ A;  1XNZ A;  4S2T P;  2EA2 A;  1A16 A;  5D6E A;  4PV4 A;  2BWT A;  1R58 A;  4FO7 A;  2Q93 A;  2GU6 A;  4S01 A;  2ZSG A;  5E2C A;  4U73 A;  1O0X A;  4PNC A;  1WBQ A;  2BWW A;  1YJ3 A;  3S6B A;  3ROR A;  2BHD A;  4ZWP A;  3FM3 A;  3IU9 A;  3OOO A;  1B59 A;  2Q8K A;  2NQ6 A;  1WY2 A;  4ZWU A;  4IU6 A;  1YVM A;  4U71 A;  4KM3 A;  3MX6 A;  4A6V A;  4RGZ 1;  1QXY A;  3I7M A;  1YW7 A;  1C22 A;  4U1B A;  2V3Z A;  1XGS A;  4FUK A;  1WLR A;  3PKB A;  2GG5 A;  4ZWO A;  2GG3 A;  2EA4 A;  2EVC A;  2BHC A;  1W2M A;  4MAT A;  1M35 A;  2GU7 A;  3CB5 A;  1C27 A;  2BWV A;  2GA2 A;  3MR1 A;  4IKU A;  4U6E A;  2P99 A;  4U70 A;  2G6P A;  2BWX A;  1R5H A;  4FO8 A;  1N51 A;  3OVK A;  4B28 A;  4IKS A;  5FCF A;  2BB7 A;  3QOC A;  3IL0 A;  4EGE A;  1MAT A;  3D27 A;  4FLK A;  5FCH A;  4FLI A;  2Q94 A;  4QR8 A;  3BIQ A;  2GGC A;  1W7V A;  2Q92 A;  3CTZ A;  3PEB A;  2GZ5 A;  3L24 A;  2GU4 A;  2BWY A;  4RZZ A;  1BOA A;  4IKT A;  4FLL A;  3CB6 A;  2BWU A;  2IW2 A;  1XGO A;  5JHU A; 
#chains in the Genus database with same CATH topology
 2V3X A;  3PN9 A;  1XGN A;  3IG4 A;  5JI6 A;  2BWS A;  5CNX A;  1XGM A;  3L7G A;  2GU5 A;  1WL6 A;  1Y1N A;  2P98 A;  1WN1 A;  2GG2 A;  2HOW A;  4IKR A;  2GG0 A;  2Q96 A;  1KQ9 A;  1R5G A;  2EVO A;  2GG8 A;  3FMR A;  3Q6D A;  2BH3 A;  3PKD A;  1WL9 A;  1QXZ A;  4FKC A;  2NQ7 A;  4S2R P;  1KQ0 A;  2ADU A;  3PKC A;  1QZY A;  3TAV A;  4ZNG A;  5CDE A;  1C24 A;  4U6Z A;  3PKA A;  2B3L A;  1JAW A;  3O5V A;  3IU7 A;  5CDL A;  3BIP A;  3RVA A;  4IF7 A;  2EVM A;  5CLS A;  1QXW A;  3BIT A;  4IEC A;  1WKM A;  1CHM A;  1YW8 A;  2DFI A;  4A6W A;  4HXX A;  4OOK A;  4S00 A;  5CDV A;  1C21 A;  3PKE A;  1B6A A;  5D6F A;  2V6C A;  2B3H A;  5JFR A;  4R60 A;  1BN5 A;  1YW9 A;  4U6W A;  2BHA A;  4Z7M A;  4U75 A;  2P9A A;  2V3Y A;  2BHB A;  4U6C A;  4IPA A;  3TB5 A;  2B3K A;  2GTX A;  1KP0 A;  5CIK A;  4FLJ A;  4IDY A;  1PV9 A;  2OKN A;  2BN7 A;  2GG9 A;  4U69 A;  4U76 A;  3IU8 A;  2Q95 A;  4RZY A;  2OAZ A;  2GGB A;  3MAT A;  3FMQ A;  4U6J A;  5E5B A;  5CE6 A;  1C23 A;  2MAT A;  2GG7 A;  4JUQ A;  1XNZ A;  4S2T P;  2EA2 A;  1A16 A;  5D6E A;  4PV4 A;  2BWT A;  1R58 A;  4FO7 A;  2Q93 A;  2GU6 A;  4S01 A;  2ZSG A;  5E2C A;  4U73 A;  1O0X A;  4PNC A;  1WBQ A;  2BWW A;  1YJ3 A;  3S6B A;  3ROR A;  2BHD A;  4ZWP A;  3FM3 A;  3IU9 A;  3OOO A;  1B59 A;  2Q8K A;  2NQ6 A;  1WY2 A;  4ZWU A;  4IU6 A;  1YVM A;  4U71 A;  4KM3 A;  3MX6 A;  4A6V A;  4RGZ 1;  1QXY A;  3I7M A;  1YW7 A;  1C22 A;  4U1B A;  2V3Z A;  1XGS A;  4FUK A;  1WLR A;  3PKB A;  2GG5 A;  4ZWO A;  2GG3 A;  2EA4 A;  2EVC A;  2BHC A;  1W2M A;  4MAT A;  1M35 A;  2GU7 A;  3CB5 A;  1C27 A;  2BWV A;  2GA2 A;  3MR1 A;  4IKU A;  4U6E A;  2P99 A;  4U70 A;  2G6P A;  2BWX A;  1R5H A;  4FO8 A;  1N51 A;  3OVK A;  4B28 A;  4IKS A;  5FCF A;  2BB7 A;  3QOC A;  3IL0 A;  4EGE A;  1MAT A;  3D27 A;  4FLK A;  5FCH A;  4FLI A;  2Q94 A;  4QR8 A;  3BIQ A;  2GGC A;  1W7V A;  2Q92 A;  3CTZ A;  3PEB A;  2GZ5 A;  3L24 A;  2GU4 A;  2BWY A;  4RZZ A;  1BOA A;  4IKT A;  4FLL A;  3CB6 A;  2BWU A;  2IW2 A;  1XGO A;  5JHU A; 
#chains in the Genus database with same CATH homology
 2V3X A;  3PN9 A;  1XGN A;  3IG4 A;  5JI6 A;  2BWS A;  5CNX A;  1XGM A;  3L7G A;  2GU5 A;  1WL6 A;  1Y1N A;  2P98 A;  1WN1 A;  2GG2 A;  2HOW A;  4IKR A;  2GG0 A;  2Q96 A;  1KQ9 A;  1R5G A;  2EVO A;  2GG8 A;  3FMR A;  3Q6D A;  2BH3 A;  3PKD A;  1WL9 A;  1QXZ A;  4FKC A;  2NQ7 A;  4S2R P;  1KQ0 A;  2ADU A;  3PKC A;  1QZY A;  3TAV A;  4ZNG A;  5CDE A;  1C24 A;  4U6Z A;  3PKA A;  2B3L A;  1JAW A;  3O5V A;  3IU7 A;  5CDL A;  3BIP A;  3RVA A;  4IF7 A;  2EVM A;  5CLS A;  1QXW A;  3BIT A;  4IEC A;  1WKM A;  1CHM A;  1YW8 A;  2DFI A;  4A6W A;  4HXX A;  4OOK A;  4S00 A;  5CDV A;  1C21 A;  3PKE A;  1B6A A;  5D6F A;  2V6C A;  2B3H A;  5JFR A;  4R60 A;  1BN5 A;  1YW9 A;  4U6W A;  2BHA A;  4Z7M A;  4U75 A;  2P9A A;  2V3Y A;  2BHB A;  4U6C A;  4IPA A;  3TB5 A;  2B3K A;  2GTX A;  1KP0 A;  5CIK A;  4FLJ A;  4IDY A;  1PV9 A;  2OKN A;  2BN7 A;  2GG9 A;  4U69 A;  4U76 A;  3IU8 A;  2Q95 A;  4RZY A;  2OAZ A;  2GGB A;  3MAT A;  3FMQ A;  4U6J A;  5E5B A;  5CE6 A;  1C23 A;  2MAT A;  2GG7 A;  4JUQ A;  1XNZ A;  4S2T P;  2EA2 A;  1A16 A;  5D6E A;  4PV4 A;  2BWT A;  1R58 A;  4FO7 A;  2Q93 A;  2GU6 A;  4S01 A;  2ZSG A;  5E2C A;  4U73 A;  1O0X A;  4PNC A;  1WBQ A;  2BWW A;  1YJ3 A;  3S6B A;  3ROR A;  2BHD A;  4ZWP A;  3FM3 A;  3IU9 A;  3OOO A;  1B59 A;  2Q8K A;  2NQ6 A;  1WY2 A;  4ZWU A;  4IU6 A;  1YVM A;  4U71 A;  4KM3 A;  3MX6 A;  4A6V A;  4RGZ 1;  1QXY A;  3I7M A;  1YW7 A;  1C22 A;  4U1B A;  2V3Z A;  1XGS A;  4FUK A;  1WLR A;  3PKB A;  2GG5 A;  4ZWO A;  2GG3 A;  2EA4 A;  2EVC A;  2BHC A;  1W2M A;  4MAT A;  1M35 A;  2GU7 A;  3CB5 A;  1C27 A;  2BWV A;  2GA2 A;  3MR1 A;  4IKU A;  4U6E A;  2P99 A;  4U70 A;  2G6P A;  2BWX A;  1R5H A;  4FO8 A;  1N51 A;  3OVK A;  4B28 A;  4IKS A;  5FCF A;  2BB7 A;  3QOC A;  3IL0 A;  4EGE A;  1MAT A;  3D27 A;  4FLK A;  5FCH A;  4FLI A;  2Q94 A;  4QR8 A;  3BIQ A;  2GGC A;  1W7V A;  2Q92 A;  3CTZ A;  3PEB A;  2GZ5 A;  3L24 A;  2GU4 A;  2BWY A;  4RZZ A;  1BOA A;  4IKT A;  4FLL A;  3CB6 A;  2BWU A;  2IW2 A;  1XGO A;  5JHU A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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