2Q93A

E. coli methionine aminopeptidase mn-form with inhibitor b21
Total Genus 83
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
263
structure length
263
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Escherichia coli
total genus 83
structure length 263
sequence length 263
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2q93A00
1CHMA 3L24A 1B6AA 2EVOA 3PKDA 4FUKA 4ZWPA 2Q8KA 3PKBA 4Z7MA 4FLLA 5D6FA 3RORA 1QZYA 4OOKA 2EA2A 1R58A 2Q95A 5JHUA 2MATA 4IF7A 4FLKA 3IG4A 3TAVA 4ZNGA 2BHBA 1WLRA 4S2RP 2BWVA 4U71A 2P99A 4S2TP 3S6BA 4IKTA 1C27A 2Q94A 1C24A 2Q96A 1WL6A 2BHAA 1M35A 2GGCA 2B3LA 2BHCA 4IKSA 1QXYA 2ADUA 1YW8A 4S01A 2GA2A 1O0XA 4U69A 4U75A 4RZZA 5CNXA 2GG0A 1KQ9A 2V3YA 2V6CA 4U1BA 1XGMA 4U6WA 4MATA 2B3KA 1XGNA 3PKCA 5CDVA 3TB5A 1B59A 3BITA 2IW2A 4U6ZA 2GU4A 1R5HA 4PNCA 5JFRA 4FLIA 4HXXA 5CE6A 2BN7A 1KP0A 2OKNA 2BB7A 2Q92A 2V3ZA 2P98A 2Q93A 4U6JA 4IECA 1A16A 2GG5A 2P9AA 1BN5A 2GU5A 3CB6A 1N51A 4JUQA 1BOAA 4PV4A 1QXZA 1R5GA 3RVAA 3CB5A 2BWTA 4ZWOA 1QXWA 1YW9A 2BWUA 1XGOA 2BWSA 4B28A 1WN1A 3PKEA 4U76A 5FCHA 3MR1A 3CTZA 2OAZA 2NQ7A 1PV9A 2GG9A 3FMRA 2BWXA 5E5BA 1W2MA 3IU8A 5CDLA 2V3XA 2B3HA 2EVMA 4R60A 3BIPA 4IKUA 4IPAA 2GU7A 4U6EA 2BWYA 4A6VA 4S00A 2DFIA 1XGSA 1C23A 2BWWA 2GG2A 1W7VA 2EA4A 1C22A 1WY2A 1Y1NA 1JAWA 2GG7A 3FMQA 4FO7A 2GU6A 3IU9A 2GG8A 3PKAA 2NQ6A 5CLSA 4FLJA 2GG3A 5CIKA 4EGEA 1WL9A 2BH3A 1YW7A 1C21A 4FO8A 1YVMA 4QR8A 4U70A 1XNZA 3D27A 3L7GA 4IKRA 4IU6A 5JI6A 5D6EA 4RZYA 5CDEA 5FCFA 2HOWA 4U73A 2GGBA 2GTXA 1YJ3A 4ZWUA 3MX6A 4KM3A 2ZSGA 2EVCA 3BIQA 2G6PA 4RGZ1 4U6CA 1MATA 1KQ0A 1WBQA 1WKMA 2BHDA 3IU7A 3MATA 3Q6DA 4FKCA 4IDYA 2GZ5A 4A6WA 3FM3A
chains in the Genus database with same CATH superfamily
1CHMA 3L24A 1B6AA 2EVOA 3PKDA 4FUKA 4ZWPA 2Q8KA 3PKBA 4Z7MA 4FLLA 5D6FA 3RORA 1QZYA 4OOKA 2EA2A 1R58A 2Q95A 5JHUA 2MATA 4IF7A 4FLKA 3IG4A 3TAVA 4ZNGA 2BHBA 1WLRA 4S2RP 2BWVA 4U71A 2P99A 4S2TP 3S6BA 4IKTA 1C27A 2Q94A 1C24A 2Q96A 1WL6A 2BHAA 1M35A 2GGCA 2B3LA 2BHCA 4IKSA 1QXYA 2ADUA 1YW8A 4S01A 2GA2A 1O0XA 4U69A 4U75A 4RZZA 5CNXA 2GG0A 1KQ9A 2V3YA 2V6CA 4U1BA 1XGMA 4U6WA 4MATA 2B3KA 1XGNA 3PKCA 5CDVA 3TB5A 1B59A 3BITA 2IW2A 4U6ZA 2GU4A 1R5HA 4PNCA 5JFRA 4FLIA 4HXXA 5CE6A 2BN7A 1KP0A 2OKNA 2BB7A 2Q92A 2V3ZA 2P98A 2Q93A 4U6JA 4IECA 1A16A 2GG5A 2P9AA 1BN5A 2GU5A 3CB6A 1N51A 4JUQA 1BOAA 4PV4A 1QXZA 1R5GA 3RVAA 3CB5A 2BWTA 4ZWOA 1QXWA 1YW9A 2BWUA 1XGOA 2BWSA 4B28A 1WN1A 3PKEA 4U76A 5FCHA 3MR1A 3CTZA 2OAZA 2NQ7A 1PV9A 2GG9A 3FMRA 2BWXA 5E5BA 1W2MA 3IU8A 5CDLA 2V3XA 2B3HA 2EVMA 4R60A 3BIPA 4IKUA 4IPAA 2GU7A 4U6EA 2BWYA 4A6VA 4S00A 2DFIA 1XGSA 1C23A 2BWWA 2GG2A 1W7VA 2EA4A 1C22A 1WY2A 1Y1NA 1JAWA 2GG7A 3FMQA 4FO7A 2GU6A 3IU9A 2GG8A 3PKAA 2NQ6A 5CLSA 4FLJA 2GG3A 5CIKA 4EGEA 1WL9A 2BH3A 1YW7A 1C21A 4FO8A 1YVMA 4QR8A 4U70A 1XNZA 3D27A 3L7GA 4IKRA 4IU6A 5JI6A 5D6EA 4RZYA 5CDEA 5FCFA 2HOWA 4U73A 2GGBA 2GTXA 1YJ3A 4ZWUA 3MX6A 4KM3A 2ZSGA 2EVCA 3BIQA 2G6PA 4RGZ1 4U6CA 1MATA 1KQ0A 1WBQA 1WKMA 2BHDA 3IU7A 3MATA 3Q6DA 4FKCA 4IDYA 2GZ5A 4A6WA 3FM3A
chains in the Genus database with same CATH topology
1CHMA 3L24A 1B6AA 2EVOA 3PKDA 4FUKA 4ZWPA 2Q8KA 3PKBA 4Z7MA 4FLLA 5D6FA 3RORA 1QZYA 4OOKA 2EA2A 1R58A 2Q95A 5JHUA 2MATA 4IF7A 4FLKA 3IG4A 3TAVA 4ZNGA 2BHBA 1WLRA 4S2RP 2BWVA 4U71A 2P99A 4S2TP 3S6BA 4IKTA 1C27A 2Q94A 1C24A 2Q96A 1WL6A 2BHAA 1M35A 2GGCA 2B3LA 2BHCA 4IKSA 1QXYA 2ADUA 1YW8A 4S01A 2GA2A 1O0XA 4U69A 4U75A 4RZZA 5CNXA 2GG0A 1KQ9A 2V3YA 2V6CA 4U1BA 1XGMA 4U6WA 4MATA 2B3KA 1XGNA 3PKCA 5CDVA 3TB5A 1B59A 3BITA 2IW2A 4U6ZA 2GU4A 1R5HA 4PNCA 5JFRA 4FLIA 4HXXA 5CE6A 2BN7A 1KP0A 2OKNA 2BB7A 2Q92A 2V3ZA 2P98A 2Q93A 4U6JA 4IECA 1A16A 2GG5A 2P9AA 1BN5A 2GU5A 3CB6A 1N51A 4JUQA 1BOAA 4PV4A 1QXZA 1R5GA 3RVAA 3CB5A 2BWTA 4ZWOA 1QXWA 1YW9A 2BWUA 1XGOA 2BWSA 4B28A 1WN1A 3PKEA 4U76A 5FCHA 3MR1A 3CTZA 2OAZA 2NQ7A 1PV9A 2GG9A 3FMRA 2BWXA 5E5BA 1W2MA 3IU8A 5CDLA 2V3XA 2B3HA 2EVMA 4R60A 3BIPA 4IKUA 4IPAA 2GU7A 4U6EA 2BWYA 4A6VA 4S00A 2DFIA 1XGSA 1C23A 2BWWA 2GG2A 1W7VA 2EA4A 1C22A 1WY2A 1Y1NA 1JAWA 2GG7A 3FMQA 4FO7A 2GU6A 3IU9A 2GG8A 3PKAA 2NQ6A 5CLSA 4FLJA 2GG3A 5CIKA 4EGEA 1WL9A 2BH3A 1YW7A 1C21A 4FO8A 1YVMA 4QR8A 4U70A 1XNZA 3D27A 3L7GA 4IKRA 4IU6A 5JI6A 5D6EA 4RZYA 5CDEA 5FCFA 2HOWA 4U73A 2GGBA 2GTXA 1YJ3A 4ZWUA 3MX6A 4KM3A 2ZSGA 2EVCA 3BIQA 2G6PA 4RGZ1 4U6CA 1MATA 1KQ0A 1WBQA 1WKMA 2BHDA 3IU7A 3MATA 3Q6DA 4FKCA 4IDYA 2GZ5A 4A6WA 3FM3A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1CHM A;  3L24 A;  1B6A A;  2EVO A;  3PKD A;  4FUK A;  4ZWP A;  2Q8K A;  3PKB A;  4Z7M A;  4FLL A;  5D6F A;  3ROR A;  1QZY A;  4OOK A;  2EA2 A;  1R58 A;  2Q95 A;  5JHU A;  2MAT A;  4IF7 A;  4FLK A;  3IG4 A;  3TAV A;  4ZNG A;  2BHB A;  1WLR A;  4S2R P;  2BWV A;  4U71 A;  2P99 A;  4S2T P;  3S6B A;  4IKT A;  1C27 A;  2Q94 A;  1C24 A;  2Q96 A;  1WL6 A;  2BHA A;  1M35 A;  2GGC A;  2B3L A;  2BHC A;  4IKS A;  1QXY A;  2ADU A;  1YW8 A;  4S01 A;  2GA2 A;  1O0X A;  4U69 A;  4U75 A;  4RZZ A;  5CNX A;  2GG0 A;  1KQ9 A;  2V3Y A;  2V6C A;  4U1B A;  1XGM A;  4U6W A;  4MAT A;  2B3K A;  1XGN A;  3PKC A;  5CDV A;  3TB5 A;  1B59 A;  3BIT A;  2IW2 A;  4U6Z A;  2GU4 A;  1R5H A;  4PNC A;  5JFR A;  4FLI A;  4HXX A;  5CE6 A;  2BN7 A;  1KP0 A;  2OKN A;  2BB7 A;  2Q92 A;  2V3Z A;  2P98 A;  2Q93 A;  4U6J A;  4IEC A;  1A16 A;  2GG5 A;  2P9A A;  1BN5 A;  2GU5 A;  3CB6 A;  1N51 A;  4JUQ A;  1BOA A;  4PV4 A;  1QXZ A;  1R5G A;  3RVA A;  3CB5 A;  2BWT A;  4ZWO A;  1QXW A;  1YW9 A;  2BWU A;  1XGO A;  2BWS A;  4B28 A;  1WN1 A;  3PKE A;  4U76 A;  5FCH A;  3MR1 A;  3CTZ A;  2OAZ A;  2NQ7 A;  1PV9 A;  2GG9 A;  3FMR A;  2BWX A;  5E5B A;  1W2M A;  3IU8 A;  5CDL A;  2V3X A;  2B3H A;  2EVM A;  4R60 A;  3BIP A;  4IKU A;  4IPA A;  2GU7 A;  4U6E A;  2BWY A;  4A6V A;  4S00 A;  2DFI A;  1XGS A;  1C23 A;  2BWW A;  2GG2 A;  1W7V A;  2EA4 A;  1C22 A;  1WY2 A;  1Y1N A;  1JAW A;  2GG7 A;  3FMQ A;  4FO7 A;  2GU6 A;  3IU9 A;  2GG8 A;  3PKA A;  2NQ6 A;  5CLS A;  4FLJ A;  2GG3 A;  5CIK A;  4EGE A;  1WL9 A;  2BH3 A;  1YW7 A;  1C21 A;  4FO8 A;  1YVM A;  4QR8 A;  4U70 A;  1XNZ A;  3D27 A;  3L7G A;  4IKR A;  4IU6 A;  5JI6 A;  5D6E A;  4RZY A;  5CDE A;  5FCF A;  2HOW A;  4U73 A;  2GGB A;  2GTX A;  1YJ3 A;  4ZWU A;  3MX6 A;  4KM3 A;  2ZSG A;  2EVC A;  3BIQ A;  2G6P A;  4RGZ 1;  4U6C A;  1MAT A;  1KQ0 A;  1WBQ A;  1WKM A;  2BHD A;  3IU7 A;  3MAT A;  3Q6D A;  4FKC A;  4IDY A;  2GZ5 A;  4A6W A;  3FM3 A; 
#chains in the Genus database with same CATH topology
 1CHM A;  3L24 A;  1B6A A;  2EVO A;  3PKD A;  4FUK A;  4ZWP A;  2Q8K A;  3PKB A;  4Z7M A;  4FLL A;  5D6F A;  3ROR A;  1QZY A;  4OOK A;  2EA2 A;  1R58 A;  2Q95 A;  5JHU A;  2MAT A;  4IF7 A;  4FLK A;  3IG4 A;  3TAV A;  4ZNG A;  2BHB A;  1WLR A;  4S2R P;  2BWV A;  4U71 A;  2P99 A;  4S2T P;  3S6B A;  4IKT A;  1C27 A;  2Q94 A;  1C24 A;  2Q96 A;  1WL6 A;  2BHA A;  1M35 A;  2GGC A;  2B3L A;  2BHC A;  4IKS A;  1QXY A;  2ADU A;  1YW8 A;  4S01 A;  2GA2 A;  1O0X A;  4U69 A;  4U75 A;  4RZZ A;  5CNX A;  2GG0 A;  1KQ9 A;  2V3Y A;  2V6C A;  4U1B A;  1XGM A;  4U6W A;  4MAT A;  2B3K A;  1XGN A;  3PKC A;  5CDV A;  3TB5 A;  1B59 A;  3BIT A;  2IW2 A;  4U6Z A;  2GU4 A;  1R5H A;  4PNC A;  5JFR A;  4FLI A;  4HXX A;  5CE6 A;  2BN7 A;  1KP0 A;  2OKN A;  2BB7 A;  2Q92 A;  2V3Z A;  2P98 A;  2Q93 A;  4U6J A;  4IEC A;  1A16 A;  2GG5 A;  2P9A A;  1BN5 A;  2GU5 A;  3CB6 A;  1N51 A;  4JUQ A;  1BOA A;  4PV4 A;  1QXZ A;  1R5G A;  3RVA A;  3CB5 A;  2BWT A;  4ZWO A;  1QXW A;  1YW9 A;  2BWU A;  1XGO A;  2BWS A;  4B28 A;  1WN1 A;  3PKE A;  4U76 A;  5FCH A;  3MR1 A;  3CTZ A;  2OAZ A;  2NQ7 A;  1PV9 A;  2GG9 A;  3FMR A;  2BWX A;  5E5B A;  1W2M A;  3IU8 A;  5CDL A;  2V3X A;  2B3H A;  2EVM A;  4R60 A;  3BIP A;  4IKU A;  4IPA A;  2GU7 A;  4U6E A;  2BWY A;  4A6V A;  4S00 A;  2DFI A;  1XGS A;  1C23 A;  2BWW A;  2GG2 A;  1W7V A;  2EA4 A;  1C22 A;  1WY2 A;  1Y1N A;  1JAW A;  2GG7 A;  3FMQ A;  4FO7 A;  2GU6 A;  3IU9 A;  2GG8 A;  3PKA A;  2NQ6 A;  5CLS A;  4FLJ A;  2GG3 A;  5CIK A;  4EGE A;  1WL9 A;  2BH3 A;  1YW7 A;  1C21 A;  4FO8 A;  1YVM A;  4QR8 A;  4U70 A;  1XNZ A;  3D27 A;  3L7G A;  4IKR A;  4IU6 A;  5JI6 A;  5D6E A;  4RZY A;  5CDE A;  5FCF A;  2HOW A;  4U73 A;  2GGB A;  2GTX A;  1YJ3 A;  4ZWU A;  3MX6 A;  4KM3 A;  2ZSG A;  2EVC A;  3BIQ A;  2G6P A;  4RGZ 1;  4U6C A;  1MAT A;  1KQ0 A;  1WBQ A;  1WKM A;  2BHD A;  3IU7 A;  3MAT A;  3Q6D A;  4FKC A;  4IDY A;  2GZ5 A;  4A6W A;  3FM3 A; 
#chains in the Genus database with same CATH homology
 1CHM A;  3L24 A;  1B6A A;  2EVO A;  3PKD A;  4FUK A;  4ZWP A;  2Q8K A;  3PKB A;  4Z7M A;  4FLL A;  5D6F A;  3ROR A;  1QZY A;  4OOK A;  2EA2 A;  1R58 A;  2Q95 A;  5JHU A;  2MAT A;  4IF7 A;  4FLK A;  3IG4 A;  3TAV A;  4ZNG A;  2BHB A;  1WLR A;  4S2R P;  2BWV A;  4U71 A;  2P99 A;  4S2T P;  3S6B A;  4IKT A;  1C27 A;  2Q94 A;  1C24 A;  2Q96 A;  1WL6 A;  2BHA A;  1M35 A;  2GGC A;  2B3L A;  2BHC A;  4IKS A;  1QXY A;  2ADU A;  1YW8 A;  4S01 A;  2GA2 A;  1O0X A;  4U69 A;  4U75 A;  4RZZ A;  5CNX A;  2GG0 A;  1KQ9 A;  2V3Y A;  2V6C A;  4U1B A;  1XGM A;  4U6W A;  4MAT A;  2B3K A;  1XGN A;  3PKC A;  5CDV A;  3TB5 A;  1B59 A;  3BIT A;  2IW2 A;  4U6Z A;  2GU4 A;  1R5H A;  4PNC A;  5JFR A;  4FLI A;  4HXX A;  5CE6 A;  2BN7 A;  1KP0 A;  2OKN A;  2BB7 A;  2Q92 A;  2V3Z A;  2P98 A;  2Q93 A;  4U6J A;  4IEC A;  1A16 A;  2GG5 A;  2P9A A;  1BN5 A;  2GU5 A;  3CB6 A;  1N51 A;  4JUQ A;  1BOA A;  4PV4 A;  1QXZ A;  1R5G A;  3RVA A;  3CB5 A;  2BWT A;  4ZWO A;  1QXW A;  1YW9 A;  2BWU A;  1XGO A;  2BWS A;  4B28 A;  1WN1 A;  3PKE A;  4U76 A;  5FCH A;  3MR1 A;  3CTZ A;  2OAZ A;  2NQ7 A;  1PV9 A;  2GG9 A;  3FMR A;  2BWX A;  5E5B A;  1W2M A;  3IU8 A;  5CDL A;  2V3X A;  2B3H A;  2EVM A;  4R60 A;  3BIP A;  4IKU A;  4IPA A;  2GU7 A;  4U6E A;  2BWY A;  4A6V A;  4S00 A;  2DFI A;  1XGS A;  1C23 A;  2BWW A;  2GG2 A;  1W7V A;  2EA4 A;  1C22 A;  1WY2 A;  1Y1N A;  1JAW A;  2GG7 A;  3FMQ A;  4FO7 A;  2GU6 A;  3IU9 A;  2GG8 A;  3PKA A;  2NQ6 A;  5CLS A;  4FLJ A;  2GG3 A;  5CIK A;  4EGE A;  1WL9 A;  2BH3 A;  1YW7 A;  1C21 A;  4FO8 A;  1YVM A;  4QR8 A;  4U70 A;  1XNZ A;  3D27 A;  3L7G A;  4IKR A;  4IU6 A;  5JI6 A;  5D6E A;  4RZY A;  5CDE A;  5FCF A;  2HOW A;  4U73 A;  2GGB A;  2GTX A;  1YJ3 A;  4ZWU A;  3MX6 A;  4KM3 A;  2ZSG A;  2EVC A;  3BIQ A;  2G6P A;  4RGZ 1;  4U6C A;  1MAT A;  1KQ0 A;  1WBQ A;  1WKM A;  2BHD A;  3IU7 A;  3MAT A;  3Q6D A;  4FKC A;  4IDY A;  2GZ5 A;  4A6W A;  3FM3 A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite