4IDYA

Mycobacterium tuberculosis methionine aminopeptidase type 1c in complex with 2-hydroxyethyl disulfide
Total Genus 87
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
281
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase 2
publication title Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 87
structure length 281
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-12-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4idyA01
4FKCA 4IU6A 4U70A 3PKCA 2BHDA 1PV9A 1YJ3A 2B3KA 2GGCA 4IKTA 4U75A 3FMRA 3FMQA 2BHBA 2ADUA 2V3XA 4IDYA 2BWVA 1YVMA 2BHCA 2GU7A 5CE6A 1W7VA 4Z7MA 1BOAA 2Q93A 3RORA 1XGOA 5FCHA 1XNZA 2OAZA 4U71A 4RGZ1 1M35A 5CIKA 2GG9A 1YW7A 2GU5A 5JHUA 2BHAA 4RZZA 4U76A 1C24A 1WBQA 1N51A 2BWSA 3BITA 4FLIA 4ZWOA 2BWXA 3TB5A 4U6CA 3PKBA 2HOWA 4FO8A 1WL9A 1B59A 1R58A 3S6BA 1R5GA 3IG4A 4ZWPA 4ZWUA 4FUKA 4IKRA 2Q96A 4U6JA 2P99A 4U1BA 2GU6A 4S2TP 1XGMA 1MATA 2V3YA 2BN7A 3CB5A 4RZYA 5CDEA 5CLSA 2GG7A 3D27A 2B3LA 1JAWA 4U6EA 4A6VA 2ZSGA 2GA2A 1WN1A 2P9AA 4U6WA 3L24A 5E5BA 5CDVA 1C23A 1XGSA 1BN5A 1QXWA 3FM3A 3L7GA 5JFRA 2BWUA 1Y1NA 1QXZA 1XGNA 2P98A 4ZNGA 3PKEA 2EVOA 3MR1A 2Q94A 3Q6DA 1WL6A 1WKMA 2GZ5A 4U69A 5D6FA 4S2RP 4IKSA 4HXXA 1KQ0A 2EA2A 4KM3A 1QXYA 2V3ZA 1A16A 4FO7A 4MATA 3CTZA 1R5HA 1KQ9A 4FLKA 2NQ6A 4B28A 2G6PA 3MATA 2Q92A 4FLLA 1CHMA 2EVMA 2GGBA 5FCFA 1C21A 2GG0A 2MATA 3CB6A 4U73A 1C27A 3IU8A 1W2MA 1O0XA 3PKDA 1B6AA 4S01A 3IU7A 3BIQA 2GG2A 4IF7A 4PV4A 3RVAA 4S00A 1WY2A 2BB7A 1WLRA 2Q95A 4FLJA 2BWTA 2EVCA 1C22A 5JI6A 2GU4A 4QR8A 2GG8A 1KP0A 2IW2A 2NQ7A 4EGEA 4A6WA 1YW9A 1YW8A 3BIPA 2EA4A 4PNCA 2GTXA 3MX6A 2B3HA 4OOKA 4IECA 2GG5A 3TAVA 3PKAA 2DFIA 4U6ZA 2BH3A 3IU9A 5CNXA 4R60A 5D6EA 4JUQA 2OKNA 2BWYA 2GG3A 2V6CA 2BWWA 1QZYA 4IKUA 4IPAA 2Q8KA 5CDLA
chains in the Genus database with same CATH superfamily
4FKCA 4IU6A 4U70A 3PKCA 2BHDA 1PV9A 1YJ3A 2B3KA 2GGCA 4IKTA 4U75A 3FMRA 3FMQA 2BHBA 2ADUA 2V3XA 4IDYA 2BWVA 1YVMA 2BHCA 2GU7A 5CE6A 1W7VA 4Z7MA 1BOAA 2Q93A 3RORA 1XGOA 5FCHA 1XNZA 2OAZA 4U71A 4RGZ1 1M35A 5CIKA 2GG9A 1YW7A 2GU5A 5JHUA 2BHAA 4RZZA 4U76A 1C24A 1WBQA 1N51A 2BWSA 3BITA 4FLIA 4ZWOA 2BWXA 3TB5A 4U6CA 3PKBA 2HOWA 4FO8A 1WL9A 1B59A 1R58A 3S6BA 1R5GA 3IG4A 4ZWPA 4ZWUA 4FUKA 4IKRA 2Q96A 4U6JA 2P99A 4U1BA 2GU6A 4S2TP 1XGMA 1MATA 2V3YA 2BN7A 3CB5A 4RZYA 5CDEA 5CLSA 2GG7A 3D27A 2B3LA 1JAWA 4U6EA 4A6VA 2ZSGA 2GA2A 1WN1A 2P9AA 4U6WA 3L24A 5E5BA 5CDVA 1C23A 1XGSA 1BN5A 1QXWA 3FM3A 3L7GA 5JFRA 2BWUA 1Y1NA 1QXZA 1XGNA 2P98A 4ZNGA 3PKEA 2EVOA 3MR1A 2Q94A 3Q6DA 1WL6A 1WKMA 2GZ5A 4U69A 5D6FA 4S2RP 4IKSA 4HXXA 1KQ0A 2EA2A 4KM3A 1QXYA 2V3ZA 1A16A 4FO7A 4MATA 3CTZA 1R5HA 1KQ9A 4FLKA 2NQ6A 4B28A 2G6PA 3MATA 2Q92A 4FLLA 1CHMA 2EVMA 2GGBA 5FCFA 1C21A 2GG0A 2MATA 3CB6A 4U73A 1C27A 3IU8A 1W2MA 1O0XA 3PKDA 1B6AA 4S01A 3IU7A 3BIQA 2GG2A 4IF7A 4PV4A 3RVAA 4S00A 1WY2A 2BB7A 1WLRA 2Q95A 4FLJA 2BWTA 2EVCA 1C22A 5JI6A 2GU4A 4QR8A 2GG8A 1KP0A 2IW2A 2NQ7A 4EGEA 4A6WA 1YW9A 1YW8A 3BIPA 2EA4A 4PNCA 2GTXA 3MX6A 2B3HA 4OOKA 4IECA 2GG5A 3TAVA 3PKAA 2DFIA 4U6ZA 2BH3A 3IU9A 5CNXA 4R60A 5D6EA 4JUQA 2OKNA 2BWYA 2GG3A 2V6CA 2BWWA 1QZYA 4IKUA 4IPAA 2Q8KA 5CDLA
chains in the Genus database with same CATH topology
4FKCA 4IU6A 4U70A 3PKCA 2BHDA 1PV9A 1YJ3A 2B3KA 2GGCA 4IKTA 4U75A 3FMRA 3FMQA 2BHBA 2ADUA 2V3XA 4IDYA 2BWVA 1YVMA 2BHCA 2GU7A 5CE6A 1W7VA 4Z7MA 1BOAA 2Q93A 3RORA 1XGOA 5FCHA 1XNZA 2OAZA 4U71A 4RGZ1 1M35A 5CIKA 2GG9A 1YW7A 2GU5A 5JHUA 2BHAA 4RZZA 4U76A 1C24A 1WBQA 1N51A 2BWSA 3BITA 4FLIA 4ZWOA 2BWXA 3TB5A 4U6CA 3PKBA 2HOWA 4FO8A 1WL9A 1B59A 1R58A 3S6BA 1R5GA 3IG4A 4ZWPA 4ZWUA 4FUKA 4IKRA 2Q96A 4U6JA 2P99A 4U1BA 2GU6A 4S2TP 1XGMA 1MATA 2V3YA 2BN7A 3CB5A 4RZYA 5CDEA 5CLSA 2GG7A 3D27A 2B3LA 1JAWA 4U6EA 4A6VA 2ZSGA 2GA2A 1WN1A 2P9AA 4U6WA 3L24A 5E5BA 5CDVA 1C23A 1XGSA 1BN5A 1QXWA 3FM3A 3L7GA 5JFRA 2BWUA 1Y1NA 1QXZA 1XGNA 2P98A 4ZNGA 3PKEA 2EVOA 3MR1A 2Q94A 3Q6DA 1WL6A 1WKMA 2GZ5A 4U69A 5D6FA 4S2RP 4IKSA 4HXXA 1KQ0A 2EA2A 4KM3A 1QXYA 2V3ZA 1A16A 4FO7A 4MATA 3CTZA 1R5HA 1KQ9A 4FLKA 2NQ6A 4B28A 2G6PA 3MATA 2Q92A 4FLLA 1CHMA 2EVMA 2GGBA 5FCFA 1C21A 2GG0A 2MATA 3CB6A 4U73A 1C27A 3IU8A 1W2MA 1O0XA 3PKDA 1B6AA 4S01A 3IU7A 3BIQA 2GG2A 4IF7A 4PV4A 3RVAA 4S00A 1WY2A 2BB7A 1WLRA 2Q95A 4FLJA 2BWTA 2EVCA 1C22A 5JI6A 2GU4A 4QR8A 2GG8A 1KP0A 2IW2A 2NQ7A 4EGEA 4A6WA 1YW9A 1YW8A 3BIPA 2EA4A 4PNCA 2GTXA 3MX6A 2B3HA 4OOKA 4IECA 2GG5A 3TAVA 3PKAA 2DFIA 4U6ZA 2BH3A 3IU9A 5CNXA 4R60A 5D6EA 4JUQA 2OKNA 2BWYA 2GG3A 2V6CA 2BWWA 1QZYA 4IKUA 4IPAA 2Q8KA 5CDLA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FKC A;  4IU6 A;  4U70 A;  3PKC A;  2BHD A;  1PV9 A;  1YJ3 A;  2B3K A;  2GGC A;  4IKT A;  4U75 A;  3FMR A;  3FMQ A;  2BHB A;  2ADU A;  2V3X A;  4IDY A;  2BWV A;  1YVM A;  2BHC A;  2GU7 A;  5CE6 A;  1W7V A;  4Z7M A;  1BOA A;  2Q93 A;  3ROR A;  1XGO A;  5FCH A;  1XNZ A;  2OAZ A;  4U71 A;  4RGZ 1;  1M35 A;  5CIK A;  2GG9 A;  1YW7 A;  2GU5 A;  5JHU A;  2BHA A;  4RZZ A;  4U76 A;  1C24 A;  1WBQ A;  1N51 A;  2BWS A;  3BIT A;  4FLI A;  4ZWO A;  2BWX A;  3TB5 A;  4U6C A;  3PKB A;  2HOW A;  4FO8 A;  1WL9 A;  1B59 A;  1R58 A;  3S6B A;  1R5G A;  3IG4 A;  4ZWP A;  4ZWU A;  4FUK A;  4IKR A;  2Q96 A;  4U6J A;  2P99 A;  4U1B A;  2GU6 A;  4S2T P;  1XGM A;  1MAT A;  2V3Y A;  2BN7 A;  3CB5 A;  4RZY A;  5CDE A;  5CLS A;  2GG7 A;  3D27 A;  2B3L A;  1JAW A;  4U6E A;  4A6V A;  2ZSG A;  2GA2 A;  1WN1 A;  2P9A A;  4U6W A;  3L24 A;  5E5B A;  5CDV A;  1C23 A;  1XGS A;  1BN5 A;  1QXW A;  3FM3 A;  3L7G A;  5JFR A;  2BWU A;  1Y1N A;  1QXZ A;  1XGN A;  2P98 A;  4ZNG A;  3PKE A;  2EVO A;  3MR1 A;  2Q94 A;  3Q6D A;  1WL6 A;  1WKM A;  2GZ5 A;  4U69 A;  5D6F A;  4S2R P;  4IKS A;  4HXX A;  1KQ0 A;  2EA2 A;  4KM3 A;  1QXY A;  2V3Z A;  1A16 A;  4FO7 A;  4MAT A;  3CTZ A;  1R5H A;  1KQ9 A;  4FLK A;  2NQ6 A;  4B28 A;  2G6P A;  3MAT A;  2Q92 A;  4FLL A;  1CHM A;  2EVM A;  2GGB A;  5FCF A;  1C21 A;  2GG0 A;  2MAT A;  3CB6 A;  4U73 A;  1C27 A;  3IU8 A;  1W2M A;  1O0X A;  3PKD A;  1B6A A;  4S01 A;  3IU7 A;  3BIQ A;  2GG2 A;  4IF7 A;  4PV4 A;  3RVA A;  4S00 A;  1WY2 A;  2BB7 A;  1WLR A;  2Q95 A;  4FLJ A;  2BWT A;  2EVC A;  1C22 A;  5JI6 A;  2GU4 A;  4QR8 A;  2GG8 A;  1KP0 A;  2IW2 A;  2NQ7 A;  4EGE A;  4A6W A;  1YW9 A;  1YW8 A;  3BIP A;  2EA4 A;  4PNC A;  2GTX A;  3MX6 A;  2B3H A;  4OOK A;  4IEC A;  2GG5 A;  3TAV A;  3PKA A;  2DFI A;  4U6Z A;  2BH3 A;  3IU9 A;  5CNX A;  4R60 A;  5D6E A;  4JUQ A;  2OKN A;  2BWY A;  2GG3 A;  2V6C A;  2BWW A;  1QZY A;  4IKU A;  4IPA A;  2Q8K A;  5CDL A; 
#chains in the Genus database with same CATH topology
 4FKC A;  4IU6 A;  4U70 A;  3PKC A;  2BHD A;  1PV9 A;  1YJ3 A;  2B3K A;  2GGC A;  4IKT A;  4U75 A;  3FMR A;  3FMQ A;  2BHB A;  2ADU A;  2V3X A;  4IDY A;  2BWV A;  1YVM A;  2BHC A;  2GU7 A;  5CE6 A;  1W7V A;  4Z7M A;  1BOA A;  2Q93 A;  3ROR A;  1XGO A;  5FCH A;  1XNZ A;  2OAZ A;  4U71 A;  4RGZ 1;  1M35 A;  5CIK A;  2GG9 A;  1YW7 A;  2GU5 A;  5JHU A;  2BHA A;  4RZZ A;  4U76 A;  1C24 A;  1WBQ A;  1N51 A;  2BWS A;  3BIT A;  4FLI A;  4ZWO A;  2BWX A;  3TB5 A;  4U6C A;  3PKB A;  2HOW A;  4FO8 A;  1WL9 A;  1B59 A;  1R58 A;  3S6B A;  1R5G A;  3IG4 A;  4ZWP A;  4ZWU A;  4FUK A;  4IKR A;  2Q96 A;  4U6J A;  2P99 A;  4U1B A;  2GU6 A;  4S2T P;  1XGM A;  1MAT A;  2V3Y A;  2BN7 A;  3CB5 A;  4RZY A;  5CDE A;  5CLS A;  2GG7 A;  3D27 A;  2B3L A;  1JAW A;  4U6E A;  4A6V A;  2ZSG A;  2GA2 A;  1WN1 A;  2P9A A;  4U6W A;  3L24 A;  5E5B A;  5CDV A;  1C23 A;  1XGS A;  1BN5 A;  1QXW A;  3FM3 A;  3L7G A;  5JFR A;  2BWU A;  1Y1N A;  1QXZ A;  1XGN A;  2P98 A;  4ZNG A;  3PKE A;  2EVO A;  3MR1 A;  2Q94 A;  3Q6D A;  1WL6 A;  1WKM A;  2GZ5 A;  4U69 A;  5D6F A;  4S2R P;  4IKS A;  4HXX A;  1KQ0 A;  2EA2 A;  4KM3 A;  1QXY A;  2V3Z A;  1A16 A;  4FO7 A;  4MAT A;  3CTZ A;  1R5H A;  1KQ9 A;  4FLK A;  2NQ6 A;  4B28 A;  2G6P A;  3MAT A;  2Q92 A;  4FLL A;  1CHM A;  2EVM A;  2GGB A;  5FCF A;  1C21 A;  2GG0 A;  2MAT A;  3CB6 A;  4U73 A;  1C27 A;  3IU8 A;  1W2M A;  1O0X A;  3PKD A;  1B6A A;  4S01 A;  3IU7 A;  3BIQ A;  2GG2 A;  4IF7 A;  4PV4 A;  3RVA A;  4S00 A;  1WY2 A;  2BB7 A;  1WLR A;  2Q95 A;  4FLJ A;  2BWT A;  2EVC A;  1C22 A;  5JI6 A;  2GU4 A;  4QR8 A;  2GG8 A;  1KP0 A;  2IW2 A;  2NQ7 A;  4EGE A;  4A6W A;  1YW9 A;  1YW8 A;  3BIP A;  2EA4 A;  4PNC A;  2GTX A;  3MX6 A;  2B3H A;  4OOK A;  4IEC A;  2GG5 A;  3TAV A;  3PKA A;  2DFI A;  4U6Z A;  2BH3 A;  3IU9 A;  5CNX A;  4R60 A;  5D6E A;  4JUQ A;  2OKN A;  2BWY A;  2GG3 A;  2V6C A;  2BWW A;  1QZY A;  4IKU A;  4IPA A;  2Q8K A;  5CDL A; 
#chains in the Genus database with same CATH homology
 4FKC A;  4IU6 A;  4U70 A;  3PKC A;  2BHD A;  1PV9 A;  1YJ3 A;  2B3K A;  2GGC A;  4IKT A;  4U75 A;  3FMR A;  3FMQ A;  2BHB A;  2ADU A;  2V3X A;  4IDY A;  2BWV A;  1YVM A;  2BHC A;  2GU7 A;  5CE6 A;  1W7V A;  4Z7M A;  1BOA A;  2Q93 A;  3ROR A;  1XGO A;  5FCH A;  1XNZ A;  2OAZ A;  4U71 A;  4RGZ 1;  1M35 A;  5CIK A;  2GG9 A;  1YW7 A;  2GU5 A;  5JHU A;  2BHA A;  4RZZ A;  4U76 A;  1C24 A;  1WBQ A;  1N51 A;  2BWS A;  3BIT A;  4FLI A;  4ZWO A;  2BWX A;  3TB5 A;  4U6C A;  3PKB A;  2HOW A;  4FO8 A;  1WL9 A;  1B59 A;  1R58 A;  3S6B A;  1R5G A;  3IG4 A;  4ZWP A;  4ZWU A;  4FUK A;  4IKR A;  2Q96 A;  4U6J A;  2P99 A;  4U1B A;  2GU6 A;  4S2T P;  1XGM A;  1MAT A;  2V3Y A;  2BN7 A;  3CB5 A;  4RZY A;  5CDE A;  5CLS A;  2GG7 A;  3D27 A;  2B3L A;  1JAW A;  4U6E A;  4A6V A;  2ZSG A;  2GA2 A;  1WN1 A;  2P9A A;  4U6W A;  3L24 A;  5E5B A;  5CDV A;  1C23 A;  1XGS A;  1BN5 A;  1QXW A;  3FM3 A;  3L7G A;  5JFR A;  2BWU A;  1Y1N A;  1QXZ A;  1XGN A;  2P98 A;  4ZNG A;  3PKE A;  2EVO A;  3MR1 A;  2Q94 A;  3Q6D A;  1WL6 A;  1WKM A;  2GZ5 A;  4U69 A;  5D6F A;  4S2R P;  4IKS A;  4HXX A;  1KQ0 A;  2EA2 A;  4KM3 A;  1QXY A;  2V3Z A;  1A16 A;  4FO7 A;  4MAT A;  3CTZ A;  1R5H A;  1KQ9 A;  4FLK A;  2NQ6 A;  4B28 A;  2G6P A;  3MAT A;  2Q92 A;  4FLL A;  1CHM A;  2EVM A;  2GGB A;  5FCF A;  1C21 A;  2GG0 A;  2MAT A;  3CB6 A;  4U73 A;  1C27 A;  3IU8 A;  1W2M A;  1O0X A;  3PKD A;  1B6A A;  4S01 A;  3IU7 A;  3BIQ A;  2GG2 A;  4IF7 A;  4PV4 A;  3RVA A;  4S00 A;  1WY2 A;  2BB7 A;  1WLR A;  2Q95 A;  4FLJ A;  2BWT A;  2EVC A;  1C22 A;  5JI6 A;  2GU4 A;  4QR8 A;  2GG8 A;  1KP0 A;  2IW2 A;  2NQ7 A;  4EGE A;  4A6W A;  1YW9 A;  1YW8 A;  3BIP A;  2EA4 A;  4PNC A;  2GTX A;  3MX6 A;  2B3H A;  4OOK A;  4IEC A;  2GG5 A;  3TAV A;  3PKA A;  2DFI A;  4U6Z A;  2BH3 A;  3IU9 A;  5CNX A;  4R60 A;  5D6E A;  4JUQ A;  2OKN A;  2BWY A;  2GG3 A;  2V6C A;  2BWW A;  1QZY A;  4IKU A;  4IPA A;  2Q8K A;  5CDL A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...