4IDYA

Mycobacterium tuberculosis methionine aminopeptidase type 1c in complex with 2-hydroxyethyl disulfide
Total Genus 87
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
281
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTL'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Methionine aminopeptidase 2
publication title Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 87
structure length 281
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-12-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4idyA01
2GG0A 5D6FA 2BHCA 1W2MA 5CIKA 4FLLA 4Z7MA 1PV9A 4RZYA 2GG5A 5CDEA 2BWVA 1B6AA 2P98A 2B3HA 2BWTA 4U76A 5JFRA 3PKBA 4S00A 1KQ9A 2EVOA 2GZ5A 2V6CA 4IKSA 4U6EA 4A6WA 1R58A 1YW7A 1C24A 2EA2A 1W7VA 4U6JA 4EGEA 5CNXA 2GU5A 5CDVA 2BN7A 3MATA 4FKCA 2GA2A 3MX6A 5JI6A 1XGOA 4IF7A 3CTZA 3D27A 1KP0A 2BB7A 4B28A 2BHDA 2V3ZA 4KM3A 2OKNA 4FLJA 3L24A 2GG3A 2BHAA 4U71A 3PKDA 4IKTA 2ZSGA 1R5GA 4U69A 4FUKA 2NQ7A 4R60A 3PKEA 3FM3A 1JAWA 2G6PA 1WKMA 1WL6A 4U70A 5CLSA 2GTXA 2NQ6A 2IW2A 3Q6DA 3IU8A 1WN1A 4U6WA 1N51A 3FMQA 2GU4A 4U73A 4IKUA 2BWXA 4RGZ1 3RVAA 1XGMA 1M35A 2Q96A 4FO7A 2GG9A 4QR8A 4U75A 4IPAA 4U1BA 1A16A 4ZNGA 2GU7A 2GG8A 4RZZA 2Q93A 4ZWOA 3MR1A 5D6EA 1Y1NA 1B59A 2V3YA 4PNCA 2P99A 4PV4A 4IECA 2GU6A 3PKAA 1C22A 4MATA 3RORA 4HXXA 2Q8KA 3IG4A 3BIPA 1XGSA 2HOWA 4U6ZA 3BITA 3BIQA 4FLKA 2EVCA 4ZWPA 2V3XA 4S01A 1C27A 1QXZA 1C21A 1YW9A 5CE6A 2B3LA 5FCHA 2MATA 1CHMA 4FLIA 4OOKA 4U6CA 5FCFA 1KQ0A 2GG7A 3IU9A 1BN5A 1R5HA 4ZWUA 2BWWA 1QZYA 1WBQA 1MATA 3PKCA 4IU6A 3CB5A 1C23A 2Q92A 3IU7A 2Q94A 1QXWA 2BWYA 2GGBA 5JHUA 2DFIA 4S2RP 1WL9A 2BWSA 1O0XA 4A6VA 2OAZA 4FO8A 3TB5A 5E5BA 2BWUA 1WLRA 2B3KA 2EVMA 1YJ3A 1XNZA 1WY2A 1YW8A 2EA4A 1BOAA 3L7GA 2ADUA 2GGCA 3FMRA 2GG2A 4IDYA 1YVMA 3S6BA 1QXYA 2BH3A 4S2TP 2P9AA 4JUQA 5CDLA 3CB6A 3TAVA 2BHBA 2Q95A 1XGNA 4IKRA
chains in the Genus database with same CATH superfamily
2GG0A 5D6FA 2BHCA 1W2MA 5CIKA 4FLLA 4Z7MA 1PV9A 4RZYA 2GG5A 5CDEA 2BWVA 1B6AA 2P98A 2B3HA 2BWTA 4U76A 5JFRA 3PKBA 4S00A 1KQ9A 2EVOA 2GZ5A 2V6CA 4IKSA 4U6EA 4A6WA 1R58A 1YW7A 1C24A 2EA2A 1W7VA 4U6JA 4EGEA 5CNXA 2GU5A 5CDVA 2BN7A 3MATA 4FKCA 2GA2A 3MX6A 5JI6A 1XGOA 4IF7A 3CTZA 3D27A 1KP0A 2BB7A 4B28A 2BHDA 2V3ZA 4KM3A 2OKNA 4FLJA 3L24A 2GG3A 2BHAA 4U71A 3PKDA 4IKTA 2ZSGA 1R5GA 4U69A 4FUKA 2NQ7A 4R60A 3PKEA 3FM3A 1JAWA 2G6PA 1WKMA 1WL6A 4U70A 5CLSA 2GTXA 2NQ6A 2IW2A 3Q6DA 3IU8A 1WN1A 4U6WA 1N51A 3FMQA 2GU4A 4U73A 4IKUA 2BWXA 4RGZ1 3RVAA 1XGMA 1M35A 2Q96A 4FO7A 2GG9A 4QR8A 4U75A 4IPAA 4U1BA 1A16A 4ZNGA 2GU7A 2GG8A 4RZZA 2Q93A 4ZWOA 3MR1A 5D6EA 1Y1NA 1B59A 2V3YA 4PNCA 2P99A 4PV4A 4IECA 2GU6A 3PKAA 1C22A 4MATA 3RORA 4HXXA 2Q8KA 3IG4A 3BIPA 1XGSA 2HOWA 4U6ZA 3BITA 3BIQA 4FLKA 2EVCA 4ZWPA 2V3XA 4S01A 1C27A 1QXZA 1C21A 1YW9A 5CE6A 2B3LA 5FCHA 2MATA 1CHMA 4FLIA 4OOKA 4U6CA 5FCFA 1KQ0A 2GG7A 3IU9A 1BN5A 1R5HA 4ZWUA 2BWWA 1QZYA 1WBQA 1MATA 3PKCA 4IU6A 3CB5A 1C23A 2Q92A 3IU7A 2Q94A 1QXWA 2BWYA 2GGBA 5JHUA 2DFIA 4S2RP 1WL9A 2BWSA 1O0XA 4A6VA 2OAZA 4FO8A 3TB5A 5E5BA 2BWUA 1WLRA 2B3KA 2EVMA 1YJ3A 1XNZA 1WY2A 1YW8A 2EA4A 1BOAA 3L7GA 2ADUA 2GGCA 3FMRA 2GG2A 4IDYA 1YVMA 3S6BA 1QXYA 2BH3A 4S2TP 2P9AA 4JUQA 5CDLA 3CB6A 3TAVA 2BHBA 2Q95A 1XGNA 4IKRA
chains in the Genus database with same CATH topology
2GG0A 5D6FA 2BHCA 1W2MA 5CIKA 4FLLA 4Z7MA 1PV9A 4RZYA 2GG5A 5CDEA 2BWVA 1B6AA 2P98A 2B3HA 2BWTA 4U76A 5JFRA 3PKBA 4S00A 1KQ9A 2EVOA 2GZ5A 2V6CA 4IKSA 4U6EA 4A6WA 1R58A 1YW7A 1C24A 2EA2A 1W7VA 4U6JA 4EGEA 5CNXA 2GU5A 5CDVA 2BN7A 3MATA 4FKCA 2GA2A 3MX6A 5JI6A 1XGOA 4IF7A 3CTZA 3D27A 1KP0A 2BB7A 4B28A 2BHDA 2V3ZA 4KM3A 2OKNA 4FLJA 3L24A 2GG3A 2BHAA 4U71A 3PKDA 4IKTA 2ZSGA 1R5GA 4U69A 4FUKA 2NQ7A 4R60A 3PKEA 3FM3A 1JAWA 2G6PA 1WKMA 1WL6A 4U70A 5CLSA 2GTXA 2NQ6A 2IW2A 3Q6DA 3IU8A 1WN1A 4U6WA 1N51A 3FMQA 2GU4A 4U73A 4IKUA 2BWXA 4RGZ1 3RVAA 1XGMA 1M35A 2Q96A 4FO7A 2GG9A 4QR8A 4U75A 4IPAA 4U1BA 1A16A 4ZNGA 2GU7A 2GG8A 4RZZA 2Q93A 4ZWOA 3MR1A 5D6EA 1Y1NA 1B59A 2V3YA 4PNCA 2P99A 4PV4A 4IECA 2GU6A 3PKAA 1C22A 4MATA 3RORA 4HXXA 2Q8KA 3IG4A 3BIPA 1XGSA 2HOWA 4U6ZA 3BITA 3BIQA 4FLKA 2EVCA 4ZWPA 2V3XA 4S01A 1C27A 1QXZA 1C21A 1YW9A 5CE6A 2B3LA 5FCHA 2MATA 1CHMA 4FLIA 4OOKA 4U6CA 5FCFA 1KQ0A 2GG7A 3IU9A 1BN5A 1R5HA 4ZWUA 2BWWA 1QZYA 1WBQA 1MATA 3PKCA 4IU6A 3CB5A 1C23A 2Q92A 3IU7A 2Q94A 1QXWA 2BWYA 2GGBA 5JHUA 2DFIA 4S2RP 1WL9A 2BWSA 1O0XA 4A6VA 2OAZA 4FO8A 3TB5A 5E5BA 2BWUA 1WLRA 2B3KA 2EVMA 1YJ3A 1XNZA 1WY2A 1YW8A 2EA4A 1BOAA 3L7GA 2ADUA 2GGCA 3FMRA 2GG2A 4IDYA 1YVMA 3S6BA 1QXYA 2BH3A 4S2TP 2P9AA 4JUQA 5CDLA 3CB6A 3TAVA 2BHBA 2Q95A 1XGNA 4IKRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG0 A;  5D6F A;  2BHC A;  1W2M A;  5CIK A;  4FLL A;  4Z7M A;  1PV9 A;  4RZY A;  2GG5 A;  5CDE A;  2BWV A;  1B6A A;  2P98 A;  2B3H A;  2BWT A;  4U76 A;  5JFR A;  3PKB A;  4S00 A;  1KQ9 A;  2EVO A;  2GZ5 A;  2V6C A;  4IKS A;  4U6E A;  4A6W A;  1R58 A;  1YW7 A;  1C24 A;  2EA2 A;  1W7V A;  4U6J A;  4EGE A;  5CNX A;  2GU5 A;  5CDV A;  2BN7 A;  3MAT A;  4FKC A;  2GA2 A;  3MX6 A;  5JI6 A;  1XGO A;  4IF7 A;  3CTZ A;  3D27 A;  1KP0 A;  2BB7 A;  4B28 A;  2BHD A;  2V3Z A;  4KM3 A;  2OKN A;  4FLJ A;  3L24 A;  2GG3 A;  2BHA A;  4U71 A;  3PKD A;  4IKT A;  2ZSG A;  1R5G A;  4U69 A;  4FUK A;  2NQ7 A;  4R60 A;  3PKE A;  3FM3 A;  1JAW A;  2G6P A;  1WKM A;  1WL6 A;  4U70 A;  5CLS A;  2GTX A;  2NQ6 A;  2IW2 A;  3Q6D A;  3IU8 A;  1WN1 A;  4U6W A;  1N51 A;  3FMQ A;  2GU4 A;  4U73 A;  4IKU A;  2BWX A;  4RGZ 1;  3RVA A;  1XGM A;  1M35 A;  2Q96 A;  4FO7 A;  2GG9 A;  4QR8 A;  4U75 A;  4IPA A;  4U1B A;  1A16 A;  4ZNG A;  2GU7 A;  2GG8 A;  4RZZ A;  2Q93 A;  4ZWO A;  3MR1 A;  5D6E A;  1Y1N A;  1B59 A;  2V3Y A;  4PNC A;  2P99 A;  4PV4 A;  4IEC A;  2GU6 A;  3PKA A;  1C22 A;  4MAT A;  3ROR A;  4HXX A;  2Q8K A;  3IG4 A;  3BIP A;  1XGS A;  2HOW A;  4U6Z A;  3BIT A;  3BIQ A;  4FLK A;  2EVC A;  4ZWP A;  2V3X A;  4S01 A;  1C27 A;  1QXZ A;  1C21 A;  1YW9 A;  5CE6 A;  2B3L A;  5FCH A;  2MAT A;  1CHM A;  4FLI A;  4OOK A;  4U6C A;  5FCF A;  1KQ0 A;  2GG7 A;  3IU9 A;  1BN5 A;  1R5H A;  4ZWU A;  2BWW A;  1QZY A;  1WBQ A;  1MAT A;  3PKC A;  4IU6 A;  3CB5 A;  1C23 A;  2Q92 A;  3IU7 A;  2Q94 A;  1QXW A;  2BWY A;  2GGB A;  5JHU A;  2DFI A;  4S2R P;  1WL9 A;  2BWS A;  1O0X A;  4A6V A;  2OAZ A;  4FO8 A;  3TB5 A;  5E5B A;  2BWU A;  1WLR A;  2B3K A;  2EVM A;  1YJ3 A;  1XNZ A;  1WY2 A;  1YW8 A;  2EA4 A;  1BOA A;  3L7G A;  2ADU A;  2GGC A;  3FMR A;  2GG2 A;  4IDY A;  1YVM A;  3S6B A;  1QXY A;  2BH3 A;  4S2T P;  2P9A A;  4JUQ A;  5CDL A;  3CB6 A;  3TAV A;  2BHB A;  2Q95 A;  1XGN A;  4IKR A; 
#chains in the Genus database with same CATH topology
 2GG0 A;  5D6F A;  2BHC A;  1W2M A;  5CIK A;  4FLL A;  4Z7M A;  1PV9 A;  4RZY A;  2GG5 A;  5CDE A;  2BWV A;  1B6A A;  2P98 A;  2B3H A;  2BWT A;  4U76 A;  5JFR A;  3PKB A;  4S00 A;  1KQ9 A;  2EVO A;  2GZ5 A;  2V6C A;  4IKS A;  4U6E A;  4A6W A;  1R58 A;  1YW7 A;  1C24 A;  2EA2 A;  1W7V A;  4U6J A;  4EGE A;  5CNX A;  2GU5 A;  5CDV A;  2BN7 A;  3MAT A;  4FKC A;  2GA2 A;  3MX6 A;  5JI6 A;  1XGO A;  4IF7 A;  3CTZ A;  3D27 A;  1KP0 A;  2BB7 A;  4B28 A;  2BHD A;  2V3Z A;  4KM3 A;  2OKN A;  4FLJ A;  3L24 A;  2GG3 A;  2BHA A;  4U71 A;  3PKD A;  4IKT A;  2ZSG A;  1R5G A;  4U69 A;  4FUK A;  2NQ7 A;  4R60 A;  3PKE A;  3FM3 A;  1JAW A;  2G6P A;  1WKM A;  1WL6 A;  4U70 A;  5CLS A;  2GTX A;  2NQ6 A;  2IW2 A;  3Q6D A;  3IU8 A;  1WN1 A;  4U6W A;  1N51 A;  3FMQ A;  2GU4 A;  4U73 A;  4IKU A;  2BWX A;  4RGZ 1;  3RVA A;  1XGM A;  1M35 A;  2Q96 A;  4FO7 A;  2GG9 A;  4QR8 A;  4U75 A;  4IPA A;  4U1B A;  1A16 A;  4ZNG A;  2GU7 A;  2GG8 A;  4RZZ A;  2Q93 A;  4ZWO A;  3MR1 A;  5D6E A;  1Y1N A;  1B59 A;  2V3Y A;  4PNC A;  2P99 A;  4PV4 A;  4IEC A;  2GU6 A;  3PKA A;  1C22 A;  4MAT A;  3ROR A;  4HXX A;  2Q8K A;  3IG4 A;  3BIP A;  1XGS A;  2HOW A;  4U6Z A;  3BIT A;  3BIQ A;  4FLK A;  2EVC A;  4ZWP A;  2V3X A;  4S01 A;  1C27 A;  1QXZ A;  1C21 A;  1YW9 A;  5CE6 A;  2B3L A;  5FCH A;  2MAT A;  1CHM A;  4FLI A;  4OOK A;  4U6C A;  5FCF A;  1KQ0 A;  2GG7 A;  3IU9 A;  1BN5 A;  1R5H A;  4ZWU A;  2BWW A;  1QZY A;  1WBQ A;  1MAT A;  3PKC A;  4IU6 A;  3CB5 A;  1C23 A;  2Q92 A;  3IU7 A;  2Q94 A;  1QXW A;  2BWY A;  2GGB A;  5JHU A;  2DFI A;  4S2R P;  1WL9 A;  2BWS A;  1O0X A;  4A6V A;  2OAZ A;  4FO8 A;  3TB5 A;  5E5B A;  2BWU A;  1WLR A;  2B3K A;  2EVM A;  1YJ3 A;  1XNZ A;  1WY2 A;  1YW8 A;  2EA4 A;  1BOA A;  3L7G A;  2ADU A;  2GGC A;  3FMR A;  2GG2 A;  4IDY A;  1YVM A;  3S6B A;  1QXY A;  2BH3 A;  4S2T P;  2P9A A;  4JUQ A;  5CDL A;  3CB6 A;  3TAV A;  2BHB A;  2Q95 A;  1XGN A;  4IKR A; 
#chains in the Genus database with same CATH homology
 2GG0 A;  5D6F A;  2BHC A;  1W2M A;  5CIK A;  4FLL A;  4Z7M A;  1PV9 A;  4RZY A;  2GG5 A;  5CDE A;  2BWV A;  1B6A A;  2P98 A;  2B3H A;  2BWT A;  4U76 A;  5JFR A;  3PKB A;  4S00 A;  1KQ9 A;  2EVO A;  2GZ5 A;  2V6C A;  4IKS A;  4U6E A;  4A6W A;  1R58 A;  1YW7 A;  1C24 A;  2EA2 A;  1W7V A;  4U6J A;  4EGE A;  5CNX A;  2GU5 A;  5CDV A;  2BN7 A;  3MAT A;  4FKC A;  2GA2 A;  3MX6 A;  5JI6 A;  1XGO A;  4IF7 A;  3CTZ A;  3D27 A;  1KP0 A;  2BB7 A;  4B28 A;  2BHD A;  2V3Z A;  4KM3 A;  2OKN A;  4FLJ A;  3L24 A;  2GG3 A;  2BHA A;  4U71 A;  3PKD A;  4IKT A;  2ZSG A;  1R5G A;  4U69 A;  4FUK A;  2NQ7 A;  4R60 A;  3PKE A;  3FM3 A;  1JAW A;  2G6P A;  1WKM A;  1WL6 A;  4U70 A;  5CLS A;  2GTX A;  2NQ6 A;  2IW2 A;  3Q6D A;  3IU8 A;  1WN1 A;  4U6W A;  1N51 A;  3FMQ A;  2GU4 A;  4U73 A;  4IKU A;  2BWX A;  4RGZ 1;  3RVA A;  1XGM A;  1M35 A;  2Q96 A;  4FO7 A;  2GG9 A;  4QR8 A;  4U75 A;  4IPA A;  4U1B A;  1A16 A;  4ZNG A;  2GU7 A;  2GG8 A;  4RZZ A;  2Q93 A;  4ZWO A;  3MR1 A;  5D6E A;  1Y1N A;  1B59 A;  2V3Y A;  4PNC A;  2P99 A;  4PV4 A;  4IEC A;  2GU6 A;  3PKA A;  1C22 A;  4MAT A;  3ROR A;  4HXX A;  2Q8K A;  3IG4 A;  3BIP A;  1XGS A;  2HOW A;  4U6Z A;  3BIT A;  3BIQ A;  4FLK A;  2EVC A;  4ZWP A;  2V3X A;  4S01 A;  1C27 A;  1QXZ A;  1C21 A;  1YW9 A;  5CE6 A;  2B3L A;  5FCH A;  2MAT A;  1CHM A;  4FLI A;  4OOK A;  4U6C A;  5FCF A;  1KQ0 A;  2GG7 A;  3IU9 A;  1BN5 A;  1R5H A;  4ZWU A;  2BWW A;  1QZY A;  1WBQ A;  1MAT A;  3PKC A;  4IU6 A;  3CB5 A;  1C23 A;  2Q92 A;  3IU7 A;  2Q94 A;  1QXW A;  2BWY A;  2GGB A;  5JHU A;  2DFI A;  4S2R P;  1WL9 A;  2BWS A;  1O0X A;  4A6V A;  2OAZ A;  4FO8 A;  3TB5 A;  5E5B A;  2BWU A;  1WLR A;  2B3K A;  2EVM A;  1YJ3 A;  1XNZ A;  1WY2 A;  1YW8 A;  2EA4 A;  1BOA A;  3L7G A;  2ADU A;  2GGC A;  3FMR A;  2GG2 A;  4IDY A;  1YVM A;  3S6B A;  1QXY A;  2BH3 A;  4S2T P;  2P9A A;  4JUQ A;  5CDL A;  3CB6 A;  3TAV A;  2BHB A;  2Q95 A;  1XGN A;  4IKR A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...