1C27A

E. coli methionine aminopeptidase:norleucine phosphonate complex
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 85
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c27A00
4U6JA 4U70A 5FCFA 4IDYA 2GG2A 5CIKA 3BITA 3L24A 2EVCA 2Q8KA 4IF7A 4MATA 4OOKA 2B3HA 2BN7A 2P99A 1M35A 4JUQA 5CLSA 5JFRA 2BWYA 2GU5A 4EGEA 1Y1NA 2BWVA 1QXYA 2GGBA 1QXWA 2BHBA 3IU7A 2EA4A 2GTXA 4RZZA 2P9AA 1C21A 2GG9A 4A6WA 1WLRA 2GG7A 4FLIA 2Q94A 4S2TP 2V3ZA 1YW8A 1R58A 4FO7A 4QR8A 4RGZ1 1C22A 3FMRA 1B59A 2HOWA 4RZYA 4KM3A 1A16A 1C24A 2P98A 4U6WA 3MX6A 3CTZA 2MATA 3IU8A 3TAVA 3FM3A 3IU9A 3RVAA 4IKSA 3Q6DA 5CDEA 2GG8A 1WKMA 2ZSGA 1KQ9A 2NQ6A 4IU6A 5CE6A 4IKRA 1YVMA 1QZYA 1KQ0A 2BWUA 4A6VA 2EVOA 5D6EA 4IKTA 4FKCA 3BIQA 1N51A 4IECA 4U75A 1XGOA 2EVMA 4FLJA 3BIPA 2OAZA 4R60A 4S2RP 3PKAA 2OKNA 3D27A 2BWXA 2BHDA 3IG4A 1WL6A 4ZWUA 3S6BA 2ADUA 5CNXA 1WY2A 2BWWA 4FO8A 3PKEA 2GZ5A 5CDLA 2BB7A 2BWTA 3L7GA 4S01A 4U6ZA 1C23A 2Q95A 1R5GA 1XGSA 1KP0A 1MATA 4HXXA 1YJ3A 2V3XA 3TB5A 1BN5A 3MR1A 3FMQA 4PNCA 4U69A 4ZNGA 1C27A 4S00A 4U6EA 4ZWPA 4Z7MA 1XGMA 4U73A 1XNZA 4U76A 1W2MA 3PKDA 4U6CA 2BHCA 2Q92A 1O0XA 2GG5A 2Q96A 2B3LA 4FLKA 1W7VA 4IKUA 1JAWA 1BOAA 2BH3A 1YW9A 4B28A 2GU6A 4FUKA 4ZWOA 2B3KA 1WBQA 5CDVA 5JHUA 1WL9A 1WN1A 2V3YA 3CB6A 3PKBA 2BHAA 5FCHA 2IW2A 4IPAA 3CB5A 2NQ7A 2BWSA 2GU7A 2GA2A 2GG3A 1B6AA 2V6CA 5JI6A 4U1BA 4FLLA 2Q93A 4PV4A 2GGCA 3RORA 1PV9A 1CHMA 1QXZA 1XGNA 3MATA 3PKCA 2G6PA 5E5BA 2EA2A 4U71A 1R5HA 2GU4A 1YW7A 2DFIA 5D6FA 2GG0A
chains in the Genus database with same CATH superfamily
4U6JA 4U70A 5FCFA 4IDYA 2GG2A 5CIKA 3BITA 3L24A 2EVCA 2Q8KA 4IF7A 4MATA 4OOKA 2B3HA 2BN7A 2P99A 1M35A 4JUQA 5CLSA 5JFRA 2BWYA 2GU5A 4EGEA 1Y1NA 2BWVA 1QXYA 2GGBA 1QXWA 2BHBA 3IU7A 2EA4A 2GTXA 4RZZA 2P9AA 1C21A 2GG9A 4A6WA 1WLRA 2GG7A 4FLIA 2Q94A 4S2TP 2V3ZA 1YW8A 1R58A 4FO7A 4QR8A 4RGZ1 1C22A 3FMRA 1B59A 2HOWA 4RZYA 4KM3A 1A16A 1C24A 2P98A 4U6WA 3MX6A 3CTZA 2MATA 3IU8A 3TAVA 3FM3A 3IU9A 3RVAA 4IKSA 3Q6DA 5CDEA 2GG8A 1WKMA 2ZSGA 1KQ9A 2NQ6A 4IU6A 5CE6A 4IKRA 1YVMA 1QZYA 1KQ0A 2BWUA 4A6VA 2EVOA 5D6EA 4IKTA 4FKCA 3BIQA 1N51A 4IECA 4U75A 1XGOA 2EVMA 4FLJA 3BIPA 2OAZA 4R60A 4S2RP 3PKAA 2OKNA 3D27A 2BWXA 2BHDA 3IG4A 1WL6A 4ZWUA 3S6BA 2ADUA 5CNXA 1WY2A 2BWWA 4FO8A 3PKEA 2GZ5A 5CDLA 2BB7A 2BWTA 3L7GA 4S01A 4U6ZA 1C23A 2Q95A 1R5GA 1XGSA 1KP0A 1MATA 4HXXA 1YJ3A 2V3XA 3TB5A 1BN5A 3MR1A 3FMQA 4PNCA 4U69A 4ZNGA 1C27A 4S00A 4U6EA 4ZWPA 4Z7MA 1XGMA 4U73A 1XNZA 4U76A 1W2MA 3PKDA 4U6CA 2BHCA 2Q92A 1O0XA 2GG5A 2Q96A 2B3LA 4FLKA 1W7VA 4IKUA 1JAWA 1BOAA 2BH3A 1YW9A 4B28A 2GU6A 4FUKA 4ZWOA 2B3KA 1WBQA 5CDVA 5JHUA 1WL9A 1WN1A 2V3YA 3CB6A 3PKBA 2BHAA 5FCHA 2IW2A 4IPAA 3CB5A 2NQ7A 2BWSA 2GU7A 2GA2A 2GG3A 1B6AA 2V6CA 5JI6A 4U1BA 4FLLA 2Q93A 4PV4A 2GGCA 3RORA 1PV9A 1CHMA 1QXZA 1XGNA 3MATA 3PKCA 2G6PA 5E5BA 2EA2A 4U71A 1R5HA 2GU4A 1YW7A 2DFIA 5D6FA 2GG0A
chains in the Genus database with same CATH topology
4U6JA 4U70A 5FCFA 4IDYA 2GG2A 5CIKA 3BITA 3L24A 2EVCA 2Q8KA 4IF7A 4MATA 4OOKA 2B3HA 2BN7A 2P99A 1M35A 4JUQA 5CLSA 5JFRA 2BWYA 2GU5A 4EGEA 1Y1NA 2BWVA 1QXYA 2GGBA 1QXWA 2BHBA 3IU7A 2EA4A 2GTXA 4RZZA 2P9AA 1C21A 2GG9A 4A6WA 1WLRA 2GG7A 4FLIA 2Q94A 4S2TP 2V3ZA 1YW8A 1R58A 4FO7A 4QR8A 4RGZ1 1C22A 3FMRA 1B59A 2HOWA 4RZYA 4KM3A 1A16A 1C24A 2P98A 4U6WA 3MX6A 3CTZA 2MATA 3IU8A 3TAVA 3FM3A 3IU9A 3RVAA 4IKSA 3Q6DA 5CDEA 2GG8A 1WKMA 2ZSGA 1KQ9A 2NQ6A 4IU6A 5CE6A 4IKRA 1YVMA 1QZYA 1KQ0A 2BWUA 4A6VA 2EVOA 5D6EA 4IKTA 4FKCA 3BIQA 1N51A 4IECA 4U75A 1XGOA 2EVMA 4FLJA 3BIPA 2OAZA 4R60A 4S2RP 3PKAA 2OKNA 3D27A 2BWXA 2BHDA 3IG4A 1WL6A 4ZWUA 3S6BA 2ADUA 5CNXA 1WY2A 2BWWA 4FO8A 3PKEA 2GZ5A 5CDLA 2BB7A 2BWTA 3L7GA 4S01A 4U6ZA 1C23A 2Q95A 1R5GA 1XGSA 1KP0A 1MATA 4HXXA 1YJ3A 2V3XA 3TB5A 1BN5A 3MR1A 3FMQA 4PNCA 4U69A 4ZNGA 1C27A 4S00A 4U6EA 4ZWPA 4Z7MA 1XGMA 4U73A 1XNZA 4U76A 1W2MA 3PKDA 4U6CA 2BHCA 2Q92A 1O0XA 2GG5A 2Q96A 2B3LA 4FLKA 1W7VA 4IKUA 1JAWA 1BOAA 2BH3A 1YW9A 4B28A 2GU6A 4FUKA 4ZWOA 2B3KA 1WBQA 5CDVA 5JHUA 1WL9A 1WN1A 2V3YA 3CB6A 3PKBA 2BHAA 5FCHA 2IW2A 4IPAA 3CB5A 2NQ7A 2BWSA 2GU7A 2GA2A 2GG3A 1B6AA 2V6CA 5JI6A 4U1BA 4FLLA 2Q93A 4PV4A 2GGCA 3RORA 1PV9A 1CHMA 1QXZA 1XGNA 3MATA 3PKCA 2G6PA 5E5BA 2EA2A 4U71A 1R5HA 2GU4A 1YW7A 2DFIA 5D6FA 2GG0A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6J A;  4U70 A;  5FCF A;  4IDY A;  2GG2 A;  5CIK A;  3BIT A;  3L24 A;  2EVC A;  2Q8K A;  4IF7 A;  4MAT A;  4OOK A;  2B3H A;  2BN7 A;  2P99 A;  1M35 A;  4JUQ A;  5CLS A;  5JFR A;  2BWY A;  2GU5 A;  4EGE A;  1Y1N A;  2BWV A;  1QXY A;  2GGB A;  1QXW A;  2BHB A;  3IU7 A;  2EA4 A;  2GTX A;  4RZZ A;  2P9A A;  1C21 A;  2GG9 A;  4A6W A;  1WLR A;  2GG7 A;  4FLI A;  2Q94 A;  4S2T P;  2V3Z A;  1YW8 A;  1R58 A;  4FO7 A;  4QR8 A;  4RGZ 1;  1C22 A;  3FMR A;  1B59 A;  2HOW A;  4RZY A;  4KM3 A;  1A16 A;  1C24 A;  2P98 A;  4U6W A;  3MX6 A;  3CTZ A;  2MAT A;  3IU8 A;  3TAV A;  3FM3 A;  3IU9 A;  3RVA A;  4IKS A;  3Q6D A;  5CDE A;  2GG8 A;  1WKM A;  2ZSG A;  1KQ9 A;  2NQ6 A;  4IU6 A;  5CE6 A;  4IKR A;  1YVM A;  1QZY A;  1KQ0 A;  2BWU A;  4A6V A;  2EVO A;  5D6E A;  4IKT A;  4FKC A;  3BIQ A;  1N51 A;  4IEC A;  4U75 A;  1XGO A;  2EVM A;  4FLJ A;  3BIP A;  2OAZ A;  4R60 A;  4S2R P;  3PKA A;  2OKN A;  3D27 A;  2BWX A;  2BHD A;  3IG4 A;  1WL6 A;  4ZWU A;  3S6B A;  2ADU A;  5CNX A;  1WY2 A;  2BWW A;  4FO8 A;  3PKE A;  2GZ5 A;  5CDL A;  2BB7 A;  2BWT A;  3L7G A;  4S01 A;  4U6Z A;  1C23 A;  2Q95 A;  1R5G A;  1XGS A;  1KP0 A;  1MAT A;  4HXX A;  1YJ3 A;  2V3X A;  3TB5 A;  1BN5 A;  3MR1 A;  3FMQ A;  4PNC A;  4U69 A;  4ZNG A;  1C27 A;  4S00 A;  4U6E A;  4ZWP A;  4Z7M A;  1XGM A;  4U73 A;  1XNZ A;  4U76 A;  1W2M A;  3PKD A;  4U6C A;  2BHC A;  2Q92 A;  1O0X A;  2GG5 A;  2Q96 A;  2B3L A;  4FLK A;  1W7V A;  4IKU A;  1JAW A;  1BOA A;  2BH3 A;  1YW9 A;  4B28 A;  2GU6 A;  4FUK A;  4ZWO A;  2B3K A;  1WBQ A;  5CDV A;  5JHU A;  1WL9 A;  1WN1 A;  2V3Y A;  3CB6 A;  3PKB A;  2BHA A;  5FCH A;  2IW2 A;  4IPA A;  3CB5 A;  2NQ7 A;  2BWS A;  2GU7 A;  2GA2 A;  2GG3 A;  1B6A A;  2V6C A;  5JI6 A;  4U1B A;  4FLL A;  2Q93 A;  4PV4 A;  2GGC A;  3ROR A;  1PV9 A;  1CHM A;  1QXZ A;  1XGN A;  3MAT A;  3PKC A;  2G6P A;  5E5B A;  2EA2 A;  4U71 A;  1R5H A;  2GU4 A;  1YW7 A;  2DFI A;  5D6F A;  2GG0 A; 
#chains in the Genus database with same CATH topology
 4U6J A;  4U70 A;  5FCF A;  4IDY A;  2GG2 A;  5CIK A;  3BIT A;  3L24 A;  2EVC A;  2Q8K A;  4IF7 A;  4MAT A;  4OOK A;  2B3H A;  2BN7 A;  2P99 A;  1M35 A;  4JUQ A;  5CLS A;  5JFR A;  2BWY A;  2GU5 A;  4EGE A;  1Y1N A;  2BWV A;  1QXY A;  2GGB A;  1QXW A;  2BHB A;  3IU7 A;  2EA4 A;  2GTX A;  4RZZ A;  2P9A A;  1C21 A;  2GG9 A;  4A6W A;  1WLR A;  2GG7 A;  4FLI A;  2Q94 A;  4S2T P;  2V3Z A;  1YW8 A;  1R58 A;  4FO7 A;  4QR8 A;  4RGZ 1;  1C22 A;  3FMR A;  1B59 A;  2HOW A;  4RZY A;  4KM3 A;  1A16 A;  1C24 A;  2P98 A;  4U6W A;  3MX6 A;  3CTZ A;  2MAT A;  3IU8 A;  3TAV A;  3FM3 A;  3IU9 A;  3RVA A;  4IKS A;  3Q6D A;  5CDE A;  2GG8 A;  1WKM A;  2ZSG A;  1KQ9 A;  2NQ6 A;  4IU6 A;  5CE6 A;  4IKR A;  1YVM A;  1QZY A;  1KQ0 A;  2BWU A;  4A6V A;  2EVO A;  5D6E A;  4IKT A;  4FKC A;  3BIQ A;  1N51 A;  4IEC A;  4U75 A;  1XGO A;  2EVM A;  4FLJ A;  3BIP A;  2OAZ A;  4R60 A;  4S2R P;  3PKA A;  2OKN A;  3D27 A;  2BWX A;  2BHD A;  3IG4 A;  1WL6 A;  4ZWU A;  3S6B A;  2ADU A;  5CNX A;  1WY2 A;  2BWW A;  4FO8 A;  3PKE A;  2GZ5 A;  5CDL A;  2BB7 A;  2BWT A;  3L7G A;  4S01 A;  4U6Z A;  1C23 A;  2Q95 A;  1R5G A;  1XGS A;  1KP0 A;  1MAT A;  4HXX A;  1YJ3 A;  2V3X A;  3TB5 A;  1BN5 A;  3MR1 A;  3FMQ A;  4PNC A;  4U69 A;  4ZNG A;  1C27 A;  4S00 A;  4U6E A;  4ZWP A;  4Z7M A;  1XGM A;  4U73 A;  1XNZ A;  4U76 A;  1W2M A;  3PKD A;  4U6C A;  2BHC A;  2Q92 A;  1O0X A;  2GG5 A;  2Q96 A;  2B3L A;  4FLK A;  1W7V A;  4IKU A;  1JAW A;  1BOA A;  2BH3 A;  1YW9 A;  4B28 A;  2GU6 A;  4FUK A;  4ZWO A;  2B3K A;  1WBQ A;  5CDV A;  5JHU A;  1WL9 A;  1WN1 A;  2V3Y A;  3CB6 A;  3PKB A;  2BHA A;  5FCH A;  2IW2 A;  4IPA A;  3CB5 A;  2NQ7 A;  2BWS A;  2GU7 A;  2GA2 A;  2GG3 A;  1B6A A;  2V6C A;  5JI6 A;  4U1B A;  4FLL A;  2Q93 A;  4PV4 A;  2GGC A;  3ROR A;  1PV9 A;  1CHM A;  1QXZ A;  1XGN A;  3MAT A;  3PKC A;  2G6P A;  5E5B A;  2EA2 A;  4U71 A;  1R5H A;  2GU4 A;  1YW7 A;  2DFI A;  5D6F A;  2GG0 A; 
#chains in the Genus database with same CATH homology
 4U6J A;  4U70 A;  5FCF A;  4IDY A;  2GG2 A;  5CIK A;  3BIT A;  3L24 A;  2EVC A;  2Q8K A;  4IF7 A;  4MAT A;  4OOK A;  2B3H A;  2BN7 A;  2P99 A;  1M35 A;  4JUQ A;  5CLS A;  5JFR A;  2BWY A;  2GU5 A;  4EGE A;  1Y1N A;  2BWV A;  1QXY A;  2GGB A;  1QXW A;  2BHB A;  3IU7 A;  2EA4 A;  2GTX A;  4RZZ A;  2P9A A;  1C21 A;  2GG9 A;  4A6W A;  1WLR A;  2GG7 A;  4FLI A;  2Q94 A;  4S2T P;  2V3Z A;  1YW8 A;  1R58 A;  4FO7 A;  4QR8 A;  4RGZ 1;  1C22 A;  3FMR A;  1B59 A;  2HOW A;  4RZY A;  4KM3 A;  1A16 A;  1C24 A;  2P98 A;  4U6W A;  3MX6 A;  3CTZ A;  2MAT A;  3IU8 A;  3TAV A;  3FM3 A;  3IU9 A;  3RVA A;  4IKS A;  3Q6D A;  5CDE A;  2GG8 A;  1WKM A;  2ZSG A;  1KQ9 A;  2NQ6 A;  4IU6 A;  5CE6 A;  4IKR A;  1YVM A;  1QZY A;  1KQ0 A;  2BWU A;  4A6V A;  2EVO A;  5D6E A;  4IKT A;  4FKC A;  3BIQ A;  1N51 A;  4IEC A;  4U75 A;  1XGO A;  2EVM A;  4FLJ A;  3BIP A;  2OAZ A;  4R60 A;  4S2R P;  3PKA A;  2OKN A;  3D27 A;  2BWX A;  2BHD A;  3IG4 A;  1WL6 A;  4ZWU A;  3S6B A;  2ADU A;  5CNX A;  1WY2 A;  2BWW A;  4FO8 A;  3PKE A;  2GZ5 A;  5CDL A;  2BB7 A;  2BWT A;  3L7G A;  4S01 A;  4U6Z A;  1C23 A;  2Q95 A;  1R5G A;  1XGS A;  1KP0 A;  1MAT A;  4HXX A;  1YJ3 A;  2V3X A;  3TB5 A;  1BN5 A;  3MR1 A;  3FMQ A;  4PNC A;  4U69 A;  4ZNG A;  1C27 A;  4S00 A;  4U6E A;  4ZWP A;  4Z7M A;  1XGM A;  4U73 A;  1XNZ A;  4U76 A;  1W2M A;  3PKD A;  4U6C A;  2BHC A;  2Q92 A;  1O0X A;  2GG5 A;  2Q96 A;  2B3L A;  4FLK A;  1W7V A;  4IKU A;  1JAW A;  1BOA A;  2BH3 A;  1YW9 A;  4B28 A;  2GU6 A;  4FUK A;  4ZWO A;  2B3K A;  1WBQ A;  5CDV A;  5JHU A;  1WL9 A;  1WN1 A;  2V3Y A;  3CB6 A;  3PKB A;  2BHA A;  5FCH A;  2IW2 A;  4IPA A;  3CB5 A;  2NQ7 A;  2BWS A;  2GU7 A;  2GA2 A;  2GG3 A;  1B6A A;  2V6C A;  5JI6 A;  4U1B A;  4FLL A;  2Q93 A;  4PV4 A;  2GGC A;  3ROR A;  1PV9 A;  1CHM A;  1QXZ A;  1XGN A;  3MAT A;  3PKC A;  2G6P A;  5E5B A;  2EA2 A;  4U71 A;  1R5H A;  2GU4 A;  1YW7 A;  2DFI A;  5D6F A;  2GG0 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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