3PKEA

M. tuberculosis metap with bengamide analog y10, in ni form
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 88
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkeA01
2GG0A 1XNZA 4ZNGA 2GU5A 2GU6A 3BIQA 5CLSA 2EA4A 2BHDA 3PKBA 5FCFA 1B6AA 4U69A 3IU7A 1R5HA 2BHBA 4IF7A 2GG3A 2OKNA 1QZYA 4U76A 2GZ5A 4ZWUA 4IKRA 5JHUA 1WL6A 2BWYA 2BWVA 3PKEA 2Q92A 2V6CA 3Q6DA 1QXYA 3BIPA 4ZWOA 4S2TP 2GU4A 2GA2A 4QR8A 4KM3A 1W7VA 4RZYA 2ADUA 1Y1NA 2V3XA 4U6JA 1KQ9A 2Q8KA 4JUQA 2EVMA 5E5BA 1WLRA 2V3YA 3MATA 1QXWA 1JAWA 4S2RP 2BHCA 4MATA 1CHMA 3FMQA 4IKUA 4Z7MA 2P99A 1N51A 5D6FA 5CE6A 1WL9A 2EVCA 2GU7A 4FLLA 5CDEA 2V3ZA 1R58A 3FMRA 4IECA 1C23A 2G6PA 3CB6A 3RVAA 2GTXA 4PV4A 4U6WA 1YW8A 4U73A 4RZZA 4U1BA 2GG9A 3L7GA 1MATA 4S01A 3IU8A 1KQ0A 4U6EA 4FLIA 2GG5A 3IU9A 4FLJA 1WY2A 3BITA 4IKTA 4EGEA 3PKCA 5JI6A 1YVMA 3CB5A 2HOWA 4U71A 2GG2A 1W2MA 1XGSA 2OAZA 2BWXA 2B3LA 4ZWPA 3MX6A 4FKCA 2GG8A 4FO8A 2BB7A 4FLKA 5D6EA 1WKMA 5JFRA 2B3KA 4U6CA 2BN7A 3CTZA 4FUKA 2Q96A 2IW2A 1KP0A 4OOKA 1C24A 2BWWA 1C21A 2BHAA 3D27A 4IKSA 4A6VA 1YW9A 2BH3A 1XGMA 2P98A 5CNXA 1XGOA 4IU6A 3RORA 4IPAA 2BWSA 1BOAA 2ZSGA 1B59A 3PKAA 4IDYA 2B3HA 4S00A 2Q93A 2EVOA 5CDLA 2GG7A 4R60A 1C22A 2NQ6A 4RGZ1 3TAVA 5CIKA 1YW7A 5CDVA 4HXXA 1BN5A 3MR1A 4PNCA 1WBQA 1R5GA 2Q94A 2EA2A 4FO7A 3PKDA 1QXZA 1PV9A 1WN1A 3S6BA 2BWUA 1A16A 2DFIA 4A6WA 2Q95A 1O0XA 2GGBA 2NQ7A 3IG4A 4U6ZA 4B28A 1M35A 2MATA 1XGNA 1C27A 5FCHA 2P9AA 3TB5A 3L24A 3FM3A 1YJ3A 4U75A 4U70A 2BWTA 2GGCA
chains in the Genus database with same CATH superfamily
2GG0A 1XNZA 4ZNGA 2GU5A 2GU6A 3BIQA 5CLSA 2EA4A 2BHDA 3PKBA 5FCFA 1B6AA 4U69A 3IU7A 1R5HA 2BHBA 4IF7A 2GG3A 2OKNA 1QZYA 4U76A 2GZ5A 4ZWUA 4IKRA 5JHUA 1WL6A 2BWYA 2BWVA 3PKEA 2Q92A 2V6CA 3Q6DA 1QXYA 3BIPA 4ZWOA 4S2TP 2GU4A 2GA2A 4QR8A 4KM3A 1W7VA 4RZYA 2ADUA 1Y1NA 2V3XA 4U6JA 1KQ9A 2Q8KA 4JUQA 2EVMA 5E5BA 1WLRA 2V3YA 3MATA 1QXWA 1JAWA 4S2RP 2BHCA 4MATA 1CHMA 3FMQA 4IKUA 4Z7MA 2P99A 1N51A 5D6FA 5CE6A 1WL9A 2EVCA 2GU7A 4FLLA 5CDEA 2V3ZA 1R58A 3FMRA 4IECA 1C23A 2G6PA 3CB6A 3RVAA 2GTXA 4PV4A 4U6WA 1YW8A 4U73A 4RZZA 4U1BA 2GG9A 3L7GA 1MATA 4S01A 3IU8A 1KQ0A 4U6EA 4FLIA 2GG5A 3IU9A 4FLJA 1WY2A 3BITA 4IKTA 4EGEA 3PKCA 5JI6A 1YVMA 3CB5A 2HOWA 4U71A 2GG2A 1W2MA 1XGSA 2OAZA 2BWXA 2B3LA 4ZWPA 3MX6A 4FKCA 2GG8A 4FO8A 2BB7A 4FLKA 5D6EA 1WKMA 5JFRA 2B3KA 4U6CA 2BN7A 3CTZA 4FUKA 2Q96A 2IW2A 1KP0A 4OOKA 1C24A 2BWWA 1C21A 2BHAA 3D27A 4IKSA 4A6VA 1YW9A 2BH3A 1XGMA 2P98A 5CNXA 1XGOA 4IU6A 3RORA 4IPAA 2BWSA 1BOAA 2ZSGA 1B59A 3PKAA 4IDYA 2B3HA 4S00A 2Q93A 2EVOA 5CDLA 2GG7A 4R60A 1C22A 2NQ6A 4RGZ1 3TAVA 5CIKA 1YW7A 5CDVA 4HXXA 1BN5A 3MR1A 4PNCA 1WBQA 1R5GA 2Q94A 2EA2A 4FO7A 3PKDA 1QXZA 1PV9A 1WN1A 3S6BA 2BWUA 1A16A 2DFIA 4A6WA 2Q95A 1O0XA 2GGBA 2NQ7A 3IG4A 4U6ZA 4B28A 1M35A 2MATA 1XGNA 1C27A 5FCHA 2P9AA 3TB5A 3L24A 3FM3A 1YJ3A 4U75A 4U70A 2BWTA 2GGCA
chains in the Genus database with same CATH topology
2GG0A 1XNZA 4ZNGA 2GU5A 2GU6A 3BIQA 5CLSA 2EA4A 2BHDA 3PKBA 5FCFA 1B6AA 4U69A 3IU7A 1R5HA 2BHBA 4IF7A 2GG3A 2OKNA 1QZYA 4U76A 2GZ5A 4ZWUA 4IKRA 5JHUA 1WL6A 2BWYA 2BWVA 3PKEA 2Q92A 2V6CA 3Q6DA 1QXYA 3BIPA 4ZWOA 4S2TP 2GU4A 2GA2A 4QR8A 4KM3A 1W7VA 4RZYA 2ADUA 1Y1NA 2V3XA 4U6JA 1KQ9A 2Q8KA 4JUQA 2EVMA 5E5BA 1WLRA 2V3YA 3MATA 1QXWA 1JAWA 4S2RP 2BHCA 4MATA 1CHMA 3FMQA 4IKUA 4Z7MA 2P99A 1N51A 5D6FA 5CE6A 1WL9A 2EVCA 2GU7A 4FLLA 5CDEA 2V3ZA 1R58A 3FMRA 4IECA 1C23A 2G6PA 3CB6A 3RVAA 2GTXA 4PV4A 4U6WA 1YW8A 4U73A 4RZZA 4U1BA 2GG9A 3L7GA 1MATA 4S01A 3IU8A 1KQ0A 4U6EA 4FLIA 2GG5A 3IU9A 4FLJA 1WY2A 3BITA 4IKTA 4EGEA 3PKCA 5JI6A 1YVMA 3CB5A 2HOWA 4U71A 2GG2A 1W2MA 1XGSA 2OAZA 2BWXA 2B3LA 4ZWPA 3MX6A 4FKCA 2GG8A 4FO8A 2BB7A 4FLKA 5D6EA 1WKMA 5JFRA 2B3KA 4U6CA 2BN7A 3CTZA 4FUKA 2Q96A 2IW2A 1KP0A 4OOKA 1C24A 2BWWA 1C21A 2BHAA 3D27A 4IKSA 4A6VA 1YW9A 2BH3A 1XGMA 2P98A 5CNXA 1XGOA 4IU6A 3RORA 4IPAA 2BWSA 1BOAA 2ZSGA 1B59A 3PKAA 4IDYA 2B3HA 4S00A 2Q93A 2EVOA 5CDLA 2GG7A 4R60A 1C22A 2NQ6A 4RGZ1 3TAVA 5CIKA 1YW7A 5CDVA 4HXXA 1BN5A 3MR1A 4PNCA 1WBQA 1R5GA 2Q94A 2EA2A 4FO7A 3PKDA 1QXZA 1PV9A 1WN1A 3S6BA 2BWUA 1A16A 2DFIA 4A6WA 2Q95A 1O0XA 2GGBA 2NQ7A 3IG4A 4U6ZA 4B28A 1M35A 2MATA 1XGNA 1C27A 5FCHA 2P9AA 3TB5A 3L24A 3FM3A 1YJ3A 4U75A 4U70A 2BWTA 2GGCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG0 A;  1XNZ A;  4ZNG A;  2GU5 A;  2GU6 A;  3BIQ A;  5CLS A;  2EA4 A;  2BHD A;  3PKB A;  5FCF A;  1B6A A;  4U69 A;  3IU7 A;  1R5H A;  2BHB A;  4IF7 A;  2GG3 A;  2OKN A;  1QZY A;  4U76 A;  2GZ5 A;  4ZWU A;  4IKR A;  5JHU A;  1WL6 A;  2BWY A;  2BWV A;  3PKE A;  2Q92 A;  2V6C A;  3Q6D A;  1QXY A;  3BIP A;  4ZWO A;  4S2T P;  2GU4 A;  2GA2 A;  4QR8 A;  4KM3 A;  1W7V A;  4RZY A;  2ADU A;  1Y1N A;  2V3X A;  4U6J A;  1KQ9 A;  2Q8K A;  4JUQ A;  2EVM A;  5E5B A;  1WLR A;  2V3Y A;  3MAT A;  1QXW A;  1JAW A;  4S2R P;  2BHC A;  4MAT A;  1CHM A;  3FMQ A;  4IKU A;  4Z7M A;  2P99 A;  1N51 A;  5D6F A;  5CE6 A;  1WL9 A;  2EVC A;  2GU7 A;  4FLL A;  5CDE A;  2V3Z A;  1R58 A;  3FMR A;  4IEC A;  1C23 A;  2G6P A;  3CB6 A;  3RVA A;  2GTX A;  4PV4 A;  4U6W A;  1YW8 A;  4U73 A;  4RZZ A;  4U1B A;  2GG9 A;  3L7G A;  1MAT A;  4S01 A;  3IU8 A;  1KQ0 A;  4U6E A;  4FLI A;  2GG5 A;  3IU9 A;  4FLJ A;  1WY2 A;  3BIT A;  4IKT A;  4EGE A;  3PKC A;  5JI6 A;  1YVM A;  3CB5 A;  2HOW A;  4U71 A;  2GG2 A;  1W2M A;  1XGS A;  2OAZ A;  2BWX A;  2B3L A;  4ZWP A;  3MX6 A;  4FKC A;  2GG8 A;  4FO8 A;  2BB7 A;  4FLK A;  5D6E A;  1WKM A;  5JFR A;  2B3K A;  4U6C A;  2BN7 A;  3CTZ A;  4FUK A;  2Q96 A;  2IW2 A;  1KP0 A;  4OOK A;  1C24 A;  2BWW A;  1C21 A;  2BHA A;  3D27 A;  4IKS A;  4A6V A;  1YW9 A;  2BH3 A;  1XGM A;  2P98 A;  5CNX A;  1XGO A;  4IU6 A;  3ROR A;  4IPA A;  2BWS A;  1BOA A;  2ZSG A;  1B59 A;  3PKA A;  4IDY A;  2B3H A;  4S00 A;  2Q93 A;  2EVO A;  5CDL A;  2GG7 A;  4R60 A;  1C22 A;  2NQ6 A;  4RGZ 1;  3TAV A;  5CIK A;  1YW7 A;  5CDV A;  4HXX A;  1BN5 A;  3MR1 A;  4PNC A;  1WBQ A;  1R5G A;  2Q94 A;  2EA2 A;  4FO7 A;  3PKD A;  1QXZ A;  1PV9 A;  1WN1 A;  3S6B A;  2BWU A;  1A16 A;  2DFI A;  4A6W A;  2Q95 A;  1O0X A;  2GGB A;  2NQ7 A;  3IG4 A;  4U6Z A;  4B28 A;  1M35 A;  2MAT A;  1XGN A;  1C27 A;  5FCH A;  2P9A A;  3TB5 A;  3L24 A;  3FM3 A;  1YJ3 A;  4U75 A;  4U70 A;  2BWT A;  2GGC A; 
#chains in the Genus database with same CATH topology
 2GG0 A;  1XNZ A;  4ZNG A;  2GU5 A;  2GU6 A;  3BIQ A;  5CLS A;  2EA4 A;  2BHD A;  3PKB A;  5FCF A;  1B6A A;  4U69 A;  3IU7 A;  1R5H A;  2BHB A;  4IF7 A;  2GG3 A;  2OKN A;  1QZY A;  4U76 A;  2GZ5 A;  4ZWU A;  4IKR A;  5JHU A;  1WL6 A;  2BWY A;  2BWV A;  3PKE A;  2Q92 A;  2V6C A;  3Q6D A;  1QXY A;  3BIP A;  4ZWO A;  4S2T P;  2GU4 A;  2GA2 A;  4QR8 A;  4KM3 A;  1W7V A;  4RZY A;  2ADU A;  1Y1N A;  2V3X A;  4U6J A;  1KQ9 A;  2Q8K A;  4JUQ A;  2EVM A;  5E5B A;  1WLR A;  2V3Y A;  3MAT A;  1QXW A;  1JAW A;  4S2R P;  2BHC A;  4MAT A;  1CHM A;  3FMQ A;  4IKU A;  4Z7M A;  2P99 A;  1N51 A;  5D6F A;  5CE6 A;  1WL9 A;  2EVC A;  2GU7 A;  4FLL A;  5CDE A;  2V3Z A;  1R58 A;  3FMR A;  4IEC A;  1C23 A;  2G6P A;  3CB6 A;  3RVA A;  2GTX A;  4PV4 A;  4U6W A;  1YW8 A;  4U73 A;  4RZZ A;  4U1B A;  2GG9 A;  3L7G A;  1MAT A;  4S01 A;  3IU8 A;  1KQ0 A;  4U6E A;  4FLI A;  2GG5 A;  3IU9 A;  4FLJ A;  1WY2 A;  3BIT A;  4IKT A;  4EGE A;  3PKC A;  5JI6 A;  1YVM A;  3CB5 A;  2HOW A;  4U71 A;  2GG2 A;  1W2M A;  1XGS A;  2OAZ A;  2BWX A;  2B3L A;  4ZWP A;  3MX6 A;  4FKC A;  2GG8 A;  4FO8 A;  2BB7 A;  4FLK A;  5D6E A;  1WKM A;  5JFR A;  2B3K A;  4U6C A;  2BN7 A;  3CTZ A;  4FUK A;  2Q96 A;  2IW2 A;  1KP0 A;  4OOK A;  1C24 A;  2BWW A;  1C21 A;  2BHA A;  3D27 A;  4IKS A;  4A6V A;  1YW9 A;  2BH3 A;  1XGM A;  2P98 A;  5CNX A;  1XGO A;  4IU6 A;  3ROR A;  4IPA A;  2BWS A;  1BOA A;  2ZSG A;  1B59 A;  3PKA A;  4IDY A;  2B3H A;  4S00 A;  2Q93 A;  2EVO A;  5CDL A;  2GG7 A;  4R60 A;  1C22 A;  2NQ6 A;  4RGZ 1;  3TAV A;  5CIK A;  1YW7 A;  5CDV A;  4HXX A;  1BN5 A;  3MR1 A;  4PNC A;  1WBQ A;  1R5G A;  2Q94 A;  2EA2 A;  4FO7 A;  3PKD A;  1QXZ A;  1PV9 A;  1WN1 A;  3S6B A;  2BWU A;  1A16 A;  2DFI A;  4A6W A;  2Q95 A;  1O0X A;  2GGB A;  2NQ7 A;  3IG4 A;  4U6Z A;  4B28 A;  1M35 A;  2MAT A;  1XGN A;  1C27 A;  5FCH A;  2P9A A;  3TB5 A;  3L24 A;  3FM3 A;  1YJ3 A;  4U75 A;  4U70 A;  2BWT A;  2GGC A; 
#chains in the Genus database with same CATH homology
 2GG0 A;  1XNZ A;  4ZNG A;  2GU5 A;  2GU6 A;  3BIQ A;  5CLS A;  2EA4 A;  2BHD A;  3PKB A;  5FCF A;  1B6A A;  4U69 A;  3IU7 A;  1R5H A;  2BHB A;  4IF7 A;  2GG3 A;  2OKN A;  1QZY A;  4U76 A;  2GZ5 A;  4ZWU A;  4IKR A;  5JHU A;  1WL6 A;  2BWY A;  2BWV A;  3PKE A;  2Q92 A;  2V6C A;  3Q6D A;  1QXY A;  3BIP A;  4ZWO A;  4S2T P;  2GU4 A;  2GA2 A;  4QR8 A;  4KM3 A;  1W7V A;  4RZY A;  2ADU A;  1Y1N A;  2V3X A;  4U6J A;  1KQ9 A;  2Q8K A;  4JUQ A;  2EVM A;  5E5B A;  1WLR A;  2V3Y A;  3MAT A;  1QXW A;  1JAW A;  4S2R P;  2BHC A;  4MAT A;  1CHM A;  3FMQ A;  4IKU A;  4Z7M A;  2P99 A;  1N51 A;  5D6F A;  5CE6 A;  1WL9 A;  2EVC A;  2GU7 A;  4FLL A;  5CDE A;  2V3Z A;  1R58 A;  3FMR A;  4IEC A;  1C23 A;  2G6P A;  3CB6 A;  3RVA A;  2GTX A;  4PV4 A;  4U6W A;  1YW8 A;  4U73 A;  4RZZ A;  4U1B A;  2GG9 A;  3L7G A;  1MAT A;  4S01 A;  3IU8 A;  1KQ0 A;  4U6E A;  4FLI A;  2GG5 A;  3IU9 A;  4FLJ A;  1WY2 A;  3BIT A;  4IKT A;  4EGE A;  3PKC A;  5JI6 A;  1YVM A;  3CB5 A;  2HOW A;  4U71 A;  2GG2 A;  1W2M A;  1XGS A;  2OAZ A;  2BWX A;  2B3L A;  4ZWP A;  3MX6 A;  4FKC A;  2GG8 A;  4FO8 A;  2BB7 A;  4FLK A;  5D6E A;  1WKM A;  5JFR A;  2B3K A;  4U6C A;  2BN7 A;  3CTZ A;  4FUK A;  2Q96 A;  2IW2 A;  1KP0 A;  4OOK A;  1C24 A;  2BWW A;  1C21 A;  2BHA A;  3D27 A;  4IKS A;  4A6V A;  1YW9 A;  2BH3 A;  1XGM A;  2P98 A;  5CNX A;  1XGO A;  4IU6 A;  3ROR A;  4IPA A;  2BWS A;  1BOA A;  2ZSG A;  1B59 A;  3PKA A;  4IDY A;  2B3H A;  4S00 A;  2Q93 A;  2EVO A;  5CDL A;  2GG7 A;  4R60 A;  1C22 A;  2NQ6 A;  4RGZ 1;  3TAV A;  5CIK A;  1YW7 A;  5CDV A;  4HXX A;  1BN5 A;  3MR1 A;  4PNC A;  1WBQ A;  1R5G A;  2Q94 A;  2EA2 A;  4FO7 A;  3PKD A;  1QXZ A;  1PV9 A;  1WN1 A;  3S6B A;  2BWU A;  1A16 A;  2DFI A;  4A6W A;  2Q95 A;  1O0X A;  2GGB A;  2NQ7 A;  3IG4 A;  4U6Z A;  4B28 A;  1M35 A;  2MAT A;  1XGN A;  1C27 A;  5FCH A;  2P9A A;  3TB5 A;  3L24 A;  3FM3 A;  1YJ3 A;  4U75 A;  4U70 A;  2BWT A;  2GGC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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