3PKEA

M. tuberculosis metap with bengamide analog y10, in ni form
Total Genus 88
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 88
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkeA01
2GZ5A 2Q92A 2BWTA 2B3HA 2NQ7A 4ZWOA 1KQ9A 3BIPA 1BOAA 4B28A 2OAZA 4U69A 2BH3A 2MATA 1M35A 3RVAA 1PV9A 1JAWA 2BB7A 4FO8A 4S01A 2EA4A 2GG9A 4U6JA 5JFRA 3CB6A 3PKEA 4U6ZA 4U71A 5JI6A 4ZNGA 2EVOA 2G6PA 1W2MA 1C22A 1QXZA 4FLKA 2P98A 2V3XA 1WBQA 1YW8A 2GA2A 2V6CA 4S00A 2BHBA 2GU5A 1Y1NA 4PV4A 1YVMA 2B3KA 1MATA 3Q6DA 1WL6A 5CDLA 1WY2A 4MATA 1R5HA 4FLIA 4ZWPA 2GG2A 2BWUA 2BHDA 3PKAA 1R5GA 1XGNA 2OKNA 1WLRA 1W7VA 1C21A 2ADUA 3S6BA 4R60A 1B59A 1XGOA 4IU6A 1XNZA 1B6AA 4FUKA 2GG7A 5E5BA 3PKCA 2NQ6A 5CDEA 5FCHA 4IKUA 2BHCA 5CE6A 3FMRA 3CTZA 2BWYA 2BWVA 3MATA 3BIQA 2GG8A 4QR8A 4U76A 2GU4A 1QXYA 2Q96A 2ZSGA 5D6FA 4FLLA 3PKBA 1WN1A 2DFIA 4IKRA 4JUQA 1YW7A 5CDVA 4EGEA 3D27A 4IKSA 5CNXA 5JHUA 5D6EA 1A16A 2BWSA 4Z7MA 2Q95A 4FO7A 1O0XA 2EA2A 3IG4A 4RGZ1 2BHAA 4RZZA 3FMQA 2GGBA 2GTXA 1CHMA 4RZYA 2GG0A 3IU8A 2V3YA 3PKDA 4HXXA 3FM3A 4ZWUA 4KM3A 4FKCA 1C27A 2IW2A 1KP0A 3BITA 1YJ3A 3MR1A 1KQ0A 1N51A 4IDYA 2BN7A 1XGSA 2P99A 4IECA 4S2RP 4S2TP 5CIKA 2EVCA 3CB5A 3MX6A 2GGCA 2Q94A 4A6VA 2GU6A 2BWWA 1QZYA 2Q93A 2V3ZA 4IF7A 2Q8KA 4A6WA 3TAVA 1C24A 4IPAA 3IU7A 2GG3A 4U6CA 5CLSA 2GG5A 4FLJA 1R58A 3IU9A 4OOKA 4PNCA 4U70A 2BWXA 1QXWA 2EVMA 1WKMA 1C23A 1WL9A 3TB5A 3RORA 2P9AA 3L24A 1BN5A 1XGMA 3L7GA 4U6WA 4IKTA 4U75A 4U73A 4U6EA 1YW9A 5FCFA 2GU7A 2HOWA 2B3LA 4U1BA
chains in the Genus database with same CATH superfamily
2GZ5A 2Q92A 2BWTA 2B3HA 2NQ7A 4ZWOA 1KQ9A 3BIPA 1BOAA 4B28A 2OAZA 4U69A 2BH3A 2MATA 1M35A 3RVAA 1PV9A 1JAWA 2BB7A 4FO8A 4S01A 2EA4A 2GG9A 4U6JA 5JFRA 3CB6A 3PKEA 4U6ZA 4U71A 5JI6A 4ZNGA 2EVOA 2G6PA 1W2MA 1C22A 1QXZA 4FLKA 2P98A 2V3XA 1WBQA 1YW8A 2GA2A 2V6CA 4S00A 2BHBA 2GU5A 1Y1NA 4PV4A 1YVMA 2B3KA 1MATA 3Q6DA 1WL6A 5CDLA 1WY2A 4MATA 1R5HA 4FLIA 4ZWPA 2GG2A 2BWUA 2BHDA 3PKAA 1R5GA 1XGNA 2OKNA 1WLRA 1W7VA 1C21A 2ADUA 3S6BA 4R60A 1B59A 1XGOA 4IU6A 1XNZA 1B6AA 4FUKA 2GG7A 5E5BA 3PKCA 2NQ6A 5CDEA 5FCHA 4IKUA 2BHCA 5CE6A 3FMRA 3CTZA 2BWYA 2BWVA 3MATA 3BIQA 2GG8A 4QR8A 4U76A 2GU4A 1QXYA 2Q96A 2ZSGA 5D6FA 4FLLA 3PKBA 1WN1A 2DFIA 4IKRA 4JUQA 1YW7A 5CDVA 4EGEA 3D27A 4IKSA 5CNXA 5JHUA 5D6EA 1A16A 2BWSA 4Z7MA 2Q95A 4FO7A 1O0XA 2EA2A 3IG4A 4RGZ1 2BHAA 4RZZA 3FMQA 2GGBA 2GTXA 1CHMA 4RZYA 2GG0A 3IU8A 2V3YA 3PKDA 4HXXA 3FM3A 4ZWUA 4KM3A 4FKCA 1C27A 2IW2A 1KP0A 3BITA 1YJ3A 3MR1A 1KQ0A 1N51A 4IDYA 2BN7A 1XGSA 2P99A 4IECA 4S2RP 4S2TP 5CIKA 2EVCA 3CB5A 3MX6A 2GGCA 2Q94A 4A6VA 2GU6A 2BWWA 1QZYA 2Q93A 2V3ZA 4IF7A 2Q8KA 4A6WA 3TAVA 1C24A 4IPAA 3IU7A 2GG3A 4U6CA 5CLSA 2GG5A 4FLJA 1R58A 3IU9A 4OOKA 4PNCA 4U70A 2BWXA 1QXWA 2EVMA 1WKMA 1C23A 1WL9A 3TB5A 3RORA 2P9AA 3L24A 1BN5A 1XGMA 3L7GA 4U6WA 4IKTA 4U75A 4U73A 4U6EA 1YW9A 5FCFA 2GU7A 2HOWA 2B3LA 4U1BA
chains in the Genus database with same CATH topology
2GZ5A 2Q92A 2BWTA 2B3HA 2NQ7A 4ZWOA 1KQ9A 3BIPA 1BOAA 4B28A 2OAZA 4U69A 2BH3A 2MATA 1M35A 3RVAA 1PV9A 1JAWA 2BB7A 4FO8A 4S01A 2EA4A 2GG9A 4U6JA 5JFRA 3CB6A 3PKEA 4U6ZA 4U71A 5JI6A 4ZNGA 2EVOA 2G6PA 1W2MA 1C22A 1QXZA 4FLKA 2P98A 2V3XA 1WBQA 1YW8A 2GA2A 2V6CA 4S00A 2BHBA 2GU5A 1Y1NA 4PV4A 1YVMA 2B3KA 1MATA 3Q6DA 1WL6A 5CDLA 1WY2A 4MATA 1R5HA 4FLIA 4ZWPA 2GG2A 2BWUA 2BHDA 3PKAA 1R5GA 1XGNA 2OKNA 1WLRA 1W7VA 1C21A 2ADUA 3S6BA 4R60A 1B59A 1XGOA 4IU6A 1XNZA 1B6AA 4FUKA 2GG7A 5E5BA 3PKCA 2NQ6A 5CDEA 5FCHA 4IKUA 2BHCA 5CE6A 3FMRA 3CTZA 2BWYA 2BWVA 3MATA 3BIQA 2GG8A 4QR8A 4U76A 2GU4A 1QXYA 2Q96A 2ZSGA 5D6FA 4FLLA 3PKBA 1WN1A 2DFIA 4IKRA 4JUQA 1YW7A 5CDVA 4EGEA 3D27A 4IKSA 5CNXA 5JHUA 5D6EA 1A16A 2BWSA 4Z7MA 2Q95A 4FO7A 1O0XA 2EA2A 3IG4A 4RGZ1 2BHAA 4RZZA 3FMQA 2GGBA 2GTXA 1CHMA 4RZYA 2GG0A 3IU8A 2V3YA 3PKDA 4HXXA 3FM3A 4ZWUA 4KM3A 4FKCA 1C27A 2IW2A 1KP0A 3BITA 1YJ3A 3MR1A 1KQ0A 1N51A 4IDYA 2BN7A 1XGSA 2P99A 4IECA 4S2RP 4S2TP 5CIKA 2EVCA 3CB5A 3MX6A 2GGCA 2Q94A 4A6VA 2GU6A 2BWWA 1QZYA 2Q93A 2V3ZA 4IF7A 2Q8KA 4A6WA 3TAVA 1C24A 4IPAA 3IU7A 2GG3A 4U6CA 5CLSA 2GG5A 4FLJA 1R58A 3IU9A 4OOKA 4PNCA 4U70A 2BWXA 1QXWA 2EVMA 1WKMA 1C23A 1WL9A 3TB5A 3RORA 2P9AA 3L24A 1BN5A 1XGMA 3L7GA 4U6WA 4IKTA 4U75A 4U73A 4U6EA 1YW9A 5FCFA 2GU7A 2HOWA 2B3LA 4U1BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GZ5 A;  2Q92 A;  2BWT A;  2B3H A;  2NQ7 A;  4ZWO A;  1KQ9 A;  3BIP A;  1BOA A;  4B28 A;  2OAZ A;  4U69 A;  2BH3 A;  2MAT A;  1M35 A;  3RVA A;  1PV9 A;  1JAW A;  2BB7 A;  4FO8 A;  4S01 A;  2EA4 A;  2GG9 A;  4U6J A;  5JFR A;  3CB6 A;  3PKE A;  4U6Z A;  4U71 A;  5JI6 A;  4ZNG A;  2EVO A;  2G6P A;  1W2M A;  1C22 A;  1QXZ A;  4FLK A;  2P98 A;  2V3X A;  1WBQ A;  1YW8 A;  2GA2 A;  2V6C A;  4S00 A;  2BHB A;  2GU5 A;  1Y1N A;  4PV4 A;  1YVM A;  2B3K A;  1MAT A;  3Q6D A;  1WL6 A;  5CDL A;  1WY2 A;  4MAT A;  1R5H A;  4FLI A;  4ZWP A;  2GG2 A;  2BWU A;  2BHD A;  3PKA A;  1R5G A;  1XGN A;  2OKN A;  1WLR A;  1W7V A;  1C21 A;  2ADU A;  3S6B A;  4R60 A;  1B59 A;  1XGO A;  4IU6 A;  1XNZ A;  1B6A A;  4FUK A;  2GG7 A;  5E5B A;  3PKC A;  2NQ6 A;  5CDE A;  5FCH A;  4IKU A;  2BHC A;  5CE6 A;  3FMR A;  3CTZ A;  2BWY A;  2BWV A;  3MAT A;  3BIQ A;  2GG8 A;  4QR8 A;  4U76 A;  2GU4 A;  1QXY A;  2Q96 A;  2ZSG A;  5D6F A;  4FLL A;  3PKB A;  1WN1 A;  2DFI A;  4IKR A;  4JUQ A;  1YW7 A;  5CDV A;  4EGE A;  3D27 A;  4IKS A;  5CNX A;  5JHU A;  5D6E A;  1A16 A;  2BWS A;  4Z7M A;  2Q95 A;  4FO7 A;  1O0X A;  2EA2 A;  3IG4 A;  4RGZ 1;  2BHA A;  4RZZ A;  3FMQ A;  2GGB A;  2GTX A;  1CHM A;  4RZY A;  2GG0 A;  3IU8 A;  2V3Y A;  3PKD A;  4HXX A;  3FM3 A;  4ZWU A;  4KM3 A;  4FKC A;  1C27 A;  2IW2 A;  1KP0 A;  3BIT A;  1YJ3 A;  3MR1 A;  1KQ0 A;  1N51 A;  4IDY A;  2BN7 A;  1XGS A;  2P99 A;  4IEC A;  4S2R P;  4S2T P;  5CIK A;  2EVC A;  3CB5 A;  3MX6 A;  2GGC A;  2Q94 A;  4A6V A;  2GU6 A;  2BWW A;  1QZY A;  2Q93 A;  2V3Z A;  4IF7 A;  2Q8K A;  4A6W A;  3TAV A;  1C24 A;  4IPA A;  3IU7 A;  2GG3 A;  4U6C A;  5CLS A;  2GG5 A;  4FLJ A;  1R58 A;  3IU9 A;  4OOK A;  4PNC A;  4U70 A;  2BWX A;  1QXW A;  2EVM A;  1WKM A;  1C23 A;  1WL9 A;  3TB5 A;  3ROR A;  2P9A A;  3L24 A;  1BN5 A;  1XGM A;  3L7G A;  4U6W A;  4IKT A;  4U75 A;  4U73 A;  4U6E A;  1YW9 A;  5FCF A;  2GU7 A;  2HOW A;  2B3L A;  4U1B A; 
#chains in the Genus database with same CATH topology
 2GZ5 A;  2Q92 A;  2BWT A;  2B3H A;  2NQ7 A;  4ZWO A;  1KQ9 A;  3BIP A;  1BOA A;  4B28 A;  2OAZ A;  4U69 A;  2BH3 A;  2MAT A;  1M35 A;  3RVA A;  1PV9 A;  1JAW A;  2BB7 A;  4FO8 A;  4S01 A;  2EA4 A;  2GG9 A;  4U6J A;  5JFR A;  3CB6 A;  3PKE A;  4U6Z A;  4U71 A;  5JI6 A;  4ZNG A;  2EVO A;  2G6P A;  1W2M A;  1C22 A;  1QXZ A;  4FLK A;  2P98 A;  2V3X A;  1WBQ A;  1YW8 A;  2GA2 A;  2V6C A;  4S00 A;  2BHB A;  2GU5 A;  1Y1N A;  4PV4 A;  1YVM A;  2B3K A;  1MAT A;  3Q6D A;  1WL6 A;  5CDL A;  1WY2 A;  4MAT A;  1R5H A;  4FLI A;  4ZWP A;  2GG2 A;  2BWU A;  2BHD A;  3PKA A;  1R5G A;  1XGN A;  2OKN A;  1WLR A;  1W7V A;  1C21 A;  2ADU A;  3S6B A;  4R60 A;  1B59 A;  1XGO A;  4IU6 A;  1XNZ A;  1B6A A;  4FUK A;  2GG7 A;  5E5B A;  3PKC A;  2NQ6 A;  5CDE A;  5FCH A;  4IKU A;  2BHC A;  5CE6 A;  3FMR A;  3CTZ A;  2BWY A;  2BWV A;  3MAT A;  3BIQ A;  2GG8 A;  4QR8 A;  4U76 A;  2GU4 A;  1QXY A;  2Q96 A;  2ZSG A;  5D6F A;  4FLL A;  3PKB A;  1WN1 A;  2DFI A;  4IKR A;  4JUQ A;  1YW7 A;  5CDV A;  4EGE A;  3D27 A;  4IKS A;  5CNX A;  5JHU A;  5D6E A;  1A16 A;  2BWS A;  4Z7M A;  2Q95 A;  4FO7 A;  1O0X A;  2EA2 A;  3IG4 A;  4RGZ 1;  2BHA A;  4RZZ A;  3FMQ A;  2GGB A;  2GTX A;  1CHM A;  4RZY A;  2GG0 A;  3IU8 A;  2V3Y A;  3PKD A;  4HXX A;  3FM3 A;  4ZWU A;  4KM3 A;  4FKC A;  1C27 A;  2IW2 A;  1KP0 A;  3BIT A;  1YJ3 A;  3MR1 A;  1KQ0 A;  1N51 A;  4IDY A;  2BN7 A;  1XGS A;  2P99 A;  4IEC A;  4S2R P;  4S2T P;  5CIK A;  2EVC A;  3CB5 A;  3MX6 A;  2GGC A;  2Q94 A;  4A6V A;  2GU6 A;  2BWW A;  1QZY A;  2Q93 A;  2V3Z A;  4IF7 A;  2Q8K A;  4A6W A;  3TAV A;  1C24 A;  4IPA A;  3IU7 A;  2GG3 A;  4U6C A;  5CLS A;  2GG5 A;  4FLJ A;  1R58 A;  3IU9 A;  4OOK A;  4PNC A;  4U70 A;  2BWX A;  1QXW A;  2EVM A;  1WKM A;  1C23 A;  1WL9 A;  3TB5 A;  3ROR A;  2P9A A;  3L24 A;  1BN5 A;  1XGM A;  3L7G A;  4U6W A;  4IKT A;  4U75 A;  4U73 A;  4U6E A;  1YW9 A;  5FCF A;  2GU7 A;  2HOW A;  2B3L A;  4U1B A; 
#chains in the Genus database with same CATH homology
 2GZ5 A;  2Q92 A;  2BWT A;  2B3H A;  2NQ7 A;  4ZWO A;  1KQ9 A;  3BIP A;  1BOA A;  4B28 A;  2OAZ A;  4U69 A;  2BH3 A;  2MAT A;  1M35 A;  3RVA A;  1PV9 A;  1JAW A;  2BB7 A;  4FO8 A;  4S01 A;  2EA4 A;  2GG9 A;  4U6J A;  5JFR A;  3CB6 A;  3PKE A;  4U6Z A;  4U71 A;  5JI6 A;  4ZNG A;  2EVO A;  2G6P A;  1W2M A;  1C22 A;  1QXZ A;  4FLK A;  2P98 A;  2V3X A;  1WBQ A;  1YW8 A;  2GA2 A;  2V6C A;  4S00 A;  2BHB A;  2GU5 A;  1Y1N A;  4PV4 A;  1YVM A;  2B3K A;  1MAT A;  3Q6D A;  1WL6 A;  5CDL A;  1WY2 A;  4MAT A;  1R5H A;  4FLI A;  4ZWP A;  2GG2 A;  2BWU A;  2BHD A;  3PKA A;  1R5G A;  1XGN A;  2OKN A;  1WLR A;  1W7V A;  1C21 A;  2ADU A;  3S6B A;  4R60 A;  1B59 A;  1XGO A;  4IU6 A;  1XNZ A;  1B6A A;  4FUK A;  2GG7 A;  5E5B A;  3PKC A;  2NQ6 A;  5CDE A;  5FCH A;  4IKU A;  2BHC A;  5CE6 A;  3FMR A;  3CTZ A;  2BWY A;  2BWV A;  3MAT A;  3BIQ A;  2GG8 A;  4QR8 A;  4U76 A;  2GU4 A;  1QXY A;  2Q96 A;  2ZSG A;  5D6F A;  4FLL A;  3PKB A;  1WN1 A;  2DFI A;  4IKR A;  4JUQ A;  1YW7 A;  5CDV A;  4EGE A;  3D27 A;  4IKS A;  5CNX A;  5JHU A;  5D6E A;  1A16 A;  2BWS A;  4Z7M A;  2Q95 A;  4FO7 A;  1O0X A;  2EA2 A;  3IG4 A;  4RGZ 1;  2BHA A;  4RZZ A;  3FMQ A;  2GGB A;  2GTX A;  1CHM A;  4RZY A;  2GG0 A;  3IU8 A;  2V3Y A;  3PKD A;  4HXX A;  3FM3 A;  4ZWU A;  4KM3 A;  4FKC A;  1C27 A;  2IW2 A;  1KP0 A;  3BIT A;  1YJ3 A;  3MR1 A;  1KQ0 A;  1N51 A;  4IDY A;  2BN7 A;  1XGS A;  2P99 A;  4IEC A;  4S2R P;  4S2T P;  5CIK A;  2EVC A;  3CB5 A;  3MX6 A;  2GGC A;  2Q94 A;  4A6V A;  2GU6 A;  2BWW A;  1QZY A;  2Q93 A;  2V3Z A;  4IF7 A;  2Q8K A;  4A6W A;  3TAV A;  1C24 A;  4IPA A;  3IU7 A;  2GG3 A;  4U6C A;  5CLS A;  2GG5 A;  4FLJ A;  1R58 A;  3IU9 A;  4OOK A;  4PNC A;  4U70 A;  2BWX A;  1QXW A;  2EVM A;  1WKM A;  1C23 A;  1WL9 A;  3TB5 A;  3ROR A;  2P9A A;  3L24 A;  1BN5 A;  1XGM A;  3L7G A;  4U6W A;  4IKT A;  4U75 A;  4U73 A;  4U6E A;  1YW9 A;  5FCF A;  2GU7 A;  2HOW A;  2B3L A;  4U1B A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...