3PKEA

M. tuberculosis metap with bengamide analog y10, in ni form
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 88
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkeA01
1C24A 2GG0A 4U6CA 5D6EA 2IW2A 2GU6A 1YW8A 5CIKA 5FCFA 4ZWUA 1M35A 1C21A 4U73A 1QXYA 5CDVA 4FO7A 4HXXA 1WBQA 2ADUA 4RZYA 1WL9A 2GU4A 2Q92A 2GG2A 3FMQA 3L24A 3PKDA 2BWXA 2OKNA 1WL6A 4IPAA 1BOAA 2OAZA 3MR1A 3CB6A 1QZYA 2BHAA 4S2TP 2BHBA 4S01A 2BB7A 1W7VA 1QXWA 1XNZA 2V3XA 3FMRA 2G6PA 1KQ9A 1WKMA 3D27A 1JAWA 2BWTA 2GU5A 2BWVA 2V6CA 4U76A 1B6AA 4KM3A 4Z7MA 2P9AA 4ZNGA 4R60A 4U6ZA 3TB5A 3RVAA 2MATA 4MATA 5JFRA 2BHDA 3BIPA 4FLJA 5FCHA 2Q8KA 4FO8A 4OOKA 3TAVA 1WY2A 2HOWA 2Q94A 4S2RP 2EVMA 5D6FA 2NQ7A 4QR8A 5CLSA 4RZZA 4U75A 4FKCA 2BWSA 2GG8A 3IU9A 2BN7A 2GZ5A 5E5BA 1XGSA 2ZSGA 4IDYA 4FLIA 3MATA 2BH3A 4PNCA 1B59A 5CDEA 1WN1A 1CHMA 2GGCA 2GU7A 2V3YA 3PKEA 4U6WA 3S6BA 2EA2A 3IU7A 4A6VA 1R58A 2B3HA 2Q96A 2EVOA 1MATA 2GG5A 1KQ0A 1XGMA 2GA2A 4IF7A 4IU6A 4IKRA 3Q6DA 4FLLA 2DFIA 4A6WA 1QXZA 3IU8A 3PKBA 1BN5A 1R5GA 3L7GA 5JHUA 1WLRA 2BWUA 3CTZA 4FUKA 1PV9A 2EVCA 5CDLA 3FM3A 2GG9A 2GGBA 1YW7A 4U71A 3RORA 3BIQA 2EA4A 3PKCA 1C22A 4S00A 4IKUA 2Q93A 1YJ3A 4EGEA 4U70A 1O0XA 1KP0A 2B3LA 2BWWA 2P98A 4ZWPA 3BITA 4IKTA 4B28A 4U69A 2BWYA 3CB5A 4U6JA 5CE6A 3MX6A 2GG3A 1XGOA 4ZWOA 2GG7A 4U6EA 2V3ZA 2BHCA 1W2MA 1C23A 3IG4A 4IECA 4IKSA 3PKAA 4RGZ1 2B3KA 1A16A 2P99A 5CNXA 2NQ6A 4PV4A 4FLKA 1N51A 1R5HA 2Q95A 4U1BA 1YW9A 1C27A 1YVMA 1Y1NA 1XGNA 5JI6A 2GTXA 4JUQA
chains in the Genus database with same CATH superfamily
1C24A 2GG0A 4U6CA 5D6EA 2IW2A 2GU6A 1YW8A 5CIKA 5FCFA 4ZWUA 1M35A 1C21A 4U73A 1QXYA 5CDVA 4FO7A 4HXXA 1WBQA 2ADUA 4RZYA 1WL9A 2GU4A 2Q92A 2GG2A 3FMQA 3L24A 3PKDA 2BWXA 2OKNA 1WL6A 4IPAA 1BOAA 2OAZA 3MR1A 3CB6A 1QZYA 2BHAA 4S2TP 2BHBA 4S01A 2BB7A 1W7VA 1QXWA 1XNZA 2V3XA 3FMRA 2G6PA 1KQ9A 1WKMA 3D27A 1JAWA 2BWTA 2GU5A 2BWVA 2V6CA 4U76A 1B6AA 4KM3A 4Z7MA 2P9AA 4ZNGA 4R60A 4U6ZA 3TB5A 3RVAA 2MATA 4MATA 5JFRA 2BHDA 3BIPA 4FLJA 5FCHA 2Q8KA 4FO8A 4OOKA 3TAVA 1WY2A 2HOWA 2Q94A 4S2RP 2EVMA 5D6FA 2NQ7A 4QR8A 5CLSA 4RZZA 4U75A 4FKCA 2BWSA 2GG8A 3IU9A 2BN7A 2GZ5A 5E5BA 1XGSA 2ZSGA 4IDYA 4FLIA 3MATA 2BH3A 4PNCA 1B59A 5CDEA 1WN1A 1CHMA 2GGCA 2GU7A 2V3YA 3PKEA 4U6WA 3S6BA 2EA2A 3IU7A 4A6VA 1R58A 2B3HA 2Q96A 2EVOA 1MATA 2GG5A 1KQ0A 1XGMA 2GA2A 4IF7A 4IU6A 4IKRA 3Q6DA 4FLLA 2DFIA 4A6WA 1QXZA 3IU8A 3PKBA 1BN5A 1R5GA 3L7GA 5JHUA 1WLRA 2BWUA 3CTZA 4FUKA 1PV9A 2EVCA 5CDLA 3FM3A 2GG9A 2GGBA 1YW7A 4U71A 3RORA 3BIQA 2EA4A 3PKCA 1C22A 4S00A 4IKUA 2Q93A 1YJ3A 4EGEA 4U70A 1O0XA 1KP0A 2B3LA 2BWWA 2P98A 4ZWPA 3BITA 4IKTA 4B28A 4U69A 2BWYA 3CB5A 4U6JA 5CE6A 3MX6A 2GG3A 1XGOA 4ZWOA 2GG7A 4U6EA 2V3ZA 2BHCA 1W2MA 1C23A 3IG4A 4IECA 4IKSA 3PKAA 4RGZ1 2B3KA 1A16A 2P99A 5CNXA 2NQ6A 4PV4A 4FLKA 1N51A 1R5HA 2Q95A 4U1BA 1YW9A 1C27A 1YVMA 1Y1NA 1XGNA 5JI6A 2GTXA 4JUQA
chains in the Genus database with same CATH topology
1C24A 2GG0A 4U6CA 5D6EA 2IW2A 2GU6A 1YW8A 5CIKA 5FCFA 4ZWUA 1M35A 1C21A 4U73A 1QXYA 5CDVA 4FO7A 4HXXA 1WBQA 2ADUA 4RZYA 1WL9A 2GU4A 2Q92A 2GG2A 3FMQA 3L24A 3PKDA 2BWXA 2OKNA 1WL6A 4IPAA 1BOAA 2OAZA 3MR1A 3CB6A 1QZYA 2BHAA 4S2TP 2BHBA 4S01A 2BB7A 1W7VA 1QXWA 1XNZA 2V3XA 3FMRA 2G6PA 1KQ9A 1WKMA 3D27A 1JAWA 2BWTA 2GU5A 2BWVA 2V6CA 4U76A 1B6AA 4KM3A 4Z7MA 2P9AA 4ZNGA 4R60A 4U6ZA 3TB5A 3RVAA 2MATA 4MATA 5JFRA 2BHDA 3BIPA 4FLJA 5FCHA 2Q8KA 4FO8A 4OOKA 3TAVA 1WY2A 2HOWA 2Q94A 4S2RP 2EVMA 5D6FA 2NQ7A 4QR8A 5CLSA 4RZZA 4U75A 4FKCA 2BWSA 2GG8A 3IU9A 2BN7A 2GZ5A 5E5BA 1XGSA 2ZSGA 4IDYA 4FLIA 3MATA 2BH3A 4PNCA 1B59A 5CDEA 1WN1A 1CHMA 2GGCA 2GU7A 2V3YA 3PKEA 4U6WA 3S6BA 2EA2A 3IU7A 4A6VA 1R58A 2B3HA 2Q96A 2EVOA 1MATA 2GG5A 1KQ0A 1XGMA 2GA2A 4IF7A 4IU6A 4IKRA 3Q6DA 4FLLA 2DFIA 4A6WA 1QXZA 3IU8A 3PKBA 1BN5A 1R5GA 3L7GA 5JHUA 1WLRA 2BWUA 3CTZA 4FUKA 1PV9A 2EVCA 5CDLA 3FM3A 2GG9A 2GGBA 1YW7A 4U71A 3RORA 3BIQA 2EA4A 3PKCA 1C22A 4S00A 4IKUA 2Q93A 1YJ3A 4EGEA 4U70A 1O0XA 1KP0A 2B3LA 2BWWA 2P98A 4ZWPA 3BITA 4IKTA 4B28A 4U69A 2BWYA 3CB5A 4U6JA 5CE6A 3MX6A 2GG3A 1XGOA 4ZWOA 2GG7A 4U6EA 2V3ZA 2BHCA 1W2MA 1C23A 3IG4A 4IECA 4IKSA 3PKAA 4RGZ1 2B3KA 1A16A 2P99A 5CNXA 2NQ6A 4PV4A 4FLKA 1N51A 1R5HA 2Q95A 4U1BA 1YW9A 1C27A 1YVMA 1Y1NA 1XGNA 5JI6A 2GTXA 4JUQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C24 A;  2GG0 A;  4U6C A;  5D6E A;  2IW2 A;  2GU6 A;  1YW8 A;  5CIK A;  5FCF A;  4ZWU A;  1M35 A;  1C21 A;  4U73 A;  1QXY A;  5CDV A;  4FO7 A;  4HXX A;  1WBQ A;  2ADU A;  4RZY A;  1WL9 A;  2GU4 A;  2Q92 A;  2GG2 A;  3FMQ A;  3L24 A;  3PKD A;  2BWX A;  2OKN A;  1WL6 A;  4IPA A;  1BOA A;  2OAZ A;  3MR1 A;  3CB6 A;  1QZY A;  2BHA A;  4S2T P;  2BHB A;  4S01 A;  2BB7 A;  1W7V A;  1QXW A;  1XNZ A;  2V3X A;  3FMR A;  2G6P A;  1KQ9 A;  1WKM A;  3D27 A;  1JAW A;  2BWT A;  2GU5 A;  2BWV A;  2V6C A;  4U76 A;  1B6A A;  4KM3 A;  4Z7M A;  2P9A A;  4ZNG A;  4R60 A;  4U6Z A;  3TB5 A;  3RVA A;  2MAT A;  4MAT A;  5JFR A;  2BHD A;  3BIP A;  4FLJ A;  5FCH A;  2Q8K A;  4FO8 A;  4OOK A;  3TAV A;  1WY2 A;  2HOW A;  2Q94 A;  4S2R P;  2EVM A;  5D6F A;  2NQ7 A;  4QR8 A;  5CLS A;  4RZZ A;  4U75 A;  4FKC A;  2BWS A;  2GG8 A;  3IU9 A;  2BN7 A;  2GZ5 A;  5E5B A;  1XGS A;  2ZSG A;  4IDY A;  4FLI A;  3MAT A;  2BH3 A;  4PNC A;  1B59 A;  5CDE A;  1WN1 A;  1CHM A;  2GGC A;  2GU7 A;  2V3Y A;  3PKE A;  4U6W A;  3S6B A;  2EA2 A;  3IU7 A;  4A6V A;  1R58 A;  2B3H A;  2Q96 A;  2EVO A;  1MAT A;  2GG5 A;  1KQ0 A;  1XGM A;  2GA2 A;  4IF7 A;  4IU6 A;  4IKR A;  3Q6D A;  4FLL A;  2DFI A;  4A6W A;  1QXZ A;  3IU8 A;  3PKB A;  1BN5 A;  1R5G A;  3L7G A;  5JHU A;  1WLR A;  2BWU A;  3CTZ A;  4FUK A;  1PV9 A;  2EVC A;  5CDL A;  3FM3 A;  2GG9 A;  2GGB A;  1YW7 A;  4U71 A;  3ROR A;  3BIQ A;  2EA4 A;  3PKC A;  1C22 A;  4S00 A;  4IKU A;  2Q93 A;  1YJ3 A;  4EGE A;  4U70 A;  1O0X A;  1KP0 A;  2B3L A;  2BWW A;  2P98 A;  4ZWP A;  3BIT A;  4IKT A;  4B28 A;  4U69 A;  2BWY A;  3CB5 A;  4U6J A;  5CE6 A;  3MX6 A;  2GG3 A;  1XGO A;  4ZWO A;  2GG7 A;  4U6E A;  2V3Z A;  2BHC A;  1W2M A;  1C23 A;  3IG4 A;  4IEC A;  4IKS A;  3PKA A;  4RGZ 1;  2B3K A;  1A16 A;  2P99 A;  5CNX A;  2NQ6 A;  4PV4 A;  4FLK A;  1N51 A;  1R5H A;  2Q95 A;  4U1B A;  1YW9 A;  1C27 A;  1YVM A;  1Y1N A;  1XGN A;  5JI6 A;  2GTX A;  4JUQ A; 
#chains in the Genus database with same CATH topology
 1C24 A;  2GG0 A;  4U6C A;  5D6E A;  2IW2 A;  2GU6 A;  1YW8 A;  5CIK A;  5FCF A;  4ZWU A;  1M35 A;  1C21 A;  4U73 A;  1QXY A;  5CDV A;  4FO7 A;  4HXX A;  1WBQ A;  2ADU A;  4RZY A;  1WL9 A;  2GU4 A;  2Q92 A;  2GG2 A;  3FMQ A;  3L24 A;  3PKD A;  2BWX A;  2OKN A;  1WL6 A;  4IPA A;  1BOA A;  2OAZ A;  3MR1 A;  3CB6 A;  1QZY A;  2BHA A;  4S2T P;  2BHB A;  4S01 A;  2BB7 A;  1W7V A;  1QXW A;  1XNZ A;  2V3X A;  3FMR A;  2G6P A;  1KQ9 A;  1WKM A;  3D27 A;  1JAW A;  2BWT A;  2GU5 A;  2BWV A;  2V6C A;  4U76 A;  1B6A A;  4KM3 A;  4Z7M A;  2P9A A;  4ZNG A;  4R60 A;  4U6Z A;  3TB5 A;  3RVA A;  2MAT A;  4MAT A;  5JFR A;  2BHD A;  3BIP A;  4FLJ A;  5FCH A;  2Q8K A;  4FO8 A;  4OOK A;  3TAV A;  1WY2 A;  2HOW A;  2Q94 A;  4S2R P;  2EVM A;  5D6F A;  2NQ7 A;  4QR8 A;  5CLS A;  4RZZ A;  4U75 A;  4FKC A;  2BWS A;  2GG8 A;  3IU9 A;  2BN7 A;  2GZ5 A;  5E5B A;  1XGS A;  2ZSG A;  4IDY A;  4FLI A;  3MAT A;  2BH3 A;  4PNC A;  1B59 A;  5CDE A;  1WN1 A;  1CHM A;  2GGC A;  2GU7 A;  2V3Y A;  3PKE A;  4U6W A;  3S6B A;  2EA2 A;  3IU7 A;  4A6V A;  1R58 A;  2B3H A;  2Q96 A;  2EVO A;  1MAT A;  2GG5 A;  1KQ0 A;  1XGM A;  2GA2 A;  4IF7 A;  4IU6 A;  4IKR A;  3Q6D A;  4FLL A;  2DFI A;  4A6W A;  1QXZ A;  3IU8 A;  3PKB A;  1BN5 A;  1R5G A;  3L7G A;  5JHU A;  1WLR A;  2BWU A;  3CTZ A;  4FUK A;  1PV9 A;  2EVC A;  5CDL A;  3FM3 A;  2GG9 A;  2GGB A;  1YW7 A;  4U71 A;  3ROR A;  3BIQ A;  2EA4 A;  3PKC A;  1C22 A;  4S00 A;  4IKU A;  2Q93 A;  1YJ3 A;  4EGE A;  4U70 A;  1O0X A;  1KP0 A;  2B3L A;  2BWW A;  2P98 A;  4ZWP A;  3BIT A;  4IKT A;  4B28 A;  4U69 A;  2BWY A;  3CB5 A;  4U6J A;  5CE6 A;  3MX6 A;  2GG3 A;  1XGO A;  4ZWO A;  2GG7 A;  4U6E A;  2V3Z A;  2BHC A;  1W2M A;  1C23 A;  3IG4 A;  4IEC A;  4IKS A;  3PKA A;  4RGZ 1;  2B3K A;  1A16 A;  2P99 A;  5CNX A;  2NQ6 A;  4PV4 A;  4FLK A;  1N51 A;  1R5H A;  2Q95 A;  4U1B A;  1YW9 A;  1C27 A;  1YVM A;  1Y1N A;  1XGN A;  5JI6 A;  2GTX A;  4JUQ A; 
#chains in the Genus database with same CATH homology
 1C24 A;  2GG0 A;  4U6C A;  5D6E A;  2IW2 A;  2GU6 A;  1YW8 A;  5CIK A;  5FCF A;  4ZWU A;  1M35 A;  1C21 A;  4U73 A;  1QXY A;  5CDV A;  4FO7 A;  4HXX A;  1WBQ A;  2ADU A;  4RZY A;  1WL9 A;  2GU4 A;  2Q92 A;  2GG2 A;  3FMQ A;  3L24 A;  3PKD A;  2BWX A;  2OKN A;  1WL6 A;  4IPA A;  1BOA A;  2OAZ A;  3MR1 A;  3CB6 A;  1QZY A;  2BHA A;  4S2T P;  2BHB A;  4S01 A;  2BB7 A;  1W7V A;  1QXW A;  1XNZ A;  2V3X A;  3FMR A;  2G6P A;  1KQ9 A;  1WKM A;  3D27 A;  1JAW A;  2BWT A;  2GU5 A;  2BWV A;  2V6C A;  4U76 A;  1B6A A;  4KM3 A;  4Z7M A;  2P9A A;  4ZNG A;  4R60 A;  4U6Z A;  3TB5 A;  3RVA A;  2MAT A;  4MAT A;  5JFR A;  2BHD A;  3BIP A;  4FLJ A;  5FCH A;  2Q8K A;  4FO8 A;  4OOK A;  3TAV A;  1WY2 A;  2HOW A;  2Q94 A;  4S2R P;  2EVM A;  5D6F A;  2NQ7 A;  4QR8 A;  5CLS A;  4RZZ A;  4U75 A;  4FKC A;  2BWS A;  2GG8 A;  3IU9 A;  2BN7 A;  2GZ5 A;  5E5B A;  1XGS A;  2ZSG A;  4IDY A;  4FLI A;  3MAT A;  2BH3 A;  4PNC A;  1B59 A;  5CDE A;  1WN1 A;  1CHM A;  2GGC A;  2GU7 A;  2V3Y A;  3PKE A;  4U6W A;  3S6B A;  2EA2 A;  3IU7 A;  4A6V A;  1R58 A;  2B3H A;  2Q96 A;  2EVO A;  1MAT A;  2GG5 A;  1KQ0 A;  1XGM A;  2GA2 A;  4IF7 A;  4IU6 A;  4IKR A;  3Q6D A;  4FLL A;  2DFI A;  4A6W A;  1QXZ A;  3IU8 A;  3PKB A;  1BN5 A;  1R5G A;  3L7G A;  5JHU A;  1WLR A;  2BWU A;  3CTZ A;  4FUK A;  1PV9 A;  2EVC A;  5CDL A;  3FM3 A;  2GG9 A;  2GGB A;  1YW7 A;  4U71 A;  3ROR A;  3BIQ A;  2EA4 A;  3PKC A;  1C22 A;  4S00 A;  4IKU A;  2Q93 A;  1YJ3 A;  4EGE A;  4U70 A;  1O0X A;  1KP0 A;  2B3L A;  2BWW A;  2P98 A;  4ZWP A;  3BIT A;  4IKT A;  4B28 A;  4U69 A;  2BWY A;  3CB5 A;  4U6J A;  5CE6 A;  3MX6 A;  2GG3 A;  1XGO A;  4ZWO A;  2GG7 A;  4U6E A;  2V3Z A;  2BHC A;  1W2M A;  1C23 A;  3IG4 A;  4IEC A;  4IKS A;  3PKA A;  4RGZ 1;  2B3K A;  1A16 A;  2P99 A;  5CNX A;  2NQ6 A;  4PV4 A;  4FLK A;  1N51 A;  1R5H A;  2Q95 A;  4U1B A;  1YW9 A;  1C27 A;  1YVM A;  1Y1N A;  1XGN A;  5JI6 A;  2GTX A;  4JUQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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