3L7GA

Crystal structure of organophosphate anhydrolase/prolidase
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
440
structure length
425
Chain Sequence
MNKLAVLYAEHIATLQKRTREIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPVIDNPHCWIVANGTDKPKLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQVEKLLPYDKARFAYIGEYLEVAQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQGHKAARDAFFQGKSEFEIQQAYLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRSFLIDAGANFNGYAADITRTYDFTGEGEFAELVATMKQHQIALMNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIGLQVHDVGGFMALRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRIEDNIIVHEDSLENMTRELRLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase.
pubmed doi rcsb
molecule tags Hydrolase
source organism Alteromonas sp.
molecule keywords Xaa-Pro dipeptidase
total genus 143
structure length 425
sequence length 440
chains with identical sequence B, C
ec nomenclature ec 3.1.8.1: Aryldialkylphosphatase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 3l7gA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3l7gA02
2BWVA 2EVMA 1XGNA 4S00A 5JFRA 2ZSGA 2BHDA 3RVAA 5CDLA 4U69A 2Q93A 4FLLA 5D6FA 4A6VA 2P99A 4EGEA 4RZZA 1WL9A 1WY2A 3CB5A 4IKTA 2ADUA 2GG3A 2BWXA 3BIPA 2BHCA 1C23A 3L7GA 3D27A 4S2TP 1O0XA 1W2MA 3MX6A 2DFIA 4U6JA 1QXYA 2BWUA 1JAWA 2V3XA 1XGOA 2GU7A 2GG9A 4U70A 3PKCA 2BWTA 3PKEA 4MATA 3PKDA 1WN1A 4IKRA 3I7MA 3L24A 2GG5A 4JUQA 3PEBA 2BWSA 4Z7MA 2V3ZA 1MATA 4U75A 2BWYA 1BOAA 1C21A 4FKCA 1YW7A 1WBQA 5FCFA 2G6PA 3S6BA 4U71A 1YJ3A 3PKBA 3MATA 1N51A 2MATA 4S2RP 2BHBA 1QXWA 1KQ0A 2OAZA 5CNXA 3FMQA 4ZWPA 2B3KA 2BB7A 4IECA 3QOCA 1R58A 1YW8A 3IU9A 4IF7A 4PNCA 4U6CA 1WLRA 4IDYA 3Q6DA 2EA2A 4HXXA 5CDVA 1QZYA 1B59A 1BN5A 4A6WA 2GGCA 4U1BA 4OOKA 2EA4A 2EVCA 4IKSA 4IU6A 5CE6A 5E5BA 1YW9A 2GZ5A 2V6CA 4RZYA 4QR8A 2V3YA 1C22A 2GA2A 3OVKA 4U73A 4U6WA 3IG4A 3TB5A 2GTXA 3BIQA 5CLSA 4FO8A 4B28A 3CTZA 2GG2A 2BWWA 1XGSA 1Y1NA 5E2CA 4IPAA 2NQ6A 2BH3A 4PV4A 1R5HA 4FLJA 1C27A 2GGBA 3FMRA 2BN7A 3BITA 2NQ7A 2IW2A 1M35A 3RORA 2GG8A 3MR1A 5JHUA 1KP0A 2GG0A 1XNZA 4FUKA 2GU6A 4U6EA 2GG7A 3FM3A 1XGMA 4R60A 2B3HA 3O5VA 1PV9A 4FLIA 4U6ZA 3OOOA 2BHAA 4IKUA 2HOWA 5D6EA 5CIKA 1KQ9A 2Q94A 2B3LA 1R5GA 4U76A 2GU4A 1WL6A 2Q96A 4ZNGA 2GU5A 3IL0A 3IU8A 4FO7A 2P9AA 1CHMA 5CDEA 1WKMA 4ZWUA 1A16A 5FCHA 3PKAA 2EVOA 1B6AA 3CB6A 2OKNA 4S01A 1W7VA 4RGZ1 5JI6A 2Q95A 4KM3A 3PN9A 4ZWOA 2P98A 2Q92A 1C24A 3IU7A 4FLKA 1YVMA 2Q8KA 3TAVA 1QXZA
chains in the Genus database with same CATH superfamily
2BWVA 2EVMA 1XGNA 4S00A 5JFRA 2ZSGA 2BHDA 3RVAA 5CDLA 4U69A 2Q93A 4FLLA 5D6FA 4A6VA 2P99A 4EGEA 4RZZA 1WL9A 1WY2A 3CB5A 4IKTA 2ADUA 2GG3A 2BWXA 3BIPA 2BHCA 1C23A 3L7GA 3D27A 4S2TP 1O0XA 1W2MA 3MX6A 2DFIA 4U6JA 1QXYA 2BWUA 1JAWA 2V3XA 1XGOA 2GU7A 2GG9A 4U70A 3PKCA 2BWTA 3PKEA 4MATA 3PKDA 1WN1A 4IKRA 3I7MA 3L24A 2GG5A 4JUQA 3PEBA 2BWSA 4Z7MA 2V3ZA 1MATA 4U75A 2BWYA 1BOAA 1C21A 4FKCA 1YW7A 1WBQA 5FCFA 2G6PA 3S6BA 4U71A 1YJ3A 3PKBA 3MATA 1N51A 2MATA 4S2RP 2BHBA 1QXWA 1KQ0A 2OAZA 5CNXA 3FMQA 4ZWPA 2B3KA 2BB7A 4IECA 3QOCA 1R58A 1YW8A 3IU9A 4IF7A 4PNCA 4U6CA 1WLRA 4IDYA 3Q6DA 2EA2A 4HXXA 5CDVA 1QZYA 1B59A 1BN5A 4A6WA 2GGCA 4U1BA 4OOKA 2EA4A 2EVCA 4IKSA 4IU6A 5CE6A 5E5BA 1YW9A 2GZ5A 2V6CA 4RZYA 4QR8A 2V3YA 1C22A 2GA2A 3OVKA 4U73A 4U6WA 3IG4A 3TB5A 2GTXA 3BIQA 5CLSA 4FO8A 4B28A 3CTZA 2GG2A 2BWWA 1XGSA 1Y1NA 5E2CA 4IPAA 2NQ6A 2BH3A 4PV4A 1R5HA 4FLJA 1C27A 2GGBA 3FMRA 2BN7A 3BITA 2NQ7A 2IW2A 1M35A 3RORA 2GG8A 3MR1A 5JHUA 1KP0A 2GG0A 1XNZA 4FUKA 2GU6A 4U6EA 2GG7A 3FM3A 1XGMA 4R60A 2B3HA 3O5VA 1PV9A 4FLIA 4U6ZA 3OOOA 2BHAA 4IKUA 2HOWA 5D6EA 5CIKA 1KQ9A 2Q94A 2B3LA 1R5GA 4U76A 2GU4A 1WL6A 2Q96A 4ZNGA 2GU5A 3IL0A 3IU8A 4FO7A 2P9AA 1CHMA 5CDEA 1WKMA 4ZWUA 1A16A 5FCHA 3PKAA 2EVOA 1B6AA 3CB6A 2OKNA 4S01A 1W7VA 4RGZ1 5JI6A 2Q95A 4KM3A 3PN9A 4ZWOA 2P98A 2Q92A 1C24A 3IU7A 4FLKA 1YVMA 2Q8KA 3TAVA 1QXZA
chains in the Genus database with same CATH topology
2BWVA 2EVMA 1XGNA 4S00A 5JFRA 2ZSGA 2BHDA 3RVAA 5CDLA 4U69A 2Q93A 4FLLA 5D6FA 4A6VA 2P99A 4EGEA 4RZZA 1WL9A 1WY2A 3CB5A 4IKTA 2ADUA 2GG3A 2BWXA 3BIPA 2BHCA 1C23A 3L7GA 3D27A 4S2TP 1O0XA 1W2MA 3MX6A 2DFIA 4U6JA 1QXYA 2BWUA 1JAWA 2V3XA 1XGOA 2GU7A 2GG9A 4U70A 3PKCA 2BWTA 3PKEA 4MATA 3PKDA 1WN1A 4IKRA 3I7MA 3L24A 2GG5A 4JUQA 3PEBA 2BWSA 4Z7MA 2V3ZA 1MATA 4U75A 2BWYA 1BOAA 1C21A 4FKCA 1YW7A 1WBQA 5FCFA 2G6PA 3S6BA 4U71A 1YJ3A 3PKBA 3MATA 1N51A 2MATA 4S2RP 2BHBA 1QXWA 1KQ0A 2OAZA 5CNXA 3FMQA 4ZWPA 2B3KA 2BB7A 4IECA 3QOCA 1R58A 1YW8A 3IU9A 4IF7A 4PNCA 4U6CA 1WLRA 4IDYA 3Q6DA 2EA2A 4HXXA 5CDVA 1QZYA 1B59A 1BN5A 4A6WA 2GGCA 4U1BA 4OOKA 2EA4A 2EVCA 4IKSA 4IU6A 5CE6A 5E5BA 1YW9A 2GZ5A 2V6CA 4RZYA 4QR8A 2V3YA 1C22A 2GA2A 3OVKA 4U73A 4U6WA 3IG4A 3TB5A 2GTXA 3BIQA 5CLSA 4FO8A 4B28A 3CTZA 2GG2A 2BWWA 1XGSA 1Y1NA 5E2CA 4IPAA 2NQ6A 2BH3A 4PV4A 1R5HA 4FLJA 1C27A 2GGBA 3FMRA 2BN7A 3BITA 2NQ7A 2IW2A 1M35A 3RORA 2GG8A 3MR1A 5JHUA 1KP0A 2GG0A 1XNZA 4FUKA 2GU6A 4U6EA 2GG7A 3FM3A 1XGMA 4R60A 2B3HA 3O5VA 1PV9A 4FLIA 4U6ZA 3OOOA 2BHAA 4IKUA 2HOWA 5D6EA 5CIKA 1KQ9A 2Q94A 2B3LA 1R5GA 4U76A 2GU4A 1WL6A 2Q96A 4ZNGA 2GU5A 3IL0A 3IU8A 4FO7A 2P9AA 1CHMA 5CDEA 1WKMA 4ZWUA 1A16A 5FCHA 3PKAA 2EVOA 1B6AA 3CB6A 2OKNA 4S01A 1W7VA 4RGZ1 5JI6A 2Q95A 4KM3A 3PN9A 4ZWOA 2P98A 2Q92A 1C24A 3IU7A 4FLKA 1YVMA 2Q8KA 3TAVA 1QXZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BWV A;  2EVM A;  1XGN A;  4S00 A;  5JFR A;  2ZSG A;  2BHD A;  3RVA A;  5CDL A;  4U69 A;  2Q93 A;  4FLL A;  5D6F A;  4A6V A;  2P99 A;  4EGE A;  4RZZ A;  1WL9 A;  1WY2 A;  3CB5 A;  4IKT A;  2ADU A;  2GG3 A;  2BWX A;  3BIP A;  2BHC A;  1C23 A;  3L7G A;  3D27 A;  4S2T P;  1O0X A;  1W2M A;  3MX6 A;  2DFI A;  4U6J A;  1QXY A;  2BWU A;  1JAW A;  2V3X A;  1XGO A;  2GU7 A;  2GG9 A;  4U70 A;  3PKC A;  2BWT A;  3PKE A;  4MAT A;  3PKD A;  1WN1 A;  4IKR A;  3I7M A;  3L24 A;  2GG5 A;  4JUQ A;  3PEB A;  2BWS A;  4Z7M A;  2V3Z A;  1MAT A;  4U75 A;  2BWY A;  1BOA A;  1C21 A;  4FKC A;  1YW7 A;  1WBQ A;  5FCF A;  2G6P A;  3S6B A;  4U71 A;  1YJ3 A;  3PKB A;  3MAT A;  1N51 A;  2MAT A;  4S2R P;  2BHB A;  1QXW A;  1KQ0 A;  2OAZ A;  5CNX A;  3FMQ A;  4ZWP A;  2B3K A;  2BB7 A;  4IEC A;  3QOC A;  1R58 A;  1YW8 A;  3IU9 A;  4IF7 A;  4PNC A;  4U6C A;  1WLR A;  4IDY A;  3Q6D A;  2EA2 A;  4HXX A;  5CDV A;  1QZY A;  1B59 A;  1BN5 A;  4A6W A;  2GGC A;  4U1B A;  4OOK A;  2EA4 A;  2EVC A;  4IKS A;  4IU6 A;  5CE6 A;  5E5B A;  1YW9 A;  2GZ5 A;  2V6C A;  4RZY A;  4QR8 A;  2V3Y A;  1C22 A;  2GA2 A;  3OVK A;  4U73 A;  4U6W A;  3IG4 A;  3TB5 A;  2GTX A;  3BIQ A;  5CLS A;  4FO8 A;  4B28 A;  3CTZ A;  2GG2 A;  2BWW A;  1XGS A;  1Y1N A;  5E2C A;  4IPA A;  2NQ6 A;  2BH3 A;  4PV4 A;  1R5H A;  4FLJ A;  1C27 A;  2GGB A;  3FMR A;  2BN7 A;  3BIT A;  2NQ7 A;  2IW2 A;  1M35 A;  3ROR A;  2GG8 A;  3MR1 A;  5JHU A;  1KP0 A;  2GG0 A;  1XNZ A;  4FUK A;  2GU6 A;  4U6E A;  2GG7 A;  3FM3 A;  1XGM A;  4R60 A;  2B3H A;  3O5V A;  1PV9 A;  4FLI A;  4U6Z A;  3OOO A;  2BHA A;  4IKU A;  2HOW A;  5D6E A;  5CIK A;  1KQ9 A;  2Q94 A;  2B3L A;  1R5G A;  4U76 A;  2GU4 A;  1WL6 A;  2Q96 A;  4ZNG A;  2GU5 A;  3IL0 A;  3IU8 A;  4FO7 A;  2P9A A;  1CHM A;  5CDE A;  1WKM A;  4ZWU A;  1A16 A;  5FCH A;  3PKA A;  2EVO A;  1B6A A;  3CB6 A;  2OKN A;  4S01 A;  1W7V A;  4RGZ 1;  5JI6 A;  2Q95 A;  4KM3 A;  3PN9 A;  4ZWO A;  2P98 A;  2Q92 A;  1C24 A;  3IU7 A;  4FLK A;  1YVM A;  2Q8K A;  3TAV A;  1QXZ A; 
#chains in the Genus database with same CATH topology
 2BWV A;  2EVM A;  1XGN A;  4S00 A;  5JFR A;  2ZSG A;  2BHD A;  3RVA A;  5CDL A;  4U69 A;  2Q93 A;  4FLL A;  5D6F A;  4A6V A;  2P99 A;  4EGE A;  4RZZ A;  1WL9 A;  1WY2 A;  3CB5 A;  4IKT A;  2ADU A;  2GG3 A;  2BWX A;  3BIP A;  2BHC A;  1C23 A;  3L7G A;  3D27 A;  4S2T P;  1O0X A;  1W2M A;  3MX6 A;  2DFI A;  4U6J A;  1QXY A;  2BWU A;  1JAW A;  2V3X A;  1XGO A;  2GU7 A;  2GG9 A;  4U70 A;  3PKC A;  2BWT A;  3PKE A;  4MAT A;  3PKD A;  1WN1 A;  4IKR A;  3I7M A;  3L24 A;  2GG5 A;  4JUQ A;  3PEB A;  2BWS A;  4Z7M A;  2V3Z A;  1MAT A;  4U75 A;  2BWY A;  1BOA A;  1C21 A;  4FKC A;  1YW7 A;  1WBQ A;  5FCF A;  2G6P A;  3S6B A;  4U71 A;  1YJ3 A;  3PKB A;  3MAT A;  1N51 A;  2MAT A;  4S2R P;  2BHB A;  1QXW A;  1KQ0 A;  2OAZ A;  5CNX A;  3FMQ A;  4ZWP A;  2B3K A;  2BB7 A;  4IEC A;  3QOC A;  1R58 A;  1YW8 A;  3IU9 A;  4IF7 A;  4PNC A;  4U6C A;  1WLR A;  4IDY A;  3Q6D A;  2EA2 A;  4HXX A;  5CDV A;  1QZY A;  1B59 A;  1BN5 A;  4A6W A;  2GGC A;  4U1B A;  4OOK A;  2EA4 A;  2EVC A;  4IKS A;  4IU6 A;  5CE6 A;  5E5B A;  1YW9 A;  2GZ5 A;  2V6C A;  4RZY A;  4QR8 A;  2V3Y A;  1C22 A;  2GA2 A;  3OVK A;  4U73 A;  4U6W A;  3IG4 A;  3TB5 A;  2GTX A;  3BIQ A;  5CLS A;  4FO8 A;  4B28 A;  3CTZ A;  2GG2 A;  2BWW A;  1XGS A;  1Y1N A;  5E2C A;  4IPA A;  2NQ6 A;  2BH3 A;  4PV4 A;  1R5H A;  4FLJ A;  1C27 A;  2GGB A;  3FMR A;  2BN7 A;  3BIT A;  2NQ7 A;  2IW2 A;  1M35 A;  3ROR A;  2GG8 A;  3MR1 A;  5JHU A;  1KP0 A;  2GG0 A;  1XNZ A;  4FUK A;  2GU6 A;  4U6E A;  2GG7 A;  3FM3 A;  1XGM A;  4R60 A;  2B3H A;  3O5V A;  1PV9 A;  4FLI A;  4U6Z A;  3OOO A;  2BHA A;  4IKU A;  2HOW A;  5D6E A;  5CIK A;  1KQ9 A;  2Q94 A;  2B3L A;  1R5G A;  4U76 A;  2GU4 A;  1WL6 A;  2Q96 A;  4ZNG A;  2GU5 A;  3IL0 A;  3IU8 A;  4FO7 A;  2P9A A;  1CHM A;  5CDE A;  1WKM A;  4ZWU A;  1A16 A;  5FCH A;  3PKA A;  2EVO A;  1B6A A;  3CB6 A;  2OKN A;  4S01 A;  1W7V A;  4RGZ 1;  5JI6 A;  2Q95 A;  4KM3 A;  3PN9 A;  4ZWO A;  2P98 A;  2Q92 A;  1C24 A;  3IU7 A;  4FLK A;  1YVM A;  2Q8K A;  3TAV A;  1QXZ A; 
#chains in the Genus database with same CATH homology
 2BWV A;  2EVM A;  1XGN A;  4S00 A;  5JFR A;  2ZSG A;  2BHD A;  3RVA A;  5CDL A;  4U69 A;  2Q93 A;  4FLL A;  5D6F A;  4A6V A;  2P99 A;  4EGE A;  4RZZ A;  1WL9 A;  1WY2 A;  3CB5 A;  4IKT A;  2ADU A;  2GG3 A;  2BWX A;  3BIP A;  2BHC A;  1C23 A;  3L7G A;  3D27 A;  4S2T P;  1O0X A;  1W2M A;  3MX6 A;  2DFI A;  4U6J A;  1QXY A;  2BWU A;  1JAW A;  2V3X A;  1XGO A;  2GU7 A;  2GG9 A;  4U70 A;  3PKC A;  2BWT A;  3PKE A;  4MAT A;  3PKD A;  1WN1 A;  4IKR A;  3I7M A;  3L24 A;  2GG5 A;  4JUQ A;  3PEB A;  2BWS A;  4Z7M A;  2V3Z A;  1MAT A;  4U75 A;  2BWY A;  1BOA A;  1C21 A;  4FKC A;  1YW7 A;  1WBQ A;  5FCF A;  2G6P A;  3S6B A;  4U71 A;  1YJ3 A;  3PKB A;  3MAT A;  1N51 A;  2MAT A;  4S2R P;  2BHB A;  1QXW A;  1KQ0 A;  2OAZ A;  5CNX A;  3FMQ A;  4ZWP A;  2B3K A;  2BB7 A;  4IEC A;  3QOC A;  1R58 A;  1YW8 A;  3IU9 A;  4IF7 A;  4PNC A;  4U6C A;  1WLR A;  4IDY A;  3Q6D A;  2EA2 A;  4HXX A;  5CDV A;  1QZY A;  1B59 A;  1BN5 A;  4A6W A;  2GGC A;  4U1B A;  4OOK A;  2EA4 A;  2EVC A;  4IKS A;  4IU6 A;  5CE6 A;  5E5B A;  1YW9 A;  2GZ5 A;  2V6C A;  4RZY A;  4QR8 A;  2V3Y A;  1C22 A;  2GA2 A;  3OVK A;  4U73 A;  4U6W A;  3IG4 A;  3TB5 A;  2GTX A;  3BIQ A;  5CLS A;  4FO8 A;  4B28 A;  3CTZ A;  2GG2 A;  2BWW A;  1XGS A;  1Y1N A;  5E2C A;  4IPA A;  2NQ6 A;  2BH3 A;  4PV4 A;  1R5H A;  4FLJ A;  1C27 A;  2GGB A;  3FMR A;  2BN7 A;  3BIT A;  2NQ7 A;  2IW2 A;  1M35 A;  3ROR A;  2GG8 A;  3MR1 A;  5JHU A;  1KP0 A;  2GG0 A;  1XNZ A;  4FUK A;  2GU6 A;  4U6E A;  2GG7 A;  3FM3 A;  1XGM A;  4R60 A;  2B3H A;  3O5V A;  1PV9 A;  4FLI A;  4U6Z A;  3OOO A;  2BHA A;  4IKU A;  2HOW A;  5D6E A;  5CIK A;  1KQ9 A;  2Q94 A;  2B3L A;  1R5G A;  4U76 A;  2GU4 A;  1WL6 A;  2Q96 A;  4ZNG A;  2GU5 A;  3IL0 A;  3IU8 A;  4FO7 A;  2P9A A;  1CHM A;  5CDE A;  1WKM A;  4ZWU A;  1A16 A;  5FCH A;  3PKA A;  2EVO A;  1B6A A;  3CB6 A;  2OKN A;  4S01 A;  1W7V A;  4RGZ 1;  5JI6 A;  2Q95 A;  4KM3 A;  3PN9 A;  4ZWO A;  2P98 A;  2Q92 A;  1C24 A;  3IU7 A;  4FLK A;  1YVM A;  2Q8K A;  3TAV A;  1QXZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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