3L7GA

Crystal structure of organophosphate anhydrolase/prolidase
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
440
structure length
425
Chain Sequence
MNKLAVLYAEHIATLQKRTREIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPVIDNPHCWIVANGTDKPKLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQVEKLLPYDKARFAYIGEYLEVAQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQGHKAARDAFFQGKSEFEIQQAYLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRSFLIDAGANFNGYAADITRTYDFTGEGEFAELVATMKQHQIALMNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIGLQVHDVGGFMALRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRIEDNIIVHEDSLENMTRELRLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
publication title Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase.
pubmed doi rcsb
source organism Alteromonas sp.
molecule tags Hydrolase
total genus 143
structure length 425
sequence length 440
chains with identical sequence B, C
ec nomenclature ec 3.1.8.1: Aryldialkylphosphatase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 3l7gA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3l7gA02
3PN9A 4R60A 3IL0A 2GZ5A 2P98A 3IU7A 4FLLA 4FLIA 1MATA 5CDEA 3L7GA 4OOKA 1KQ9A 2BWSA 4U71A 1WY2A 5CDVA 5E5BA 2Q96A 4FLJA 2EA4A 5FCFA 5E2CA 4B28A 2B3HA 1R58A 4U70A 2P9AA 4U73A 4A6WA 2BWWA 3FM3A 4FO8A 3MR1A 2IW2A 1XNZA 3L24A 4U6CA 4U6WA 4IF7A 2BHBA 2BHDA 2OKNA 2BHAA 1WL6A 3MATA 1Y1NA 2BHCA 2Q8KA 3IG4A 2GG0A 5CNXA 2V3YA 2Q94A 1WKMA 2OAZA 1C27A 4IECA 2ZSGA 4U69A 2HOWA 3QOCA 2DFIA 3PKCA 2B3KA 4S00A 5CIKA 1KQ0A 2GG5A 1QXZA 4Z7MA 2EVCA 4S2RP 2B3LA 2GG7A 3BIPA 1XGMA 4U6EA 1C23A 1W7VA 2G6PA 2BB7A 3CB6A 4FKCA 3IU8A 2P99A 2GU6A 1WN1A 2GG8A 1YW9A 1R5GA 1YW8A 2EA2A 3Q6DA 1WLRA 2GGBA 4FUKA 3PKEA 4PNCA 2BWXA 4FLKA 4QR8A 2GGCA 1C24A 1WL9A 1YJ3A 5CLSA 3S6BA 5CE6A 1M35A 4HXXA 2Q95A 1C21A 3TB5A 1YW7A 3PKAA 3FMRA 2Q93A 1BOAA 2BWTA 2GU5A 4ZWUA 2GTXA 1B59A 4IDYA 3BITA 2BH3A 4U1BA 2BWYA 2NQ6A 2V3ZA 4IKSA 5D6EA 3D27A 3PEBA 1O0XA 1R5HA 4EGEA 2MATA 3TAVA 3IU9A 4KM3A 2BWVA 2V6CA 3OVKA 4S2TP 4U6JA 3I7MA 1XGNA 1W2MA 1QXYA 1WBQA 1XGOA 3RVAA 4IKUA 4U75A 1YVMA 3RORA 4IKRA 4A6VA 4IU6A 5CDLA 5D6FA 1A16A 1C22A 1XGSA 1JAWA 3PKDA 3PKBA 4ZNGA 4MATA 4RGZ1 3CB5A 1KP0A 1QXWA 2GU7A 1PV9A 4JUQA 4FO7A 2BN7A 5JHUA 2GA2A 2ADUA 2GG3A 4RZZA 4ZWOA 4IKTA 5JFRA 1CHMA 3BIQA 1BN5A 2NQ7A 3OOOA 2V3XA 1N51A 5FCHA 3CTZA 4PV4A 2GG2A 3FMQA 2GU4A 3O5VA 4RZYA 4U76A 3MX6A 4U6ZA 4ZWPA 2GG9A 4S01A 2Q92A 2EVMA 2BWUA 1QZYA 2EVOA 4IPAA 5JI6A 1B6AA
chains in the Genus database with same CATH superfamily
3PN9A 4R60A 3IL0A 2GZ5A 2P98A 3IU7A 4FLLA 4FLIA 1MATA 5CDEA 3L7GA 4OOKA 1KQ9A 2BWSA 4U71A 1WY2A 5CDVA 5E5BA 2Q96A 4FLJA 2EA4A 5FCFA 5E2CA 4B28A 2B3HA 1R58A 4U70A 2P9AA 4U73A 4A6WA 2BWWA 3FM3A 4FO8A 3MR1A 2IW2A 1XNZA 3L24A 4U6CA 4U6WA 4IF7A 2BHBA 2BHDA 2OKNA 2BHAA 1WL6A 3MATA 1Y1NA 2BHCA 2Q8KA 3IG4A 2GG0A 5CNXA 2V3YA 2Q94A 1WKMA 2OAZA 1C27A 4IECA 2ZSGA 4U69A 2HOWA 3QOCA 2DFIA 3PKCA 2B3KA 4S00A 5CIKA 1KQ0A 2GG5A 1QXZA 4Z7MA 2EVCA 4S2RP 2B3LA 2GG7A 3BIPA 1XGMA 4U6EA 1C23A 1W7VA 2G6PA 2BB7A 3CB6A 4FKCA 3IU8A 2P99A 2GU6A 1WN1A 2GG8A 1YW9A 1R5GA 1YW8A 2EA2A 3Q6DA 1WLRA 2GGBA 4FUKA 3PKEA 4PNCA 2BWXA 4FLKA 4QR8A 2GGCA 1C24A 1WL9A 1YJ3A 5CLSA 3S6BA 5CE6A 1M35A 4HXXA 2Q95A 1C21A 3TB5A 1YW7A 3PKAA 3FMRA 2Q93A 1BOAA 2BWTA 2GU5A 4ZWUA 2GTXA 1B59A 4IDYA 3BITA 2BH3A 4U1BA 2BWYA 2NQ6A 2V3ZA 4IKSA 5D6EA 3D27A 3PEBA 1O0XA 1R5HA 4EGEA 2MATA 3TAVA 3IU9A 4KM3A 2BWVA 2V6CA 3OVKA 4S2TP 4U6JA 3I7MA 1XGNA 1W2MA 1QXYA 1WBQA 1XGOA 3RVAA 4IKUA 4U75A 1YVMA 3RORA 4IKRA 4A6VA 4IU6A 5CDLA 5D6FA 1A16A 1C22A 1XGSA 1JAWA 3PKDA 3PKBA 4ZNGA 4MATA 4RGZ1 3CB5A 1KP0A 1QXWA 2GU7A 1PV9A 4JUQA 4FO7A 2BN7A 5JHUA 2GA2A 2ADUA 2GG3A 4RZZA 4ZWOA 4IKTA 5JFRA 1CHMA 3BIQA 1BN5A 2NQ7A 3OOOA 2V3XA 1N51A 5FCHA 3CTZA 4PV4A 2GG2A 3FMQA 2GU4A 3O5VA 4RZYA 4U76A 3MX6A 4U6ZA 4ZWPA 2GG9A 4S01A 2Q92A 2EVMA 2BWUA 1QZYA 2EVOA 4IPAA 5JI6A 1B6AA
chains in the Genus database with same CATH topology
3PN9A 4R60A 3IL0A 2GZ5A 2P98A 3IU7A 4FLLA 4FLIA 1MATA 5CDEA 3L7GA 4OOKA 1KQ9A 2BWSA 4U71A 1WY2A 5CDVA 5E5BA 2Q96A 4FLJA 2EA4A 5FCFA 5E2CA 4B28A 2B3HA 1R58A 4U70A 2P9AA 4U73A 4A6WA 2BWWA 3FM3A 4FO8A 3MR1A 2IW2A 1XNZA 3L24A 4U6CA 4U6WA 4IF7A 2BHBA 2BHDA 2OKNA 2BHAA 1WL6A 3MATA 1Y1NA 2BHCA 2Q8KA 3IG4A 2GG0A 5CNXA 2V3YA 2Q94A 1WKMA 2OAZA 1C27A 4IECA 2ZSGA 4U69A 2HOWA 3QOCA 2DFIA 3PKCA 2B3KA 4S00A 5CIKA 1KQ0A 2GG5A 1QXZA 4Z7MA 2EVCA 4S2RP 2B3LA 2GG7A 3BIPA 1XGMA 4U6EA 1C23A 1W7VA 2G6PA 2BB7A 3CB6A 4FKCA 3IU8A 2P99A 2GU6A 1WN1A 2GG8A 1YW9A 1R5GA 1YW8A 2EA2A 3Q6DA 1WLRA 2GGBA 4FUKA 3PKEA 4PNCA 2BWXA 4FLKA 4QR8A 2GGCA 1C24A 1WL9A 1YJ3A 5CLSA 3S6BA 5CE6A 1M35A 4HXXA 2Q95A 1C21A 3TB5A 1YW7A 3PKAA 3FMRA 2Q93A 1BOAA 2BWTA 2GU5A 4ZWUA 2GTXA 1B59A 4IDYA 3BITA 2BH3A 4U1BA 2BWYA 2NQ6A 2V3ZA 4IKSA 5D6EA 3D27A 3PEBA 1O0XA 1R5HA 4EGEA 2MATA 3TAVA 3IU9A 4KM3A 2BWVA 2V6CA 3OVKA 4S2TP 4U6JA 3I7MA 1XGNA 1W2MA 1QXYA 1WBQA 1XGOA 3RVAA 4IKUA 4U75A 1YVMA 3RORA 4IKRA 4A6VA 4IU6A 5CDLA 5D6FA 1A16A 1C22A 1XGSA 1JAWA 3PKDA 3PKBA 4ZNGA 4MATA 4RGZ1 3CB5A 1KP0A 1QXWA 2GU7A 1PV9A 4JUQA 4FO7A 2BN7A 5JHUA 2GA2A 2ADUA 2GG3A 4RZZA 4ZWOA 4IKTA 5JFRA 1CHMA 3BIQA 1BN5A 2NQ7A 3OOOA 2V3XA 1N51A 5FCHA 3CTZA 4PV4A 2GG2A 3FMQA 2GU4A 3O5VA 4RZYA 4U76A 3MX6A 4U6ZA 4ZWPA 2GG9A 4S01A 2Q92A 2EVMA 2BWUA 1QZYA 2EVOA 4IPAA 5JI6A 1B6AA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PN9 A;  4R60 A;  3IL0 A;  2GZ5 A;  2P98 A;  3IU7 A;  4FLL A;  4FLI A;  1MAT A;  5CDE A;  3L7G A;  4OOK A;  1KQ9 A;  2BWS A;  4U71 A;  1WY2 A;  5CDV A;  5E5B A;  2Q96 A;  4FLJ A;  2EA4 A;  5FCF A;  5E2C A;  4B28 A;  2B3H A;  1R58 A;  4U70 A;  2P9A A;  4U73 A;  4A6W A;  2BWW A;  3FM3 A;  4FO8 A;  3MR1 A;  2IW2 A;  1XNZ A;  3L24 A;  4U6C A;  4U6W A;  4IF7 A;  2BHB A;  2BHD A;  2OKN A;  2BHA A;  1WL6 A;  3MAT A;  1Y1N A;  2BHC A;  2Q8K A;  3IG4 A;  2GG0 A;  5CNX A;  2V3Y A;  2Q94 A;  1WKM A;  2OAZ A;  1C27 A;  4IEC A;  2ZSG A;  4U69 A;  2HOW A;  3QOC A;  2DFI A;  3PKC A;  2B3K A;  4S00 A;  5CIK A;  1KQ0 A;  2GG5 A;  1QXZ A;  4Z7M A;  2EVC A;  4S2R P;  2B3L A;  2GG7 A;  3BIP A;  1XGM A;  4U6E A;  1C23 A;  1W7V A;  2G6P A;  2BB7 A;  3CB6 A;  4FKC A;  3IU8 A;  2P99 A;  2GU6 A;  1WN1 A;  2GG8 A;  1YW9 A;  1R5G A;  1YW8 A;  2EA2 A;  3Q6D A;  1WLR A;  2GGB A;  4FUK A;  3PKE A;  4PNC A;  2BWX A;  4FLK A;  4QR8 A;  2GGC A;  1C24 A;  1WL9 A;  1YJ3 A;  5CLS A;  3S6B A;  5CE6 A;  1M35 A;  4HXX A;  2Q95 A;  1C21 A;  3TB5 A;  1YW7 A;  3PKA A;  3FMR A;  2Q93 A;  1BOA A;  2BWT A;  2GU5 A;  4ZWU A;  2GTX A;  1B59 A;  4IDY A;  3BIT A;  2BH3 A;  4U1B A;  2BWY A;  2NQ6 A;  2V3Z A;  4IKS A;  5D6E A;  3D27 A;  3PEB A;  1O0X A;  1R5H A;  4EGE A;  2MAT A;  3TAV A;  3IU9 A;  4KM3 A;  2BWV A;  2V6C A;  3OVK A;  4S2T P;  4U6J A;  3I7M A;  1XGN A;  1W2M A;  1QXY A;  1WBQ A;  1XGO A;  3RVA A;  4IKU A;  4U75 A;  1YVM A;  3ROR A;  4IKR A;  4A6V A;  4IU6 A;  5CDL A;  5D6F A;  1A16 A;  1C22 A;  1XGS A;  1JAW A;  3PKD A;  3PKB A;  4ZNG A;  4MAT A;  4RGZ 1;  3CB5 A;  1KP0 A;  1QXW A;  2GU7 A;  1PV9 A;  4JUQ A;  4FO7 A;  2BN7 A;  5JHU A;  2GA2 A;  2ADU A;  2GG3 A;  4RZZ A;  4ZWO A;  4IKT A;  5JFR A;  1CHM A;  3BIQ A;  1BN5 A;  2NQ7 A;  3OOO A;  2V3X A;  1N51 A;  5FCH A;  3CTZ A;  4PV4 A;  2GG2 A;  3FMQ A;  2GU4 A;  3O5V A;  4RZY A;  4U76 A;  3MX6 A;  4U6Z A;  4ZWP A;  2GG9 A;  4S01 A;  2Q92 A;  2EVM A;  2BWU A;  1QZY A;  2EVO A;  4IPA A;  5JI6 A;  1B6A A; 
#chains in the Genus database with same CATH topology
 3PN9 A;  4R60 A;  3IL0 A;  2GZ5 A;  2P98 A;  3IU7 A;  4FLL A;  4FLI A;  1MAT A;  5CDE A;  3L7G A;  4OOK A;  1KQ9 A;  2BWS A;  4U71 A;  1WY2 A;  5CDV A;  5E5B A;  2Q96 A;  4FLJ A;  2EA4 A;  5FCF A;  5E2C A;  4B28 A;  2B3H A;  1R58 A;  4U70 A;  2P9A A;  4U73 A;  4A6W A;  2BWW A;  3FM3 A;  4FO8 A;  3MR1 A;  2IW2 A;  1XNZ A;  3L24 A;  4U6C A;  4U6W A;  4IF7 A;  2BHB A;  2BHD A;  2OKN A;  2BHA A;  1WL6 A;  3MAT A;  1Y1N A;  2BHC A;  2Q8K A;  3IG4 A;  2GG0 A;  5CNX A;  2V3Y A;  2Q94 A;  1WKM A;  2OAZ A;  1C27 A;  4IEC A;  2ZSG A;  4U69 A;  2HOW A;  3QOC A;  2DFI A;  3PKC A;  2B3K A;  4S00 A;  5CIK A;  1KQ0 A;  2GG5 A;  1QXZ A;  4Z7M A;  2EVC A;  4S2R P;  2B3L A;  2GG7 A;  3BIP A;  1XGM A;  4U6E A;  1C23 A;  1W7V A;  2G6P A;  2BB7 A;  3CB6 A;  4FKC A;  3IU8 A;  2P99 A;  2GU6 A;  1WN1 A;  2GG8 A;  1YW9 A;  1R5G A;  1YW8 A;  2EA2 A;  3Q6D A;  1WLR A;  2GGB A;  4FUK A;  3PKE A;  4PNC A;  2BWX A;  4FLK A;  4QR8 A;  2GGC A;  1C24 A;  1WL9 A;  1YJ3 A;  5CLS A;  3S6B A;  5CE6 A;  1M35 A;  4HXX A;  2Q95 A;  1C21 A;  3TB5 A;  1YW7 A;  3PKA A;  3FMR A;  2Q93 A;  1BOA A;  2BWT A;  2GU5 A;  4ZWU A;  2GTX A;  1B59 A;  4IDY A;  3BIT A;  2BH3 A;  4U1B A;  2BWY A;  2NQ6 A;  2V3Z A;  4IKS A;  5D6E A;  3D27 A;  3PEB A;  1O0X A;  1R5H A;  4EGE A;  2MAT A;  3TAV A;  3IU9 A;  4KM3 A;  2BWV A;  2V6C A;  3OVK A;  4S2T P;  4U6J A;  3I7M A;  1XGN A;  1W2M A;  1QXY A;  1WBQ A;  1XGO A;  3RVA A;  4IKU A;  4U75 A;  1YVM A;  3ROR A;  4IKR A;  4A6V A;  4IU6 A;  5CDL A;  5D6F A;  1A16 A;  1C22 A;  1XGS A;  1JAW A;  3PKD A;  3PKB A;  4ZNG A;  4MAT A;  4RGZ 1;  3CB5 A;  1KP0 A;  1QXW A;  2GU7 A;  1PV9 A;  4JUQ A;  4FO7 A;  2BN7 A;  5JHU A;  2GA2 A;  2ADU A;  2GG3 A;  4RZZ A;  4ZWO A;  4IKT A;  5JFR A;  1CHM A;  3BIQ A;  1BN5 A;  2NQ7 A;  3OOO A;  2V3X A;  1N51 A;  5FCH A;  3CTZ A;  4PV4 A;  2GG2 A;  3FMQ A;  2GU4 A;  3O5V A;  4RZY A;  4U76 A;  3MX6 A;  4U6Z A;  4ZWP A;  2GG9 A;  4S01 A;  2Q92 A;  2EVM A;  2BWU A;  1QZY A;  2EVO A;  4IPA A;  5JI6 A;  1B6A A; 
#chains in the Genus database with same CATH homology
 3PN9 A;  4R60 A;  3IL0 A;  2GZ5 A;  2P98 A;  3IU7 A;  4FLL A;  4FLI A;  1MAT A;  5CDE A;  3L7G A;  4OOK A;  1KQ9 A;  2BWS A;  4U71 A;  1WY2 A;  5CDV A;  5E5B A;  2Q96 A;  4FLJ A;  2EA4 A;  5FCF A;  5E2C A;  4B28 A;  2B3H A;  1R58 A;  4U70 A;  2P9A A;  4U73 A;  4A6W A;  2BWW A;  3FM3 A;  4FO8 A;  3MR1 A;  2IW2 A;  1XNZ A;  3L24 A;  4U6C A;  4U6W A;  4IF7 A;  2BHB A;  2BHD A;  2OKN A;  2BHA A;  1WL6 A;  3MAT A;  1Y1N A;  2BHC A;  2Q8K A;  3IG4 A;  2GG0 A;  5CNX A;  2V3Y A;  2Q94 A;  1WKM A;  2OAZ A;  1C27 A;  4IEC A;  2ZSG A;  4U69 A;  2HOW A;  3QOC A;  2DFI A;  3PKC A;  2B3K A;  4S00 A;  5CIK A;  1KQ0 A;  2GG5 A;  1QXZ A;  4Z7M A;  2EVC A;  4S2R P;  2B3L A;  2GG7 A;  3BIP A;  1XGM A;  4U6E A;  1C23 A;  1W7V A;  2G6P A;  2BB7 A;  3CB6 A;  4FKC A;  3IU8 A;  2P99 A;  2GU6 A;  1WN1 A;  2GG8 A;  1YW9 A;  1R5G A;  1YW8 A;  2EA2 A;  3Q6D A;  1WLR A;  2GGB A;  4FUK A;  3PKE A;  4PNC A;  2BWX A;  4FLK A;  4QR8 A;  2GGC A;  1C24 A;  1WL9 A;  1YJ3 A;  5CLS A;  3S6B A;  5CE6 A;  1M35 A;  4HXX A;  2Q95 A;  1C21 A;  3TB5 A;  1YW7 A;  3PKA A;  3FMR A;  2Q93 A;  1BOA A;  2BWT A;  2GU5 A;  4ZWU A;  2GTX A;  1B59 A;  4IDY A;  3BIT A;  2BH3 A;  4U1B A;  2BWY A;  2NQ6 A;  2V3Z A;  4IKS A;  5D6E A;  3D27 A;  3PEB A;  1O0X A;  1R5H A;  4EGE A;  2MAT A;  3TAV A;  3IU9 A;  4KM3 A;  2BWV A;  2V6C A;  3OVK A;  4S2T P;  4U6J A;  3I7M A;  1XGN A;  1W2M A;  1QXY A;  1WBQ A;  1XGO A;  3RVA A;  4IKU A;  4U75 A;  1YVM A;  3ROR A;  4IKR A;  4A6V A;  4IU6 A;  5CDL A;  5D6F A;  1A16 A;  1C22 A;  1XGS A;  1JAW A;  3PKD A;  3PKB A;  4ZNG A;  4MAT A;  4RGZ 1;  3CB5 A;  1KP0 A;  1QXW A;  2GU7 A;  1PV9 A;  4JUQ A;  4FO7 A;  2BN7 A;  5JHU A;  2GA2 A;  2ADU A;  2GG3 A;  4RZZ A;  4ZWO A;  4IKT A;  5JFR A;  1CHM A;  3BIQ A;  1BN5 A;  2NQ7 A;  3OOO A;  2V3X A;  1N51 A;  5FCH A;  3CTZ A;  4PV4 A;  2GG2 A;  3FMQ A;  2GU4 A;  3O5V A;  4RZY A;  4U76 A;  3MX6 A;  4U6Z A;  4ZWP A;  2GG9 A;  4S01 A;  2Q92 A;  2EVM A;  2BWU A;  1QZY A;  2EVO A;  4IPA A;  5JI6 A;  1B6A A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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