3L7GA

Crystal structure of organophosphate anhydrolase/prolidase
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
440
structure length
425
Chain Sequence
b'MNKLAVLYAEHIATLQKRTREIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPVIDNPHCWIVANGTDKPKLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQVEKLLPYDKARFAYIGEYLEVAQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQGHKAARDAFFQGKSEFEIQQAYLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRSFLIDAGANFNGYAADITRTYDFTGEGEFAELVATMKQHQIALMNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIGLQVHDVGGFMALRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRIEDNIIVHEDSLENMTRELRLR'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
molecule tags Hydrolase
source organism Alteromonas sp.
publication title Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase.
pubmed doi rcsb
total genus 143
structure length 425
sequence length 440
chains with identical sequence B, C
ec nomenclature ec 3.1.8.1: Aryldialkylphosphatase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 3l7gA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3l7gA02
4OOKA 4FO7A 2ADUA 1WLRA 5D6EA 1B59A 3MX6A 1XGSA 1B6AA 2GTXA 4A6VA 1WL9A 2GZ5A 4U76A 4S2RP 1C21A 3PKAA 2GGBA 3IG4A 4U70A 2BWYA 3BIQA 3D27A 3OOOA 2BH3A 4IECA 4U6EA 2BN7A 2GU6A 4PNCA 4U75A 1PV9A 4R60A 2BWWA 4IF7A 1KQ0A 2Q8KA 2B3HA 1QZYA 2Q92A 2NQ7A 1CHMA 2GG2A 5CDEA 3RORA 3BITA 5CLSA 2V3XA 5CIKA 3BIPA 1Y1NA 4U69A 4RGZ1 1W2MA 2EA4A 1BOAA 2BHDA 2EA2A 3QOCA 1N51A 2BWXA 4HXXA 5JHUA 4RZYA 1MATA 4U6CA 2GU5A 4U6ZA 5CDLA 4MATA 3I7MA 1XNZA 1WY2A 4Z7MA 2GG3A 2BB7A 1W7VA 3CB5A 4S2TP 2OAZA 5JFRA 2BWSA 2EVOA 4QR8A 4ZWUA 1R5GA 1YW8A 2HOWA 2GG5A 4IKUA 2DFIA 1R58A 2MATA 2BWVA 3L24A 5FCHA 4S00A 4A6WA 4ZWOA 3PN9A 1A16A 3IU7A 2V3YA 4FKCA 4S01A 2Q94A 3MR1A 4B28A 4U6WA 5JI6A 4IKRA 4PV4A 3RVAA 3OVKA 1YJ3A 2GGCA 2GU7A 1QXWA 1XGNA 1R5HA 2GG0A 2P9AA 2BHBA 3PKBA 4FO8A 3PKCA 3L7GA 4IKSA 1C23A 2GA2A 4IU6A 2BHCA 3TAVA 2BHAA 4FUKA 1C27A 2V3ZA 1WL6A 4IDYA 3IL0A 2V6CA 4JUQA 4U1BA 1QXYA 2Q96A 4RZZA 3IU8A 4KM3A 1JAWA 5D6FA 4IKTA 3S6BA 4U6JA 1C24A 1KP0A 3MATA 2ZSGA 4FLKA 2BWTA 2GG8A 2P98A 3PKDA 4FLJA 5CDVA 4U71A 3FMQA 1M35A 3Q6DA 1C22A 2NQ6A 4U73A 3PEBA 2IW2A 1WKMA 2EVCA 1YVMA 4EGEA 2GG9A 2Q95A 4FLIA 2GG7A 1WBQA 2BWUA 5CNXA 1XGMA 3CB6A 2Q93A 3PKEA 4IPAA 3TB5A 4ZNGA 3O5VA 2B3LA 2G6PA 5CE6A 2OKNA 1YW7A 2GU4A 1YW9A 5E5BA 1WN1A 4ZWPA 1BN5A 1KQ9A 1XGOA 2B3KA 4FLLA 1QXZA 5FCFA 2P99A 3IU9A 3FM3A 1O0XA 3FMRA 3CTZA 5E2CA 2EVMA
chains in the Genus database with same CATH superfamily
4OOKA 4FO7A 2ADUA 1WLRA 5D6EA 1B59A 3MX6A 1XGSA 1B6AA 2GTXA 4A6VA 1WL9A 2GZ5A 4U76A 4S2RP 1C21A 3PKAA 2GGBA 3IG4A 4U70A 2BWYA 3BIQA 3D27A 3OOOA 2BH3A 4IECA 4U6EA 2BN7A 2GU6A 4PNCA 4U75A 1PV9A 4R60A 2BWWA 4IF7A 1KQ0A 2Q8KA 2B3HA 1QZYA 2Q92A 2NQ7A 1CHMA 2GG2A 5CDEA 3RORA 3BITA 5CLSA 2V3XA 5CIKA 3BIPA 1Y1NA 4U69A 4RGZ1 1W2MA 2EA4A 1BOAA 2BHDA 2EA2A 3QOCA 1N51A 2BWXA 4HXXA 5JHUA 4RZYA 1MATA 4U6CA 2GU5A 4U6ZA 5CDLA 4MATA 3I7MA 1XNZA 1WY2A 4Z7MA 2GG3A 2BB7A 1W7VA 3CB5A 4S2TP 2OAZA 5JFRA 2BWSA 2EVOA 4QR8A 4ZWUA 1R5GA 1YW8A 2HOWA 2GG5A 4IKUA 2DFIA 1R58A 2MATA 2BWVA 3L24A 5FCHA 4S00A 4A6WA 4ZWOA 3PN9A 1A16A 3IU7A 2V3YA 4FKCA 4S01A 2Q94A 3MR1A 4B28A 4U6WA 5JI6A 4IKRA 4PV4A 3RVAA 3OVKA 1YJ3A 2GGCA 2GU7A 1QXWA 1XGNA 1R5HA 2GG0A 2P9AA 2BHBA 3PKBA 4FO8A 3PKCA 3L7GA 4IKSA 1C23A 2GA2A 4IU6A 2BHCA 3TAVA 2BHAA 4FUKA 1C27A 2V3ZA 1WL6A 4IDYA 3IL0A 2V6CA 4JUQA 4U1BA 1QXYA 2Q96A 4RZZA 3IU8A 4KM3A 1JAWA 5D6FA 4IKTA 3S6BA 4U6JA 1C24A 1KP0A 3MATA 2ZSGA 4FLKA 2BWTA 2GG8A 2P98A 3PKDA 4FLJA 5CDVA 4U71A 3FMQA 1M35A 3Q6DA 1C22A 2NQ6A 4U73A 3PEBA 2IW2A 1WKMA 2EVCA 1YVMA 4EGEA 2GG9A 2Q95A 4FLIA 2GG7A 1WBQA 2BWUA 5CNXA 1XGMA 3CB6A 2Q93A 3PKEA 4IPAA 3TB5A 4ZNGA 3O5VA 2B3LA 2G6PA 5CE6A 2OKNA 1YW7A 2GU4A 1YW9A 5E5BA 1WN1A 4ZWPA 1BN5A 1KQ9A 1XGOA 2B3KA 4FLLA 1QXZA 5FCFA 2P99A 3IU9A 3FM3A 1O0XA 3FMRA 3CTZA 5E2CA 2EVMA
chains in the Genus database with same CATH topology
4OOKA 4FO7A 2ADUA 1WLRA 5D6EA 1B59A 3MX6A 1XGSA 1B6AA 2GTXA 4A6VA 1WL9A 2GZ5A 4U76A 4S2RP 1C21A 3PKAA 2GGBA 3IG4A 4U70A 2BWYA 3BIQA 3D27A 3OOOA 2BH3A 4IECA 4U6EA 2BN7A 2GU6A 4PNCA 4U75A 1PV9A 4R60A 2BWWA 4IF7A 1KQ0A 2Q8KA 2B3HA 1QZYA 2Q92A 2NQ7A 1CHMA 2GG2A 5CDEA 3RORA 3BITA 5CLSA 2V3XA 5CIKA 3BIPA 1Y1NA 4U69A 4RGZ1 1W2MA 2EA4A 1BOAA 2BHDA 2EA2A 3QOCA 1N51A 2BWXA 4HXXA 5JHUA 4RZYA 1MATA 4U6CA 2GU5A 4U6ZA 5CDLA 4MATA 3I7MA 1XNZA 1WY2A 4Z7MA 2GG3A 2BB7A 1W7VA 3CB5A 4S2TP 2OAZA 5JFRA 2BWSA 2EVOA 4QR8A 4ZWUA 1R5GA 1YW8A 2HOWA 2GG5A 4IKUA 2DFIA 1R58A 2MATA 2BWVA 3L24A 5FCHA 4S00A 4A6WA 4ZWOA 3PN9A 1A16A 3IU7A 2V3YA 4FKCA 4S01A 2Q94A 3MR1A 4B28A 4U6WA 5JI6A 4IKRA 4PV4A 3RVAA 3OVKA 1YJ3A 2GGCA 2GU7A 1QXWA 1XGNA 1R5HA 2GG0A 2P9AA 2BHBA 3PKBA 4FO8A 3PKCA 3L7GA 4IKSA 1C23A 2GA2A 4IU6A 2BHCA 3TAVA 2BHAA 4FUKA 1C27A 2V3ZA 1WL6A 4IDYA 3IL0A 2V6CA 4JUQA 4U1BA 1QXYA 2Q96A 4RZZA 3IU8A 4KM3A 1JAWA 5D6FA 4IKTA 3S6BA 4U6JA 1C24A 1KP0A 3MATA 2ZSGA 4FLKA 2BWTA 2GG8A 2P98A 3PKDA 4FLJA 5CDVA 4U71A 3FMQA 1M35A 3Q6DA 1C22A 2NQ6A 4U73A 3PEBA 2IW2A 1WKMA 2EVCA 1YVMA 4EGEA 2GG9A 2Q95A 4FLIA 2GG7A 1WBQA 2BWUA 5CNXA 1XGMA 3CB6A 2Q93A 3PKEA 4IPAA 3TB5A 4ZNGA 3O5VA 2B3LA 2G6PA 5CE6A 2OKNA 1YW7A 2GU4A 1YW9A 5E5BA 1WN1A 4ZWPA 1BN5A 1KQ9A 1XGOA 2B3KA 4FLLA 1QXZA 5FCFA 2P99A 3IU9A 3FM3A 1O0XA 3FMRA 3CTZA 5E2CA 2EVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4OOK A;  4FO7 A;  2ADU A;  1WLR A;  5D6E A;  1B59 A;  3MX6 A;  1XGS A;  1B6A A;  2GTX A;  4A6V A;  1WL9 A;  2GZ5 A;  4U76 A;  4S2R P;  1C21 A;  3PKA A;  2GGB A;  3IG4 A;  4U70 A;  2BWY A;  3BIQ A;  3D27 A;  3OOO A;  2BH3 A;  4IEC A;  4U6E A;  2BN7 A;  2GU6 A;  4PNC A;  4U75 A;  1PV9 A;  4R60 A;  2BWW A;  4IF7 A;  1KQ0 A;  2Q8K A;  2B3H A;  1QZY A;  2Q92 A;  2NQ7 A;  1CHM A;  2GG2 A;  5CDE A;  3ROR A;  3BIT A;  5CLS A;  2V3X A;  5CIK A;  3BIP A;  1Y1N A;  4U69 A;  4RGZ 1;  1W2M A;  2EA4 A;  1BOA A;  2BHD A;  2EA2 A;  3QOC A;  1N51 A;  2BWX A;  4HXX A;  5JHU A;  4RZY A;  1MAT A;  4U6C A;  2GU5 A;  4U6Z A;  5CDL A;  4MAT A;  3I7M A;  1XNZ A;  1WY2 A;  4Z7M A;  2GG3 A;  2BB7 A;  1W7V A;  3CB5 A;  4S2T P;  2OAZ A;  5JFR A;  2BWS A;  2EVO A;  4QR8 A;  4ZWU A;  1R5G A;  1YW8 A;  2HOW A;  2GG5 A;  4IKU A;  2DFI A;  1R58 A;  2MAT A;  2BWV A;  3L24 A;  5FCH A;  4S00 A;  4A6W A;  4ZWO A;  3PN9 A;  1A16 A;  3IU7 A;  2V3Y A;  4FKC A;  4S01 A;  2Q94 A;  3MR1 A;  4B28 A;  4U6W A;  5JI6 A;  4IKR A;  4PV4 A;  3RVA A;  3OVK A;  1YJ3 A;  2GGC A;  2GU7 A;  1QXW A;  1XGN A;  1R5H A;  2GG0 A;  2P9A A;  2BHB A;  3PKB A;  4FO8 A;  3PKC A;  3L7G A;  4IKS A;  1C23 A;  2GA2 A;  4IU6 A;  2BHC A;  3TAV A;  2BHA A;  4FUK A;  1C27 A;  2V3Z A;  1WL6 A;  4IDY A;  3IL0 A;  2V6C A;  4JUQ A;  4U1B A;  1QXY A;  2Q96 A;  4RZZ A;  3IU8 A;  4KM3 A;  1JAW A;  5D6F A;  4IKT A;  3S6B A;  4U6J A;  1C24 A;  1KP0 A;  3MAT A;  2ZSG A;  4FLK A;  2BWT A;  2GG8 A;  2P98 A;  3PKD A;  4FLJ A;  5CDV A;  4U71 A;  3FMQ A;  1M35 A;  3Q6D A;  1C22 A;  2NQ6 A;  4U73 A;  3PEB A;  2IW2 A;  1WKM A;  2EVC A;  1YVM A;  4EGE A;  2GG9 A;  2Q95 A;  4FLI A;  2GG7 A;  1WBQ A;  2BWU A;  5CNX A;  1XGM A;  3CB6 A;  2Q93 A;  3PKE A;  4IPA A;  3TB5 A;  4ZNG A;  3O5V A;  2B3L A;  2G6P A;  5CE6 A;  2OKN A;  1YW7 A;  2GU4 A;  1YW9 A;  5E5B A;  1WN1 A;  4ZWP A;  1BN5 A;  1KQ9 A;  1XGO A;  2B3K A;  4FLL A;  1QXZ A;  5FCF A;  2P99 A;  3IU9 A;  3FM3 A;  1O0X A;  3FMR A;  3CTZ A;  5E2C A;  2EVM A; 
#chains in the Genus database with same CATH topology
 4OOK A;  4FO7 A;  2ADU A;  1WLR A;  5D6E A;  1B59 A;  3MX6 A;  1XGS A;  1B6A A;  2GTX A;  4A6V A;  1WL9 A;  2GZ5 A;  4U76 A;  4S2R P;  1C21 A;  3PKA A;  2GGB A;  3IG4 A;  4U70 A;  2BWY A;  3BIQ A;  3D27 A;  3OOO A;  2BH3 A;  4IEC A;  4U6E A;  2BN7 A;  2GU6 A;  4PNC A;  4U75 A;  1PV9 A;  4R60 A;  2BWW A;  4IF7 A;  1KQ0 A;  2Q8K A;  2B3H A;  1QZY A;  2Q92 A;  2NQ7 A;  1CHM A;  2GG2 A;  5CDE A;  3ROR A;  3BIT A;  5CLS A;  2V3X A;  5CIK A;  3BIP A;  1Y1N A;  4U69 A;  4RGZ 1;  1W2M A;  2EA4 A;  1BOA A;  2BHD A;  2EA2 A;  3QOC A;  1N51 A;  2BWX A;  4HXX A;  5JHU A;  4RZY A;  1MAT A;  4U6C A;  2GU5 A;  4U6Z A;  5CDL A;  4MAT A;  3I7M A;  1XNZ A;  1WY2 A;  4Z7M A;  2GG3 A;  2BB7 A;  1W7V A;  3CB5 A;  4S2T P;  2OAZ A;  5JFR A;  2BWS A;  2EVO A;  4QR8 A;  4ZWU A;  1R5G A;  1YW8 A;  2HOW A;  2GG5 A;  4IKU A;  2DFI A;  1R58 A;  2MAT A;  2BWV A;  3L24 A;  5FCH A;  4S00 A;  4A6W A;  4ZWO A;  3PN9 A;  1A16 A;  3IU7 A;  2V3Y A;  4FKC A;  4S01 A;  2Q94 A;  3MR1 A;  4B28 A;  4U6W A;  5JI6 A;  4IKR A;  4PV4 A;  3RVA A;  3OVK A;  1YJ3 A;  2GGC A;  2GU7 A;  1QXW A;  1XGN A;  1R5H A;  2GG0 A;  2P9A A;  2BHB A;  3PKB A;  4FO8 A;  3PKC A;  3L7G A;  4IKS A;  1C23 A;  2GA2 A;  4IU6 A;  2BHC A;  3TAV A;  2BHA A;  4FUK A;  1C27 A;  2V3Z A;  1WL6 A;  4IDY A;  3IL0 A;  2V6C A;  4JUQ A;  4U1B A;  1QXY A;  2Q96 A;  4RZZ A;  3IU8 A;  4KM3 A;  1JAW A;  5D6F A;  4IKT A;  3S6B A;  4U6J A;  1C24 A;  1KP0 A;  3MAT A;  2ZSG A;  4FLK A;  2BWT A;  2GG8 A;  2P98 A;  3PKD A;  4FLJ A;  5CDV A;  4U71 A;  3FMQ A;  1M35 A;  3Q6D A;  1C22 A;  2NQ6 A;  4U73 A;  3PEB A;  2IW2 A;  1WKM A;  2EVC A;  1YVM A;  4EGE A;  2GG9 A;  2Q95 A;  4FLI A;  2GG7 A;  1WBQ A;  2BWU A;  5CNX A;  1XGM A;  3CB6 A;  2Q93 A;  3PKE A;  4IPA A;  3TB5 A;  4ZNG A;  3O5V A;  2B3L A;  2G6P A;  5CE6 A;  2OKN A;  1YW7 A;  2GU4 A;  1YW9 A;  5E5B A;  1WN1 A;  4ZWP A;  1BN5 A;  1KQ9 A;  1XGO A;  2B3K A;  4FLL A;  1QXZ A;  5FCF A;  2P99 A;  3IU9 A;  3FM3 A;  1O0X A;  3FMR A;  3CTZ A;  5E2C A;  2EVM A; 
#chains in the Genus database with same CATH homology
 4OOK A;  4FO7 A;  2ADU A;  1WLR A;  5D6E A;  1B59 A;  3MX6 A;  1XGS A;  1B6A A;  2GTX A;  4A6V A;  1WL9 A;  2GZ5 A;  4U76 A;  4S2R P;  1C21 A;  3PKA A;  2GGB A;  3IG4 A;  4U70 A;  2BWY A;  3BIQ A;  3D27 A;  3OOO A;  2BH3 A;  4IEC A;  4U6E A;  2BN7 A;  2GU6 A;  4PNC A;  4U75 A;  1PV9 A;  4R60 A;  2BWW A;  4IF7 A;  1KQ0 A;  2Q8K A;  2B3H A;  1QZY A;  2Q92 A;  2NQ7 A;  1CHM A;  2GG2 A;  5CDE A;  3ROR A;  3BIT A;  5CLS A;  2V3X A;  5CIK A;  3BIP A;  1Y1N A;  4U69 A;  4RGZ 1;  1W2M A;  2EA4 A;  1BOA A;  2BHD A;  2EA2 A;  3QOC A;  1N51 A;  2BWX A;  4HXX A;  5JHU A;  4RZY A;  1MAT A;  4U6C A;  2GU5 A;  4U6Z A;  5CDL A;  4MAT A;  3I7M A;  1XNZ A;  1WY2 A;  4Z7M A;  2GG3 A;  2BB7 A;  1W7V A;  3CB5 A;  4S2T P;  2OAZ A;  5JFR A;  2BWS A;  2EVO A;  4QR8 A;  4ZWU A;  1R5G A;  1YW8 A;  2HOW A;  2GG5 A;  4IKU A;  2DFI A;  1R58 A;  2MAT A;  2BWV A;  3L24 A;  5FCH A;  4S00 A;  4A6W A;  4ZWO A;  3PN9 A;  1A16 A;  3IU7 A;  2V3Y A;  4FKC A;  4S01 A;  2Q94 A;  3MR1 A;  4B28 A;  4U6W A;  5JI6 A;  4IKR A;  4PV4 A;  3RVA A;  3OVK A;  1YJ3 A;  2GGC A;  2GU7 A;  1QXW A;  1XGN A;  1R5H A;  2GG0 A;  2P9A A;  2BHB A;  3PKB A;  4FO8 A;  3PKC A;  3L7G A;  4IKS A;  1C23 A;  2GA2 A;  4IU6 A;  2BHC A;  3TAV A;  2BHA A;  4FUK A;  1C27 A;  2V3Z A;  1WL6 A;  4IDY A;  3IL0 A;  2V6C A;  4JUQ A;  4U1B A;  1QXY A;  2Q96 A;  4RZZ A;  3IU8 A;  4KM3 A;  1JAW A;  5D6F A;  4IKT A;  3S6B A;  4U6J A;  1C24 A;  1KP0 A;  3MAT A;  2ZSG A;  4FLK A;  2BWT A;  2GG8 A;  2P98 A;  3PKD A;  4FLJ A;  5CDV A;  4U71 A;  3FMQ A;  1M35 A;  3Q6D A;  1C22 A;  2NQ6 A;  4U73 A;  3PEB A;  2IW2 A;  1WKM A;  2EVC A;  1YVM A;  4EGE A;  2GG9 A;  2Q95 A;  4FLI A;  2GG7 A;  1WBQ A;  2BWU A;  5CNX A;  1XGM A;  3CB6 A;  2Q93 A;  3PKE A;  4IPA A;  3TB5 A;  4ZNG A;  3O5V A;  2B3L A;  2G6P A;  5CE6 A;  2OKN A;  1YW7 A;  2GU4 A;  1YW9 A;  5E5B A;  1WN1 A;  4ZWP A;  1BN5 A;  1KQ9 A;  1XGO A;  2B3K A;  4FLL A;  1QXZ A;  5FCF A;  2P99 A;  3IU9 A;  3FM3 A;  1O0X A;  3FMR A;  3CTZ A;  5E2C A;  2EVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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