3L7GA

Crystal structure of organophosphate anhydrolase/prolidase
Total Genus 143
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
143
sequence length
440
structure length
425
Chain Sequence
MNKLAVLYAEHIATLQKRTREIIERENLDGVVFHSGQAKRQFLDDMYYPFKVNPQFKAWLPVIDNPHCWIVANGTDKPKLIFYRPVDFWHKVPDEPNEYWADYFDIELLVKPDQVEKLLPYDKARFAYIGEYLEVAQALGFELMNPEPVMNFYHYHRAYKTQYELACMREANKIAVQGHKAARDAFFQGKSEFEIQQAYLLATQHSENDNPYGNIVALNENCAILHYTHFDRVAPATHRSFLIDAGANFNGYAADITRTYDFTGEGEFAELVATMKQHQIALMNQLAPGKLYGELHLDCHQRVAQTLSDFNIVDLSADEIVAKGITSTFFPHGLGHHIGLQVHDVGGFMALRCTRKIEANQVFTIEPGLYFIDSLLGDLAATDNNQHINWDKVAELKPFGGIRIEDNIIVHEDSLENMTRELRLR
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
publication title Structural insights into the dual activities of the nerve agent degrading organophosphate anhydrolase/prolidase.
pubmed doi rcsb
source organism Alteromonas sp.
total genus 143
structure length 425
sequence length 440
chains with identical sequence B, C
ec nomenclature ec 3.1.8.1: Aryldialkylphosphatase.
pdb deposition date 2009-12-28

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 3l7gA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3l7gA02
3BIQA 2GGBA 4IKRA 4IF7A 3PKBA 1KQ0A 5CE6A 1MATA 4EGEA 4FO8A 4OOKA 4A6WA 3BIPA 2GU6A 2EA4A 2Q92A 1YW9A 2B3LA 2B3HA 1XGNA 2GG7A 2NQ7A 2BHCA 4Z7MA 2BHAA 1W2MA 1Y1NA 4FO7A 3TB5A 4FKCA 1WKMA 4ZWPA 4IKTA 3TAVA 3CB6A 1QXYA 3L24A 4U6WA 1YJ3A 4FUKA 4QR8A 2B3KA 2OKNA 1CHMA 3IL0A 1WL6A 5E2CA 1C27A 5CDEA 4IDYA 3QOCA 2ZSGA 4ZWOA 3MR1A 4PNCA 4U6ZA 4FLJA 1A16A 2BHBA 1C21A 1R5HA 1WLRA 3PKEA 1QXWA 5JHUA 4KM3A 3L7GA 4U6EA 2BWWA 2GZ5A 3IG4A 3PEBA 3FMQA 2NQ6A 1YW8A 4U6CA 3O5VA 4B28A 2GG3A 1YVMA 3D27A 2EVMA 2GU4A 2GG9A 4A6VA 2V3XA 5CDVA 5JFRA 2BWUA 4IPAA 3PKAA 2Q95A 3MX6A 1QXZA 5CLSA 2BWTA 2OAZA 4IU6A 4U71A 4R60A 5D6EA 1O0XA 1R5GA 3PKCA 2GG8A 2HOWA 4JUQA 3OVKA 1WN1A 2V6CA 2ADUA 2GA2A 3IU8A 1KP0A 1C23A 4MATA 1C24A 2Q96A 1B6AA 4FLIA 4U1BA 3CTZA 1XGOA 3MATA 2IW2A 4S2RP 2Q93A 4HXXA 4S00A 1XNZA 3PKDA 2P99A 4RZYA 2GGCA 2P9AA 1W7VA 4RGZ1 2BWYA 1M35A 1XGMA 3IU7A 2GG0A 1R58A 2BHDA 4U73A 1JAWA 1XGSA 5E5BA 5FCFA 4IECA 5JI6A 3BITA 3Q6DA 4U76A 1WY2A 2MATA 1QZYA 2EA2A 4FLLA 3IU9A 3RVAA 2BN7A 1WBQA 2V3ZA 5CDLA 1N51A 1C22A 2EVCA 2BH3A 1B59A 5FCHA 1YW7A 3FMRA 2Q8KA 1PV9A 2EVOA 4U69A 1KQ9A 2BWVA 3OOOA 3FM3A 2GU5A 3CB5A 4IKUA 2BB7A 2P98A 4ZWUA 2GTXA 3I7MA 4U75A 1BN5A 2GG2A 4S2TP 2DFIA 3RORA 4U6JA 3PN9A 4U70A 4S01A 2G6PA 2BWSA 2BWXA 4ZNGA 5CNXA 5CIKA 3S6BA 2V3YA 4PV4A 2GG5A 2Q94A 4FLKA 4IKSA 5D6FA 2GU7A 4RZZA 1WL9A 1BOAA
chains in the Genus database with same CATH superfamily
3BIQA 2GGBA 4IKRA 4IF7A 3PKBA 1KQ0A 5CE6A 1MATA 4EGEA 4FO8A 4OOKA 4A6WA 3BIPA 2GU6A 2EA4A 2Q92A 1YW9A 2B3LA 2B3HA 1XGNA 2GG7A 2NQ7A 2BHCA 4Z7MA 2BHAA 1W2MA 1Y1NA 4FO7A 3TB5A 4FKCA 1WKMA 4ZWPA 4IKTA 3TAVA 3CB6A 1QXYA 3L24A 4U6WA 1YJ3A 4FUKA 4QR8A 2B3KA 2OKNA 1CHMA 3IL0A 1WL6A 5E2CA 1C27A 5CDEA 4IDYA 3QOCA 2ZSGA 4ZWOA 3MR1A 4PNCA 4U6ZA 4FLJA 1A16A 2BHBA 1C21A 1R5HA 1WLRA 3PKEA 1QXWA 5JHUA 4KM3A 3L7GA 4U6EA 2BWWA 2GZ5A 3IG4A 3PEBA 3FMQA 2NQ6A 1YW8A 4U6CA 3O5VA 4B28A 2GG3A 1YVMA 3D27A 2EVMA 2GU4A 2GG9A 4A6VA 2V3XA 5CDVA 5JFRA 2BWUA 4IPAA 3PKAA 2Q95A 3MX6A 1QXZA 5CLSA 2BWTA 2OAZA 4IU6A 4U71A 4R60A 5D6EA 1O0XA 1R5GA 3PKCA 2GG8A 2HOWA 4JUQA 3OVKA 1WN1A 2V6CA 2ADUA 2GA2A 3IU8A 1KP0A 1C23A 4MATA 1C24A 2Q96A 1B6AA 4FLIA 4U1BA 3CTZA 1XGOA 3MATA 2IW2A 4S2RP 2Q93A 4HXXA 4S00A 1XNZA 3PKDA 2P99A 4RZYA 2GGCA 2P9AA 1W7VA 4RGZ1 2BWYA 1M35A 1XGMA 3IU7A 2GG0A 1R58A 2BHDA 4U73A 1JAWA 1XGSA 5E5BA 5FCFA 4IECA 5JI6A 3BITA 3Q6DA 4U76A 1WY2A 2MATA 1QZYA 2EA2A 4FLLA 3IU9A 3RVAA 2BN7A 1WBQA 2V3ZA 5CDLA 1N51A 1C22A 2EVCA 2BH3A 1B59A 5FCHA 1YW7A 3FMRA 2Q8KA 1PV9A 2EVOA 4U69A 1KQ9A 2BWVA 3OOOA 3FM3A 2GU5A 3CB5A 4IKUA 2BB7A 2P98A 4ZWUA 2GTXA 3I7MA 4U75A 1BN5A 2GG2A 4S2TP 2DFIA 3RORA 4U6JA 3PN9A 4U70A 4S01A 2G6PA 2BWSA 2BWXA 4ZNGA 5CNXA 5CIKA 3S6BA 2V3YA 4PV4A 2GG5A 2Q94A 4FLKA 4IKSA 5D6FA 2GU7A 4RZZA 1WL9A 1BOAA
chains in the Genus database with same CATH topology
3BIQA 2GGBA 4IKRA 4IF7A 3PKBA 1KQ0A 5CE6A 1MATA 4EGEA 4FO8A 4OOKA 4A6WA 3BIPA 2GU6A 2EA4A 2Q92A 1YW9A 2B3LA 2B3HA 1XGNA 2GG7A 2NQ7A 2BHCA 4Z7MA 2BHAA 1W2MA 1Y1NA 4FO7A 3TB5A 4FKCA 1WKMA 4ZWPA 4IKTA 3TAVA 3CB6A 1QXYA 3L24A 4U6WA 1YJ3A 4FUKA 4QR8A 2B3KA 2OKNA 1CHMA 3IL0A 1WL6A 5E2CA 1C27A 5CDEA 4IDYA 3QOCA 2ZSGA 4ZWOA 3MR1A 4PNCA 4U6ZA 4FLJA 1A16A 2BHBA 1C21A 1R5HA 1WLRA 3PKEA 1QXWA 5JHUA 4KM3A 3L7GA 4U6EA 2BWWA 2GZ5A 3IG4A 3PEBA 3FMQA 2NQ6A 1YW8A 4U6CA 3O5VA 4B28A 2GG3A 1YVMA 3D27A 2EVMA 2GU4A 2GG9A 4A6VA 2V3XA 5CDVA 5JFRA 2BWUA 4IPAA 3PKAA 2Q95A 3MX6A 1QXZA 5CLSA 2BWTA 2OAZA 4IU6A 4U71A 4R60A 5D6EA 1O0XA 1R5GA 3PKCA 2GG8A 2HOWA 4JUQA 3OVKA 1WN1A 2V6CA 2ADUA 2GA2A 3IU8A 1KP0A 1C23A 4MATA 1C24A 2Q96A 1B6AA 4FLIA 4U1BA 3CTZA 1XGOA 3MATA 2IW2A 4S2RP 2Q93A 4HXXA 4S00A 1XNZA 3PKDA 2P99A 4RZYA 2GGCA 2P9AA 1W7VA 4RGZ1 2BWYA 1M35A 1XGMA 3IU7A 2GG0A 1R58A 2BHDA 4U73A 1JAWA 1XGSA 5E5BA 5FCFA 4IECA 5JI6A 3BITA 3Q6DA 4U76A 1WY2A 2MATA 1QZYA 2EA2A 4FLLA 3IU9A 3RVAA 2BN7A 1WBQA 2V3ZA 5CDLA 1N51A 1C22A 2EVCA 2BH3A 1B59A 5FCHA 1YW7A 3FMRA 2Q8KA 1PV9A 2EVOA 4U69A 1KQ9A 2BWVA 3OOOA 3FM3A 2GU5A 3CB5A 4IKUA 2BB7A 2P98A 4ZWUA 2GTXA 3I7MA 4U75A 1BN5A 2GG2A 4S2TP 2DFIA 3RORA 4U6JA 3PN9A 4U70A 4S01A 2G6PA 2BWSA 2BWXA 4ZNGA 5CNXA 5CIKA 3S6BA 2V3YA 4PV4A 2GG5A 2Q94A 4FLKA 4IKSA 5D6FA 2GU7A 4RZZA 1WL9A 1BOAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3BIQ A;  2GGB A;  4IKR A;  4IF7 A;  3PKB A;  1KQ0 A;  5CE6 A;  1MAT A;  4EGE A;  4FO8 A;  4OOK A;  4A6W A;  3BIP A;  2GU6 A;  2EA4 A;  2Q92 A;  1YW9 A;  2B3L A;  2B3H A;  1XGN A;  2GG7 A;  2NQ7 A;  2BHC A;  4Z7M A;  2BHA A;  1W2M A;  1Y1N A;  4FO7 A;  3TB5 A;  4FKC A;  1WKM A;  4ZWP A;  4IKT A;  3TAV A;  3CB6 A;  1QXY A;  3L24 A;  4U6W A;  1YJ3 A;  4FUK A;  4QR8 A;  2B3K A;  2OKN A;  1CHM A;  3IL0 A;  1WL6 A;  5E2C A;  1C27 A;  5CDE A;  4IDY A;  3QOC A;  2ZSG A;  4ZWO A;  3MR1 A;  4PNC A;  4U6Z A;  4FLJ A;  1A16 A;  2BHB A;  1C21 A;  1R5H A;  1WLR A;  3PKE A;  1QXW A;  5JHU A;  4KM3 A;  3L7G A;  4U6E A;  2BWW A;  2GZ5 A;  3IG4 A;  3PEB A;  3FMQ A;  2NQ6 A;  1YW8 A;  4U6C A;  3O5V A;  4B28 A;  2GG3 A;  1YVM A;  3D27 A;  2EVM A;  2GU4 A;  2GG9 A;  4A6V A;  2V3X A;  5CDV A;  5JFR A;  2BWU A;  4IPA A;  3PKA A;  2Q95 A;  3MX6 A;  1QXZ A;  5CLS A;  2BWT A;  2OAZ A;  4IU6 A;  4U71 A;  4R60 A;  5D6E A;  1O0X A;  1R5G A;  3PKC A;  2GG8 A;  2HOW A;  4JUQ A;  3OVK A;  1WN1 A;  2V6C A;  2ADU A;  2GA2 A;  3IU8 A;  1KP0 A;  1C23 A;  4MAT A;  1C24 A;  2Q96 A;  1B6A A;  4FLI A;  4U1B A;  3CTZ A;  1XGO A;  3MAT A;  2IW2 A;  4S2R P;  2Q93 A;  4HXX A;  4S00 A;  1XNZ A;  3PKD A;  2P99 A;  4RZY A;  2GGC A;  2P9A A;  1W7V A;  4RGZ 1;  2BWY A;  1M35 A;  1XGM A;  3IU7 A;  2GG0 A;  1R58 A;  2BHD A;  4U73 A;  1JAW A;  1XGS A;  5E5B A;  5FCF A;  4IEC A;  5JI6 A;  3BIT A;  3Q6D A;  4U76 A;  1WY2 A;  2MAT A;  1QZY A;  2EA2 A;  4FLL A;  3IU9 A;  3RVA A;  2BN7 A;  1WBQ A;  2V3Z A;  5CDL A;  1N51 A;  1C22 A;  2EVC A;  2BH3 A;  1B59 A;  5FCH A;  1YW7 A;  3FMR A;  2Q8K A;  1PV9 A;  2EVO A;  4U69 A;  1KQ9 A;  2BWV A;  3OOO A;  3FM3 A;  2GU5 A;  3CB5 A;  4IKU A;  2BB7 A;  2P98 A;  4ZWU A;  2GTX A;  3I7M A;  4U75 A;  1BN5 A;  2GG2 A;  4S2T P;  2DFI A;  3ROR A;  4U6J A;  3PN9 A;  4U70 A;  4S01 A;  2G6P A;  2BWS A;  2BWX A;  4ZNG A;  5CNX A;  5CIK A;  3S6B A;  2V3Y A;  4PV4 A;  2GG5 A;  2Q94 A;  4FLK A;  4IKS A;  5D6F A;  2GU7 A;  4RZZ A;  1WL9 A;  1BOA A; 
#chains in the Genus database with same CATH topology
 3BIQ A;  2GGB A;  4IKR A;  4IF7 A;  3PKB A;  1KQ0 A;  5CE6 A;  1MAT A;  4EGE A;  4FO8 A;  4OOK A;  4A6W A;  3BIP A;  2GU6 A;  2EA4 A;  2Q92 A;  1YW9 A;  2B3L A;  2B3H A;  1XGN A;  2GG7 A;  2NQ7 A;  2BHC A;  4Z7M A;  2BHA A;  1W2M A;  1Y1N A;  4FO7 A;  3TB5 A;  4FKC A;  1WKM A;  4ZWP A;  4IKT A;  3TAV A;  3CB6 A;  1QXY A;  3L24 A;  4U6W A;  1YJ3 A;  4FUK A;  4QR8 A;  2B3K A;  2OKN A;  1CHM A;  3IL0 A;  1WL6 A;  5E2C A;  1C27 A;  5CDE A;  4IDY A;  3QOC A;  2ZSG A;  4ZWO A;  3MR1 A;  4PNC A;  4U6Z A;  4FLJ A;  1A16 A;  2BHB A;  1C21 A;  1R5H A;  1WLR A;  3PKE A;  1QXW A;  5JHU A;  4KM3 A;  3L7G A;  4U6E A;  2BWW A;  2GZ5 A;  3IG4 A;  3PEB A;  3FMQ A;  2NQ6 A;  1YW8 A;  4U6C A;  3O5V A;  4B28 A;  2GG3 A;  1YVM A;  3D27 A;  2EVM A;  2GU4 A;  2GG9 A;  4A6V A;  2V3X A;  5CDV A;  5JFR A;  2BWU A;  4IPA A;  3PKA A;  2Q95 A;  3MX6 A;  1QXZ A;  5CLS A;  2BWT A;  2OAZ A;  4IU6 A;  4U71 A;  4R60 A;  5D6E A;  1O0X A;  1R5G A;  3PKC A;  2GG8 A;  2HOW A;  4JUQ A;  3OVK A;  1WN1 A;  2V6C A;  2ADU A;  2GA2 A;  3IU8 A;  1KP0 A;  1C23 A;  4MAT A;  1C24 A;  2Q96 A;  1B6A A;  4FLI A;  4U1B A;  3CTZ A;  1XGO A;  3MAT A;  2IW2 A;  4S2R P;  2Q93 A;  4HXX A;  4S00 A;  1XNZ A;  3PKD A;  2P99 A;  4RZY A;  2GGC A;  2P9A A;  1W7V A;  4RGZ 1;  2BWY A;  1M35 A;  1XGM A;  3IU7 A;  2GG0 A;  1R58 A;  2BHD A;  4U73 A;  1JAW A;  1XGS A;  5E5B A;  5FCF A;  4IEC A;  5JI6 A;  3BIT A;  3Q6D A;  4U76 A;  1WY2 A;  2MAT A;  1QZY A;  2EA2 A;  4FLL A;  3IU9 A;  3RVA A;  2BN7 A;  1WBQ A;  2V3Z A;  5CDL A;  1N51 A;  1C22 A;  2EVC A;  2BH3 A;  1B59 A;  5FCH A;  1YW7 A;  3FMR A;  2Q8K A;  1PV9 A;  2EVO A;  4U69 A;  1KQ9 A;  2BWV A;  3OOO A;  3FM3 A;  2GU5 A;  3CB5 A;  4IKU A;  2BB7 A;  2P98 A;  4ZWU A;  2GTX A;  3I7M A;  4U75 A;  1BN5 A;  2GG2 A;  4S2T P;  2DFI A;  3ROR A;  4U6J A;  3PN9 A;  4U70 A;  4S01 A;  2G6P A;  2BWS A;  2BWX A;  4ZNG A;  5CNX A;  5CIK A;  3S6B A;  2V3Y A;  4PV4 A;  2GG5 A;  2Q94 A;  4FLK A;  4IKS A;  5D6F A;  2GU7 A;  4RZZ A;  1WL9 A;  1BOA A; 
#chains in the Genus database with same CATH homology
 3BIQ A;  2GGB A;  4IKR A;  4IF7 A;  3PKB A;  1KQ0 A;  5CE6 A;  1MAT A;  4EGE A;  4FO8 A;  4OOK A;  4A6W A;  3BIP A;  2GU6 A;  2EA4 A;  2Q92 A;  1YW9 A;  2B3L A;  2B3H A;  1XGN A;  2GG7 A;  2NQ7 A;  2BHC A;  4Z7M A;  2BHA A;  1W2M A;  1Y1N A;  4FO7 A;  3TB5 A;  4FKC A;  1WKM A;  4ZWP A;  4IKT A;  3TAV A;  3CB6 A;  1QXY A;  3L24 A;  4U6W A;  1YJ3 A;  4FUK A;  4QR8 A;  2B3K A;  2OKN A;  1CHM A;  3IL0 A;  1WL6 A;  5E2C A;  1C27 A;  5CDE A;  4IDY A;  3QOC A;  2ZSG A;  4ZWO A;  3MR1 A;  4PNC A;  4U6Z A;  4FLJ A;  1A16 A;  2BHB A;  1C21 A;  1R5H A;  1WLR A;  3PKE A;  1QXW A;  5JHU A;  4KM3 A;  3L7G A;  4U6E A;  2BWW A;  2GZ5 A;  3IG4 A;  3PEB A;  3FMQ A;  2NQ6 A;  1YW8 A;  4U6C A;  3O5V A;  4B28 A;  2GG3 A;  1YVM A;  3D27 A;  2EVM A;  2GU4 A;  2GG9 A;  4A6V A;  2V3X A;  5CDV A;  5JFR A;  2BWU A;  4IPA A;  3PKA A;  2Q95 A;  3MX6 A;  1QXZ A;  5CLS A;  2BWT A;  2OAZ A;  4IU6 A;  4U71 A;  4R60 A;  5D6E A;  1O0X A;  1R5G A;  3PKC A;  2GG8 A;  2HOW A;  4JUQ A;  3OVK A;  1WN1 A;  2V6C A;  2ADU A;  2GA2 A;  3IU8 A;  1KP0 A;  1C23 A;  4MAT A;  1C24 A;  2Q96 A;  1B6A A;  4FLI A;  4U1B A;  3CTZ A;  1XGO A;  3MAT A;  2IW2 A;  4S2R P;  2Q93 A;  4HXX A;  4S00 A;  1XNZ A;  3PKD A;  2P99 A;  4RZY A;  2GGC A;  2P9A A;  1W7V A;  4RGZ 1;  2BWY A;  1M35 A;  1XGM A;  3IU7 A;  2GG0 A;  1R58 A;  2BHD A;  4U73 A;  1JAW A;  1XGS A;  5E5B A;  5FCF A;  4IEC A;  5JI6 A;  3BIT A;  3Q6D A;  4U76 A;  1WY2 A;  2MAT A;  1QZY A;  2EA2 A;  4FLL A;  3IU9 A;  3RVA A;  2BN7 A;  1WBQ A;  2V3Z A;  5CDL A;  1N51 A;  1C22 A;  2EVC A;  2BH3 A;  1B59 A;  5FCH A;  1YW7 A;  3FMR A;  2Q8K A;  1PV9 A;  2EVO A;  4U69 A;  1KQ9 A;  2BWV A;  3OOO A;  3FM3 A;  2GU5 A;  3CB5 A;  4IKU A;  2BB7 A;  2P98 A;  4ZWU A;  2GTX A;  3I7M A;  4U75 A;  1BN5 A;  2GG2 A;  4S2T P;  2DFI A;  3ROR A;  4U6J A;  3PN9 A;  4U70 A;  4S01 A;  2G6P A;  2BWS A;  2BWX A;  4ZNG A;  5CNX A;  5CIK A;  3S6B A;  2V3Y A;  4PV4 A;  2GG5 A;  2Q94 A;  4FLK A;  4IKS A;  5D6F A;  2GU7 A;  4RZZ A;  1WL9 A;  1BOA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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