3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
1XGOA 1PV9A 1C23A 1WY2A 2DFIA 1M35A 4IPAA 2BHAA 1C24A 2GZ5A 1XGNA 2ZSGA 1B59A 4S2TP 3FMQA 4IF7A 1QXWA 1YVMA 1MATA 3RORA 1R5HA 1YW9A 2IW2A 4Z7MA 5FCFA 2BB7A 3L7GA 1QXYA 1QZYA 2GG3A 2V3XA 3CB6A 5CDVA 3FM3A 4S2RP 1YJ3A 4FLJA 3MATA 1KP0A 1W2MA 1WL6A 2B3HA 3BIPA 4RGZ1 4B28A 2GGBA 1XGMA 2B3KA 1B6AA 4FLIA 1R58A 1WN1A 5D6EA 1N51A 2GG8A 3Q6DA 4FLKA 4S01A 3L24A 1KQ0A 1R5GA 1C21A 3IU7A 1JAWA 3PKBA 4QR8A 2P98A 2EVCA 3BITA 2EA2A 4U76A 2Q8KA 2GU7A 5FCHA 3CB5A 2BN7A 3TAVA 2Q92A 3FMRA 3PKEA 4IKTA 4IKSA 4U73A 4ZWPA 4IDYA 2GG0A 2GU4A 2BHDA 4IKRA 3IU9A 2EVOA 2V3ZA 2GU6A 1O0XA 2MATA 5JI6A 2GGCA 1YW7A 3CTZA 3IU8A 5CNXA 2GG7A 1BN5A 1XNZA 4U70A 4FO8A 4S00A 2V3YA 2Q94A 2BWUA 4U6CA 3RVAA 2BWSA 3PKDA 4A6WA 4RZYA 2B3LA 1XGSA 1W7VA 4U71A 4EGEA 4U6ZA 1Y1NA 4HXXA 2NQ6A 5CIKA 5CDLA 4MATA 3S6BA 1YW8A 4KM3A 1QXZA 2GG5A 2HOWA 2GU5A 4U1BA 5JFRA 2BWXA 2NQ7A 2Q95A 4IU6A 2V6CA 3MX6A 2GTXA 4U6WA 5E5BA 2GA2A 2BHCA 4OOKA 1WLRA 4PNCA 1A16A 5JHUA 4R60A 4ZWUA 4IKUA 3BIQA 3PKCA 4IECA 4FLLA 1WBQA 4A6VA 4JUQA 5CDEA 2BH3A 1CHMA 1WL9A 2GG2A 3TB5A 2BWWA 4FKCA 5CE6A 3D27A 3MR1A 4FO7A 4RZZA 2BWVA 2G6PA 2P99A 3PKAA 4U6EA 1BOAA 3IG4A 4FUKA 2OAZA 2BHBA 4ZNGA 4U75A 2BWTA 4U69A 2Q96A 4U6JA 2EA4A 1KQ9A 2ADUA 1C27A 2EVMA 2OKNA 2BWYA 4PV4A 5CLSA 2GG9A 5D6FA 4ZWOA 2P9AA 1C22A 2Q93A 1WKMA
chains in the Genus database with same CATH superfamily
1XGOA 1PV9A 1C23A 1WY2A 2DFIA 1M35A 4IPAA 2BHAA 1C24A 2GZ5A 1XGNA 2ZSGA 1B59A 4S2TP 3FMQA 4IF7A 1QXWA 1YVMA 1MATA 3RORA 1R5HA 1YW9A 2IW2A 4Z7MA 5FCFA 2BB7A 3L7GA 1QXYA 1QZYA 2GG3A 2V3XA 3CB6A 5CDVA 3FM3A 4S2RP 1YJ3A 4FLJA 3MATA 1KP0A 1W2MA 1WL6A 2B3HA 3BIPA 4RGZ1 4B28A 2GGBA 1XGMA 2B3KA 1B6AA 4FLIA 1R58A 1WN1A 5D6EA 1N51A 2GG8A 3Q6DA 4FLKA 4S01A 3L24A 1KQ0A 1R5GA 1C21A 3IU7A 1JAWA 3PKBA 4QR8A 2P98A 2EVCA 3BITA 2EA2A 4U76A 2Q8KA 2GU7A 5FCHA 3CB5A 2BN7A 3TAVA 2Q92A 3FMRA 3PKEA 4IKTA 4IKSA 4U73A 4ZWPA 4IDYA 2GG0A 2GU4A 2BHDA 4IKRA 3IU9A 2EVOA 2V3ZA 2GU6A 1O0XA 2MATA 5JI6A 2GGCA 1YW7A 3CTZA 3IU8A 5CNXA 2GG7A 1BN5A 1XNZA 4U70A 4FO8A 4S00A 2V3YA 2Q94A 2BWUA 4U6CA 3RVAA 2BWSA 3PKDA 4A6WA 4RZYA 2B3LA 1XGSA 1W7VA 4U71A 4EGEA 4U6ZA 1Y1NA 4HXXA 2NQ6A 5CIKA 5CDLA 4MATA 3S6BA 1YW8A 4KM3A 1QXZA 2GG5A 2HOWA 2GU5A 4U1BA 5JFRA 2BWXA 2NQ7A 2Q95A 4IU6A 2V6CA 3MX6A 2GTXA 4U6WA 5E5BA 2GA2A 2BHCA 4OOKA 1WLRA 4PNCA 1A16A 5JHUA 4R60A 4ZWUA 4IKUA 3BIQA 3PKCA 4IECA 4FLLA 1WBQA 4A6VA 4JUQA 5CDEA 2BH3A 1CHMA 1WL9A 2GG2A 3TB5A 2BWWA 4FKCA 5CE6A 3D27A 3MR1A 4FO7A 4RZZA 2BWVA 2G6PA 2P99A 3PKAA 4U6EA 1BOAA 3IG4A 4FUKA 2OAZA 2BHBA 4ZNGA 4U75A 2BWTA 4U69A 2Q96A 4U6JA 2EA4A 1KQ9A 2ADUA 1C27A 2EVMA 2OKNA 2BWYA 4PV4A 5CLSA 2GG9A 5D6FA 4ZWOA 2P9AA 1C22A 2Q93A 1WKMA
chains in the Genus database with same CATH topology
1XGOA 1PV9A 1C23A 1WY2A 2DFIA 1M35A 4IPAA 2BHAA 1C24A 2GZ5A 1XGNA 2ZSGA 1B59A 4S2TP 3FMQA 4IF7A 1QXWA 1YVMA 1MATA 3RORA 1R5HA 1YW9A 2IW2A 4Z7MA 5FCFA 2BB7A 3L7GA 1QXYA 1QZYA 2GG3A 2V3XA 3CB6A 5CDVA 3FM3A 4S2RP 1YJ3A 4FLJA 3MATA 1KP0A 1W2MA 1WL6A 2B3HA 3BIPA 4RGZ1 4B28A 2GGBA 1XGMA 2B3KA 1B6AA 4FLIA 1R58A 1WN1A 5D6EA 1N51A 2GG8A 3Q6DA 4FLKA 4S01A 3L24A 1KQ0A 1R5GA 1C21A 3IU7A 1JAWA 3PKBA 4QR8A 2P98A 2EVCA 3BITA 2EA2A 4U76A 2Q8KA 2GU7A 5FCHA 3CB5A 2BN7A 3TAVA 2Q92A 3FMRA 3PKEA 4IKTA 4IKSA 4U73A 4ZWPA 4IDYA 2GG0A 2GU4A 2BHDA 4IKRA 3IU9A 2EVOA 2V3ZA 2GU6A 1O0XA 2MATA 5JI6A 2GGCA 1YW7A 3CTZA 3IU8A 5CNXA 2GG7A 1BN5A 1XNZA 4U70A 4FO8A 4S00A 2V3YA 2Q94A 2BWUA 4U6CA 3RVAA 2BWSA 3PKDA 4A6WA 4RZYA 2B3LA 1XGSA 1W7VA 4U71A 4EGEA 4U6ZA 1Y1NA 4HXXA 2NQ6A 5CIKA 5CDLA 4MATA 3S6BA 1YW8A 4KM3A 1QXZA 2GG5A 2HOWA 2GU5A 4U1BA 5JFRA 2BWXA 2NQ7A 2Q95A 4IU6A 2V6CA 3MX6A 2GTXA 4U6WA 5E5BA 2GA2A 2BHCA 4OOKA 1WLRA 4PNCA 1A16A 5JHUA 4R60A 4ZWUA 4IKUA 3BIQA 3PKCA 4IECA 4FLLA 1WBQA 4A6VA 4JUQA 5CDEA 2BH3A 1CHMA 1WL9A 2GG2A 3TB5A 2BWWA 4FKCA 5CE6A 3D27A 3MR1A 4FO7A 4RZZA 2BWVA 2G6PA 2P99A 3PKAA 4U6EA 1BOAA 3IG4A 4FUKA 2OAZA 2BHBA 4ZNGA 4U75A 2BWTA 4U69A 2Q96A 4U6JA 2EA4A 1KQ9A 2ADUA 1C27A 2EVMA 2OKNA 2BWYA 4PV4A 5CLSA 2GG9A 5D6FA 4ZWOA 2P9AA 1C22A 2Q93A 1WKMA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1XGO A;  1PV9 A;  1C23 A;  1WY2 A;  2DFI A;  1M35 A;  4IPA A;  2BHA A;  1C24 A;  2GZ5 A;  1XGN A;  2ZSG A;  1B59 A;  4S2T P;  3FMQ A;  4IF7 A;  1QXW A;  1YVM A;  1MAT A;  3ROR A;  1R5H A;  1YW9 A;  2IW2 A;  4Z7M A;  5FCF A;  2BB7 A;  3L7G A;  1QXY A;  1QZY A;  2GG3 A;  2V3X A;  3CB6 A;  5CDV A;  3FM3 A;  4S2R P;  1YJ3 A;  4FLJ A;  3MAT A;  1KP0 A;  1W2M A;  1WL6 A;  2B3H A;  3BIP A;  4RGZ 1;  4B28 A;  2GGB A;  1XGM A;  2B3K A;  1B6A A;  4FLI A;  1R58 A;  1WN1 A;  5D6E A;  1N51 A;  2GG8 A;  3Q6D A;  4FLK A;  4S01 A;  3L24 A;  1KQ0 A;  1R5G A;  1C21 A;  3IU7 A;  1JAW A;  3PKB A;  4QR8 A;  2P98 A;  2EVC A;  3BIT A;  2EA2 A;  4U76 A;  2Q8K A;  2GU7 A;  5FCH A;  3CB5 A;  2BN7 A;  3TAV A;  2Q92 A;  3FMR A;  3PKE A;  4IKT A;  4IKS A;  4U73 A;  4ZWP A;  4IDY A;  2GG0 A;  2GU4 A;  2BHD A;  4IKR A;  3IU9 A;  2EVO A;  2V3Z A;  2GU6 A;  1O0X A;  2MAT A;  5JI6 A;  2GGC A;  1YW7 A;  3CTZ A;  3IU8 A;  5CNX A;  2GG7 A;  1BN5 A;  1XNZ A;  4U70 A;  4FO8 A;  4S00 A;  2V3Y A;  2Q94 A;  2BWU A;  4U6C A;  3RVA A;  2BWS A;  3PKD A;  4A6W A;  4RZY A;  2B3L A;  1XGS A;  1W7V A;  4U71 A;  4EGE A;  4U6Z A;  1Y1N A;  4HXX A;  2NQ6 A;  5CIK A;  5CDL A;  4MAT A;  3S6B A;  1YW8 A;  4KM3 A;  1QXZ A;  2GG5 A;  2HOW A;  2GU5 A;  4U1B A;  5JFR A;  2BWX A;  2NQ7 A;  2Q95 A;  4IU6 A;  2V6C A;  3MX6 A;  2GTX A;  4U6W A;  5E5B A;  2GA2 A;  2BHC A;  4OOK A;  1WLR A;  4PNC A;  1A16 A;  5JHU A;  4R60 A;  4ZWU A;  4IKU A;  3BIQ A;  3PKC A;  4IEC A;  4FLL A;  1WBQ A;  4A6V A;  4JUQ A;  5CDE A;  2BH3 A;  1CHM A;  1WL9 A;  2GG2 A;  3TB5 A;  2BWW A;  4FKC A;  5CE6 A;  3D27 A;  3MR1 A;  4FO7 A;  4RZZ A;  2BWV A;  2G6P A;  2P99 A;  3PKA A;  4U6E A;  1BOA A;  3IG4 A;  4FUK A;  2OAZ A;  2BHB A;  4ZNG A;  4U75 A;  2BWT A;  4U69 A;  2Q96 A;  4U6J A;  2EA4 A;  1KQ9 A;  2ADU A;  1C27 A;  2EVM A;  2OKN A;  2BWY A;  4PV4 A;  5CLS A;  2GG9 A;  5D6F A;  4ZWO A;  2P9A A;  1C22 A;  2Q93 A;  1WKM A; 
#chains in the Genus database with same CATH topology
 1XGO A;  1PV9 A;  1C23 A;  1WY2 A;  2DFI A;  1M35 A;  4IPA A;  2BHA A;  1C24 A;  2GZ5 A;  1XGN A;  2ZSG A;  1B59 A;  4S2T P;  3FMQ A;  4IF7 A;  1QXW A;  1YVM A;  1MAT A;  3ROR A;  1R5H A;  1YW9 A;  2IW2 A;  4Z7M A;  5FCF A;  2BB7 A;  3L7G A;  1QXY A;  1QZY A;  2GG3 A;  2V3X A;  3CB6 A;  5CDV A;  3FM3 A;  4S2R P;  1YJ3 A;  4FLJ A;  3MAT A;  1KP0 A;  1W2M A;  1WL6 A;  2B3H A;  3BIP A;  4RGZ 1;  4B28 A;  2GGB A;  1XGM A;  2B3K A;  1B6A A;  4FLI A;  1R58 A;  1WN1 A;  5D6E A;  1N51 A;  2GG8 A;  3Q6D A;  4FLK A;  4S01 A;  3L24 A;  1KQ0 A;  1R5G A;  1C21 A;  3IU7 A;  1JAW A;  3PKB A;  4QR8 A;  2P98 A;  2EVC A;  3BIT A;  2EA2 A;  4U76 A;  2Q8K A;  2GU7 A;  5FCH A;  3CB5 A;  2BN7 A;  3TAV A;  2Q92 A;  3FMR A;  3PKE A;  4IKT A;  4IKS A;  4U73 A;  4ZWP A;  4IDY A;  2GG0 A;  2GU4 A;  2BHD A;  4IKR A;  3IU9 A;  2EVO A;  2V3Z A;  2GU6 A;  1O0X A;  2MAT A;  5JI6 A;  2GGC A;  1YW7 A;  3CTZ A;  3IU8 A;  5CNX A;  2GG7 A;  1BN5 A;  1XNZ A;  4U70 A;  4FO8 A;  4S00 A;  2V3Y A;  2Q94 A;  2BWU A;  4U6C A;  3RVA A;  2BWS A;  3PKD A;  4A6W A;  4RZY A;  2B3L A;  1XGS A;  1W7V A;  4U71 A;  4EGE A;  4U6Z A;  1Y1N A;  4HXX A;  2NQ6 A;  5CIK A;  5CDL A;  4MAT A;  3S6B A;  1YW8 A;  4KM3 A;  1QXZ A;  2GG5 A;  2HOW A;  2GU5 A;  4U1B A;  5JFR A;  2BWX A;  2NQ7 A;  2Q95 A;  4IU6 A;  2V6C A;  3MX6 A;  2GTX A;  4U6W A;  5E5B A;  2GA2 A;  2BHC A;  4OOK A;  1WLR A;  4PNC A;  1A16 A;  5JHU A;  4R60 A;  4ZWU A;  4IKU A;  3BIQ A;  3PKC A;  4IEC A;  4FLL A;  1WBQ A;  4A6V A;  4JUQ A;  5CDE A;  2BH3 A;  1CHM A;  1WL9 A;  2GG2 A;  3TB5 A;  2BWW A;  4FKC A;  5CE6 A;  3D27 A;  3MR1 A;  4FO7 A;  4RZZ A;  2BWV A;  2G6P A;  2P99 A;  3PKA A;  4U6E A;  1BOA A;  3IG4 A;  4FUK A;  2OAZ A;  2BHB A;  4ZNG A;  4U75 A;  2BWT A;  4U69 A;  2Q96 A;  4U6J A;  2EA4 A;  1KQ9 A;  2ADU A;  1C27 A;  2EVM A;  2OKN A;  2BWY A;  4PV4 A;  5CLS A;  2GG9 A;  5D6F A;  4ZWO A;  2P9A A;  1C22 A;  2Q93 A;  1WKM A; 
#chains in the Genus database with same CATH homology
 1XGO A;  1PV9 A;  1C23 A;  1WY2 A;  2DFI A;  1M35 A;  4IPA A;  2BHA A;  1C24 A;  2GZ5 A;  1XGN A;  2ZSG A;  1B59 A;  4S2T P;  3FMQ A;  4IF7 A;  1QXW A;  1YVM A;  1MAT A;  3ROR A;  1R5H A;  1YW9 A;  2IW2 A;  4Z7M A;  5FCF A;  2BB7 A;  3L7G A;  1QXY A;  1QZY A;  2GG3 A;  2V3X A;  3CB6 A;  5CDV A;  3FM3 A;  4S2R P;  1YJ3 A;  4FLJ A;  3MAT A;  1KP0 A;  1W2M A;  1WL6 A;  2B3H A;  3BIP A;  4RGZ 1;  4B28 A;  2GGB A;  1XGM A;  2B3K A;  1B6A A;  4FLI A;  1R58 A;  1WN1 A;  5D6E A;  1N51 A;  2GG8 A;  3Q6D A;  4FLK A;  4S01 A;  3L24 A;  1KQ0 A;  1R5G A;  1C21 A;  3IU7 A;  1JAW A;  3PKB A;  4QR8 A;  2P98 A;  2EVC A;  3BIT A;  2EA2 A;  4U76 A;  2Q8K A;  2GU7 A;  5FCH A;  3CB5 A;  2BN7 A;  3TAV A;  2Q92 A;  3FMR A;  3PKE A;  4IKT A;  4IKS A;  4U73 A;  4ZWP A;  4IDY A;  2GG0 A;  2GU4 A;  2BHD A;  4IKR A;  3IU9 A;  2EVO A;  2V3Z A;  2GU6 A;  1O0X A;  2MAT A;  5JI6 A;  2GGC A;  1YW7 A;  3CTZ A;  3IU8 A;  5CNX A;  2GG7 A;  1BN5 A;  1XNZ A;  4U70 A;  4FO8 A;  4S00 A;  2V3Y A;  2Q94 A;  2BWU A;  4U6C A;  3RVA A;  2BWS A;  3PKD A;  4A6W A;  4RZY A;  2B3L A;  1XGS A;  1W7V A;  4U71 A;  4EGE A;  4U6Z A;  1Y1N A;  4HXX A;  2NQ6 A;  5CIK A;  5CDL A;  4MAT A;  3S6B A;  1YW8 A;  4KM3 A;  1QXZ A;  2GG5 A;  2HOW A;  2GU5 A;  4U1B A;  5JFR A;  2BWX A;  2NQ7 A;  2Q95 A;  4IU6 A;  2V6C A;  3MX6 A;  2GTX A;  4U6W A;  5E5B A;  2GA2 A;  2BHC A;  4OOK A;  1WLR A;  4PNC A;  1A16 A;  5JHU A;  4R60 A;  4ZWU A;  4IKU A;  3BIQ A;  3PKC A;  4IEC A;  4FLL A;  1WBQ A;  4A6V A;  4JUQ A;  5CDE A;  2BH3 A;  1CHM A;  1WL9 A;  2GG2 A;  3TB5 A;  2BWW A;  4FKC A;  5CE6 A;  3D27 A;  3MR1 A;  4FO7 A;  4RZZ A;  2BWV A;  2G6P A;  2P99 A;  3PKA A;  4U6E A;  1BOA A;  3IG4 A;  4FUK A;  2OAZ A;  2BHB A;  4ZNG A;  4U75 A;  2BWT A;  4U69 A;  2Q96 A;  4U6J A;  2EA4 A;  1KQ9 A;  2ADU A;  1C27 A;  2EVM A;  2OKN A;  2BWY A;  4PV4 A;  5CLS A;  2GG9 A;  5D6F A;  4ZWO A;  2P9A A;  1C22 A;  2Q93 A;  1WKM A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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