3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
2DFIA 2P99A 2GTXA 4S2TP 1C24A 1B6AA 1CHMA 4IECA 4ZWPA 2BWVA 3RVAA 1YW9A 1C21A 2BHBA 2EVCA 3MX6A 1KQ0A 1YJ3A 1YVMA 2GG9A 1C27A 2BHAA 4R60A 4A6WA 2EVOA 4S01A 1MATA 4U6JA 1WL9A 4ZWOA 3TAVA 1QXYA 2BWYA 2GA2A 2GU6A 1WY2A 2OKNA 4FLIA 4QR8A 4S00A 2ADUA 4U69A 4U73A 2BHDA 2GG3A 3PKDA 2BWUA 2GG5A 2GU4A 2P98A 4U75A 3FMRA 1C23A 2EVMA 4FLKA 2V6CA 1O0XA 2HOWA 4HXXA 4U6WA 1XNZA 2BH3A 2Q92A 4PNCA 3IU7A 5CDVA 3FM3A 1R5GA 2GU7A 3PKAA 4IPAA 4OOKA 4JUQA 2Q95A 3D27A 3S6BA 2GG7A 2GU5A 2BHCA 1XGNA 1A16A 4U76A 5D6FA 4U70A 2BB7A 5CDLA 4PV4A 1W2MA 3IU9A 1XGMA 2NQ6A 4S2RP 4ZWUA 5JI6A 2MATA 5JFRA 2V3YA 1JAWA 2Q8KA 1WBQA 4FLJA 3BITA 1QZYA 2EA4A 2Q94A 2BWXA 4IU6A 1QXZA 2Q93A 3MR1A 4U6CA 2G6PA 4U6EA 4ZNGA 4EGEA 2BWSA 3CB5A 4FLLA 4MATA 4IKTA 1YW7A 2NQ7A 3FMQA 5JHUA 1N51A 2GGBA 1C22A 2BN7A 1YW8A 4IDYA 3RORA 2BWWA 1BOAA 3TB5A 2B3KA 3CB6A 1W7VA 4KM3A 2GGCA 2BWTA 2GG8A 2EA2A 2OAZA 2IW2A 1QXWA 4FO8A 1WN1A 2ZSGA 3MATA 1XGSA 2B3HA 3PKCA 1WLRA 4IF7A 4IKUA 4RZYA 3CTZA 4IKSA 2P9AA 4IKRA 4U1BA 4FKCA 1Y1NA 2GZ5A 3IG4A 3L24A 3L7GA 4A6VA 5CDEA 2Q96A 4RZZA 3PKBA 1BN5A 3BIPA 3IU8A 2V3XA 5FCHA 1PV9A 1R5HA 4U6ZA 5E5BA 5FCFA 4FO7A 4FUKA 4B28A 1M35A 5CLSA 2B3LA 1WL6A 5CIKA 1XGOA 1R58A 2GG2A 3Q6DA 1KP0A 5CE6A 5D6EA 1WKMA 4U71A 4RGZ1 4Z7MA 5CNXA 2GG0A 1B59A 2V3ZA 3PKEA 1KQ9A 3BIQA
chains in the Genus database with same CATH superfamily
2DFIA 2P99A 2GTXA 4S2TP 1C24A 1B6AA 1CHMA 4IECA 4ZWPA 2BWVA 3RVAA 1YW9A 1C21A 2BHBA 2EVCA 3MX6A 1KQ0A 1YJ3A 1YVMA 2GG9A 1C27A 2BHAA 4R60A 4A6WA 2EVOA 4S01A 1MATA 4U6JA 1WL9A 4ZWOA 3TAVA 1QXYA 2BWYA 2GA2A 2GU6A 1WY2A 2OKNA 4FLIA 4QR8A 4S00A 2ADUA 4U69A 4U73A 2BHDA 2GG3A 3PKDA 2BWUA 2GG5A 2GU4A 2P98A 4U75A 3FMRA 1C23A 2EVMA 4FLKA 2V6CA 1O0XA 2HOWA 4HXXA 4U6WA 1XNZA 2BH3A 2Q92A 4PNCA 3IU7A 5CDVA 3FM3A 1R5GA 2GU7A 3PKAA 4IPAA 4OOKA 4JUQA 2Q95A 3D27A 3S6BA 2GG7A 2GU5A 2BHCA 1XGNA 1A16A 4U76A 5D6FA 4U70A 2BB7A 5CDLA 4PV4A 1W2MA 3IU9A 1XGMA 2NQ6A 4S2RP 4ZWUA 5JI6A 2MATA 5JFRA 2V3YA 1JAWA 2Q8KA 1WBQA 4FLJA 3BITA 1QZYA 2EA4A 2Q94A 2BWXA 4IU6A 1QXZA 2Q93A 3MR1A 4U6CA 2G6PA 4U6EA 4ZNGA 4EGEA 2BWSA 3CB5A 4FLLA 4MATA 4IKTA 1YW7A 2NQ7A 3FMQA 5JHUA 1N51A 2GGBA 1C22A 2BN7A 1YW8A 4IDYA 3RORA 2BWWA 1BOAA 3TB5A 2B3KA 3CB6A 1W7VA 4KM3A 2GGCA 2BWTA 2GG8A 2EA2A 2OAZA 2IW2A 1QXWA 4FO8A 1WN1A 2ZSGA 3MATA 1XGSA 2B3HA 3PKCA 1WLRA 4IF7A 4IKUA 4RZYA 3CTZA 4IKSA 2P9AA 4IKRA 4U1BA 4FKCA 1Y1NA 2GZ5A 3IG4A 3L24A 3L7GA 4A6VA 5CDEA 2Q96A 4RZZA 3PKBA 1BN5A 3BIPA 3IU8A 2V3XA 5FCHA 1PV9A 1R5HA 4U6ZA 5E5BA 5FCFA 4FO7A 4FUKA 4B28A 1M35A 5CLSA 2B3LA 1WL6A 5CIKA 1XGOA 1R58A 2GG2A 3Q6DA 1KP0A 5CE6A 5D6EA 1WKMA 4U71A 4RGZ1 4Z7MA 5CNXA 2GG0A 1B59A 2V3ZA 3PKEA 1KQ9A 3BIQA
chains in the Genus database with same CATH topology
2DFIA 2P99A 2GTXA 4S2TP 1C24A 1B6AA 1CHMA 4IECA 4ZWPA 2BWVA 3RVAA 1YW9A 1C21A 2BHBA 2EVCA 3MX6A 1KQ0A 1YJ3A 1YVMA 2GG9A 1C27A 2BHAA 4R60A 4A6WA 2EVOA 4S01A 1MATA 4U6JA 1WL9A 4ZWOA 3TAVA 1QXYA 2BWYA 2GA2A 2GU6A 1WY2A 2OKNA 4FLIA 4QR8A 4S00A 2ADUA 4U69A 4U73A 2BHDA 2GG3A 3PKDA 2BWUA 2GG5A 2GU4A 2P98A 4U75A 3FMRA 1C23A 2EVMA 4FLKA 2V6CA 1O0XA 2HOWA 4HXXA 4U6WA 1XNZA 2BH3A 2Q92A 4PNCA 3IU7A 5CDVA 3FM3A 1R5GA 2GU7A 3PKAA 4IPAA 4OOKA 4JUQA 2Q95A 3D27A 3S6BA 2GG7A 2GU5A 2BHCA 1XGNA 1A16A 4U76A 5D6FA 4U70A 2BB7A 5CDLA 4PV4A 1W2MA 3IU9A 1XGMA 2NQ6A 4S2RP 4ZWUA 5JI6A 2MATA 5JFRA 2V3YA 1JAWA 2Q8KA 1WBQA 4FLJA 3BITA 1QZYA 2EA4A 2Q94A 2BWXA 4IU6A 1QXZA 2Q93A 3MR1A 4U6CA 2G6PA 4U6EA 4ZNGA 4EGEA 2BWSA 3CB5A 4FLLA 4MATA 4IKTA 1YW7A 2NQ7A 3FMQA 5JHUA 1N51A 2GGBA 1C22A 2BN7A 1YW8A 4IDYA 3RORA 2BWWA 1BOAA 3TB5A 2B3KA 3CB6A 1W7VA 4KM3A 2GGCA 2BWTA 2GG8A 2EA2A 2OAZA 2IW2A 1QXWA 4FO8A 1WN1A 2ZSGA 3MATA 1XGSA 2B3HA 3PKCA 1WLRA 4IF7A 4IKUA 4RZYA 3CTZA 4IKSA 2P9AA 4IKRA 4U1BA 4FKCA 1Y1NA 2GZ5A 3IG4A 3L24A 3L7GA 4A6VA 5CDEA 2Q96A 4RZZA 3PKBA 1BN5A 3BIPA 3IU8A 2V3XA 5FCHA 1PV9A 1R5HA 4U6ZA 5E5BA 5FCFA 4FO7A 4FUKA 4B28A 1M35A 5CLSA 2B3LA 1WL6A 5CIKA 1XGOA 1R58A 2GG2A 3Q6DA 1KP0A 5CE6A 5D6EA 1WKMA 4U71A 4RGZ1 4Z7MA 5CNXA 2GG0A 1B59A 2V3ZA 3PKEA 1KQ9A 3BIQA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2DFI A;  2P99 A;  2GTX A;  4S2T P;  1C24 A;  1B6A A;  1CHM A;  4IEC A;  4ZWP A;  2BWV A;  3RVA A;  1YW9 A;  1C21 A;  2BHB A;  2EVC A;  3MX6 A;  1KQ0 A;  1YJ3 A;  1YVM A;  2GG9 A;  1C27 A;  2BHA A;  4R60 A;  4A6W A;  2EVO A;  4S01 A;  1MAT A;  4U6J A;  1WL9 A;  4ZWO A;  3TAV A;  1QXY A;  2BWY A;  2GA2 A;  2GU6 A;  1WY2 A;  2OKN A;  4FLI A;  4QR8 A;  4S00 A;  2ADU A;  4U69 A;  4U73 A;  2BHD A;  2GG3 A;  3PKD A;  2BWU A;  2GG5 A;  2GU4 A;  2P98 A;  4U75 A;  3FMR A;  1C23 A;  2EVM A;  4FLK A;  2V6C A;  1O0X A;  2HOW A;  4HXX A;  4U6W A;  1XNZ A;  2BH3 A;  2Q92 A;  4PNC A;  3IU7 A;  5CDV A;  3FM3 A;  1R5G A;  2GU7 A;  3PKA A;  4IPA A;  4OOK A;  4JUQ A;  2Q95 A;  3D27 A;  3S6B A;  2GG7 A;  2GU5 A;  2BHC A;  1XGN A;  1A16 A;  4U76 A;  5D6F A;  4U70 A;  2BB7 A;  5CDL A;  4PV4 A;  1W2M A;  3IU9 A;  1XGM A;  2NQ6 A;  4S2R P;  4ZWU A;  5JI6 A;  2MAT A;  5JFR A;  2V3Y A;  1JAW A;  2Q8K A;  1WBQ A;  4FLJ A;  3BIT A;  1QZY A;  2EA4 A;  2Q94 A;  2BWX A;  4IU6 A;  1QXZ A;  2Q93 A;  3MR1 A;  4U6C A;  2G6P A;  4U6E A;  4ZNG A;  4EGE A;  2BWS A;  3CB5 A;  4FLL A;  4MAT A;  4IKT A;  1YW7 A;  2NQ7 A;  3FMQ A;  5JHU A;  1N51 A;  2GGB A;  1C22 A;  2BN7 A;  1YW8 A;  4IDY A;  3ROR A;  2BWW A;  1BOA A;  3TB5 A;  2B3K A;  3CB6 A;  1W7V A;  4KM3 A;  2GGC A;  2BWT A;  2GG8 A;  2EA2 A;  2OAZ A;  2IW2 A;  1QXW A;  4FO8 A;  1WN1 A;  2ZSG A;  3MAT A;  1XGS A;  2B3H A;  3PKC A;  1WLR A;  4IF7 A;  4IKU A;  4RZY A;  3CTZ A;  4IKS A;  2P9A A;  4IKR A;  4U1B A;  4FKC A;  1Y1N A;  2GZ5 A;  3IG4 A;  3L24 A;  3L7G A;  4A6V A;  5CDE A;  2Q96 A;  4RZZ A;  3PKB A;  1BN5 A;  3BIP A;  3IU8 A;  2V3X A;  5FCH A;  1PV9 A;  1R5H A;  4U6Z A;  5E5B A;  5FCF A;  4FO7 A;  4FUK A;  4B28 A;  1M35 A;  5CLS A;  2B3L A;  1WL6 A;  5CIK A;  1XGO A;  1R58 A;  2GG2 A;  3Q6D A;  1KP0 A;  5CE6 A;  5D6E A;  1WKM A;  4U71 A;  4RGZ 1;  4Z7M A;  5CNX A;  2GG0 A;  1B59 A;  2V3Z A;  3PKE A;  1KQ9 A;  3BIQ A; 
#chains in the Genus database with same CATH topology
 2DFI A;  2P99 A;  2GTX A;  4S2T P;  1C24 A;  1B6A A;  1CHM A;  4IEC A;  4ZWP A;  2BWV A;  3RVA A;  1YW9 A;  1C21 A;  2BHB A;  2EVC A;  3MX6 A;  1KQ0 A;  1YJ3 A;  1YVM A;  2GG9 A;  1C27 A;  2BHA A;  4R60 A;  4A6W A;  2EVO A;  4S01 A;  1MAT A;  4U6J A;  1WL9 A;  4ZWO A;  3TAV A;  1QXY A;  2BWY A;  2GA2 A;  2GU6 A;  1WY2 A;  2OKN A;  4FLI A;  4QR8 A;  4S00 A;  2ADU A;  4U69 A;  4U73 A;  2BHD A;  2GG3 A;  3PKD A;  2BWU A;  2GG5 A;  2GU4 A;  2P98 A;  4U75 A;  3FMR A;  1C23 A;  2EVM A;  4FLK A;  2V6C A;  1O0X A;  2HOW A;  4HXX A;  4U6W A;  1XNZ A;  2BH3 A;  2Q92 A;  4PNC A;  3IU7 A;  5CDV A;  3FM3 A;  1R5G A;  2GU7 A;  3PKA A;  4IPA A;  4OOK A;  4JUQ A;  2Q95 A;  3D27 A;  3S6B A;  2GG7 A;  2GU5 A;  2BHC A;  1XGN A;  1A16 A;  4U76 A;  5D6F A;  4U70 A;  2BB7 A;  5CDL A;  4PV4 A;  1W2M A;  3IU9 A;  1XGM A;  2NQ6 A;  4S2R P;  4ZWU A;  5JI6 A;  2MAT A;  5JFR A;  2V3Y A;  1JAW A;  2Q8K A;  1WBQ A;  4FLJ A;  3BIT A;  1QZY A;  2EA4 A;  2Q94 A;  2BWX A;  4IU6 A;  1QXZ A;  2Q93 A;  3MR1 A;  4U6C A;  2G6P A;  4U6E A;  4ZNG A;  4EGE A;  2BWS A;  3CB5 A;  4FLL A;  4MAT A;  4IKT A;  1YW7 A;  2NQ7 A;  3FMQ A;  5JHU A;  1N51 A;  2GGB A;  1C22 A;  2BN7 A;  1YW8 A;  4IDY A;  3ROR A;  2BWW A;  1BOA A;  3TB5 A;  2B3K A;  3CB6 A;  1W7V A;  4KM3 A;  2GGC A;  2BWT A;  2GG8 A;  2EA2 A;  2OAZ A;  2IW2 A;  1QXW A;  4FO8 A;  1WN1 A;  2ZSG A;  3MAT A;  1XGS A;  2B3H A;  3PKC A;  1WLR A;  4IF7 A;  4IKU A;  4RZY A;  3CTZ A;  4IKS A;  2P9A A;  4IKR A;  4U1B A;  4FKC A;  1Y1N A;  2GZ5 A;  3IG4 A;  3L24 A;  3L7G A;  4A6V A;  5CDE A;  2Q96 A;  4RZZ A;  3PKB A;  1BN5 A;  3BIP A;  3IU8 A;  2V3X A;  5FCH A;  1PV9 A;  1R5H A;  4U6Z A;  5E5B A;  5FCF A;  4FO7 A;  4FUK A;  4B28 A;  1M35 A;  5CLS A;  2B3L A;  1WL6 A;  5CIK A;  1XGO A;  1R58 A;  2GG2 A;  3Q6D A;  1KP0 A;  5CE6 A;  5D6E A;  1WKM A;  4U71 A;  4RGZ 1;  4Z7M A;  5CNX A;  2GG0 A;  1B59 A;  2V3Z A;  3PKE A;  1KQ9 A;  3BIQ A; 
#chains in the Genus database with same CATH homology
 2DFI A;  2P99 A;  2GTX A;  4S2T P;  1C24 A;  1B6A A;  1CHM A;  4IEC A;  4ZWP A;  2BWV A;  3RVA A;  1YW9 A;  1C21 A;  2BHB A;  2EVC A;  3MX6 A;  1KQ0 A;  1YJ3 A;  1YVM A;  2GG9 A;  1C27 A;  2BHA A;  4R60 A;  4A6W A;  2EVO A;  4S01 A;  1MAT A;  4U6J A;  1WL9 A;  4ZWO A;  3TAV A;  1QXY A;  2BWY A;  2GA2 A;  2GU6 A;  1WY2 A;  2OKN A;  4FLI A;  4QR8 A;  4S00 A;  2ADU A;  4U69 A;  4U73 A;  2BHD A;  2GG3 A;  3PKD A;  2BWU A;  2GG5 A;  2GU4 A;  2P98 A;  4U75 A;  3FMR A;  1C23 A;  2EVM A;  4FLK A;  2V6C A;  1O0X A;  2HOW A;  4HXX A;  4U6W A;  1XNZ A;  2BH3 A;  2Q92 A;  4PNC A;  3IU7 A;  5CDV A;  3FM3 A;  1R5G A;  2GU7 A;  3PKA A;  4IPA A;  4OOK A;  4JUQ A;  2Q95 A;  3D27 A;  3S6B A;  2GG7 A;  2GU5 A;  2BHC A;  1XGN A;  1A16 A;  4U76 A;  5D6F A;  4U70 A;  2BB7 A;  5CDL A;  4PV4 A;  1W2M A;  3IU9 A;  1XGM A;  2NQ6 A;  4S2R P;  4ZWU A;  5JI6 A;  2MAT A;  5JFR A;  2V3Y A;  1JAW A;  2Q8K A;  1WBQ A;  4FLJ A;  3BIT A;  1QZY A;  2EA4 A;  2Q94 A;  2BWX A;  4IU6 A;  1QXZ A;  2Q93 A;  3MR1 A;  4U6C A;  2G6P A;  4U6E A;  4ZNG A;  4EGE A;  2BWS A;  3CB5 A;  4FLL A;  4MAT A;  4IKT A;  1YW7 A;  2NQ7 A;  3FMQ A;  5JHU A;  1N51 A;  2GGB A;  1C22 A;  2BN7 A;  1YW8 A;  4IDY A;  3ROR A;  2BWW A;  1BOA A;  3TB5 A;  2B3K A;  3CB6 A;  1W7V A;  4KM3 A;  2GGC A;  2BWT A;  2GG8 A;  2EA2 A;  2OAZ A;  2IW2 A;  1QXW A;  4FO8 A;  1WN1 A;  2ZSG A;  3MAT A;  1XGS A;  2B3H A;  3PKC A;  1WLR A;  4IF7 A;  4IKU A;  4RZY A;  3CTZ A;  4IKS A;  2P9A A;  4IKR A;  4U1B A;  4FKC A;  1Y1N A;  2GZ5 A;  3IG4 A;  3L24 A;  3L7G A;  4A6V A;  5CDE A;  2Q96 A;  4RZZ A;  3PKB A;  1BN5 A;  3BIP A;  3IU8 A;  2V3X A;  5FCH A;  1PV9 A;  1R5H A;  4U6Z A;  5E5B A;  5FCF A;  4FO7 A;  4FUK A;  4B28 A;  1M35 A;  5CLS A;  2B3L A;  1WL6 A;  5CIK A;  1XGO A;  1R58 A;  2GG2 A;  3Q6D A;  1KP0 A;  5CE6 A;  5D6E A;  1WKM A;  4U71 A;  4RGZ 1;  4Z7M A;  5CNX A;  2GG0 A;  1B59 A;  2V3Z A;  3PKE A;  1KQ9 A;  3BIQ A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite