3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
source organism Mycobacterium tuberculosis
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
2BWXA 2GGBA 4FO7A 3CB6A 5CDVA 4B28A 1WBQA 2GU5A 3CB5A 1N51A 4PV4A 1M35A 1YW7A 2BWUA 2BWSA 3MX6A 4U69A 4ZWUA 4U1BA 3RORA 1A16A 1WN1A 2GTXA 4IKSA 2BN7A 2BWYA 4FLIA 2V6CA 2ADUA 5CNXA 5CDLA 4U6JA 2NQ7A 3IU8A 2BHCA 3PKCA 1QZYA 4RZYA 2GG0A 3Q6DA 1R58A 2GG2A 4S01A 2B3LA 1KQ9A 4IECA 2Q8KA 1JAWA 4IU6A 2OAZA 2V3XA 3FMRA 4U6WA 2G6PA 1WKMA 2DFIA 4U76A 3TB5A 4IPAA 2HOWA 1YW9A 1R5HA 3IU7A 1KP0A 2GG8A 4U6ZA 2ZSGA 1WL9A 4IKUA 1C22A 1MATA 5CIKA 3PKAA 2P99A 4S2TP 1W7VA 2Q95A 1CHMA 1XGOA 3PKEA 4FKCA 2GU7A 3FMQA 4EGEA 4JUQA 4ZWOA 3MATA 4U6CA 4FLLA 2GA2A 2BHDA 2GU6A 2BWTA 2BB7A 3FM3A 5D6EA 2Q92A 1XNZA 1XGSA 1QXYA 1W2MA 1XGNA 3L24A 2BWVA 2P98A 1XGMA 2EVCA 5D6FA 1C23A 2EA2A 2Q93A 4U70A 5CE6A 4S2RP 4ZNGA 1B6AA 4KM3A 1YVMA 4OOKA 2GG5A 4MATA 4QR8A 3BITA 5FCFA 1B59A 4R60A 5JHUA 3BIPA 2BWWA 5FCHA 5E5BA 2Q96A 2BHBA 2MATA 3L7GA 3S6BA 1WLRA 4FO8A 1QXZA 2EA4A 2OKNA 3BIQA 4RGZ1 4ZWPA 1O0XA 4A6WA 2BH3A 2Q94A 4IKRA 3PKDA 2V3YA 4PNCA 2EVOA 3IG4A 2GG7A 2B3HA 1BOAA 2GGCA 1YJ3A 4FUKA 4IDYA 2GG3A 2GZ5A 1PV9A 5CLSA 5JFRA 2B3KA 4U73A 4U75A 4FLJA 1WL6A 1WY2A 2IW2A 4U71A 2NQ6A 4A6VA 1C21A 1R5GA 3RVAA 4U6EA 4Z7MA 4FLKA 4IF7A 3D27A 4RZZA 3TAVA 2GU4A 1C24A 1QXWA 1C27A 1KQ0A 2P9AA 2V3ZA 1YW8A 3IU9A 4HXXA 4S00A 2GG9A 3PKBA 2BHAA 1BN5A 3CTZA 5CDEA 3MR1A 5JI6A 2EVMA 4IKTA 1Y1NA
chains in the Genus database with same CATH superfamily
2BWXA 2GGBA 4FO7A 3CB6A 5CDVA 4B28A 1WBQA 2GU5A 3CB5A 1N51A 4PV4A 1M35A 1YW7A 2BWUA 2BWSA 3MX6A 4U69A 4ZWUA 4U1BA 3RORA 1A16A 1WN1A 2GTXA 4IKSA 2BN7A 2BWYA 4FLIA 2V6CA 2ADUA 5CNXA 5CDLA 4U6JA 2NQ7A 3IU8A 2BHCA 3PKCA 1QZYA 4RZYA 2GG0A 3Q6DA 1R58A 2GG2A 4S01A 2B3LA 1KQ9A 4IECA 2Q8KA 1JAWA 4IU6A 2OAZA 2V3XA 3FMRA 4U6WA 2G6PA 1WKMA 2DFIA 4U76A 3TB5A 4IPAA 2HOWA 1YW9A 1R5HA 3IU7A 1KP0A 2GG8A 4U6ZA 2ZSGA 1WL9A 4IKUA 1C22A 1MATA 5CIKA 3PKAA 2P99A 4S2TP 1W7VA 2Q95A 1CHMA 1XGOA 3PKEA 4FKCA 2GU7A 3FMQA 4EGEA 4JUQA 4ZWOA 3MATA 4U6CA 4FLLA 2GA2A 2BHDA 2GU6A 2BWTA 2BB7A 3FM3A 5D6EA 2Q92A 1XNZA 1XGSA 1QXYA 1W2MA 1XGNA 3L24A 2BWVA 2P98A 1XGMA 2EVCA 5D6FA 1C23A 2EA2A 2Q93A 4U70A 5CE6A 4S2RP 4ZNGA 1B6AA 4KM3A 1YVMA 4OOKA 2GG5A 4MATA 4QR8A 3BITA 5FCFA 1B59A 4R60A 5JHUA 3BIPA 2BWWA 5FCHA 5E5BA 2Q96A 2BHBA 2MATA 3L7GA 3S6BA 1WLRA 4FO8A 1QXZA 2EA4A 2OKNA 3BIQA 4RGZ1 4ZWPA 1O0XA 4A6WA 2BH3A 2Q94A 4IKRA 3PKDA 2V3YA 4PNCA 2EVOA 3IG4A 2GG7A 2B3HA 1BOAA 2GGCA 1YJ3A 4FUKA 4IDYA 2GG3A 2GZ5A 1PV9A 5CLSA 5JFRA 2B3KA 4U73A 4U75A 4FLJA 1WL6A 1WY2A 2IW2A 4U71A 2NQ6A 4A6VA 1C21A 1R5GA 3RVAA 4U6EA 4Z7MA 4FLKA 4IF7A 3D27A 4RZZA 3TAVA 2GU4A 1C24A 1QXWA 1C27A 1KQ0A 2P9AA 2V3ZA 1YW8A 3IU9A 4HXXA 4S00A 2GG9A 3PKBA 2BHAA 1BN5A 3CTZA 5CDEA 3MR1A 5JI6A 2EVMA 4IKTA 1Y1NA
chains in the Genus database with same CATH topology
2BWXA 2GGBA 4FO7A 3CB6A 5CDVA 4B28A 1WBQA 2GU5A 3CB5A 1N51A 4PV4A 1M35A 1YW7A 2BWUA 2BWSA 3MX6A 4U69A 4ZWUA 4U1BA 3RORA 1A16A 1WN1A 2GTXA 4IKSA 2BN7A 2BWYA 4FLIA 2V6CA 2ADUA 5CNXA 5CDLA 4U6JA 2NQ7A 3IU8A 2BHCA 3PKCA 1QZYA 4RZYA 2GG0A 3Q6DA 1R58A 2GG2A 4S01A 2B3LA 1KQ9A 4IECA 2Q8KA 1JAWA 4IU6A 2OAZA 2V3XA 3FMRA 4U6WA 2G6PA 1WKMA 2DFIA 4U76A 3TB5A 4IPAA 2HOWA 1YW9A 1R5HA 3IU7A 1KP0A 2GG8A 4U6ZA 2ZSGA 1WL9A 4IKUA 1C22A 1MATA 5CIKA 3PKAA 2P99A 4S2TP 1W7VA 2Q95A 1CHMA 1XGOA 3PKEA 4FKCA 2GU7A 3FMQA 4EGEA 4JUQA 4ZWOA 3MATA 4U6CA 4FLLA 2GA2A 2BHDA 2GU6A 2BWTA 2BB7A 3FM3A 5D6EA 2Q92A 1XNZA 1XGSA 1QXYA 1W2MA 1XGNA 3L24A 2BWVA 2P98A 1XGMA 2EVCA 5D6FA 1C23A 2EA2A 2Q93A 4U70A 5CE6A 4S2RP 4ZNGA 1B6AA 4KM3A 1YVMA 4OOKA 2GG5A 4MATA 4QR8A 3BITA 5FCFA 1B59A 4R60A 5JHUA 3BIPA 2BWWA 5FCHA 5E5BA 2Q96A 2BHBA 2MATA 3L7GA 3S6BA 1WLRA 4FO8A 1QXZA 2EA4A 2OKNA 3BIQA 4RGZ1 4ZWPA 1O0XA 4A6WA 2BH3A 2Q94A 4IKRA 3PKDA 2V3YA 4PNCA 2EVOA 3IG4A 2GG7A 2B3HA 1BOAA 2GGCA 1YJ3A 4FUKA 4IDYA 2GG3A 2GZ5A 1PV9A 5CLSA 5JFRA 2B3KA 4U73A 4U75A 4FLJA 1WL6A 1WY2A 2IW2A 4U71A 2NQ6A 4A6VA 1C21A 1R5GA 3RVAA 4U6EA 4Z7MA 4FLKA 4IF7A 3D27A 4RZZA 3TAVA 2GU4A 1C24A 1QXWA 1C27A 1KQ0A 2P9AA 2V3ZA 1YW8A 3IU9A 4HXXA 4S00A 2GG9A 3PKBA 2BHAA 1BN5A 3CTZA 5CDEA 3MR1A 5JI6A 2EVMA 4IKTA 1Y1NA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2BWX A;  2GGB A;  4FO7 A;  3CB6 A;  5CDV A;  4B28 A;  1WBQ A;  2GU5 A;  3CB5 A;  1N51 A;  4PV4 A;  1M35 A;  1YW7 A;  2BWU A;  2BWS A;  3MX6 A;  4U69 A;  4ZWU A;  4U1B A;  3ROR A;  1A16 A;  1WN1 A;  2GTX A;  4IKS A;  2BN7 A;  2BWY A;  4FLI A;  2V6C A;  2ADU A;  5CNX A;  5CDL A;  4U6J A;  2NQ7 A;  3IU8 A;  2BHC A;  3PKC A;  1QZY A;  4RZY A;  2GG0 A;  3Q6D A;  1R58 A;  2GG2 A;  4S01 A;  2B3L A;  1KQ9 A;  4IEC A;  2Q8K A;  1JAW A;  4IU6 A;  2OAZ A;  2V3X A;  3FMR A;  4U6W A;  2G6P A;  1WKM A;  2DFI A;  4U76 A;  3TB5 A;  4IPA A;  2HOW A;  1YW9 A;  1R5H A;  3IU7 A;  1KP0 A;  2GG8 A;  4U6Z A;  2ZSG A;  1WL9 A;  4IKU A;  1C22 A;  1MAT A;  5CIK A;  3PKA A;  2P99 A;  4S2T P;  1W7V A;  2Q95 A;  1CHM A;  1XGO A;  3PKE A;  4FKC A;  2GU7 A;  3FMQ A;  4EGE A;  4JUQ A;  4ZWO A;  3MAT A;  4U6C A;  4FLL A;  2GA2 A;  2BHD A;  2GU6 A;  2BWT A;  2BB7 A;  3FM3 A;  5D6E A;  2Q92 A;  1XNZ A;  1XGS A;  1QXY A;  1W2M A;  1XGN A;  3L24 A;  2BWV A;  2P98 A;  1XGM A;  2EVC A;  5D6F A;  1C23 A;  2EA2 A;  2Q93 A;  4U70 A;  5CE6 A;  4S2R P;  4ZNG A;  1B6A A;  4KM3 A;  1YVM A;  4OOK A;  2GG5 A;  4MAT A;  4QR8 A;  3BIT A;  5FCF A;  1B59 A;  4R60 A;  5JHU A;  3BIP A;  2BWW A;  5FCH A;  5E5B A;  2Q96 A;  2BHB A;  2MAT A;  3L7G A;  3S6B A;  1WLR A;  4FO8 A;  1QXZ A;  2EA4 A;  2OKN A;  3BIQ A;  4RGZ 1;  4ZWP A;  1O0X A;  4A6W A;  2BH3 A;  2Q94 A;  4IKR A;  3PKD A;  2V3Y A;  4PNC A;  2EVO A;  3IG4 A;  2GG7 A;  2B3H A;  1BOA A;  2GGC A;  1YJ3 A;  4FUK A;  4IDY A;  2GG3 A;  2GZ5 A;  1PV9 A;  5CLS A;  5JFR A;  2B3K A;  4U73 A;  4U75 A;  4FLJ A;  1WL6 A;  1WY2 A;  2IW2 A;  4U71 A;  2NQ6 A;  4A6V A;  1C21 A;  1R5G A;  3RVA A;  4U6E A;  4Z7M A;  4FLK A;  4IF7 A;  3D27 A;  4RZZ A;  3TAV A;  2GU4 A;  1C24 A;  1QXW A;  1C27 A;  1KQ0 A;  2P9A A;  2V3Z A;  1YW8 A;  3IU9 A;  4HXX A;  4S00 A;  2GG9 A;  3PKB A;  2BHA A;  1BN5 A;  3CTZ A;  5CDE A;  3MR1 A;  5JI6 A;  2EVM A;  4IKT A;  1Y1N A; 
#chains in the Genus database with same CATH topology
 2BWX A;  2GGB A;  4FO7 A;  3CB6 A;  5CDV A;  4B28 A;  1WBQ A;  2GU5 A;  3CB5 A;  1N51 A;  4PV4 A;  1M35 A;  1YW7 A;  2BWU A;  2BWS A;  3MX6 A;  4U69 A;  4ZWU A;  4U1B A;  3ROR A;  1A16 A;  1WN1 A;  2GTX A;  4IKS A;  2BN7 A;  2BWY A;  4FLI A;  2V6C A;  2ADU A;  5CNX A;  5CDL A;  4U6J A;  2NQ7 A;  3IU8 A;  2BHC A;  3PKC A;  1QZY A;  4RZY A;  2GG0 A;  3Q6D A;  1R58 A;  2GG2 A;  4S01 A;  2B3L A;  1KQ9 A;  4IEC A;  2Q8K A;  1JAW A;  4IU6 A;  2OAZ A;  2V3X A;  3FMR A;  4U6W A;  2G6P A;  1WKM A;  2DFI A;  4U76 A;  3TB5 A;  4IPA A;  2HOW A;  1YW9 A;  1R5H A;  3IU7 A;  1KP0 A;  2GG8 A;  4U6Z A;  2ZSG A;  1WL9 A;  4IKU A;  1C22 A;  1MAT A;  5CIK A;  3PKA A;  2P99 A;  4S2T P;  1W7V A;  2Q95 A;  1CHM A;  1XGO A;  3PKE A;  4FKC A;  2GU7 A;  3FMQ A;  4EGE A;  4JUQ A;  4ZWO A;  3MAT A;  4U6C A;  4FLL A;  2GA2 A;  2BHD A;  2GU6 A;  2BWT A;  2BB7 A;  3FM3 A;  5D6E A;  2Q92 A;  1XNZ A;  1XGS A;  1QXY A;  1W2M A;  1XGN A;  3L24 A;  2BWV A;  2P98 A;  1XGM A;  2EVC A;  5D6F A;  1C23 A;  2EA2 A;  2Q93 A;  4U70 A;  5CE6 A;  4S2R P;  4ZNG A;  1B6A A;  4KM3 A;  1YVM A;  4OOK A;  2GG5 A;  4MAT A;  4QR8 A;  3BIT A;  5FCF A;  1B59 A;  4R60 A;  5JHU A;  3BIP A;  2BWW A;  5FCH A;  5E5B A;  2Q96 A;  2BHB A;  2MAT A;  3L7G A;  3S6B A;  1WLR A;  4FO8 A;  1QXZ A;  2EA4 A;  2OKN A;  3BIQ A;  4RGZ 1;  4ZWP A;  1O0X A;  4A6W A;  2BH3 A;  2Q94 A;  4IKR A;  3PKD A;  2V3Y A;  4PNC A;  2EVO A;  3IG4 A;  2GG7 A;  2B3H A;  1BOA A;  2GGC A;  1YJ3 A;  4FUK A;  4IDY A;  2GG3 A;  2GZ5 A;  1PV9 A;  5CLS A;  5JFR A;  2B3K A;  4U73 A;  4U75 A;  4FLJ A;  1WL6 A;  1WY2 A;  2IW2 A;  4U71 A;  2NQ6 A;  4A6V A;  1C21 A;  1R5G A;  3RVA A;  4U6E A;  4Z7M A;  4FLK A;  4IF7 A;  3D27 A;  4RZZ A;  3TAV A;  2GU4 A;  1C24 A;  1QXW A;  1C27 A;  1KQ0 A;  2P9A A;  2V3Z A;  1YW8 A;  3IU9 A;  4HXX A;  4S00 A;  2GG9 A;  3PKB A;  2BHA A;  1BN5 A;  3CTZ A;  5CDE A;  3MR1 A;  5JI6 A;  2EVM A;  4IKT A;  1Y1N A; 
#chains in the Genus database with same CATH homology
 2BWX A;  2GGB A;  4FO7 A;  3CB6 A;  5CDV A;  4B28 A;  1WBQ A;  2GU5 A;  3CB5 A;  1N51 A;  4PV4 A;  1M35 A;  1YW7 A;  2BWU A;  2BWS A;  3MX6 A;  4U69 A;  4ZWU A;  4U1B A;  3ROR A;  1A16 A;  1WN1 A;  2GTX A;  4IKS A;  2BN7 A;  2BWY A;  4FLI A;  2V6C A;  2ADU A;  5CNX A;  5CDL A;  4U6J A;  2NQ7 A;  3IU8 A;  2BHC A;  3PKC A;  1QZY A;  4RZY A;  2GG0 A;  3Q6D A;  1R58 A;  2GG2 A;  4S01 A;  2B3L A;  1KQ9 A;  4IEC A;  2Q8K A;  1JAW A;  4IU6 A;  2OAZ A;  2V3X A;  3FMR A;  4U6W A;  2G6P A;  1WKM A;  2DFI A;  4U76 A;  3TB5 A;  4IPA A;  2HOW A;  1YW9 A;  1R5H A;  3IU7 A;  1KP0 A;  2GG8 A;  4U6Z A;  2ZSG A;  1WL9 A;  4IKU A;  1C22 A;  1MAT A;  5CIK A;  3PKA A;  2P99 A;  4S2T P;  1W7V A;  2Q95 A;  1CHM A;  1XGO A;  3PKE A;  4FKC A;  2GU7 A;  3FMQ A;  4EGE A;  4JUQ A;  4ZWO A;  3MAT A;  4U6C A;  4FLL A;  2GA2 A;  2BHD A;  2GU6 A;  2BWT A;  2BB7 A;  3FM3 A;  5D6E A;  2Q92 A;  1XNZ A;  1XGS A;  1QXY A;  1W2M A;  1XGN A;  3L24 A;  2BWV A;  2P98 A;  1XGM A;  2EVC A;  5D6F A;  1C23 A;  2EA2 A;  2Q93 A;  4U70 A;  5CE6 A;  4S2R P;  4ZNG A;  1B6A A;  4KM3 A;  1YVM A;  4OOK A;  2GG5 A;  4MAT A;  4QR8 A;  3BIT A;  5FCF A;  1B59 A;  4R60 A;  5JHU A;  3BIP A;  2BWW A;  5FCH A;  5E5B A;  2Q96 A;  2BHB A;  2MAT A;  3L7G A;  3S6B A;  1WLR A;  4FO8 A;  1QXZ A;  2EA4 A;  2OKN A;  3BIQ A;  4RGZ 1;  4ZWP A;  1O0X A;  4A6W A;  2BH3 A;  2Q94 A;  4IKR A;  3PKD A;  2V3Y A;  4PNC A;  2EVO A;  3IG4 A;  2GG7 A;  2B3H A;  1BOA A;  2GGC A;  1YJ3 A;  4FUK A;  4IDY A;  2GG3 A;  2GZ5 A;  1PV9 A;  5CLS A;  5JFR A;  2B3K A;  4U73 A;  4U75 A;  4FLJ A;  1WL6 A;  1WY2 A;  2IW2 A;  4U71 A;  2NQ6 A;  4A6V A;  1C21 A;  1R5G A;  3RVA A;  4U6E A;  4Z7M A;  4FLK A;  4IF7 A;  3D27 A;  4RZZ A;  3TAV A;  2GU4 A;  1C24 A;  1QXW A;  1C27 A;  1KQ0 A;  2P9A A;  2V3Z A;  1YW8 A;  3IU9 A;  4HXX A;  4S00 A;  2GG9 A;  3PKB A;  2BHA A;  1BN5 A;  3CTZ A;  5CDE A;  3MR1 A;  5JI6 A;  2EVM A;  4IKT A;  1Y1N A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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