3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
3CTZA 3MX6A 4S2RP 4JUQA 4EGEA 1WL9A 2GG9A 3Q6DA 3PKBA 2EVMA 1QXWA 3IU9A 3TAVA 2OAZA 1YVMA 1KP0A 4U6WA 4IKTA 4IDYA 4IKUA 2Q94A 1WKMA 2MATA 3PKDA 3BIQA 1WLRA 4IU6A 1N51A 1KQ9A 4ZWUA 2BWUA 1Y1NA 2ZSGA 2GGCA 2BHCA 4FLJA 2BWTA 3BITA 1WL6A 2B3KA 4U76A 2OKNA 2P98A 2Q96A 1YJ3A 1B6AA 4U6CA 1M35A 1CHMA 2GG2A 2GU4A 3BIPA 4S01A 2Q95A 2GU7A 2DFIA 2BN7A 3TB5A 1JAWA 2BWSA 2EA2A 1YW7A 2GU6A 4U6EA 4QR8A 1XGSA 2NQ6A 1W7VA 1MATA 2BHBA 2P99A 2B3LA 3PKEA 1R5HA 4FLLA 5CDVA 4RGZ1 4IPAA 1C22A 4ZWOA 2GA2A 1BN5A 2BHAA 4RZYA 3FMQA 5CIKA 4R60A 3IG4A 3S6BA 1C24A 4A6WA 1XGNA 2HOWA 1PV9A 5FCHA 4KM3A 3L7GA 5CNXA 2BHDA 3CB5A 3IU8A 5FCFA 4A6VA 4Z7MA 1W2MA 1C21A 4U70A 3IU7A 2V6CA 4U1BA 4ZNGA 3MR1A 4U75A 3PKAA 5JHUA 4FO8A 4B28A 1WBQA 2Q92A 4FO7A 4U6ZA 3D27A 1A16A 4U71A 1WY2A 2BH3A 5E5BA 5JFRA 4HXXA 2BB7A 2EVCA 2GZ5A 4S2TP 2GG5A 1YW9A 1XGOA 2BWYA 1QXYA 1YW8A 2BWVA 2IW2A 4FKCA 4FLIA 2EVOA 4U69A 2EA4A 5D6FA 3PKCA 4PNCA 1R5GA 4IKRA 5JI6A 4OOKA 5CDEA 2B3HA 2Q8KA 2GG3A 2Q93A 4S00A 4U73A 2GTXA 5CE6A 1BOAA 2GGBA 2P9AA 2V3ZA 2GU5A 1B59A 1C23A 4RZZA 5CDLA 4FUKA 2BWXA 4IKSA 2GG7A 1WN1A 3FMRA 1KQ0A 3FM3A 4FLKA 4U6JA 2V3YA 2GG8A 3MATA 2G6PA 1QXZA 4PV4A 3CB6A 1XGMA 2GG0A 2BWWA 5D6EA 4ZWPA 2V3XA 2ADUA 5CLSA 4IECA 4IF7A 3RVAA 3RORA 1C27A 1XNZA 1QZYA 4MATA 1R58A 2NQ7A 1O0XA 3L24A
chains in the Genus database with same CATH superfamily
3CTZA 3MX6A 4S2RP 4JUQA 4EGEA 1WL9A 2GG9A 3Q6DA 3PKBA 2EVMA 1QXWA 3IU9A 3TAVA 2OAZA 1YVMA 1KP0A 4U6WA 4IKTA 4IDYA 4IKUA 2Q94A 1WKMA 2MATA 3PKDA 3BIQA 1WLRA 4IU6A 1N51A 1KQ9A 4ZWUA 2BWUA 1Y1NA 2ZSGA 2GGCA 2BHCA 4FLJA 2BWTA 3BITA 1WL6A 2B3KA 4U76A 2OKNA 2P98A 2Q96A 1YJ3A 1B6AA 4U6CA 1M35A 1CHMA 2GG2A 2GU4A 3BIPA 4S01A 2Q95A 2GU7A 2DFIA 2BN7A 3TB5A 1JAWA 2BWSA 2EA2A 1YW7A 2GU6A 4U6EA 4QR8A 1XGSA 2NQ6A 1W7VA 1MATA 2BHBA 2P99A 2B3LA 3PKEA 1R5HA 4FLLA 5CDVA 4RGZ1 4IPAA 1C22A 4ZWOA 2GA2A 1BN5A 2BHAA 4RZYA 3FMQA 5CIKA 4R60A 3IG4A 3S6BA 1C24A 4A6WA 1XGNA 2HOWA 1PV9A 5FCHA 4KM3A 3L7GA 5CNXA 2BHDA 3CB5A 3IU8A 5FCFA 4A6VA 4Z7MA 1W2MA 1C21A 4U70A 3IU7A 2V6CA 4U1BA 4ZNGA 3MR1A 4U75A 3PKAA 5JHUA 4FO8A 4B28A 1WBQA 2Q92A 4FO7A 4U6ZA 3D27A 1A16A 4U71A 1WY2A 2BH3A 5E5BA 5JFRA 4HXXA 2BB7A 2EVCA 2GZ5A 4S2TP 2GG5A 1YW9A 1XGOA 2BWYA 1QXYA 1YW8A 2BWVA 2IW2A 4FKCA 4FLIA 2EVOA 4U69A 2EA4A 5D6FA 3PKCA 4PNCA 1R5GA 4IKRA 5JI6A 4OOKA 5CDEA 2B3HA 2Q8KA 2GG3A 2Q93A 4S00A 4U73A 2GTXA 5CE6A 1BOAA 2GGBA 2P9AA 2V3ZA 2GU5A 1B59A 1C23A 4RZZA 5CDLA 4FUKA 2BWXA 4IKSA 2GG7A 1WN1A 3FMRA 1KQ0A 3FM3A 4FLKA 4U6JA 2V3YA 2GG8A 3MATA 2G6PA 1QXZA 4PV4A 3CB6A 1XGMA 2GG0A 2BWWA 5D6EA 4ZWPA 2V3XA 2ADUA 5CLSA 4IECA 4IF7A 3RVAA 3RORA 1C27A 1XNZA 1QZYA 4MATA 1R58A 2NQ7A 1O0XA 3L24A
chains in the Genus database with same CATH topology
3CTZA 3MX6A 4S2RP 4JUQA 4EGEA 1WL9A 2GG9A 3Q6DA 3PKBA 2EVMA 1QXWA 3IU9A 3TAVA 2OAZA 1YVMA 1KP0A 4U6WA 4IKTA 4IDYA 4IKUA 2Q94A 1WKMA 2MATA 3PKDA 3BIQA 1WLRA 4IU6A 1N51A 1KQ9A 4ZWUA 2BWUA 1Y1NA 2ZSGA 2GGCA 2BHCA 4FLJA 2BWTA 3BITA 1WL6A 2B3KA 4U76A 2OKNA 2P98A 2Q96A 1YJ3A 1B6AA 4U6CA 1M35A 1CHMA 2GG2A 2GU4A 3BIPA 4S01A 2Q95A 2GU7A 2DFIA 2BN7A 3TB5A 1JAWA 2BWSA 2EA2A 1YW7A 2GU6A 4U6EA 4QR8A 1XGSA 2NQ6A 1W7VA 1MATA 2BHBA 2P99A 2B3LA 3PKEA 1R5HA 4FLLA 5CDVA 4RGZ1 4IPAA 1C22A 4ZWOA 2GA2A 1BN5A 2BHAA 4RZYA 3FMQA 5CIKA 4R60A 3IG4A 3S6BA 1C24A 4A6WA 1XGNA 2HOWA 1PV9A 5FCHA 4KM3A 3L7GA 5CNXA 2BHDA 3CB5A 3IU8A 5FCFA 4A6VA 4Z7MA 1W2MA 1C21A 4U70A 3IU7A 2V6CA 4U1BA 4ZNGA 3MR1A 4U75A 3PKAA 5JHUA 4FO8A 4B28A 1WBQA 2Q92A 4FO7A 4U6ZA 3D27A 1A16A 4U71A 1WY2A 2BH3A 5E5BA 5JFRA 4HXXA 2BB7A 2EVCA 2GZ5A 4S2TP 2GG5A 1YW9A 1XGOA 2BWYA 1QXYA 1YW8A 2BWVA 2IW2A 4FKCA 4FLIA 2EVOA 4U69A 2EA4A 5D6FA 3PKCA 4PNCA 1R5GA 4IKRA 5JI6A 4OOKA 5CDEA 2B3HA 2Q8KA 2GG3A 2Q93A 4S00A 4U73A 2GTXA 5CE6A 1BOAA 2GGBA 2P9AA 2V3ZA 2GU5A 1B59A 1C23A 4RZZA 5CDLA 4FUKA 2BWXA 4IKSA 2GG7A 1WN1A 3FMRA 1KQ0A 3FM3A 4FLKA 4U6JA 2V3YA 2GG8A 3MATA 2G6PA 1QXZA 4PV4A 3CB6A 1XGMA 2GG0A 2BWWA 5D6EA 4ZWPA 2V3XA 2ADUA 5CLSA 4IECA 4IF7A 3RVAA 3RORA 1C27A 1XNZA 1QZYA 4MATA 1R58A 2NQ7A 1O0XA 3L24A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3CTZ A;  3MX6 A;  4S2R P;  4JUQ A;  4EGE A;  1WL9 A;  2GG9 A;  3Q6D A;  3PKB A;  2EVM A;  1QXW A;  3IU9 A;  3TAV A;  2OAZ A;  1YVM A;  1KP0 A;  4U6W A;  4IKT A;  4IDY A;  4IKU A;  2Q94 A;  1WKM A;  2MAT A;  3PKD A;  3BIQ A;  1WLR A;  4IU6 A;  1N51 A;  1KQ9 A;  4ZWU A;  2BWU A;  1Y1N A;  2ZSG A;  2GGC A;  2BHC A;  4FLJ A;  2BWT A;  3BIT A;  1WL6 A;  2B3K A;  4U76 A;  2OKN A;  2P98 A;  2Q96 A;  1YJ3 A;  1B6A A;  4U6C A;  1M35 A;  1CHM A;  2GG2 A;  2GU4 A;  3BIP A;  4S01 A;  2Q95 A;  2GU7 A;  2DFI A;  2BN7 A;  3TB5 A;  1JAW A;  2BWS A;  2EA2 A;  1YW7 A;  2GU6 A;  4U6E A;  4QR8 A;  1XGS A;  2NQ6 A;  1W7V A;  1MAT A;  2BHB A;  2P99 A;  2B3L A;  3PKE A;  1R5H A;  4FLL A;  5CDV A;  4RGZ 1;  4IPA A;  1C22 A;  4ZWO A;  2GA2 A;  1BN5 A;  2BHA A;  4RZY A;  3FMQ A;  5CIK A;  4R60 A;  3IG4 A;  3S6B A;  1C24 A;  4A6W A;  1XGN A;  2HOW A;  1PV9 A;  5FCH A;  4KM3 A;  3L7G A;  5CNX A;  2BHD A;  3CB5 A;  3IU8 A;  5FCF A;  4A6V A;  4Z7M A;  1W2M A;  1C21 A;  4U70 A;  3IU7 A;  2V6C A;  4U1B A;  4ZNG A;  3MR1 A;  4U75 A;  3PKA A;  5JHU A;  4FO8 A;  4B28 A;  1WBQ A;  2Q92 A;  4FO7 A;  4U6Z A;  3D27 A;  1A16 A;  4U71 A;  1WY2 A;  2BH3 A;  5E5B A;  5JFR A;  4HXX A;  2BB7 A;  2EVC A;  2GZ5 A;  4S2T P;  2GG5 A;  1YW9 A;  1XGO A;  2BWY A;  1QXY A;  1YW8 A;  2BWV A;  2IW2 A;  4FKC A;  4FLI A;  2EVO A;  4U69 A;  2EA4 A;  5D6F A;  3PKC A;  4PNC A;  1R5G A;  4IKR A;  5JI6 A;  4OOK A;  5CDE A;  2B3H A;  2Q8K A;  2GG3 A;  2Q93 A;  4S00 A;  4U73 A;  2GTX A;  5CE6 A;  1BOA A;  2GGB A;  2P9A A;  2V3Z A;  2GU5 A;  1B59 A;  1C23 A;  4RZZ A;  5CDL A;  4FUK A;  2BWX A;  4IKS A;  2GG7 A;  1WN1 A;  3FMR A;  1KQ0 A;  3FM3 A;  4FLK A;  4U6J A;  2V3Y A;  2GG8 A;  3MAT A;  2G6P A;  1QXZ A;  4PV4 A;  3CB6 A;  1XGM A;  2GG0 A;  2BWW A;  5D6E A;  4ZWP A;  2V3X A;  2ADU A;  5CLS A;  4IEC A;  4IF7 A;  3RVA A;  3ROR A;  1C27 A;  1XNZ A;  1QZY A;  4MAT A;  1R58 A;  2NQ7 A;  1O0X A;  3L24 A; 
#chains in the Genus database with same CATH topology
 3CTZ A;  3MX6 A;  4S2R P;  4JUQ A;  4EGE A;  1WL9 A;  2GG9 A;  3Q6D A;  3PKB A;  2EVM A;  1QXW A;  3IU9 A;  3TAV A;  2OAZ A;  1YVM A;  1KP0 A;  4U6W A;  4IKT A;  4IDY A;  4IKU A;  2Q94 A;  1WKM A;  2MAT A;  3PKD A;  3BIQ A;  1WLR A;  4IU6 A;  1N51 A;  1KQ9 A;  4ZWU A;  2BWU A;  1Y1N A;  2ZSG A;  2GGC A;  2BHC A;  4FLJ A;  2BWT A;  3BIT A;  1WL6 A;  2B3K A;  4U76 A;  2OKN A;  2P98 A;  2Q96 A;  1YJ3 A;  1B6A A;  4U6C A;  1M35 A;  1CHM A;  2GG2 A;  2GU4 A;  3BIP A;  4S01 A;  2Q95 A;  2GU7 A;  2DFI A;  2BN7 A;  3TB5 A;  1JAW A;  2BWS A;  2EA2 A;  1YW7 A;  2GU6 A;  4U6E A;  4QR8 A;  1XGS A;  2NQ6 A;  1W7V A;  1MAT A;  2BHB A;  2P99 A;  2B3L A;  3PKE A;  1R5H A;  4FLL A;  5CDV A;  4RGZ 1;  4IPA A;  1C22 A;  4ZWO A;  2GA2 A;  1BN5 A;  2BHA A;  4RZY A;  3FMQ A;  5CIK A;  4R60 A;  3IG4 A;  3S6B A;  1C24 A;  4A6W A;  1XGN A;  2HOW A;  1PV9 A;  5FCH A;  4KM3 A;  3L7G A;  5CNX A;  2BHD A;  3CB5 A;  3IU8 A;  5FCF A;  4A6V A;  4Z7M A;  1W2M A;  1C21 A;  4U70 A;  3IU7 A;  2V6C A;  4U1B A;  4ZNG A;  3MR1 A;  4U75 A;  3PKA A;  5JHU A;  4FO8 A;  4B28 A;  1WBQ A;  2Q92 A;  4FO7 A;  4U6Z A;  3D27 A;  1A16 A;  4U71 A;  1WY2 A;  2BH3 A;  5E5B A;  5JFR A;  4HXX A;  2BB7 A;  2EVC A;  2GZ5 A;  4S2T P;  2GG5 A;  1YW9 A;  1XGO A;  2BWY A;  1QXY A;  1YW8 A;  2BWV A;  2IW2 A;  4FKC A;  4FLI A;  2EVO A;  4U69 A;  2EA4 A;  5D6F A;  3PKC A;  4PNC A;  1R5G A;  4IKR A;  5JI6 A;  4OOK A;  5CDE A;  2B3H A;  2Q8K A;  2GG3 A;  2Q93 A;  4S00 A;  4U73 A;  2GTX A;  5CE6 A;  1BOA A;  2GGB A;  2P9A A;  2V3Z A;  2GU5 A;  1B59 A;  1C23 A;  4RZZ A;  5CDL A;  4FUK A;  2BWX A;  4IKS A;  2GG7 A;  1WN1 A;  3FMR A;  1KQ0 A;  3FM3 A;  4FLK A;  4U6J A;  2V3Y A;  2GG8 A;  3MAT A;  2G6P A;  1QXZ A;  4PV4 A;  3CB6 A;  1XGM A;  2GG0 A;  2BWW A;  5D6E A;  4ZWP A;  2V3X A;  2ADU A;  5CLS A;  4IEC A;  4IF7 A;  3RVA A;  3ROR A;  1C27 A;  1XNZ A;  1QZY A;  4MAT A;  1R58 A;  2NQ7 A;  1O0X A;  3L24 A; 
#chains in the Genus database with same CATH homology
 3CTZ A;  3MX6 A;  4S2R P;  4JUQ A;  4EGE A;  1WL9 A;  2GG9 A;  3Q6D A;  3PKB A;  2EVM A;  1QXW A;  3IU9 A;  3TAV A;  2OAZ A;  1YVM A;  1KP0 A;  4U6W A;  4IKT A;  4IDY A;  4IKU A;  2Q94 A;  1WKM A;  2MAT A;  3PKD A;  3BIQ A;  1WLR A;  4IU6 A;  1N51 A;  1KQ9 A;  4ZWU A;  2BWU A;  1Y1N A;  2ZSG A;  2GGC A;  2BHC A;  4FLJ A;  2BWT A;  3BIT A;  1WL6 A;  2B3K A;  4U76 A;  2OKN A;  2P98 A;  2Q96 A;  1YJ3 A;  1B6A A;  4U6C A;  1M35 A;  1CHM A;  2GG2 A;  2GU4 A;  3BIP A;  4S01 A;  2Q95 A;  2GU7 A;  2DFI A;  2BN7 A;  3TB5 A;  1JAW A;  2BWS A;  2EA2 A;  1YW7 A;  2GU6 A;  4U6E A;  4QR8 A;  1XGS A;  2NQ6 A;  1W7V A;  1MAT A;  2BHB A;  2P99 A;  2B3L A;  3PKE A;  1R5H A;  4FLL A;  5CDV A;  4RGZ 1;  4IPA A;  1C22 A;  4ZWO A;  2GA2 A;  1BN5 A;  2BHA A;  4RZY A;  3FMQ A;  5CIK A;  4R60 A;  3IG4 A;  3S6B A;  1C24 A;  4A6W A;  1XGN A;  2HOW A;  1PV9 A;  5FCH A;  4KM3 A;  3L7G A;  5CNX A;  2BHD A;  3CB5 A;  3IU8 A;  5FCF A;  4A6V A;  4Z7M A;  1W2M A;  1C21 A;  4U70 A;  3IU7 A;  2V6C A;  4U1B A;  4ZNG A;  3MR1 A;  4U75 A;  3PKA A;  5JHU A;  4FO8 A;  4B28 A;  1WBQ A;  2Q92 A;  4FO7 A;  4U6Z A;  3D27 A;  1A16 A;  4U71 A;  1WY2 A;  2BH3 A;  5E5B A;  5JFR A;  4HXX A;  2BB7 A;  2EVC A;  2GZ5 A;  4S2T P;  2GG5 A;  1YW9 A;  1XGO A;  2BWY A;  1QXY A;  1YW8 A;  2BWV A;  2IW2 A;  4FKC A;  4FLI A;  2EVO A;  4U69 A;  2EA4 A;  5D6F A;  3PKC A;  4PNC A;  1R5G A;  4IKR A;  5JI6 A;  4OOK A;  5CDE A;  2B3H A;  2Q8K A;  2GG3 A;  2Q93 A;  4S00 A;  4U73 A;  2GTX A;  5CE6 A;  1BOA A;  2GGB A;  2P9A A;  2V3Z A;  2GU5 A;  1B59 A;  1C23 A;  4RZZ A;  5CDL A;  4FUK A;  2BWX A;  4IKS A;  2GG7 A;  1WN1 A;  3FMR A;  1KQ0 A;  3FM3 A;  4FLK A;  4U6J A;  2V3Y A;  2GG8 A;  3MAT A;  2G6P A;  1QXZ A;  4PV4 A;  3CB6 A;  1XGM A;  2GG0 A;  2BWW A;  5D6E A;  4ZWP A;  2V3X A;  2ADU A;  5CLS A;  4IEC A;  4IF7 A;  3RVA A;  3ROR A;  1C27 A;  1XNZ A;  1QZY A;  4MAT A;  1R58 A;  2NQ7 A;  1O0X A;  3L24 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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