3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
1WL6A 2GG7A 2ADUA 4U1BA 4HXXA 3TAVA 2B3HA 4FLKA 3L24A 3FMQA 4U70A 2B3LA 2BWXA 1C27A 3RORA 1R5GA 1C24A 2BB7A 2DFIA 2P99A 2GU5A 5JI6A 3Q6DA 1KP0A 2OAZA 5D6FA 4FKCA 5CIKA 4PNCA 1QZYA 4U69A 4FLJA 5CLSA 3MATA 1YVMA 5JHUA 4U6ZA 4A6VA 2BHBA 2MATA 2BH3A 1R58A 2BWTA 4FLIA 3S6BA 5CDEA 2Q94A 3BIPA 1WLRA 1XGOA 3MR1A 3MX6A 4ZWUA 4U76A 2BWUA 4IKUA 1YJ3A 1YW8A 1C21A 5CNXA 1YW9A 1KQ0A 3PKEA 1BOAA 4IKSA 1WL9A 2V3ZA 2ZSGA 3IU9A 2NQ6A 4R60A 1QXZA 2EA2A 4IU6A 1XGNA 4S2TP 2GG2A 2V6CA 2G6PA 4FLLA 1WN1A 2BWYA 3IU7A 2GG3A 2B3KA 2BHDA 4IDYA 4FO8A 4MATA 2Q96A 4RZZA 2P9AA 2GG0A 3D27A 4U6CA 2BWWA 4A6WA 2V3XA 4IKTA 2GZ5A 3FM3A 1PV9A 1WBQA 4S00A 2GGCA 3FMRA 3PKCA 4ZNGA 4EGEA 4FO7A 1W7VA 3BIQA 4JUQA 1WKMA 1B6AA 4KM3A 2EVMA 4IECA 1XGSA 3PKDA 1A16A 4RGZ1 4Z7MA 2P98A 2NQ7A 3PKBA 2GU6A 1CHMA 2GG8A 2EVCA 1N51A 4PV4A 3L7GA 2BWVA 1XGMA 2GA2A 3TB5A 1M35A 1WY2A 3CB5A 4S01A 3IG4A 5CDLA 5FCHA 2Q95A 2BHAA 3PKAA 3CTZA 2IW2A 3RVAA 1QXWA 2GU4A 3CB6A 2EVOA 2GG5A 5JFRA 1C23A 4U75A 2BWSA 1BN5A 2EA4A 2BN7A 1Y1NA 3IU8A 2Q92A 4U6WA 4IF7A 2V3YA 1JAWA 2HOWA 4U6EA 1YW7A 4FUKA 1O0XA 5CDVA 2Q8KA 4U71A 2OKNA 2GU7A 4U6JA 1R5HA 1QXYA 4ZWPA 2GGBA 5E5BA 5FCFA 1KQ9A 2Q93A 2GG9A 4S2RP 4U73A 4B28A 2GTXA 2BHCA 1C22A 4QR8A 4IKRA 4ZWOA 5D6EA 4IPAA 3BITA 1W2MA 4OOKA 5CE6A 4RZYA 1B59A 1MATA 1XNZA
chains in the Genus database with same CATH superfamily
1WL6A 2GG7A 2ADUA 4U1BA 4HXXA 3TAVA 2B3HA 4FLKA 3L24A 3FMQA 4U70A 2B3LA 2BWXA 1C27A 3RORA 1R5GA 1C24A 2BB7A 2DFIA 2P99A 2GU5A 5JI6A 3Q6DA 1KP0A 2OAZA 5D6FA 4FKCA 5CIKA 4PNCA 1QZYA 4U69A 4FLJA 5CLSA 3MATA 1YVMA 5JHUA 4U6ZA 4A6VA 2BHBA 2MATA 2BH3A 1R58A 2BWTA 4FLIA 3S6BA 5CDEA 2Q94A 3BIPA 1WLRA 1XGOA 3MR1A 3MX6A 4ZWUA 4U76A 2BWUA 4IKUA 1YJ3A 1YW8A 1C21A 5CNXA 1YW9A 1KQ0A 3PKEA 1BOAA 4IKSA 1WL9A 2V3ZA 2ZSGA 3IU9A 2NQ6A 4R60A 1QXZA 2EA2A 4IU6A 1XGNA 4S2TP 2GG2A 2V6CA 2G6PA 4FLLA 1WN1A 2BWYA 3IU7A 2GG3A 2B3KA 2BHDA 4IDYA 4FO8A 4MATA 2Q96A 4RZZA 2P9AA 2GG0A 3D27A 4U6CA 2BWWA 4A6WA 2V3XA 4IKTA 2GZ5A 3FM3A 1PV9A 1WBQA 4S00A 2GGCA 3FMRA 3PKCA 4ZNGA 4EGEA 4FO7A 1W7VA 3BIQA 4JUQA 1WKMA 1B6AA 4KM3A 2EVMA 4IECA 1XGSA 3PKDA 1A16A 4RGZ1 4Z7MA 2P98A 2NQ7A 3PKBA 2GU6A 1CHMA 2GG8A 2EVCA 1N51A 4PV4A 3L7GA 2BWVA 1XGMA 2GA2A 3TB5A 1M35A 1WY2A 3CB5A 4S01A 3IG4A 5CDLA 5FCHA 2Q95A 2BHAA 3PKAA 3CTZA 2IW2A 3RVAA 1QXWA 2GU4A 3CB6A 2EVOA 2GG5A 5JFRA 1C23A 4U75A 2BWSA 1BN5A 2EA4A 2BN7A 1Y1NA 3IU8A 2Q92A 4U6WA 4IF7A 2V3YA 1JAWA 2HOWA 4U6EA 1YW7A 4FUKA 1O0XA 5CDVA 2Q8KA 4U71A 2OKNA 2GU7A 4U6JA 1R5HA 1QXYA 4ZWPA 2GGBA 5E5BA 5FCFA 1KQ9A 2Q93A 2GG9A 4S2RP 4U73A 4B28A 2GTXA 2BHCA 1C22A 4QR8A 4IKRA 4ZWOA 5D6EA 4IPAA 3BITA 1W2MA 4OOKA 5CE6A 4RZYA 1B59A 1MATA 1XNZA
chains in the Genus database with same CATH topology
1WL6A 2GG7A 2ADUA 4U1BA 4HXXA 3TAVA 2B3HA 4FLKA 3L24A 3FMQA 4U70A 2B3LA 2BWXA 1C27A 3RORA 1R5GA 1C24A 2BB7A 2DFIA 2P99A 2GU5A 5JI6A 3Q6DA 1KP0A 2OAZA 5D6FA 4FKCA 5CIKA 4PNCA 1QZYA 4U69A 4FLJA 5CLSA 3MATA 1YVMA 5JHUA 4U6ZA 4A6VA 2BHBA 2MATA 2BH3A 1R58A 2BWTA 4FLIA 3S6BA 5CDEA 2Q94A 3BIPA 1WLRA 1XGOA 3MR1A 3MX6A 4ZWUA 4U76A 2BWUA 4IKUA 1YJ3A 1YW8A 1C21A 5CNXA 1YW9A 1KQ0A 3PKEA 1BOAA 4IKSA 1WL9A 2V3ZA 2ZSGA 3IU9A 2NQ6A 4R60A 1QXZA 2EA2A 4IU6A 1XGNA 4S2TP 2GG2A 2V6CA 2G6PA 4FLLA 1WN1A 2BWYA 3IU7A 2GG3A 2B3KA 2BHDA 4IDYA 4FO8A 4MATA 2Q96A 4RZZA 2P9AA 2GG0A 3D27A 4U6CA 2BWWA 4A6WA 2V3XA 4IKTA 2GZ5A 3FM3A 1PV9A 1WBQA 4S00A 2GGCA 3FMRA 3PKCA 4ZNGA 4EGEA 4FO7A 1W7VA 3BIQA 4JUQA 1WKMA 1B6AA 4KM3A 2EVMA 4IECA 1XGSA 3PKDA 1A16A 4RGZ1 4Z7MA 2P98A 2NQ7A 3PKBA 2GU6A 1CHMA 2GG8A 2EVCA 1N51A 4PV4A 3L7GA 2BWVA 1XGMA 2GA2A 3TB5A 1M35A 1WY2A 3CB5A 4S01A 3IG4A 5CDLA 5FCHA 2Q95A 2BHAA 3PKAA 3CTZA 2IW2A 3RVAA 1QXWA 2GU4A 3CB6A 2EVOA 2GG5A 5JFRA 1C23A 4U75A 2BWSA 1BN5A 2EA4A 2BN7A 1Y1NA 3IU8A 2Q92A 4U6WA 4IF7A 2V3YA 1JAWA 2HOWA 4U6EA 1YW7A 4FUKA 1O0XA 5CDVA 2Q8KA 4U71A 2OKNA 2GU7A 4U6JA 1R5HA 1QXYA 4ZWPA 2GGBA 5E5BA 5FCFA 1KQ9A 2Q93A 2GG9A 4S2RP 4U73A 4B28A 2GTXA 2BHCA 1C22A 4QR8A 4IKRA 4ZWOA 5D6EA 4IPAA 3BITA 1W2MA 4OOKA 5CE6A 4RZYA 1B59A 1MATA 1XNZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WL6 A;  2GG7 A;  2ADU A;  4U1B A;  4HXX A;  3TAV A;  2B3H A;  4FLK A;  3L24 A;  3FMQ A;  4U70 A;  2B3L A;  2BWX A;  1C27 A;  3ROR A;  1R5G A;  1C24 A;  2BB7 A;  2DFI A;  2P99 A;  2GU5 A;  5JI6 A;  3Q6D A;  1KP0 A;  2OAZ A;  5D6F A;  4FKC A;  5CIK A;  4PNC A;  1QZY A;  4U69 A;  4FLJ A;  5CLS A;  3MAT A;  1YVM A;  5JHU A;  4U6Z A;  4A6V A;  2BHB A;  2MAT A;  2BH3 A;  1R58 A;  2BWT A;  4FLI A;  3S6B A;  5CDE A;  2Q94 A;  3BIP A;  1WLR A;  1XGO A;  3MR1 A;  3MX6 A;  4ZWU A;  4U76 A;  2BWU A;  4IKU A;  1YJ3 A;  1YW8 A;  1C21 A;  5CNX A;  1YW9 A;  1KQ0 A;  3PKE A;  1BOA A;  4IKS A;  1WL9 A;  2V3Z A;  2ZSG A;  3IU9 A;  2NQ6 A;  4R60 A;  1QXZ A;  2EA2 A;  4IU6 A;  1XGN A;  4S2T P;  2GG2 A;  2V6C A;  2G6P A;  4FLL A;  1WN1 A;  2BWY A;  3IU7 A;  2GG3 A;  2B3K A;  2BHD A;  4IDY A;  4FO8 A;  4MAT A;  2Q96 A;  4RZZ A;  2P9A A;  2GG0 A;  3D27 A;  4U6C A;  2BWW A;  4A6W A;  2V3X A;  4IKT A;  2GZ5 A;  3FM3 A;  1PV9 A;  1WBQ A;  4S00 A;  2GGC A;  3FMR A;  3PKC A;  4ZNG A;  4EGE A;  4FO7 A;  1W7V A;  3BIQ A;  4JUQ A;  1WKM A;  1B6A A;  4KM3 A;  2EVM A;  4IEC A;  1XGS A;  3PKD A;  1A16 A;  4RGZ 1;  4Z7M A;  2P98 A;  2NQ7 A;  3PKB A;  2GU6 A;  1CHM A;  2GG8 A;  2EVC A;  1N51 A;  4PV4 A;  3L7G A;  2BWV A;  1XGM A;  2GA2 A;  3TB5 A;  1M35 A;  1WY2 A;  3CB5 A;  4S01 A;  3IG4 A;  5CDL A;  5FCH A;  2Q95 A;  2BHA A;  3PKA A;  3CTZ A;  2IW2 A;  3RVA A;  1QXW A;  2GU4 A;  3CB6 A;  2EVO A;  2GG5 A;  5JFR A;  1C23 A;  4U75 A;  2BWS A;  1BN5 A;  2EA4 A;  2BN7 A;  1Y1N A;  3IU8 A;  2Q92 A;  4U6W A;  4IF7 A;  2V3Y A;  1JAW A;  2HOW A;  4U6E A;  1YW7 A;  4FUK A;  1O0X A;  5CDV A;  2Q8K A;  4U71 A;  2OKN A;  2GU7 A;  4U6J A;  1R5H A;  1QXY A;  4ZWP A;  2GGB A;  5E5B A;  5FCF A;  1KQ9 A;  2Q93 A;  2GG9 A;  4S2R P;  4U73 A;  4B28 A;  2GTX A;  2BHC A;  1C22 A;  4QR8 A;  4IKR A;  4ZWO A;  5D6E A;  4IPA A;  3BIT A;  1W2M A;  4OOK A;  5CE6 A;  4RZY A;  1B59 A;  1MAT A;  1XNZ A; 
#chains in the Genus database with same CATH topology
 1WL6 A;  2GG7 A;  2ADU A;  4U1B A;  4HXX A;  3TAV A;  2B3H A;  4FLK A;  3L24 A;  3FMQ A;  4U70 A;  2B3L A;  2BWX A;  1C27 A;  3ROR A;  1R5G A;  1C24 A;  2BB7 A;  2DFI A;  2P99 A;  2GU5 A;  5JI6 A;  3Q6D A;  1KP0 A;  2OAZ A;  5D6F A;  4FKC A;  5CIK A;  4PNC A;  1QZY A;  4U69 A;  4FLJ A;  5CLS A;  3MAT A;  1YVM A;  5JHU A;  4U6Z A;  4A6V A;  2BHB A;  2MAT A;  2BH3 A;  1R58 A;  2BWT A;  4FLI A;  3S6B A;  5CDE A;  2Q94 A;  3BIP A;  1WLR A;  1XGO A;  3MR1 A;  3MX6 A;  4ZWU A;  4U76 A;  2BWU A;  4IKU A;  1YJ3 A;  1YW8 A;  1C21 A;  5CNX A;  1YW9 A;  1KQ0 A;  3PKE A;  1BOA A;  4IKS A;  1WL9 A;  2V3Z A;  2ZSG A;  3IU9 A;  2NQ6 A;  4R60 A;  1QXZ A;  2EA2 A;  4IU6 A;  1XGN A;  4S2T P;  2GG2 A;  2V6C A;  2G6P A;  4FLL A;  1WN1 A;  2BWY A;  3IU7 A;  2GG3 A;  2B3K A;  2BHD A;  4IDY A;  4FO8 A;  4MAT A;  2Q96 A;  4RZZ A;  2P9A A;  2GG0 A;  3D27 A;  4U6C A;  2BWW A;  4A6W A;  2V3X A;  4IKT A;  2GZ5 A;  3FM3 A;  1PV9 A;  1WBQ A;  4S00 A;  2GGC A;  3FMR A;  3PKC A;  4ZNG A;  4EGE A;  4FO7 A;  1W7V A;  3BIQ A;  4JUQ A;  1WKM A;  1B6A A;  4KM3 A;  2EVM A;  4IEC A;  1XGS A;  3PKD A;  1A16 A;  4RGZ 1;  4Z7M A;  2P98 A;  2NQ7 A;  3PKB A;  2GU6 A;  1CHM A;  2GG8 A;  2EVC A;  1N51 A;  4PV4 A;  3L7G A;  2BWV A;  1XGM A;  2GA2 A;  3TB5 A;  1M35 A;  1WY2 A;  3CB5 A;  4S01 A;  3IG4 A;  5CDL A;  5FCH A;  2Q95 A;  2BHA A;  3PKA A;  3CTZ A;  2IW2 A;  3RVA A;  1QXW A;  2GU4 A;  3CB6 A;  2EVO A;  2GG5 A;  5JFR A;  1C23 A;  4U75 A;  2BWS A;  1BN5 A;  2EA4 A;  2BN7 A;  1Y1N A;  3IU8 A;  2Q92 A;  4U6W A;  4IF7 A;  2V3Y A;  1JAW A;  2HOW A;  4U6E A;  1YW7 A;  4FUK A;  1O0X A;  5CDV A;  2Q8K A;  4U71 A;  2OKN A;  2GU7 A;  4U6J A;  1R5H A;  1QXY A;  4ZWP A;  2GGB A;  5E5B A;  5FCF A;  1KQ9 A;  2Q93 A;  2GG9 A;  4S2R P;  4U73 A;  4B28 A;  2GTX A;  2BHC A;  1C22 A;  4QR8 A;  4IKR A;  4ZWO A;  5D6E A;  4IPA A;  3BIT A;  1W2M A;  4OOK A;  5CE6 A;  4RZY A;  1B59 A;  1MAT A;  1XNZ A; 
#chains in the Genus database with same CATH homology
 1WL6 A;  2GG7 A;  2ADU A;  4U1B A;  4HXX A;  3TAV A;  2B3H A;  4FLK A;  3L24 A;  3FMQ A;  4U70 A;  2B3L A;  2BWX A;  1C27 A;  3ROR A;  1R5G A;  1C24 A;  2BB7 A;  2DFI A;  2P99 A;  2GU5 A;  5JI6 A;  3Q6D A;  1KP0 A;  2OAZ A;  5D6F A;  4FKC A;  5CIK A;  4PNC A;  1QZY A;  4U69 A;  4FLJ A;  5CLS A;  3MAT A;  1YVM A;  5JHU A;  4U6Z A;  4A6V A;  2BHB A;  2MAT A;  2BH3 A;  1R58 A;  2BWT A;  4FLI A;  3S6B A;  5CDE A;  2Q94 A;  3BIP A;  1WLR A;  1XGO A;  3MR1 A;  3MX6 A;  4ZWU A;  4U76 A;  2BWU A;  4IKU A;  1YJ3 A;  1YW8 A;  1C21 A;  5CNX A;  1YW9 A;  1KQ0 A;  3PKE A;  1BOA A;  4IKS A;  1WL9 A;  2V3Z A;  2ZSG A;  3IU9 A;  2NQ6 A;  4R60 A;  1QXZ A;  2EA2 A;  4IU6 A;  1XGN A;  4S2T P;  2GG2 A;  2V6C A;  2G6P A;  4FLL A;  1WN1 A;  2BWY A;  3IU7 A;  2GG3 A;  2B3K A;  2BHD A;  4IDY A;  4FO8 A;  4MAT A;  2Q96 A;  4RZZ A;  2P9A A;  2GG0 A;  3D27 A;  4U6C A;  2BWW A;  4A6W A;  2V3X A;  4IKT A;  2GZ5 A;  3FM3 A;  1PV9 A;  1WBQ A;  4S00 A;  2GGC A;  3FMR A;  3PKC A;  4ZNG A;  4EGE A;  4FO7 A;  1W7V A;  3BIQ A;  4JUQ A;  1WKM A;  1B6A A;  4KM3 A;  2EVM A;  4IEC A;  1XGS A;  3PKD A;  1A16 A;  4RGZ 1;  4Z7M A;  2P98 A;  2NQ7 A;  3PKB A;  2GU6 A;  1CHM A;  2GG8 A;  2EVC A;  1N51 A;  4PV4 A;  3L7G A;  2BWV A;  1XGM A;  2GA2 A;  3TB5 A;  1M35 A;  1WY2 A;  3CB5 A;  4S01 A;  3IG4 A;  5CDL A;  5FCH A;  2Q95 A;  2BHA A;  3PKA A;  3CTZ A;  2IW2 A;  3RVA A;  1QXW A;  2GU4 A;  3CB6 A;  2EVO A;  2GG5 A;  5JFR A;  1C23 A;  4U75 A;  2BWS A;  1BN5 A;  2EA4 A;  2BN7 A;  1Y1N A;  3IU8 A;  2Q92 A;  4U6W A;  4IF7 A;  2V3Y A;  1JAW A;  2HOW A;  4U6E A;  1YW7 A;  4FUK A;  1O0X A;  5CDV A;  2Q8K A;  4U71 A;  2OKN A;  2GU7 A;  4U6J A;  1R5H A;  1QXY A;  4ZWP A;  2GGB A;  5E5B A;  5FCF A;  1KQ9 A;  2Q93 A;  2GG9 A;  4S2R P;  4U73 A;  4B28 A;  2GTX A;  2BHC A;  1C22 A;  4QR8 A;  4IKR A;  4ZWO A;  5D6E A;  4IPA A;  3BIT A;  1W2M A;  4OOK A;  5CE6 A;  4RZY A;  1B59 A;  1MAT A;  1XNZ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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