3IU8A

M. tuberculosis methionine aminopeptidase with ni inhibitor t03
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu8A01
1WKMA 2GU6A 2BWXA 2GU4A 1R5GA 4U71A 4ZWUA 2GG7A 3FMRA 4MATA 3S6BA 2BWYA 4U6ZA 2V3ZA 2Q93A 3PKBA 5D6FA 3L7GA 4IKUA 2V3XA 1XGOA 4A6WA 2GG0A 2BWVA 5E5BA 4FLJA 2Q92A 5FCFA 1QXYA 1WL9A 4EGEA 1BOAA 1KP0A 1WL6A 3FM3A 4U70A 1YVMA 4S2RP 4IF7A 2V6CA 4IKTA 1QXZA 2GG3A 1W7VA 3PKDA 4U6EA 2EA4A 1C24A 1WY2A 3FMQA 2P98A 4PNCA 2P9AA 1R5HA 2GG5A 2BH3A 1B59A 4IKRA 3MR1A 3TAVA 2NQ6A 2BB7A 3CB6A 1Y1NA 4S2TP 2B3HA 4A6VA 1XNZA 4HXXA 4IECA 3L24A 3PKAA 2BN7A 4ZWOA 4U69A 2GG9A 3MX6A 4FLIA 4IU6A 4OOKA 1WBQA 2Q94A 4U6CA 2P99A 3RORA 3CB5A 3BIPA 2GG2A 4IKSA 2BWTA 1MATA 2EVCA 2Q95A 3RVAA 4FO7A 5CDEA 2BHBA 4KM3A 2GGCA 5CLSA 4QR8A 2EVOA 1B6AA 4ZNGA 2GA2A 1JAWA 4ZWPA 1KQ9A 4FO8A 2EVMA 1YW7A 1W2MA 2GTXA 1A16A 1CHMA 3PKEA 4RZZA 2BHCA 4FLLA 5FCHA 1C23A 2BHDA 3PKCA 2BHAA 3IU8A 1M35A 4U76A 4R60A 1QZYA 3BITA 4S00A 1YW8A 2NQ7A 2GG8A 3TB5A 1YW9A 2V3YA 2EA2A 2MATA 2Q96A 4U6JA 4U73A 2HOWA 2IW2A 3IU9A 2ADUA 1WN1A 3BIQA 3CTZA 1R58A 4RZYA 2BWWA 5CNXA 2OKNA 2B3LA 4B28A 2GZ5A 5CE6A 1C27A 4U6WA 4JUQA 1O0XA 1XGMA 2DFIA 3D27A 1N51A 4RGZ1 2G6PA 5JFRA 4Z7MA 4IPAA 4FKCA 3IU7A 2BWUA 3IG4A 1BN5A 2OAZA 4PV4A 1C22A 1XGSA 1YJ3A 2BWSA 5JHUA 1PV9A 2GGBA 1C21A 3MATA 5D6EA 3Q6DA 2Q8KA 2ZSGA 5CIKA 4IDYA 1QXWA 4FUKA 4S01A 5CDLA 1XGNA 2B3KA 2GU7A 4U1BA 5JI6A 1KQ0A 4U75A 2GU5A 4FLKA 5CDVA 1WLRA
chains in the Genus database with same CATH superfamily
1WKMA 2GU6A 2BWXA 2GU4A 1R5GA 4U71A 4ZWUA 2GG7A 3FMRA 4MATA 3S6BA 2BWYA 4U6ZA 2V3ZA 2Q93A 3PKBA 5D6FA 3L7GA 4IKUA 2V3XA 1XGOA 4A6WA 2GG0A 2BWVA 5E5BA 4FLJA 2Q92A 5FCFA 1QXYA 1WL9A 4EGEA 1BOAA 1KP0A 1WL6A 3FM3A 4U70A 1YVMA 4S2RP 4IF7A 2V6CA 4IKTA 1QXZA 2GG3A 1W7VA 3PKDA 4U6EA 2EA4A 1C24A 1WY2A 3FMQA 2P98A 4PNCA 2P9AA 1R5HA 2GG5A 2BH3A 1B59A 4IKRA 3MR1A 3TAVA 2NQ6A 2BB7A 3CB6A 1Y1NA 4S2TP 2B3HA 4A6VA 1XNZA 4HXXA 4IECA 3L24A 3PKAA 2BN7A 4ZWOA 4U69A 2GG9A 3MX6A 4FLIA 4IU6A 4OOKA 1WBQA 2Q94A 4U6CA 2P99A 3RORA 3CB5A 3BIPA 2GG2A 4IKSA 2BWTA 1MATA 2EVCA 2Q95A 3RVAA 4FO7A 5CDEA 2BHBA 4KM3A 2GGCA 5CLSA 4QR8A 2EVOA 1B6AA 4ZNGA 2GA2A 1JAWA 4ZWPA 1KQ9A 4FO8A 2EVMA 1YW7A 1W2MA 2GTXA 1A16A 1CHMA 3PKEA 4RZZA 2BHCA 4FLLA 5FCHA 1C23A 2BHDA 3PKCA 2BHAA 3IU8A 1M35A 4U76A 4R60A 1QZYA 3BITA 4S00A 1YW8A 2NQ7A 2GG8A 3TB5A 1YW9A 2V3YA 2EA2A 2MATA 2Q96A 4U6JA 4U73A 2HOWA 2IW2A 3IU9A 2ADUA 1WN1A 3BIQA 3CTZA 1R58A 4RZYA 2BWWA 5CNXA 2OKNA 2B3LA 4B28A 2GZ5A 5CE6A 1C27A 4U6WA 4JUQA 1O0XA 1XGMA 2DFIA 3D27A 1N51A 4RGZ1 2G6PA 5JFRA 4Z7MA 4IPAA 4FKCA 3IU7A 2BWUA 3IG4A 1BN5A 2OAZA 4PV4A 1C22A 1XGSA 1YJ3A 2BWSA 5JHUA 1PV9A 2GGBA 1C21A 3MATA 5D6EA 3Q6DA 2Q8KA 2ZSGA 5CIKA 4IDYA 1QXWA 4FUKA 4S01A 5CDLA 1XGNA 2B3KA 2GU7A 4U1BA 5JI6A 1KQ0A 4U75A 2GU5A 4FLKA 5CDVA 1WLRA
chains in the Genus database with same CATH topology
1WKMA 2GU6A 2BWXA 2GU4A 1R5GA 4U71A 4ZWUA 2GG7A 3FMRA 4MATA 3S6BA 2BWYA 4U6ZA 2V3ZA 2Q93A 3PKBA 5D6FA 3L7GA 4IKUA 2V3XA 1XGOA 4A6WA 2GG0A 2BWVA 5E5BA 4FLJA 2Q92A 5FCFA 1QXYA 1WL9A 4EGEA 1BOAA 1KP0A 1WL6A 3FM3A 4U70A 1YVMA 4S2RP 4IF7A 2V6CA 4IKTA 1QXZA 2GG3A 1W7VA 3PKDA 4U6EA 2EA4A 1C24A 1WY2A 3FMQA 2P98A 4PNCA 2P9AA 1R5HA 2GG5A 2BH3A 1B59A 4IKRA 3MR1A 3TAVA 2NQ6A 2BB7A 3CB6A 1Y1NA 4S2TP 2B3HA 4A6VA 1XNZA 4HXXA 4IECA 3L24A 3PKAA 2BN7A 4ZWOA 4U69A 2GG9A 3MX6A 4FLIA 4IU6A 4OOKA 1WBQA 2Q94A 4U6CA 2P99A 3RORA 3CB5A 3BIPA 2GG2A 4IKSA 2BWTA 1MATA 2EVCA 2Q95A 3RVAA 4FO7A 5CDEA 2BHBA 4KM3A 2GGCA 5CLSA 4QR8A 2EVOA 1B6AA 4ZNGA 2GA2A 1JAWA 4ZWPA 1KQ9A 4FO8A 2EVMA 1YW7A 1W2MA 2GTXA 1A16A 1CHMA 3PKEA 4RZZA 2BHCA 4FLLA 5FCHA 1C23A 2BHDA 3PKCA 2BHAA 3IU8A 1M35A 4U76A 4R60A 1QZYA 3BITA 4S00A 1YW8A 2NQ7A 2GG8A 3TB5A 1YW9A 2V3YA 2EA2A 2MATA 2Q96A 4U6JA 4U73A 2HOWA 2IW2A 3IU9A 2ADUA 1WN1A 3BIQA 3CTZA 1R58A 4RZYA 2BWWA 5CNXA 2OKNA 2B3LA 4B28A 2GZ5A 5CE6A 1C27A 4U6WA 4JUQA 1O0XA 1XGMA 2DFIA 3D27A 1N51A 4RGZ1 2G6PA 5JFRA 4Z7MA 4IPAA 4FKCA 3IU7A 2BWUA 3IG4A 1BN5A 2OAZA 4PV4A 1C22A 1XGSA 1YJ3A 2BWSA 5JHUA 1PV9A 2GGBA 1C21A 3MATA 5D6EA 3Q6DA 2Q8KA 2ZSGA 5CIKA 4IDYA 1QXWA 4FUKA 4S01A 5CDLA 1XGNA 2B3KA 2GU7A 4U1BA 5JI6A 1KQ0A 4U75A 2GU5A 4FLKA 5CDVA 1WLRA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WKM A;  2GU6 A;  2BWX A;  2GU4 A;  1R5G A;  4U71 A;  4ZWU A;  2GG7 A;  3FMR A;  4MAT A;  3S6B A;  2BWY A;  4U6Z A;  2V3Z A;  2Q93 A;  3PKB A;  5D6F A;  3L7G A;  4IKU A;  2V3X A;  1XGO A;  4A6W A;  2GG0 A;  2BWV A;  5E5B A;  4FLJ A;  2Q92 A;  5FCF A;  1QXY A;  1WL9 A;  4EGE A;  1BOA A;  1KP0 A;  1WL6 A;  3FM3 A;  4U70 A;  1YVM A;  4S2R P;  4IF7 A;  2V6C A;  4IKT A;  1QXZ A;  2GG3 A;  1W7V A;  3PKD A;  4U6E A;  2EA4 A;  1C24 A;  1WY2 A;  3FMQ A;  2P98 A;  4PNC A;  2P9A A;  1R5H A;  2GG5 A;  2BH3 A;  1B59 A;  4IKR A;  3MR1 A;  3TAV A;  2NQ6 A;  2BB7 A;  3CB6 A;  1Y1N A;  4S2T P;  2B3H A;  4A6V A;  1XNZ A;  4HXX A;  4IEC A;  3L24 A;  3PKA A;  2BN7 A;  4ZWO A;  4U69 A;  2GG9 A;  3MX6 A;  4FLI A;  4IU6 A;  4OOK A;  1WBQ A;  2Q94 A;  4U6C A;  2P99 A;  3ROR A;  3CB5 A;  3BIP A;  2GG2 A;  4IKS A;  2BWT A;  1MAT A;  2EVC A;  2Q95 A;  3RVA A;  4FO7 A;  5CDE A;  2BHB A;  4KM3 A;  2GGC A;  5CLS A;  4QR8 A;  2EVO A;  1B6A A;  4ZNG A;  2GA2 A;  1JAW A;  4ZWP A;  1KQ9 A;  4FO8 A;  2EVM A;  1YW7 A;  1W2M A;  2GTX A;  1A16 A;  1CHM A;  3PKE A;  4RZZ A;  2BHC A;  4FLL A;  5FCH A;  1C23 A;  2BHD A;  3PKC A;  2BHA A;  3IU8 A;  1M35 A;  4U76 A;  4R60 A;  1QZY A;  3BIT A;  4S00 A;  1YW8 A;  2NQ7 A;  2GG8 A;  3TB5 A;  1YW9 A;  2V3Y A;  2EA2 A;  2MAT A;  2Q96 A;  4U6J A;  4U73 A;  2HOW A;  2IW2 A;  3IU9 A;  2ADU A;  1WN1 A;  3BIQ A;  3CTZ A;  1R58 A;  4RZY A;  2BWW A;  5CNX A;  2OKN A;  2B3L A;  4B28 A;  2GZ5 A;  5CE6 A;  1C27 A;  4U6W A;  4JUQ A;  1O0X A;  1XGM A;  2DFI A;  3D27 A;  1N51 A;  4RGZ 1;  2G6P A;  5JFR A;  4Z7M A;  4IPA A;  4FKC A;  3IU7 A;  2BWU A;  3IG4 A;  1BN5 A;  2OAZ A;  4PV4 A;  1C22 A;  1XGS A;  1YJ3 A;  2BWS A;  5JHU A;  1PV9 A;  2GGB A;  1C21 A;  3MAT A;  5D6E A;  3Q6D A;  2Q8K A;  2ZSG A;  5CIK A;  4IDY A;  1QXW A;  4FUK A;  4S01 A;  5CDL A;  1XGN A;  2B3K A;  2GU7 A;  4U1B A;  5JI6 A;  1KQ0 A;  4U75 A;  2GU5 A;  4FLK A;  5CDV A;  1WLR A; 
#chains in the Genus database with same CATH topology
 1WKM A;  2GU6 A;  2BWX A;  2GU4 A;  1R5G A;  4U71 A;  4ZWU A;  2GG7 A;  3FMR A;  4MAT A;  3S6B A;  2BWY A;  4U6Z A;  2V3Z A;  2Q93 A;  3PKB A;  5D6F A;  3L7G A;  4IKU A;  2V3X A;  1XGO A;  4A6W A;  2GG0 A;  2BWV A;  5E5B A;  4FLJ A;  2Q92 A;  5FCF A;  1QXY A;  1WL9 A;  4EGE A;  1BOA A;  1KP0 A;  1WL6 A;  3FM3 A;  4U70 A;  1YVM A;  4S2R P;  4IF7 A;  2V6C A;  4IKT A;  1QXZ A;  2GG3 A;  1W7V A;  3PKD A;  4U6E A;  2EA4 A;  1C24 A;  1WY2 A;  3FMQ A;  2P98 A;  4PNC A;  2P9A A;  1R5H A;  2GG5 A;  2BH3 A;  1B59 A;  4IKR A;  3MR1 A;  3TAV A;  2NQ6 A;  2BB7 A;  3CB6 A;  1Y1N A;  4S2T P;  2B3H A;  4A6V A;  1XNZ A;  4HXX A;  4IEC A;  3L24 A;  3PKA A;  2BN7 A;  4ZWO A;  4U69 A;  2GG9 A;  3MX6 A;  4FLI A;  4IU6 A;  4OOK A;  1WBQ A;  2Q94 A;  4U6C A;  2P99 A;  3ROR A;  3CB5 A;  3BIP A;  2GG2 A;  4IKS A;  2BWT A;  1MAT A;  2EVC A;  2Q95 A;  3RVA A;  4FO7 A;  5CDE A;  2BHB A;  4KM3 A;  2GGC A;  5CLS A;  4QR8 A;  2EVO A;  1B6A A;  4ZNG A;  2GA2 A;  1JAW A;  4ZWP A;  1KQ9 A;  4FO8 A;  2EVM A;  1YW7 A;  1W2M A;  2GTX A;  1A16 A;  1CHM A;  3PKE A;  4RZZ A;  2BHC A;  4FLL A;  5FCH A;  1C23 A;  2BHD A;  3PKC A;  2BHA A;  3IU8 A;  1M35 A;  4U76 A;  4R60 A;  1QZY A;  3BIT A;  4S00 A;  1YW8 A;  2NQ7 A;  2GG8 A;  3TB5 A;  1YW9 A;  2V3Y A;  2EA2 A;  2MAT A;  2Q96 A;  4U6J A;  4U73 A;  2HOW A;  2IW2 A;  3IU9 A;  2ADU A;  1WN1 A;  3BIQ A;  3CTZ A;  1R58 A;  4RZY A;  2BWW A;  5CNX A;  2OKN A;  2B3L A;  4B28 A;  2GZ5 A;  5CE6 A;  1C27 A;  4U6W A;  4JUQ A;  1O0X A;  1XGM A;  2DFI A;  3D27 A;  1N51 A;  4RGZ 1;  2G6P A;  5JFR A;  4Z7M A;  4IPA A;  4FKC A;  3IU7 A;  2BWU A;  3IG4 A;  1BN5 A;  2OAZ A;  4PV4 A;  1C22 A;  1XGS A;  1YJ3 A;  2BWS A;  5JHU A;  1PV9 A;  2GGB A;  1C21 A;  3MAT A;  5D6E A;  3Q6D A;  2Q8K A;  2ZSG A;  5CIK A;  4IDY A;  1QXW A;  4FUK A;  4S01 A;  5CDL A;  1XGN A;  2B3K A;  2GU7 A;  4U1B A;  5JI6 A;  1KQ0 A;  4U75 A;  2GU5 A;  4FLK A;  5CDV A;  1WLR A; 
#chains in the Genus database with same CATH homology
 1WKM A;  2GU6 A;  2BWX A;  2GU4 A;  1R5G A;  4U71 A;  4ZWU A;  2GG7 A;  3FMR A;  4MAT A;  3S6B A;  2BWY A;  4U6Z A;  2V3Z A;  2Q93 A;  3PKB A;  5D6F A;  3L7G A;  4IKU A;  2V3X A;  1XGO A;  4A6W A;  2GG0 A;  2BWV A;  5E5B A;  4FLJ A;  2Q92 A;  5FCF A;  1QXY A;  1WL9 A;  4EGE A;  1BOA A;  1KP0 A;  1WL6 A;  3FM3 A;  4U70 A;  1YVM A;  4S2R P;  4IF7 A;  2V6C A;  4IKT A;  1QXZ A;  2GG3 A;  1W7V A;  3PKD A;  4U6E A;  2EA4 A;  1C24 A;  1WY2 A;  3FMQ A;  2P98 A;  4PNC A;  2P9A A;  1R5H A;  2GG5 A;  2BH3 A;  1B59 A;  4IKR A;  3MR1 A;  3TAV A;  2NQ6 A;  2BB7 A;  3CB6 A;  1Y1N A;  4S2T P;  2B3H A;  4A6V A;  1XNZ A;  4HXX A;  4IEC A;  3L24 A;  3PKA A;  2BN7 A;  4ZWO A;  4U69 A;  2GG9 A;  3MX6 A;  4FLI A;  4IU6 A;  4OOK A;  1WBQ A;  2Q94 A;  4U6C A;  2P99 A;  3ROR A;  3CB5 A;  3BIP A;  2GG2 A;  4IKS A;  2BWT A;  1MAT A;  2EVC A;  2Q95 A;  3RVA A;  4FO7 A;  5CDE A;  2BHB A;  4KM3 A;  2GGC A;  5CLS A;  4QR8 A;  2EVO A;  1B6A A;  4ZNG A;  2GA2 A;  1JAW A;  4ZWP A;  1KQ9 A;  4FO8 A;  2EVM A;  1YW7 A;  1W2M A;  2GTX A;  1A16 A;  1CHM A;  3PKE A;  4RZZ A;  2BHC A;  4FLL A;  5FCH A;  1C23 A;  2BHD A;  3PKC A;  2BHA A;  3IU8 A;  1M35 A;  4U76 A;  4R60 A;  1QZY A;  3BIT A;  4S00 A;  1YW8 A;  2NQ7 A;  2GG8 A;  3TB5 A;  1YW9 A;  2V3Y A;  2EA2 A;  2MAT A;  2Q96 A;  4U6J A;  4U73 A;  2HOW A;  2IW2 A;  3IU9 A;  2ADU A;  1WN1 A;  3BIQ A;  3CTZ A;  1R58 A;  4RZY A;  2BWW A;  5CNX A;  2OKN A;  2B3L A;  4B28 A;  2GZ5 A;  5CE6 A;  1C27 A;  4U6W A;  4JUQ A;  1O0X A;  1XGM A;  2DFI A;  3D27 A;  1N51 A;  4RGZ 1;  2G6P A;  5JFR A;  4Z7M A;  4IPA A;  4FKC A;  3IU7 A;  2BWU A;  3IG4 A;  1BN5 A;  2OAZ A;  4PV4 A;  1C22 A;  1XGS A;  1YJ3 A;  2BWS A;  5JHU A;  1PV9 A;  2GGB A;  1C21 A;  3MAT A;  5D6E A;  3Q6D A;  2Q8K A;  2ZSG A;  5CIK A;  4IDY A;  1QXW A;  4FUK A;  4S01 A;  5CDL A;  1XGN A;  2B3K A;  2GU7 A;  4U1B A;  5JI6 A;  1KQ0 A;  4U75 A;  2GU5 A;  4FLK A;  5CDV A;  1WLR A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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