2ZSGA

Crystal structure of x-pro aminopeptidase from thermotoga maritima msb8
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
359
structure length
356
Chain Sequence
MDRSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVDFIDVLKKTVNDLKIKTIALEEERVSLSLFRRISSAFGDRKFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIGLEVHEGPAISFRNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILTTLPRSIFVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of X-Pro aminopeptidase from Thermotoga maritima MSB8
rcsb
molecule tags Hydrolase
source organism Thermotoga maritima
molecule keywords Aminopeptidase P, putative
total genus 124
structure length 356
sequence length 359
chains with identical sequence B
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2zsgA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2zsgA02
2BWSA 1BOAA 1C21A 3FMRA 1B59A 4U70A 4U6ZA 3PN9A 4MATA 3FMQA 4A6WA 4S01A 4U71A 5FCFA 1XGSA 3PEBA 5CDEA 1YW9A 2V6CA 2V3YA 4IKRA 4IU6A 1PV9A 5CIKA 3PKEA 3Q6DA 1WL9A 2BHDA 1Y1NA 2ADUA 4U6WA 5CE6A 2G6PA 1JAWA 4KM3A 2GG3A 2V3XA 2GU7A 1XGNA 2BWVA 2GGCA 2P9AA 1WL6A 4U73A 3MR1A 3MATA 1WN1A 1WKMA 2Q94A 1QZYA 1B6AA 2BWUA 2V3ZA 5CNXA 5FCHA 1R58A 5E2CA 4FO7A 1QXWA 4U76A 2OKNA 3IL0A 2ZSGA 4FLLA 2NQ6A 2Q96A 4U6JA 1XGMA 3CB6A 2Q92A 2GU4A 1R5HA 1A16A 1YW7A 2B3LA 5CDVA 2DFIA 4S2TP 3QOCA 3S6BA 1W7VA 4FO8A 2BHCA 1BN5A 1YW8A 2GG8A 4FLIA 1WBQA 4U69A 3FM3A 5E5BA 2BH3A 3IU9A 3I7MA 2BHAA 3OOOA 4FLKA 4IKUA 4U6CA 3BITA 2GU5A 1C27A 4PNCA 3CTZA 4PV4A 3RVAA 3IU8A 3BIPA 2P98A 4JUQA 4RZZA 2BB7A 2GTXA 1KP0A 4B28A 2B3HA 3TB5A 4QR8A 1CHMA 4FKCA 2EA4A 2GG0A 1C23A 2BHBA 3IG4A 4IPAA 1XNZA 2GU6A 2Q95A 4ZWUA 2GG5A 3CB5A 2OAZA 5D6EA 2GG7A 2GG9A 1YJ3A 3PKDA 4A6VA 3MX6A 1QXYA 2BN7A 4S2RP 3OVKA 1KQ9A 3BIQA 4IDYA 5JI6A 1KQ0A 3D27A 1YVMA 1C24A 1O0XA 2P99A 4R60A 2IW2A 2EVMA 4IF7A 2Q8KA 5CLSA 1WLRA 1QXZA 4ZNGA 4RGZ1 4S00A 3PKBA 2MATA 4U75A 1M35A 2EVCA 1XGOA 2GA2A 4IECA 4U1BA 1W2MA 1MATA 1R5GA 2EVOA 3RORA 2HOWA 2B3KA 2Q93A 2NQ7A 3PKAA 4FLJA 2GGBA 1N51A 4RZYA 4IKSA 5JHUA 2BWTA 3O5VA 4ZWOA 5JFRA 4FUKA 2GZ5A 1C22A 1WY2A 4U6EA 3L24A 4IKTA 2GG2A 3PKCA 4ZWPA 4HXXA 3TAVA 2BWWA 4OOKA 4Z7MA 3IU7A 4EGEA 2EA2A 2BWXA 5D6FA 3L7GA 5CDLA 2BWYA
chains in the Genus database with same CATH superfamily
2BWSA 1BOAA 1C21A 3FMRA 1B59A 4U70A 4U6ZA 3PN9A 4MATA 3FMQA 4A6WA 4S01A 4U71A 5FCFA 1XGSA 3PEBA 5CDEA 1YW9A 2V6CA 2V3YA 4IKRA 4IU6A 1PV9A 5CIKA 3PKEA 3Q6DA 1WL9A 2BHDA 1Y1NA 2ADUA 4U6WA 5CE6A 2G6PA 1JAWA 4KM3A 2GG3A 2V3XA 2GU7A 1XGNA 2BWVA 2GGCA 2P9AA 1WL6A 4U73A 3MR1A 3MATA 1WN1A 1WKMA 2Q94A 1QZYA 1B6AA 2BWUA 2V3ZA 5CNXA 5FCHA 1R58A 5E2CA 4FO7A 1QXWA 4U76A 2OKNA 3IL0A 2ZSGA 4FLLA 2NQ6A 2Q96A 4U6JA 1XGMA 3CB6A 2Q92A 2GU4A 1R5HA 1A16A 1YW7A 2B3LA 5CDVA 2DFIA 4S2TP 3QOCA 3S6BA 1W7VA 4FO8A 2BHCA 1BN5A 1YW8A 2GG8A 4FLIA 1WBQA 4U69A 3FM3A 5E5BA 2BH3A 3IU9A 3I7MA 2BHAA 3OOOA 4FLKA 4IKUA 4U6CA 3BITA 2GU5A 1C27A 4PNCA 3CTZA 4PV4A 3RVAA 3IU8A 3BIPA 2P98A 4JUQA 4RZZA 2BB7A 2GTXA 1KP0A 4B28A 2B3HA 3TB5A 4QR8A 1CHMA 4FKCA 2EA4A 2GG0A 1C23A 2BHBA 3IG4A 4IPAA 1XNZA 2GU6A 2Q95A 4ZWUA 2GG5A 3CB5A 2OAZA 5D6EA 2GG7A 2GG9A 1YJ3A 3PKDA 4A6VA 3MX6A 1QXYA 2BN7A 4S2RP 3OVKA 1KQ9A 3BIQA 4IDYA 5JI6A 1KQ0A 3D27A 1YVMA 1C24A 1O0XA 2P99A 4R60A 2IW2A 2EVMA 4IF7A 2Q8KA 5CLSA 1WLRA 1QXZA 4ZNGA 4RGZ1 4S00A 3PKBA 2MATA 4U75A 1M35A 2EVCA 1XGOA 2GA2A 4IECA 4U1BA 1W2MA 1MATA 1R5GA 2EVOA 3RORA 2HOWA 2B3KA 2Q93A 2NQ7A 3PKAA 4FLJA 2GGBA 1N51A 4RZYA 4IKSA 5JHUA 2BWTA 3O5VA 4ZWOA 5JFRA 4FUKA 2GZ5A 1C22A 1WY2A 4U6EA 3L24A 4IKTA 2GG2A 3PKCA 4ZWPA 4HXXA 3TAVA 2BWWA 4OOKA 4Z7MA 3IU7A 4EGEA 2EA2A 2BWXA 5D6FA 3L7GA 5CDLA 2BWYA
chains in the Genus database with same CATH topology
2BWSA 1BOAA 1C21A 3FMRA 1B59A 4U70A 4U6ZA 3PN9A 4MATA 3FMQA 4A6WA 4S01A 4U71A 5FCFA 1XGSA 3PEBA 5CDEA 1YW9A 2V6CA 2V3YA 4IKRA 4IU6A 1PV9A 5CIKA 3PKEA 3Q6DA 1WL9A 2BHDA 1Y1NA 2ADUA 4U6WA 5CE6A 2G6PA 1JAWA 4KM3A 2GG3A 2V3XA 2GU7A 1XGNA 2BWVA 2GGCA 2P9AA 1WL6A 4U73A 3MR1A 3MATA 1WN1A 1WKMA 2Q94A 1QZYA 1B6AA 2BWUA 2V3ZA 5CNXA 5FCHA 1R58A 5E2CA 4FO7A 1QXWA 4U76A 2OKNA 3IL0A 2ZSGA 4FLLA 2NQ6A 2Q96A 4U6JA 1XGMA 3CB6A 2Q92A 2GU4A 1R5HA 1A16A 1YW7A 2B3LA 5CDVA 2DFIA 4S2TP 3QOCA 3S6BA 1W7VA 4FO8A 2BHCA 1BN5A 1YW8A 2GG8A 4FLIA 1WBQA 4U69A 3FM3A 5E5BA 2BH3A 3IU9A 3I7MA 2BHAA 3OOOA 4FLKA 4IKUA 4U6CA 3BITA 2GU5A 1C27A 4PNCA 3CTZA 4PV4A 3RVAA 3IU8A 3BIPA 2P98A 4JUQA 4RZZA 2BB7A 2GTXA 1KP0A 4B28A 2B3HA 3TB5A 4QR8A 1CHMA 4FKCA 2EA4A 2GG0A 1C23A 2BHBA 3IG4A 4IPAA 1XNZA 2GU6A 2Q95A 4ZWUA 2GG5A 3CB5A 2OAZA 5D6EA 2GG7A 2GG9A 1YJ3A 3PKDA 4A6VA 3MX6A 1QXYA 2BN7A 4S2RP 3OVKA 1KQ9A 3BIQA 4IDYA 5JI6A 1KQ0A 3D27A 1YVMA 1C24A 1O0XA 2P99A 4R60A 2IW2A 2EVMA 4IF7A 2Q8KA 5CLSA 1WLRA 1QXZA 4ZNGA 4RGZ1 4S00A 3PKBA 2MATA 4U75A 1M35A 2EVCA 1XGOA 2GA2A 4IECA 4U1BA 1W2MA 1MATA 1R5GA 2EVOA 3RORA 2HOWA 2B3KA 2Q93A 2NQ7A 3PKAA 4FLJA 2GGBA 1N51A 4RZYA 4IKSA 5JHUA 2BWTA 3O5VA 4ZWOA 5JFRA 4FUKA 2GZ5A 1C22A 1WY2A 4U6EA 3L24A 4IKTA 2GG2A 3PKCA 4ZWPA 4HXXA 3TAVA 2BWWA 4OOKA 4Z7MA 3IU7A 4EGEA 2EA2A 2BWXA 5D6FA 3L7GA 5CDLA 2BWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BWS A;  1BOA A;  1C21 A;  3FMR A;  1B59 A;  4U70 A;  4U6Z A;  3PN9 A;  4MAT A;  3FMQ A;  4A6W A;  4S01 A;  4U71 A;  5FCF A;  1XGS A;  3PEB A;  5CDE A;  1YW9 A;  2V6C A;  2V3Y A;  4IKR A;  4IU6 A;  1PV9 A;  5CIK A;  3PKE A;  3Q6D A;  1WL9 A;  2BHD A;  1Y1N A;  2ADU A;  4U6W A;  5CE6 A;  2G6P A;  1JAW A;  4KM3 A;  2GG3 A;  2V3X A;  2GU7 A;  1XGN A;  2BWV A;  2GGC A;  2P9A A;  1WL6 A;  4U73 A;  3MR1 A;  3MAT A;  1WN1 A;  1WKM A;  2Q94 A;  1QZY A;  1B6A A;  2BWU A;  2V3Z A;  5CNX A;  5FCH A;  1R58 A;  5E2C A;  4FO7 A;  1QXW A;  4U76 A;  2OKN A;  3IL0 A;  2ZSG A;  4FLL A;  2NQ6 A;  2Q96 A;  4U6J A;  1XGM A;  3CB6 A;  2Q92 A;  2GU4 A;  1R5H A;  1A16 A;  1YW7 A;  2B3L A;  5CDV A;  2DFI A;  4S2T P;  3QOC A;  3S6B A;  1W7V A;  4FO8 A;  2BHC A;  1BN5 A;  1YW8 A;  2GG8 A;  4FLI A;  1WBQ A;  4U69 A;  3FM3 A;  5E5B A;  2BH3 A;  3IU9 A;  3I7M A;  2BHA A;  3OOO A;  4FLK A;  4IKU A;  4U6C A;  3BIT A;  2GU5 A;  1C27 A;  4PNC A;  3CTZ A;  4PV4 A;  3RVA A;  3IU8 A;  3BIP A;  2P98 A;  4JUQ A;  4RZZ A;  2BB7 A;  2GTX A;  1KP0 A;  4B28 A;  2B3H A;  3TB5 A;  4QR8 A;  1CHM A;  4FKC A;  2EA4 A;  2GG0 A;  1C23 A;  2BHB A;  3IG4 A;  4IPA A;  1XNZ A;  2GU6 A;  2Q95 A;  4ZWU A;  2GG5 A;  3CB5 A;  2OAZ A;  5D6E A;  2GG7 A;  2GG9 A;  1YJ3 A;  3PKD A;  4A6V A;  3MX6 A;  1QXY A;  2BN7 A;  4S2R P;  3OVK A;  1KQ9 A;  3BIQ A;  4IDY A;  5JI6 A;  1KQ0 A;  3D27 A;  1YVM A;  1C24 A;  1O0X A;  2P99 A;  4R60 A;  2IW2 A;  2EVM A;  4IF7 A;  2Q8K A;  5CLS A;  1WLR A;  1QXZ A;  4ZNG A;  4RGZ 1;  4S00 A;  3PKB A;  2MAT A;  4U75 A;  1M35 A;  2EVC A;  1XGO A;  2GA2 A;  4IEC A;  4U1B A;  1W2M A;  1MAT A;  1R5G A;  2EVO A;  3ROR A;  2HOW A;  2B3K A;  2Q93 A;  2NQ7 A;  3PKA A;  4FLJ A;  2GGB A;  1N51 A;  4RZY A;  4IKS A;  5JHU A;  2BWT A;  3O5V A;  4ZWO A;  5JFR A;  4FUK A;  2GZ5 A;  1C22 A;  1WY2 A;  4U6E A;  3L24 A;  4IKT A;  2GG2 A;  3PKC A;  4ZWP A;  4HXX A;  3TAV A;  2BWW A;  4OOK A;  4Z7M A;  3IU7 A;  4EGE A;  2EA2 A;  2BWX A;  5D6F A;  3L7G A;  5CDL A;  2BWY A; 
#chains in the Genus database with same CATH topology
 2BWS A;  1BOA A;  1C21 A;  3FMR A;  1B59 A;  4U70 A;  4U6Z A;  3PN9 A;  4MAT A;  3FMQ A;  4A6W A;  4S01 A;  4U71 A;  5FCF A;  1XGS A;  3PEB A;  5CDE A;  1YW9 A;  2V6C A;  2V3Y A;  4IKR A;  4IU6 A;  1PV9 A;  5CIK A;  3PKE A;  3Q6D A;  1WL9 A;  2BHD A;  1Y1N A;  2ADU A;  4U6W A;  5CE6 A;  2G6P A;  1JAW A;  4KM3 A;  2GG3 A;  2V3X A;  2GU7 A;  1XGN A;  2BWV A;  2GGC A;  2P9A A;  1WL6 A;  4U73 A;  3MR1 A;  3MAT A;  1WN1 A;  1WKM A;  2Q94 A;  1QZY A;  1B6A A;  2BWU A;  2V3Z A;  5CNX A;  5FCH A;  1R58 A;  5E2C A;  4FO7 A;  1QXW A;  4U76 A;  2OKN A;  3IL0 A;  2ZSG A;  4FLL A;  2NQ6 A;  2Q96 A;  4U6J A;  1XGM A;  3CB6 A;  2Q92 A;  2GU4 A;  1R5H A;  1A16 A;  1YW7 A;  2B3L A;  5CDV A;  2DFI A;  4S2T P;  3QOC A;  3S6B A;  1W7V A;  4FO8 A;  2BHC A;  1BN5 A;  1YW8 A;  2GG8 A;  4FLI A;  1WBQ A;  4U69 A;  3FM3 A;  5E5B A;  2BH3 A;  3IU9 A;  3I7M A;  2BHA A;  3OOO A;  4FLK A;  4IKU A;  4U6C A;  3BIT A;  2GU5 A;  1C27 A;  4PNC A;  3CTZ A;  4PV4 A;  3RVA A;  3IU8 A;  3BIP A;  2P98 A;  4JUQ A;  4RZZ A;  2BB7 A;  2GTX A;  1KP0 A;  4B28 A;  2B3H A;  3TB5 A;  4QR8 A;  1CHM A;  4FKC A;  2EA4 A;  2GG0 A;  1C23 A;  2BHB A;  3IG4 A;  4IPA A;  1XNZ A;  2GU6 A;  2Q95 A;  4ZWU A;  2GG5 A;  3CB5 A;  2OAZ A;  5D6E A;  2GG7 A;  2GG9 A;  1YJ3 A;  3PKD A;  4A6V A;  3MX6 A;  1QXY A;  2BN7 A;  4S2R P;  3OVK A;  1KQ9 A;  3BIQ A;  4IDY A;  5JI6 A;  1KQ0 A;  3D27 A;  1YVM A;  1C24 A;  1O0X A;  2P99 A;  4R60 A;  2IW2 A;  2EVM A;  4IF7 A;  2Q8K A;  5CLS A;  1WLR A;  1QXZ A;  4ZNG A;  4RGZ 1;  4S00 A;  3PKB A;  2MAT A;  4U75 A;  1M35 A;  2EVC A;  1XGO A;  2GA2 A;  4IEC A;  4U1B A;  1W2M A;  1MAT A;  1R5G A;  2EVO A;  3ROR A;  2HOW A;  2B3K A;  2Q93 A;  2NQ7 A;  3PKA A;  4FLJ A;  2GGB A;  1N51 A;  4RZY A;  4IKS A;  5JHU A;  2BWT A;  3O5V A;  4ZWO A;  5JFR A;  4FUK A;  2GZ5 A;  1C22 A;  1WY2 A;  4U6E A;  3L24 A;  4IKT A;  2GG2 A;  3PKC A;  4ZWP A;  4HXX A;  3TAV A;  2BWW A;  4OOK A;  4Z7M A;  3IU7 A;  4EGE A;  2EA2 A;  2BWX A;  5D6F A;  3L7G A;  5CDL A;  2BWY A; 
#chains in the Genus database with same CATH homology
 2BWS A;  1BOA A;  1C21 A;  3FMR A;  1B59 A;  4U70 A;  4U6Z A;  3PN9 A;  4MAT A;  3FMQ A;  4A6W A;  4S01 A;  4U71 A;  5FCF A;  1XGS A;  3PEB A;  5CDE A;  1YW9 A;  2V6C A;  2V3Y A;  4IKR A;  4IU6 A;  1PV9 A;  5CIK A;  3PKE A;  3Q6D A;  1WL9 A;  2BHD A;  1Y1N A;  2ADU A;  4U6W A;  5CE6 A;  2G6P A;  1JAW A;  4KM3 A;  2GG3 A;  2V3X A;  2GU7 A;  1XGN A;  2BWV A;  2GGC A;  2P9A A;  1WL6 A;  4U73 A;  3MR1 A;  3MAT A;  1WN1 A;  1WKM A;  2Q94 A;  1QZY A;  1B6A A;  2BWU A;  2V3Z A;  5CNX A;  5FCH A;  1R58 A;  5E2C A;  4FO7 A;  1QXW A;  4U76 A;  2OKN A;  3IL0 A;  2ZSG A;  4FLL A;  2NQ6 A;  2Q96 A;  4U6J A;  1XGM A;  3CB6 A;  2Q92 A;  2GU4 A;  1R5H A;  1A16 A;  1YW7 A;  2B3L A;  5CDV A;  2DFI A;  4S2T P;  3QOC A;  3S6B A;  1W7V A;  4FO8 A;  2BHC A;  1BN5 A;  1YW8 A;  2GG8 A;  4FLI A;  1WBQ A;  4U69 A;  3FM3 A;  5E5B A;  2BH3 A;  3IU9 A;  3I7M A;  2BHA A;  3OOO A;  4FLK A;  4IKU A;  4U6C A;  3BIT A;  2GU5 A;  1C27 A;  4PNC A;  3CTZ A;  4PV4 A;  3RVA A;  3IU8 A;  3BIP A;  2P98 A;  4JUQ A;  4RZZ A;  2BB7 A;  2GTX A;  1KP0 A;  4B28 A;  2B3H A;  3TB5 A;  4QR8 A;  1CHM A;  4FKC A;  2EA4 A;  2GG0 A;  1C23 A;  2BHB A;  3IG4 A;  4IPA A;  1XNZ A;  2GU6 A;  2Q95 A;  4ZWU A;  2GG5 A;  3CB5 A;  2OAZ A;  5D6E A;  2GG7 A;  2GG9 A;  1YJ3 A;  3PKD A;  4A6V A;  3MX6 A;  1QXY A;  2BN7 A;  4S2R P;  3OVK A;  1KQ9 A;  3BIQ A;  4IDY A;  5JI6 A;  1KQ0 A;  3D27 A;  1YVM A;  1C24 A;  1O0X A;  2P99 A;  4R60 A;  2IW2 A;  2EVM A;  4IF7 A;  2Q8K A;  5CLS A;  1WLR A;  1QXZ A;  4ZNG A;  4RGZ 1;  4S00 A;  3PKB A;  2MAT A;  4U75 A;  1M35 A;  2EVC A;  1XGO A;  2GA2 A;  4IEC A;  4U1B A;  1W2M A;  1MAT A;  1R5G A;  2EVO A;  3ROR A;  2HOW A;  2B3K A;  2Q93 A;  2NQ7 A;  3PKA A;  4FLJ A;  2GGB A;  1N51 A;  4RZY A;  4IKS A;  5JHU A;  2BWT A;  3O5V A;  4ZWO A;  5JFR A;  4FUK A;  2GZ5 A;  1C22 A;  1WY2 A;  4U6E A;  3L24 A;  4IKT A;  2GG2 A;  3PKC A;  4ZWP A;  4HXX A;  3TAV A;  2BWW A;  4OOK A;  4Z7M A;  3IU7 A;  4EGE A;  2EA2 A;  2BWX A;  5D6F A;  3L7G A;  5CDL A;  2BWY A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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