2ZSGA

Crystal structure of x-pro aminopeptidase from thermotoga maritima msb8
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
359
structure length
356
Chain Sequence
MDRSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVDFIDVLKKTVNDLKIKTIALEEERVSLSLFRRISSAFGDRKFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIGLEVHEGPAISFRNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILTTLPRSIFVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Aminopeptidase P, putative
publication title Crystal structure of X-Pro aminopeptidase from Thermotoga maritima MSB8
rcsb
source organism Thermotoga maritima
molecule tags Hydrolase
total genus 124
structure length 356
sequence length 359
chains with identical sequence B
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2zsgA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2zsgA02
4IKTA 4ZWPA 1KQ0A 1YVMA 2GU7A 4A6VA 1W7VA 3IU9A 3PKCA 4U71A 2BWTA 2GGCA 1YW9A 3BITA 2BWVA 4FO8A 1KQ9A 2IW2A 2G6PA 2Q96A 4HXXA 4Z7MA 2P98A 2GU4A 4JUQA 4U6EA 2BWYA 2V3YA 1A16A 3L24A 1PV9A 1R5HA 1C21A 2V3ZA 2B3HA 2Q92A 4EGEA 4U6ZA 2V6CA 4IDYA 2HOWA 2EVOA 4IKSA 4FLKA 4U1BA 1XGOA 2Q8KA 3I7MA 2MATA 3MX6A 1N51A 1Y1NA 2BWSA 4B28A 4IPAA 5JHUA 3IL0A 5CDLA 1QXYA 3PKDA 3OOOA 1WY2A 1B59A 4R60A 2P99A 2BHDA 4FLJA 1M35A 1WL6A 1WL9A 2BH3A 4KM3A 1O0XA 3FMQA 3IU7A 2BHCA 3CTZA 2Q95A 4S01A 3PKAA 2GTXA 2P9AA 4RZZA 3L7GA 2B3KA 2GZ5A 1QZYA 3BIQA 1QXWA 4A6WA 1BN5A 3PN9A 2B3LA 4IKUA 3MATA 1C27A 4RZYA 3FM3A 4FUKA 5CE6A 4U70A 5CLSA 1XGSA 4U6CA 2BHBA 2EA4A 1YJ3A 4U73A 2NQ6A 2BN7A 5CIKA 1CHMA 1WN1A 4QR8A 3IU8A 2BWWA 3BIPA 1W2MA 1C24A 3FMRA 3S6BA 4ZNGA 3QOCA 2OKNA 2BB7A 2NQ7A 3D27A 5FCFA 4OOKA 4U6JA 2GG3A 1YW7A 4S2TP 3RORA 4U6WA 5CNXA 4RGZ1 2GG0A 2GA2A 4S00A 2EVMA 1WLRA 2GG8A 1XGMA 2GU6A 2Q93A 3TB5A 4FKCA 3RVAA 1BOAA 4IECA 4FLLA 4ZWUA 4PV4A 3MR1A 2BWXA 5E2CA 3PKEA 4U69A 1B6AA 4IKRA 5E5BA 5CDVA 5D6FA 4FLIA 4U76A 5D6EA 2EVCA 2GG7A 3CB6A 2GG5A 4PNCA 5CDEA 4IF7A 2ZSGA 1R5GA 4IU6A 2OAZA 4U75A 2V3XA 2BHAA 2GG9A 3O5VA 2BWUA 2GGBA 1XGNA 4FO7A 1QXZA 3IG4A 1YW8A 2GU5A 5JFRA 2DFIA 2GG2A 3TAVA 1WBQA 1WKMA 1XNZA 2ADUA 3Q6DA 2Q94A 5JI6A 4ZWOA 1R58A 3PEBA 1C22A 2EA2A 3PKBA 1JAWA 4S2RP 4MATA 1MATA 1C23A 5FCHA 1KP0A 3OVKA 3CB5A
chains in the Genus database with same CATH superfamily
4IKTA 4ZWPA 1KQ0A 1YVMA 2GU7A 4A6VA 1W7VA 3IU9A 3PKCA 4U71A 2BWTA 2GGCA 1YW9A 3BITA 2BWVA 4FO8A 1KQ9A 2IW2A 2G6PA 2Q96A 4HXXA 4Z7MA 2P98A 2GU4A 4JUQA 4U6EA 2BWYA 2V3YA 1A16A 3L24A 1PV9A 1R5HA 1C21A 2V3ZA 2B3HA 2Q92A 4EGEA 4U6ZA 2V6CA 4IDYA 2HOWA 2EVOA 4IKSA 4FLKA 4U1BA 1XGOA 2Q8KA 3I7MA 2MATA 3MX6A 1N51A 1Y1NA 2BWSA 4B28A 4IPAA 5JHUA 3IL0A 5CDLA 1QXYA 3PKDA 3OOOA 1WY2A 1B59A 4R60A 2P99A 2BHDA 4FLJA 1M35A 1WL6A 1WL9A 2BH3A 4KM3A 1O0XA 3FMQA 3IU7A 2BHCA 3CTZA 2Q95A 4S01A 3PKAA 2GTXA 2P9AA 4RZZA 3L7GA 2B3KA 2GZ5A 1QZYA 3BIQA 1QXWA 4A6WA 1BN5A 3PN9A 2B3LA 4IKUA 3MATA 1C27A 4RZYA 3FM3A 4FUKA 5CE6A 4U70A 5CLSA 1XGSA 4U6CA 2BHBA 2EA4A 1YJ3A 4U73A 2NQ6A 2BN7A 5CIKA 1CHMA 1WN1A 4QR8A 3IU8A 2BWWA 3BIPA 1W2MA 1C24A 3FMRA 3S6BA 4ZNGA 3QOCA 2OKNA 2BB7A 2NQ7A 3D27A 5FCFA 4OOKA 4U6JA 2GG3A 1YW7A 4S2TP 3RORA 4U6WA 5CNXA 4RGZ1 2GG0A 2GA2A 4S00A 2EVMA 1WLRA 2GG8A 1XGMA 2GU6A 2Q93A 3TB5A 4FKCA 3RVAA 1BOAA 4IECA 4FLLA 4ZWUA 4PV4A 3MR1A 2BWXA 5E2CA 3PKEA 4U69A 1B6AA 4IKRA 5E5BA 5CDVA 5D6FA 4FLIA 4U76A 5D6EA 2EVCA 2GG7A 3CB6A 2GG5A 4PNCA 5CDEA 4IF7A 2ZSGA 1R5GA 4IU6A 2OAZA 4U75A 2V3XA 2BHAA 2GG9A 3O5VA 2BWUA 2GGBA 1XGNA 4FO7A 1QXZA 3IG4A 1YW8A 2GU5A 5JFRA 2DFIA 2GG2A 3TAVA 1WBQA 1WKMA 1XNZA 2ADUA 3Q6DA 2Q94A 5JI6A 4ZWOA 1R58A 3PEBA 1C22A 2EA2A 3PKBA 1JAWA 4S2RP 4MATA 1MATA 1C23A 5FCHA 1KP0A 3OVKA 3CB5A
chains in the Genus database with same CATH topology
4IKTA 4ZWPA 1KQ0A 1YVMA 2GU7A 4A6VA 1W7VA 3IU9A 3PKCA 4U71A 2BWTA 2GGCA 1YW9A 3BITA 2BWVA 4FO8A 1KQ9A 2IW2A 2G6PA 2Q96A 4HXXA 4Z7MA 2P98A 2GU4A 4JUQA 4U6EA 2BWYA 2V3YA 1A16A 3L24A 1PV9A 1R5HA 1C21A 2V3ZA 2B3HA 2Q92A 4EGEA 4U6ZA 2V6CA 4IDYA 2HOWA 2EVOA 4IKSA 4FLKA 4U1BA 1XGOA 2Q8KA 3I7MA 2MATA 3MX6A 1N51A 1Y1NA 2BWSA 4B28A 4IPAA 5JHUA 3IL0A 5CDLA 1QXYA 3PKDA 3OOOA 1WY2A 1B59A 4R60A 2P99A 2BHDA 4FLJA 1M35A 1WL6A 1WL9A 2BH3A 4KM3A 1O0XA 3FMQA 3IU7A 2BHCA 3CTZA 2Q95A 4S01A 3PKAA 2GTXA 2P9AA 4RZZA 3L7GA 2B3KA 2GZ5A 1QZYA 3BIQA 1QXWA 4A6WA 1BN5A 3PN9A 2B3LA 4IKUA 3MATA 1C27A 4RZYA 3FM3A 4FUKA 5CE6A 4U70A 5CLSA 1XGSA 4U6CA 2BHBA 2EA4A 1YJ3A 4U73A 2NQ6A 2BN7A 5CIKA 1CHMA 1WN1A 4QR8A 3IU8A 2BWWA 3BIPA 1W2MA 1C24A 3FMRA 3S6BA 4ZNGA 3QOCA 2OKNA 2BB7A 2NQ7A 3D27A 5FCFA 4OOKA 4U6JA 2GG3A 1YW7A 4S2TP 3RORA 4U6WA 5CNXA 4RGZ1 2GG0A 2GA2A 4S00A 2EVMA 1WLRA 2GG8A 1XGMA 2GU6A 2Q93A 3TB5A 4FKCA 3RVAA 1BOAA 4IECA 4FLLA 4ZWUA 4PV4A 3MR1A 2BWXA 5E2CA 3PKEA 4U69A 1B6AA 4IKRA 5E5BA 5CDVA 5D6FA 4FLIA 4U76A 5D6EA 2EVCA 2GG7A 3CB6A 2GG5A 4PNCA 5CDEA 4IF7A 2ZSGA 1R5GA 4IU6A 2OAZA 4U75A 2V3XA 2BHAA 2GG9A 3O5VA 2BWUA 2GGBA 1XGNA 4FO7A 1QXZA 3IG4A 1YW8A 2GU5A 5JFRA 2DFIA 2GG2A 3TAVA 1WBQA 1WKMA 1XNZA 2ADUA 3Q6DA 2Q94A 5JI6A 4ZWOA 1R58A 3PEBA 1C22A 2EA2A 3PKBA 1JAWA 4S2RP 4MATA 1MATA 1C23A 5FCHA 1KP0A 3OVKA 3CB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKT A;  4ZWP A;  1KQ0 A;  1YVM A;  2GU7 A;  4A6V A;  1W7V A;  3IU9 A;  3PKC A;  4U71 A;  2BWT A;  2GGC A;  1YW9 A;  3BIT A;  2BWV A;  4FO8 A;  1KQ9 A;  2IW2 A;  2G6P A;  2Q96 A;  4HXX A;  4Z7M A;  2P98 A;  2GU4 A;  4JUQ A;  4U6E A;  2BWY A;  2V3Y A;  1A16 A;  3L24 A;  1PV9 A;  1R5H A;  1C21 A;  2V3Z A;  2B3H A;  2Q92 A;  4EGE A;  4U6Z A;  2V6C A;  4IDY A;  2HOW A;  2EVO A;  4IKS A;  4FLK A;  4U1B A;  1XGO A;  2Q8K A;  3I7M A;  2MAT A;  3MX6 A;  1N51 A;  1Y1N A;  2BWS A;  4B28 A;  4IPA A;  5JHU A;  3IL0 A;  5CDL A;  1QXY A;  3PKD A;  3OOO A;  1WY2 A;  1B59 A;  4R60 A;  2P99 A;  2BHD A;  4FLJ A;  1M35 A;  1WL6 A;  1WL9 A;  2BH3 A;  4KM3 A;  1O0X A;  3FMQ A;  3IU7 A;  2BHC A;  3CTZ A;  2Q95 A;  4S01 A;  3PKA A;  2GTX A;  2P9A A;  4RZZ A;  3L7G A;  2B3K A;  2GZ5 A;  1QZY A;  3BIQ A;  1QXW A;  4A6W A;  1BN5 A;  3PN9 A;  2B3L A;  4IKU A;  3MAT A;  1C27 A;  4RZY A;  3FM3 A;  4FUK A;  5CE6 A;  4U70 A;  5CLS A;  1XGS A;  4U6C A;  2BHB A;  2EA4 A;  1YJ3 A;  4U73 A;  2NQ6 A;  2BN7 A;  5CIK A;  1CHM A;  1WN1 A;  4QR8 A;  3IU8 A;  2BWW A;  3BIP A;  1W2M A;  1C24 A;  3FMR A;  3S6B A;  4ZNG A;  3QOC A;  2OKN A;  2BB7 A;  2NQ7 A;  3D27 A;  5FCF A;  4OOK A;  4U6J A;  2GG3 A;  1YW7 A;  4S2T P;  3ROR A;  4U6W A;  5CNX A;  4RGZ 1;  2GG0 A;  2GA2 A;  4S00 A;  2EVM A;  1WLR A;  2GG8 A;  1XGM A;  2GU6 A;  2Q93 A;  3TB5 A;  4FKC A;  3RVA A;  1BOA A;  4IEC A;  4FLL A;  4ZWU A;  4PV4 A;  3MR1 A;  2BWX A;  5E2C A;  3PKE A;  4U69 A;  1B6A A;  4IKR A;  5E5B A;  5CDV A;  5D6F A;  4FLI A;  4U76 A;  5D6E A;  2EVC A;  2GG7 A;  3CB6 A;  2GG5 A;  4PNC A;  5CDE A;  4IF7 A;  2ZSG A;  1R5G A;  4IU6 A;  2OAZ A;  4U75 A;  2V3X A;  2BHA A;  2GG9 A;  3O5V A;  2BWU A;  2GGB A;  1XGN A;  4FO7 A;  1QXZ A;  3IG4 A;  1YW8 A;  2GU5 A;  5JFR A;  2DFI A;  2GG2 A;  3TAV A;  1WBQ A;  1WKM A;  1XNZ A;  2ADU A;  3Q6D A;  2Q94 A;  5JI6 A;  4ZWO A;  1R58 A;  3PEB A;  1C22 A;  2EA2 A;  3PKB A;  1JAW A;  4S2R P;  4MAT A;  1MAT A;  1C23 A;  5FCH A;  1KP0 A;  3OVK A;  3CB5 A; 
#chains in the Genus database with same CATH topology
 4IKT A;  4ZWP A;  1KQ0 A;  1YVM A;  2GU7 A;  4A6V A;  1W7V A;  3IU9 A;  3PKC A;  4U71 A;  2BWT A;  2GGC A;  1YW9 A;  3BIT A;  2BWV A;  4FO8 A;  1KQ9 A;  2IW2 A;  2G6P A;  2Q96 A;  4HXX A;  4Z7M A;  2P98 A;  2GU4 A;  4JUQ A;  4U6E A;  2BWY A;  2V3Y A;  1A16 A;  3L24 A;  1PV9 A;  1R5H A;  1C21 A;  2V3Z A;  2B3H A;  2Q92 A;  4EGE A;  4U6Z A;  2V6C A;  4IDY A;  2HOW A;  2EVO A;  4IKS A;  4FLK A;  4U1B A;  1XGO A;  2Q8K A;  3I7M A;  2MAT A;  3MX6 A;  1N51 A;  1Y1N A;  2BWS A;  4B28 A;  4IPA A;  5JHU A;  3IL0 A;  5CDL A;  1QXY A;  3PKD A;  3OOO A;  1WY2 A;  1B59 A;  4R60 A;  2P99 A;  2BHD A;  4FLJ A;  1M35 A;  1WL6 A;  1WL9 A;  2BH3 A;  4KM3 A;  1O0X A;  3FMQ A;  3IU7 A;  2BHC A;  3CTZ A;  2Q95 A;  4S01 A;  3PKA A;  2GTX A;  2P9A A;  4RZZ A;  3L7G A;  2B3K A;  2GZ5 A;  1QZY A;  3BIQ A;  1QXW A;  4A6W A;  1BN5 A;  3PN9 A;  2B3L A;  4IKU A;  3MAT A;  1C27 A;  4RZY A;  3FM3 A;  4FUK A;  5CE6 A;  4U70 A;  5CLS A;  1XGS A;  4U6C A;  2BHB A;  2EA4 A;  1YJ3 A;  4U73 A;  2NQ6 A;  2BN7 A;  5CIK A;  1CHM A;  1WN1 A;  4QR8 A;  3IU8 A;  2BWW A;  3BIP A;  1W2M A;  1C24 A;  3FMR A;  3S6B A;  4ZNG A;  3QOC A;  2OKN A;  2BB7 A;  2NQ7 A;  3D27 A;  5FCF A;  4OOK A;  4U6J A;  2GG3 A;  1YW7 A;  4S2T P;  3ROR A;  4U6W A;  5CNX A;  4RGZ 1;  2GG0 A;  2GA2 A;  4S00 A;  2EVM A;  1WLR A;  2GG8 A;  1XGM A;  2GU6 A;  2Q93 A;  3TB5 A;  4FKC A;  3RVA A;  1BOA A;  4IEC A;  4FLL A;  4ZWU A;  4PV4 A;  3MR1 A;  2BWX A;  5E2C A;  3PKE A;  4U69 A;  1B6A A;  4IKR A;  5E5B A;  5CDV A;  5D6F A;  4FLI A;  4U76 A;  5D6E A;  2EVC A;  2GG7 A;  3CB6 A;  2GG5 A;  4PNC A;  5CDE A;  4IF7 A;  2ZSG A;  1R5G A;  4IU6 A;  2OAZ A;  4U75 A;  2V3X A;  2BHA A;  2GG9 A;  3O5V A;  2BWU A;  2GGB A;  1XGN A;  4FO7 A;  1QXZ A;  3IG4 A;  1YW8 A;  2GU5 A;  5JFR A;  2DFI A;  2GG2 A;  3TAV A;  1WBQ A;  1WKM A;  1XNZ A;  2ADU A;  3Q6D A;  2Q94 A;  5JI6 A;  4ZWO A;  1R58 A;  3PEB A;  1C22 A;  2EA2 A;  3PKB A;  1JAW A;  4S2R P;  4MAT A;  1MAT A;  1C23 A;  5FCH A;  1KP0 A;  3OVK A;  3CB5 A; 
#chains in the Genus database with same CATH homology
 4IKT A;  4ZWP A;  1KQ0 A;  1YVM A;  2GU7 A;  4A6V A;  1W7V A;  3IU9 A;  3PKC A;  4U71 A;  2BWT A;  2GGC A;  1YW9 A;  3BIT A;  2BWV A;  4FO8 A;  1KQ9 A;  2IW2 A;  2G6P A;  2Q96 A;  4HXX A;  4Z7M A;  2P98 A;  2GU4 A;  4JUQ A;  4U6E A;  2BWY A;  2V3Y A;  1A16 A;  3L24 A;  1PV9 A;  1R5H A;  1C21 A;  2V3Z A;  2B3H A;  2Q92 A;  4EGE A;  4U6Z A;  2V6C A;  4IDY A;  2HOW A;  2EVO A;  4IKS A;  4FLK A;  4U1B A;  1XGO A;  2Q8K A;  3I7M A;  2MAT A;  3MX6 A;  1N51 A;  1Y1N A;  2BWS A;  4B28 A;  4IPA A;  5JHU A;  3IL0 A;  5CDL A;  1QXY A;  3PKD A;  3OOO A;  1WY2 A;  1B59 A;  4R60 A;  2P99 A;  2BHD A;  4FLJ A;  1M35 A;  1WL6 A;  1WL9 A;  2BH3 A;  4KM3 A;  1O0X A;  3FMQ A;  3IU7 A;  2BHC A;  3CTZ A;  2Q95 A;  4S01 A;  3PKA A;  2GTX A;  2P9A A;  4RZZ A;  3L7G A;  2B3K A;  2GZ5 A;  1QZY A;  3BIQ A;  1QXW A;  4A6W A;  1BN5 A;  3PN9 A;  2B3L A;  4IKU A;  3MAT A;  1C27 A;  4RZY A;  3FM3 A;  4FUK A;  5CE6 A;  4U70 A;  5CLS A;  1XGS A;  4U6C A;  2BHB A;  2EA4 A;  1YJ3 A;  4U73 A;  2NQ6 A;  2BN7 A;  5CIK A;  1CHM A;  1WN1 A;  4QR8 A;  3IU8 A;  2BWW A;  3BIP A;  1W2M A;  1C24 A;  3FMR A;  3S6B A;  4ZNG A;  3QOC A;  2OKN A;  2BB7 A;  2NQ7 A;  3D27 A;  5FCF A;  4OOK A;  4U6J A;  2GG3 A;  1YW7 A;  4S2T P;  3ROR A;  4U6W A;  5CNX A;  4RGZ 1;  2GG0 A;  2GA2 A;  4S00 A;  2EVM A;  1WLR A;  2GG8 A;  1XGM A;  2GU6 A;  2Q93 A;  3TB5 A;  4FKC A;  3RVA A;  1BOA A;  4IEC A;  4FLL A;  4ZWU A;  4PV4 A;  3MR1 A;  2BWX A;  5E2C A;  3PKE A;  4U69 A;  1B6A A;  4IKR A;  5E5B A;  5CDV A;  5D6F A;  4FLI A;  4U76 A;  5D6E A;  2EVC A;  2GG7 A;  3CB6 A;  2GG5 A;  4PNC A;  5CDE A;  4IF7 A;  2ZSG A;  1R5G A;  4IU6 A;  2OAZ A;  4U75 A;  2V3X A;  2BHA A;  2GG9 A;  3O5V A;  2BWU A;  2GGB A;  1XGN A;  4FO7 A;  1QXZ A;  3IG4 A;  1YW8 A;  2GU5 A;  5JFR A;  2DFI A;  2GG2 A;  3TAV A;  1WBQ A;  1WKM A;  1XNZ A;  2ADU A;  3Q6D A;  2Q94 A;  5JI6 A;  4ZWO A;  1R58 A;  3PEB A;  1C22 A;  2EA2 A;  3PKB A;  1JAW A;  4S2R P;  4MAT A;  1MAT A;  1C23 A;  5FCH A;  1KP0 A;  3OVK A;  3CB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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