2ZSGA

Crystal structure of x-pro aminopeptidase from thermotoga maritima msb8
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
359
structure length
356
Chain Sequence
MDRSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVDFIDVLKKTVNDLKIKTIALEEERVSLSLFRRISSAFGDRKFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIGLEVHEGPAISFRNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILTTLPRSIFVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of X-Pro aminopeptidase from Thermotoga maritima MSB8
rcsb
source organism Thermotoga maritima
molecule tags Hydrolase
molecule keywords Aminopeptidase P, putative
total genus 124
structure length 356
sequence length 359
chains with identical sequence B
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2zsgA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2zsgA02
2GU4A 2V3XA 4IF7A 2GG9A 2Q8KA 1BOAA 1M35A 2GG3A 2IW2A 2Q95A 4IPAA 1QZYA 1B59A 1WBQA 3CTZA 4ZWUA 1QXZA 1C23A 1C22A 2EVCA 4Z7MA 4U6CA 2GGBA 2V6CA 2GA2A 2GG0A 5E5BA 2BWVA 4ZWOA 2BHCA 4IKRA 2BB7A 1C21A 1R58A 1Y1NA 4FKCA 2BN7A 2GU7A 3IU7A 1XNZA 5JFRA 2Q96A 1YW9A 1B6AA 5JI6A 1PV9A 2V3YA 1XGOA 2GG7A 4MATA 1R5HA 1WL6A 3CB6A 3QOCA 1WN1A 2GG5A 4IU6A 3PKDA 2P9AA 4A6WA 4FLLA 4RZYA 4ZNGA 4IKUA 1JAWA 3OVKA 2BWWA 2B3KA 3RORA 3D27A 4U73A 1WKMA 3I7MA 1N51A 4PNCA 1YVMA 3BIQA 2GG8A 5FCHA 3IU9A 4IKTA 5D6FA 1W2MA 4R60A 3PKEA 1XGMA 4QR8A 1MATA 1WL9A 2EA4A 4IDYA 1YW8A 2BWTA 3Q6DA 1R5GA 4PV4A 2GZ5A 3FM3A 3RVAA 4U76A 5FCFA 2NQ6A 1WLRA 4FLKA 2P98A 4HXXA 3S6BA 2BHDA 4U6JA 2Q94A 1QXYA 1YW7A 4S2TP 2GU5A 4IECA 2HOWA 5CDVA 4U1BA 2Q93A 2BWSA 5CNXA 4RZZA 3IG4A 4KM3A 1KQ9A 1O0XA 2G6PA 2BWXA 2B3HA 4U6WA 2B3LA 2BWYA 1QXWA 2P99A 4RGZ1 2GGCA 5CDLA 1C27A 2GTXA 1BN5A 2BHBA 4A6VA 4S2RP 2GU6A 1XGNA 4U75A 4U71A 2BH3A 2OAZA 4FO7A 3L7GA 3IL0A 3MR1A 4JUQA 3TAVA 4U70A 1YJ3A 5D6EA 5CDEA 3FMRA 4U6ZA 4FLIA 2BWUA 4S01A 2EA2A 3MX6A 3PN9A 1A16A 3IU8A 2EVOA 4FLJA 3OOOA 4S00A 3BITA 3BIPA 4EGEA 4FO8A 4OOKA 2V3ZA 2GG2A 5E2CA 3O5VA 1WY2A 2ZSGA 4IKSA 3PKCA 1KP0A 4ZWPA 3CB5A 3PEBA 4U69A 3MATA 2BHAA 3PKAA 1W7VA 3TB5A 3L24A 5CIKA 2DFIA 1XGSA 2NQ7A 5CE6A 4FUKA 4U6EA 5CLSA 3FMQA 1CHMA 5JHUA 4B28A 2Q92A 3PKBA 1C24A 2OKNA 2MATA 1KQ0A 2ADUA 2EVMA
chains in the Genus database with same CATH superfamily
2GU4A 2V3XA 4IF7A 2GG9A 2Q8KA 1BOAA 1M35A 2GG3A 2IW2A 2Q95A 4IPAA 1QZYA 1B59A 1WBQA 3CTZA 4ZWUA 1QXZA 1C23A 1C22A 2EVCA 4Z7MA 4U6CA 2GGBA 2V6CA 2GA2A 2GG0A 5E5BA 2BWVA 4ZWOA 2BHCA 4IKRA 2BB7A 1C21A 1R58A 1Y1NA 4FKCA 2BN7A 2GU7A 3IU7A 1XNZA 5JFRA 2Q96A 1YW9A 1B6AA 5JI6A 1PV9A 2V3YA 1XGOA 2GG7A 4MATA 1R5HA 1WL6A 3CB6A 3QOCA 1WN1A 2GG5A 4IU6A 3PKDA 2P9AA 4A6WA 4FLLA 4RZYA 4ZNGA 4IKUA 1JAWA 3OVKA 2BWWA 2B3KA 3RORA 3D27A 4U73A 1WKMA 3I7MA 1N51A 4PNCA 1YVMA 3BIQA 2GG8A 5FCHA 3IU9A 4IKTA 5D6FA 1W2MA 4R60A 3PKEA 1XGMA 4QR8A 1MATA 1WL9A 2EA4A 4IDYA 1YW8A 2BWTA 3Q6DA 1R5GA 4PV4A 2GZ5A 3FM3A 3RVAA 4U76A 5FCFA 2NQ6A 1WLRA 4FLKA 2P98A 4HXXA 3S6BA 2BHDA 4U6JA 2Q94A 1QXYA 1YW7A 4S2TP 2GU5A 4IECA 2HOWA 5CDVA 4U1BA 2Q93A 2BWSA 5CNXA 4RZZA 3IG4A 4KM3A 1KQ9A 1O0XA 2G6PA 2BWXA 2B3HA 4U6WA 2B3LA 2BWYA 1QXWA 2P99A 4RGZ1 2GGCA 5CDLA 1C27A 2GTXA 1BN5A 2BHBA 4A6VA 4S2RP 2GU6A 1XGNA 4U75A 4U71A 2BH3A 2OAZA 4FO7A 3L7GA 3IL0A 3MR1A 4JUQA 3TAVA 4U70A 1YJ3A 5D6EA 5CDEA 3FMRA 4U6ZA 4FLIA 2BWUA 4S01A 2EA2A 3MX6A 3PN9A 1A16A 3IU8A 2EVOA 4FLJA 3OOOA 4S00A 3BITA 3BIPA 4EGEA 4FO8A 4OOKA 2V3ZA 2GG2A 5E2CA 3O5VA 1WY2A 2ZSGA 4IKSA 3PKCA 1KP0A 4ZWPA 3CB5A 3PEBA 4U69A 3MATA 2BHAA 3PKAA 1W7VA 3TB5A 3L24A 5CIKA 2DFIA 1XGSA 2NQ7A 5CE6A 4FUKA 4U6EA 5CLSA 3FMQA 1CHMA 5JHUA 4B28A 2Q92A 3PKBA 1C24A 2OKNA 2MATA 1KQ0A 2ADUA 2EVMA
chains in the Genus database with same CATH topology
2GU4A 2V3XA 4IF7A 2GG9A 2Q8KA 1BOAA 1M35A 2GG3A 2IW2A 2Q95A 4IPAA 1QZYA 1B59A 1WBQA 3CTZA 4ZWUA 1QXZA 1C23A 1C22A 2EVCA 4Z7MA 4U6CA 2GGBA 2V6CA 2GA2A 2GG0A 5E5BA 2BWVA 4ZWOA 2BHCA 4IKRA 2BB7A 1C21A 1R58A 1Y1NA 4FKCA 2BN7A 2GU7A 3IU7A 1XNZA 5JFRA 2Q96A 1YW9A 1B6AA 5JI6A 1PV9A 2V3YA 1XGOA 2GG7A 4MATA 1R5HA 1WL6A 3CB6A 3QOCA 1WN1A 2GG5A 4IU6A 3PKDA 2P9AA 4A6WA 4FLLA 4RZYA 4ZNGA 4IKUA 1JAWA 3OVKA 2BWWA 2B3KA 3RORA 3D27A 4U73A 1WKMA 3I7MA 1N51A 4PNCA 1YVMA 3BIQA 2GG8A 5FCHA 3IU9A 4IKTA 5D6FA 1W2MA 4R60A 3PKEA 1XGMA 4QR8A 1MATA 1WL9A 2EA4A 4IDYA 1YW8A 2BWTA 3Q6DA 1R5GA 4PV4A 2GZ5A 3FM3A 3RVAA 4U76A 5FCFA 2NQ6A 1WLRA 4FLKA 2P98A 4HXXA 3S6BA 2BHDA 4U6JA 2Q94A 1QXYA 1YW7A 4S2TP 2GU5A 4IECA 2HOWA 5CDVA 4U1BA 2Q93A 2BWSA 5CNXA 4RZZA 3IG4A 4KM3A 1KQ9A 1O0XA 2G6PA 2BWXA 2B3HA 4U6WA 2B3LA 2BWYA 1QXWA 2P99A 4RGZ1 2GGCA 5CDLA 1C27A 2GTXA 1BN5A 2BHBA 4A6VA 4S2RP 2GU6A 1XGNA 4U75A 4U71A 2BH3A 2OAZA 4FO7A 3L7GA 3IL0A 3MR1A 4JUQA 3TAVA 4U70A 1YJ3A 5D6EA 5CDEA 3FMRA 4U6ZA 4FLIA 2BWUA 4S01A 2EA2A 3MX6A 3PN9A 1A16A 3IU8A 2EVOA 4FLJA 3OOOA 4S00A 3BITA 3BIPA 4EGEA 4FO8A 4OOKA 2V3ZA 2GG2A 5E2CA 3O5VA 1WY2A 2ZSGA 4IKSA 3PKCA 1KP0A 4ZWPA 3CB5A 3PEBA 4U69A 3MATA 2BHAA 3PKAA 1W7VA 3TB5A 3L24A 5CIKA 2DFIA 1XGSA 2NQ7A 5CE6A 4FUKA 4U6EA 5CLSA 3FMQA 1CHMA 5JHUA 4B28A 2Q92A 3PKBA 1C24A 2OKNA 2MATA 1KQ0A 2ADUA 2EVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GU4 A;  2V3X A;  4IF7 A;  2GG9 A;  2Q8K A;  1BOA A;  1M35 A;  2GG3 A;  2IW2 A;  2Q95 A;  4IPA A;  1QZY A;  1B59 A;  1WBQ A;  3CTZ A;  4ZWU A;  1QXZ A;  1C23 A;  1C22 A;  2EVC A;  4Z7M A;  4U6C A;  2GGB A;  2V6C A;  2GA2 A;  2GG0 A;  5E5B A;  2BWV A;  4ZWO A;  2BHC A;  4IKR A;  2BB7 A;  1C21 A;  1R58 A;  1Y1N A;  4FKC A;  2BN7 A;  2GU7 A;  3IU7 A;  1XNZ A;  5JFR A;  2Q96 A;  1YW9 A;  1B6A A;  5JI6 A;  1PV9 A;  2V3Y A;  1XGO A;  2GG7 A;  4MAT A;  1R5H A;  1WL6 A;  3CB6 A;  3QOC A;  1WN1 A;  2GG5 A;  4IU6 A;  3PKD A;  2P9A A;  4A6W A;  4FLL A;  4RZY A;  4ZNG A;  4IKU A;  1JAW A;  3OVK A;  2BWW A;  2B3K A;  3ROR A;  3D27 A;  4U73 A;  1WKM A;  3I7M A;  1N51 A;  4PNC A;  1YVM A;  3BIQ A;  2GG8 A;  5FCH A;  3IU9 A;  4IKT A;  5D6F A;  1W2M A;  4R60 A;  3PKE A;  1XGM A;  4QR8 A;  1MAT A;  1WL9 A;  2EA4 A;  4IDY A;  1YW8 A;  2BWT A;  3Q6D A;  1R5G A;  4PV4 A;  2GZ5 A;  3FM3 A;  3RVA A;  4U76 A;  5FCF A;  2NQ6 A;  1WLR A;  4FLK A;  2P98 A;  4HXX A;  3S6B A;  2BHD A;  4U6J A;  2Q94 A;  1QXY A;  1YW7 A;  4S2T P;  2GU5 A;  4IEC A;  2HOW A;  5CDV A;  4U1B A;  2Q93 A;  2BWS A;  5CNX A;  4RZZ A;  3IG4 A;  4KM3 A;  1KQ9 A;  1O0X A;  2G6P A;  2BWX A;  2B3H A;  4U6W A;  2B3L A;  2BWY A;  1QXW A;  2P99 A;  4RGZ 1;  2GGC A;  5CDL A;  1C27 A;  2GTX A;  1BN5 A;  2BHB A;  4A6V A;  4S2R P;  2GU6 A;  1XGN A;  4U75 A;  4U71 A;  2BH3 A;  2OAZ A;  4FO7 A;  3L7G A;  3IL0 A;  3MR1 A;  4JUQ A;  3TAV A;  4U70 A;  1YJ3 A;  5D6E A;  5CDE A;  3FMR A;  4U6Z A;  4FLI A;  2BWU A;  4S01 A;  2EA2 A;  3MX6 A;  3PN9 A;  1A16 A;  3IU8 A;  2EVO A;  4FLJ A;  3OOO A;  4S00 A;  3BIT A;  3BIP A;  4EGE A;  4FO8 A;  4OOK A;  2V3Z A;  2GG2 A;  5E2C A;  3O5V A;  1WY2 A;  2ZSG A;  4IKS A;  3PKC A;  1KP0 A;  4ZWP A;  3CB5 A;  3PEB A;  4U69 A;  3MAT A;  2BHA A;  3PKA A;  1W7V A;  3TB5 A;  3L24 A;  5CIK A;  2DFI A;  1XGS A;  2NQ7 A;  5CE6 A;  4FUK A;  4U6E A;  5CLS A;  3FMQ A;  1CHM A;  5JHU A;  4B28 A;  2Q92 A;  3PKB A;  1C24 A;  2OKN A;  2MAT A;  1KQ0 A;  2ADU A;  2EVM A; 
#chains in the Genus database with same CATH topology
 2GU4 A;  2V3X A;  4IF7 A;  2GG9 A;  2Q8K A;  1BOA A;  1M35 A;  2GG3 A;  2IW2 A;  2Q95 A;  4IPA A;  1QZY A;  1B59 A;  1WBQ A;  3CTZ A;  4ZWU A;  1QXZ A;  1C23 A;  1C22 A;  2EVC A;  4Z7M A;  4U6C A;  2GGB A;  2V6C A;  2GA2 A;  2GG0 A;  5E5B A;  2BWV A;  4ZWO A;  2BHC A;  4IKR A;  2BB7 A;  1C21 A;  1R58 A;  1Y1N A;  4FKC A;  2BN7 A;  2GU7 A;  3IU7 A;  1XNZ A;  5JFR A;  2Q96 A;  1YW9 A;  1B6A A;  5JI6 A;  1PV9 A;  2V3Y A;  1XGO A;  2GG7 A;  4MAT A;  1R5H A;  1WL6 A;  3CB6 A;  3QOC A;  1WN1 A;  2GG5 A;  4IU6 A;  3PKD A;  2P9A A;  4A6W A;  4FLL A;  4RZY A;  4ZNG A;  4IKU A;  1JAW A;  3OVK A;  2BWW A;  2B3K A;  3ROR A;  3D27 A;  4U73 A;  1WKM A;  3I7M A;  1N51 A;  4PNC A;  1YVM A;  3BIQ A;  2GG8 A;  5FCH A;  3IU9 A;  4IKT A;  5D6F A;  1W2M A;  4R60 A;  3PKE A;  1XGM A;  4QR8 A;  1MAT A;  1WL9 A;  2EA4 A;  4IDY A;  1YW8 A;  2BWT A;  3Q6D A;  1R5G A;  4PV4 A;  2GZ5 A;  3FM3 A;  3RVA A;  4U76 A;  5FCF A;  2NQ6 A;  1WLR A;  4FLK A;  2P98 A;  4HXX A;  3S6B A;  2BHD A;  4U6J A;  2Q94 A;  1QXY A;  1YW7 A;  4S2T P;  2GU5 A;  4IEC A;  2HOW A;  5CDV A;  4U1B A;  2Q93 A;  2BWS A;  5CNX A;  4RZZ A;  3IG4 A;  4KM3 A;  1KQ9 A;  1O0X A;  2G6P A;  2BWX A;  2B3H A;  4U6W A;  2B3L A;  2BWY A;  1QXW A;  2P99 A;  4RGZ 1;  2GGC A;  5CDL A;  1C27 A;  2GTX A;  1BN5 A;  2BHB A;  4A6V A;  4S2R P;  2GU6 A;  1XGN A;  4U75 A;  4U71 A;  2BH3 A;  2OAZ A;  4FO7 A;  3L7G A;  3IL0 A;  3MR1 A;  4JUQ A;  3TAV A;  4U70 A;  1YJ3 A;  5D6E A;  5CDE A;  3FMR A;  4U6Z A;  4FLI A;  2BWU A;  4S01 A;  2EA2 A;  3MX6 A;  3PN9 A;  1A16 A;  3IU8 A;  2EVO A;  4FLJ A;  3OOO A;  4S00 A;  3BIT A;  3BIP A;  4EGE A;  4FO8 A;  4OOK A;  2V3Z A;  2GG2 A;  5E2C A;  3O5V A;  1WY2 A;  2ZSG A;  4IKS A;  3PKC A;  1KP0 A;  4ZWP A;  3CB5 A;  3PEB A;  4U69 A;  3MAT A;  2BHA A;  3PKA A;  1W7V A;  3TB5 A;  3L24 A;  5CIK A;  2DFI A;  1XGS A;  2NQ7 A;  5CE6 A;  4FUK A;  4U6E A;  5CLS A;  3FMQ A;  1CHM A;  5JHU A;  4B28 A;  2Q92 A;  3PKB A;  1C24 A;  2OKN A;  2MAT A;  1KQ0 A;  2ADU A;  2EVM A; 
#chains in the Genus database with same CATH homology
 2GU4 A;  2V3X A;  4IF7 A;  2GG9 A;  2Q8K A;  1BOA A;  1M35 A;  2GG3 A;  2IW2 A;  2Q95 A;  4IPA A;  1QZY A;  1B59 A;  1WBQ A;  3CTZ A;  4ZWU A;  1QXZ A;  1C23 A;  1C22 A;  2EVC A;  4Z7M A;  4U6C A;  2GGB A;  2V6C A;  2GA2 A;  2GG0 A;  5E5B A;  2BWV A;  4ZWO A;  2BHC A;  4IKR A;  2BB7 A;  1C21 A;  1R58 A;  1Y1N A;  4FKC A;  2BN7 A;  2GU7 A;  3IU7 A;  1XNZ A;  5JFR A;  2Q96 A;  1YW9 A;  1B6A A;  5JI6 A;  1PV9 A;  2V3Y A;  1XGO A;  2GG7 A;  4MAT A;  1R5H A;  1WL6 A;  3CB6 A;  3QOC A;  1WN1 A;  2GG5 A;  4IU6 A;  3PKD A;  2P9A A;  4A6W A;  4FLL A;  4RZY A;  4ZNG A;  4IKU A;  1JAW A;  3OVK A;  2BWW A;  2B3K A;  3ROR A;  3D27 A;  4U73 A;  1WKM A;  3I7M A;  1N51 A;  4PNC A;  1YVM A;  3BIQ A;  2GG8 A;  5FCH A;  3IU9 A;  4IKT A;  5D6F A;  1W2M A;  4R60 A;  3PKE A;  1XGM A;  4QR8 A;  1MAT A;  1WL9 A;  2EA4 A;  4IDY A;  1YW8 A;  2BWT A;  3Q6D A;  1R5G A;  4PV4 A;  2GZ5 A;  3FM3 A;  3RVA A;  4U76 A;  5FCF A;  2NQ6 A;  1WLR A;  4FLK A;  2P98 A;  4HXX A;  3S6B A;  2BHD A;  4U6J A;  2Q94 A;  1QXY A;  1YW7 A;  4S2T P;  2GU5 A;  4IEC A;  2HOW A;  5CDV A;  4U1B A;  2Q93 A;  2BWS A;  5CNX A;  4RZZ A;  3IG4 A;  4KM3 A;  1KQ9 A;  1O0X A;  2G6P A;  2BWX A;  2B3H A;  4U6W A;  2B3L A;  2BWY A;  1QXW A;  2P99 A;  4RGZ 1;  2GGC A;  5CDL A;  1C27 A;  2GTX A;  1BN5 A;  2BHB A;  4A6V A;  4S2R P;  2GU6 A;  1XGN A;  4U75 A;  4U71 A;  2BH3 A;  2OAZ A;  4FO7 A;  3L7G A;  3IL0 A;  3MR1 A;  4JUQ A;  3TAV A;  4U70 A;  1YJ3 A;  5D6E A;  5CDE A;  3FMR A;  4U6Z A;  4FLI A;  2BWU A;  4S01 A;  2EA2 A;  3MX6 A;  3PN9 A;  1A16 A;  3IU8 A;  2EVO A;  4FLJ A;  3OOO A;  4S00 A;  3BIT A;  3BIP A;  4EGE A;  4FO8 A;  4OOK A;  2V3Z A;  2GG2 A;  5E2C A;  3O5V A;  1WY2 A;  2ZSG A;  4IKS A;  3PKC A;  1KP0 A;  4ZWP A;  3CB5 A;  3PEB A;  4U69 A;  3MAT A;  2BHA A;  3PKA A;  1W7V A;  3TB5 A;  3L24 A;  5CIK A;  2DFI A;  1XGS A;  2NQ7 A;  5CE6 A;  4FUK A;  4U6E A;  5CLS A;  3FMQ A;  1CHM A;  5JHU A;  4B28 A;  2Q92 A;  3PKB A;  1C24 A;  2OKN A;  2MAT A;  1KQ0 A;  2ADU A;  2EVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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