2ZSGA

Crystal structure of x-pro aminopeptidase from thermotoga maritima msb8
Total Genus 124
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
124
sequence length
359
structure length
356
Chain Sequence
MDRSERLIQLISEEGIDAFLIMNIENSARASSVYFSGFTGSFSIILISENTRLLITDSRYTVQAKQETDFEVREVDFIDVLKKTVNDLKIKTIALEEERVSLSLFRRISSAFGDRKFIGIDDEVKQMRMVKDEGEIEKIKQAIEISERAFLETVQQIRAGMTEKEIAALLEYTMRKEGAEGVAFDTIVASGCRSALPHGKASDKVVERGDVIVIDFGATYENYCADITRVVSIGEPSDEVKEVHSIVLEAQERALKIAKAGVTGKLLDSVAREFIREKGYGEFFGHSLGHGIGLEVHEGPAISFRNDSPLPENVVFTVEPGIYLEGKFGIRIEEDVVLKEQGCEILTTLPRSIFVV
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Aminopeptidase P, putative
publication title Crystal structure of X-Pro aminopeptidase from Thermotoga maritima MSB8
rcsb
source organism Thermotoga maritima
total genus 124
structure length 356
sequence length 359
chains with identical sequence B
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2008-09-10

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2zsgA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2zsgA02
4Z7MA 1M35A 4ZWOA 2BHCA 2OKNA 3BIPA 4IDYA 3L7GA 4QR8A 3IL0A 2BWUA 5CDEA 3OVKA 2BWVA 3CB6A 2GG9A 2GG2A 2GU7A 4IKUA 2BWSA 4ZWUA 3MATA 1PV9A 1XNZA 5E2CA 4FUKA 1W2MA 4IECA 1R5HA 3TB5A 3PKCA 4ZWPA 1KP0A 2B3HA 3FM3A 1XGSA 1C22A 2BWXA 1XGMA 2B3KA 4IF7A 2V3XA 1WL6A 1QXZA 2ADUA 2BN7A 2OAZA 4ZNGA 3IG4A 3BIQA 1MATA 5CNXA 2HOWA 3FMQA 3IU7A 4U73A 4A6VA 2GGCA 3MR1A 1WN1A 1CHMA 1WL9A 1B6AA 2EVCA 2Q94A 3MX6A 1C27A 1JAWA 2GU6A 4PV4A 2NQ6A 4FLKA 2MATA 4U1BA 5JHUA 4U71A 1QXWA 4RGZ1 3CB5A 3L24A 5JFRA 4PNCA 2GG8A 2V6CA 2GG7A 4FO8A 1C21A 4U6EA 5CLSA 1WLRA 1R5GA 3OOOA 2EA2A 2DFIA 4HXXA 2GG0A 3RORA 4S2RP 4R60A 4EGEA 3BITA 1A16A 4IU6A 1KQ0A 1O0XA 4JUQA 2GU5A 4IKRA 2GZ5A 4S2TP 5CE6A 2BWWA 2ZSGA 2BWTA 5FCFA 3RVAA 1C24A 1XGOA 5CDLA 3FMRA 5D6FA 1BN5A 5JI6A 4RZYA 1QZYA 1B59A 5D6EA 2P98A 2NQ7A 1W7VA 2Q96A 3TAVA 1YW9A 3S6BA 3PN9A 1WBQA 4RZZA 5FCHA 3QOCA 4U6ZA 4FKCA 3PKEA 4U76A 4U6JA 3CTZA 2Q95A 2BHDA 3PEBA 3PKBA 4KM3A 2V3ZA 2P9AA 2EVOA 4FLJA 2GU4A 2EA4A 2BB7A 1Y1NA 4U6WA 1YVMA 2IW2A 4MATA 1YW7A 1QXYA 5E5BA 2Q8KA 4A6WA 4S00A 4IKSA 3O5VA 3IU9A 1WY2A 2EVMA 2P99A 1YW8A 2GGBA 2V3YA 1BOAA 3PKAA 2BWYA 1KQ9A 3PKDA 2Q93A 1R58A 2BHAA 4IPAA 2G6PA 2Q92A 4U75A 4U6CA 2BH3A 1WKMA 4U69A 1N51A 4S01A 3Q6DA 4FLLA 5CDVA 4OOKA 1XGNA 1C23A 4FO7A 1YJ3A 4IKTA 2BHBA 5CIKA 4U70A 3D27A 3I7MA 4B28A 3IU8A 2GG3A 2GTXA 2GA2A 2B3LA 2GG5A 4FLIA
chains in the Genus database with same CATH superfamily
4Z7MA 1M35A 4ZWOA 2BHCA 2OKNA 3BIPA 4IDYA 3L7GA 4QR8A 3IL0A 2BWUA 5CDEA 3OVKA 2BWVA 3CB6A 2GG9A 2GG2A 2GU7A 4IKUA 2BWSA 4ZWUA 3MATA 1PV9A 1XNZA 5E2CA 4FUKA 1W2MA 4IECA 1R5HA 3TB5A 3PKCA 4ZWPA 1KP0A 2B3HA 3FM3A 1XGSA 1C22A 2BWXA 1XGMA 2B3KA 4IF7A 2V3XA 1WL6A 1QXZA 2ADUA 2BN7A 2OAZA 4ZNGA 3IG4A 3BIQA 1MATA 5CNXA 2HOWA 3FMQA 3IU7A 4U73A 4A6VA 2GGCA 3MR1A 1WN1A 1CHMA 1WL9A 1B6AA 2EVCA 2Q94A 3MX6A 1C27A 1JAWA 2GU6A 4PV4A 2NQ6A 4FLKA 2MATA 4U1BA 5JHUA 4U71A 1QXWA 4RGZ1 3CB5A 3L24A 5JFRA 4PNCA 2GG8A 2V6CA 2GG7A 4FO8A 1C21A 4U6EA 5CLSA 1WLRA 1R5GA 3OOOA 2EA2A 2DFIA 4HXXA 2GG0A 3RORA 4S2RP 4R60A 4EGEA 3BITA 1A16A 4IU6A 1KQ0A 1O0XA 4JUQA 2GU5A 4IKRA 2GZ5A 4S2TP 5CE6A 2BWWA 2ZSGA 2BWTA 5FCFA 3RVAA 1C24A 1XGOA 5CDLA 3FMRA 5D6FA 1BN5A 5JI6A 4RZYA 1QZYA 1B59A 5D6EA 2P98A 2NQ7A 1W7VA 2Q96A 3TAVA 1YW9A 3S6BA 3PN9A 1WBQA 4RZZA 5FCHA 3QOCA 4U6ZA 4FKCA 3PKEA 4U76A 4U6JA 3CTZA 2Q95A 2BHDA 3PEBA 3PKBA 4KM3A 2V3ZA 2P9AA 2EVOA 4FLJA 2GU4A 2EA4A 2BB7A 1Y1NA 4U6WA 1YVMA 2IW2A 4MATA 1YW7A 1QXYA 5E5BA 2Q8KA 4A6WA 4S00A 4IKSA 3O5VA 3IU9A 1WY2A 2EVMA 2P99A 1YW8A 2GGBA 2V3YA 1BOAA 3PKAA 2BWYA 1KQ9A 3PKDA 2Q93A 1R58A 2BHAA 4IPAA 2G6PA 2Q92A 4U75A 4U6CA 2BH3A 1WKMA 4U69A 1N51A 4S01A 3Q6DA 4FLLA 5CDVA 4OOKA 1XGNA 1C23A 4FO7A 1YJ3A 4IKTA 2BHBA 5CIKA 4U70A 3D27A 3I7MA 4B28A 3IU8A 2GG3A 2GTXA 2GA2A 2B3LA 2GG5A 4FLIA
chains in the Genus database with same CATH topology
4Z7MA 1M35A 4ZWOA 2BHCA 2OKNA 3BIPA 4IDYA 3L7GA 4QR8A 3IL0A 2BWUA 5CDEA 3OVKA 2BWVA 3CB6A 2GG9A 2GG2A 2GU7A 4IKUA 2BWSA 4ZWUA 3MATA 1PV9A 1XNZA 5E2CA 4FUKA 1W2MA 4IECA 1R5HA 3TB5A 3PKCA 4ZWPA 1KP0A 2B3HA 3FM3A 1XGSA 1C22A 2BWXA 1XGMA 2B3KA 4IF7A 2V3XA 1WL6A 1QXZA 2ADUA 2BN7A 2OAZA 4ZNGA 3IG4A 3BIQA 1MATA 5CNXA 2HOWA 3FMQA 3IU7A 4U73A 4A6VA 2GGCA 3MR1A 1WN1A 1CHMA 1WL9A 1B6AA 2EVCA 2Q94A 3MX6A 1C27A 1JAWA 2GU6A 4PV4A 2NQ6A 4FLKA 2MATA 4U1BA 5JHUA 4U71A 1QXWA 4RGZ1 3CB5A 3L24A 5JFRA 4PNCA 2GG8A 2V6CA 2GG7A 4FO8A 1C21A 4U6EA 5CLSA 1WLRA 1R5GA 3OOOA 2EA2A 2DFIA 4HXXA 2GG0A 3RORA 4S2RP 4R60A 4EGEA 3BITA 1A16A 4IU6A 1KQ0A 1O0XA 4JUQA 2GU5A 4IKRA 2GZ5A 4S2TP 5CE6A 2BWWA 2ZSGA 2BWTA 5FCFA 3RVAA 1C24A 1XGOA 5CDLA 3FMRA 5D6FA 1BN5A 5JI6A 4RZYA 1QZYA 1B59A 5D6EA 2P98A 2NQ7A 1W7VA 2Q96A 3TAVA 1YW9A 3S6BA 3PN9A 1WBQA 4RZZA 5FCHA 3QOCA 4U6ZA 4FKCA 3PKEA 4U76A 4U6JA 3CTZA 2Q95A 2BHDA 3PEBA 3PKBA 4KM3A 2V3ZA 2P9AA 2EVOA 4FLJA 2GU4A 2EA4A 2BB7A 1Y1NA 4U6WA 1YVMA 2IW2A 4MATA 1YW7A 1QXYA 5E5BA 2Q8KA 4A6WA 4S00A 4IKSA 3O5VA 3IU9A 1WY2A 2EVMA 2P99A 1YW8A 2GGBA 2V3YA 1BOAA 3PKAA 2BWYA 1KQ9A 3PKDA 2Q93A 1R58A 2BHAA 4IPAA 2G6PA 2Q92A 4U75A 4U6CA 2BH3A 1WKMA 4U69A 1N51A 4S01A 3Q6DA 4FLLA 5CDVA 4OOKA 1XGNA 1C23A 4FO7A 1YJ3A 4IKTA 2BHBA 5CIKA 4U70A 3D27A 3I7MA 4B28A 3IU8A 2GG3A 2GTXA 2GA2A 2B3LA 2GG5A 4FLIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4Z7M A;  1M35 A;  4ZWO A;  2BHC A;  2OKN A;  3BIP A;  4IDY A;  3L7G A;  4QR8 A;  3IL0 A;  2BWU A;  5CDE A;  3OVK A;  2BWV A;  3CB6 A;  2GG9 A;  2GG2 A;  2GU7 A;  4IKU A;  2BWS A;  4ZWU A;  3MAT A;  1PV9 A;  1XNZ A;  5E2C A;  4FUK A;  1W2M A;  4IEC A;  1R5H A;  3TB5 A;  3PKC A;  4ZWP A;  1KP0 A;  2B3H A;  3FM3 A;  1XGS A;  1C22 A;  2BWX A;  1XGM A;  2B3K A;  4IF7 A;  2V3X A;  1WL6 A;  1QXZ A;  2ADU A;  2BN7 A;  2OAZ A;  4ZNG A;  3IG4 A;  3BIQ A;  1MAT A;  5CNX A;  2HOW A;  3FMQ A;  3IU7 A;  4U73 A;  4A6V A;  2GGC A;  3MR1 A;  1WN1 A;  1CHM A;  1WL9 A;  1B6A A;  2EVC A;  2Q94 A;  3MX6 A;  1C27 A;  1JAW A;  2GU6 A;  4PV4 A;  2NQ6 A;  4FLK A;  2MAT A;  4U1B A;  5JHU A;  4U71 A;  1QXW A;  4RGZ 1;  3CB5 A;  3L24 A;  5JFR A;  4PNC A;  2GG8 A;  2V6C A;  2GG7 A;  4FO8 A;  1C21 A;  4U6E A;  5CLS A;  1WLR A;  1R5G A;  3OOO A;  2EA2 A;  2DFI A;  4HXX A;  2GG0 A;  3ROR A;  4S2R P;  4R60 A;  4EGE A;  3BIT A;  1A16 A;  4IU6 A;  1KQ0 A;  1O0X A;  4JUQ A;  2GU5 A;  4IKR A;  2GZ5 A;  4S2T P;  5CE6 A;  2BWW A;  2ZSG A;  2BWT A;  5FCF A;  3RVA A;  1C24 A;  1XGO A;  5CDL A;  3FMR A;  5D6F A;  1BN5 A;  5JI6 A;  4RZY A;  1QZY A;  1B59 A;  5D6E A;  2P98 A;  2NQ7 A;  1W7V A;  2Q96 A;  3TAV A;  1YW9 A;  3S6B A;  3PN9 A;  1WBQ A;  4RZZ A;  5FCH A;  3QOC A;  4U6Z A;  4FKC A;  3PKE A;  4U76 A;  4U6J A;  3CTZ A;  2Q95 A;  2BHD A;  3PEB A;  3PKB A;  4KM3 A;  2V3Z A;  2P9A A;  2EVO A;  4FLJ A;  2GU4 A;  2EA4 A;  2BB7 A;  1Y1N A;  4U6W A;  1YVM A;  2IW2 A;  4MAT A;  1YW7 A;  1QXY A;  5E5B A;  2Q8K A;  4A6W A;  4S00 A;  4IKS A;  3O5V A;  3IU9 A;  1WY2 A;  2EVM A;  2P99 A;  1YW8 A;  2GGB A;  2V3Y A;  1BOA A;  3PKA A;  2BWY A;  1KQ9 A;  3PKD A;  2Q93 A;  1R58 A;  2BHA A;  4IPA A;  2G6P A;  2Q92 A;  4U75 A;  4U6C A;  2BH3 A;  1WKM A;  4U69 A;  1N51 A;  4S01 A;  3Q6D A;  4FLL A;  5CDV A;  4OOK A;  1XGN A;  1C23 A;  4FO7 A;  1YJ3 A;  4IKT A;  2BHB A;  5CIK A;  4U70 A;  3D27 A;  3I7M A;  4B28 A;  3IU8 A;  2GG3 A;  2GTX A;  2GA2 A;  2B3L A;  2GG5 A;  4FLI A; 
#chains in the Genus database with same CATH topology
 4Z7M A;  1M35 A;  4ZWO A;  2BHC A;  2OKN A;  3BIP A;  4IDY A;  3L7G A;  4QR8 A;  3IL0 A;  2BWU A;  5CDE A;  3OVK A;  2BWV A;  3CB6 A;  2GG9 A;  2GG2 A;  2GU7 A;  4IKU A;  2BWS A;  4ZWU A;  3MAT A;  1PV9 A;  1XNZ A;  5E2C A;  4FUK A;  1W2M A;  4IEC A;  1R5H A;  3TB5 A;  3PKC A;  4ZWP A;  1KP0 A;  2B3H A;  3FM3 A;  1XGS A;  1C22 A;  2BWX A;  1XGM A;  2B3K A;  4IF7 A;  2V3X A;  1WL6 A;  1QXZ A;  2ADU A;  2BN7 A;  2OAZ A;  4ZNG A;  3IG4 A;  3BIQ A;  1MAT A;  5CNX A;  2HOW A;  3FMQ A;  3IU7 A;  4U73 A;  4A6V A;  2GGC A;  3MR1 A;  1WN1 A;  1CHM A;  1WL9 A;  1B6A A;  2EVC A;  2Q94 A;  3MX6 A;  1C27 A;  1JAW A;  2GU6 A;  4PV4 A;  2NQ6 A;  4FLK A;  2MAT A;  4U1B A;  5JHU A;  4U71 A;  1QXW A;  4RGZ 1;  3CB5 A;  3L24 A;  5JFR A;  4PNC A;  2GG8 A;  2V6C A;  2GG7 A;  4FO8 A;  1C21 A;  4U6E A;  5CLS A;  1WLR A;  1R5G A;  3OOO A;  2EA2 A;  2DFI A;  4HXX A;  2GG0 A;  3ROR A;  4S2R P;  4R60 A;  4EGE A;  3BIT A;  1A16 A;  4IU6 A;  1KQ0 A;  1O0X A;  4JUQ A;  2GU5 A;  4IKR A;  2GZ5 A;  4S2T P;  5CE6 A;  2BWW A;  2ZSG A;  2BWT A;  5FCF A;  3RVA A;  1C24 A;  1XGO A;  5CDL A;  3FMR A;  5D6F A;  1BN5 A;  5JI6 A;  4RZY A;  1QZY A;  1B59 A;  5D6E A;  2P98 A;  2NQ7 A;  1W7V A;  2Q96 A;  3TAV A;  1YW9 A;  3S6B A;  3PN9 A;  1WBQ A;  4RZZ A;  5FCH A;  3QOC A;  4U6Z A;  4FKC A;  3PKE A;  4U76 A;  4U6J A;  3CTZ A;  2Q95 A;  2BHD A;  3PEB A;  3PKB A;  4KM3 A;  2V3Z A;  2P9A A;  2EVO A;  4FLJ A;  2GU4 A;  2EA4 A;  2BB7 A;  1Y1N A;  4U6W A;  1YVM A;  2IW2 A;  4MAT A;  1YW7 A;  1QXY A;  5E5B A;  2Q8K A;  4A6W A;  4S00 A;  4IKS A;  3O5V A;  3IU9 A;  1WY2 A;  2EVM A;  2P99 A;  1YW8 A;  2GGB A;  2V3Y A;  1BOA A;  3PKA A;  2BWY A;  1KQ9 A;  3PKD A;  2Q93 A;  1R58 A;  2BHA A;  4IPA A;  2G6P A;  2Q92 A;  4U75 A;  4U6C A;  2BH3 A;  1WKM A;  4U69 A;  1N51 A;  4S01 A;  3Q6D A;  4FLL A;  5CDV A;  4OOK A;  1XGN A;  1C23 A;  4FO7 A;  1YJ3 A;  4IKT A;  2BHB A;  5CIK A;  4U70 A;  3D27 A;  3I7M A;  4B28 A;  3IU8 A;  2GG3 A;  2GTX A;  2GA2 A;  2B3L A;  2GG5 A;  4FLI A; 
#chains in the Genus database with same CATH homology
 4Z7M A;  1M35 A;  4ZWO A;  2BHC A;  2OKN A;  3BIP A;  4IDY A;  3L7G A;  4QR8 A;  3IL0 A;  2BWU A;  5CDE A;  3OVK A;  2BWV A;  3CB6 A;  2GG9 A;  2GG2 A;  2GU7 A;  4IKU A;  2BWS A;  4ZWU A;  3MAT A;  1PV9 A;  1XNZ A;  5E2C A;  4FUK A;  1W2M A;  4IEC A;  1R5H A;  3TB5 A;  3PKC A;  4ZWP A;  1KP0 A;  2B3H A;  3FM3 A;  1XGS A;  1C22 A;  2BWX A;  1XGM A;  2B3K A;  4IF7 A;  2V3X A;  1WL6 A;  1QXZ A;  2ADU A;  2BN7 A;  2OAZ A;  4ZNG A;  3IG4 A;  3BIQ A;  1MAT A;  5CNX A;  2HOW A;  3FMQ A;  3IU7 A;  4U73 A;  4A6V A;  2GGC A;  3MR1 A;  1WN1 A;  1CHM A;  1WL9 A;  1B6A A;  2EVC A;  2Q94 A;  3MX6 A;  1C27 A;  1JAW A;  2GU6 A;  4PV4 A;  2NQ6 A;  4FLK A;  2MAT A;  4U1B A;  5JHU A;  4U71 A;  1QXW A;  4RGZ 1;  3CB5 A;  3L24 A;  5JFR A;  4PNC A;  2GG8 A;  2V6C A;  2GG7 A;  4FO8 A;  1C21 A;  4U6E A;  5CLS A;  1WLR A;  1R5G A;  3OOO A;  2EA2 A;  2DFI A;  4HXX A;  2GG0 A;  3ROR A;  4S2R P;  4R60 A;  4EGE A;  3BIT A;  1A16 A;  4IU6 A;  1KQ0 A;  1O0X A;  4JUQ A;  2GU5 A;  4IKR A;  2GZ5 A;  4S2T P;  5CE6 A;  2BWW A;  2ZSG A;  2BWT A;  5FCF A;  3RVA A;  1C24 A;  1XGO A;  5CDL A;  3FMR A;  5D6F A;  1BN5 A;  5JI6 A;  4RZY A;  1QZY A;  1B59 A;  5D6E A;  2P98 A;  2NQ7 A;  1W7V A;  2Q96 A;  3TAV A;  1YW9 A;  3S6B A;  3PN9 A;  1WBQ A;  4RZZ A;  5FCH A;  3QOC A;  4U6Z A;  4FKC A;  3PKE A;  4U76 A;  4U6J A;  3CTZ A;  2Q95 A;  2BHD A;  3PEB A;  3PKB A;  4KM3 A;  2V3Z A;  2P9A A;  2EVO A;  4FLJ A;  2GU4 A;  2EA4 A;  2BB7 A;  1Y1N A;  4U6W A;  1YVM A;  2IW2 A;  4MAT A;  1YW7 A;  1QXY A;  5E5B A;  2Q8K A;  4A6W A;  4S00 A;  4IKS A;  3O5V A;  3IU9 A;  1WY2 A;  2EVM A;  2P99 A;  1YW8 A;  2GGB A;  2V3Y A;  1BOA A;  3PKA A;  2BWY A;  1KQ9 A;  3PKD A;  2Q93 A;  1R58 A;  2BHA A;  4IPA A;  2G6P A;  2Q92 A;  4U75 A;  4U6C A;  2BH3 A;  1WKM A;  4U69 A;  1N51 A;  4S01 A;  3Q6D A;  4FLL A;  5CDV A;  4OOK A;  1XGN A;  1C23 A;  4FO7 A;  1YJ3 A;  4IKT A;  2BHB A;  5CIK A;  4U70 A;  3D27 A;  3I7M A;  4B28 A;  3IU8 A;  2GG3 A;  2GTX A;  2GA2 A;  2B3L A;  2GG5 A;  4FLI A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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