1O0XA

Crystal structure of methionine aminopeptidase (tm1478) from thermotoga maritima at 1.90 a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
249
structure length
249
Chain Sequence
MIRIKTPSEIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGYKYATCVSVNEEVVHGLPLKEKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGRELHEDPQIPNYGTPGTGVVLRKGMTLAIEPMVSEGDWRVVVKEDGWTAVTVDGSRCAHFEHTILITENGAEILTKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Thermotoga maritima
total genus 84
structure length 249
sequence length 249
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1o0xA00
1B6AA 1XGOA 3PKCA 1XGNA 2GG7A 2BHBA 3RVAA 1M35A 2BHAA 4U75A 2OAZA 1WY2A 1YW8A 2GTXA 5CLSA 1W7VA 3RORA 5CE6A 4U71A 1R5HA 1R58A 2P9AA 1QZYA 5FCFA 1C22A 1C27A 4ZWOA 3S6BA 1QXWA 5CDEA 2ADUA 2BWSA 4U6CA 2BN7A 4IKTA 4U70A 2Q94A 2EVCA 1YW7A 4A6VA 2BWTA 5JHUA 3BIPA 2Q92A 4B28A 1C21A 4IKRA 1JAWA 2GU5A 2GG8A 2P99A 1WL6A 4S00A 1WLRA 5CDLA 3TAVA 3MX6A 1B59A 2V3YA 2NQ6A 4PV4A 4RZYA 5D6EA 1A16A 3IU9A 4JUQA 2BWWA 1BOAA 2EA4A 2OKNA 4EGEA 5CNXA 1YVMA 4S2TP 1MATA 1QXZA 4OOKA 2BWUA 1QXYA 2HOWA 3PKBA 1BN5A 4Z7MA 5JI6A 4U73A 3IU8A 4S2RP 5E5BA 2BH3A 1C24A 3FMRA 4IKUA 1C23A 3FM3A 3PKEA 4IECA 1XGMA 2IW2A 2BWVA 4FO7A 2GG0A 2DFIA 3BITA 1PV9A 2NQ7A 2BWYA 4U69A 2V3ZA 2EVOA 3FMQA 5JFRA 1XNZA 4IKSA 3CTZA 4MATA 2B3HA 4R60A 1WBQA 5FCHA 4FLJA 4IU6A 4RGZ1 1N51A 4ZNGA 3L24A 2EA2A 4PNCA 1YW9A 1Y1NA 4U76A 2GU7A 2GG3A 3Q6DA 1O0XA 3CB5A 4HXXA 2BHDA 1WKMA 2Q96A 1R5GA 3BIQA 2B3KA 2BHCA 3TB5A 2ZSGA 4IF7A 2GZ5A 3PKAA 2EVMA 3IU7A 2GU6A 3PKDA 3D27A 2V6CA 4KM3A 3IG4A 2GGCA 4S01A 2Q8KA 1KP0A 4IDYA 5CDVA 2P98A 1CHMA 4ZWUA 4FUKA 1WL9A 4U6EA 2GA2A 1YJ3A 4U6JA 2GGBA 4ZWPA 2MATA 2V3XA 2GG5A 3MR1A 4FLIA 2GU4A 3L7GA 2GG2A 4IPAA 1WN1A 2B3LA 2BB7A 2BWXA 1XGSA 4FKCA 4FO8A 4QR8A 4U6WA 1W2MA 3CB6A 1KQ9A 2GG9A 3MATA 4FLLA 4A6WA 5CIKA 5D6FA 1KQ0A 2Q93A 4U6ZA 4FLKA 4U1BA 2G6PA 2Q95A 4RZZA
chains in the Genus database with same CATH superfamily
1B6AA 1XGOA 3PKCA 1XGNA 2GG7A 2BHBA 3RVAA 1M35A 2BHAA 4U75A 2OAZA 1WY2A 1YW8A 2GTXA 5CLSA 1W7VA 3RORA 5CE6A 4U71A 1R5HA 1R58A 2P9AA 1QZYA 5FCFA 1C22A 1C27A 4ZWOA 3S6BA 1QXWA 5CDEA 2ADUA 2BWSA 4U6CA 2BN7A 4IKTA 4U70A 2Q94A 2EVCA 1YW7A 4A6VA 2BWTA 5JHUA 3BIPA 2Q92A 4B28A 1C21A 4IKRA 1JAWA 2GU5A 2GG8A 2P99A 1WL6A 4S00A 1WLRA 5CDLA 3TAVA 3MX6A 1B59A 2V3YA 2NQ6A 4PV4A 4RZYA 5D6EA 1A16A 3IU9A 4JUQA 2BWWA 1BOAA 2EA4A 2OKNA 4EGEA 5CNXA 1YVMA 4S2TP 1MATA 1QXZA 4OOKA 2BWUA 1QXYA 2HOWA 3PKBA 1BN5A 4Z7MA 5JI6A 4U73A 3IU8A 4S2RP 5E5BA 2BH3A 1C24A 3FMRA 4IKUA 1C23A 3FM3A 3PKEA 4IECA 1XGMA 2IW2A 2BWVA 4FO7A 2GG0A 2DFIA 3BITA 1PV9A 2NQ7A 2BWYA 4U69A 2V3ZA 2EVOA 3FMQA 5JFRA 1XNZA 4IKSA 3CTZA 4MATA 2B3HA 4R60A 1WBQA 5FCHA 4FLJA 4IU6A 4RGZ1 1N51A 4ZNGA 3L24A 2EA2A 4PNCA 1YW9A 1Y1NA 4U76A 2GU7A 2GG3A 3Q6DA 1O0XA 3CB5A 4HXXA 2BHDA 1WKMA 2Q96A 1R5GA 3BIQA 2B3KA 2BHCA 3TB5A 2ZSGA 4IF7A 2GZ5A 3PKAA 2EVMA 3IU7A 2GU6A 3PKDA 3D27A 2V6CA 4KM3A 3IG4A 2GGCA 4S01A 2Q8KA 1KP0A 4IDYA 5CDVA 2P98A 1CHMA 4ZWUA 4FUKA 1WL9A 4U6EA 2GA2A 1YJ3A 4U6JA 2GGBA 4ZWPA 2MATA 2V3XA 2GG5A 3MR1A 4FLIA 2GU4A 3L7GA 2GG2A 4IPAA 1WN1A 2B3LA 2BB7A 2BWXA 1XGSA 4FKCA 4FO8A 4QR8A 4U6WA 1W2MA 3CB6A 1KQ9A 2GG9A 3MATA 4FLLA 4A6WA 5CIKA 5D6FA 1KQ0A 2Q93A 4U6ZA 4FLKA 4U1BA 2G6PA 2Q95A 4RZZA
chains in the Genus database with same CATH topology
1B6AA 1XGOA 3PKCA 1XGNA 2GG7A 2BHBA 3RVAA 1M35A 2BHAA 4U75A 2OAZA 1WY2A 1YW8A 2GTXA 5CLSA 1W7VA 3RORA 5CE6A 4U71A 1R5HA 1R58A 2P9AA 1QZYA 5FCFA 1C22A 1C27A 4ZWOA 3S6BA 1QXWA 5CDEA 2ADUA 2BWSA 4U6CA 2BN7A 4IKTA 4U70A 2Q94A 2EVCA 1YW7A 4A6VA 2BWTA 5JHUA 3BIPA 2Q92A 4B28A 1C21A 4IKRA 1JAWA 2GU5A 2GG8A 2P99A 1WL6A 4S00A 1WLRA 5CDLA 3TAVA 3MX6A 1B59A 2V3YA 2NQ6A 4PV4A 4RZYA 5D6EA 1A16A 3IU9A 4JUQA 2BWWA 1BOAA 2EA4A 2OKNA 4EGEA 5CNXA 1YVMA 4S2TP 1MATA 1QXZA 4OOKA 2BWUA 1QXYA 2HOWA 3PKBA 1BN5A 4Z7MA 5JI6A 4U73A 3IU8A 4S2RP 5E5BA 2BH3A 1C24A 3FMRA 4IKUA 1C23A 3FM3A 3PKEA 4IECA 1XGMA 2IW2A 2BWVA 4FO7A 2GG0A 2DFIA 3BITA 1PV9A 2NQ7A 2BWYA 4U69A 2V3ZA 2EVOA 3FMQA 5JFRA 1XNZA 4IKSA 3CTZA 4MATA 2B3HA 4R60A 1WBQA 5FCHA 4FLJA 4IU6A 4RGZ1 1N51A 4ZNGA 3L24A 2EA2A 4PNCA 1YW9A 1Y1NA 4U76A 2GU7A 2GG3A 3Q6DA 1O0XA 3CB5A 4HXXA 2BHDA 1WKMA 2Q96A 1R5GA 3BIQA 2B3KA 2BHCA 3TB5A 2ZSGA 4IF7A 2GZ5A 3PKAA 2EVMA 3IU7A 2GU6A 3PKDA 3D27A 2V6CA 4KM3A 3IG4A 2GGCA 4S01A 2Q8KA 1KP0A 4IDYA 5CDVA 2P98A 1CHMA 4ZWUA 4FUKA 1WL9A 4U6EA 2GA2A 1YJ3A 4U6JA 2GGBA 4ZWPA 2MATA 2V3XA 2GG5A 3MR1A 4FLIA 2GU4A 3L7GA 2GG2A 4IPAA 1WN1A 2B3LA 2BB7A 2BWXA 1XGSA 4FKCA 4FO8A 4QR8A 4U6WA 1W2MA 3CB6A 1KQ9A 2GG9A 3MATA 4FLLA 4A6WA 5CIKA 5D6FA 1KQ0A 2Q93A 4U6ZA 4FLKA 4U1BA 2G6PA 2Q95A 4RZZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1B6A A;  1XGO A;  3PKC A;  1XGN A;  2GG7 A;  2BHB A;  3RVA A;  1M35 A;  2BHA A;  4U75 A;  2OAZ A;  1WY2 A;  1YW8 A;  2GTX A;  5CLS A;  1W7V A;  3ROR A;  5CE6 A;  4U71 A;  1R5H A;  1R58 A;  2P9A A;  1QZY A;  5FCF A;  1C22 A;  1C27 A;  4ZWO A;  3S6B A;  1QXW A;  5CDE A;  2ADU A;  2BWS A;  4U6C A;  2BN7 A;  4IKT A;  4U70 A;  2Q94 A;  2EVC A;  1YW7 A;  4A6V A;  2BWT A;  5JHU A;  3BIP A;  2Q92 A;  4B28 A;  1C21 A;  4IKR A;  1JAW A;  2GU5 A;  2GG8 A;  2P99 A;  1WL6 A;  4S00 A;  1WLR A;  5CDL A;  3TAV A;  3MX6 A;  1B59 A;  2V3Y A;  2NQ6 A;  4PV4 A;  4RZY A;  5D6E A;  1A16 A;  3IU9 A;  4JUQ A;  2BWW A;  1BOA A;  2EA4 A;  2OKN A;  4EGE A;  5CNX A;  1YVM A;  4S2T P;  1MAT A;  1QXZ A;  4OOK A;  2BWU A;  1QXY A;  2HOW A;  3PKB A;  1BN5 A;  4Z7M A;  5JI6 A;  4U73 A;  3IU8 A;  4S2R P;  5E5B A;  2BH3 A;  1C24 A;  3FMR A;  4IKU A;  1C23 A;  3FM3 A;  3PKE A;  4IEC A;  1XGM A;  2IW2 A;  2BWV A;  4FO7 A;  2GG0 A;  2DFI A;  3BIT A;  1PV9 A;  2NQ7 A;  2BWY A;  4U69 A;  2V3Z A;  2EVO A;  3FMQ A;  5JFR A;  1XNZ A;  4IKS A;  3CTZ A;  4MAT A;  2B3H A;  4R60 A;  1WBQ A;  5FCH A;  4FLJ A;  4IU6 A;  4RGZ 1;  1N51 A;  4ZNG A;  3L24 A;  2EA2 A;  4PNC A;  1YW9 A;  1Y1N A;  4U76 A;  2GU7 A;  2GG3 A;  3Q6D A;  1O0X A;  3CB5 A;  4HXX A;  2BHD A;  1WKM A;  2Q96 A;  1R5G A;  3BIQ A;  2B3K A;  2BHC A;  3TB5 A;  2ZSG A;  4IF7 A;  2GZ5 A;  3PKA A;  2EVM A;  3IU7 A;  2GU6 A;  3PKD A;  3D27 A;  2V6C A;  4KM3 A;  3IG4 A;  2GGC A;  4S01 A;  2Q8K A;  1KP0 A;  4IDY A;  5CDV A;  2P98 A;  1CHM A;  4ZWU A;  4FUK A;  1WL9 A;  4U6E A;  2GA2 A;  1YJ3 A;  4U6J A;  2GGB A;  4ZWP A;  2MAT A;  2V3X A;  2GG5 A;  3MR1 A;  4FLI A;  2GU4 A;  3L7G A;  2GG2 A;  4IPA A;  1WN1 A;  2B3L A;  2BB7 A;  2BWX A;  1XGS A;  4FKC A;  4FO8 A;  4QR8 A;  4U6W A;  1W2M A;  3CB6 A;  1KQ9 A;  2GG9 A;  3MAT A;  4FLL A;  4A6W A;  5CIK A;  5D6F A;  1KQ0 A;  2Q93 A;  4U6Z A;  4FLK A;  4U1B A;  2G6P A;  2Q95 A;  4RZZ A; 
#chains in the Genus database with same CATH topology
 1B6A A;  1XGO A;  3PKC A;  1XGN A;  2GG7 A;  2BHB A;  3RVA A;  1M35 A;  2BHA A;  4U75 A;  2OAZ A;  1WY2 A;  1YW8 A;  2GTX A;  5CLS A;  1W7V A;  3ROR A;  5CE6 A;  4U71 A;  1R5H A;  1R58 A;  2P9A A;  1QZY A;  5FCF A;  1C22 A;  1C27 A;  4ZWO A;  3S6B A;  1QXW A;  5CDE A;  2ADU A;  2BWS A;  4U6C A;  2BN7 A;  4IKT A;  4U70 A;  2Q94 A;  2EVC A;  1YW7 A;  4A6V A;  2BWT A;  5JHU A;  3BIP A;  2Q92 A;  4B28 A;  1C21 A;  4IKR A;  1JAW A;  2GU5 A;  2GG8 A;  2P99 A;  1WL6 A;  4S00 A;  1WLR A;  5CDL A;  3TAV A;  3MX6 A;  1B59 A;  2V3Y A;  2NQ6 A;  4PV4 A;  4RZY A;  5D6E A;  1A16 A;  3IU9 A;  4JUQ A;  2BWW A;  1BOA A;  2EA4 A;  2OKN A;  4EGE A;  5CNX A;  1YVM A;  4S2T P;  1MAT A;  1QXZ A;  4OOK A;  2BWU A;  1QXY A;  2HOW A;  3PKB A;  1BN5 A;  4Z7M A;  5JI6 A;  4U73 A;  3IU8 A;  4S2R P;  5E5B A;  2BH3 A;  1C24 A;  3FMR A;  4IKU A;  1C23 A;  3FM3 A;  3PKE A;  4IEC A;  1XGM A;  2IW2 A;  2BWV A;  4FO7 A;  2GG0 A;  2DFI A;  3BIT A;  1PV9 A;  2NQ7 A;  2BWY A;  4U69 A;  2V3Z A;  2EVO A;  3FMQ A;  5JFR A;  1XNZ A;  4IKS A;  3CTZ A;  4MAT A;  2B3H A;  4R60 A;  1WBQ A;  5FCH A;  4FLJ A;  4IU6 A;  4RGZ 1;  1N51 A;  4ZNG A;  3L24 A;  2EA2 A;  4PNC A;  1YW9 A;  1Y1N A;  4U76 A;  2GU7 A;  2GG3 A;  3Q6D A;  1O0X A;  3CB5 A;  4HXX A;  2BHD A;  1WKM A;  2Q96 A;  1R5G A;  3BIQ A;  2B3K A;  2BHC A;  3TB5 A;  2ZSG A;  4IF7 A;  2GZ5 A;  3PKA A;  2EVM A;  3IU7 A;  2GU6 A;  3PKD A;  3D27 A;  2V6C A;  4KM3 A;  3IG4 A;  2GGC A;  4S01 A;  2Q8K A;  1KP0 A;  4IDY A;  5CDV A;  2P98 A;  1CHM A;  4ZWU A;  4FUK A;  1WL9 A;  4U6E A;  2GA2 A;  1YJ3 A;  4U6J A;  2GGB A;  4ZWP A;  2MAT A;  2V3X A;  2GG5 A;  3MR1 A;  4FLI A;  2GU4 A;  3L7G A;  2GG2 A;  4IPA A;  1WN1 A;  2B3L A;  2BB7 A;  2BWX A;  1XGS A;  4FKC A;  4FO8 A;  4QR8 A;  4U6W A;  1W2M A;  3CB6 A;  1KQ9 A;  2GG9 A;  3MAT A;  4FLL A;  4A6W A;  5CIK A;  5D6F A;  1KQ0 A;  2Q93 A;  4U6Z A;  4FLK A;  4U1B A;  2G6P A;  2Q95 A;  4RZZ A; 
#chains in the Genus database with same CATH homology
 1B6A A;  1XGO A;  3PKC A;  1XGN A;  2GG7 A;  2BHB A;  3RVA A;  1M35 A;  2BHA A;  4U75 A;  2OAZ A;  1WY2 A;  1YW8 A;  2GTX A;  5CLS A;  1W7V A;  3ROR A;  5CE6 A;  4U71 A;  1R5H A;  1R58 A;  2P9A A;  1QZY A;  5FCF A;  1C22 A;  1C27 A;  4ZWO A;  3S6B A;  1QXW A;  5CDE A;  2ADU A;  2BWS A;  4U6C A;  2BN7 A;  4IKT A;  4U70 A;  2Q94 A;  2EVC A;  1YW7 A;  4A6V A;  2BWT A;  5JHU A;  3BIP A;  2Q92 A;  4B28 A;  1C21 A;  4IKR A;  1JAW A;  2GU5 A;  2GG8 A;  2P99 A;  1WL6 A;  4S00 A;  1WLR A;  5CDL A;  3TAV A;  3MX6 A;  1B59 A;  2V3Y A;  2NQ6 A;  4PV4 A;  4RZY A;  5D6E A;  1A16 A;  3IU9 A;  4JUQ A;  2BWW A;  1BOA A;  2EA4 A;  2OKN A;  4EGE A;  5CNX A;  1YVM A;  4S2T P;  1MAT A;  1QXZ A;  4OOK A;  2BWU A;  1QXY A;  2HOW A;  3PKB A;  1BN5 A;  4Z7M A;  5JI6 A;  4U73 A;  3IU8 A;  4S2R P;  5E5B A;  2BH3 A;  1C24 A;  3FMR A;  4IKU A;  1C23 A;  3FM3 A;  3PKE A;  4IEC A;  1XGM A;  2IW2 A;  2BWV A;  4FO7 A;  2GG0 A;  2DFI A;  3BIT A;  1PV9 A;  2NQ7 A;  2BWY A;  4U69 A;  2V3Z A;  2EVO A;  3FMQ A;  5JFR A;  1XNZ A;  4IKS A;  3CTZ A;  4MAT A;  2B3H A;  4R60 A;  1WBQ A;  5FCH A;  4FLJ A;  4IU6 A;  4RGZ 1;  1N51 A;  4ZNG A;  3L24 A;  2EA2 A;  4PNC A;  1YW9 A;  1Y1N A;  4U76 A;  2GU7 A;  2GG3 A;  3Q6D A;  1O0X A;  3CB5 A;  4HXX A;  2BHD A;  1WKM A;  2Q96 A;  1R5G A;  3BIQ A;  2B3K A;  2BHC A;  3TB5 A;  2ZSG A;  4IF7 A;  2GZ5 A;  3PKA A;  2EVM A;  3IU7 A;  2GU6 A;  3PKD A;  3D27 A;  2V6C A;  4KM3 A;  3IG4 A;  2GGC A;  4S01 A;  2Q8K A;  1KP0 A;  4IDY A;  5CDV A;  2P98 A;  1CHM A;  4ZWU A;  4FUK A;  1WL9 A;  4U6E A;  2GA2 A;  1YJ3 A;  4U6J A;  2GGB A;  4ZWP A;  2MAT A;  2V3X A;  2GG5 A;  3MR1 A;  4FLI A;  2GU4 A;  3L7G A;  2GG2 A;  4IPA A;  1WN1 A;  2B3L A;  2BB7 A;  2BWX A;  1XGS A;  4FKC A;  4FO8 A;  4QR8 A;  4U6W A;  1W2M A;  3CB6 A;  1KQ9 A;  2GG9 A;  3MAT A;  4FLL A;  4A6W A;  5CIK A;  5D6F A;  1KQ0 A;  2Q93 A;  4U6Z A;  4FLK A;  4U1B A;  2G6P A;  2Q95 A;  4RZZ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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