3PKCA

M. tuberculosis metap with bengamide analog y08, in mn form
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
281
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTC'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
total genus 86
structure length 281
sequence length 281
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkcA01
1QXZA 4FLKA 1XGNA 4RGZ1 4IKRA 3L24A 4U76A 1WN1A 1XGMA 2IW2A 4OOKA 1C23A 1R5GA 4U6ZA 5CNXA 3Q6DA 3TAVA 2GGCA 2Q95A 1BN5A 2Q92A 5JI6A 4B28A 1C24A 2BN7A 4FLIA 4IKUA 4IKSA 2GZ5A 3BITA 4U73A 4PNCA 5D6FA 5CLSA 3CB6A 4IECA 1R5HA 2BH3A 4RZZA 2NQ6A 3RORA 4JUQA 3CB5A 2GU7A 2NQ7A 1Y1NA 2DFIA 4U75A 5FCFA 2OKNA 1C27A 4FLLA 3FM3A 1O0XA 2GG9A 2EVCA 2ADUA 1WBQA 3PKBA 4A6WA 3PKAA 1KP0A 4U1BA 2EA4A 2GU4A 3L7GA 1MATA 1PV9A 2BWSA 2GTXA 2BWYA 1YW9A 2BWVA 2EA2A 2GG8A 4QR8A 1QZYA 4PV4A 2GU5A 3CTZA 4S01A 4FO8A 4FUKA 4ZNGA 1YW7A 1YW8A 1YJ3A 2Q8KA 1XGSA 2Q94A 4MATA 5D6EA 2GG2A 3IU7A 1M35A 2P99A 4IF7A 5JHUA 4U6EA 4U71A 3IU9A 2P9AA 3BIQA 3PKEA 3RVAA 4FO7A 3FMQA 4ZWUA 2MATA 4R60A 2BB7A 4S00A 4FLJA 5FCHA 1N51A 5CDVA 2ZSGA 2B3KA 5CDEA 4IU6A 4RZYA 1WKMA 2GG5A 4U6JA 5CE6A 2G6PA 2BWTA 3D27A 5E5BA 2BHBA 3BIPA 4ZWPA 3TB5A 1QXYA 4U6WA 2EVMA 2Q93A 4A6VA 4EGEA 2GGBA 1B6AA 1KQ9A 2BHDA 1C21A 2OAZA 1CHMA 4IPAA 1BOAA 1R58A 2BWWA 1WY2A 1XNZA 1YVMA 4FKCA 3MATA 2GG3A 1XGOA 3IG4A 2BHCA 2HOWA 1WL9A 2GU6A 2GA2A 5CIKA 1B59A 3S6BA 2P98A 3FMRA 4ZWOA 4U6CA 2GG0A 2V6CA 4IKTA 2V3ZA 4U70A 1C22A 2V3YA 1A16A 4KM3A 5JFRA 2BHAA 4Z7MA 1W7VA 4S2TP 2BWUA 4S2RP 3PKDA 2BWXA 2V3XA 4IDYA 2EVOA 1WLRA 1WL6A 2B3LA 3PKCA 3IU8A 1QXWA 4HXXA 2Q96A 2GG7A 5CDLA 3MR1A 1W2MA 1KQ0A 1JAWA 2B3HA 3MX6A 4U69A
chains in the Genus database with same CATH superfamily
1QXZA 4FLKA 1XGNA 4RGZ1 4IKRA 3L24A 4U76A 1WN1A 1XGMA 2IW2A 4OOKA 1C23A 1R5GA 4U6ZA 5CNXA 3Q6DA 3TAVA 2GGCA 2Q95A 1BN5A 2Q92A 5JI6A 4B28A 1C24A 2BN7A 4FLIA 4IKUA 4IKSA 2GZ5A 3BITA 4U73A 4PNCA 5D6FA 5CLSA 3CB6A 4IECA 1R5HA 2BH3A 4RZZA 2NQ6A 3RORA 4JUQA 3CB5A 2GU7A 2NQ7A 1Y1NA 2DFIA 4U75A 5FCFA 2OKNA 1C27A 4FLLA 3FM3A 1O0XA 2GG9A 2EVCA 2ADUA 1WBQA 3PKBA 4A6WA 3PKAA 1KP0A 4U1BA 2EA4A 2GU4A 3L7GA 1MATA 1PV9A 2BWSA 2GTXA 2BWYA 1YW9A 2BWVA 2EA2A 2GG8A 4QR8A 1QZYA 4PV4A 2GU5A 3CTZA 4S01A 4FO8A 4FUKA 4ZNGA 1YW7A 1YW8A 1YJ3A 2Q8KA 1XGSA 2Q94A 4MATA 5D6EA 2GG2A 3IU7A 1M35A 2P99A 4IF7A 5JHUA 4U6EA 4U71A 3IU9A 2P9AA 3BIQA 3PKEA 3RVAA 4FO7A 3FMQA 4ZWUA 2MATA 4R60A 2BB7A 4S00A 4FLJA 5FCHA 1N51A 5CDVA 2ZSGA 2B3KA 5CDEA 4IU6A 4RZYA 1WKMA 2GG5A 4U6JA 5CE6A 2G6PA 2BWTA 3D27A 5E5BA 2BHBA 3BIPA 4ZWPA 3TB5A 1QXYA 4U6WA 2EVMA 2Q93A 4A6VA 4EGEA 2GGBA 1B6AA 1KQ9A 2BHDA 1C21A 2OAZA 1CHMA 4IPAA 1BOAA 1R58A 2BWWA 1WY2A 1XNZA 1YVMA 4FKCA 3MATA 2GG3A 1XGOA 3IG4A 2BHCA 2HOWA 1WL9A 2GU6A 2GA2A 5CIKA 1B59A 3S6BA 2P98A 3FMRA 4ZWOA 4U6CA 2GG0A 2V6CA 4IKTA 2V3ZA 4U70A 1C22A 2V3YA 1A16A 4KM3A 5JFRA 2BHAA 4Z7MA 1W7VA 4S2TP 2BWUA 4S2RP 3PKDA 2BWXA 2V3XA 4IDYA 2EVOA 1WLRA 1WL6A 2B3LA 3PKCA 3IU8A 1QXWA 4HXXA 2Q96A 2GG7A 5CDLA 3MR1A 1W2MA 1KQ0A 1JAWA 2B3HA 3MX6A 4U69A
chains in the Genus database with same CATH topology
1QXZA 4FLKA 1XGNA 4RGZ1 4IKRA 3L24A 4U76A 1WN1A 1XGMA 2IW2A 4OOKA 1C23A 1R5GA 4U6ZA 5CNXA 3Q6DA 3TAVA 2GGCA 2Q95A 1BN5A 2Q92A 5JI6A 4B28A 1C24A 2BN7A 4FLIA 4IKUA 4IKSA 2GZ5A 3BITA 4U73A 4PNCA 5D6FA 5CLSA 3CB6A 4IECA 1R5HA 2BH3A 4RZZA 2NQ6A 3RORA 4JUQA 3CB5A 2GU7A 2NQ7A 1Y1NA 2DFIA 4U75A 5FCFA 2OKNA 1C27A 4FLLA 3FM3A 1O0XA 2GG9A 2EVCA 2ADUA 1WBQA 3PKBA 4A6WA 3PKAA 1KP0A 4U1BA 2EA4A 2GU4A 3L7GA 1MATA 1PV9A 2BWSA 2GTXA 2BWYA 1YW9A 2BWVA 2EA2A 2GG8A 4QR8A 1QZYA 4PV4A 2GU5A 3CTZA 4S01A 4FO8A 4FUKA 4ZNGA 1YW7A 1YW8A 1YJ3A 2Q8KA 1XGSA 2Q94A 4MATA 5D6EA 2GG2A 3IU7A 1M35A 2P99A 4IF7A 5JHUA 4U6EA 4U71A 3IU9A 2P9AA 3BIQA 3PKEA 3RVAA 4FO7A 3FMQA 4ZWUA 2MATA 4R60A 2BB7A 4S00A 4FLJA 5FCHA 1N51A 5CDVA 2ZSGA 2B3KA 5CDEA 4IU6A 4RZYA 1WKMA 2GG5A 4U6JA 5CE6A 2G6PA 2BWTA 3D27A 5E5BA 2BHBA 3BIPA 4ZWPA 3TB5A 1QXYA 4U6WA 2EVMA 2Q93A 4A6VA 4EGEA 2GGBA 1B6AA 1KQ9A 2BHDA 1C21A 2OAZA 1CHMA 4IPAA 1BOAA 1R58A 2BWWA 1WY2A 1XNZA 1YVMA 4FKCA 3MATA 2GG3A 1XGOA 3IG4A 2BHCA 2HOWA 1WL9A 2GU6A 2GA2A 5CIKA 1B59A 3S6BA 2P98A 3FMRA 4ZWOA 4U6CA 2GG0A 2V6CA 4IKTA 2V3ZA 4U70A 1C22A 2V3YA 1A16A 4KM3A 5JFRA 2BHAA 4Z7MA 1W7VA 4S2TP 2BWUA 4S2RP 3PKDA 2BWXA 2V3XA 4IDYA 2EVOA 1WLRA 1WL6A 2B3LA 3PKCA 3IU8A 1QXWA 4HXXA 2Q96A 2GG7A 5CDLA 3MR1A 1W2MA 1KQ0A 1JAWA 2B3HA 3MX6A 4U69A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QXZ A;  4FLK A;  1XGN A;  4RGZ 1;  4IKR A;  3L24 A;  4U76 A;  1WN1 A;  1XGM A;  2IW2 A;  4OOK A;  1C23 A;  1R5G A;  4U6Z A;  5CNX A;  3Q6D A;  3TAV A;  2GGC A;  2Q95 A;  1BN5 A;  2Q92 A;  5JI6 A;  4B28 A;  1C24 A;  2BN7 A;  4FLI A;  4IKU A;  4IKS A;  2GZ5 A;  3BIT A;  4U73 A;  4PNC A;  5D6F A;  5CLS A;  3CB6 A;  4IEC A;  1R5H A;  2BH3 A;  4RZZ A;  2NQ6 A;  3ROR A;  4JUQ A;  3CB5 A;  2GU7 A;  2NQ7 A;  1Y1N A;  2DFI A;  4U75 A;  5FCF A;  2OKN A;  1C27 A;  4FLL A;  3FM3 A;  1O0X A;  2GG9 A;  2EVC A;  2ADU A;  1WBQ A;  3PKB A;  4A6W A;  3PKA A;  1KP0 A;  4U1B A;  2EA4 A;  2GU4 A;  3L7G A;  1MAT A;  1PV9 A;  2BWS A;  2GTX A;  2BWY A;  1YW9 A;  2BWV A;  2EA2 A;  2GG8 A;  4QR8 A;  1QZY A;  4PV4 A;  2GU5 A;  3CTZ A;  4S01 A;  4FO8 A;  4FUK A;  4ZNG A;  1YW7 A;  1YW8 A;  1YJ3 A;  2Q8K A;  1XGS A;  2Q94 A;  4MAT A;  5D6E A;  2GG2 A;  3IU7 A;  1M35 A;  2P99 A;  4IF7 A;  5JHU A;  4U6E A;  4U71 A;  3IU9 A;  2P9A A;  3BIQ A;  3PKE A;  3RVA A;  4FO7 A;  3FMQ A;  4ZWU A;  2MAT A;  4R60 A;  2BB7 A;  4S00 A;  4FLJ A;  5FCH A;  1N51 A;  5CDV A;  2ZSG A;  2B3K A;  5CDE A;  4IU6 A;  4RZY A;  1WKM A;  2GG5 A;  4U6J A;  5CE6 A;  2G6P A;  2BWT A;  3D27 A;  5E5B A;  2BHB A;  3BIP A;  4ZWP A;  3TB5 A;  1QXY A;  4U6W A;  2EVM A;  2Q93 A;  4A6V A;  4EGE A;  2GGB A;  1B6A A;  1KQ9 A;  2BHD A;  1C21 A;  2OAZ A;  1CHM A;  4IPA A;  1BOA A;  1R58 A;  2BWW A;  1WY2 A;  1XNZ A;  1YVM A;  4FKC A;  3MAT A;  2GG3 A;  1XGO A;  3IG4 A;  2BHC A;  2HOW A;  1WL9 A;  2GU6 A;  2GA2 A;  5CIK A;  1B59 A;  3S6B A;  2P98 A;  3FMR A;  4ZWO A;  4U6C A;  2GG0 A;  2V6C A;  4IKT A;  2V3Z A;  4U70 A;  1C22 A;  2V3Y A;  1A16 A;  4KM3 A;  5JFR A;  2BHA A;  4Z7M A;  1W7V A;  4S2T P;  2BWU A;  4S2R P;  3PKD A;  2BWX A;  2V3X A;  4IDY A;  2EVO A;  1WLR A;  1WL6 A;  2B3L A;  3PKC A;  3IU8 A;  1QXW A;  4HXX A;  2Q96 A;  2GG7 A;  5CDL A;  3MR1 A;  1W2M A;  1KQ0 A;  1JAW A;  2B3H A;  3MX6 A;  4U69 A; 
#chains in the Genus database with same CATH topology
 1QXZ A;  4FLK A;  1XGN A;  4RGZ 1;  4IKR A;  3L24 A;  4U76 A;  1WN1 A;  1XGM A;  2IW2 A;  4OOK A;  1C23 A;  1R5G A;  4U6Z A;  5CNX A;  3Q6D A;  3TAV A;  2GGC A;  2Q95 A;  1BN5 A;  2Q92 A;  5JI6 A;  4B28 A;  1C24 A;  2BN7 A;  4FLI A;  4IKU A;  4IKS A;  2GZ5 A;  3BIT A;  4U73 A;  4PNC A;  5D6F A;  5CLS A;  3CB6 A;  4IEC A;  1R5H A;  2BH3 A;  4RZZ A;  2NQ6 A;  3ROR A;  4JUQ A;  3CB5 A;  2GU7 A;  2NQ7 A;  1Y1N A;  2DFI A;  4U75 A;  5FCF A;  2OKN A;  1C27 A;  4FLL A;  3FM3 A;  1O0X A;  2GG9 A;  2EVC A;  2ADU A;  1WBQ A;  3PKB A;  4A6W A;  3PKA A;  1KP0 A;  4U1B A;  2EA4 A;  2GU4 A;  3L7G A;  1MAT A;  1PV9 A;  2BWS A;  2GTX A;  2BWY A;  1YW9 A;  2BWV A;  2EA2 A;  2GG8 A;  4QR8 A;  1QZY A;  4PV4 A;  2GU5 A;  3CTZ A;  4S01 A;  4FO8 A;  4FUK A;  4ZNG A;  1YW7 A;  1YW8 A;  1YJ3 A;  2Q8K A;  1XGS A;  2Q94 A;  4MAT A;  5D6E A;  2GG2 A;  3IU7 A;  1M35 A;  2P99 A;  4IF7 A;  5JHU A;  4U6E A;  4U71 A;  3IU9 A;  2P9A A;  3BIQ A;  3PKE A;  3RVA A;  4FO7 A;  3FMQ A;  4ZWU A;  2MAT A;  4R60 A;  2BB7 A;  4S00 A;  4FLJ A;  5FCH A;  1N51 A;  5CDV A;  2ZSG A;  2B3K A;  5CDE A;  4IU6 A;  4RZY A;  1WKM A;  2GG5 A;  4U6J A;  5CE6 A;  2G6P A;  2BWT A;  3D27 A;  5E5B A;  2BHB A;  3BIP A;  4ZWP A;  3TB5 A;  1QXY A;  4U6W A;  2EVM A;  2Q93 A;  4A6V A;  4EGE A;  2GGB A;  1B6A A;  1KQ9 A;  2BHD A;  1C21 A;  2OAZ A;  1CHM A;  4IPA A;  1BOA A;  1R58 A;  2BWW A;  1WY2 A;  1XNZ A;  1YVM A;  4FKC A;  3MAT A;  2GG3 A;  1XGO A;  3IG4 A;  2BHC A;  2HOW A;  1WL9 A;  2GU6 A;  2GA2 A;  5CIK A;  1B59 A;  3S6B A;  2P98 A;  3FMR A;  4ZWO A;  4U6C A;  2GG0 A;  2V6C A;  4IKT A;  2V3Z A;  4U70 A;  1C22 A;  2V3Y A;  1A16 A;  4KM3 A;  5JFR A;  2BHA A;  4Z7M A;  1W7V A;  4S2T P;  2BWU A;  4S2R P;  3PKD A;  2BWX A;  2V3X A;  4IDY A;  2EVO A;  1WLR A;  1WL6 A;  2B3L A;  3PKC A;  3IU8 A;  1QXW A;  4HXX A;  2Q96 A;  2GG7 A;  5CDL A;  3MR1 A;  1W2M A;  1KQ0 A;  1JAW A;  2B3H A;  3MX6 A;  4U69 A; 
#chains in the Genus database with same CATH homology
 1QXZ A;  4FLK A;  1XGN A;  4RGZ 1;  4IKR A;  3L24 A;  4U76 A;  1WN1 A;  1XGM A;  2IW2 A;  4OOK A;  1C23 A;  1R5G A;  4U6Z A;  5CNX A;  3Q6D A;  3TAV A;  2GGC A;  2Q95 A;  1BN5 A;  2Q92 A;  5JI6 A;  4B28 A;  1C24 A;  2BN7 A;  4FLI A;  4IKU A;  4IKS A;  2GZ5 A;  3BIT A;  4U73 A;  4PNC A;  5D6F A;  5CLS A;  3CB6 A;  4IEC A;  1R5H A;  2BH3 A;  4RZZ A;  2NQ6 A;  3ROR A;  4JUQ A;  3CB5 A;  2GU7 A;  2NQ7 A;  1Y1N A;  2DFI A;  4U75 A;  5FCF A;  2OKN A;  1C27 A;  4FLL A;  3FM3 A;  1O0X A;  2GG9 A;  2EVC A;  2ADU A;  1WBQ A;  3PKB A;  4A6W A;  3PKA A;  1KP0 A;  4U1B A;  2EA4 A;  2GU4 A;  3L7G A;  1MAT A;  1PV9 A;  2BWS A;  2GTX A;  2BWY A;  1YW9 A;  2BWV A;  2EA2 A;  2GG8 A;  4QR8 A;  1QZY A;  4PV4 A;  2GU5 A;  3CTZ A;  4S01 A;  4FO8 A;  4FUK A;  4ZNG A;  1YW7 A;  1YW8 A;  1YJ3 A;  2Q8K A;  1XGS A;  2Q94 A;  4MAT A;  5D6E A;  2GG2 A;  3IU7 A;  1M35 A;  2P99 A;  4IF7 A;  5JHU A;  4U6E A;  4U71 A;  3IU9 A;  2P9A A;  3BIQ A;  3PKE A;  3RVA A;  4FO7 A;  3FMQ A;  4ZWU A;  2MAT A;  4R60 A;  2BB7 A;  4S00 A;  4FLJ A;  5FCH A;  1N51 A;  5CDV A;  2ZSG A;  2B3K A;  5CDE A;  4IU6 A;  4RZY A;  1WKM A;  2GG5 A;  4U6J A;  5CE6 A;  2G6P A;  2BWT A;  3D27 A;  5E5B A;  2BHB A;  3BIP A;  4ZWP A;  3TB5 A;  1QXY A;  4U6W A;  2EVM A;  2Q93 A;  4A6V A;  4EGE A;  2GGB A;  1B6A A;  1KQ9 A;  2BHD A;  1C21 A;  2OAZ A;  1CHM A;  4IPA A;  1BOA A;  1R58 A;  2BWW A;  1WY2 A;  1XNZ A;  1YVM A;  4FKC A;  3MAT A;  2GG3 A;  1XGO A;  3IG4 A;  2BHC A;  2HOW A;  1WL9 A;  2GU6 A;  2GA2 A;  5CIK A;  1B59 A;  3S6B A;  2P98 A;  3FMR A;  4ZWO A;  4U6C A;  2GG0 A;  2V6C A;  4IKT A;  2V3Z A;  4U70 A;  1C22 A;  2V3Y A;  1A16 A;  4KM3 A;  5JFR A;  2BHA A;  4Z7M A;  1W7V A;  4S2T P;  2BWU A;  4S2R P;  3PKD A;  2BWX A;  2V3X A;  4IDY A;  2EVO A;  1WLR A;  1WL6 A;  2B3L A;  3PKC A;  3IU8 A;  1QXW A;  4HXX A;  2Q96 A;  2GG7 A;  5CDL A;  3MR1 A;  1W2M A;  1KQ0 A;  1JAW A;  2B3H A;  3MX6 A;  4U69 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...