3PKCA

M. tuberculosis metap with bengamide analog y08, in mn form
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
281
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTC
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 86
structure length 281
sequence length 281
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkcA01
2BHDA 3D27A 1XGSA 2BB7A 2NQ6A 3L7GA 1N51A 2EA2A 2BHCA 2BWYA 5D6FA 1KQ9A 2GGBA 4A6WA 2GG5A 3BIPA 4JUQA 2Q93A 4U75A 2G6PA 2OKNA 4ZWUA 2BH3A 2EVMA 2GTXA 1C27A 3PKDA 4IKUA 4FO8A 1B6AA 1O0XA 4ZWPA 4RZZA 1W7VA 4HXXA 1XGMA 3Q6DA 3IU9A 4EGEA 2GG8A 4Z7MA 2GU6A 2ZSGA 2B3KA 1WY2A 3CB6A 2Q8KA 3PKBA 3MATA 1MATA 3PKEA 1KQ0A 1WL9A 2V3XA 4U1BA 1A16A 2V6CA 4U71A 1KP0A 2GGCA 1XNZA 1QXWA 1R5HA 2ADUA 4IKTA 4U73A 5CDEA 2NQ7A 4ZNGA 1WN1A 1Y1NA 1CHMA 1B59A 2GG0A 2GG7A 2BN7A 1YW7A 1C22A 5CDLA 1QZYA 1YJ3A 4IKSA 3IG4A 2EA4A 5CLSA 4IECA 2P9AA 2EVCA 5CNXA 2Q95A 4FUKA 5CE6A 3MR1A 1C23A 1XGOA 2V3YA 4IF7A 3PKAA 5JI6A 2MATA 3MX6A 3PKCA 4RZYA 4U6JA 1BN5A 3FMQA 4FLJA 2GA2A 1WBQA 3CTZA 4IU6A 4QR8A 5CIKA 2BHAA 3CB5A 4FLKA 1R58A 2Q96A 4RGZ1 4S00A 2IW2A 1W2MA 1XGNA 4U70A 2GG3A 1QXZA 5E5BA 2OAZA 3L24A 1M35A 4PV4A 4U76A 4ZWOA 2HOWA 2BHBA 3S6BA 2BWVA 1WL6A 2Q92A 2P99A 2GG2A 4MATA 5CDVA 3BIQA 2BWSA 4PNCA 4FO7A 3FMRA 2GU5A 4U69A 4U6CA 4U6WA 2BWXA 5JFRA 4A6VA 4U6ZA 2GG9A 3IU7A 5FCHA 2V3ZA 1YW8A 3FM3A 2GU7A 5JHUA 1R5GA 4OOKA 1WLRA 1QXYA 1YVMA 3RORA 1WKMA 3BITA 4S2TP 2B3LA 4FKCA 2BWUA 2DFIA 4R60A 5D6EA 4FLIA 4S2RP 3TAVA 1YW9A 3TB5A 4IDYA 3IU8A 4IPAA 1C24A 1C21A 2Q94A 4KM3A 2P98A 5FCFA 2GZ5A 4IKRA 2B3HA 2BWTA 1BOAA 4FLLA 1PV9A 2GU4A 3RVAA 4S01A 1JAWA 2BWWA 4U6EA 2EVOA 4B28A
chains in the Genus database with same CATH superfamily
2BHDA 3D27A 1XGSA 2BB7A 2NQ6A 3L7GA 1N51A 2EA2A 2BHCA 2BWYA 5D6FA 1KQ9A 2GGBA 4A6WA 2GG5A 3BIPA 4JUQA 2Q93A 4U75A 2G6PA 2OKNA 4ZWUA 2BH3A 2EVMA 2GTXA 1C27A 3PKDA 4IKUA 4FO8A 1B6AA 1O0XA 4ZWPA 4RZZA 1W7VA 4HXXA 1XGMA 3Q6DA 3IU9A 4EGEA 2GG8A 4Z7MA 2GU6A 2ZSGA 2B3KA 1WY2A 3CB6A 2Q8KA 3PKBA 3MATA 1MATA 3PKEA 1KQ0A 1WL9A 2V3XA 4U1BA 1A16A 2V6CA 4U71A 1KP0A 2GGCA 1XNZA 1QXWA 1R5HA 2ADUA 4IKTA 4U73A 5CDEA 2NQ7A 4ZNGA 1WN1A 1Y1NA 1CHMA 1B59A 2GG0A 2GG7A 2BN7A 1YW7A 1C22A 5CDLA 1QZYA 1YJ3A 4IKSA 3IG4A 2EA4A 5CLSA 4IECA 2P9AA 2EVCA 5CNXA 2Q95A 4FUKA 5CE6A 3MR1A 1C23A 1XGOA 2V3YA 4IF7A 3PKAA 5JI6A 2MATA 3MX6A 3PKCA 4RZYA 4U6JA 1BN5A 3FMQA 4FLJA 2GA2A 1WBQA 3CTZA 4IU6A 4QR8A 5CIKA 2BHAA 3CB5A 4FLKA 1R58A 2Q96A 4RGZ1 4S00A 2IW2A 1W2MA 1XGNA 4U70A 2GG3A 1QXZA 5E5BA 2OAZA 3L24A 1M35A 4PV4A 4U76A 4ZWOA 2HOWA 2BHBA 3S6BA 2BWVA 1WL6A 2Q92A 2P99A 2GG2A 4MATA 5CDVA 3BIQA 2BWSA 4PNCA 4FO7A 3FMRA 2GU5A 4U69A 4U6CA 4U6WA 2BWXA 5JFRA 4A6VA 4U6ZA 2GG9A 3IU7A 5FCHA 2V3ZA 1YW8A 3FM3A 2GU7A 5JHUA 1R5GA 4OOKA 1WLRA 1QXYA 1YVMA 3RORA 1WKMA 3BITA 4S2TP 2B3LA 4FKCA 2BWUA 2DFIA 4R60A 5D6EA 4FLIA 4S2RP 3TAVA 1YW9A 3TB5A 4IDYA 3IU8A 4IPAA 1C24A 1C21A 2Q94A 4KM3A 2P98A 5FCFA 2GZ5A 4IKRA 2B3HA 2BWTA 1BOAA 4FLLA 1PV9A 2GU4A 3RVAA 4S01A 1JAWA 2BWWA 4U6EA 2EVOA 4B28A
chains in the Genus database with same CATH topology
2BHDA 3D27A 1XGSA 2BB7A 2NQ6A 3L7GA 1N51A 2EA2A 2BHCA 2BWYA 5D6FA 1KQ9A 2GGBA 4A6WA 2GG5A 3BIPA 4JUQA 2Q93A 4U75A 2G6PA 2OKNA 4ZWUA 2BH3A 2EVMA 2GTXA 1C27A 3PKDA 4IKUA 4FO8A 1B6AA 1O0XA 4ZWPA 4RZZA 1W7VA 4HXXA 1XGMA 3Q6DA 3IU9A 4EGEA 2GG8A 4Z7MA 2GU6A 2ZSGA 2B3KA 1WY2A 3CB6A 2Q8KA 3PKBA 3MATA 1MATA 3PKEA 1KQ0A 1WL9A 2V3XA 4U1BA 1A16A 2V6CA 4U71A 1KP0A 2GGCA 1XNZA 1QXWA 1R5HA 2ADUA 4IKTA 4U73A 5CDEA 2NQ7A 4ZNGA 1WN1A 1Y1NA 1CHMA 1B59A 2GG0A 2GG7A 2BN7A 1YW7A 1C22A 5CDLA 1QZYA 1YJ3A 4IKSA 3IG4A 2EA4A 5CLSA 4IECA 2P9AA 2EVCA 5CNXA 2Q95A 4FUKA 5CE6A 3MR1A 1C23A 1XGOA 2V3YA 4IF7A 3PKAA 5JI6A 2MATA 3MX6A 3PKCA 4RZYA 4U6JA 1BN5A 3FMQA 4FLJA 2GA2A 1WBQA 3CTZA 4IU6A 4QR8A 5CIKA 2BHAA 3CB5A 4FLKA 1R58A 2Q96A 4RGZ1 4S00A 2IW2A 1W2MA 1XGNA 4U70A 2GG3A 1QXZA 5E5BA 2OAZA 3L24A 1M35A 4PV4A 4U76A 4ZWOA 2HOWA 2BHBA 3S6BA 2BWVA 1WL6A 2Q92A 2P99A 2GG2A 4MATA 5CDVA 3BIQA 2BWSA 4PNCA 4FO7A 3FMRA 2GU5A 4U69A 4U6CA 4U6WA 2BWXA 5JFRA 4A6VA 4U6ZA 2GG9A 3IU7A 5FCHA 2V3ZA 1YW8A 3FM3A 2GU7A 5JHUA 1R5GA 4OOKA 1WLRA 1QXYA 1YVMA 3RORA 1WKMA 3BITA 4S2TP 2B3LA 4FKCA 2BWUA 2DFIA 4R60A 5D6EA 4FLIA 4S2RP 3TAVA 1YW9A 3TB5A 4IDYA 3IU8A 4IPAA 1C24A 1C21A 2Q94A 4KM3A 2P98A 5FCFA 2GZ5A 4IKRA 2B3HA 2BWTA 1BOAA 4FLLA 1PV9A 2GU4A 3RVAA 4S01A 1JAWA 2BWWA 4U6EA 2EVOA 4B28A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BHD A;  3D27 A;  1XGS A;  2BB7 A;  2NQ6 A;  3L7G A;  1N51 A;  2EA2 A;  2BHC A;  2BWY A;  5D6F A;  1KQ9 A;  2GGB A;  4A6W A;  2GG5 A;  3BIP A;  4JUQ A;  2Q93 A;  4U75 A;  2G6P A;  2OKN A;  4ZWU A;  2BH3 A;  2EVM A;  2GTX A;  1C27 A;  3PKD A;  4IKU A;  4FO8 A;  1B6A A;  1O0X A;  4ZWP A;  4RZZ A;  1W7V A;  4HXX A;  1XGM A;  3Q6D A;  3IU9 A;  4EGE A;  2GG8 A;  4Z7M A;  2GU6 A;  2ZSG A;  2B3K A;  1WY2 A;  3CB6 A;  2Q8K A;  3PKB A;  3MAT A;  1MAT A;  3PKE A;  1KQ0 A;  1WL9 A;  2V3X A;  4U1B A;  1A16 A;  2V6C A;  4U71 A;  1KP0 A;  2GGC A;  1XNZ A;  1QXW A;  1R5H A;  2ADU A;  4IKT A;  4U73 A;  5CDE A;  2NQ7 A;  4ZNG A;  1WN1 A;  1Y1N A;  1CHM A;  1B59 A;  2GG0 A;  2GG7 A;  2BN7 A;  1YW7 A;  1C22 A;  5CDL A;  1QZY A;  1YJ3 A;  4IKS A;  3IG4 A;  2EA4 A;  5CLS A;  4IEC A;  2P9A A;  2EVC A;  5CNX A;  2Q95 A;  4FUK A;  5CE6 A;  3MR1 A;  1C23 A;  1XGO A;  2V3Y A;  4IF7 A;  3PKA A;  5JI6 A;  2MAT A;  3MX6 A;  3PKC A;  4RZY A;  4U6J A;  1BN5 A;  3FMQ A;  4FLJ A;  2GA2 A;  1WBQ A;  3CTZ A;  4IU6 A;  4QR8 A;  5CIK A;  2BHA A;  3CB5 A;  4FLK A;  1R58 A;  2Q96 A;  4RGZ 1;  4S00 A;  2IW2 A;  1W2M A;  1XGN A;  4U70 A;  2GG3 A;  1QXZ A;  5E5B A;  2OAZ A;  3L24 A;  1M35 A;  4PV4 A;  4U76 A;  4ZWO A;  2HOW A;  2BHB A;  3S6B A;  2BWV A;  1WL6 A;  2Q92 A;  2P99 A;  2GG2 A;  4MAT A;  5CDV A;  3BIQ A;  2BWS A;  4PNC A;  4FO7 A;  3FMR A;  2GU5 A;  4U69 A;  4U6C A;  4U6W A;  2BWX A;  5JFR A;  4A6V A;  4U6Z A;  2GG9 A;  3IU7 A;  5FCH A;  2V3Z A;  1YW8 A;  3FM3 A;  2GU7 A;  5JHU A;  1R5G A;  4OOK A;  1WLR A;  1QXY A;  1YVM A;  3ROR A;  1WKM A;  3BIT A;  4S2T P;  2B3L A;  4FKC A;  2BWU A;  2DFI A;  4R60 A;  5D6E A;  4FLI A;  4S2R P;  3TAV A;  1YW9 A;  3TB5 A;  4IDY A;  3IU8 A;  4IPA A;  1C24 A;  1C21 A;  2Q94 A;  4KM3 A;  2P98 A;  5FCF A;  2GZ5 A;  4IKR A;  2B3H A;  2BWT A;  1BOA A;  4FLL A;  1PV9 A;  2GU4 A;  3RVA A;  4S01 A;  1JAW A;  2BWW A;  4U6E A;  2EVO A;  4B28 A; 
#chains in the Genus database with same CATH topology
 2BHD A;  3D27 A;  1XGS A;  2BB7 A;  2NQ6 A;  3L7G A;  1N51 A;  2EA2 A;  2BHC A;  2BWY A;  5D6F A;  1KQ9 A;  2GGB A;  4A6W A;  2GG5 A;  3BIP A;  4JUQ A;  2Q93 A;  4U75 A;  2G6P A;  2OKN A;  4ZWU A;  2BH3 A;  2EVM A;  2GTX A;  1C27 A;  3PKD A;  4IKU A;  4FO8 A;  1B6A A;  1O0X A;  4ZWP A;  4RZZ A;  1W7V A;  4HXX A;  1XGM A;  3Q6D A;  3IU9 A;  4EGE A;  2GG8 A;  4Z7M A;  2GU6 A;  2ZSG A;  2B3K A;  1WY2 A;  3CB6 A;  2Q8K A;  3PKB A;  3MAT A;  1MAT A;  3PKE A;  1KQ0 A;  1WL9 A;  2V3X A;  4U1B A;  1A16 A;  2V6C A;  4U71 A;  1KP0 A;  2GGC A;  1XNZ A;  1QXW A;  1R5H A;  2ADU A;  4IKT A;  4U73 A;  5CDE A;  2NQ7 A;  4ZNG A;  1WN1 A;  1Y1N A;  1CHM A;  1B59 A;  2GG0 A;  2GG7 A;  2BN7 A;  1YW7 A;  1C22 A;  5CDL A;  1QZY A;  1YJ3 A;  4IKS A;  3IG4 A;  2EA4 A;  5CLS A;  4IEC A;  2P9A A;  2EVC A;  5CNX A;  2Q95 A;  4FUK A;  5CE6 A;  3MR1 A;  1C23 A;  1XGO A;  2V3Y A;  4IF7 A;  3PKA A;  5JI6 A;  2MAT A;  3MX6 A;  3PKC A;  4RZY A;  4U6J A;  1BN5 A;  3FMQ A;  4FLJ A;  2GA2 A;  1WBQ A;  3CTZ A;  4IU6 A;  4QR8 A;  5CIK A;  2BHA A;  3CB5 A;  4FLK A;  1R58 A;  2Q96 A;  4RGZ 1;  4S00 A;  2IW2 A;  1W2M A;  1XGN A;  4U70 A;  2GG3 A;  1QXZ A;  5E5B A;  2OAZ A;  3L24 A;  1M35 A;  4PV4 A;  4U76 A;  4ZWO A;  2HOW A;  2BHB A;  3S6B A;  2BWV A;  1WL6 A;  2Q92 A;  2P99 A;  2GG2 A;  4MAT A;  5CDV A;  3BIQ A;  2BWS A;  4PNC A;  4FO7 A;  3FMR A;  2GU5 A;  4U69 A;  4U6C A;  4U6W A;  2BWX A;  5JFR A;  4A6V A;  4U6Z A;  2GG9 A;  3IU7 A;  5FCH A;  2V3Z A;  1YW8 A;  3FM3 A;  2GU7 A;  5JHU A;  1R5G A;  4OOK A;  1WLR A;  1QXY A;  1YVM A;  3ROR A;  1WKM A;  3BIT A;  4S2T P;  2B3L A;  4FKC A;  2BWU A;  2DFI A;  4R60 A;  5D6E A;  4FLI A;  4S2R P;  3TAV A;  1YW9 A;  3TB5 A;  4IDY A;  3IU8 A;  4IPA A;  1C24 A;  1C21 A;  2Q94 A;  4KM3 A;  2P98 A;  5FCF A;  2GZ5 A;  4IKR A;  2B3H A;  2BWT A;  1BOA A;  4FLL A;  1PV9 A;  2GU4 A;  3RVA A;  4S01 A;  1JAW A;  2BWW A;  4U6E A;  2EVO A;  4B28 A; 
#chains in the Genus database with same CATH homology
 2BHD A;  3D27 A;  1XGS A;  2BB7 A;  2NQ6 A;  3L7G A;  1N51 A;  2EA2 A;  2BHC A;  2BWY A;  5D6F A;  1KQ9 A;  2GGB A;  4A6W A;  2GG5 A;  3BIP A;  4JUQ A;  2Q93 A;  4U75 A;  2G6P A;  2OKN A;  4ZWU A;  2BH3 A;  2EVM A;  2GTX A;  1C27 A;  3PKD A;  4IKU A;  4FO8 A;  1B6A A;  1O0X A;  4ZWP A;  4RZZ A;  1W7V A;  4HXX A;  1XGM A;  3Q6D A;  3IU9 A;  4EGE A;  2GG8 A;  4Z7M A;  2GU6 A;  2ZSG A;  2B3K A;  1WY2 A;  3CB6 A;  2Q8K A;  3PKB A;  3MAT A;  1MAT A;  3PKE A;  1KQ0 A;  1WL9 A;  2V3X A;  4U1B A;  1A16 A;  2V6C A;  4U71 A;  1KP0 A;  2GGC A;  1XNZ A;  1QXW A;  1R5H A;  2ADU A;  4IKT A;  4U73 A;  5CDE A;  2NQ7 A;  4ZNG A;  1WN1 A;  1Y1N A;  1CHM A;  1B59 A;  2GG0 A;  2GG7 A;  2BN7 A;  1YW7 A;  1C22 A;  5CDL A;  1QZY A;  1YJ3 A;  4IKS A;  3IG4 A;  2EA4 A;  5CLS A;  4IEC A;  2P9A A;  2EVC A;  5CNX A;  2Q95 A;  4FUK A;  5CE6 A;  3MR1 A;  1C23 A;  1XGO A;  2V3Y A;  4IF7 A;  3PKA A;  5JI6 A;  2MAT A;  3MX6 A;  3PKC A;  4RZY A;  4U6J A;  1BN5 A;  3FMQ A;  4FLJ A;  2GA2 A;  1WBQ A;  3CTZ A;  4IU6 A;  4QR8 A;  5CIK A;  2BHA A;  3CB5 A;  4FLK A;  1R58 A;  2Q96 A;  4RGZ 1;  4S00 A;  2IW2 A;  1W2M A;  1XGN A;  4U70 A;  2GG3 A;  1QXZ A;  5E5B A;  2OAZ A;  3L24 A;  1M35 A;  4PV4 A;  4U76 A;  4ZWO A;  2HOW A;  2BHB A;  3S6B A;  2BWV A;  1WL6 A;  2Q92 A;  2P99 A;  2GG2 A;  4MAT A;  5CDV A;  3BIQ A;  2BWS A;  4PNC A;  4FO7 A;  3FMR A;  2GU5 A;  4U69 A;  4U6C A;  4U6W A;  2BWX A;  5JFR A;  4A6V A;  4U6Z A;  2GG9 A;  3IU7 A;  5FCH A;  2V3Z A;  1YW8 A;  3FM3 A;  2GU7 A;  5JHU A;  1R5G A;  4OOK A;  1WLR A;  1QXY A;  1YVM A;  3ROR A;  1WKM A;  3BIT A;  4S2T P;  2B3L A;  4FKC A;  2BWU A;  2DFI A;  4R60 A;  5D6E A;  4FLI A;  4S2R P;  3TAV A;  1YW9 A;  3TB5 A;  4IDY A;  3IU8 A;  4IPA A;  1C24 A;  1C21 A;  2Q94 A;  4KM3 A;  2P98 A;  5FCF A;  2GZ5 A;  4IKR A;  2B3H A;  2BWT A;  1BOA A;  4FLL A;  1PV9 A;  2GU4 A;  3RVA A;  4S01 A;  1JAW A;  2BWW A;  4U6E A;  2EVO A;  4B28 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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