3PKCA

M. tuberculosis metap with bengamide analog y08, in mn form
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
281
structure length
281
Chain Sequence
b'RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTC'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 86
structure length 281
sequence length 281
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkcA01
2EA4A 2BWVA 1XGNA 2EVMA 2ADUA 5CIKA 1YW9A 2GG5A 3MATA 4IPAA 4OOKA 4IKUA 1WLRA 4A6WA 3PKEA 5CDVA 3CB6A 5E5BA 5JI6A 1JAWA 2BWSA 1XNZA 2GTXA 2P98A 3IU9A 4IECA 2B3LA 2Q93A 4IU6A 1N51A 1C23A 2P99A 3S6BA 3FMRA 2GA2A 2Q92A 2NQ7A 2BH3A 4U6WA 2B3HA 2GGCA 3MR1A 3PKDA 1YJ3A 2BWYA 2EA2A 2B3KA 5JHUA 5D6EA 5FCHA 1WL9A 1XGOA 2GU7A 4ZWOA 1QZYA 1B59A 3Q6DA 4HXXA 3L24A 4U76A 1YW7A 2GU4A 2Q95A 3PKBA 4ZWPA 1C24A 4IDYA 2GG9A 4IKRA 1KQ0A 3RORA 1XGMA 3CTZA 4IF7A 2GG2A 2OAZA 2GGBA 5CNXA 2GU5A 3TAVA 1XGSA 4U6JA 4U6EA 2P9AA 1B6AA 1QXZA 2BWWA 2V3ZA 2GG7A 1QXYA 4U70A 2BB7A 1WL6A 2Q94A 4U6CA 1C21A 4R60A 4S2TP 1QXWA 4S00A 4A6VA 2GU6A 3D27A 2NQ6A 4U71A 3IU8A 3FMQA 1BOAA 4PNCA 2BHAA 4EGEA 4FO8A 1C27A 4S2RP 1M35A 2BHCA 2BN7A 3IG4A 5CDLA 1KQ9A 2BHDA 4FLJA 2ZSGA 4QR8A 4FLLA 2BWXA 5CE6A 1KP0A 1Y1NA 4PV4A 1R5GA 3TB5A 4FKCA 2BWUA 3IU7A 2BHBA 2V6CA 4RZZA 5CLSA 1WKMA 3BITA 4S01A 5FCFA 1WN1A 2V3YA 3RVAA 4ZNGA 2BWTA 2MATA 1MATA 4FLIA 3PKAA 3FM3A 4FUKA 3BIQA 4Z7MA 1YW8A 1WY2A 4IKSA 4U69A 4B28A 4MATA 4KM3A 1BN5A 1R58A 2GG0A 4ZWUA 1PV9A 2DFIA 4FLKA 2GG3A 5JFRA 1WBQA 4JUQA 4RZYA 2G6PA 1O0XA 1R5HA 5D6FA 1CHMA 3MX6A 1C22A 2EVCA 4U1BA 2GZ5A 4U73A 2EVOA 2HOWA 2IW2A 4FO7A 1W7VA 1W2MA 3CB5A 3L7GA 3PKCA 4RGZ1 4U75A 2Q96A 2OKNA 1A16A 3BIPA 4IKTA 5CDEA 2V3XA 2Q8KA 2GG8A 4U6ZA 1YVMA
chains in the Genus database with same CATH superfamily
2EA4A 2BWVA 1XGNA 2EVMA 2ADUA 5CIKA 1YW9A 2GG5A 3MATA 4IPAA 4OOKA 4IKUA 1WLRA 4A6WA 3PKEA 5CDVA 3CB6A 5E5BA 5JI6A 1JAWA 2BWSA 1XNZA 2GTXA 2P98A 3IU9A 4IECA 2B3LA 2Q93A 4IU6A 1N51A 1C23A 2P99A 3S6BA 3FMRA 2GA2A 2Q92A 2NQ7A 2BH3A 4U6WA 2B3HA 2GGCA 3MR1A 3PKDA 1YJ3A 2BWYA 2EA2A 2B3KA 5JHUA 5D6EA 5FCHA 1WL9A 1XGOA 2GU7A 4ZWOA 1QZYA 1B59A 3Q6DA 4HXXA 3L24A 4U76A 1YW7A 2GU4A 2Q95A 3PKBA 4ZWPA 1C24A 4IDYA 2GG9A 4IKRA 1KQ0A 3RORA 1XGMA 3CTZA 4IF7A 2GG2A 2OAZA 2GGBA 5CNXA 2GU5A 3TAVA 1XGSA 4U6JA 4U6EA 2P9AA 1B6AA 1QXZA 2BWWA 2V3ZA 2GG7A 1QXYA 4U70A 2BB7A 1WL6A 2Q94A 4U6CA 1C21A 4R60A 4S2TP 1QXWA 4S00A 4A6VA 2GU6A 3D27A 2NQ6A 4U71A 3IU8A 3FMQA 1BOAA 4PNCA 2BHAA 4EGEA 4FO8A 1C27A 4S2RP 1M35A 2BHCA 2BN7A 3IG4A 5CDLA 1KQ9A 2BHDA 4FLJA 2ZSGA 4QR8A 4FLLA 2BWXA 5CE6A 1KP0A 1Y1NA 4PV4A 1R5GA 3TB5A 4FKCA 2BWUA 3IU7A 2BHBA 2V6CA 4RZZA 5CLSA 1WKMA 3BITA 4S01A 5FCFA 1WN1A 2V3YA 3RVAA 4ZNGA 2BWTA 2MATA 1MATA 4FLIA 3PKAA 3FM3A 4FUKA 3BIQA 4Z7MA 1YW8A 1WY2A 4IKSA 4U69A 4B28A 4MATA 4KM3A 1BN5A 1R58A 2GG0A 4ZWUA 1PV9A 2DFIA 4FLKA 2GG3A 5JFRA 1WBQA 4JUQA 4RZYA 2G6PA 1O0XA 1R5HA 5D6FA 1CHMA 3MX6A 1C22A 2EVCA 4U1BA 2GZ5A 4U73A 2EVOA 2HOWA 2IW2A 4FO7A 1W7VA 1W2MA 3CB5A 3L7GA 3PKCA 4RGZ1 4U75A 2Q96A 2OKNA 1A16A 3BIPA 4IKTA 5CDEA 2V3XA 2Q8KA 2GG8A 4U6ZA 1YVMA
chains in the Genus database with same CATH topology
2EA4A 2BWVA 1XGNA 2EVMA 2ADUA 5CIKA 1YW9A 2GG5A 3MATA 4IPAA 4OOKA 4IKUA 1WLRA 4A6WA 3PKEA 5CDVA 3CB6A 5E5BA 5JI6A 1JAWA 2BWSA 1XNZA 2GTXA 2P98A 3IU9A 4IECA 2B3LA 2Q93A 4IU6A 1N51A 1C23A 2P99A 3S6BA 3FMRA 2GA2A 2Q92A 2NQ7A 2BH3A 4U6WA 2B3HA 2GGCA 3MR1A 3PKDA 1YJ3A 2BWYA 2EA2A 2B3KA 5JHUA 5D6EA 5FCHA 1WL9A 1XGOA 2GU7A 4ZWOA 1QZYA 1B59A 3Q6DA 4HXXA 3L24A 4U76A 1YW7A 2GU4A 2Q95A 3PKBA 4ZWPA 1C24A 4IDYA 2GG9A 4IKRA 1KQ0A 3RORA 1XGMA 3CTZA 4IF7A 2GG2A 2OAZA 2GGBA 5CNXA 2GU5A 3TAVA 1XGSA 4U6JA 4U6EA 2P9AA 1B6AA 1QXZA 2BWWA 2V3ZA 2GG7A 1QXYA 4U70A 2BB7A 1WL6A 2Q94A 4U6CA 1C21A 4R60A 4S2TP 1QXWA 4S00A 4A6VA 2GU6A 3D27A 2NQ6A 4U71A 3IU8A 3FMQA 1BOAA 4PNCA 2BHAA 4EGEA 4FO8A 1C27A 4S2RP 1M35A 2BHCA 2BN7A 3IG4A 5CDLA 1KQ9A 2BHDA 4FLJA 2ZSGA 4QR8A 4FLLA 2BWXA 5CE6A 1KP0A 1Y1NA 4PV4A 1R5GA 3TB5A 4FKCA 2BWUA 3IU7A 2BHBA 2V6CA 4RZZA 5CLSA 1WKMA 3BITA 4S01A 5FCFA 1WN1A 2V3YA 3RVAA 4ZNGA 2BWTA 2MATA 1MATA 4FLIA 3PKAA 3FM3A 4FUKA 3BIQA 4Z7MA 1YW8A 1WY2A 4IKSA 4U69A 4B28A 4MATA 4KM3A 1BN5A 1R58A 2GG0A 4ZWUA 1PV9A 2DFIA 4FLKA 2GG3A 5JFRA 1WBQA 4JUQA 4RZYA 2G6PA 1O0XA 1R5HA 5D6FA 1CHMA 3MX6A 1C22A 2EVCA 4U1BA 2GZ5A 4U73A 2EVOA 2HOWA 2IW2A 4FO7A 1W7VA 1W2MA 3CB5A 3L7GA 3PKCA 4RGZ1 4U75A 2Q96A 2OKNA 1A16A 3BIPA 4IKTA 5CDEA 2V3XA 2Q8KA 2GG8A 4U6ZA 1YVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EA4 A;  2BWV A;  1XGN A;  2EVM A;  2ADU A;  5CIK A;  1YW9 A;  2GG5 A;  3MAT A;  4IPA A;  4OOK A;  4IKU A;  1WLR A;  4A6W A;  3PKE A;  5CDV A;  3CB6 A;  5E5B A;  5JI6 A;  1JAW A;  2BWS A;  1XNZ A;  2GTX A;  2P98 A;  3IU9 A;  4IEC A;  2B3L A;  2Q93 A;  4IU6 A;  1N51 A;  1C23 A;  2P99 A;  3S6B A;  3FMR A;  2GA2 A;  2Q92 A;  2NQ7 A;  2BH3 A;  4U6W A;  2B3H A;  2GGC A;  3MR1 A;  3PKD A;  1YJ3 A;  2BWY A;  2EA2 A;  2B3K A;  5JHU A;  5D6E A;  5FCH A;  1WL9 A;  1XGO A;  2GU7 A;  4ZWO A;  1QZY A;  1B59 A;  3Q6D A;  4HXX A;  3L24 A;  4U76 A;  1YW7 A;  2GU4 A;  2Q95 A;  3PKB A;  4ZWP A;  1C24 A;  4IDY A;  2GG9 A;  4IKR A;  1KQ0 A;  3ROR A;  1XGM A;  3CTZ A;  4IF7 A;  2GG2 A;  2OAZ A;  2GGB A;  5CNX A;  2GU5 A;  3TAV A;  1XGS A;  4U6J A;  4U6E A;  2P9A A;  1B6A A;  1QXZ A;  2BWW A;  2V3Z A;  2GG7 A;  1QXY A;  4U70 A;  2BB7 A;  1WL6 A;  2Q94 A;  4U6C A;  1C21 A;  4R60 A;  4S2T P;  1QXW A;  4S00 A;  4A6V A;  2GU6 A;  3D27 A;  2NQ6 A;  4U71 A;  3IU8 A;  3FMQ A;  1BOA A;  4PNC A;  2BHA A;  4EGE A;  4FO8 A;  1C27 A;  4S2R P;  1M35 A;  2BHC A;  2BN7 A;  3IG4 A;  5CDL A;  1KQ9 A;  2BHD A;  4FLJ A;  2ZSG A;  4QR8 A;  4FLL A;  2BWX A;  5CE6 A;  1KP0 A;  1Y1N A;  4PV4 A;  1R5G A;  3TB5 A;  4FKC A;  2BWU A;  3IU7 A;  2BHB A;  2V6C A;  4RZZ A;  5CLS A;  1WKM A;  3BIT A;  4S01 A;  5FCF A;  1WN1 A;  2V3Y A;  3RVA A;  4ZNG A;  2BWT A;  2MAT A;  1MAT A;  4FLI A;  3PKA A;  3FM3 A;  4FUK A;  3BIQ A;  4Z7M A;  1YW8 A;  1WY2 A;  4IKS A;  4U69 A;  4B28 A;  4MAT A;  4KM3 A;  1BN5 A;  1R58 A;  2GG0 A;  4ZWU A;  1PV9 A;  2DFI A;  4FLK A;  2GG3 A;  5JFR A;  1WBQ A;  4JUQ A;  4RZY A;  2G6P A;  1O0X A;  1R5H A;  5D6F A;  1CHM A;  3MX6 A;  1C22 A;  2EVC A;  4U1B A;  2GZ5 A;  4U73 A;  2EVO A;  2HOW A;  2IW2 A;  4FO7 A;  1W7V A;  1W2M A;  3CB5 A;  3L7G A;  3PKC A;  4RGZ 1;  4U75 A;  2Q96 A;  2OKN A;  1A16 A;  3BIP A;  4IKT A;  5CDE A;  2V3X A;  2Q8K A;  2GG8 A;  4U6Z A;  1YVM A; 
#chains in the Genus database with same CATH topology
 2EA4 A;  2BWV A;  1XGN A;  2EVM A;  2ADU A;  5CIK A;  1YW9 A;  2GG5 A;  3MAT A;  4IPA A;  4OOK A;  4IKU A;  1WLR A;  4A6W A;  3PKE A;  5CDV A;  3CB6 A;  5E5B A;  5JI6 A;  1JAW A;  2BWS A;  1XNZ A;  2GTX A;  2P98 A;  3IU9 A;  4IEC A;  2B3L A;  2Q93 A;  4IU6 A;  1N51 A;  1C23 A;  2P99 A;  3S6B A;  3FMR A;  2GA2 A;  2Q92 A;  2NQ7 A;  2BH3 A;  4U6W A;  2B3H A;  2GGC A;  3MR1 A;  3PKD A;  1YJ3 A;  2BWY A;  2EA2 A;  2B3K A;  5JHU A;  5D6E A;  5FCH A;  1WL9 A;  1XGO A;  2GU7 A;  4ZWO A;  1QZY A;  1B59 A;  3Q6D A;  4HXX A;  3L24 A;  4U76 A;  1YW7 A;  2GU4 A;  2Q95 A;  3PKB A;  4ZWP A;  1C24 A;  4IDY A;  2GG9 A;  4IKR A;  1KQ0 A;  3ROR A;  1XGM A;  3CTZ A;  4IF7 A;  2GG2 A;  2OAZ A;  2GGB A;  5CNX A;  2GU5 A;  3TAV A;  1XGS A;  4U6J A;  4U6E A;  2P9A A;  1B6A A;  1QXZ A;  2BWW A;  2V3Z A;  2GG7 A;  1QXY A;  4U70 A;  2BB7 A;  1WL6 A;  2Q94 A;  4U6C A;  1C21 A;  4R60 A;  4S2T P;  1QXW A;  4S00 A;  4A6V A;  2GU6 A;  3D27 A;  2NQ6 A;  4U71 A;  3IU8 A;  3FMQ A;  1BOA A;  4PNC A;  2BHA A;  4EGE A;  4FO8 A;  1C27 A;  4S2R P;  1M35 A;  2BHC A;  2BN7 A;  3IG4 A;  5CDL A;  1KQ9 A;  2BHD A;  4FLJ A;  2ZSG A;  4QR8 A;  4FLL A;  2BWX A;  5CE6 A;  1KP0 A;  1Y1N A;  4PV4 A;  1R5G A;  3TB5 A;  4FKC A;  2BWU A;  3IU7 A;  2BHB A;  2V6C A;  4RZZ A;  5CLS A;  1WKM A;  3BIT A;  4S01 A;  5FCF A;  1WN1 A;  2V3Y A;  3RVA A;  4ZNG A;  2BWT A;  2MAT A;  1MAT A;  4FLI A;  3PKA A;  3FM3 A;  4FUK A;  3BIQ A;  4Z7M A;  1YW8 A;  1WY2 A;  4IKS A;  4U69 A;  4B28 A;  4MAT A;  4KM3 A;  1BN5 A;  1R58 A;  2GG0 A;  4ZWU A;  1PV9 A;  2DFI A;  4FLK A;  2GG3 A;  5JFR A;  1WBQ A;  4JUQ A;  4RZY A;  2G6P A;  1O0X A;  1R5H A;  5D6F A;  1CHM A;  3MX6 A;  1C22 A;  2EVC A;  4U1B A;  2GZ5 A;  4U73 A;  2EVO A;  2HOW A;  2IW2 A;  4FO7 A;  1W7V A;  1W2M A;  3CB5 A;  3L7G A;  3PKC A;  4RGZ 1;  4U75 A;  2Q96 A;  2OKN A;  1A16 A;  3BIP A;  4IKT A;  5CDE A;  2V3X A;  2Q8K A;  2GG8 A;  4U6Z A;  1YVM A; 
#chains in the Genus database with same CATH homology
 2EA4 A;  2BWV A;  1XGN A;  2EVM A;  2ADU A;  5CIK A;  1YW9 A;  2GG5 A;  3MAT A;  4IPA A;  4OOK A;  4IKU A;  1WLR A;  4A6W A;  3PKE A;  5CDV A;  3CB6 A;  5E5B A;  5JI6 A;  1JAW A;  2BWS A;  1XNZ A;  2GTX A;  2P98 A;  3IU9 A;  4IEC A;  2B3L A;  2Q93 A;  4IU6 A;  1N51 A;  1C23 A;  2P99 A;  3S6B A;  3FMR A;  2GA2 A;  2Q92 A;  2NQ7 A;  2BH3 A;  4U6W A;  2B3H A;  2GGC A;  3MR1 A;  3PKD A;  1YJ3 A;  2BWY A;  2EA2 A;  2B3K A;  5JHU A;  5D6E A;  5FCH A;  1WL9 A;  1XGO A;  2GU7 A;  4ZWO A;  1QZY A;  1B59 A;  3Q6D A;  4HXX A;  3L24 A;  4U76 A;  1YW7 A;  2GU4 A;  2Q95 A;  3PKB A;  4ZWP A;  1C24 A;  4IDY A;  2GG9 A;  4IKR A;  1KQ0 A;  3ROR A;  1XGM A;  3CTZ A;  4IF7 A;  2GG2 A;  2OAZ A;  2GGB A;  5CNX A;  2GU5 A;  3TAV A;  1XGS A;  4U6J A;  4U6E A;  2P9A A;  1B6A A;  1QXZ A;  2BWW A;  2V3Z A;  2GG7 A;  1QXY A;  4U70 A;  2BB7 A;  1WL6 A;  2Q94 A;  4U6C A;  1C21 A;  4R60 A;  4S2T P;  1QXW A;  4S00 A;  4A6V A;  2GU6 A;  3D27 A;  2NQ6 A;  4U71 A;  3IU8 A;  3FMQ A;  1BOA A;  4PNC A;  2BHA A;  4EGE A;  4FO8 A;  1C27 A;  4S2R P;  1M35 A;  2BHC A;  2BN7 A;  3IG4 A;  5CDL A;  1KQ9 A;  2BHD A;  4FLJ A;  2ZSG A;  4QR8 A;  4FLL A;  2BWX A;  5CE6 A;  1KP0 A;  1Y1N A;  4PV4 A;  1R5G A;  3TB5 A;  4FKC A;  2BWU A;  3IU7 A;  2BHB A;  2V6C A;  4RZZ A;  5CLS A;  1WKM A;  3BIT A;  4S01 A;  5FCF A;  1WN1 A;  2V3Y A;  3RVA A;  4ZNG A;  2BWT A;  2MAT A;  1MAT A;  4FLI A;  3PKA A;  3FM3 A;  4FUK A;  3BIQ A;  4Z7M A;  1YW8 A;  1WY2 A;  4IKS A;  4U69 A;  4B28 A;  4MAT A;  4KM3 A;  1BN5 A;  1R58 A;  2GG0 A;  4ZWU A;  1PV9 A;  2DFI A;  4FLK A;  2GG3 A;  5JFR A;  1WBQ A;  4JUQ A;  4RZY A;  2G6P A;  1O0X A;  1R5H A;  5D6F A;  1CHM A;  3MX6 A;  1C22 A;  2EVC A;  4U1B A;  2GZ5 A;  4U73 A;  2EVO A;  2HOW A;  2IW2 A;  4FO7 A;  1W7V A;  1W2M A;  3CB5 A;  3L7G A;  3PKC A;  4RGZ 1;  4U75 A;  2Q96 A;  2OKN A;  1A16 A;  3BIP A;  4IKT A;  5CDE A;  2V3X A;  2Q8K A;  2GG8 A;  4U6Z A;  1YVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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