2Q92A

E. coli methionine aminopeptidase mn-form with inhibitor b23
Total Genus 84
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
source organism Escherichia coli
publication title Structural analysis of inhibition of E. coli methionine aminopeptidase: implication of loop flexibility in selective inhibition of bacterial enzymes.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 84
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2007-06-12

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2q92A00
2V3YA 2BWYA 2P9AA 4KM3A 2EVMA 3BITA 2BHCA 1WN1A 2NQ6A 2GG3A 3PKEA 4FLJA 4S2TP 4R60A 3IU7A 1YJ3A 1B59A 4OOKA 2NQ7A 2V3XA 4A6VA 5CNXA 2BHBA 1KP0A 2MATA 2GGCA 1O0XA 4QR8A 4EGEA 4ZNGA 4Z7MA 4IDYA 5CDVA 5CDLA 1R5HA 3PKDA 4U1BA 1YW8A 1BOAA 4FO8A 4MATA 2EVCA 2GU5A 4U6CA 1XGNA 4U69A 1WL6A 4U6ZA 1B6AA 2GG7A 4IF7A 3IU9A 4A6WA 4IPAA 2Q95A 2GZ5A 1CHMA 4ZWPA 4RZZA 1KQ0A 2Q92A 3PKAA 2BB7A 2DFIA 2GU6A 4FUKA 1MATA 2GTXA 1C24A 3L24A 3D27A 4IKRA 3MR1A 4IU6A 5CLSA 5JHUA 3Q6DA 2EVOA 3FM3A 5FCFA 5E5BA 2B3HA 5D6FA 3CB6A 2BWTA 4U75A 4FLKA 1M35A 2GGBA 2ADUA 3BIQA 2OAZA 2B3KA 3L7GA 4IKTA 2BHDA 4U6WA 4B28A 1PV9A 2GG2A 2ZSGA 4S01A 4S00A 1WL9A 2Q96A 2P99A 1C23A 4U73A 4U71A 1WKMA 2V3ZA 1YVMA 2BWSA 2G6PA 3TAVA 1R5GA 2GU4A 1YW7A 4FO7A 3TB5A 2GG9A 2BWXA 5JI6A 2BWWA 4FLLA 4ZWOA 1W2MA 3MATA 4IKUA 2Q94A 2BN7A 2P98A 3CTZA 2OKNA 4FLIA 3RORA 2GG0A 1R58A 2GG8A 4RZYA 1XGSA 4U6EA 4U76A 4U70A 5JFRA 1QXZA 1XGOA 2BWVA 3PKBA 3PKCA 4S2RP 4RGZ1 1WBQA 3FMRA 2BHAA 1W7VA 4JUQA 2BH3A 3IG4A 2GA2A 1KQ9A 3RVAA 4U6JA 1BN5A 1WLRA 2GU7A 3IU8A 4IECA 1Y1NA 1XNZA 4FKCA 1YW9A 4HXXA 2GG5A 2IW2A 1JAWA 1C22A 5D6EA 3BIPA 2HOWA 2Q93A 2EA4A 5CDEA 1QZYA 3MX6A 4ZWUA 1WY2A 4PNCA 1XGMA 1N51A 3FMQA 2V6CA 4IKSA 2BWUA 1QXYA 1C27A 1QXWA 3CB5A 5CE6A 1C21A 2EA2A 5FCHA 5CIKA 2B3LA 3S6BA 4PV4A 2Q8KA 1A16A
chains in the Genus database with same CATH superfamily
2V3YA 2BWYA 2P9AA 4KM3A 2EVMA 3BITA 2BHCA 1WN1A 2NQ6A 2GG3A 3PKEA 4FLJA 4S2TP 4R60A 3IU7A 1YJ3A 1B59A 4OOKA 2NQ7A 2V3XA 4A6VA 5CNXA 2BHBA 1KP0A 2MATA 2GGCA 1O0XA 4QR8A 4EGEA 4ZNGA 4Z7MA 4IDYA 5CDVA 5CDLA 1R5HA 3PKDA 4U1BA 1YW8A 1BOAA 4FO8A 4MATA 2EVCA 2GU5A 4U6CA 1XGNA 4U69A 1WL6A 4U6ZA 1B6AA 2GG7A 4IF7A 3IU9A 4A6WA 4IPAA 2Q95A 2GZ5A 1CHMA 4ZWPA 4RZZA 1KQ0A 2Q92A 3PKAA 2BB7A 2DFIA 2GU6A 4FUKA 1MATA 2GTXA 1C24A 3L24A 3D27A 4IKRA 3MR1A 4IU6A 5CLSA 5JHUA 3Q6DA 2EVOA 3FM3A 5FCFA 5E5BA 2B3HA 5D6FA 3CB6A 2BWTA 4U75A 4FLKA 1M35A 2GGBA 2ADUA 3BIQA 2OAZA 2B3KA 3L7GA 4IKTA 2BHDA 4U6WA 4B28A 1PV9A 2GG2A 2ZSGA 4S01A 4S00A 1WL9A 2Q96A 2P99A 1C23A 4U73A 4U71A 1WKMA 2V3ZA 1YVMA 2BWSA 2G6PA 3TAVA 1R5GA 2GU4A 1YW7A 4FO7A 3TB5A 2GG9A 2BWXA 5JI6A 2BWWA 4FLLA 4ZWOA 1W2MA 3MATA 4IKUA 2Q94A 2BN7A 2P98A 3CTZA 2OKNA 4FLIA 3RORA 2GG0A 1R58A 2GG8A 4RZYA 1XGSA 4U6EA 4U76A 4U70A 5JFRA 1QXZA 1XGOA 2BWVA 3PKBA 3PKCA 4S2RP 4RGZ1 1WBQA 3FMRA 2BHAA 1W7VA 4JUQA 2BH3A 3IG4A 2GA2A 1KQ9A 3RVAA 4U6JA 1BN5A 1WLRA 2GU7A 3IU8A 4IECA 1Y1NA 1XNZA 4FKCA 1YW9A 4HXXA 2GG5A 2IW2A 1JAWA 1C22A 5D6EA 3BIPA 2HOWA 2Q93A 2EA4A 5CDEA 1QZYA 3MX6A 4ZWUA 1WY2A 4PNCA 1XGMA 1N51A 3FMQA 2V6CA 4IKSA 2BWUA 1QXYA 1C27A 1QXWA 3CB5A 5CE6A 1C21A 2EA2A 5FCHA 5CIKA 2B3LA 3S6BA 4PV4A 2Q8KA 1A16A
chains in the Genus database with same CATH topology
2V3YA 2BWYA 2P9AA 4KM3A 2EVMA 3BITA 2BHCA 1WN1A 2NQ6A 2GG3A 3PKEA 4FLJA 4S2TP 4R60A 3IU7A 1YJ3A 1B59A 4OOKA 2NQ7A 2V3XA 4A6VA 5CNXA 2BHBA 1KP0A 2MATA 2GGCA 1O0XA 4QR8A 4EGEA 4ZNGA 4Z7MA 4IDYA 5CDVA 5CDLA 1R5HA 3PKDA 4U1BA 1YW8A 1BOAA 4FO8A 4MATA 2EVCA 2GU5A 4U6CA 1XGNA 4U69A 1WL6A 4U6ZA 1B6AA 2GG7A 4IF7A 3IU9A 4A6WA 4IPAA 2Q95A 2GZ5A 1CHMA 4ZWPA 4RZZA 1KQ0A 2Q92A 3PKAA 2BB7A 2DFIA 2GU6A 4FUKA 1MATA 2GTXA 1C24A 3L24A 3D27A 4IKRA 3MR1A 4IU6A 5CLSA 5JHUA 3Q6DA 2EVOA 3FM3A 5FCFA 5E5BA 2B3HA 5D6FA 3CB6A 2BWTA 4U75A 4FLKA 1M35A 2GGBA 2ADUA 3BIQA 2OAZA 2B3KA 3L7GA 4IKTA 2BHDA 4U6WA 4B28A 1PV9A 2GG2A 2ZSGA 4S01A 4S00A 1WL9A 2Q96A 2P99A 1C23A 4U73A 4U71A 1WKMA 2V3ZA 1YVMA 2BWSA 2G6PA 3TAVA 1R5GA 2GU4A 1YW7A 4FO7A 3TB5A 2GG9A 2BWXA 5JI6A 2BWWA 4FLLA 4ZWOA 1W2MA 3MATA 4IKUA 2Q94A 2BN7A 2P98A 3CTZA 2OKNA 4FLIA 3RORA 2GG0A 1R58A 2GG8A 4RZYA 1XGSA 4U6EA 4U76A 4U70A 5JFRA 1QXZA 1XGOA 2BWVA 3PKBA 3PKCA 4S2RP 4RGZ1 1WBQA 3FMRA 2BHAA 1W7VA 4JUQA 2BH3A 3IG4A 2GA2A 1KQ9A 3RVAA 4U6JA 1BN5A 1WLRA 2GU7A 3IU8A 4IECA 1Y1NA 1XNZA 4FKCA 1YW9A 4HXXA 2GG5A 2IW2A 1JAWA 1C22A 5D6EA 3BIPA 2HOWA 2Q93A 2EA4A 5CDEA 1QZYA 3MX6A 4ZWUA 1WY2A 4PNCA 1XGMA 1N51A 3FMQA 2V6CA 4IKSA 2BWUA 1QXYA 1C27A 1QXWA 3CB5A 5CE6A 1C21A 2EA2A 5FCHA 5CIKA 2B3LA 3S6BA 4PV4A 2Q8KA 1A16A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2V3Y A;  2BWY A;  2P9A A;  4KM3 A;  2EVM A;  3BIT A;  2BHC A;  1WN1 A;  2NQ6 A;  2GG3 A;  3PKE A;  4FLJ A;  4S2T P;  4R60 A;  3IU7 A;  1YJ3 A;  1B59 A;  4OOK A;  2NQ7 A;  2V3X A;  4A6V A;  5CNX A;  2BHB A;  1KP0 A;  2MAT A;  2GGC A;  1O0X A;  4QR8 A;  4EGE A;  4ZNG A;  4Z7M A;  4IDY A;  5CDV A;  5CDL A;  1R5H A;  3PKD A;  4U1B A;  1YW8 A;  1BOA A;  4FO8 A;  4MAT A;  2EVC A;  2GU5 A;  4U6C A;  1XGN A;  4U69 A;  1WL6 A;  4U6Z A;  1B6A A;  2GG7 A;  4IF7 A;  3IU9 A;  4A6W A;  4IPA A;  2Q95 A;  2GZ5 A;  1CHM A;  4ZWP A;  4RZZ A;  1KQ0 A;  2Q92 A;  3PKA A;  2BB7 A;  2DFI A;  2GU6 A;  4FUK A;  1MAT A;  2GTX A;  1C24 A;  3L24 A;  3D27 A;  4IKR A;  3MR1 A;  4IU6 A;  5CLS A;  5JHU A;  3Q6D A;  2EVO A;  3FM3 A;  5FCF A;  5E5B A;  2B3H A;  5D6F A;  3CB6 A;  2BWT A;  4U75 A;  4FLK A;  1M35 A;  2GGB A;  2ADU A;  3BIQ A;  2OAZ A;  2B3K A;  3L7G A;  4IKT A;  2BHD A;  4U6W A;  4B28 A;  1PV9 A;  2GG2 A;  2ZSG A;  4S01 A;  4S00 A;  1WL9 A;  2Q96 A;  2P99 A;  1C23 A;  4U73 A;  4U71 A;  1WKM A;  2V3Z A;  1YVM A;  2BWS A;  2G6P A;  3TAV A;  1R5G A;  2GU4 A;  1YW7 A;  4FO7 A;  3TB5 A;  2GG9 A;  2BWX A;  5JI6 A;  2BWW A;  4FLL A;  4ZWO A;  1W2M A;  3MAT A;  4IKU A;  2Q94 A;  2BN7 A;  2P98 A;  3CTZ A;  2OKN A;  4FLI A;  3ROR A;  2GG0 A;  1R58 A;  2GG8 A;  4RZY A;  1XGS A;  4U6E A;  4U76 A;  4U70 A;  5JFR A;  1QXZ A;  1XGO A;  2BWV A;  3PKB A;  3PKC A;  4S2R P;  4RGZ 1;  1WBQ A;  3FMR A;  2BHA A;  1W7V A;  4JUQ A;  2BH3 A;  3IG4 A;  2GA2 A;  1KQ9 A;  3RVA A;  4U6J A;  1BN5 A;  1WLR A;  2GU7 A;  3IU8 A;  4IEC A;  1Y1N A;  1XNZ A;  4FKC A;  1YW9 A;  4HXX A;  2GG5 A;  2IW2 A;  1JAW A;  1C22 A;  5D6E A;  3BIP A;  2HOW A;  2Q93 A;  2EA4 A;  5CDE A;  1QZY A;  3MX6 A;  4ZWU A;  1WY2 A;  4PNC A;  1XGM A;  1N51 A;  3FMQ A;  2V6C A;  4IKS A;  2BWU A;  1QXY A;  1C27 A;  1QXW A;  3CB5 A;  5CE6 A;  1C21 A;  2EA2 A;  5FCH A;  5CIK A;  2B3L A;  3S6B A;  4PV4 A;  2Q8K A;  1A16 A; 
#chains in the Genus database with same CATH topology
 2V3Y A;  2BWY A;  2P9A A;  4KM3 A;  2EVM A;  3BIT A;  2BHC A;  1WN1 A;  2NQ6 A;  2GG3 A;  3PKE A;  4FLJ A;  4S2T P;  4R60 A;  3IU7 A;  1YJ3 A;  1B59 A;  4OOK A;  2NQ7 A;  2V3X A;  4A6V A;  5CNX A;  2BHB A;  1KP0 A;  2MAT A;  2GGC A;  1O0X A;  4QR8 A;  4EGE A;  4ZNG A;  4Z7M A;  4IDY A;  5CDV A;  5CDL A;  1R5H A;  3PKD A;  4U1B A;  1YW8 A;  1BOA A;  4FO8 A;  4MAT A;  2EVC A;  2GU5 A;  4U6C A;  1XGN A;  4U69 A;  1WL6 A;  4U6Z A;  1B6A A;  2GG7 A;  4IF7 A;  3IU9 A;  4A6W A;  4IPA A;  2Q95 A;  2GZ5 A;  1CHM A;  4ZWP A;  4RZZ A;  1KQ0 A;  2Q92 A;  3PKA A;  2BB7 A;  2DFI A;  2GU6 A;  4FUK A;  1MAT A;  2GTX A;  1C24 A;  3L24 A;  3D27 A;  4IKR A;  3MR1 A;  4IU6 A;  5CLS A;  5JHU A;  3Q6D A;  2EVO A;  3FM3 A;  5FCF A;  5E5B A;  2B3H A;  5D6F A;  3CB6 A;  2BWT A;  4U75 A;  4FLK A;  1M35 A;  2GGB A;  2ADU A;  3BIQ A;  2OAZ A;  2B3K A;  3L7G A;  4IKT A;  2BHD A;  4U6W A;  4B28 A;  1PV9 A;  2GG2 A;  2ZSG A;  4S01 A;  4S00 A;  1WL9 A;  2Q96 A;  2P99 A;  1C23 A;  4U73 A;  4U71 A;  1WKM A;  2V3Z A;  1YVM A;  2BWS A;  2G6P A;  3TAV A;  1R5G A;  2GU4 A;  1YW7 A;  4FO7 A;  3TB5 A;  2GG9 A;  2BWX A;  5JI6 A;  2BWW A;  4FLL A;  4ZWO A;  1W2M A;  3MAT A;  4IKU A;  2Q94 A;  2BN7 A;  2P98 A;  3CTZ A;  2OKN A;  4FLI A;  3ROR A;  2GG0 A;  1R58 A;  2GG8 A;  4RZY A;  1XGS A;  4U6E A;  4U76 A;  4U70 A;  5JFR A;  1QXZ A;  1XGO A;  2BWV A;  3PKB A;  3PKC A;  4S2R P;  4RGZ 1;  1WBQ A;  3FMR A;  2BHA A;  1W7V A;  4JUQ A;  2BH3 A;  3IG4 A;  2GA2 A;  1KQ9 A;  3RVA A;  4U6J A;  1BN5 A;  1WLR A;  2GU7 A;  3IU8 A;  4IEC A;  1Y1N A;  1XNZ A;  4FKC A;  1YW9 A;  4HXX A;  2GG5 A;  2IW2 A;  1JAW A;  1C22 A;  5D6E A;  3BIP A;  2HOW A;  2Q93 A;  2EA4 A;  5CDE A;  1QZY A;  3MX6 A;  4ZWU A;  1WY2 A;  4PNC A;  1XGM A;  1N51 A;  3FMQ A;  2V6C A;  4IKS A;  2BWU A;  1QXY A;  1C27 A;  1QXW A;  3CB5 A;  5CE6 A;  1C21 A;  2EA2 A;  5FCH A;  5CIK A;  2B3L A;  3S6B A;  4PV4 A;  2Q8K A;  1A16 A; 
#chains in the Genus database with same CATH homology
 2V3Y A;  2BWY A;  2P9A A;  4KM3 A;  2EVM A;  3BIT A;  2BHC A;  1WN1 A;  2NQ6 A;  2GG3 A;  3PKE A;  4FLJ A;  4S2T P;  4R60 A;  3IU7 A;  1YJ3 A;  1B59 A;  4OOK A;  2NQ7 A;  2V3X A;  4A6V A;  5CNX A;  2BHB A;  1KP0 A;  2MAT A;  2GGC A;  1O0X A;  4QR8 A;  4EGE A;  4ZNG A;  4Z7M A;  4IDY A;  5CDV A;  5CDL A;  1R5H A;  3PKD A;  4U1B A;  1YW8 A;  1BOA A;  4FO8 A;  4MAT A;  2EVC A;  2GU5 A;  4U6C A;  1XGN A;  4U69 A;  1WL6 A;  4U6Z A;  1B6A A;  2GG7 A;  4IF7 A;  3IU9 A;  4A6W A;  4IPA A;  2Q95 A;  2GZ5 A;  1CHM A;  4ZWP A;  4RZZ A;  1KQ0 A;  2Q92 A;  3PKA A;  2BB7 A;  2DFI A;  2GU6 A;  4FUK A;  1MAT A;  2GTX A;  1C24 A;  3L24 A;  3D27 A;  4IKR A;  3MR1 A;  4IU6 A;  5CLS A;  5JHU A;  3Q6D A;  2EVO A;  3FM3 A;  5FCF A;  5E5B A;  2B3H A;  5D6F A;  3CB6 A;  2BWT A;  4U75 A;  4FLK A;  1M35 A;  2GGB A;  2ADU A;  3BIQ A;  2OAZ A;  2B3K A;  3L7G A;  4IKT A;  2BHD A;  4U6W A;  4B28 A;  1PV9 A;  2GG2 A;  2ZSG A;  4S01 A;  4S00 A;  1WL9 A;  2Q96 A;  2P99 A;  1C23 A;  4U73 A;  4U71 A;  1WKM A;  2V3Z A;  1YVM A;  2BWS A;  2G6P A;  3TAV A;  1R5G A;  2GU4 A;  1YW7 A;  4FO7 A;  3TB5 A;  2GG9 A;  2BWX A;  5JI6 A;  2BWW A;  4FLL A;  4ZWO A;  1W2M A;  3MAT A;  4IKU A;  2Q94 A;  2BN7 A;  2P98 A;  3CTZ A;  2OKN A;  4FLI A;  3ROR A;  2GG0 A;  1R58 A;  2GG8 A;  4RZY A;  1XGS A;  4U6E A;  4U76 A;  4U70 A;  5JFR A;  1QXZ A;  1XGO A;  2BWV A;  3PKB A;  3PKC A;  4S2R P;  4RGZ 1;  1WBQ A;  3FMR A;  2BHA A;  1W7V A;  4JUQ A;  2BH3 A;  3IG4 A;  2GA2 A;  1KQ9 A;  3RVA A;  4U6J A;  1BN5 A;  1WLR A;  2GU7 A;  3IU8 A;  4IEC A;  1Y1N A;  1XNZ A;  4FKC A;  1YW9 A;  4HXX A;  2GG5 A;  2IW2 A;  1JAW A;  1C22 A;  5D6E A;  3BIP A;  2HOW A;  2Q93 A;  2EA4 A;  5CDE A;  1QZY A;  3MX6 A;  4ZWU A;  1WY2 A;  4PNC A;  1XGM A;  1N51 A;  3FMQ A;  2V6C A;  4IKS A;  2BWU A;  1QXY A;  1C27 A;  1QXW A;  3CB5 A;  5CE6 A;  1C21 A;  2EA2 A;  5FCH A;  5CIK A;  2B3L A;  3S6B A;  4PV4 A;  2Q8K A;  1A16 A;
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...
How to cite