5CNXA

Crystal structure of xaa-pro aminopeptidase from escherichia coli k12
Total Genus 121
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
121
sequence length
360
structure length
360
Chain Sequence
STLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVVISRESAHILVDSRYYVEVEARAQGYQLHLLDATNTLTTIVNQIIADEQLQTLGFEGQQVSWETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSEREIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQGYCSDMTRTLLVNGEGVSAESHLLFNVYQIVLQAQLAAISAIRPGVRCQQVDDAARRVITEAGYGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRIEDVVLVTPQGAEVLYAMPKTVLLTGE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Aminopeptidase YpdF
publication title Structures and activities of widely conserved small prokaryotic aminopeptidases-P clarify classification of M24B peptidases
pubmed doi rcsb
source organism Escherichia coli
total genus 121
structure length 360
sequence length 360
chains with identical sequence B, C
ec nomenclature ec 3.4.11.-:
pdb deposition date 2015-07-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5cnxA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5cnxA02
2EA4A 4QR8A 4KM3A 1R5GA 2NQ7A 3OOOA 3QOCA 2GU5A 4RZZA 2GA2A 1M35A 2V3XA 1BN5A 4U75A 1R58A 3MR1A 3PEBA 2Q8KA 3PKBA 1QXYA 4IF7A 4RZYA 2HOWA 2GGCA 1A16A 5CLSA 4R60A 4S01A 2OKNA 1KP0A 2EVMA 2GG9A 2GG8A 3PKDA 2BHAA 4B28A 4S2RP 1WBQA 1N51A 1YVMA 4A6WA 3O5VA 3PKEA 2GG3A 2Q93A 4FLLA 4JUQA 4S00A 4IU6A 1WKMA 4S2TP 1MATA 4U6EA 4U71A 2BB7A 2GU4A 2BWWA 2BH3A 3IL0A 4IECA 3BIQA 1BOAA 3FM3A 5CDLA 1QXZA 2GU7A 1XGSA 3PKCA 5JFRA 3PN9A 4IKUA 4U6CA 2BWVA 3CTZA 1XNZA 3D27A 1C22A 1WL6A 4U6JA 1PV9A 3Q6DA 2B3KA 1O0XA 4U73A 4A6VA 2EVOA 2BWYA 5FCHA 5CNXA 3S6BA 3MATA 2GU6A 4IDYA 4U6ZA 1B6AA 1KQ9A 2P99A 2B3HA 2V6CA 2GG2A 2BN7A 2BHBA 3OVKA 4RGZ1 3CB5A 2V3ZA 2P9AA 5CDEA 5CIKA 3TB5A 3L24A 3RVAA 1W2MA 3MX6A 5D6FA 5JHUA 4OOKA 4FLIA 1Y1NA 2GG0A 1WL9A 3BIPA 2B3LA 2BWTA 1YW7A 2GGBA 1QZYA 4IPAA 3FMRA 2Q96A 2P98A 1YW9A 3IU9A 2IW2A 4PV4A 2GZ5A 1WY2A 1KQ0A 4Z7MA 2GG5A 1WLRA 3BITA 1YJ3A 2ADUA 2EA2A 2MATA 5D6EA 4FLKA 2Q95A 1B59A 3IU8A 5FCFA 5JI6A 2EVCA 4HXXA 3TAVA 1R5HA 1XGOA 1C21A 1XGNA 2G6PA 5E5BA 3IU7A 1WN1A 1QXWA 2BHDA 4FO7A 2BWSA 1CHMA 2ZSGA 4MATA 4U70A 4FKCA 4U76A 1C23A 1C27A 3L7GA 1W7VA 2NQ6A 4FUKA 4U1BA 3FMQA 4U6WA 2Q92A 4ZNGA 1YW8A 2Q94A 2GG7A 5CDVA 3IG4A 4IKTA 4IKRA 3CB6A 1XGMA 5E2CA 1C24A 4FLJA 3PKAA 4EGEA 2GTXA 2OAZA 4PNCA 2BWUA 4ZWOA 5CE6A 4ZWPA 3I7MA 1JAWA 2DFIA 2V3YA 4ZWUA 4U69A 3RORA 2BWXA 4FO8A 4IKSA 2BHCA
chains in the Genus database with same CATH superfamily
2EA4A 4QR8A 4KM3A 1R5GA 2NQ7A 3OOOA 3QOCA 2GU5A 4RZZA 2GA2A 1M35A 2V3XA 1BN5A 4U75A 1R58A 3MR1A 3PEBA 2Q8KA 3PKBA 1QXYA 4IF7A 4RZYA 2HOWA 2GGCA 1A16A 5CLSA 4R60A 4S01A 2OKNA 1KP0A 2EVMA 2GG9A 2GG8A 3PKDA 2BHAA 4B28A 4S2RP 1WBQA 1N51A 1YVMA 4A6WA 3O5VA 3PKEA 2GG3A 2Q93A 4FLLA 4JUQA 4S00A 4IU6A 1WKMA 4S2TP 1MATA 4U6EA 4U71A 2BB7A 2GU4A 2BWWA 2BH3A 3IL0A 4IECA 3BIQA 1BOAA 3FM3A 5CDLA 1QXZA 2GU7A 1XGSA 3PKCA 5JFRA 3PN9A 4IKUA 4U6CA 2BWVA 3CTZA 1XNZA 3D27A 1C22A 1WL6A 4U6JA 1PV9A 3Q6DA 2B3KA 1O0XA 4U73A 4A6VA 2EVOA 2BWYA 5FCHA 5CNXA 3S6BA 3MATA 2GU6A 4IDYA 4U6ZA 1B6AA 1KQ9A 2P99A 2B3HA 2V6CA 2GG2A 2BN7A 2BHBA 3OVKA 4RGZ1 3CB5A 2V3ZA 2P9AA 5CDEA 5CIKA 3TB5A 3L24A 3RVAA 1W2MA 3MX6A 5D6FA 5JHUA 4OOKA 4FLIA 1Y1NA 2GG0A 1WL9A 3BIPA 2B3LA 2BWTA 1YW7A 2GGBA 1QZYA 4IPAA 3FMRA 2Q96A 2P98A 1YW9A 3IU9A 2IW2A 4PV4A 2GZ5A 1WY2A 1KQ0A 4Z7MA 2GG5A 1WLRA 3BITA 1YJ3A 2ADUA 2EA2A 2MATA 5D6EA 4FLKA 2Q95A 1B59A 3IU8A 5FCFA 5JI6A 2EVCA 4HXXA 3TAVA 1R5HA 1XGOA 1C21A 1XGNA 2G6PA 5E5BA 3IU7A 1WN1A 1QXWA 2BHDA 4FO7A 2BWSA 1CHMA 2ZSGA 4MATA 4U70A 4FKCA 4U76A 1C23A 1C27A 3L7GA 1W7VA 2NQ6A 4FUKA 4U1BA 3FMQA 4U6WA 2Q92A 4ZNGA 1YW8A 2Q94A 2GG7A 5CDVA 3IG4A 4IKTA 4IKRA 3CB6A 1XGMA 5E2CA 1C24A 4FLJA 3PKAA 4EGEA 2GTXA 2OAZA 4PNCA 2BWUA 4ZWOA 5CE6A 4ZWPA 3I7MA 1JAWA 2DFIA 2V3YA 4ZWUA 4U69A 3RORA 2BWXA 4FO8A 4IKSA 2BHCA
chains in the Genus database with same CATH topology
2EA4A 4QR8A 4KM3A 1R5GA 2NQ7A 3OOOA 3QOCA 2GU5A 4RZZA 2GA2A 1M35A 2V3XA 1BN5A 4U75A 1R58A 3MR1A 3PEBA 2Q8KA 3PKBA 1QXYA 4IF7A 4RZYA 2HOWA 2GGCA 1A16A 5CLSA 4R60A 4S01A 2OKNA 1KP0A 2EVMA 2GG9A 2GG8A 3PKDA 2BHAA 4B28A 4S2RP 1WBQA 1N51A 1YVMA 4A6WA 3O5VA 3PKEA 2GG3A 2Q93A 4FLLA 4JUQA 4S00A 4IU6A 1WKMA 4S2TP 1MATA 4U6EA 4U71A 2BB7A 2GU4A 2BWWA 2BH3A 3IL0A 4IECA 3BIQA 1BOAA 3FM3A 5CDLA 1QXZA 2GU7A 1XGSA 3PKCA 5JFRA 3PN9A 4IKUA 4U6CA 2BWVA 3CTZA 1XNZA 3D27A 1C22A 1WL6A 4U6JA 1PV9A 3Q6DA 2B3KA 1O0XA 4U73A 4A6VA 2EVOA 2BWYA 5FCHA 5CNXA 3S6BA 3MATA 2GU6A 4IDYA 4U6ZA 1B6AA 1KQ9A 2P99A 2B3HA 2V6CA 2GG2A 2BN7A 2BHBA 3OVKA 4RGZ1 3CB5A 2V3ZA 2P9AA 5CDEA 5CIKA 3TB5A 3L24A 3RVAA 1W2MA 3MX6A 5D6FA 5JHUA 4OOKA 4FLIA 1Y1NA 2GG0A 1WL9A 3BIPA 2B3LA 2BWTA 1YW7A 2GGBA 1QZYA 4IPAA 3FMRA 2Q96A 2P98A 1YW9A 3IU9A 2IW2A 4PV4A 2GZ5A 1WY2A 1KQ0A 4Z7MA 2GG5A 1WLRA 3BITA 1YJ3A 2ADUA 2EA2A 2MATA 5D6EA 4FLKA 2Q95A 1B59A 3IU8A 5FCFA 5JI6A 2EVCA 4HXXA 3TAVA 1R5HA 1XGOA 1C21A 1XGNA 2G6PA 5E5BA 3IU7A 1WN1A 1QXWA 2BHDA 4FO7A 2BWSA 1CHMA 2ZSGA 4MATA 4U70A 4FKCA 4U76A 1C23A 1C27A 3L7GA 1W7VA 2NQ6A 4FUKA 4U1BA 3FMQA 4U6WA 2Q92A 4ZNGA 1YW8A 2Q94A 2GG7A 5CDVA 3IG4A 4IKTA 4IKRA 3CB6A 1XGMA 5E2CA 1C24A 4FLJA 3PKAA 4EGEA 2GTXA 2OAZA 4PNCA 2BWUA 4ZWOA 5CE6A 4ZWPA 3I7MA 1JAWA 2DFIA 2V3YA 4ZWUA 4U69A 3RORA 2BWXA 4FO8A 4IKSA 2BHCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EA4 A;  4QR8 A;  4KM3 A;  1R5G A;  2NQ7 A;  3OOO A;  3QOC A;  2GU5 A;  4RZZ A;  2GA2 A;  1M35 A;  2V3X A;  1BN5 A;  4U75 A;  1R58 A;  3MR1 A;  3PEB A;  2Q8K A;  3PKB A;  1QXY A;  4IF7 A;  4RZY A;  2HOW A;  2GGC A;  1A16 A;  5CLS A;  4R60 A;  4S01 A;  2OKN A;  1KP0 A;  2EVM A;  2GG9 A;  2GG8 A;  3PKD A;  2BHA A;  4B28 A;  4S2R P;  1WBQ A;  1N51 A;  1YVM A;  4A6W A;  3O5V A;  3PKE A;  2GG3 A;  2Q93 A;  4FLL A;  4JUQ A;  4S00 A;  4IU6 A;  1WKM A;  4S2T P;  1MAT A;  4U6E A;  4U71 A;  2BB7 A;  2GU4 A;  2BWW A;  2BH3 A;  3IL0 A;  4IEC A;  3BIQ A;  1BOA A;  3FM3 A;  5CDL A;  1QXZ A;  2GU7 A;  1XGS A;  3PKC A;  5JFR A;  3PN9 A;  4IKU A;  4U6C A;  2BWV A;  3CTZ A;  1XNZ A;  3D27 A;  1C22 A;  1WL6 A;  4U6J A;  1PV9 A;  3Q6D A;  2B3K A;  1O0X A;  4U73 A;  4A6V A;  2EVO A;  2BWY A;  5FCH A;  5CNX A;  3S6B A;  3MAT A;  2GU6 A;  4IDY A;  4U6Z A;  1B6A A;  1KQ9 A;  2P99 A;  2B3H A;  2V6C A;  2GG2 A;  2BN7 A;  2BHB A;  3OVK A;  4RGZ 1;  3CB5 A;  2V3Z A;  2P9A A;  5CDE A;  5CIK A;  3TB5 A;  3L24 A;  3RVA A;  1W2M A;  3MX6 A;  5D6F A;  5JHU A;  4OOK A;  4FLI A;  1Y1N A;  2GG0 A;  1WL9 A;  3BIP A;  2B3L A;  2BWT A;  1YW7 A;  2GGB A;  1QZY A;  4IPA A;  3FMR A;  2Q96 A;  2P98 A;  1YW9 A;  3IU9 A;  2IW2 A;  4PV4 A;  2GZ5 A;  1WY2 A;  1KQ0 A;  4Z7M A;  2GG5 A;  1WLR A;  3BIT A;  1YJ3 A;  2ADU A;  2EA2 A;  2MAT A;  5D6E A;  4FLK A;  2Q95 A;  1B59 A;  3IU8 A;  5FCF A;  5JI6 A;  2EVC A;  4HXX A;  3TAV A;  1R5H A;  1XGO A;  1C21 A;  1XGN A;  2G6P A;  5E5B A;  3IU7 A;  1WN1 A;  1QXW A;  2BHD A;  4FO7 A;  2BWS A;  1CHM A;  2ZSG A;  4MAT A;  4U70 A;  4FKC A;  4U76 A;  1C23 A;  1C27 A;  3L7G A;  1W7V A;  2NQ6 A;  4FUK A;  4U1B A;  3FMQ A;  4U6W A;  2Q92 A;  4ZNG A;  1YW8 A;  2Q94 A;  2GG7 A;  5CDV A;  3IG4 A;  4IKT A;  4IKR A;  3CB6 A;  1XGM A;  5E2C A;  1C24 A;  4FLJ A;  3PKA A;  4EGE A;  2GTX A;  2OAZ A;  4PNC A;  2BWU A;  4ZWO A;  5CE6 A;  4ZWP A;  3I7M A;  1JAW A;  2DFI A;  2V3Y A;  4ZWU A;  4U69 A;  3ROR A;  2BWX A;  4FO8 A;  4IKS A;  2BHC A; 
#chains in the Genus database with same CATH topology
 2EA4 A;  4QR8 A;  4KM3 A;  1R5G A;  2NQ7 A;  3OOO A;  3QOC A;  2GU5 A;  4RZZ A;  2GA2 A;  1M35 A;  2V3X A;  1BN5 A;  4U75 A;  1R58 A;  3MR1 A;  3PEB A;  2Q8K A;  3PKB A;  1QXY A;  4IF7 A;  4RZY A;  2HOW A;  2GGC A;  1A16 A;  5CLS A;  4R60 A;  4S01 A;  2OKN A;  1KP0 A;  2EVM A;  2GG9 A;  2GG8 A;  3PKD A;  2BHA A;  4B28 A;  4S2R P;  1WBQ A;  1N51 A;  1YVM A;  4A6W A;  3O5V A;  3PKE A;  2GG3 A;  2Q93 A;  4FLL A;  4JUQ A;  4S00 A;  4IU6 A;  1WKM A;  4S2T P;  1MAT A;  4U6E A;  4U71 A;  2BB7 A;  2GU4 A;  2BWW A;  2BH3 A;  3IL0 A;  4IEC A;  3BIQ A;  1BOA A;  3FM3 A;  5CDL A;  1QXZ A;  2GU7 A;  1XGS A;  3PKC A;  5JFR A;  3PN9 A;  4IKU A;  4U6C A;  2BWV A;  3CTZ A;  1XNZ A;  3D27 A;  1C22 A;  1WL6 A;  4U6J A;  1PV9 A;  3Q6D A;  2B3K A;  1O0X A;  4U73 A;  4A6V A;  2EVO A;  2BWY A;  5FCH A;  5CNX A;  3S6B A;  3MAT A;  2GU6 A;  4IDY A;  4U6Z A;  1B6A A;  1KQ9 A;  2P99 A;  2B3H A;  2V6C A;  2GG2 A;  2BN7 A;  2BHB A;  3OVK A;  4RGZ 1;  3CB5 A;  2V3Z A;  2P9A A;  5CDE A;  5CIK A;  3TB5 A;  3L24 A;  3RVA A;  1W2M A;  3MX6 A;  5D6F A;  5JHU A;  4OOK A;  4FLI A;  1Y1N A;  2GG0 A;  1WL9 A;  3BIP A;  2B3L A;  2BWT A;  1YW7 A;  2GGB A;  1QZY A;  4IPA A;  3FMR A;  2Q96 A;  2P98 A;  1YW9 A;  3IU9 A;  2IW2 A;  4PV4 A;  2GZ5 A;  1WY2 A;  1KQ0 A;  4Z7M A;  2GG5 A;  1WLR A;  3BIT A;  1YJ3 A;  2ADU A;  2EA2 A;  2MAT A;  5D6E A;  4FLK A;  2Q95 A;  1B59 A;  3IU8 A;  5FCF A;  5JI6 A;  2EVC A;  4HXX A;  3TAV A;  1R5H A;  1XGO A;  1C21 A;  1XGN A;  2G6P A;  5E5B A;  3IU7 A;  1WN1 A;  1QXW A;  2BHD A;  4FO7 A;  2BWS A;  1CHM A;  2ZSG A;  4MAT A;  4U70 A;  4FKC A;  4U76 A;  1C23 A;  1C27 A;  3L7G A;  1W7V A;  2NQ6 A;  4FUK A;  4U1B A;  3FMQ A;  4U6W A;  2Q92 A;  4ZNG A;  1YW8 A;  2Q94 A;  2GG7 A;  5CDV A;  3IG4 A;  4IKT A;  4IKR A;  3CB6 A;  1XGM A;  5E2C A;  1C24 A;  4FLJ A;  3PKA A;  4EGE A;  2GTX A;  2OAZ A;  4PNC A;  2BWU A;  4ZWO A;  5CE6 A;  4ZWP A;  3I7M A;  1JAW A;  2DFI A;  2V3Y A;  4ZWU A;  4U69 A;  3ROR A;  2BWX A;  4FO8 A;  4IKS A;  2BHC A; 
#chains in the Genus database with same CATH homology
 2EA4 A;  4QR8 A;  4KM3 A;  1R5G A;  2NQ7 A;  3OOO A;  3QOC A;  2GU5 A;  4RZZ A;  2GA2 A;  1M35 A;  2V3X A;  1BN5 A;  4U75 A;  1R58 A;  3MR1 A;  3PEB A;  2Q8K A;  3PKB A;  1QXY A;  4IF7 A;  4RZY A;  2HOW A;  2GGC A;  1A16 A;  5CLS A;  4R60 A;  4S01 A;  2OKN A;  1KP0 A;  2EVM A;  2GG9 A;  2GG8 A;  3PKD A;  2BHA A;  4B28 A;  4S2R P;  1WBQ A;  1N51 A;  1YVM A;  4A6W A;  3O5V A;  3PKE A;  2GG3 A;  2Q93 A;  4FLL A;  4JUQ A;  4S00 A;  4IU6 A;  1WKM A;  4S2T P;  1MAT A;  4U6E A;  4U71 A;  2BB7 A;  2GU4 A;  2BWW A;  2BH3 A;  3IL0 A;  4IEC A;  3BIQ A;  1BOA A;  3FM3 A;  5CDL A;  1QXZ A;  2GU7 A;  1XGS A;  3PKC A;  5JFR A;  3PN9 A;  4IKU A;  4U6C A;  2BWV A;  3CTZ A;  1XNZ A;  3D27 A;  1C22 A;  1WL6 A;  4U6J A;  1PV9 A;  3Q6D A;  2B3K A;  1O0X A;  4U73 A;  4A6V A;  2EVO A;  2BWY A;  5FCH A;  5CNX A;  3S6B A;  3MAT A;  2GU6 A;  4IDY A;  4U6Z A;  1B6A A;  1KQ9 A;  2P99 A;  2B3H A;  2V6C A;  2GG2 A;  2BN7 A;  2BHB A;  3OVK A;  4RGZ 1;  3CB5 A;  2V3Z A;  2P9A A;  5CDE A;  5CIK A;  3TB5 A;  3L24 A;  3RVA A;  1W2M A;  3MX6 A;  5D6F A;  5JHU A;  4OOK A;  4FLI A;  1Y1N A;  2GG0 A;  1WL9 A;  3BIP A;  2B3L A;  2BWT A;  1YW7 A;  2GGB A;  1QZY A;  4IPA A;  3FMR A;  2Q96 A;  2P98 A;  1YW9 A;  3IU9 A;  2IW2 A;  4PV4 A;  2GZ5 A;  1WY2 A;  1KQ0 A;  4Z7M A;  2GG5 A;  1WLR A;  3BIT A;  1YJ3 A;  2ADU A;  2EA2 A;  2MAT A;  5D6E A;  4FLK A;  2Q95 A;  1B59 A;  3IU8 A;  5FCF A;  5JI6 A;  2EVC A;  4HXX A;  3TAV A;  1R5H A;  1XGO A;  1C21 A;  1XGN A;  2G6P A;  5E5B A;  3IU7 A;  1WN1 A;  1QXW A;  2BHD A;  4FO7 A;  2BWS A;  1CHM A;  2ZSG A;  4MAT A;  4U70 A;  4FKC A;  4U76 A;  1C23 A;  1C27 A;  3L7G A;  1W7V A;  2NQ6 A;  4FUK A;  4U1B A;  3FMQ A;  4U6W A;  2Q92 A;  4ZNG A;  1YW8 A;  2Q94 A;  2GG7 A;  5CDV A;  3IG4 A;  4IKT A;  4IKR A;  3CB6 A;  1XGM A;  5E2C A;  1C24 A;  4FLJ A;  3PKA A;  4EGE A;  2GTX A;  2OAZ A;  4PNC A;  2BWU A;  4ZWO A;  5CE6 A;  4ZWP A;  3I7M A;  1JAW A;  2DFI A;  2V3Y A;  4ZWU A;  4U69 A;  3ROR A;  2BWX A;  4FO8 A;  4IKS A;  2BHC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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#similar chains in the pdb database (?% sequence similarity)
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