1WY2A

Crystal structure of the prolidase from pyrococcus horikoshii ot3
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
351
structure length
351
Chain Sequence
MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
publication title Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Hydrolase
total genus 126
structure length 351
sequence length 351
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2005-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wy2A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wy2A02
2ZSGA 1WY2A 3RVAA 2Q8KA 2BHBA 4QR8A 2GA2A 2BWVA 2Q95A 2BH3A 2GU6A 1R5HA 2GG2A 4IF7A 1YJ3A 4U6CA 2B3HA 3PN9A 5JFRA 4RZZA 2GGCA 4U69A 4A6VA 2GGBA 4FLIA 4IKSA 2P99A 1QXYA 5CIKA 3BIPA 1C22A 3IU7A 2BWSA 5CDVA 3PKEA 1QXWA 2OKNA 1WBQA 2BHAA 2NQ7A 2BB7A 1A16A 1XNZA 3BITA 4EGEA 1QXZA 1XGNA 2GG0A 3OOOA 4MATA 4S2TP 3FMRA 4U70A 5JHUA 1WL6A 4FUKA 3IG4A 3QOCA 2P98A 4PNCA 2DFIA 3IU8A 2GG9A 5D6FA 4IKTA 3PKDA 5CDLA 1KQ9A 4IDYA 1PV9A 2BHDA 2Q94A 2EA2A 2NQ6A 4OOKA 4U71A 4RZYA 4FKCA 2B3KA 2GG3A 3MR1A 2BWWA 3PKCA 1MATA 1Y1NA 4IPAA 1BOAA 5CLSA 4A6WA 4FO8A 1XGMA 4U1BA 1C27A 2IW2A 4S2RP 1YW9A 4FO7A 1CHMA 2V3XA 5CE6A 2Q93A 4PV4A 2BWYA 4IKRA 4U6EA 5CNXA 1YW7A 4HXXA 1C21A 2BHCA 2OAZA 3IU9A 4IU6A 1QZYA 2Q96A 3CB5A 1WKMA 4U73A 2GZ5A 4IECA 2ADUA 5E5BA 4U6WA 3IL0A 3D27A 5FCFA 2G6PA 4IKUA 1R58A 3O5VA 2GU5A 4FLJA 2MATA 2HOWA 4B28A 1BN5A 2EVMA 3Q6DA 4ZWPA 4ZWUA 4ZWOA 3TB5A 4FLLA 4Z7MA 3PEBA 2V3ZA 3BIQA 3OVKA 5D6EA 2BN7A 4RGZ1 1YW8A 1XGOA 3I7MA 1O0XA 4U76A 1YVMA 1W2MA 5JI6A 1W7VA 2GU7A 3L24A 5FCHA 3S6BA 2EVOA 3MX6A 2P9AA 3RORA 1M35A 1B59A 1C23A 2GG8A 4FLKA 3L7GA 2GTXA 1XGSA 2Q92A 1WL9A 4JUQA 4S01A 2EVCA 1N51A 1WLRA 5CDEA 1JAWA 3CB6A 3CTZA 5E2CA 2GG5A 3FMQA 3MATA 4U6JA 4U75A 3PKBA 1KQ0A 3FM3A 4ZNGA 2BWTA 2EA4A 2GU4A 3PKAA 4KM3A 3TAVA 2BWXA 1C24A 1KP0A 4U6ZA 1R5GA 1B6AA 1WN1A 2B3LA 2V6CA 2GG7A 4S00A 2BWUA 2V3YA 4R60A
chains in the Genus database with same CATH superfamily
2ZSGA 1WY2A 3RVAA 2Q8KA 2BHBA 4QR8A 2GA2A 2BWVA 2Q95A 2BH3A 2GU6A 1R5HA 2GG2A 4IF7A 1YJ3A 4U6CA 2B3HA 3PN9A 5JFRA 4RZZA 2GGCA 4U69A 4A6VA 2GGBA 4FLIA 4IKSA 2P99A 1QXYA 5CIKA 3BIPA 1C22A 3IU7A 2BWSA 5CDVA 3PKEA 1QXWA 2OKNA 1WBQA 2BHAA 2NQ7A 2BB7A 1A16A 1XNZA 3BITA 4EGEA 1QXZA 1XGNA 2GG0A 3OOOA 4MATA 4S2TP 3FMRA 4U70A 5JHUA 1WL6A 4FUKA 3IG4A 3QOCA 2P98A 4PNCA 2DFIA 3IU8A 2GG9A 5D6FA 4IKTA 3PKDA 5CDLA 1KQ9A 4IDYA 1PV9A 2BHDA 2Q94A 2EA2A 2NQ6A 4OOKA 4U71A 4RZYA 4FKCA 2B3KA 2GG3A 3MR1A 2BWWA 3PKCA 1MATA 1Y1NA 4IPAA 1BOAA 5CLSA 4A6WA 4FO8A 1XGMA 4U1BA 1C27A 2IW2A 4S2RP 1YW9A 4FO7A 1CHMA 2V3XA 5CE6A 2Q93A 4PV4A 2BWYA 4IKRA 4U6EA 5CNXA 1YW7A 4HXXA 1C21A 2BHCA 2OAZA 3IU9A 4IU6A 1QZYA 2Q96A 3CB5A 1WKMA 4U73A 2GZ5A 4IECA 2ADUA 5E5BA 4U6WA 3IL0A 3D27A 5FCFA 2G6PA 4IKUA 1R58A 3O5VA 2GU5A 4FLJA 2MATA 2HOWA 4B28A 1BN5A 2EVMA 3Q6DA 4ZWPA 4ZWUA 4ZWOA 3TB5A 4FLLA 4Z7MA 3PEBA 2V3ZA 3BIQA 3OVKA 5D6EA 2BN7A 4RGZ1 1YW8A 1XGOA 3I7MA 1O0XA 4U76A 1YVMA 1W2MA 5JI6A 1W7VA 2GU7A 3L24A 5FCHA 3S6BA 2EVOA 3MX6A 2P9AA 3RORA 1M35A 1B59A 1C23A 2GG8A 4FLKA 3L7GA 2GTXA 1XGSA 2Q92A 1WL9A 4JUQA 4S01A 2EVCA 1N51A 1WLRA 5CDEA 1JAWA 3CB6A 3CTZA 5E2CA 2GG5A 3FMQA 3MATA 4U6JA 4U75A 3PKBA 1KQ0A 3FM3A 4ZNGA 2BWTA 2EA4A 2GU4A 3PKAA 4KM3A 3TAVA 2BWXA 1C24A 1KP0A 4U6ZA 1R5GA 1B6AA 1WN1A 2B3LA 2V6CA 2GG7A 4S00A 2BWUA 2V3YA 4R60A
chains in the Genus database with same CATH topology
2ZSGA 1WY2A 3RVAA 2Q8KA 2BHBA 4QR8A 2GA2A 2BWVA 2Q95A 2BH3A 2GU6A 1R5HA 2GG2A 4IF7A 1YJ3A 4U6CA 2B3HA 3PN9A 5JFRA 4RZZA 2GGCA 4U69A 4A6VA 2GGBA 4FLIA 4IKSA 2P99A 1QXYA 5CIKA 3BIPA 1C22A 3IU7A 2BWSA 5CDVA 3PKEA 1QXWA 2OKNA 1WBQA 2BHAA 2NQ7A 2BB7A 1A16A 1XNZA 3BITA 4EGEA 1QXZA 1XGNA 2GG0A 3OOOA 4MATA 4S2TP 3FMRA 4U70A 5JHUA 1WL6A 4FUKA 3IG4A 3QOCA 2P98A 4PNCA 2DFIA 3IU8A 2GG9A 5D6FA 4IKTA 3PKDA 5CDLA 1KQ9A 4IDYA 1PV9A 2BHDA 2Q94A 2EA2A 2NQ6A 4OOKA 4U71A 4RZYA 4FKCA 2B3KA 2GG3A 3MR1A 2BWWA 3PKCA 1MATA 1Y1NA 4IPAA 1BOAA 5CLSA 4A6WA 4FO8A 1XGMA 4U1BA 1C27A 2IW2A 4S2RP 1YW9A 4FO7A 1CHMA 2V3XA 5CE6A 2Q93A 4PV4A 2BWYA 4IKRA 4U6EA 5CNXA 1YW7A 4HXXA 1C21A 2BHCA 2OAZA 3IU9A 4IU6A 1QZYA 2Q96A 3CB5A 1WKMA 4U73A 2GZ5A 4IECA 2ADUA 5E5BA 4U6WA 3IL0A 3D27A 5FCFA 2G6PA 4IKUA 1R58A 3O5VA 2GU5A 4FLJA 2MATA 2HOWA 4B28A 1BN5A 2EVMA 3Q6DA 4ZWPA 4ZWUA 4ZWOA 3TB5A 4FLLA 4Z7MA 3PEBA 2V3ZA 3BIQA 3OVKA 5D6EA 2BN7A 4RGZ1 1YW8A 1XGOA 3I7MA 1O0XA 4U76A 1YVMA 1W2MA 5JI6A 1W7VA 2GU7A 3L24A 5FCHA 3S6BA 2EVOA 3MX6A 2P9AA 3RORA 1M35A 1B59A 1C23A 2GG8A 4FLKA 3L7GA 2GTXA 1XGSA 2Q92A 1WL9A 4JUQA 4S01A 2EVCA 1N51A 1WLRA 5CDEA 1JAWA 3CB6A 3CTZA 5E2CA 2GG5A 3FMQA 3MATA 4U6JA 4U75A 3PKBA 1KQ0A 3FM3A 4ZNGA 2BWTA 2EA4A 2GU4A 3PKAA 4KM3A 3TAVA 2BWXA 1C24A 1KP0A 4U6ZA 1R5GA 1B6AA 1WN1A 2B3LA 2V6CA 2GG7A 4S00A 2BWUA 2V3YA 4R60A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2ZSG A;  1WY2 A;  3RVA A;  2Q8K A;  2BHB A;  4QR8 A;  2GA2 A;  2BWV A;  2Q95 A;  2BH3 A;  2GU6 A;  1R5H A;  2GG2 A;  4IF7 A;  1YJ3 A;  4U6C A;  2B3H A;  3PN9 A;  5JFR A;  4RZZ A;  2GGC A;  4U69 A;  4A6V A;  2GGB A;  4FLI A;  4IKS A;  2P99 A;  1QXY A;  5CIK A;  3BIP A;  1C22 A;  3IU7 A;  2BWS A;  5CDV A;  3PKE A;  1QXW A;  2OKN A;  1WBQ A;  2BHA A;  2NQ7 A;  2BB7 A;  1A16 A;  1XNZ A;  3BIT A;  4EGE A;  1QXZ A;  1XGN A;  2GG0 A;  3OOO A;  4MAT A;  4S2T P;  3FMR A;  4U70 A;  5JHU A;  1WL6 A;  4FUK A;  3IG4 A;  3QOC A;  2P98 A;  4PNC A;  2DFI A;  3IU8 A;  2GG9 A;  5D6F A;  4IKT A;  3PKD A;  5CDL A;  1KQ9 A;  4IDY A;  1PV9 A;  2BHD A;  2Q94 A;  2EA2 A;  2NQ6 A;  4OOK A;  4U71 A;  4RZY A;  4FKC A;  2B3K A;  2GG3 A;  3MR1 A;  2BWW A;  3PKC A;  1MAT A;  1Y1N A;  4IPA A;  1BOA A;  5CLS A;  4A6W A;  4FO8 A;  1XGM A;  4U1B A;  1C27 A;  2IW2 A;  4S2R P;  1YW9 A;  4FO7 A;  1CHM A;  2V3X A;  5CE6 A;  2Q93 A;  4PV4 A;  2BWY A;  4IKR A;  4U6E A;  5CNX A;  1YW7 A;  4HXX A;  1C21 A;  2BHC A;  2OAZ A;  3IU9 A;  4IU6 A;  1QZY A;  2Q96 A;  3CB5 A;  1WKM A;  4U73 A;  2GZ5 A;  4IEC A;  2ADU A;  5E5B A;  4U6W A;  3IL0 A;  3D27 A;  5FCF A;  2G6P A;  4IKU A;  1R58 A;  3O5V A;  2GU5 A;  4FLJ A;  2MAT A;  2HOW A;  4B28 A;  1BN5 A;  2EVM A;  3Q6D A;  4ZWP A;  4ZWU A;  4ZWO A;  3TB5 A;  4FLL A;  4Z7M A;  3PEB A;  2V3Z A;  3BIQ A;  3OVK A;  5D6E A;  2BN7 A;  4RGZ 1;  1YW8 A;  1XGO A;  3I7M A;  1O0X A;  4U76 A;  1YVM A;  1W2M A;  5JI6 A;  1W7V A;  2GU7 A;  3L24 A;  5FCH A;  3S6B A;  2EVO A;  3MX6 A;  2P9A A;  3ROR A;  1M35 A;  1B59 A;  1C23 A;  2GG8 A;  4FLK A;  3L7G A;  2GTX A;  1XGS A;  2Q92 A;  1WL9 A;  4JUQ A;  4S01 A;  2EVC A;  1N51 A;  1WLR A;  5CDE A;  1JAW A;  3CB6 A;  3CTZ A;  5E2C A;  2GG5 A;  3FMQ A;  3MAT A;  4U6J A;  4U75 A;  3PKB A;  1KQ0 A;  3FM3 A;  4ZNG A;  2BWT A;  2EA4 A;  2GU4 A;  3PKA A;  4KM3 A;  3TAV A;  2BWX A;  1C24 A;  1KP0 A;  4U6Z A;  1R5G A;  1B6A A;  1WN1 A;  2B3L A;  2V6C A;  2GG7 A;  4S00 A;  2BWU A;  2V3Y A;  4R60 A; 
#chains in the Genus database with same CATH topology
 2ZSG A;  1WY2 A;  3RVA A;  2Q8K A;  2BHB A;  4QR8 A;  2GA2 A;  2BWV A;  2Q95 A;  2BH3 A;  2GU6 A;  1R5H A;  2GG2 A;  4IF7 A;  1YJ3 A;  4U6C A;  2B3H A;  3PN9 A;  5JFR A;  4RZZ A;  2GGC A;  4U69 A;  4A6V A;  2GGB A;  4FLI A;  4IKS A;  2P99 A;  1QXY A;  5CIK A;  3BIP A;  1C22 A;  3IU7 A;  2BWS A;  5CDV A;  3PKE A;  1QXW A;  2OKN A;  1WBQ A;  2BHA A;  2NQ7 A;  2BB7 A;  1A16 A;  1XNZ A;  3BIT A;  4EGE A;  1QXZ A;  1XGN A;  2GG0 A;  3OOO A;  4MAT A;  4S2T P;  3FMR A;  4U70 A;  5JHU A;  1WL6 A;  4FUK A;  3IG4 A;  3QOC A;  2P98 A;  4PNC A;  2DFI A;  3IU8 A;  2GG9 A;  5D6F A;  4IKT A;  3PKD A;  5CDL A;  1KQ9 A;  4IDY A;  1PV9 A;  2BHD A;  2Q94 A;  2EA2 A;  2NQ6 A;  4OOK A;  4U71 A;  4RZY A;  4FKC A;  2B3K A;  2GG3 A;  3MR1 A;  2BWW A;  3PKC A;  1MAT A;  1Y1N A;  4IPA A;  1BOA A;  5CLS A;  4A6W A;  4FO8 A;  1XGM A;  4U1B A;  1C27 A;  2IW2 A;  4S2R P;  1YW9 A;  4FO7 A;  1CHM A;  2V3X A;  5CE6 A;  2Q93 A;  4PV4 A;  2BWY A;  4IKR A;  4U6E A;  5CNX A;  1YW7 A;  4HXX A;  1C21 A;  2BHC A;  2OAZ A;  3IU9 A;  4IU6 A;  1QZY A;  2Q96 A;  3CB5 A;  1WKM A;  4U73 A;  2GZ5 A;  4IEC A;  2ADU A;  5E5B A;  4U6W A;  3IL0 A;  3D27 A;  5FCF A;  2G6P A;  4IKU A;  1R58 A;  3O5V A;  2GU5 A;  4FLJ A;  2MAT A;  2HOW A;  4B28 A;  1BN5 A;  2EVM A;  3Q6D A;  4ZWP A;  4ZWU A;  4ZWO A;  3TB5 A;  4FLL A;  4Z7M A;  3PEB A;  2V3Z A;  3BIQ A;  3OVK A;  5D6E A;  2BN7 A;  4RGZ 1;  1YW8 A;  1XGO A;  3I7M A;  1O0X A;  4U76 A;  1YVM A;  1W2M A;  5JI6 A;  1W7V A;  2GU7 A;  3L24 A;  5FCH A;  3S6B A;  2EVO A;  3MX6 A;  2P9A A;  3ROR A;  1M35 A;  1B59 A;  1C23 A;  2GG8 A;  4FLK A;  3L7G A;  2GTX A;  1XGS A;  2Q92 A;  1WL9 A;  4JUQ A;  4S01 A;  2EVC A;  1N51 A;  1WLR A;  5CDE A;  1JAW A;  3CB6 A;  3CTZ A;  5E2C A;  2GG5 A;  3FMQ A;  3MAT A;  4U6J A;  4U75 A;  3PKB A;  1KQ0 A;  3FM3 A;  4ZNG A;  2BWT A;  2EA4 A;  2GU4 A;  3PKA A;  4KM3 A;  3TAV A;  2BWX A;  1C24 A;  1KP0 A;  4U6Z A;  1R5G A;  1B6A A;  1WN1 A;  2B3L A;  2V6C A;  2GG7 A;  4S00 A;  2BWU A;  2V3Y A;  4R60 A; 
#chains in the Genus database with same CATH homology
 2ZSG A;  1WY2 A;  3RVA A;  2Q8K A;  2BHB A;  4QR8 A;  2GA2 A;  2BWV A;  2Q95 A;  2BH3 A;  2GU6 A;  1R5H A;  2GG2 A;  4IF7 A;  1YJ3 A;  4U6C A;  2B3H A;  3PN9 A;  5JFR A;  4RZZ A;  2GGC A;  4U69 A;  4A6V A;  2GGB A;  4FLI A;  4IKS A;  2P99 A;  1QXY A;  5CIK A;  3BIP A;  1C22 A;  3IU7 A;  2BWS A;  5CDV A;  3PKE A;  1QXW A;  2OKN A;  1WBQ A;  2BHA A;  2NQ7 A;  2BB7 A;  1A16 A;  1XNZ A;  3BIT A;  4EGE A;  1QXZ A;  1XGN A;  2GG0 A;  3OOO A;  4MAT A;  4S2T P;  3FMR A;  4U70 A;  5JHU A;  1WL6 A;  4FUK A;  3IG4 A;  3QOC A;  2P98 A;  4PNC A;  2DFI A;  3IU8 A;  2GG9 A;  5D6F A;  4IKT A;  3PKD A;  5CDL A;  1KQ9 A;  4IDY A;  1PV9 A;  2BHD A;  2Q94 A;  2EA2 A;  2NQ6 A;  4OOK A;  4U71 A;  4RZY A;  4FKC A;  2B3K A;  2GG3 A;  3MR1 A;  2BWW A;  3PKC A;  1MAT A;  1Y1N A;  4IPA A;  1BOA A;  5CLS A;  4A6W A;  4FO8 A;  1XGM A;  4U1B A;  1C27 A;  2IW2 A;  4S2R P;  1YW9 A;  4FO7 A;  1CHM A;  2V3X A;  5CE6 A;  2Q93 A;  4PV4 A;  2BWY A;  4IKR A;  4U6E A;  5CNX A;  1YW7 A;  4HXX A;  1C21 A;  2BHC A;  2OAZ A;  3IU9 A;  4IU6 A;  1QZY A;  2Q96 A;  3CB5 A;  1WKM A;  4U73 A;  2GZ5 A;  4IEC A;  2ADU A;  5E5B A;  4U6W A;  3IL0 A;  3D27 A;  5FCF A;  2G6P A;  4IKU A;  1R58 A;  3O5V A;  2GU5 A;  4FLJ A;  2MAT A;  2HOW A;  4B28 A;  1BN5 A;  2EVM A;  3Q6D A;  4ZWP A;  4ZWU A;  4ZWO A;  3TB5 A;  4FLL A;  4Z7M A;  3PEB A;  2V3Z A;  3BIQ A;  3OVK A;  5D6E A;  2BN7 A;  4RGZ 1;  1YW8 A;  1XGO A;  3I7M A;  1O0X A;  4U76 A;  1YVM A;  1W2M A;  5JI6 A;  1W7V A;  2GU7 A;  3L24 A;  5FCH A;  3S6B A;  2EVO A;  3MX6 A;  2P9A A;  3ROR A;  1M35 A;  1B59 A;  1C23 A;  2GG8 A;  4FLK A;  3L7G A;  2GTX A;  1XGS A;  2Q92 A;  1WL9 A;  4JUQ A;  4S01 A;  2EVC A;  1N51 A;  1WLR A;  5CDE A;  1JAW A;  3CB6 A;  3CTZ A;  5E2C A;  2GG5 A;  3FMQ A;  3MAT A;  4U6J A;  4U75 A;  3PKB A;  1KQ0 A;  3FM3 A;  4ZNG A;  2BWT A;  2EA4 A;  2GU4 A;  3PKA A;  4KM3 A;  3TAV A;  2BWX A;  1C24 A;  1KP0 A;  4U6Z A;  1R5G A;  1B6A A;  1WN1 A;  2B3L A;  2V6C A;  2GG7 A;  4S00 A;  2BWU A;  2V3Y A;  4R60 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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