1WY2A

Crystal structure of the prolidase from pyrococcus horikoshii ot3
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
351
structure length
351
Chain Sequence
MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
source organism Pyrococcus horikoshii
publication title Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
rcsb
molecule keywords Xaa-Pro dipeptidase
total genus 126
structure length 351
sequence length 351
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2005-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wy2A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wy2A02
3CB5A 1KQ0A 3RVAA 1C22A 4HXXA 3L7GA 4EGEA 1C21A 3O5VA 1WL9A 2BWUA 2GA2A 4U6JA 4A6WA 4IECA 3CB6A 2B3LA 2BN7A 4S00A 1KQ9A 4Z7MA 2Q92A 4IPAA 5CIKA 2GG2A 1WKMA 3QOCA 3PKEA 4ZWPA 4PV4A 1B59A 2B3KA 4U71A 4U6EA 1KP0A 5CDEA 1O0XA 4S2TP 2GG0A 4OOKA 5CDLA 2BWSA 2GU4A 4IU6A 2EVOA 1WN1A 4RGZ1 1QXYA 2GU5A 2BHBA 3IL0A 3D27A 2GG9A 1B6AA 4IKSA 2P99A 4PNCA 5CDVA 1YJ3A 2G6PA 4FLIA 2P9AA 3PN9A 1BOAA 2V6CA 4IF7A 1WLRA 3OOOA 2EA2A 3PKDA 5CE6A 5E2CA 4U6ZA 4ZWOA 5CNXA 4B28A 4JUQA 2GG8A 5FCHA 2GG5A 2IW2A 3PEBA 1R5GA 4U69A 1YVMA 3OVKA 2OAZA 2BWWA 4U6CA 5JHUA 5JI6A 3PKCA 5CLSA 1PV9A 3MX6A 1M35A 5E5BA 2P98A 5JFRA 4U1BA 4RZZA 3TB5A 3FM3A 1WBQA 2Q94A 1XGSA 3MATA 2V3ZA 3BIPA 2GU7A 3FMQA 4MATA 3IU9A 1R5HA 4U70A 4U6WA 2Q95A 4RZYA 4FO8A 3CTZA 3I7MA 2HOWA 4R60A 2B3HA 2GGCA 2BH3A 2BWVA 2MATA 4ZWUA 2BWTA 2EVMA 1R58A 1C23A 1YW7A 4U75A 2GG7A 1JAWA 2GU6A 4IDYA 1Y1NA 4FO7A 4S2RP 2Q8KA 1QZYA 1YW8A 2BHCA 2BWXA 5FCFA 3IU7A 4FLLA 4IKUA 1BN5A 3FMRA 4QR8A 1QXWA 1YW9A 2NQ6A 4FLKA 3TAVA 4IKRA 3Q6DA 2Q96A 2GG3A 4IKTA 3IG4A 5D6FA 1A16A 2EA4A 3BITA 3L24A 1W2MA 1WL6A 2BHDA 1MATA 2GZ5A 3MR1A 1XGMA 4KM3A 2EVCA 4U76A 3S6BA 1N51A 2DFIA 2ZSGA 1XGNA 2OKNA 4U73A 3PKAA 4FKCA 1QXZA 2V3XA 1WY2A 1W7VA 3IU8A 2GTXA 4FUKA 2Q93A 4S01A 2BHAA 2GGBA 4A6VA 1CHMA 2NQ7A 3BIQA 2V3YA 3PKBA 1XGOA 3RORA 2ADUA 4FLJA 4ZNGA 1C27A 1C24A 5D6EA 2BB7A 2BWYA 1XNZA
chains in the Genus database with same CATH superfamily
3CB5A 1KQ0A 3RVAA 1C22A 4HXXA 3L7GA 4EGEA 1C21A 3O5VA 1WL9A 2BWUA 2GA2A 4U6JA 4A6WA 4IECA 3CB6A 2B3LA 2BN7A 4S00A 1KQ9A 4Z7MA 2Q92A 4IPAA 5CIKA 2GG2A 1WKMA 3QOCA 3PKEA 4ZWPA 4PV4A 1B59A 2B3KA 4U71A 4U6EA 1KP0A 5CDEA 1O0XA 4S2TP 2GG0A 4OOKA 5CDLA 2BWSA 2GU4A 4IU6A 2EVOA 1WN1A 4RGZ1 1QXYA 2GU5A 2BHBA 3IL0A 3D27A 2GG9A 1B6AA 4IKSA 2P99A 4PNCA 5CDVA 1YJ3A 2G6PA 4FLIA 2P9AA 3PN9A 1BOAA 2V6CA 4IF7A 1WLRA 3OOOA 2EA2A 3PKDA 5CE6A 5E2CA 4U6ZA 4ZWOA 5CNXA 4B28A 4JUQA 2GG8A 5FCHA 2GG5A 2IW2A 3PEBA 1R5GA 4U69A 1YVMA 3OVKA 2OAZA 2BWWA 4U6CA 5JHUA 5JI6A 3PKCA 5CLSA 1PV9A 3MX6A 1M35A 5E5BA 2P98A 5JFRA 4U1BA 4RZZA 3TB5A 3FM3A 1WBQA 2Q94A 1XGSA 3MATA 2V3ZA 3BIPA 2GU7A 3FMQA 4MATA 3IU9A 1R5HA 4U70A 4U6WA 2Q95A 4RZYA 4FO8A 3CTZA 3I7MA 2HOWA 4R60A 2B3HA 2GGCA 2BH3A 2BWVA 2MATA 4ZWUA 2BWTA 2EVMA 1R58A 1C23A 1YW7A 4U75A 2GG7A 1JAWA 2GU6A 4IDYA 1Y1NA 4FO7A 4S2RP 2Q8KA 1QZYA 1YW8A 2BHCA 2BWXA 5FCFA 3IU7A 4FLLA 4IKUA 1BN5A 3FMRA 4QR8A 1QXWA 1YW9A 2NQ6A 4FLKA 3TAVA 4IKRA 3Q6DA 2Q96A 2GG3A 4IKTA 3IG4A 5D6FA 1A16A 2EA4A 3BITA 3L24A 1W2MA 1WL6A 2BHDA 1MATA 2GZ5A 3MR1A 1XGMA 4KM3A 2EVCA 4U76A 3S6BA 1N51A 2DFIA 2ZSGA 1XGNA 2OKNA 4U73A 3PKAA 4FKCA 1QXZA 2V3XA 1WY2A 1W7VA 3IU8A 2GTXA 4FUKA 2Q93A 4S01A 2BHAA 2GGBA 4A6VA 1CHMA 2NQ7A 3BIQA 2V3YA 3PKBA 1XGOA 3RORA 2ADUA 4FLJA 4ZNGA 1C27A 1C24A 5D6EA 2BB7A 2BWYA 1XNZA
chains in the Genus database with same CATH topology
3CB5A 1KQ0A 3RVAA 1C22A 4HXXA 3L7GA 4EGEA 1C21A 3O5VA 1WL9A 2BWUA 2GA2A 4U6JA 4A6WA 4IECA 3CB6A 2B3LA 2BN7A 4S00A 1KQ9A 4Z7MA 2Q92A 4IPAA 5CIKA 2GG2A 1WKMA 3QOCA 3PKEA 4ZWPA 4PV4A 1B59A 2B3KA 4U71A 4U6EA 1KP0A 5CDEA 1O0XA 4S2TP 2GG0A 4OOKA 5CDLA 2BWSA 2GU4A 4IU6A 2EVOA 1WN1A 4RGZ1 1QXYA 2GU5A 2BHBA 3IL0A 3D27A 2GG9A 1B6AA 4IKSA 2P99A 4PNCA 5CDVA 1YJ3A 2G6PA 4FLIA 2P9AA 3PN9A 1BOAA 2V6CA 4IF7A 1WLRA 3OOOA 2EA2A 3PKDA 5CE6A 5E2CA 4U6ZA 4ZWOA 5CNXA 4B28A 4JUQA 2GG8A 5FCHA 2GG5A 2IW2A 3PEBA 1R5GA 4U69A 1YVMA 3OVKA 2OAZA 2BWWA 4U6CA 5JHUA 5JI6A 3PKCA 5CLSA 1PV9A 3MX6A 1M35A 5E5BA 2P98A 5JFRA 4U1BA 4RZZA 3TB5A 3FM3A 1WBQA 2Q94A 1XGSA 3MATA 2V3ZA 3BIPA 2GU7A 3FMQA 4MATA 3IU9A 1R5HA 4U70A 4U6WA 2Q95A 4RZYA 4FO8A 3CTZA 3I7MA 2HOWA 4R60A 2B3HA 2GGCA 2BH3A 2BWVA 2MATA 4ZWUA 2BWTA 2EVMA 1R58A 1C23A 1YW7A 4U75A 2GG7A 1JAWA 2GU6A 4IDYA 1Y1NA 4FO7A 4S2RP 2Q8KA 1QZYA 1YW8A 2BHCA 2BWXA 5FCFA 3IU7A 4FLLA 4IKUA 1BN5A 3FMRA 4QR8A 1QXWA 1YW9A 2NQ6A 4FLKA 3TAVA 4IKRA 3Q6DA 2Q96A 2GG3A 4IKTA 3IG4A 5D6FA 1A16A 2EA4A 3BITA 3L24A 1W2MA 1WL6A 2BHDA 1MATA 2GZ5A 3MR1A 1XGMA 4KM3A 2EVCA 4U76A 3S6BA 1N51A 2DFIA 2ZSGA 1XGNA 2OKNA 4U73A 3PKAA 4FKCA 1QXZA 2V3XA 1WY2A 1W7VA 3IU8A 2GTXA 4FUKA 2Q93A 4S01A 2BHAA 2GGBA 4A6VA 1CHMA 2NQ7A 3BIQA 2V3YA 3PKBA 1XGOA 3RORA 2ADUA 4FLJA 4ZNGA 1C27A 1C24A 5D6EA 2BB7A 2BWYA 1XNZA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3CB5 A;  1KQ0 A;  3RVA A;  1C22 A;  4HXX A;  3L7G A;  4EGE A;  1C21 A;  3O5V A;  1WL9 A;  2BWU A;  2GA2 A;  4U6J A;  4A6W A;  4IEC A;  3CB6 A;  2B3L A;  2BN7 A;  4S00 A;  1KQ9 A;  4Z7M A;  2Q92 A;  4IPA A;  5CIK A;  2GG2 A;  1WKM A;  3QOC A;  3PKE A;  4ZWP A;  4PV4 A;  1B59 A;  2B3K A;  4U71 A;  4U6E A;  1KP0 A;  5CDE A;  1O0X A;  4S2T P;  2GG0 A;  4OOK A;  5CDL A;  2BWS A;  2GU4 A;  4IU6 A;  2EVO A;  1WN1 A;  4RGZ 1;  1QXY A;  2GU5 A;  2BHB A;  3IL0 A;  3D27 A;  2GG9 A;  1B6A A;  4IKS A;  2P99 A;  4PNC A;  5CDV A;  1YJ3 A;  2G6P A;  4FLI A;  2P9A A;  3PN9 A;  1BOA A;  2V6C A;  4IF7 A;  1WLR A;  3OOO A;  2EA2 A;  3PKD A;  5CE6 A;  5E2C A;  4U6Z A;  4ZWO A;  5CNX A;  4B28 A;  4JUQ A;  2GG8 A;  5FCH A;  2GG5 A;  2IW2 A;  3PEB A;  1R5G A;  4U69 A;  1YVM A;  3OVK A;  2OAZ A;  2BWW A;  4U6C A;  5JHU A;  5JI6 A;  3PKC A;  5CLS A;  1PV9 A;  3MX6 A;  1M35 A;  5E5B A;  2P98 A;  5JFR A;  4U1B A;  4RZZ A;  3TB5 A;  3FM3 A;  1WBQ A;  2Q94 A;  1XGS A;  3MAT A;  2V3Z A;  3BIP A;  2GU7 A;  3FMQ A;  4MAT A;  3IU9 A;  1R5H A;  4U70 A;  4U6W A;  2Q95 A;  4RZY A;  4FO8 A;  3CTZ A;  3I7M A;  2HOW A;  4R60 A;  2B3H A;  2GGC A;  2BH3 A;  2BWV A;  2MAT A;  4ZWU A;  2BWT A;  2EVM A;  1R58 A;  1C23 A;  1YW7 A;  4U75 A;  2GG7 A;  1JAW A;  2GU6 A;  4IDY A;  1Y1N A;  4FO7 A;  4S2R P;  2Q8K A;  1QZY A;  1YW8 A;  2BHC A;  2BWX A;  5FCF A;  3IU7 A;  4FLL A;  4IKU A;  1BN5 A;  3FMR A;  4QR8 A;  1QXW A;  1YW9 A;  2NQ6 A;  4FLK A;  3TAV A;  4IKR A;  3Q6D A;  2Q96 A;  2GG3 A;  4IKT A;  3IG4 A;  5D6F A;  1A16 A;  2EA4 A;  3BIT A;  3L24 A;  1W2M A;  1WL6 A;  2BHD A;  1MAT A;  2GZ5 A;  3MR1 A;  1XGM A;  4KM3 A;  2EVC A;  4U76 A;  3S6B A;  1N51 A;  2DFI A;  2ZSG A;  1XGN A;  2OKN A;  4U73 A;  3PKA A;  4FKC A;  1QXZ A;  2V3X A;  1WY2 A;  1W7V A;  3IU8 A;  2GTX A;  4FUK A;  2Q93 A;  4S01 A;  2BHA A;  2GGB A;  4A6V A;  1CHM A;  2NQ7 A;  3BIQ A;  2V3Y A;  3PKB A;  1XGO A;  3ROR A;  2ADU A;  4FLJ A;  4ZNG A;  1C27 A;  1C24 A;  5D6E A;  2BB7 A;  2BWY A;  1XNZ A; 
#chains in the Genus database with same CATH topology
 3CB5 A;  1KQ0 A;  3RVA A;  1C22 A;  4HXX A;  3L7G A;  4EGE A;  1C21 A;  3O5V A;  1WL9 A;  2BWU A;  2GA2 A;  4U6J A;  4A6W A;  4IEC A;  3CB6 A;  2B3L A;  2BN7 A;  4S00 A;  1KQ9 A;  4Z7M A;  2Q92 A;  4IPA A;  5CIK A;  2GG2 A;  1WKM A;  3QOC A;  3PKE A;  4ZWP A;  4PV4 A;  1B59 A;  2B3K A;  4U71 A;  4U6E A;  1KP0 A;  5CDE A;  1O0X A;  4S2T P;  2GG0 A;  4OOK A;  5CDL A;  2BWS A;  2GU4 A;  4IU6 A;  2EVO A;  1WN1 A;  4RGZ 1;  1QXY A;  2GU5 A;  2BHB A;  3IL0 A;  3D27 A;  2GG9 A;  1B6A A;  4IKS A;  2P99 A;  4PNC A;  5CDV A;  1YJ3 A;  2G6P A;  4FLI A;  2P9A A;  3PN9 A;  1BOA A;  2V6C A;  4IF7 A;  1WLR A;  3OOO A;  2EA2 A;  3PKD A;  5CE6 A;  5E2C A;  4U6Z A;  4ZWO A;  5CNX A;  4B28 A;  4JUQ A;  2GG8 A;  5FCH A;  2GG5 A;  2IW2 A;  3PEB A;  1R5G A;  4U69 A;  1YVM A;  3OVK A;  2OAZ A;  2BWW A;  4U6C A;  5JHU A;  5JI6 A;  3PKC A;  5CLS A;  1PV9 A;  3MX6 A;  1M35 A;  5E5B A;  2P98 A;  5JFR A;  4U1B A;  4RZZ A;  3TB5 A;  3FM3 A;  1WBQ A;  2Q94 A;  1XGS A;  3MAT A;  2V3Z A;  3BIP A;  2GU7 A;  3FMQ A;  4MAT A;  3IU9 A;  1R5H A;  4U70 A;  4U6W A;  2Q95 A;  4RZY A;  4FO8 A;  3CTZ A;  3I7M A;  2HOW A;  4R60 A;  2B3H A;  2GGC A;  2BH3 A;  2BWV A;  2MAT A;  4ZWU A;  2BWT A;  2EVM A;  1R58 A;  1C23 A;  1YW7 A;  4U75 A;  2GG7 A;  1JAW A;  2GU6 A;  4IDY A;  1Y1N A;  4FO7 A;  4S2R P;  2Q8K A;  1QZY A;  1YW8 A;  2BHC A;  2BWX A;  5FCF A;  3IU7 A;  4FLL A;  4IKU A;  1BN5 A;  3FMR A;  4QR8 A;  1QXW A;  1YW9 A;  2NQ6 A;  4FLK A;  3TAV A;  4IKR A;  3Q6D A;  2Q96 A;  2GG3 A;  4IKT A;  3IG4 A;  5D6F A;  1A16 A;  2EA4 A;  3BIT A;  3L24 A;  1W2M A;  1WL6 A;  2BHD A;  1MAT A;  2GZ5 A;  3MR1 A;  1XGM A;  4KM3 A;  2EVC A;  4U76 A;  3S6B A;  1N51 A;  2DFI A;  2ZSG A;  1XGN A;  2OKN A;  4U73 A;  3PKA A;  4FKC A;  1QXZ A;  2V3X A;  1WY2 A;  1W7V A;  3IU8 A;  2GTX A;  4FUK A;  2Q93 A;  4S01 A;  2BHA A;  2GGB A;  4A6V A;  1CHM A;  2NQ7 A;  3BIQ A;  2V3Y A;  3PKB A;  1XGO A;  3ROR A;  2ADU A;  4FLJ A;  4ZNG A;  1C27 A;  1C24 A;  5D6E A;  2BB7 A;  2BWY A;  1XNZ A; 
#chains in the Genus database with same CATH homology
 3CB5 A;  1KQ0 A;  3RVA A;  1C22 A;  4HXX A;  3L7G A;  4EGE A;  1C21 A;  3O5V A;  1WL9 A;  2BWU A;  2GA2 A;  4U6J A;  4A6W A;  4IEC A;  3CB6 A;  2B3L A;  2BN7 A;  4S00 A;  1KQ9 A;  4Z7M A;  2Q92 A;  4IPA A;  5CIK A;  2GG2 A;  1WKM A;  3QOC A;  3PKE A;  4ZWP A;  4PV4 A;  1B59 A;  2B3K A;  4U71 A;  4U6E A;  1KP0 A;  5CDE A;  1O0X A;  4S2T P;  2GG0 A;  4OOK A;  5CDL A;  2BWS A;  2GU4 A;  4IU6 A;  2EVO A;  1WN1 A;  4RGZ 1;  1QXY A;  2GU5 A;  2BHB A;  3IL0 A;  3D27 A;  2GG9 A;  1B6A A;  4IKS A;  2P99 A;  4PNC A;  5CDV A;  1YJ3 A;  2G6P A;  4FLI A;  2P9A A;  3PN9 A;  1BOA A;  2V6C A;  4IF7 A;  1WLR A;  3OOO A;  2EA2 A;  3PKD A;  5CE6 A;  5E2C A;  4U6Z A;  4ZWO A;  5CNX A;  4B28 A;  4JUQ A;  2GG8 A;  5FCH A;  2GG5 A;  2IW2 A;  3PEB A;  1R5G A;  4U69 A;  1YVM A;  3OVK A;  2OAZ A;  2BWW A;  4U6C A;  5JHU A;  5JI6 A;  3PKC A;  5CLS A;  1PV9 A;  3MX6 A;  1M35 A;  5E5B A;  2P98 A;  5JFR A;  4U1B A;  4RZZ A;  3TB5 A;  3FM3 A;  1WBQ A;  2Q94 A;  1XGS A;  3MAT A;  2V3Z A;  3BIP A;  2GU7 A;  3FMQ A;  4MAT A;  3IU9 A;  1R5H A;  4U70 A;  4U6W A;  2Q95 A;  4RZY A;  4FO8 A;  3CTZ A;  3I7M A;  2HOW A;  4R60 A;  2B3H A;  2GGC A;  2BH3 A;  2BWV A;  2MAT A;  4ZWU A;  2BWT A;  2EVM A;  1R58 A;  1C23 A;  1YW7 A;  4U75 A;  2GG7 A;  1JAW A;  2GU6 A;  4IDY A;  1Y1N A;  4FO7 A;  4S2R P;  2Q8K A;  1QZY A;  1YW8 A;  2BHC A;  2BWX A;  5FCF A;  3IU7 A;  4FLL A;  4IKU A;  1BN5 A;  3FMR A;  4QR8 A;  1QXW A;  1YW9 A;  2NQ6 A;  4FLK A;  3TAV A;  4IKR A;  3Q6D A;  2Q96 A;  2GG3 A;  4IKT A;  3IG4 A;  5D6F A;  1A16 A;  2EA4 A;  3BIT A;  3L24 A;  1W2M A;  1WL6 A;  2BHD A;  1MAT A;  2GZ5 A;  3MR1 A;  1XGM A;  4KM3 A;  2EVC A;  4U76 A;  3S6B A;  1N51 A;  2DFI A;  2ZSG A;  1XGN A;  2OKN A;  4U73 A;  3PKA A;  4FKC A;  1QXZ A;  2V3X A;  1WY2 A;  1W7V A;  3IU8 A;  2GTX A;  4FUK A;  2Q93 A;  4S01 A;  2BHA A;  2GGB A;  4A6V A;  1CHM A;  2NQ7 A;  3BIQ A;  2V3Y A;  3PKB A;  1XGO A;  3ROR A;  2ADU A;  4FLJ A;  4ZNG A;  1C27 A;  1C24 A;  5D6E A;  2BB7 A;  2BWY A;  1XNZ A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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