1WY2A

Crystal structure of the prolidase from pyrococcus horikoshii ot3
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
351
structure length
351
Chain Sequence
MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
publication title Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Hydrolase
total genus 126
structure length 351
sequence length 351
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2005-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wy2A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wy2A02
5CE6A 2B3KA 2Q8KA 1W2MA 4U6JA 4A6VA 5JI6A 1C23A 2BB7A 4U6EA 1C27A 2BN7A 2EVMA 1XNZA 1WL6A 3FM3A 3IU9A 4KM3A 2V3XA 4RZYA 2NQ6A 2BHDA 4S2TP 1XGSA 2EA4A 1M35A 1YVMA 1WL9A 3PKAA 4JUQA 1WN1A 2GU5A 2GU7A 1R5HA 4A6WA 3IG4A 5CDEA 4IDYA 4FUKA 3L24A 1QXWA 2GTXA 2GZ5A 3PEBA 3CB6A 2Q92A 2EVOA 2GGBA 1B6AA 1KQ0A 3I7MA 3PN9A 5FCHA 1BOAA 2BHAA 2NQ7A 3MR1A 4ZWPA 3IU7A 1YJ3A 2GGCA 4FLLA 3O5VA 2GG3A 5JFRA 4IKUA 4ZWUA 2GG0A 4PNCA 4IPAA 2V6CA 2BHCA 4U6ZA 4RGZ1 1XGNA 4U1BA 1C24A 2B3LA 3PKDA 3FMRA 1KP0A 4ZNGA 3BIPA 5E5BA 5FCFA 4HXXA 3QOCA 2ADUA 4U69A 1Y1NA 3TAVA 1WLRA 3CB5A 1XGOA 3BIQA 2Q95A 2BWSA 2GG2A 3IL0A 1O0XA 4U75A 2BWXA 1BN5A 2GU6A 3PKEA 4U6WA 2V3YA 4S2RP 4U76A 5D6FA 3OOOA 1QXZA 2MATA 3RVAA 2GG5A 4IECA 1XGMA 1WY2A 4IU6A 4EGEA 2Q94A 4U73A 3FMQA 4FO8A 4IKSA 2HOWA 2G6PA 4IF7A 1PV9A 1YW8A 4U6CA 2ZSGA 2IW2A 1WBQA 2DFIA 2EVCA 1QZYA 2GA2A 4OOKA 2BWTA 2Q93A 1R58A 4FO7A 4FLIA 1N51A 1MATA 4MATA 4R60A 1B59A 3RORA 1W7VA 3MX6A 2Q96A 4S00A 1C22A 2OKNA 2BHBA 3Q6DA 1WKMA 1QXYA 5JHUA 1C21A 1CHMA 4Z7MA 3S6BA 2BWVA 2GU4A 3TB5A 2EA2A 2V3ZA 5CDLA 2OAZA 2GG9A 2B3HA 1YW9A 2BWUA 4FKCA 4PV4A 4S01A 3CTZA 2P99A 4U71A 5CLSA 4B28A 2BWWA 3PKCA 1YW7A 1A16A 5CNXA 4IKRA 5CDVA 4U70A 1JAWA 1R5GA 3D27A 3L7GA 5CIKA 3MATA 4QR8A 5D6EA 4IKTA 2BWYA 2P98A 3IU8A 2P9AA 5E2CA 3BITA 2GG7A 2BH3A 4ZWOA 1KQ9A 3PKBA 2GG8A 4FLKA 4RZZA 3OVKA 4FLJA
chains in the Genus database with same CATH superfamily
5CE6A 2B3KA 2Q8KA 1W2MA 4U6JA 4A6VA 5JI6A 1C23A 2BB7A 4U6EA 1C27A 2BN7A 2EVMA 1XNZA 1WL6A 3FM3A 3IU9A 4KM3A 2V3XA 4RZYA 2NQ6A 2BHDA 4S2TP 1XGSA 2EA4A 1M35A 1YVMA 1WL9A 3PKAA 4JUQA 1WN1A 2GU5A 2GU7A 1R5HA 4A6WA 3IG4A 5CDEA 4IDYA 4FUKA 3L24A 1QXWA 2GTXA 2GZ5A 3PEBA 3CB6A 2Q92A 2EVOA 2GGBA 1B6AA 1KQ0A 3I7MA 3PN9A 5FCHA 1BOAA 2BHAA 2NQ7A 3MR1A 4ZWPA 3IU7A 1YJ3A 2GGCA 4FLLA 3O5VA 2GG3A 5JFRA 4IKUA 4ZWUA 2GG0A 4PNCA 4IPAA 2V6CA 2BHCA 4U6ZA 4RGZ1 1XGNA 4U1BA 1C24A 2B3LA 3PKDA 3FMRA 1KP0A 4ZNGA 3BIPA 5E5BA 5FCFA 4HXXA 3QOCA 2ADUA 4U69A 1Y1NA 3TAVA 1WLRA 3CB5A 1XGOA 3BIQA 2Q95A 2BWSA 2GG2A 3IL0A 1O0XA 4U75A 2BWXA 1BN5A 2GU6A 3PKEA 4U6WA 2V3YA 4S2RP 4U76A 5D6FA 3OOOA 1QXZA 2MATA 3RVAA 2GG5A 4IECA 1XGMA 1WY2A 4IU6A 4EGEA 2Q94A 4U73A 3FMQA 4FO8A 4IKSA 2HOWA 2G6PA 4IF7A 1PV9A 1YW8A 4U6CA 2ZSGA 2IW2A 1WBQA 2DFIA 2EVCA 1QZYA 2GA2A 4OOKA 2BWTA 2Q93A 1R58A 4FO7A 4FLIA 1N51A 1MATA 4MATA 4R60A 1B59A 3RORA 1W7VA 3MX6A 2Q96A 4S00A 1C22A 2OKNA 2BHBA 3Q6DA 1WKMA 1QXYA 5JHUA 1C21A 1CHMA 4Z7MA 3S6BA 2BWVA 2GU4A 3TB5A 2EA2A 2V3ZA 5CDLA 2OAZA 2GG9A 2B3HA 1YW9A 2BWUA 4FKCA 4PV4A 4S01A 3CTZA 2P99A 4U71A 5CLSA 4B28A 2BWWA 3PKCA 1YW7A 1A16A 5CNXA 4IKRA 5CDVA 4U70A 1JAWA 1R5GA 3D27A 3L7GA 5CIKA 3MATA 4QR8A 5D6EA 4IKTA 2BWYA 2P98A 3IU8A 2P9AA 5E2CA 3BITA 2GG7A 2BH3A 4ZWOA 1KQ9A 3PKBA 2GG8A 4FLKA 4RZZA 3OVKA 4FLJA
chains in the Genus database with same CATH topology
5CE6A 2B3KA 2Q8KA 1W2MA 4U6JA 4A6VA 5JI6A 1C23A 2BB7A 4U6EA 1C27A 2BN7A 2EVMA 1XNZA 1WL6A 3FM3A 3IU9A 4KM3A 2V3XA 4RZYA 2NQ6A 2BHDA 4S2TP 1XGSA 2EA4A 1M35A 1YVMA 1WL9A 3PKAA 4JUQA 1WN1A 2GU5A 2GU7A 1R5HA 4A6WA 3IG4A 5CDEA 4IDYA 4FUKA 3L24A 1QXWA 2GTXA 2GZ5A 3PEBA 3CB6A 2Q92A 2EVOA 2GGBA 1B6AA 1KQ0A 3I7MA 3PN9A 5FCHA 1BOAA 2BHAA 2NQ7A 3MR1A 4ZWPA 3IU7A 1YJ3A 2GGCA 4FLLA 3O5VA 2GG3A 5JFRA 4IKUA 4ZWUA 2GG0A 4PNCA 4IPAA 2V6CA 2BHCA 4U6ZA 4RGZ1 1XGNA 4U1BA 1C24A 2B3LA 3PKDA 3FMRA 1KP0A 4ZNGA 3BIPA 5E5BA 5FCFA 4HXXA 3QOCA 2ADUA 4U69A 1Y1NA 3TAVA 1WLRA 3CB5A 1XGOA 3BIQA 2Q95A 2BWSA 2GG2A 3IL0A 1O0XA 4U75A 2BWXA 1BN5A 2GU6A 3PKEA 4U6WA 2V3YA 4S2RP 4U76A 5D6FA 3OOOA 1QXZA 2MATA 3RVAA 2GG5A 4IECA 1XGMA 1WY2A 4IU6A 4EGEA 2Q94A 4U73A 3FMQA 4FO8A 4IKSA 2HOWA 2G6PA 4IF7A 1PV9A 1YW8A 4U6CA 2ZSGA 2IW2A 1WBQA 2DFIA 2EVCA 1QZYA 2GA2A 4OOKA 2BWTA 2Q93A 1R58A 4FO7A 4FLIA 1N51A 1MATA 4MATA 4R60A 1B59A 3RORA 1W7VA 3MX6A 2Q96A 4S00A 1C22A 2OKNA 2BHBA 3Q6DA 1WKMA 1QXYA 5JHUA 1C21A 1CHMA 4Z7MA 3S6BA 2BWVA 2GU4A 3TB5A 2EA2A 2V3ZA 5CDLA 2OAZA 2GG9A 2B3HA 1YW9A 2BWUA 4FKCA 4PV4A 4S01A 3CTZA 2P99A 4U71A 5CLSA 4B28A 2BWWA 3PKCA 1YW7A 1A16A 5CNXA 4IKRA 5CDVA 4U70A 1JAWA 1R5GA 3D27A 3L7GA 5CIKA 3MATA 4QR8A 5D6EA 4IKTA 2BWYA 2P98A 3IU8A 2P9AA 5E2CA 3BITA 2GG7A 2BH3A 4ZWOA 1KQ9A 3PKBA 2GG8A 4FLKA 4RZZA 3OVKA 4FLJA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CE6 A;  2B3K A;  2Q8K A;  1W2M A;  4U6J A;  4A6V A;  5JI6 A;  1C23 A;  2BB7 A;  4U6E A;  1C27 A;  2BN7 A;  2EVM A;  1XNZ A;  1WL6 A;  3FM3 A;  3IU9 A;  4KM3 A;  2V3X A;  4RZY A;  2NQ6 A;  2BHD A;  4S2T P;  1XGS A;  2EA4 A;  1M35 A;  1YVM A;  1WL9 A;  3PKA A;  4JUQ A;  1WN1 A;  2GU5 A;  2GU7 A;  1R5H A;  4A6W A;  3IG4 A;  5CDE A;  4IDY A;  4FUK A;  3L24 A;  1QXW A;  2GTX A;  2GZ5 A;  3PEB A;  3CB6 A;  2Q92 A;  2EVO A;  2GGB A;  1B6A A;  1KQ0 A;  3I7M A;  3PN9 A;  5FCH A;  1BOA A;  2BHA A;  2NQ7 A;  3MR1 A;  4ZWP A;  3IU7 A;  1YJ3 A;  2GGC A;  4FLL A;  3O5V A;  2GG3 A;  5JFR A;  4IKU A;  4ZWU A;  2GG0 A;  4PNC A;  4IPA A;  2V6C A;  2BHC A;  4U6Z A;  4RGZ 1;  1XGN A;  4U1B A;  1C24 A;  2B3L A;  3PKD A;  3FMR A;  1KP0 A;  4ZNG A;  3BIP A;  5E5B A;  5FCF A;  4HXX A;  3QOC A;  2ADU A;  4U69 A;  1Y1N A;  3TAV A;  1WLR A;  3CB5 A;  1XGO A;  3BIQ A;  2Q95 A;  2BWS A;  2GG2 A;  3IL0 A;  1O0X A;  4U75 A;  2BWX A;  1BN5 A;  2GU6 A;  3PKE A;  4U6W A;  2V3Y A;  4S2R P;  4U76 A;  5D6F A;  3OOO A;  1QXZ A;  2MAT A;  3RVA A;  2GG5 A;  4IEC A;  1XGM A;  1WY2 A;  4IU6 A;  4EGE A;  2Q94 A;  4U73 A;  3FMQ A;  4FO8 A;  4IKS A;  2HOW A;  2G6P A;  4IF7 A;  1PV9 A;  1YW8 A;  4U6C A;  2ZSG A;  2IW2 A;  1WBQ A;  2DFI A;  2EVC A;  1QZY A;  2GA2 A;  4OOK A;  2BWT A;  2Q93 A;  1R58 A;  4FO7 A;  4FLI A;  1N51 A;  1MAT A;  4MAT A;  4R60 A;  1B59 A;  3ROR A;  1W7V A;  3MX6 A;  2Q96 A;  4S00 A;  1C22 A;  2OKN A;  2BHB A;  3Q6D A;  1WKM A;  1QXY A;  5JHU A;  1C21 A;  1CHM A;  4Z7M A;  3S6B A;  2BWV A;  2GU4 A;  3TB5 A;  2EA2 A;  2V3Z A;  5CDL A;  2OAZ A;  2GG9 A;  2B3H A;  1YW9 A;  2BWU A;  4FKC A;  4PV4 A;  4S01 A;  3CTZ A;  2P99 A;  4U71 A;  5CLS A;  4B28 A;  2BWW A;  3PKC A;  1YW7 A;  1A16 A;  5CNX A;  4IKR A;  5CDV A;  4U70 A;  1JAW A;  1R5G A;  3D27 A;  3L7G A;  5CIK A;  3MAT A;  4QR8 A;  5D6E A;  4IKT A;  2BWY A;  2P98 A;  3IU8 A;  2P9A A;  5E2C A;  3BIT A;  2GG7 A;  2BH3 A;  4ZWO A;  1KQ9 A;  3PKB A;  2GG8 A;  4FLK A;  4RZZ A;  3OVK A;  4FLJ A; 
#chains in the Genus database with same CATH topology
 5CE6 A;  2B3K A;  2Q8K A;  1W2M A;  4U6J A;  4A6V A;  5JI6 A;  1C23 A;  2BB7 A;  4U6E A;  1C27 A;  2BN7 A;  2EVM A;  1XNZ A;  1WL6 A;  3FM3 A;  3IU9 A;  4KM3 A;  2V3X A;  4RZY A;  2NQ6 A;  2BHD A;  4S2T P;  1XGS A;  2EA4 A;  1M35 A;  1YVM A;  1WL9 A;  3PKA A;  4JUQ A;  1WN1 A;  2GU5 A;  2GU7 A;  1R5H A;  4A6W A;  3IG4 A;  5CDE A;  4IDY A;  4FUK A;  3L24 A;  1QXW A;  2GTX A;  2GZ5 A;  3PEB A;  3CB6 A;  2Q92 A;  2EVO A;  2GGB A;  1B6A A;  1KQ0 A;  3I7M A;  3PN9 A;  5FCH A;  1BOA A;  2BHA A;  2NQ7 A;  3MR1 A;  4ZWP A;  3IU7 A;  1YJ3 A;  2GGC A;  4FLL A;  3O5V A;  2GG3 A;  5JFR A;  4IKU A;  4ZWU A;  2GG0 A;  4PNC A;  4IPA A;  2V6C A;  2BHC A;  4U6Z A;  4RGZ 1;  1XGN A;  4U1B A;  1C24 A;  2B3L A;  3PKD A;  3FMR A;  1KP0 A;  4ZNG A;  3BIP A;  5E5B A;  5FCF A;  4HXX A;  3QOC A;  2ADU A;  4U69 A;  1Y1N A;  3TAV A;  1WLR A;  3CB5 A;  1XGO A;  3BIQ A;  2Q95 A;  2BWS A;  2GG2 A;  3IL0 A;  1O0X A;  4U75 A;  2BWX A;  1BN5 A;  2GU6 A;  3PKE A;  4U6W A;  2V3Y A;  4S2R P;  4U76 A;  5D6F A;  3OOO A;  1QXZ A;  2MAT A;  3RVA A;  2GG5 A;  4IEC A;  1XGM A;  1WY2 A;  4IU6 A;  4EGE A;  2Q94 A;  4U73 A;  3FMQ A;  4FO8 A;  4IKS A;  2HOW A;  2G6P A;  4IF7 A;  1PV9 A;  1YW8 A;  4U6C A;  2ZSG A;  2IW2 A;  1WBQ A;  2DFI A;  2EVC A;  1QZY A;  2GA2 A;  4OOK A;  2BWT A;  2Q93 A;  1R58 A;  4FO7 A;  4FLI A;  1N51 A;  1MAT A;  4MAT A;  4R60 A;  1B59 A;  3ROR A;  1W7V A;  3MX6 A;  2Q96 A;  4S00 A;  1C22 A;  2OKN A;  2BHB A;  3Q6D A;  1WKM A;  1QXY A;  5JHU A;  1C21 A;  1CHM A;  4Z7M A;  3S6B A;  2BWV A;  2GU4 A;  3TB5 A;  2EA2 A;  2V3Z A;  5CDL A;  2OAZ A;  2GG9 A;  2B3H A;  1YW9 A;  2BWU A;  4FKC A;  4PV4 A;  4S01 A;  3CTZ A;  2P99 A;  4U71 A;  5CLS A;  4B28 A;  2BWW A;  3PKC A;  1YW7 A;  1A16 A;  5CNX A;  4IKR A;  5CDV A;  4U70 A;  1JAW A;  1R5G A;  3D27 A;  3L7G A;  5CIK A;  3MAT A;  4QR8 A;  5D6E A;  4IKT A;  2BWY A;  2P98 A;  3IU8 A;  2P9A A;  5E2C A;  3BIT A;  2GG7 A;  2BH3 A;  4ZWO A;  1KQ9 A;  3PKB A;  2GG8 A;  4FLK A;  4RZZ A;  3OVK A;  4FLJ A; 
#chains in the Genus database with same CATH homology
 5CE6 A;  2B3K A;  2Q8K A;  1W2M A;  4U6J A;  4A6V A;  5JI6 A;  1C23 A;  2BB7 A;  4U6E A;  1C27 A;  2BN7 A;  2EVM A;  1XNZ A;  1WL6 A;  3FM3 A;  3IU9 A;  4KM3 A;  2V3X A;  4RZY A;  2NQ6 A;  2BHD A;  4S2T P;  1XGS A;  2EA4 A;  1M35 A;  1YVM A;  1WL9 A;  3PKA A;  4JUQ A;  1WN1 A;  2GU5 A;  2GU7 A;  1R5H A;  4A6W A;  3IG4 A;  5CDE A;  4IDY A;  4FUK A;  3L24 A;  1QXW A;  2GTX A;  2GZ5 A;  3PEB A;  3CB6 A;  2Q92 A;  2EVO A;  2GGB A;  1B6A A;  1KQ0 A;  3I7M A;  3PN9 A;  5FCH A;  1BOA A;  2BHA A;  2NQ7 A;  3MR1 A;  4ZWP A;  3IU7 A;  1YJ3 A;  2GGC A;  4FLL A;  3O5V A;  2GG3 A;  5JFR A;  4IKU A;  4ZWU A;  2GG0 A;  4PNC A;  4IPA A;  2V6C A;  2BHC A;  4U6Z A;  4RGZ 1;  1XGN A;  4U1B A;  1C24 A;  2B3L A;  3PKD A;  3FMR A;  1KP0 A;  4ZNG A;  3BIP A;  5E5B A;  5FCF A;  4HXX A;  3QOC A;  2ADU A;  4U69 A;  1Y1N A;  3TAV A;  1WLR A;  3CB5 A;  1XGO A;  3BIQ A;  2Q95 A;  2BWS A;  2GG2 A;  3IL0 A;  1O0X A;  4U75 A;  2BWX A;  1BN5 A;  2GU6 A;  3PKE A;  4U6W A;  2V3Y A;  4S2R P;  4U76 A;  5D6F A;  3OOO A;  1QXZ A;  2MAT A;  3RVA A;  2GG5 A;  4IEC A;  1XGM A;  1WY2 A;  4IU6 A;  4EGE A;  2Q94 A;  4U73 A;  3FMQ A;  4FO8 A;  4IKS A;  2HOW A;  2G6P A;  4IF7 A;  1PV9 A;  1YW8 A;  4U6C A;  2ZSG A;  2IW2 A;  1WBQ A;  2DFI A;  2EVC A;  1QZY A;  2GA2 A;  4OOK A;  2BWT A;  2Q93 A;  1R58 A;  4FO7 A;  4FLI A;  1N51 A;  1MAT A;  4MAT A;  4R60 A;  1B59 A;  3ROR A;  1W7V A;  3MX6 A;  2Q96 A;  4S00 A;  1C22 A;  2OKN A;  2BHB A;  3Q6D A;  1WKM A;  1QXY A;  5JHU A;  1C21 A;  1CHM A;  4Z7M A;  3S6B A;  2BWV A;  2GU4 A;  3TB5 A;  2EA2 A;  2V3Z A;  5CDL A;  2OAZ A;  2GG9 A;  2B3H A;  1YW9 A;  2BWU A;  4FKC A;  4PV4 A;  4S01 A;  3CTZ A;  2P99 A;  4U71 A;  5CLS A;  4B28 A;  2BWW A;  3PKC A;  1YW7 A;  1A16 A;  5CNX A;  4IKR A;  5CDV A;  4U70 A;  1JAW A;  1R5G A;  3D27 A;  3L7G A;  5CIK A;  3MAT A;  4QR8 A;  5D6E A;  4IKT A;  2BWY A;  2P98 A;  3IU8 A;  2P9A A;  5E2C A;  3BIT A;  2GG7 A;  2BH3 A;  4ZWO A;  1KQ9 A;  3PKB A;  2GG8 A;  4FLK A;  4RZZ A;  3OVK A;  4FLJ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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