1WY2A

Crystal structure of the prolidase from pyrococcus horikoshii ot3
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
351
structure length
351
Chain Sequence
b'MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI'
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Xaa-Pro dipeptidase
publication title Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
molecule tags Hydrolase
total genus 126
structure length 351
sequence length 351
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2005-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wy2A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wy2A02
3PKAA 3MX6A 2BHDA 1MATA 3IG4A 2V3YA 2GU4A 2BHBA 4KM3A 4FLLA 1KQ9A 2V6CA 5CNXA 2BWUA 3IL0A 2BWVA 4FUKA 2V3ZA 2OAZA 5CLSA 2GG8A 2P99A 1WKMA 5CE6A 1CHMA 1O0XA 2GG2A 1R5GA 2GG9A 4RZYA 1C27A 4ZWOA 2NQ6A 3PKEA 3FM3A 2GU7A 2ADUA 2EA4A 3TAVA 2Q93A 4RGZ1 2GGBA 1QXYA 3IU7A 2GG7A 2P98A 1QZYA 2BWSA 4QR8A 3OOOA 3L24A 4FLKA 4IKTA 4B28A 3L7GA 2BWYA 5CDEA 2DFIA 3IU9A 4FKCA 2MATA 1XGMA 2GGCA 1BOAA 2GZ5A 1WN1A 2GU6A 1R58A 3OVKA 4S2RP 1C22A 1JAWA 1W7VA 1QXZA 4Z7MA 3PEBA 4R60A 2V3XA 1WL6A 4U6CA 1YW8A 4IDYA 3IU8A 3D27A 3QOCA 2GG5A 5CDLA 1Y1NA 1XGSA 2G6PA 5JI6A 1YJ3A 4FLJA 3PN9A 1N51A 3PKDA 4U6ZA 5JHUA 1YW9A 1WY2A 3Q6DA 1YW7A 3RVAA 2B3KA 2EVMA 3CB6A 1XGNA 3PKCA 2BWTA 1YVMA 4IKUA 4U70A 4RZZA 2Q92A 5D6EA 2BWXA 4MATA 2HOWA 3BITA 2EVOA 2GG3A 4JUQA 3BIQA 1R5HA 2Q94A 4U75A 1W2MA 3FMQA 2Q8KA 3CB5A 2Q96A 2NQ7A 5FCFA 4S01A 4ZWUA 4IU6A 4U6JA 5FCHA 3PKBA 1QXWA 4IPAA 2Q95A 1M35A 5CIKA 4U69A 4ZNGA 4OOKA 4PV4A 2GA2A 2BN7A 1PV9A 4S00A 3RORA 3CTZA 2BH3A 4A6WA 1BN5A 4U76A 1KQ0A 2BHCA 5E2CA 4U1BA 1B59A 3I7MA 4U6WA 4PNCA 2GG0A 1WL9A 5D6FA 1WLRA 2OKNA 1WBQA 4IKRA 1A16A 4U71A 2ZSGA 4HXXA 4U73A 5JFRA 2IW2A 1KP0A 4EGEA 3FMRA 4FLIA 4U6EA 4A6VA 2B3HA 4IECA 3S6BA 1C21A 3MR1A 3BIPA 1C23A 2GTXA 4IF7A 2BWWA 4FO8A 2B3LA 2GU5A 5E5BA 1B6AA 3MATA 1C24A 4IKSA 1XNZA 2EA2A 3O5VA 2BHAA 2BB7A 2P9AA 5CDVA 4S2TP 3TB5A 2EVCA 4FO7A 1XGOA 4ZWPA
chains in the Genus database with same CATH superfamily
3PKAA 3MX6A 2BHDA 1MATA 3IG4A 2V3YA 2GU4A 2BHBA 4KM3A 4FLLA 1KQ9A 2V6CA 5CNXA 2BWUA 3IL0A 2BWVA 4FUKA 2V3ZA 2OAZA 5CLSA 2GG8A 2P99A 1WKMA 5CE6A 1CHMA 1O0XA 2GG2A 1R5GA 2GG9A 4RZYA 1C27A 4ZWOA 2NQ6A 3PKEA 3FM3A 2GU7A 2ADUA 2EA4A 3TAVA 2Q93A 4RGZ1 2GGBA 1QXYA 3IU7A 2GG7A 2P98A 1QZYA 2BWSA 4QR8A 3OOOA 3L24A 4FLKA 4IKTA 4B28A 3L7GA 2BWYA 5CDEA 2DFIA 3IU9A 4FKCA 2MATA 1XGMA 2GGCA 1BOAA 2GZ5A 1WN1A 2GU6A 1R58A 3OVKA 4S2RP 1C22A 1JAWA 1W7VA 1QXZA 4Z7MA 3PEBA 4R60A 2V3XA 1WL6A 4U6CA 1YW8A 4IDYA 3IU8A 3D27A 3QOCA 2GG5A 5CDLA 1Y1NA 1XGSA 2G6PA 5JI6A 1YJ3A 4FLJA 3PN9A 1N51A 3PKDA 4U6ZA 5JHUA 1YW9A 1WY2A 3Q6DA 1YW7A 3RVAA 2B3KA 2EVMA 3CB6A 1XGNA 3PKCA 2BWTA 1YVMA 4IKUA 4U70A 4RZZA 2Q92A 5D6EA 2BWXA 4MATA 2HOWA 3BITA 2EVOA 2GG3A 4JUQA 3BIQA 1R5HA 2Q94A 4U75A 1W2MA 3FMQA 2Q8KA 3CB5A 2Q96A 2NQ7A 5FCFA 4S01A 4ZWUA 4IU6A 4U6JA 5FCHA 3PKBA 1QXWA 4IPAA 2Q95A 1M35A 5CIKA 4U69A 4ZNGA 4OOKA 4PV4A 2GA2A 2BN7A 1PV9A 4S00A 3RORA 3CTZA 2BH3A 4A6WA 1BN5A 4U76A 1KQ0A 2BHCA 5E2CA 4U1BA 1B59A 3I7MA 4U6WA 4PNCA 2GG0A 1WL9A 5D6FA 1WLRA 2OKNA 1WBQA 4IKRA 1A16A 4U71A 2ZSGA 4HXXA 4U73A 5JFRA 2IW2A 1KP0A 4EGEA 3FMRA 4FLIA 4U6EA 4A6VA 2B3HA 4IECA 3S6BA 1C21A 3MR1A 3BIPA 1C23A 2GTXA 4IF7A 2BWWA 4FO8A 2B3LA 2GU5A 5E5BA 1B6AA 3MATA 1C24A 4IKSA 1XNZA 2EA2A 3O5VA 2BHAA 2BB7A 2P9AA 5CDVA 4S2TP 3TB5A 2EVCA 4FO7A 1XGOA 4ZWPA
chains in the Genus database with same CATH topology
3PKAA 3MX6A 2BHDA 1MATA 3IG4A 2V3YA 2GU4A 2BHBA 4KM3A 4FLLA 1KQ9A 2V6CA 5CNXA 2BWUA 3IL0A 2BWVA 4FUKA 2V3ZA 2OAZA 5CLSA 2GG8A 2P99A 1WKMA 5CE6A 1CHMA 1O0XA 2GG2A 1R5GA 2GG9A 4RZYA 1C27A 4ZWOA 2NQ6A 3PKEA 3FM3A 2GU7A 2ADUA 2EA4A 3TAVA 2Q93A 4RGZ1 2GGBA 1QXYA 3IU7A 2GG7A 2P98A 1QZYA 2BWSA 4QR8A 3OOOA 3L24A 4FLKA 4IKTA 4B28A 3L7GA 2BWYA 5CDEA 2DFIA 3IU9A 4FKCA 2MATA 1XGMA 2GGCA 1BOAA 2GZ5A 1WN1A 2GU6A 1R58A 3OVKA 4S2RP 1C22A 1JAWA 1W7VA 1QXZA 4Z7MA 3PEBA 4R60A 2V3XA 1WL6A 4U6CA 1YW8A 4IDYA 3IU8A 3D27A 3QOCA 2GG5A 5CDLA 1Y1NA 1XGSA 2G6PA 5JI6A 1YJ3A 4FLJA 3PN9A 1N51A 3PKDA 4U6ZA 5JHUA 1YW9A 1WY2A 3Q6DA 1YW7A 3RVAA 2B3KA 2EVMA 3CB6A 1XGNA 3PKCA 2BWTA 1YVMA 4IKUA 4U70A 4RZZA 2Q92A 5D6EA 2BWXA 4MATA 2HOWA 3BITA 2EVOA 2GG3A 4JUQA 3BIQA 1R5HA 2Q94A 4U75A 1W2MA 3FMQA 2Q8KA 3CB5A 2Q96A 2NQ7A 5FCFA 4S01A 4ZWUA 4IU6A 4U6JA 5FCHA 3PKBA 1QXWA 4IPAA 2Q95A 1M35A 5CIKA 4U69A 4ZNGA 4OOKA 4PV4A 2GA2A 2BN7A 1PV9A 4S00A 3RORA 3CTZA 2BH3A 4A6WA 1BN5A 4U76A 1KQ0A 2BHCA 5E2CA 4U1BA 1B59A 3I7MA 4U6WA 4PNCA 2GG0A 1WL9A 5D6FA 1WLRA 2OKNA 1WBQA 4IKRA 1A16A 4U71A 2ZSGA 4HXXA 4U73A 5JFRA 2IW2A 1KP0A 4EGEA 3FMRA 4FLIA 4U6EA 4A6VA 2B3HA 4IECA 3S6BA 1C21A 3MR1A 3BIPA 1C23A 2GTXA 4IF7A 2BWWA 4FO8A 2B3LA 2GU5A 5E5BA 1B6AA 3MATA 1C24A 4IKSA 1XNZA 2EA2A 3O5VA 2BHAA 2BB7A 2P9AA 5CDVA 4S2TP 3TB5A 2EVCA 4FO7A 1XGOA 4ZWPA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PKA A;  3MX6 A;  2BHD A;  1MAT A;  3IG4 A;  2V3Y A;  2GU4 A;  2BHB A;  4KM3 A;  4FLL A;  1KQ9 A;  2V6C A;  5CNX A;  2BWU A;  3IL0 A;  2BWV A;  4FUK A;  2V3Z A;  2OAZ A;  5CLS A;  2GG8 A;  2P99 A;  1WKM A;  5CE6 A;  1CHM A;  1O0X A;  2GG2 A;  1R5G A;  2GG9 A;  4RZY A;  1C27 A;  4ZWO A;  2NQ6 A;  3PKE A;  3FM3 A;  2GU7 A;  2ADU A;  2EA4 A;  3TAV A;  2Q93 A;  4RGZ 1;  2GGB A;  1QXY A;  3IU7 A;  2GG7 A;  2P98 A;  1QZY A;  2BWS A;  4QR8 A;  3OOO A;  3L24 A;  4FLK A;  4IKT A;  4B28 A;  3L7G A;  2BWY A;  5CDE A;  2DFI A;  3IU9 A;  4FKC A;  2MAT A;  1XGM A;  2GGC A;  1BOA A;  2GZ5 A;  1WN1 A;  2GU6 A;  1R58 A;  3OVK A;  4S2R P;  1C22 A;  1JAW A;  1W7V A;  1QXZ A;  4Z7M A;  3PEB A;  4R60 A;  2V3X A;  1WL6 A;  4U6C A;  1YW8 A;  4IDY A;  3IU8 A;  3D27 A;  3QOC A;  2GG5 A;  5CDL A;  1Y1N A;  1XGS A;  2G6P A;  5JI6 A;  1YJ3 A;  4FLJ A;  3PN9 A;  1N51 A;  3PKD A;  4U6Z A;  5JHU A;  1YW9 A;  1WY2 A;  3Q6D A;  1YW7 A;  3RVA A;  2B3K A;  2EVM A;  3CB6 A;  1XGN A;  3PKC A;  2BWT A;  1YVM A;  4IKU A;  4U70 A;  4RZZ A;  2Q92 A;  5D6E A;  2BWX A;  4MAT A;  2HOW A;  3BIT A;  2EVO A;  2GG3 A;  4JUQ A;  3BIQ A;  1R5H A;  2Q94 A;  4U75 A;  1W2M A;  3FMQ A;  2Q8K A;  3CB5 A;  2Q96 A;  2NQ7 A;  5FCF A;  4S01 A;  4ZWU A;  4IU6 A;  4U6J A;  5FCH A;  3PKB A;  1QXW A;  4IPA A;  2Q95 A;  1M35 A;  5CIK A;  4U69 A;  4ZNG A;  4OOK A;  4PV4 A;  2GA2 A;  2BN7 A;  1PV9 A;  4S00 A;  3ROR A;  3CTZ A;  2BH3 A;  4A6W A;  1BN5 A;  4U76 A;  1KQ0 A;  2BHC A;  5E2C A;  4U1B A;  1B59 A;  3I7M A;  4U6W A;  4PNC A;  2GG0 A;  1WL9 A;  5D6F A;  1WLR A;  2OKN A;  1WBQ A;  4IKR A;  1A16 A;  4U71 A;  2ZSG A;  4HXX A;  4U73 A;  5JFR A;  2IW2 A;  1KP0 A;  4EGE A;  3FMR A;  4FLI A;  4U6E A;  4A6V A;  2B3H A;  4IEC A;  3S6B A;  1C21 A;  3MR1 A;  3BIP A;  1C23 A;  2GTX A;  4IF7 A;  2BWW A;  4FO8 A;  2B3L A;  2GU5 A;  5E5B A;  1B6A A;  3MAT A;  1C24 A;  4IKS A;  1XNZ A;  2EA2 A;  3O5V A;  2BHA A;  2BB7 A;  2P9A A;  5CDV A;  4S2T P;  3TB5 A;  2EVC A;  4FO7 A;  1XGO A;  4ZWP A; 
#chains in the Genus database with same CATH topology
 3PKA A;  3MX6 A;  2BHD A;  1MAT A;  3IG4 A;  2V3Y A;  2GU4 A;  2BHB A;  4KM3 A;  4FLL A;  1KQ9 A;  2V6C A;  5CNX A;  2BWU A;  3IL0 A;  2BWV A;  4FUK A;  2V3Z A;  2OAZ A;  5CLS A;  2GG8 A;  2P99 A;  1WKM A;  5CE6 A;  1CHM A;  1O0X A;  2GG2 A;  1R5G A;  2GG9 A;  4RZY A;  1C27 A;  4ZWO A;  2NQ6 A;  3PKE A;  3FM3 A;  2GU7 A;  2ADU A;  2EA4 A;  3TAV A;  2Q93 A;  4RGZ 1;  2GGB A;  1QXY A;  3IU7 A;  2GG7 A;  2P98 A;  1QZY A;  2BWS A;  4QR8 A;  3OOO A;  3L24 A;  4FLK A;  4IKT A;  4B28 A;  3L7G A;  2BWY A;  5CDE A;  2DFI A;  3IU9 A;  4FKC A;  2MAT A;  1XGM A;  2GGC A;  1BOA A;  2GZ5 A;  1WN1 A;  2GU6 A;  1R58 A;  3OVK A;  4S2R P;  1C22 A;  1JAW A;  1W7V A;  1QXZ A;  4Z7M A;  3PEB A;  4R60 A;  2V3X A;  1WL6 A;  4U6C A;  1YW8 A;  4IDY A;  3IU8 A;  3D27 A;  3QOC A;  2GG5 A;  5CDL A;  1Y1N A;  1XGS A;  2G6P A;  5JI6 A;  1YJ3 A;  4FLJ A;  3PN9 A;  1N51 A;  3PKD A;  4U6Z A;  5JHU A;  1YW9 A;  1WY2 A;  3Q6D A;  1YW7 A;  3RVA A;  2B3K A;  2EVM A;  3CB6 A;  1XGN A;  3PKC A;  2BWT A;  1YVM A;  4IKU A;  4U70 A;  4RZZ A;  2Q92 A;  5D6E A;  2BWX A;  4MAT A;  2HOW A;  3BIT A;  2EVO A;  2GG3 A;  4JUQ A;  3BIQ A;  1R5H A;  2Q94 A;  4U75 A;  1W2M A;  3FMQ A;  2Q8K A;  3CB5 A;  2Q96 A;  2NQ7 A;  5FCF A;  4S01 A;  4ZWU A;  4IU6 A;  4U6J A;  5FCH A;  3PKB A;  1QXW A;  4IPA A;  2Q95 A;  1M35 A;  5CIK A;  4U69 A;  4ZNG A;  4OOK A;  4PV4 A;  2GA2 A;  2BN7 A;  1PV9 A;  4S00 A;  3ROR A;  3CTZ A;  2BH3 A;  4A6W A;  1BN5 A;  4U76 A;  1KQ0 A;  2BHC A;  5E2C A;  4U1B A;  1B59 A;  3I7M A;  4U6W A;  4PNC A;  2GG0 A;  1WL9 A;  5D6F A;  1WLR A;  2OKN A;  1WBQ A;  4IKR A;  1A16 A;  4U71 A;  2ZSG A;  4HXX A;  4U73 A;  5JFR A;  2IW2 A;  1KP0 A;  4EGE A;  3FMR A;  4FLI A;  4U6E A;  4A6V A;  2B3H A;  4IEC A;  3S6B A;  1C21 A;  3MR1 A;  3BIP A;  1C23 A;  2GTX A;  4IF7 A;  2BWW A;  4FO8 A;  2B3L A;  2GU5 A;  5E5B A;  1B6A A;  3MAT A;  1C24 A;  4IKS A;  1XNZ A;  2EA2 A;  3O5V A;  2BHA A;  2BB7 A;  2P9A A;  5CDV A;  4S2T P;  3TB5 A;  2EVC A;  4FO7 A;  1XGO A;  4ZWP A; 
#chains in the Genus database with same CATH homology
 3PKA A;  3MX6 A;  2BHD A;  1MAT A;  3IG4 A;  2V3Y A;  2GU4 A;  2BHB A;  4KM3 A;  4FLL A;  1KQ9 A;  2V6C A;  5CNX A;  2BWU A;  3IL0 A;  2BWV A;  4FUK A;  2V3Z A;  2OAZ A;  5CLS A;  2GG8 A;  2P99 A;  1WKM A;  5CE6 A;  1CHM A;  1O0X A;  2GG2 A;  1R5G A;  2GG9 A;  4RZY A;  1C27 A;  4ZWO A;  2NQ6 A;  3PKE A;  3FM3 A;  2GU7 A;  2ADU A;  2EA4 A;  3TAV A;  2Q93 A;  4RGZ 1;  2GGB A;  1QXY A;  3IU7 A;  2GG7 A;  2P98 A;  1QZY A;  2BWS A;  4QR8 A;  3OOO A;  3L24 A;  4FLK A;  4IKT A;  4B28 A;  3L7G A;  2BWY A;  5CDE A;  2DFI A;  3IU9 A;  4FKC A;  2MAT A;  1XGM A;  2GGC A;  1BOA A;  2GZ5 A;  1WN1 A;  2GU6 A;  1R58 A;  3OVK A;  4S2R P;  1C22 A;  1JAW A;  1W7V A;  1QXZ A;  4Z7M A;  3PEB A;  4R60 A;  2V3X A;  1WL6 A;  4U6C A;  1YW8 A;  4IDY A;  3IU8 A;  3D27 A;  3QOC A;  2GG5 A;  5CDL A;  1Y1N A;  1XGS A;  2G6P A;  5JI6 A;  1YJ3 A;  4FLJ A;  3PN9 A;  1N51 A;  3PKD A;  4U6Z A;  5JHU A;  1YW9 A;  1WY2 A;  3Q6D A;  1YW7 A;  3RVA A;  2B3K A;  2EVM A;  3CB6 A;  1XGN A;  3PKC A;  2BWT A;  1YVM A;  4IKU A;  4U70 A;  4RZZ A;  2Q92 A;  5D6E A;  2BWX A;  4MAT A;  2HOW A;  3BIT A;  2EVO A;  2GG3 A;  4JUQ A;  3BIQ A;  1R5H A;  2Q94 A;  4U75 A;  1W2M A;  3FMQ A;  2Q8K A;  3CB5 A;  2Q96 A;  2NQ7 A;  5FCF A;  4S01 A;  4ZWU A;  4IU6 A;  4U6J A;  5FCH A;  3PKB A;  1QXW A;  4IPA A;  2Q95 A;  1M35 A;  5CIK A;  4U69 A;  4ZNG A;  4OOK A;  4PV4 A;  2GA2 A;  2BN7 A;  1PV9 A;  4S00 A;  3ROR A;  3CTZ A;  2BH3 A;  4A6W A;  1BN5 A;  4U76 A;  1KQ0 A;  2BHC A;  5E2C A;  4U1B A;  1B59 A;  3I7M A;  4U6W A;  4PNC A;  2GG0 A;  1WL9 A;  5D6F A;  1WLR A;  2OKN A;  1WBQ A;  4IKR A;  1A16 A;  4U71 A;  2ZSG A;  4HXX A;  4U73 A;  5JFR A;  2IW2 A;  1KP0 A;  4EGE A;  3FMR A;  4FLI A;  4U6E A;  4A6V A;  2B3H A;  4IEC A;  3S6B A;  1C21 A;  3MR1 A;  3BIP A;  1C23 A;  2GTX A;  4IF7 A;  2BWW A;  4FO8 A;  2B3L A;  2GU5 A;  5E5B A;  1B6A A;  3MAT A;  1C24 A;  4IKS A;  1XNZ A;  2EA2 A;  3O5V A;  2BHA A;  2BB7 A;  2P9A A;  5CDV A;  4S2T P;  3TB5 A;  2EVC A;  4FO7 A;  1XGO A;  4ZWP A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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