1WY2A

Crystal structure of the prolidase from pyrococcus horikoshii ot3
Total Genus 126
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
126
sequence length
351
structure length
351
Chain Sequence
MDIMNEKVKKIIEFMDKNSIDAVLIAKNPNVYYISGASPLAGGYILITGESATLYVPELEYEMAKEESNIPVEKFKKMDEFYKALEGIKSLGIESSLPYGFIEELKKKANIKEFKKVDDVIRDMRIIKSEKEIKIIEKACEIADKAVMAAIEEITEGKKEREVAAKVEYLMKMNGAEKPAFDTIIASGYRSALPHGVASDKRIERGDLVVIDLGALYQHYNSDITRTIVVGSPNEKQKEIYEIVLEAQKKAVESAKPGITAKELDSIARNIIAEYGYGEYFNHSLGHGVGLEVHEWPRVSQYDETVLREGMVITIEPGIYIPKIGGVRIEDTILITKNGSKRLTKTERELI
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Xaa-Pro dipeptidase
publication title Crystal Structure of the Prolidase from Pyrococcus horikoshii OT3
rcsb
source organism Pyrococcus horikoshii
total genus 126
structure length 351
sequence length 351
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2005-02-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1wy2A01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1wy2A02
1JAWA 2EA4A 2ZSGA 2BB7A 1MATA 4ZNGA 5E5BA 2GU6A 1CHMA 3MX6A 4FLIA 1O0XA 3CB6A 1WLRA 5CIKA 1C22A 4FO7A 2P98A 4RGZ1 2P9AA 1WL6A 2BWUA 1KP0A 3BIQA 3L24A 2HOWA 2GG2A 2GG0A 4U70A 3CB5A 2GU4A 2GZ5A 3S6BA 2GG8A 3PKEA 2V3ZA 2V3XA 3OOOA 3RORA 5CE6A 4IKUA 2Q93A 4FLJA 4A6VA 1R5HA 3MATA 2BWVA 2GGCA 1QZYA 2B3KA 3PKBA 4OOKA 4U6JA 1B6AA 1C27A 3PEBA 2GG9A 4B28A 1PV9A 3FMRA 4IKRA 1W2MA 5CLSA 2GG5A 1XGSA 2GA2A 4IECA 4JUQA 1C23A 3QOCA 4PV4A 2BHBA 1WY2A 2EVCA 3BIPA 4ZWUA 1XGOA 3TAVA 3PKAA 1XNZA 5E2CA 3FMQA 1YW9A 3I7MA 2BHCA 2Q94A 1KQ9A 4FLLA 3Q6DA 2GU7A 4ZWOA 3O5VA 3CTZA 2BWWA 4FUKA 2NQ6A 2OAZA 2MATA 2Q95A 4U6CA 4U6WA 5CNXA 4HXXA 2BHAA 1R5GA 1WL9A 2GG7A 5FCFA 2DFIA 4R60A 5CDEA 2P99A 3PKDA 4U76A 5JFRA 4FLKA 1BOAA 4U71A 2BWTA 1QXZA 2B3HA 3IU7A 2GTXA 1B59A 2G6PA 1A16A 2BWYA 3OVKA 2BH3A 3IL0A 3PN9A 3IU9A 4PNCA 2EVOA 4MATA 5FCHA 4U69A 2OKNA 1BN5A 2BWSA 4FO8A 2NQ7A 1WN1A 4S01A 2V6CA 4U73A 2Q8KA 2BHDA 2EVMA 4IPAA 4U6ZA 4QR8A 3IG4A 1R58A 3IU8A 5JHUA 1W7VA 2Q92A 1C24A 4U75A 1QXWA 3TB5A 1N51A 2IW2A 2B3LA 4Z7MA 4RZZA 1M35A 4IF7A 1KQ0A 4U1BA 2BN7A 4EGEA 1WBQA 1XGMA 4KM3A 3MR1A 3FM3A 1C21A 2ADUA 3L7GA 5CDLA 4IKSA 1Y1NA 3PKCA 4S2TP 1QXYA 2GGBA 2GU5A 2GG3A 4IKTA 4ZWPA 3BITA 1YJ3A 4S2RP 3RVAA 3D27A 4U6EA 4IU6A 5D6EA 5JI6A 5CDVA 1XGNA 4A6WA 4RZYA 1WKMA 2BWXA 1YW8A 4IDYA 5D6FA 4S00A 2EA2A 2Q96A 4FKCA 2V3YA 1YW7A 1YVMA
chains in the Genus database with same CATH superfamily
1JAWA 2EA4A 2ZSGA 2BB7A 1MATA 4ZNGA 5E5BA 2GU6A 1CHMA 3MX6A 4FLIA 1O0XA 3CB6A 1WLRA 5CIKA 1C22A 4FO7A 2P98A 4RGZ1 2P9AA 1WL6A 2BWUA 1KP0A 3BIQA 3L24A 2HOWA 2GG2A 2GG0A 4U70A 3CB5A 2GU4A 2GZ5A 3S6BA 2GG8A 3PKEA 2V3ZA 2V3XA 3OOOA 3RORA 5CE6A 4IKUA 2Q93A 4FLJA 4A6VA 1R5HA 3MATA 2BWVA 2GGCA 1QZYA 2B3KA 3PKBA 4OOKA 4U6JA 1B6AA 1C27A 3PEBA 2GG9A 4B28A 1PV9A 3FMRA 4IKRA 1W2MA 5CLSA 2GG5A 1XGSA 2GA2A 4IECA 4JUQA 1C23A 3QOCA 4PV4A 2BHBA 1WY2A 2EVCA 3BIPA 4ZWUA 1XGOA 3TAVA 3PKAA 1XNZA 5E2CA 3FMQA 1YW9A 3I7MA 2BHCA 2Q94A 1KQ9A 4FLLA 3Q6DA 2GU7A 4ZWOA 3O5VA 3CTZA 2BWWA 4FUKA 2NQ6A 2OAZA 2MATA 2Q95A 4U6CA 4U6WA 5CNXA 4HXXA 2BHAA 1R5GA 1WL9A 2GG7A 5FCFA 2DFIA 4R60A 5CDEA 2P99A 3PKDA 4U76A 5JFRA 4FLKA 1BOAA 4U71A 2BWTA 1QXZA 2B3HA 3IU7A 2GTXA 1B59A 2G6PA 1A16A 2BWYA 3OVKA 2BH3A 3IL0A 3PN9A 3IU9A 4PNCA 2EVOA 4MATA 5FCHA 4U69A 2OKNA 1BN5A 2BWSA 4FO8A 2NQ7A 1WN1A 4S01A 2V6CA 4U73A 2Q8KA 2BHDA 2EVMA 4IPAA 4U6ZA 4QR8A 3IG4A 1R58A 3IU8A 5JHUA 1W7VA 2Q92A 1C24A 4U75A 1QXWA 3TB5A 1N51A 2IW2A 2B3LA 4Z7MA 4RZZA 1M35A 4IF7A 1KQ0A 4U1BA 2BN7A 4EGEA 1WBQA 1XGMA 4KM3A 3MR1A 3FM3A 1C21A 2ADUA 3L7GA 5CDLA 4IKSA 1Y1NA 3PKCA 4S2TP 1QXYA 2GGBA 2GU5A 2GG3A 4IKTA 4ZWPA 3BITA 1YJ3A 4S2RP 3RVAA 3D27A 4U6EA 4IU6A 5D6EA 5JI6A 5CDVA 1XGNA 4A6WA 4RZYA 1WKMA 2BWXA 1YW8A 4IDYA 5D6FA 4S00A 2EA2A 2Q96A 4FKCA 2V3YA 1YW7A 1YVMA
chains in the Genus database with same CATH topology
1JAWA 2EA4A 2ZSGA 2BB7A 1MATA 4ZNGA 5E5BA 2GU6A 1CHMA 3MX6A 4FLIA 1O0XA 3CB6A 1WLRA 5CIKA 1C22A 4FO7A 2P98A 4RGZ1 2P9AA 1WL6A 2BWUA 1KP0A 3BIQA 3L24A 2HOWA 2GG2A 2GG0A 4U70A 3CB5A 2GU4A 2GZ5A 3S6BA 2GG8A 3PKEA 2V3ZA 2V3XA 3OOOA 3RORA 5CE6A 4IKUA 2Q93A 4FLJA 4A6VA 1R5HA 3MATA 2BWVA 2GGCA 1QZYA 2B3KA 3PKBA 4OOKA 4U6JA 1B6AA 1C27A 3PEBA 2GG9A 4B28A 1PV9A 3FMRA 4IKRA 1W2MA 5CLSA 2GG5A 1XGSA 2GA2A 4IECA 4JUQA 1C23A 3QOCA 4PV4A 2BHBA 1WY2A 2EVCA 3BIPA 4ZWUA 1XGOA 3TAVA 3PKAA 1XNZA 5E2CA 3FMQA 1YW9A 3I7MA 2BHCA 2Q94A 1KQ9A 4FLLA 3Q6DA 2GU7A 4ZWOA 3O5VA 3CTZA 2BWWA 4FUKA 2NQ6A 2OAZA 2MATA 2Q95A 4U6CA 4U6WA 5CNXA 4HXXA 2BHAA 1R5GA 1WL9A 2GG7A 5FCFA 2DFIA 4R60A 5CDEA 2P99A 3PKDA 4U76A 5JFRA 4FLKA 1BOAA 4U71A 2BWTA 1QXZA 2B3HA 3IU7A 2GTXA 1B59A 2G6PA 1A16A 2BWYA 3OVKA 2BH3A 3IL0A 3PN9A 3IU9A 4PNCA 2EVOA 4MATA 5FCHA 4U69A 2OKNA 1BN5A 2BWSA 4FO8A 2NQ7A 1WN1A 4S01A 2V6CA 4U73A 2Q8KA 2BHDA 2EVMA 4IPAA 4U6ZA 4QR8A 3IG4A 1R58A 3IU8A 5JHUA 1W7VA 2Q92A 1C24A 4U75A 1QXWA 3TB5A 1N51A 2IW2A 2B3LA 4Z7MA 4RZZA 1M35A 4IF7A 1KQ0A 4U1BA 2BN7A 4EGEA 1WBQA 1XGMA 4KM3A 3MR1A 3FM3A 1C21A 2ADUA 3L7GA 5CDLA 4IKSA 1Y1NA 3PKCA 4S2TP 1QXYA 2GGBA 2GU5A 2GG3A 4IKTA 4ZWPA 3BITA 1YJ3A 4S2RP 3RVAA 3D27A 4U6EA 4IU6A 5D6EA 5JI6A 5CDVA 1XGNA 4A6WA 4RZYA 1WKMA 2BWXA 1YW8A 4IDYA 5D6FA 4S00A 2EA2A 2Q96A 4FKCA 2V3YA 1YW7A 1YVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1JAW A;  2EA4 A;  2ZSG A;  2BB7 A;  1MAT A;  4ZNG A;  5E5B A;  2GU6 A;  1CHM A;  3MX6 A;  4FLI A;  1O0X A;  3CB6 A;  1WLR A;  5CIK A;  1C22 A;  4FO7 A;  2P98 A;  4RGZ 1;  2P9A A;  1WL6 A;  2BWU A;  1KP0 A;  3BIQ A;  3L24 A;  2HOW A;  2GG2 A;  2GG0 A;  4U70 A;  3CB5 A;  2GU4 A;  2GZ5 A;  3S6B A;  2GG8 A;  3PKE A;  2V3Z A;  2V3X A;  3OOO A;  3ROR A;  5CE6 A;  4IKU A;  2Q93 A;  4FLJ A;  4A6V A;  1R5H A;  3MAT A;  2BWV A;  2GGC A;  1QZY A;  2B3K A;  3PKB A;  4OOK A;  4U6J A;  1B6A A;  1C27 A;  3PEB A;  2GG9 A;  4B28 A;  1PV9 A;  3FMR A;  4IKR A;  1W2M A;  5CLS A;  2GG5 A;  1XGS A;  2GA2 A;  4IEC A;  4JUQ A;  1C23 A;  3QOC A;  4PV4 A;  2BHB A;  1WY2 A;  2EVC A;  3BIP A;  4ZWU A;  1XGO A;  3TAV A;  3PKA A;  1XNZ A;  5E2C A;  3FMQ A;  1YW9 A;  3I7M A;  2BHC A;  2Q94 A;  1KQ9 A;  4FLL A;  3Q6D A;  2GU7 A;  4ZWO A;  3O5V A;  3CTZ A;  2BWW A;  4FUK A;  2NQ6 A;  2OAZ A;  2MAT A;  2Q95 A;  4U6C A;  4U6W A;  5CNX A;  4HXX A;  2BHA A;  1R5G A;  1WL9 A;  2GG7 A;  5FCF A;  2DFI A;  4R60 A;  5CDE A;  2P99 A;  3PKD A;  4U76 A;  5JFR A;  4FLK A;  1BOA A;  4U71 A;  2BWT A;  1QXZ A;  2B3H A;  3IU7 A;  2GTX A;  1B59 A;  2G6P A;  1A16 A;  2BWY A;  3OVK A;  2BH3 A;  3IL0 A;  3PN9 A;  3IU9 A;  4PNC A;  2EVO A;  4MAT A;  5FCH A;  4U69 A;  2OKN A;  1BN5 A;  2BWS A;  4FO8 A;  2NQ7 A;  1WN1 A;  4S01 A;  2V6C A;  4U73 A;  2Q8K A;  2BHD A;  2EVM A;  4IPA A;  4U6Z A;  4QR8 A;  3IG4 A;  1R58 A;  3IU8 A;  5JHU A;  1W7V A;  2Q92 A;  1C24 A;  4U75 A;  1QXW A;  3TB5 A;  1N51 A;  2IW2 A;  2B3L A;  4Z7M A;  4RZZ A;  1M35 A;  4IF7 A;  1KQ0 A;  4U1B A;  2BN7 A;  4EGE A;  1WBQ A;  1XGM A;  4KM3 A;  3MR1 A;  3FM3 A;  1C21 A;  2ADU A;  3L7G A;  5CDL A;  4IKS A;  1Y1N A;  3PKC A;  4S2T P;  1QXY A;  2GGB A;  2GU5 A;  2GG3 A;  4IKT A;  4ZWP A;  3BIT A;  1YJ3 A;  4S2R P;  3RVA A;  3D27 A;  4U6E A;  4IU6 A;  5D6E A;  5JI6 A;  5CDV A;  1XGN A;  4A6W A;  4RZY A;  1WKM A;  2BWX A;  1YW8 A;  4IDY A;  5D6F A;  4S00 A;  2EA2 A;  2Q96 A;  4FKC A;  2V3Y A;  1YW7 A;  1YVM A; 
#chains in the Genus database with same CATH topology
 1JAW A;  2EA4 A;  2ZSG A;  2BB7 A;  1MAT A;  4ZNG A;  5E5B A;  2GU6 A;  1CHM A;  3MX6 A;  4FLI A;  1O0X A;  3CB6 A;  1WLR A;  5CIK A;  1C22 A;  4FO7 A;  2P98 A;  4RGZ 1;  2P9A A;  1WL6 A;  2BWU A;  1KP0 A;  3BIQ A;  3L24 A;  2HOW A;  2GG2 A;  2GG0 A;  4U70 A;  3CB5 A;  2GU4 A;  2GZ5 A;  3S6B A;  2GG8 A;  3PKE A;  2V3Z A;  2V3X A;  3OOO A;  3ROR A;  5CE6 A;  4IKU A;  2Q93 A;  4FLJ A;  4A6V A;  1R5H A;  3MAT A;  2BWV A;  2GGC A;  1QZY A;  2B3K A;  3PKB A;  4OOK A;  4U6J A;  1B6A A;  1C27 A;  3PEB A;  2GG9 A;  4B28 A;  1PV9 A;  3FMR A;  4IKR A;  1W2M A;  5CLS A;  2GG5 A;  1XGS A;  2GA2 A;  4IEC A;  4JUQ A;  1C23 A;  3QOC A;  4PV4 A;  2BHB A;  1WY2 A;  2EVC A;  3BIP A;  4ZWU A;  1XGO A;  3TAV A;  3PKA A;  1XNZ A;  5E2C A;  3FMQ A;  1YW9 A;  3I7M A;  2BHC A;  2Q94 A;  1KQ9 A;  4FLL A;  3Q6D A;  2GU7 A;  4ZWO A;  3O5V A;  3CTZ A;  2BWW A;  4FUK A;  2NQ6 A;  2OAZ A;  2MAT A;  2Q95 A;  4U6C A;  4U6W A;  5CNX A;  4HXX A;  2BHA A;  1R5G A;  1WL9 A;  2GG7 A;  5FCF A;  2DFI A;  4R60 A;  5CDE A;  2P99 A;  3PKD A;  4U76 A;  5JFR A;  4FLK A;  1BOA A;  4U71 A;  2BWT A;  1QXZ A;  2B3H A;  3IU7 A;  2GTX A;  1B59 A;  2G6P A;  1A16 A;  2BWY A;  3OVK A;  2BH3 A;  3IL0 A;  3PN9 A;  3IU9 A;  4PNC A;  2EVO A;  4MAT A;  5FCH A;  4U69 A;  2OKN A;  1BN5 A;  2BWS A;  4FO8 A;  2NQ7 A;  1WN1 A;  4S01 A;  2V6C A;  4U73 A;  2Q8K A;  2BHD A;  2EVM A;  4IPA A;  4U6Z A;  4QR8 A;  3IG4 A;  1R58 A;  3IU8 A;  5JHU A;  1W7V A;  2Q92 A;  1C24 A;  4U75 A;  1QXW A;  3TB5 A;  1N51 A;  2IW2 A;  2B3L A;  4Z7M A;  4RZZ A;  1M35 A;  4IF7 A;  1KQ0 A;  4U1B A;  2BN7 A;  4EGE A;  1WBQ A;  1XGM A;  4KM3 A;  3MR1 A;  3FM3 A;  1C21 A;  2ADU A;  3L7G A;  5CDL A;  4IKS A;  1Y1N A;  3PKC A;  4S2T P;  1QXY A;  2GGB A;  2GU5 A;  2GG3 A;  4IKT A;  4ZWP A;  3BIT A;  1YJ3 A;  4S2R P;  3RVA A;  3D27 A;  4U6E A;  4IU6 A;  5D6E A;  5JI6 A;  5CDV A;  1XGN A;  4A6W A;  4RZY A;  1WKM A;  2BWX A;  1YW8 A;  4IDY A;  5D6F A;  4S00 A;  2EA2 A;  2Q96 A;  4FKC A;  2V3Y A;  1YW7 A;  1YVM A; 
#chains in the Genus database with same CATH homology
 1JAW A;  2EA4 A;  2ZSG A;  2BB7 A;  1MAT A;  4ZNG A;  5E5B A;  2GU6 A;  1CHM A;  3MX6 A;  4FLI A;  1O0X A;  3CB6 A;  1WLR A;  5CIK A;  1C22 A;  4FO7 A;  2P98 A;  4RGZ 1;  2P9A A;  1WL6 A;  2BWU A;  1KP0 A;  3BIQ A;  3L24 A;  2HOW A;  2GG2 A;  2GG0 A;  4U70 A;  3CB5 A;  2GU4 A;  2GZ5 A;  3S6B A;  2GG8 A;  3PKE A;  2V3Z A;  2V3X A;  3OOO A;  3ROR A;  5CE6 A;  4IKU A;  2Q93 A;  4FLJ A;  4A6V A;  1R5H A;  3MAT A;  2BWV A;  2GGC A;  1QZY A;  2B3K A;  3PKB A;  4OOK A;  4U6J A;  1B6A A;  1C27 A;  3PEB A;  2GG9 A;  4B28 A;  1PV9 A;  3FMR A;  4IKR A;  1W2M A;  5CLS A;  2GG5 A;  1XGS A;  2GA2 A;  4IEC A;  4JUQ A;  1C23 A;  3QOC A;  4PV4 A;  2BHB A;  1WY2 A;  2EVC A;  3BIP A;  4ZWU A;  1XGO A;  3TAV A;  3PKA A;  1XNZ A;  5E2C A;  3FMQ A;  1YW9 A;  3I7M A;  2BHC A;  2Q94 A;  1KQ9 A;  4FLL A;  3Q6D A;  2GU7 A;  4ZWO A;  3O5V A;  3CTZ A;  2BWW A;  4FUK A;  2NQ6 A;  2OAZ A;  2MAT A;  2Q95 A;  4U6C A;  4U6W A;  5CNX A;  4HXX A;  2BHA A;  1R5G A;  1WL9 A;  2GG7 A;  5FCF A;  2DFI A;  4R60 A;  5CDE A;  2P99 A;  3PKD A;  4U76 A;  5JFR A;  4FLK A;  1BOA A;  4U71 A;  2BWT A;  1QXZ A;  2B3H A;  3IU7 A;  2GTX A;  1B59 A;  2G6P A;  1A16 A;  2BWY A;  3OVK A;  2BH3 A;  3IL0 A;  3PN9 A;  3IU9 A;  4PNC A;  2EVO A;  4MAT A;  5FCH A;  4U69 A;  2OKN A;  1BN5 A;  2BWS A;  4FO8 A;  2NQ7 A;  1WN1 A;  4S01 A;  2V6C A;  4U73 A;  2Q8K A;  2BHD A;  2EVM A;  4IPA A;  4U6Z A;  4QR8 A;  3IG4 A;  1R58 A;  3IU8 A;  5JHU A;  1W7V A;  2Q92 A;  1C24 A;  4U75 A;  1QXW A;  3TB5 A;  1N51 A;  2IW2 A;  2B3L A;  4Z7M A;  4RZZ A;  1M35 A;  4IF7 A;  1KQ0 A;  4U1B A;  2BN7 A;  4EGE A;  1WBQ A;  1XGM A;  4KM3 A;  3MR1 A;  3FM3 A;  1C21 A;  2ADU A;  3L7G A;  5CDL A;  4IKS A;  1Y1N A;  3PKC A;  4S2T P;  1QXY A;  2GGB A;  2GU5 A;  2GG3 A;  4IKT A;  4ZWP A;  3BIT A;  1YJ3 A;  4S2R P;  3RVA A;  3D27 A;  4U6E A;  4IU6 A;  5D6E A;  5JI6 A;  5CDV A;  1XGN A;  4A6W A;  4RZY A;  1WKM A;  2BWX A;  1YW8 A;  4IDY A;  5D6F A;  4S00 A;  2EA2 A;  2Q96 A;  4FKC A;  2V3Y A;  1YW7 A;  1YVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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