1JAWA

Aminopeptidase p from e. coli low ph form
Total Genus 151
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
151
sequence length
440
structure length
440
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWYGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure and mechanism of a proline-specific aminopeptidase from Escherichia coli.
pubmed doi rcsb
molecule tags Proline peptidase
molecule keywords AMINOPEPTIDASE P
total genus 151
structure length 440
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 1997-12-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 1jawA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1jawA02
1QXYA 3PKAA 1KQ9A 1B6AA 4FLIA 2BH3A 2GGBA 4ZWPA 1C23A 1R5HA 2GU5A 2P9AA 4FO8A 1WBQA 4IKRA 2GGCA 5CE6A 3PN9A 5E5BA 2GG8A 1WL9A 4U69A 2ADUA 4FO7A 2BB7A 2GG0A 2NQ6A 5JFRA 5D6EA 2BHCA 1CHMA 2Q95A 4U1BA 1XNZA 4ZWOA 2Q92A 2HOWA 1BOAA 1W7VA 2GG9A 3S6BA 5FCFA 2BN7A 2OAZA 2B3KA 3IU8A 1N51A 5FCHA 1QXWA 4R60A 2EA2A 1XGNA 2EA4A 2GU7A 1A16A 2V3YA 3IU9A 1R58A 5CLSA 2BHAA 3BITA 1W2MA 5CNXA 4IPAA 3FMRA 1C24A 3FMQA 2P99A 4IU6A 4U76A 3QOCA 3IG4A 1QZYA 3TB5A 2G6PA 2DFIA 3CTZA 3O5VA 3PEBA 1C22A 1R5GA 5D6FA 4ZNGA 3MX6A 3I7MA 4IKUA 4U71A 2BWUA 4U6WA 4S2TP 5JI6A 2BWXA 1XGOA 2GU6A 1QXZA 4MATA 5CIKA 4S2RP 2BWWA 1JAWA 2P98A 4U6CA 4U6ZA 2BHDA 1C21A 3Q6DA 4PV4A 2MATA 2Q93A 4RGZ1 4A6WA 1WLRA 2GG3A 3IL0A 2GG7A 4PNCA 3BIPA 1C27A 3PKBA 3CB5A 4FUKA 4B28A 1WL6A 1WN1A 1PV9A 2V6CA 2BHBA 4U6EA 3BIQA 4RZYA 4QR8A 4IDYA 2BWYA 1BN5A 2EVMA 3MR1A 4KM3A 1YW8A 2NQ7A 1Y1NA 1KP0A 1M35A 2B3LA 3L7GA 2V3XA 4JUQA 4A6VA 2GA2A 3RORA 5JHUA 1O0XA 2Q96A 4FLLA 2OKNA 2GG5A 3MATA 2BWTA 4ZWUA 4OOKA 2GTXA 3PKEA 3IU7A 4IECA 3PKCA 3PKDA 4IKSA 4FKCA 1YW7A 2GU4A 2GZ5A 4FLJA 4U70A 1XGSA 3OOOA 2EVOA 3FM3A 1XGMA 5E2CA 3L24A 3D27A 4S01A 5CDLA 4RZZA 2BWVA 2IW2A 1YVMA 4FLKA 5CDVA 2B3HA 1YW9A 2Q8KA 4Z7MA 2ZSGA 4HXXA 2V3ZA 4IKTA 4U75A 3CB6A 5CDEA 4EGEA 1YJ3A 4U6JA 1KQ0A 1WY2A 2BWSA 4S00A 3RVAA 1B59A 1WKMA 2GG2A 3OVKA 3TAVA 1MATA 2Q94A 4IF7A 4U73A 2EVCA
chains in the Genus database with same CATH superfamily
1QXYA 3PKAA 1KQ9A 1B6AA 4FLIA 2BH3A 2GGBA 4ZWPA 1C23A 1R5HA 2GU5A 2P9AA 4FO8A 1WBQA 4IKRA 2GGCA 5CE6A 3PN9A 5E5BA 2GG8A 1WL9A 4U69A 2ADUA 4FO7A 2BB7A 2GG0A 2NQ6A 5JFRA 5D6EA 2BHCA 1CHMA 2Q95A 4U1BA 1XNZA 4ZWOA 2Q92A 2HOWA 1BOAA 1W7VA 2GG9A 3S6BA 5FCFA 2BN7A 2OAZA 2B3KA 3IU8A 1N51A 5FCHA 1QXWA 4R60A 2EA2A 1XGNA 2EA4A 2GU7A 1A16A 2V3YA 3IU9A 1R58A 5CLSA 2BHAA 3BITA 1W2MA 5CNXA 4IPAA 3FMRA 1C24A 3FMQA 2P99A 4IU6A 4U76A 3QOCA 3IG4A 1QZYA 3TB5A 2G6PA 2DFIA 3CTZA 3O5VA 3PEBA 1C22A 1R5GA 5D6FA 4ZNGA 3MX6A 3I7MA 4IKUA 4U71A 2BWUA 4U6WA 4S2TP 5JI6A 2BWXA 1XGOA 2GU6A 1QXZA 4MATA 5CIKA 4S2RP 2BWWA 1JAWA 2P98A 4U6CA 4U6ZA 2BHDA 1C21A 3Q6DA 4PV4A 2MATA 2Q93A 4RGZ1 4A6WA 1WLRA 2GG3A 3IL0A 2GG7A 4PNCA 3BIPA 1C27A 3PKBA 3CB5A 4FUKA 4B28A 1WL6A 1WN1A 1PV9A 2V6CA 2BHBA 4U6EA 3BIQA 4RZYA 4QR8A 4IDYA 2BWYA 1BN5A 2EVMA 3MR1A 4KM3A 1YW8A 2NQ7A 1Y1NA 1KP0A 1M35A 2B3LA 3L7GA 2V3XA 4JUQA 4A6VA 2GA2A 3RORA 5JHUA 1O0XA 2Q96A 4FLLA 2OKNA 2GG5A 3MATA 2BWTA 4ZWUA 4OOKA 2GTXA 3PKEA 3IU7A 4IECA 3PKCA 3PKDA 4IKSA 4FKCA 1YW7A 2GU4A 2GZ5A 4FLJA 4U70A 1XGSA 3OOOA 2EVOA 3FM3A 1XGMA 5E2CA 3L24A 3D27A 4S01A 5CDLA 4RZZA 2BWVA 2IW2A 1YVMA 4FLKA 5CDVA 2B3HA 1YW9A 2Q8KA 4Z7MA 2ZSGA 4HXXA 2V3ZA 4IKTA 4U75A 3CB6A 5CDEA 4EGEA 1YJ3A 4U6JA 1KQ0A 1WY2A 2BWSA 4S00A 3RVAA 1B59A 1WKMA 2GG2A 3OVKA 3TAVA 1MATA 2Q94A 4IF7A 4U73A 2EVCA
chains in the Genus database with same CATH topology
1QXYA 3PKAA 1KQ9A 1B6AA 4FLIA 2BH3A 2GGBA 4ZWPA 1C23A 1R5HA 2GU5A 2P9AA 4FO8A 1WBQA 4IKRA 2GGCA 5CE6A 3PN9A 5E5BA 2GG8A 1WL9A 4U69A 2ADUA 4FO7A 2BB7A 2GG0A 2NQ6A 5JFRA 5D6EA 2BHCA 1CHMA 2Q95A 4U1BA 1XNZA 4ZWOA 2Q92A 2HOWA 1BOAA 1W7VA 2GG9A 3S6BA 5FCFA 2BN7A 2OAZA 2B3KA 3IU8A 1N51A 5FCHA 1QXWA 4R60A 2EA2A 1XGNA 2EA4A 2GU7A 1A16A 2V3YA 3IU9A 1R58A 5CLSA 2BHAA 3BITA 1W2MA 5CNXA 4IPAA 3FMRA 1C24A 3FMQA 2P99A 4IU6A 4U76A 3QOCA 3IG4A 1QZYA 3TB5A 2G6PA 2DFIA 3CTZA 3O5VA 3PEBA 1C22A 1R5GA 5D6FA 4ZNGA 3MX6A 3I7MA 4IKUA 4U71A 2BWUA 4U6WA 4S2TP 5JI6A 2BWXA 1XGOA 2GU6A 1QXZA 4MATA 5CIKA 4S2RP 2BWWA 1JAWA 2P98A 4U6CA 4U6ZA 2BHDA 1C21A 3Q6DA 4PV4A 2MATA 2Q93A 4RGZ1 4A6WA 1WLRA 2GG3A 3IL0A 2GG7A 4PNCA 3BIPA 1C27A 3PKBA 3CB5A 4FUKA 4B28A 1WL6A 1WN1A 1PV9A 2V6CA 2BHBA 4U6EA 3BIQA 4RZYA 4QR8A 4IDYA 2BWYA 1BN5A 2EVMA 3MR1A 4KM3A 1YW8A 2NQ7A 1Y1NA 1KP0A 1M35A 2B3LA 3L7GA 2V3XA 4JUQA 4A6VA 2GA2A 3RORA 5JHUA 1O0XA 2Q96A 4FLLA 2OKNA 2GG5A 3MATA 2BWTA 4ZWUA 4OOKA 2GTXA 3PKEA 3IU7A 4IECA 3PKCA 3PKDA 4IKSA 4FKCA 1YW7A 2GU4A 2GZ5A 4FLJA 4U70A 1XGSA 3OOOA 2EVOA 3FM3A 1XGMA 5E2CA 3L24A 3D27A 4S01A 5CDLA 4RZZA 2BWVA 2IW2A 1YVMA 4FLKA 5CDVA 2B3HA 1YW9A 2Q8KA 4Z7MA 2ZSGA 4HXXA 2V3ZA 4IKTA 4U75A 3CB6A 5CDEA 4EGEA 1YJ3A 4U6JA 1KQ0A 1WY2A 2BWSA 4S00A 3RVAA 1B59A 1WKMA 2GG2A 3OVKA 3TAVA 1MATA 2Q94A 4IF7A 4U73A 2EVCA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QXY A;  3PKA A;  1KQ9 A;  1B6A A;  4FLI A;  2BH3 A;  2GGB A;  4ZWP A;  1C23 A;  1R5H A;  2GU5 A;  2P9A A;  4FO8 A;  1WBQ A;  4IKR A;  2GGC A;  5CE6 A;  3PN9 A;  5E5B A;  2GG8 A;  1WL9 A;  4U69 A;  2ADU A;  4FO7 A;  2BB7 A;  2GG0 A;  2NQ6 A;  5JFR A;  5D6E A;  2BHC A;  1CHM A;  2Q95 A;  4U1B A;  1XNZ A;  4ZWO A;  2Q92 A;  2HOW A;  1BOA A;  1W7V A;  2GG9 A;  3S6B A;  5FCF A;  2BN7 A;  2OAZ A;  2B3K A;  3IU8 A;  1N51 A;  5FCH A;  1QXW A;  4R60 A;  2EA2 A;  1XGN A;  2EA4 A;  2GU7 A;  1A16 A;  2V3Y A;  3IU9 A;  1R58 A;  5CLS A;  2BHA A;  3BIT A;  1W2M A;  5CNX A;  4IPA A;  3FMR A;  1C24 A;  3FMQ A;  2P99 A;  4IU6 A;  4U76 A;  3QOC A;  3IG4 A;  1QZY A;  3TB5 A;  2G6P A;  2DFI A;  3CTZ A;  3O5V A;  3PEB A;  1C22 A;  1R5G A;  5D6F A;  4ZNG A;  3MX6 A;  3I7M A;  4IKU A;  4U71 A;  2BWU A;  4U6W A;  4S2T P;  5JI6 A;  2BWX A;  1XGO A;  2GU6 A;  1QXZ A;  4MAT A;  5CIK A;  4S2R P;  2BWW A;  1JAW A;  2P98 A;  4U6C A;  4U6Z A;  2BHD A;  1C21 A;  3Q6D A;  4PV4 A;  2MAT A;  2Q93 A;  4RGZ 1;  4A6W A;  1WLR A;  2GG3 A;  3IL0 A;  2GG7 A;  4PNC A;  3BIP A;  1C27 A;  3PKB A;  3CB5 A;  4FUK A;  4B28 A;  1WL6 A;  1WN1 A;  1PV9 A;  2V6C A;  2BHB A;  4U6E A;  3BIQ A;  4RZY A;  4QR8 A;  4IDY A;  2BWY A;  1BN5 A;  2EVM A;  3MR1 A;  4KM3 A;  1YW8 A;  2NQ7 A;  1Y1N A;  1KP0 A;  1M35 A;  2B3L A;  3L7G A;  2V3X A;  4JUQ A;  4A6V A;  2GA2 A;  3ROR A;  5JHU A;  1O0X A;  2Q96 A;  4FLL A;  2OKN A;  2GG5 A;  3MAT A;  2BWT A;  4ZWU A;  4OOK A;  2GTX A;  3PKE A;  3IU7 A;  4IEC A;  3PKC A;  3PKD A;  4IKS A;  4FKC A;  1YW7 A;  2GU4 A;  2GZ5 A;  4FLJ A;  4U70 A;  1XGS A;  3OOO A;  2EVO A;  3FM3 A;  1XGM A;  5E2C A;  3L24 A;  3D27 A;  4S01 A;  5CDL A;  4RZZ A;  2BWV A;  2IW2 A;  1YVM A;  4FLK A;  5CDV A;  2B3H A;  1YW9 A;  2Q8K A;  4Z7M A;  2ZSG A;  4HXX A;  2V3Z A;  4IKT A;  4U75 A;  3CB6 A;  5CDE A;  4EGE A;  1YJ3 A;  4U6J A;  1KQ0 A;  1WY2 A;  2BWS A;  4S00 A;  3RVA A;  1B59 A;  1WKM A;  2GG2 A;  3OVK A;  3TAV A;  1MAT A;  2Q94 A;  4IF7 A;  4U73 A;  2EVC A; 
#chains in the Genus database with same CATH topology
 1QXY A;  3PKA A;  1KQ9 A;  1B6A A;  4FLI A;  2BH3 A;  2GGB A;  4ZWP A;  1C23 A;  1R5H A;  2GU5 A;  2P9A A;  4FO8 A;  1WBQ A;  4IKR A;  2GGC A;  5CE6 A;  3PN9 A;  5E5B A;  2GG8 A;  1WL9 A;  4U69 A;  2ADU A;  4FO7 A;  2BB7 A;  2GG0 A;  2NQ6 A;  5JFR A;  5D6E A;  2BHC A;  1CHM A;  2Q95 A;  4U1B A;  1XNZ A;  4ZWO A;  2Q92 A;  2HOW A;  1BOA A;  1W7V A;  2GG9 A;  3S6B A;  5FCF A;  2BN7 A;  2OAZ A;  2B3K A;  3IU8 A;  1N51 A;  5FCH A;  1QXW A;  4R60 A;  2EA2 A;  1XGN A;  2EA4 A;  2GU7 A;  1A16 A;  2V3Y A;  3IU9 A;  1R58 A;  5CLS A;  2BHA A;  3BIT A;  1W2M A;  5CNX A;  4IPA A;  3FMR A;  1C24 A;  3FMQ A;  2P99 A;  4IU6 A;  4U76 A;  3QOC A;  3IG4 A;  1QZY A;  3TB5 A;  2G6P A;  2DFI A;  3CTZ A;  3O5V A;  3PEB A;  1C22 A;  1R5G A;  5D6F A;  4ZNG A;  3MX6 A;  3I7M A;  4IKU A;  4U71 A;  2BWU A;  4U6W A;  4S2T P;  5JI6 A;  2BWX A;  1XGO A;  2GU6 A;  1QXZ A;  4MAT A;  5CIK A;  4S2R P;  2BWW A;  1JAW A;  2P98 A;  4U6C A;  4U6Z A;  2BHD A;  1C21 A;  3Q6D A;  4PV4 A;  2MAT A;  2Q93 A;  4RGZ 1;  4A6W A;  1WLR A;  2GG3 A;  3IL0 A;  2GG7 A;  4PNC A;  3BIP A;  1C27 A;  3PKB A;  3CB5 A;  4FUK A;  4B28 A;  1WL6 A;  1WN1 A;  1PV9 A;  2V6C A;  2BHB A;  4U6E A;  3BIQ A;  4RZY A;  4QR8 A;  4IDY A;  2BWY A;  1BN5 A;  2EVM A;  3MR1 A;  4KM3 A;  1YW8 A;  2NQ7 A;  1Y1N A;  1KP0 A;  1M35 A;  2B3L A;  3L7G A;  2V3X A;  4JUQ A;  4A6V A;  2GA2 A;  3ROR A;  5JHU A;  1O0X A;  2Q96 A;  4FLL A;  2OKN A;  2GG5 A;  3MAT A;  2BWT A;  4ZWU A;  4OOK A;  2GTX A;  3PKE A;  3IU7 A;  4IEC A;  3PKC A;  3PKD A;  4IKS A;  4FKC A;  1YW7 A;  2GU4 A;  2GZ5 A;  4FLJ A;  4U70 A;  1XGS A;  3OOO A;  2EVO A;  3FM3 A;  1XGM A;  5E2C A;  3L24 A;  3D27 A;  4S01 A;  5CDL A;  4RZZ A;  2BWV A;  2IW2 A;  1YVM A;  4FLK A;  5CDV A;  2B3H A;  1YW9 A;  2Q8K A;  4Z7M A;  2ZSG A;  4HXX A;  2V3Z A;  4IKT A;  4U75 A;  3CB6 A;  5CDE A;  4EGE A;  1YJ3 A;  4U6J A;  1KQ0 A;  1WY2 A;  2BWS A;  4S00 A;  3RVA A;  1B59 A;  1WKM A;  2GG2 A;  3OVK A;  3TAV A;  1MAT A;  2Q94 A;  4IF7 A;  4U73 A;  2EVC A; 
#chains in the Genus database with same CATH homology
 1QXY A;  3PKA A;  1KQ9 A;  1B6A A;  4FLI A;  2BH3 A;  2GGB A;  4ZWP A;  1C23 A;  1R5H A;  2GU5 A;  2P9A A;  4FO8 A;  1WBQ A;  4IKR A;  2GGC A;  5CE6 A;  3PN9 A;  5E5B A;  2GG8 A;  1WL9 A;  4U69 A;  2ADU A;  4FO7 A;  2BB7 A;  2GG0 A;  2NQ6 A;  5JFR A;  5D6E A;  2BHC A;  1CHM A;  2Q95 A;  4U1B A;  1XNZ A;  4ZWO A;  2Q92 A;  2HOW A;  1BOA A;  1W7V A;  2GG9 A;  3S6B A;  5FCF A;  2BN7 A;  2OAZ A;  2B3K A;  3IU8 A;  1N51 A;  5FCH A;  1QXW A;  4R60 A;  2EA2 A;  1XGN A;  2EA4 A;  2GU7 A;  1A16 A;  2V3Y A;  3IU9 A;  1R58 A;  5CLS A;  2BHA A;  3BIT A;  1W2M A;  5CNX A;  4IPA A;  3FMR A;  1C24 A;  3FMQ A;  2P99 A;  4IU6 A;  4U76 A;  3QOC A;  3IG4 A;  1QZY A;  3TB5 A;  2G6P A;  2DFI A;  3CTZ A;  3O5V A;  3PEB A;  1C22 A;  1R5G A;  5D6F A;  4ZNG A;  3MX6 A;  3I7M A;  4IKU A;  4U71 A;  2BWU A;  4U6W A;  4S2T P;  5JI6 A;  2BWX A;  1XGO A;  2GU6 A;  1QXZ A;  4MAT A;  5CIK A;  4S2R P;  2BWW A;  1JAW A;  2P98 A;  4U6C A;  4U6Z A;  2BHD A;  1C21 A;  3Q6D A;  4PV4 A;  2MAT A;  2Q93 A;  4RGZ 1;  4A6W A;  1WLR A;  2GG3 A;  3IL0 A;  2GG7 A;  4PNC A;  3BIP A;  1C27 A;  3PKB A;  3CB5 A;  4FUK A;  4B28 A;  1WL6 A;  1WN1 A;  1PV9 A;  2V6C A;  2BHB A;  4U6E A;  3BIQ A;  4RZY A;  4QR8 A;  4IDY A;  2BWY A;  1BN5 A;  2EVM A;  3MR1 A;  4KM3 A;  1YW8 A;  2NQ7 A;  1Y1N A;  1KP0 A;  1M35 A;  2B3L A;  3L7G A;  2V3X A;  4JUQ A;  4A6V A;  2GA2 A;  3ROR A;  5JHU A;  1O0X A;  2Q96 A;  4FLL A;  2OKN A;  2GG5 A;  3MAT A;  2BWT A;  4ZWU A;  4OOK A;  2GTX A;  3PKE A;  3IU7 A;  4IEC A;  3PKC A;  3PKD A;  4IKS A;  4FKC A;  1YW7 A;  2GU4 A;  2GZ5 A;  4FLJ A;  4U70 A;  1XGS A;  3OOO A;  2EVO A;  3FM3 A;  1XGM A;  5E2C A;  3L24 A;  3D27 A;  4S01 A;  5CDL A;  4RZZ A;  2BWV A;  2IW2 A;  1YVM A;  4FLK A;  5CDV A;  2B3H A;  1YW9 A;  2Q8K A;  4Z7M A;  2ZSG A;  4HXX A;  2V3Z A;  4IKT A;  4U75 A;  3CB6 A;  5CDE A;  4EGE A;  1YJ3 A;  4U6J A;  1KQ0 A;  1WY2 A;  2BWS A;  4S00 A;  3RVA A;  1B59 A;  1WKM A;  2GG2 A;  3OVK A;  3TAV A;  1MAT A;  2Q94 A;  4IF7 A;  4U73 A;  2EVC A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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