4IF7A

Mycobacterium tuberculosis methionine aminopeptidase type 1c in complex with homocysteine-methyl disulfide
Total Genus 86
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
281
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase 2
publication title Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 281
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2012-12-14

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4if7A01
1QZYA 3IU8A 3MX6A 2EVOA 4U6CA 4IDYA 4FLIA 2ZSGA 3IU7A 5JI6A 1BOAA 5CIKA 2V3XA 1CHMA 4S01A 1C21A 4RZYA 1YW7A 1R58A 1YW8A 2G6PA 5E5BA 1YJ3A 2GG5A 4Z7MA 2NQ7A 1WL6A 2BWUA 3Q6DA 4RGZ1 3MR1A 1R5GA 4S2RP 1WLRA 3CTZA 3RORA 5D6EA 1R5HA 4IU6A 1XGSA 4U76A 1N51A 2OAZA 3MATA 2P99A 3IU9A 5CLSA 4ZWUA 3PKBA 4S2TP 1Y1NA 4U69A 4U73A 2BWWA 4FO8A 4A6VA 2Q96A 2BN7A 3BITA 4S00A 2GGBA 4U6JA 4R60A 4U6EA 2BHCA 1WL9A 2BWTA 2P9AA 1C24A 2Q92A 2GU6A 4ZWPA 1C23A 2B3KA 1JAWA 2V6CA 2V3YA 4FLLA 1WY2A 1C27A 2Q94A 3FMQA 4U70A 2IW2A 5CDVA 4IF7A 2GG9A 2BWVA 1QXZA 2BWSA 4U6WA 4EGEA 4U75A 2NQ6A 2Q8KA 2GZ5A 5CNXA 1M35A 1W2MA 2EA4A 2GG7A 3PKEA 2OKNA 2GA2A 1O0XA 1C22A 5FCFA 5CDLA 2V3ZA 2BB7A 4IKUA 3BIPA 1W7VA 2HOWA 4KM3A 4PNCA 4QR8A 2BHDA 2ADUA 2GG3A 3FM3A 4IECA 3FMRA 4IKTA 1XGNA 4MATA 2B3LA 4FO7A 4U6ZA 1WKMA 4HXXA 4FLKA 2BWYA 3RVAA 4FLJA 4ZWOA 1WBQA 1BN5A 4RZZA 4U1BA 1WN1A 1XGOA 2GG8A 1B59A 3BIQA 3L24A 2Q95A 1KQ9A 3L7GA 5FCHA 5JHUA 4PV4A 1QXYA 2GU4A 4OOKA 3IG4A 3TAVA 2EA2A 1KQ0A 4IKSA 5CE6A 1B6AA 1MATA 4JUQA 4ZNGA 3D27A 5JFRA 2B3HA 1YVMA 3TB5A 1XNZA 4FUKA 1YW9A 1A16A 2BHBA 4IKRA 4FKCA 2GG2A 2GU7A 2GG0A 2P98A 4U71A 3PKDA 3CB6A 2MATA 2GTXA 2GU5A 2GGCA 3S6BA 4B28A 1KP0A 1XGMA 5D6FA 3CB5A 2EVMA 2EVCA 3PKCA 5CDEA 2BWXA 1PV9A 1QXWA 4IPAA 2Q93A 2BH3A 2DFIA 3PKAA 2BHAA 4A6WA
chains in the Genus database with same CATH superfamily
1QZYA 3IU8A 3MX6A 2EVOA 4U6CA 4IDYA 4FLIA 2ZSGA 3IU7A 5JI6A 1BOAA 5CIKA 2V3XA 1CHMA 4S01A 1C21A 4RZYA 1YW7A 1R58A 1YW8A 2G6PA 5E5BA 1YJ3A 2GG5A 4Z7MA 2NQ7A 1WL6A 2BWUA 3Q6DA 4RGZ1 3MR1A 1R5GA 4S2RP 1WLRA 3CTZA 3RORA 5D6EA 1R5HA 4IU6A 1XGSA 4U76A 1N51A 2OAZA 3MATA 2P99A 3IU9A 5CLSA 4ZWUA 3PKBA 4S2TP 1Y1NA 4U69A 4U73A 2BWWA 4FO8A 4A6VA 2Q96A 2BN7A 3BITA 4S00A 2GGBA 4U6JA 4R60A 4U6EA 2BHCA 1WL9A 2BWTA 2P9AA 1C24A 2Q92A 2GU6A 4ZWPA 1C23A 2B3KA 1JAWA 2V6CA 2V3YA 4FLLA 1WY2A 1C27A 2Q94A 3FMQA 4U70A 2IW2A 5CDVA 4IF7A 2GG9A 2BWVA 1QXZA 2BWSA 4U6WA 4EGEA 4U75A 2NQ6A 2Q8KA 2GZ5A 5CNXA 1M35A 1W2MA 2EA4A 2GG7A 3PKEA 2OKNA 2GA2A 1O0XA 1C22A 5FCFA 5CDLA 2V3ZA 2BB7A 4IKUA 3BIPA 1W7VA 2HOWA 4KM3A 4PNCA 4QR8A 2BHDA 2ADUA 2GG3A 3FM3A 4IECA 3FMRA 4IKTA 1XGNA 4MATA 2B3LA 4FO7A 4U6ZA 1WKMA 4HXXA 4FLKA 2BWYA 3RVAA 4FLJA 4ZWOA 1WBQA 1BN5A 4RZZA 4U1BA 1WN1A 1XGOA 2GG8A 1B59A 3BIQA 3L24A 2Q95A 1KQ9A 3L7GA 5FCHA 5JHUA 4PV4A 1QXYA 2GU4A 4OOKA 3IG4A 3TAVA 2EA2A 1KQ0A 4IKSA 5CE6A 1B6AA 1MATA 4JUQA 4ZNGA 3D27A 5JFRA 2B3HA 1YVMA 3TB5A 1XNZA 4FUKA 1YW9A 1A16A 2BHBA 4IKRA 4FKCA 2GG2A 2GU7A 2GG0A 2P98A 4U71A 3PKDA 3CB6A 2MATA 2GTXA 2GU5A 2GGCA 3S6BA 4B28A 1KP0A 1XGMA 5D6FA 3CB5A 2EVMA 2EVCA 3PKCA 5CDEA 2BWXA 1PV9A 1QXWA 4IPAA 2Q93A 2BH3A 2DFIA 3PKAA 2BHAA 4A6WA
chains in the Genus database with same CATH topology
1QZYA 3IU8A 3MX6A 2EVOA 4U6CA 4IDYA 4FLIA 2ZSGA 3IU7A 5JI6A 1BOAA 5CIKA 2V3XA 1CHMA 4S01A 1C21A 4RZYA 1YW7A 1R58A 1YW8A 2G6PA 5E5BA 1YJ3A 2GG5A 4Z7MA 2NQ7A 1WL6A 2BWUA 3Q6DA 4RGZ1 3MR1A 1R5GA 4S2RP 1WLRA 3CTZA 3RORA 5D6EA 1R5HA 4IU6A 1XGSA 4U76A 1N51A 2OAZA 3MATA 2P99A 3IU9A 5CLSA 4ZWUA 3PKBA 4S2TP 1Y1NA 4U69A 4U73A 2BWWA 4FO8A 4A6VA 2Q96A 2BN7A 3BITA 4S00A 2GGBA 4U6JA 4R60A 4U6EA 2BHCA 1WL9A 2BWTA 2P9AA 1C24A 2Q92A 2GU6A 4ZWPA 1C23A 2B3KA 1JAWA 2V6CA 2V3YA 4FLLA 1WY2A 1C27A 2Q94A 3FMQA 4U70A 2IW2A 5CDVA 4IF7A 2GG9A 2BWVA 1QXZA 2BWSA 4U6WA 4EGEA 4U75A 2NQ6A 2Q8KA 2GZ5A 5CNXA 1M35A 1W2MA 2EA4A 2GG7A 3PKEA 2OKNA 2GA2A 1O0XA 1C22A 5FCFA 5CDLA 2V3ZA 2BB7A 4IKUA 3BIPA 1W7VA 2HOWA 4KM3A 4PNCA 4QR8A 2BHDA 2ADUA 2GG3A 3FM3A 4IECA 3FMRA 4IKTA 1XGNA 4MATA 2B3LA 4FO7A 4U6ZA 1WKMA 4HXXA 4FLKA 2BWYA 3RVAA 4FLJA 4ZWOA 1WBQA 1BN5A 4RZZA 4U1BA 1WN1A 1XGOA 2GG8A 1B59A 3BIQA 3L24A 2Q95A 1KQ9A 3L7GA 5FCHA 5JHUA 4PV4A 1QXYA 2GU4A 4OOKA 3IG4A 3TAVA 2EA2A 1KQ0A 4IKSA 5CE6A 1B6AA 1MATA 4JUQA 4ZNGA 3D27A 5JFRA 2B3HA 1YVMA 3TB5A 1XNZA 4FUKA 1YW9A 1A16A 2BHBA 4IKRA 4FKCA 2GG2A 2GU7A 2GG0A 2P98A 4U71A 3PKDA 3CB6A 2MATA 2GTXA 2GU5A 2GGCA 3S6BA 4B28A 1KP0A 1XGMA 5D6FA 3CB5A 2EVMA 2EVCA 3PKCA 5CDEA 2BWXA 1PV9A 1QXWA 4IPAA 2Q93A 2BH3A 2DFIA 3PKAA 2BHAA 4A6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QZY A;  3IU8 A;  3MX6 A;  2EVO A;  4U6C A;  4IDY A;  4FLI A;  2ZSG A;  3IU7 A;  5JI6 A;  1BOA A;  5CIK A;  2V3X A;  1CHM A;  4S01 A;  1C21 A;  4RZY A;  1YW7 A;  1R58 A;  1YW8 A;  2G6P A;  5E5B A;  1YJ3 A;  2GG5 A;  4Z7M A;  2NQ7 A;  1WL6 A;  2BWU A;  3Q6D A;  4RGZ 1;  3MR1 A;  1R5G A;  4S2R P;  1WLR A;  3CTZ A;  3ROR A;  5D6E A;  1R5H A;  4IU6 A;  1XGS A;  4U76 A;  1N51 A;  2OAZ A;  3MAT A;  2P99 A;  3IU9 A;  5CLS A;  4ZWU A;  3PKB A;  4S2T P;  1Y1N A;  4U69 A;  4U73 A;  2BWW A;  4FO8 A;  4A6V A;  2Q96 A;  2BN7 A;  3BIT A;  4S00 A;  2GGB A;  4U6J A;  4R60 A;  4U6E A;  2BHC A;  1WL9 A;  2BWT A;  2P9A A;  1C24 A;  2Q92 A;  2GU6 A;  4ZWP A;  1C23 A;  2B3K A;  1JAW A;  2V6C A;  2V3Y A;  4FLL A;  1WY2 A;  1C27 A;  2Q94 A;  3FMQ A;  4U70 A;  2IW2 A;  5CDV A;  4IF7 A;  2GG9 A;  2BWV A;  1QXZ A;  2BWS A;  4U6W A;  4EGE A;  4U75 A;  2NQ6 A;  2Q8K A;  2GZ5 A;  5CNX A;  1M35 A;  1W2M A;  2EA4 A;  2GG7 A;  3PKE A;  2OKN A;  2GA2 A;  1O0X A;  1C22 A;  5FCF A;  5CDL A;  2V3Z A;  2BB7 A;  4IKU A;  3BIP A;  1W7V A;  2HOW A;  4KM3 A;  4PNC A;  4QR8 A;  2BHD A;  2ADU A;  2GG3 A;  3FM3 A;  4IEC A;  3FMR A;  4IKT A;  1XGN A;  4MAT A;  2B3L A;  4FO7 A;  4U6Z A;  1WKM A;  4HXX A;  4FLK A;  2BWY A;  3RVA A;  4FLJ A;  4ZWO A;  1WBQ A;  1BN5 A;  4RZZ A;  4U1B A;  1WN1 A;  1XGO A;  2GG8 A;  1B59 A;  3BIQ A;  3L24 A;  2Q95 A;  1KQ9 A;  3L7G A;  5FCH A;  5JHU A;  4PV4 A;  1QXY A;  2GU4 A;  4OOK A;  3IG4 A;  3TAV A;  2EA2 A;  1KQ0 A;  4IKS A;  5CE6 A;  1B6A A;  1MAT A;  4JUQ A;  4ZNG A;  3D27 A;  5JFR A;  2B3H A;  1YVM A;  3TB5 A;  1XNZ A;  4FUK A;  1YW9 A;  1A16 A;  2BHB A;  4IKR A;  4FKC A;  2GG2 A;  2GU7 A;  2GG0 A;  2P98 A;  4U71 A;  3PKD A;  3CB6 A;  2MAT A;  2GTX A;  2GU5 A;  2GGC A;  3S6B A;  4B28 A;  1KP0 A;  1XGM A;  5D6F A;  3CB5 A;  2EVM A;  2EVC A;  3PKC A;  5CDE A;  2BWX A;  1PV9 A;  1QXW A;  4IPA A;  2Q93 A;  2BH3 A;  2DFI A;  3PKA A;  2BHA A;  4A6W A; 
#chains in the Genus database with same CATH topology
 1QZY A;  3IU8 A;  3MX6 A;  2EVO A;  4U6C A;  4IDY A;  4FLI A;  2ZSG A;  3IU7 A;  5JI6 A;  1BOA A;  5CIK A;  2V3X A;  1CHM A;  4S01 A;  1C21 A;  4RZY A;  1YW7 A;  1R58 A;  1YW8 A;  2G6P A;  5E5B A;  1YJ3 A;  2GG5 A;  4Z7M A;  2NQ7 A;  1WL6 A;  2BWU A;  3Q6D A;  4RGZ 1;  3MR1 A;  1R5G A;  4S2R P;  1WLR A;  3CTZ A;  3ROR A;  5D6E A;  1R5H A;  4IU6 A;  1XGS A;  4U76 A;  1N51 A;  2OAZ A;  3MAT A;  2P99 A;  3IU9 A;  5CLS A;  4ZWU A;  3PKB A;  4S2T P;  1Y1N A;  4U69 A;  4U73 A;  2BWW A;  4FO8 A;  4A6V A;  2Q96 A;  2BN7 A;  3BIT A;  4S00 A;  2GGB A;  4U6J A;  4R60 A;  4U6E A;  2BHC A;  1WL9 A;  2BWT A;  2P9A A;  1C24 A;  2Q92 A;  2GU6 A;  4ZWP A;  1C23 A;  2B3K A;  1JAW A;  2V6C A;  2V3Y A;  4FLL A;  1WY2 A;  1C27 A;  2Q94 A;  3FMQ A;  4U70 A;  2IW2 A;  5CDV A;  4IF7 A;  2GG9 A;  2BWV A;  1QXZ A;  2BWS A;  4U6W A;  4EGE A;  4U75 A;  2NQ6 A;  2Q8K A;  2GZ5 A;  5CNX A;  1M35 A;  1W2M A;  2EA4 A;  2GG7 A;  3PKE A;  2OKN A;  2GA2 A;  1O0X A;  1C22 A;  5FCF A;  5CDL A;  2V3Z A;  2BB7 A;  4IKU A;  3BIP A;  1W7V A;  2HOW A;  4KM3 A;  4PNC A;  4QR8 A;  2BHD A;  2ADU A;  2GG3 A;  3FM3 A;  4IEC A;  3FMR A;  4IKT A;  1XGN A;  4MAT A;  2B3L A;  4FO7 A;  4U6Z A;  1WKM A;  4HXX A;  4FLK A;  2BWY A;  3RVA A;  4FLJ A;  4ZWO A;  1WBQ A;  1BN5 A;  4RZZ A;  4U1B A;  1WN1 A;  1XGO A;  2GG8 A;  1B59 A;  3BIQ A;  3L24 A;  2Q95 A;  1KQ9 A;  3L7G A;  5FCH A;  5JHU A;  4PV4 A;  1QXY A;  2GU4 A;  4OOK A;  3IG4 A;  3TAV A;  2EA2 A;  1KQ0 A;  4IKS A;  5CE6 A;  1B6A A;  1MAT A;  4JUQ A;  4ZNG A;  3D27 A;  5JFR A;  2B3H A;  1YVM A;  3TB5 A;  1XNZ A;  4FUK A;  1YW9 A;  1A16 A;  2BHB A;  4IKR A;  4FKC A;  2GG2 A;  2GU7 A;  2GG0 A;  2P98 A;  4U71 A;  3PKD A;  3CB6 A;  2MAT A;  2GTX A;  2GU5 A;  2GGC A;  3S6B A;  4B28 A;  1KP0 A;  1XGM A;  5D6F A;  3CB5 A;  2EVM A;  2EVC A;  3PKC A;  5CDE A;  2BWX A;  1PV9 A;  1QXW A;  4IPA A;  2Q93 A;  2BH3 A;  2DFI A;  3PKA A;  2BHA A;  4A6W A; 
#chains in the Genus database with same CATH homology
 1QZY A;  3IU8 A;  3MX6 A;  2EVO A;  4U6C A;  4IDY A;  4FLI A;  2ZSG A;  3IU7 A;  5JI6 A;  1BOA A;  5CIK A;  2V3X A;  1CHM A;  4S01 A;  1C21 A;  4RZY A;  1YW7 A;  1R58 A;  1YW8 A;  2G6P A;  5E5B A;  1YJ3 A;  2GG5 A;  4Z7M A;  2NQ7 A;  1WL6 A;  2BWU A;  3Q6D A;  4RGZ 1;  3MR1 A;  1R5G A;  4S2R P;  1WLR A;  3CTZ A;  3ROR A;  5D6E A;  1R5H A;  4IU6 A;  1XGS A;  4U76 A;  1N51 A;  2OAZ A;  3MAT A;  2P99 A;  3IU9 A;  5CLS A;  4ZWU A;  3PKB A;  4S2T P;  1Y1N A;  4U69 A;  4U73 A;  2BWW A;  4FO8 A;  4A6V A;  2Q96 A;  2BN7 A;  3BIT A;  4S00 A;  2GGB A;  4U6J A;  4R60 A;  4U6E A;  2BHC A;  1WL9 A;  2BWT A;  2P9A A;  1C24 A;  2Q92 A;  2GU6 A;  4ZWP A;  1C23 A;  2B3K A;  1JAW A;  2V6C A;  2V3Y A;  4FLL A;  1WY2 A;  1C27 A;  2Q94 A;  3FMQ A;  4U70 A;  2IW2 A;  5CDV A;  4IF7 A;  2GG9 A;  2BWV A;  1QXZ A;  2BWS A;  4U6W A;  4EGE A;  4U75 A;  2NQ6 A;  2Q8K A;  2GZ5 A;  5CNX A;  1M35 A;  1W2M A;  2EA4 A;  2GG7 A;  3PKE A;  2OKN A;  2GA2 A;  1O0X A;  1C22 A;  5FCF A;  5CDL A;  2V3Z A;  2BB7 A;  4IKU A;  3BIP A;  1W7V A;  2HOW A;  4KM3 A;  4PNC A;  4QR8 A;  2BHD A;  2ADU A;  2GG3 A;  3FM3 A;  4IEC A;  3FMR A;  4IKT A;  1XGN A;  4MAT A;  2B3L A;  4FO7 A;  4U6Z A;  1WKM A;  4HXX A;  4FLK A;  2BWY A;  3RVA A;  4FLJ A;  4ZWO A;  1WBQ A;  1BN5 A;  4RZZ A;  4U1B A;  1WN1 A;  1XGO A;  2GG8 A;  1B59 A;  3BIQ A;  3L24 A;  2Q95 A;  1KQ9 A;  3L7G A;  5FCH A;  5JHU A;  4PV4 A;  1QXY A;  2GU4 A;  4OOK A;  3IG4 A;  3TAV A;  2EA2 A;  1KQ0 A;  4IKS A;  5CE6 A;  1B6A A;  1MAT A;  4JUQ A;  4ZNG A;  3D27 A;  5JFR A;  2B3H A;  1YVM A;  3TB5 A;  1XNZ A;  4FUK A;  1YW9 A;  1A16 A;  2BHB A;  4IKR A;  4FKC A;  2GG2 A;  2GU7 A;  2GG0 A;  2P98 A;  4U71 A;  3PKD A;  3CB6 A;  2MAT A;  2GTX A;  2GU5 A;  2GGC A;  3S6B A;  4B28 A;  1KP0 A;  1XGM A;  5D6F A;  3CB5 A;  2EVM A;  2EVC A;  3PKC A;  5CDE A;  2BWX A;  1PV9 A;  1QXW A;  4IPA A;  2Q93 A;  2BH3 A;  2DFI A;  3PKA A;  2BHA A;  4A6W A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...