2V3YA

His361ala escherichia coli aminopeptidase p in complex with product
Total Genus 158
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
158
sequence length
440
structure length
439
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENEEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVADVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Complexes of Mutants of Escherichia Coli Aminopeptidase P and the Tripeptide Substrate Valproleu.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords XAA-PRO AMINOPEPTIDASE
total genus 158
structure length 439
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2007-06-25

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2v3yA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2v3yA02
2DFIA 2BWXA 2BHCA 3MX6A 4IKSA 4U6EA 1WY2A 2EVOA 4MATA 2BN7A 3TB5A 2GG0A 2GU6A 2BWTA 3PKAA 4IU6A 3OOOA 1W7VA 5FCFA 2EVMA 2GG2A 3D27A 2BWSA 5E5BA 4S2RP 1XGMA 2HOWA 1O0XA 1WL6A 3BIPA 1YJ3A 2GTXA 4FLLA 3OVKA 4R60A 2P99A 4S01A 3FMQA 5FCHA 2BWUA 4A6VA 4JUQA 2Q94A 3CTZA 4IKRA 2BHDA 2EA2A 1R5GA 3L24A 3S6BA 5D6EA 2GU4A 4IDYA 4ZWUA 4U76A 2P9AA 2Q92A 1A16A 3QOCA 1WLRA 1QXZA 2Q93A 3PKDA 4S2TP 3PKEA 3CB5A 1R5HA 1WN1A 2GA2A 3PKBA 1JAWA 2GG3A 4ZWPA 4IKTA 3CB6A 4IF7A 2OAZA 4FLKA 4Z7MA 1QXYA 2GGBA 1C23A 2ZSGA 5CNXA 4RZYA 4ZWOA 2V3ZA 2B3LA 3IG4A 4U70A 1XNZA 3IU7A 5D6FA 3IL0A 5CDEA 2MATA 1N51A 3L7GA 4U75A 1XGOA 2EA4A 1QXWA 1R58A 1YVMA 4U6ZA 5CDVA 2GGCA 1WBQA 2GG8A 4IECA 1WKMA 4KM3A 1B59A 1B6AA 2V3YA 4PNCA 4FLIA 2OKNA 4FKCA 3BITA 1Y1NA 1KQ0A 3BIQA 4U69A 2GU5A 4EGEA 3I7MA 3FM3A 1YW7A 4RGZ1 1BN5A 3FMRA 5JHUA 1M35A 3O5VA 1XGNA 2B3KA 5CIKA 1XGSA 5CE6A 4OOKA 2Q96A 4PV4A 5CDLA 2GZ5A 1C21A 4ZNGA 1QZYA 3IU9A 4FUKA 1YW9A 4U71A 2V3XA 1PV9A 4HXXA 4RZZA 2GG7A 5JFRA 1MATA 1WL9A 2BB7A 2GG9A 4FO7A 2GG5A 4QR8A 2V6CA 1C24A 2BWYA 4IKUA 4S00A 1BOAA 5CLSA 3RORA 3PKCA 2ADUA 1C27A 2BHBA 5JI6A 1CHMA 2BWWA 1YW8A 3TAVA 1KP0A 2BWVA 4IPAA 1C22A 4U1BA 2EVCA 1KQ9A 4U6WA 2P98A 3RVAA 2NQ6A 2G6PA 1W2MA 2NQ7A 3PN9A 4FLJA 2Q8KA 5E2CA 2GU7A 4B28A 3IU8A 4A6WA 4FO8A 4U6CA 2BH3A 2IW2A 3MR1A 3MATA 4U73A 2BHAA 3PEBA 2B3HA 4U6JA 2Q95A 3Q6DA
chains in the Genus database with same CATH superfamily
2DFIA 2BWXA 2BHCA 3MX6A 4IKSA 4U6EA 1WY2A 2EVOA 4MATA 2BN7A 3TB5A 2GG0A 2GU6A 2BWTA 3PKAA 4IU6A 3OOOA 1W7VA 5FCFA 2EVMA 2GG2A 3D27A 2BWSA 5E5BA 4S2RP 1XGMA 2HOWA 1O0XA 1WL6A 3BIPA 1YJ3A 2GTXA 4FLLA 3OVKA 4R60A 2P99A 4S01A 3FMQA 5FCHA 2BWUA 4A6VA 4JUQA 2Q94A 3CTZA 4IKRA 2BHDA 2EA2A 1R5GA 3L24A 3S6BA 5D6EA 2GU4A 4IDYA 4ZWUA 4U76A 2P9AA 2Q92A 1A16A 3QOCA 1WLRA 1QXZA 2Q93A 3PKDA 4S2TP 3PKEA 3CB5A 1R5HA 1WN1A 2GA2A 3PKBA 1JAWA 2GG3A 4ZWPA 4IKTA 3CB6A 4IF7A 2OAZA 4FLKA 4Z7MA 1QXYA 2GGBA 1C23A 2ZSGA 5CNXA 4RZYA 4ZWOA 2V3ZA 2B3LA 3IG4A 4U70A 1XNZA 3IU7A 5D6FA 3IL0A 5CDEA 2MATA 1N51A 3L7GA 4U75A 1XGOA 2EA4A 1QXWA 1R58A 1YVMA 4U6ZA 5CDVA 2GGCA 1WBQA 2GG8A 4IECA 1WKMA 4KM3A 1B59A 1B6AA 2V3YA 4PNCA 4FLIA 2OKNA 4FKCA 3BITA 1Y1NA 1KQ0A 3BIQA 4U69A 2GU5A 4EGEA 3I7MA 3FM3A 1YW7A 4RGZ1 1BN5A 3FMRA 5JHUA 1M35A 3O5VA 1XGNA 2B3KA 5CIKA 1XGSA 5CE6A 4OOKA 2Q96A 4PV4A 5CDLA 2GZ5A 1C21A 4ZNGA 1QZYA 3IU9A 4FUKA 1YW9A 4U71A 2V3XA 1PV9A 4HXXA 4RZZA 2GG7A 5JFRA 1MATA 1WL9A 2BB7A 2GG9A 4FO7A 2GG5A 4QR8A 2V6CA 1C24A 2BWYA 4IKUA 4S00A 1BOAA 5CLSA 3RORA 3PKCA 2ADUA 1C27A 2BHBA 5JI6A 1CHMA 2BWWA 1YW8A 3TAVA 1KP0A 2BWVA 4IPAA 1C22A 4U1BA 2EVCA 1KQ9A 4U6WA 2P98A 3RVAA 2NQ6A 2G6PA 1W2MA 2NQ7A 3PN9A 4FLJA 2Q8KA 5E2CA 2GU7A 4B28A 3IU8A 4A6WA 4FO8A 4U6CA 2BH3A 2IW2A 3MR1A 3MATA 4U73A 2BHAA 3PEBA 2B3HA 4U6JA 2Q95A 3Q6DA
chains in the Genus database with same CATH topology
2DFIA 2BWXA 2BHCA 3MX6A 4IKSA 4U6EA 1WY2A 2EVOA 4MATA 2BN7A 3TB5A 2GG0A 2GU6A 2BWTA 3PKAA 4IU6A 3OOOA 1W7VA 5FCFA 2EVMA 2GG2A 3D27A 2BWSA 5E5BA 4S2RP 1XGMA 2HOWA 1O0XA 1WL6A 3BIPA 1YJ3A 2GTXA 4FLLA 3OVKA 4R60A 2P99A 4S01A 3FMQA 5FCHA 2BWUA 4A6VA 4JUQA 2Q94A 3CTZA 4IKRA 2BHDA 2EA2A 1R5GA 3L24A 3S6BA 5D6EA 2GU4A 4IDYA 4ZWUA 4U76A 2P9AA 2Q92A 1A16A 3QOCA 1WLRA 1QXZA 2Q93A 3PKDA 4S2TP 3PKEA 3CB5A 1R5HA 1WN1A 2GA2A 3PKBA 1JAWA 2GG3A 4ZWPA 4IKTA 3CB6A 4IF7A 2OAZA 4FLKA 4Z7MA 1QXYA 2GGBA 1C23A 2ZSGA 5CNXA 4RZYA 4ZWOA 2V3ZA 2B3LA 3IG4A 4U70A 1XNZA 3IU7A 5D6FA 3IL0A 5CDEA 2MATA 1N51A 3L7GA 4U75A 1XGOA 2EA4A 1QXWA 1R58A 1YVMA 4U6ZA 5CDVA 2GGCA 1WBQA 2GG8A 4IECA 1WKMA 4KM3A 1B59A 1B6AA 2V3YA 4PNCA 4FLIA 2OKNA 4FKCA 3BITA 1Y1NA 1KQ0A 3BIQA 4U69A 2GU5A 4EGEA 3I7MA 3FM3A 1YW7A 4RGZ1 1BN5A 3FMRA 5JHUA 1M35A 3O5VA 1XGNA 2B3KA 5CIKA 1XGSA 5CE6A 4OOKA 2Q96A 4PV4A 5CDLA 2GZ5A 1C21A 4ZNGA 1QZYA 3IU9A 4FUKA 1YW9A 4U71A 2V3XA 1PV9A 4HXXA 4RZZA 2GG7A 5JFRA 1MATA 1WL9A 2BB7A 2GG9A 4FO7A 2GG5A 4QR8A 2V6CA 1C24A 2BWYA 4IKUA 4S00A 1BOAA 5CLSA 3RORA 3PKCA 2ADUA 1C27A 2BHBA 5JI6A 1CHMA 2BWWA 1YW8A 3TAVA 1KP0A 2BWVA 4IPAA 1C22A 4U1BA 2EVCA 1KQ9A 4U6WA 2P98A 3RVAA 2NQ6A 2G6PA 1W2MA 2NQ7A 3PN9A 4FLJA 2Q8KA 5E2CA 2GU7A 4B28A 3IU8A 4A6WA 4FO8A 4U6CA 2BH3A 2IW2A 3MR1A 3MATA 4U73A 2BHAA 3PEBA 2B3HA 4U6JA 2Q95A 3Q6DA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2DFI A;  2BWX A;  2BHC A;  3MX6 A;  4IKS A;  4U6E A;  1WY2 A;  2EVO A;  4MAT A;  2BN7 A;  3TB5 A;  2GG0 A;  2GU6 A;  2BWT A;  3PKA A;  4IU6 A;  3OOO A;  1W7V A;  5FCF A;  2EVM A;  2GG2 A;  3D27 A;  2BWS A;  5E5B A;  4S2R P;  1XGM A;  2HOW A;  1O0X A;  1WL6 A;  3BIP A;  1YJ3 A;  2GTX A;  4FLL A;  3OVK A;  4R60 A;  2P99 A;  4S01 A;  3FMQ A;  5FCH A;  2BWU A;  4A6V A;  4JUQ A;  2Q94 A;  3CTZ A;  4IKR A;  2BHD A;  2EA2 A;  1R5G A;  3L24 A;  3S6B A;  5D6E A;  2GU4 A;  4IDY A;  4ZWU A;  4U76 A;  2P9A A;  2Q92 A;  1A16 A;  3QOC A;  1WLR A;  1QXZ A;  2Q93 A;  3PKD A;  4S2T P;  3PKE A;  3CB5 A;  1R5H A;  1WN1 A;  2GA2 A;  3PKB A;  1JAW A;  2GG3 A;  4ZWP A;  4IKT A;  3CB6 A;  4IF7 A;  2OAZ A;  4FLK A;  4Z7M A;  1QXY A;  2GGB A;  1C23 A;  2ZSG A;  5CNX A;  4RZY A;  4ZWO A;  2V3Z A;  2B3L A;  3IG4 A;  4U70 A;  1XNZ A;  3IU7 A;  5D6F A;  3IL0 A;  5CDE A;  2MAT A;  1N51 A;  3L7G A;  4U75 A;  1XGO A;  2EA4 A;  1QXW A;  1R58 A;  1YVM A;  4U6Z A;  5CDV A;  2GGC A;  1WBQ A;  2GG8 A;  4IEC A;  1WKM A;  4KM3 A;  1B59 A;  1B6A A;  2V3Y A;  4PNC A;  4FLI A;  2OKN A;  4FKC A;  3BIT A;  1Y1N A;  1KQ0 A;  3BIQ A;  4U69 A;  2GU5 A;  4EGE A;  3I7M A;  3FM3 A;  1YW7 A;  4RGZ 1;  1BN5 A;  3FMR A;  5JHU A;  1M35 A;  3O5V A;  1XGN A;  2B3K A;  5CIK A;  1XGS A;  5CE6 A;  4OOK A;  2Q96 A;  4PV4 A;  5CDL A;  2GZ5 A;  1C21 A;  4ZNG A;  1QZY A;  3IU9 A;  4FUK A;  1YW9 A;  4U71 A;  2V3X A;  1PV9 A;  4HXX A;  4RZZ A;  2GG7 A;  5JFR A;  1MAT A;  1WL9 A;  2BB7 A;  2GG9 A;  4FO7 A;  2GG5 A;  4QR8 A;  2V6C A;  1C24 A;  2BWY A;  4IKU A;  4S00 A;  1BOA A;  5CLS A;  3ROR A;  3PKC A;  2ADU A;  1C27 A;  2BHB A;  5JI6 A;  1CHM A;  2BWW A;  1YW8 A;  3TAV A;  1KP0 A;  2BWV A;  4IPA A;  1C22 A;  4U1B A;  2EVC A;  1KQ9 A;  4U6W A;  2P98 A;  3RVA A;  2NQ6 A;  2G6P A;  1W2M A;  2NQ7 A;  3PN9 A;  4FLJ A;  2Q8K A;  5E2C A;  2GU7 A;  4B28 A;  3IU8 A;  4A6W A;  4FO8 A;  4U6C A;  2BH3 A;  2IW2 A;  3MR1 A;  3MAT A;  4U73 A;  2BHA A;  3PEB A;  2B3H A;  4U6J A;  2Q95 A;  3Q6D A; 
#chains in the Genus database with same CATH topology
 2DFI A;  2BWX A;  2BHC A;  3MX6 A;  4IKS A;  4U6E A;  1WY2 A;  2EVO A;  4MAT A;  2BN7 A;  3TB5 A;  2GG0 A;  2GU6 A;  2BWT A;  3PKA A;  4IU6 A;  3OOO A;  1W7V A;  5FCF A;  2EVM A;  2GG2 A;  3D27 A;  2BWS A;  5E5B A;  4S2R P;  1XGM A;  2HOW A;  1O0X A;  1WL6 A;  3BIP A;  1YJ3 A;  2GTX A;  4FLL A;  3OVK A;  4R60 A;  2P99 A;  4S01 A;  3FMQ A;  5FCH A;  2BWU A;  4A6V A;  4JUQ A;  2Q94 A;  3CTZ A;  4IKR A;  2BHD A;  2EA2 A;  1R5G A;  3L24 A;  3S6B A;  5D6E A;  2GU4 A;  4IDY A;  4ZWU A;  4U76 A;  2P9A A;  2Q92 A;  1A16 A;  3QOC A;  1WLR A;  1QXZ A;  2Q93 A;  3PKD A;  4S2T P;  3PKE A;  3CB5 A;  1R5H A;  1WN1 A;  2GA2 A;  3PKB A;  1JAW A;  2GG3 A;  4ZWP A;  4IKT A;  3CB6 A;  4IF7 A;  2OAZ A;  4FLK A;  4Z7M A;  1QXY A;  2GGB A;  1C23 A;  2ZSG A;  5CNX A;  4RZY A;  4ZWO A;  2V3Z A;  2B3L A;  3IG4 A;  4U70 A;  1XNZ A;  3IU7 A;  5D6F A;  3IL0 A;  5CDE A;  2MAT A;  1N51 A;  3L7G A;  4U75 A;  1XGO A;  2EA4 A;  1QXW A;  1R58 A;  1YVM A;  4U6Z A;  5CDV A;  2GGC A;  1WBQ A;  2GG8 A;  4IEC A;  1WKM A;  4KM3 A;  1B59 A;  1B6A A;  2V3Y A;  4PNC A;  4FLI A;  2OKN A;  4FKC A;  3BIT A;  1Y1N A;  1KQ0 A;  3BIQ A;  4U69 A;  2GU5 A;  4EGE A;  3I7M A;  3FM3 A;  1YW7 A;  4RGZ 1;  1BN5 A;  3FMR A;  5JHU A;  1M35 A;  3O5V A;  1XGN A;  2B3K A;  5CIK A;  1XGS A;  5CE6 A;  4OOK A;  2Q96 A;  4PV4 A;  5CDL A;  2GZ5 A;  1C21 A;  4ZNG A;  1QZY A;  3IU9 A;  4FUK A;  1YW9 A;  4U71 A;  2V3X A;  1PV9 A;  4HXX A;  4RZZ A;  2GG7 A;  5JFR A;  1MAT A;  1WL9 A;  2BB7 A;  2GG9 A;  4FO7 A;  2GG5 A;  4QR8 A;  2V6C A;  1C24 A;  2BWY A;  4IKU A;  4S00 A;  1BOA A;  5CLS A;  3ROR A;  3PKC A;  2ADU A;  1C27 A;  2BHB A;  5JI6 A;  1CHM A;  2BWW A;  1YW8 A;  3TAV A;  1KP0 A;  2BWV A;  4IPA A;  1C22 A;  4U1B A;  2EVC A;  1KQ9 A;  4U6W A;  2P98 A;  3RVA A;  2NQ6 A;  2G6P A;  1W2M A;  2NQ7 A;  3PN9 A;  4FLJ A;  2Q8K A;  5E2C A;  2GU7 A;  4B28 A;  3IU8 A;  4A6W A;  4FO8 A;  4U6C A;  2BH3 A;  2IW2 A;  3MR1 A;  3MAT A;  4U73 A;  2BHA A;  3PEB A;  2B3H A;  4U6J A;  2Q95 A;  3Q6D A; 
#chains in the Genus database with same CATH homology
 2DFI A;  2BWX A;  2BHC A;  3MX6 A;  4IKS A;  4U6E A;  1WY2 A;  2EVO A;  4MAT A;  2BN7 A;  3TB5 A;  2GG0 A;  2GU6 A;  2BWT A;  3PKA A;  4IU6 A;  3OOO A;  1W7V A;  5FCF A;  2EVM A;  2GG2 A;  3D27 A;  2BWS A;  5E5B A;  4S2R P;  1XGM A;  2HOW A;  1O0X A;  1WL6 A;  3BIP A;  1YJ3 A;  2GTX A;  4FLL A;  3OVK A;  4R60 A;  2P99 A;  4S01 A;  3FMQ A;  5FCH A;  2BWU A;  4A6V A;  4JUQ A;  2Q94 A;  3CTZ A;  4IKR A;  2BHD A;  2EA2 A;  1R5G A;  3L24 A;  3S6B A;  5D6E A;  2GU4 A;  4IDY A;  4ZWU A;  4U76 A;  2P9A A;  2Q92 A;  1A16 A;  3QOC A;  1WLR A;  1QXZ A;  2Q93 A;  3PKD A;  4S2T P;  3PKE A;  3CB5 A;  1R5H A;  1WN1 A;  2GA2 A;  3PKB A;  1JAW A;  2GG3 A;  4ZWP A;  4IKT A;  3CB6 A;  4IF7 A;  2OAZ A;  4FLK A;  4Z7M A;  1QXY A;  2GGB A;  1C23 A;  2ZSG A;  5CNX A;  4RZY A;  4ZWO A;  2V3Z A;  2B3L A;  3IG4 A;  4U70 A;  1XNZ A;  3IU7 A;  5D6F A;  3IL0 A;  5CDE A;  2MAT A;  1N51 A;  3L7G A;  4U75 A;  1XGO A;  2EA4 A;  1QXW A;  1R58 A;  1YVM A;  4U6Z A;  5CDV A;  2GGC A;  1WBQ A;  2GG8 A;  4IEC A;  1WKM A;  4KM3 A;  1B59 A;  1B6A A;  2V3Y A;  4PNC A;  4FLI A;  2OKN A;  4FKC A;  3BIT A;  1Y1N A;  1KQ0 A;  3BIQ A;  4U69 A;  2GU5 A;  4EGE A;  3I7M A;  3FM3 A;  1YW7 A;  4RGZ 1;  1BN5 A;  3FMR A;  5JHU A;  1M35 A;  3O5V A;  1XGN A;  2B3K A;  5CIK A;  1XGS A;  5CE6 A;  4OOK A;  2Q96 A;  4PV4 A;  5CDL A;  2GZ5 A;  1C21 A;  4ZNG A;  1QZY A;  3IU9 A;  4FUK A;  1YW9 A;  4U71 A;  2V3X A;  1PV9 A;  4HXX A;  4RZZ A;  2GG7 A;  5JFR A;  1MAT A;  1WL9 A;  2BB7 A;  2GG9 A;  4FO7 A;  2GG5 A;  4QR8 A;  2V6C A;  1C24 A;  2BWY A;  4IKU A;  4S00 A;  1BOA A;  5CLS A;  3ROR A;  3PKC A;  2ADU A;  1C27 A;  2BHB A;  5JI6 A;  1CHM A;  2BWW A;  1YW8 A;  3TAV A;  1KP0 A;  2BWV A;  4IPA A;  1C22 A;  4U1B A;  2EVC A;  1KQ9 A;  4U6W A;  2P98 A;  3RVA A;  2NQ6 A;  2G6P A;  1W2M A;  2NQ7 A;  3PN9 A;  4FLJ A;  2Q8K A;  5E2C A;  2GU7 A;  4B28 A;  3IU8 A;  4A6W A;  4FO8 A;  4U6C A;  2BH3 A;  2IW2 A;  3MR1 A;  3MAT A;  4U73 A;  2BHA A;  3PEB A;  2B3H A;  4U6J A;  2Q95 A;  3Q6D A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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