3TAVA

Crystal structure of a methionine aminopeptidase from mycobacterium abscessus
Total Genus 82
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
82
sequence length
264
structure length
264
Chain Sequence
VGLFGRKKTVEQRTPGELDAMAAAGSIVGAALVAVRDAAKAGVSTLELDQVAESVIREAGAVPSFLGYHGFPASICSSVNDQVVHGIPSATAVLADGDLVSIDCGAILDGWHGDSAWTFAVGTVIPSDEALSEATRLSMEAGIAAMIPGNRLTDVSHAIELGTRAAEKQFDRAFGIVDGYGGHGIGRSMHLDPFLPNEGAPGKGPLLAVGSVLAIEPMLTLGTTQTRVLADDWTVVTTDGSRAAHWEHTVAVTEAGPRILTMRP
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Increasing the structural coverage of tuberculosis drug targets.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
molecule tags Hydrolase
source organism Mycobacterium abscessus
total genus 82
structure length 264
sequence length 264
chains with identical sequence B
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-04

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tavA00
4FO7A 4U70A 3RVAA 1KQ0A 1XGMA 4IPAA 1MATA 2Q95A 3MX6A 1JAWA 4ZWPA 1QXYA 2BB7A 4IKRA 1WL9A 3S6BA 1YJ3A 4PV4A 4U6CA 4IKUA 1WBQA 2EA2A 1WL6A 4U6WA 3RORA 5JHUA 2EA4A 3BIPA 2GU5A 3FMQA 1YW7A 2Q94A 1QXWA 4FUKA 3BIQA 2BWSA 2GG0A 2GZ5A 3IU8A 4U1BA 5D6EA 1C24A 2BHDA 3PKEA 4MATA 1C22A 1C21A 3L24A 4S00A 4U75A 4RZZA 1B6AA 2B3LA 3IG4A 3IU9A 4ZNGA 2BWWA 4U6EA 5CDVA 3FM3A 4FLLA 2NQ6A 4FKCA 2ADUA 2P99A 2Q96A 4FLIA 3PKAA 4FO8A 4IKSA 1QXZA 4FLKA 4HXXA 4KM3A 4R60A 4Z7MA 1R5HA 1R5GA 5CDEA 5FCFA 2BWTA 1C23A 2BWUA 1N51A 2GGBA 4IF7A 4ZWOA 1KP0A 5CIKA 2G6PA 2GG9A 1XNZA 1YW8A 3CTZA 2GG5A 2OKNA 1CHMA 2OAZA 1C27A 3D27A 4IKTA 4IU6A 4S01A 4RZYA 4U6JA 2BHAA 4S2TP 1W2MA 2Q8KA 1WLRA 4A6WA 3TAVA 4OOKA 4IECA 1WKMA 4U71A 2BH3A 2V3XA 1XGSA 1YW9A 2BHCA 2DFIA 3CB6A 4U69A 2BWVA 4ZWUA 1Y1NA 2EVCA 2GG7A 2MATA 2Q92A 4QR8A 1WN1A 3BITA 1XGOA 3PKDA 5JFRA 4U6ZA 5E5BA 2V6CA 2BHBA 4S2RP 2GU4A 3CB5A 1R58A 2V3YA 1O0XA 1W7VA 5JI6A 2GG3A 1BN5A 3L7GA 5D6FA 1XGNA 2P9AA 2B3KA 4B28A 5CE6A 2GU7A 1KQ9A 3IU7A 5FCHA 3PKCA 4U73A 3FMRA 2BWXA 5CDLA 4EGEA 2ZSGA 1BOAA 4A6VA 5CLSA 4JUQA 1B59A 1YVMA 5CNXA 1PV9A 3TB5A 4PNCA 4RGZ1 2IW2A 2Q93A 2NQ7A 1A16A 2GG2A 3PKBA 2GU6A 4U76A 2V3ZA 2HOWA 3MATA 3Q6DA 2GG8A 2BWYA 2GTXA 1M35A 4FLJA 4IDYA 1QZYA 2GA2A 2B3HA 2BN7A 1WY2A 2GGCA 2EVOA 2EVMA 3MR1A 2P98A
chains in the Genus database with same CATH superfamily
4FO7A 4U70A 3RVAA 1KQ0A 1XGMA 4IPAA 1MATA 2Q95A 3MX6A 1JAWA 4ZWPA 1QXYA 2BB7A 4IKRA 1WL9A 3S6BA 1YJ3A 4PV4A 4U6CA 4IKUA 1WBQA 2EA2A 1WL6A 4U6WA 3RORA 5JHUA 2EA4A 3BIPA 2GU5A 3FMQA 1YW7A 2Q94A 1QXWA 4FUKA 3BIQA 2BWSA 2GG0A 2GZ5A 3IU8A 4U1BA 5D6EA 1C24A 2BHDA 3PKEA 4MATA 1C22A 1C21A 3L24A 4S00A 4U75A 4RZZA 1B6AA 2B3LA 3IG4A 3IU9A 4ZNGA 2BWWA 4U6EA 5CDVA 3FM3A 4FLLA 2NQ6A 4FKCA 2ADUA 2P99A 2Q96A 4FLIA 3PKAA 4FO8A 4IKSA 1QXZA 4FLKA 4HXXA 4KM3A 4R60A 4Z7MA 1R5HA 1R5GA 5CDEA 5FCFA 2BWTA 1C23A 2BWUA 1N51A 2GGBA 4IF7A 4ZWOA 1KP0A 5CIKA 2G6PA 2GG9A 1XNZA 1YW8A 3CTZA 2GG5A 2OKNA 1CHMA 2OAZA 1C27A 3D27A 4IKTA 4IU6A 4S01A 4RZYA 4U6JA 2BHAA 4S2TP 1W2MA 2Q8KA 1WLRA 4A6WA 3TAVA 4OOKA 4IECA 1WKMA 4U71A 2BH3A 2V3XA 1XGSA 1YW9A 2BHCA 2DFIA 3CB6A 4U69A 2BWVA 4ZWUA 1Y1NA 2EVCA 2GG7A 2MATA 2Q92A 4QR8A 1WN1A 3BITA 1XGOA 3PKDA 5JFRA 4U6ZA 5E5BA 2V6CA 2BHBA 4S2RP 2GU4A 3CB5A 1R58A 2V3YA 1O0XA 1W7VA 5JI6A 2GG3A 1BN5A 3L7GA 5D6FA 1XGNA 2P9AA 2B3KA 4B28A 5CE6A 2GU7A 1KQ9A 3IU7A 5FCHA 3PKCA 4U73A 3FMRA 2BWXA 5CDLA 4EGEA 2ZSGA 1BOAA 4A6VA 5CLSA 4JUQA 1B59A 1YVMA 5CNXA 1PV9A 3TB5A 4PNCA 4RGZ1 2IW2A 2Q93A 2NQ7A 1A16A 2GG2A 3PKBA 2GU6A 4U76A 2V3ZA 2HOWA 3MATA 3Q6DA 2GG8A 2BWYA 2GTXA 1M35A 4FLJA 4IDYA 1QZYA 2GA2A 2B3HA 2BN7A 1WY2A 2GGCA 2EVOA 2EVMA 3MR1A 2P98A
chains in the Genus database with same CATH topology
4FO7A 4U70A 3RVAA 1KQ0A 1XGMA 4IPAA 1MATA 2Q95A 3MX6A 1JAWA 4ZWPA 1QXYA 2BB7A 4IKRA 1WL9A 3S6BA 1YJ3A 4PV4A 4U6CA 4IKUA 1WBQA 2EA2A 1WL6A 4U6WA 3RORA 5JHUA 2EA4A 3BIPA 2GU5A 3FMQA 1YW7A 2Q94A 1QXWA 4FUKA 3BIQA 2BWSA 2GG0A 2GZ5A 3IU8A 4U1BA 5D6EA 1C24A 2BHDA 3PKEA 4MATA 1C22A 1C21A 3L24A 4S00A 4U75A 4RZZA 1B6AA 2B3LA 3IG4A 3IU9A 4ZNGA 2BWWA 4U6EA 5CDVA 3FM3A 4FLLA 2NQ6A 4FKCA 2ADUA 2P99A 2Q96A 4FLIA 3PKAA 4FO8A 4IKSA 1QXZA 4FLKA 4HXXA 4KM3A 4R60A 4Z7MA 1R5HA 1R5GA 5CDEA 5FCFA 2BWTA 1C23A 2BWUA 1N51A 2GGBA 4IF7A 4ZWOA 1KP0A 5CIKA 2G6PA 2GG9A 1XNZA 1YW8A 3CTZA 2GG5A 2OKNA 1CHMA 2OAZA 1C27A 3D27A 4IKTA 4IU6A 4S01A 4RZYA 4U6JA 2BHAA 4S2TP 1W2MA 2Q8KA 1WLRA 4A6WA 3TAVA 4OOKA 4IECA 1WKMA 4U71A 2BH3A 2V3XA 1XGSA 1YW9A 2BHCA 2DFIA 3CB6A 4U69A 2BWVA 4ZWUA 1Y1NA 2EVCA 2GG7A 2MATA 2Q92A 4QR8A 1WN1A 3BITA 1XGOA 3PKDA 5JFRA 4U6ZA 5E5BA 2V6CA 2BHBA 4S2RP 2GU4A 3CB5A 1R58A 2V3YA 1O0XA 1W7VA 5JI6A 2GG3A 1BN5A 3L7GA 5D6FA 1XGNA 2P9AA 2B3KA 4B28A 5CE6A 2GU7A 1KQ9A 3IU7A 5FCHA 3PKCA 4U73A 3FMRA 2BWXA 5CDLA 4EGEA 2ZSGA 1BOAA 4A6VA 5CLSA 4JUQA 1B59A 1YVMA 5CNXA 1PV9A 3TB5A 4PNCA 4RGZ1 2IW2A 2Q93A 2NQ7A 1A16A 2GG2A 3PKBA 2GU6A 4U76A 2V3ZA 2HOWA 3MATA 3Q6DA 2GG8A 2BWYA 2GTXA 1M35A 4FLJA 4IDYA 1QZYA 2GA2A 2B3HA 2BN7A 1WY2A 2GGCA 2EVOA 2EVMA 3MR1A 2P98A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4FO7 A;  4U70 A;  3RVA A;  1KQ0 A;  1XGM A;  4IPA A;  1MAT A;  2Q95 A;  3MX6 A;  1JAW A;  4ZWP A;  1QXY A;  2BB7 A;  4IKR A;  1WL9 A;  3S6B A;  1YJ3 A;  4PV4 A;  4U6C A;  4IKU A;  1WBQ A;  2EA2 A;  1WL6 A;  4U6W A;  3ROR A;  5JHU A;  2EA4 A;  3BIP A;  2GU5 A;  3FMQ A;  1YW7 A;  2Q94 A;  1QXW A;  4FUK A;  3BIQ A;  2BWS A;  2GG0 A;  2GZ5 A;  3IU8 A;  4U1B A;  5D6E A;  1C24 A;  2BHD A;  3PKE A;  4MAT A;  1C22 A;  1C21 A;  3L24 A;  4S00 A;  4U75 A;  4RZZ A;  1B6A A;  2B3L A;  3IG4 A;  3IU9 A;  4ZNG A;  2BWW A;  4U6E A;  5CDV A;  3FM3 A;  4FLL A;  2NQ6 A;  4FKC A;  2ADU A;  2P99 A;  2Q96 A;  4FLI A;  3PKA A;  4FO8 A;  4IKS A;  1QXZ A;  4FLK A;  4HXX A;  4KM3 A;  4R60 A;  4Z7M A;  1R5H A;  1R5G A;  5CDE A;  5FCF A;  2BWT A;  1C23 A;  2BWU A;  1N51 A;  2GGB A;  4IF7 A;  4ZWO A;  1KP0 A;  5CIK A;  2G6P A;  2GG9 A;  1XNZ A;  1YW8 A;  3CTZ A;  2GG5 A;  2OKN A;  1CHM A;  2OAZ A;  1C27 A;  3D27 A;  4IKT A;  4IU6 A;  4S01 A;  4RZY A;  4U6J A;  2BHA A;  4S2T P;  1W2M A;  2Q8K A;  1WLR A;  4A6W A;  3TAV A;  4OOK A;  4IEC A;  1WKM A;  4U71 A;  2BH3 A;  2V3X A;  1XGS A;  1YW9 A;  2BHC A;  2DFI A;  3CB6 A;  4U69 A;  2BWV A;  4ZWU A;  1Y1N A;  2EVC A;  2GG7 A;  2MAT A;  2Q92 A;  4QR8 A;  1WN1 A;  3BIT A;  1XGO A;  3PKD A;  5JFR A;  4U6Z A;  5E5B A;  2V6C A;  2BHB A;  4S2R P;  2GU4 A;  3CB5 A;  1R58 A;  2V3Y A;  1O0X A;  1W7V A;  5JI6 A;  2GG3 A;  1BN5 A;  3L7G A;  5D6F A;  1XGN A;  2P9A A;  2B3K A;  4B28 A;  5CE6 A;  2GU7 A;  1KQ9 A;  3IU7 A;  5FCH A;  3PKC A;  4U73 A;  3FMR A;  2BWX A;  5CDL A;  4EGE A;  2ZSG A;  1BOA A;  4A6V A;  5CLS A;  4JUQ A;  1B59 A;  1YVM A;  5CNX A;  1PV9 A;  3TB5 A;  4PNC A;  4RGZ 1;  2IW2 A;  2Q93 A;  2NQ7 A;  1A16 A;  2GG2 A;  3PKB A;  2GU6 A;  4U76 A;  2V3Z A;  2HOW A;  3MAT A;  3Q6D A;  2GG8 A;  2BWY A;  2GTX A;  1M35 A;  4FLJ A;  4IDY A;  1QZY A;  2GA2 A;  2B3H A;  2BN7 A;  1WY2 A;  2GGC A;  2EVO A;  2EVM A;  3MR1 A;  2P98 A; 
#chains in the Genus database with same CATH topology
 4FO7 A;  4U70 A;  3RVA A;  1KQ0 A;  1XGM A;  4IPA A;  1MAT A;  2Q95 A;  3MX6 A;  1JAW A;  4ZWP A;  1QXY A;  2BB7 A;  4IKR A;  1WL9 A;  3S6B A;  1YJ3 A;  4PV4 A;  4U6C A;  4IKU A;  1WBQ A;  2EA2 A;  1WL6 A;  4U6W A;  3ROR A;  5JHU A;  2EA4 A;  3BIP A;  2GU5 A;  3FMQ A;  1YW7 A;  2Q94 A;  1QXW A;  4FUK A;  3BIQ A;  2BWS A;  2GG0 A;  2GZ5 A;  3IU8 A;  4U1B A;  5D6E A;  1C24 A;  2BHD A;  3PKE A;  4MAT A;  1C22 A;  1C21 A;  3L24 A;  4S00 A;  4U75 A;  4RZZ A;  1B6A A;  2B3L A;  3IG4 A;  3IU9 A;  4ZNG A;  2BWW A;  4U6E A;  5CDV A;  3FM3 A;  4FLL A;  2NQ6 A;  4FKC A;  2ADU A;  2P99 A;  2Q96 A;  4FLI A;  3PKA A;  4FO8 A;  4IKS A;  1QXZ A;  4FLK A;  4HXX A;  4KM3 A;  4R60 A;  4Z7M A;  1R5H A;  1R5G A;  5CDE A;  5FCF A;  2BWT A;  1C23 A;  2BWU A;  1N51 A;  2GGB A;  4IF7 A;  4ZWO A;  1KP0 A;  5CIK A;  2G6P A;  2GG9 A;  1XNZ A;  1YW8 A;  3CTZ A;  2GG5 A;  2OKN A;  1CHM A;  2OAZ A;  1C27 A;  3D27 A;  4IKT A;  4IU6 A;  4S01 A;  4RZY A;  4U6J A;  2BHA A;  4S2T P;  1W2M A;  2Q8K A;  1WLR A;  4A6W A;  3TAV A;  4OOK A;  4IEC A;  1WKM A;  4U71 A;  2BH3 A;  2V3X A;  1XGS A;  1YW9 A;  2BHC A;  2DFI A;  3CB6 A;  4U69 A;  2BWV A;  4ZWU A;  1Y1N A;  2EVC A;  2GG7 A;  2MAT A;  2Q92 A;  4QR8 A;  1WN1 A;  3BIT A;  1XGO A;  3PKD A;  5JFR A;  4U6Z A;  5E5B A;  2V6C A;  2BHB A;  4S2R P;  2GU4 A;  3CB5 A;  1R58 A;  2V3Y A;  1O0X A;  1W7V A;  5JI6 A;  2GG3 A;  1BN5 A;  3L7G A;  5D6F A;  1XGN A;  2P9A A;  2B3K A;  4B28 A;  5CE6 A;  2GU7 A;  1KQ9 A;  3IU7 A;  5FCH A;  3PKC A;  4U73 A;  3FMR A;  2BWX A;  5CDL A;  4EGE A;  2ZSG A;  1BOA A;  4A6V A;  5CLS A;  4JUQ A;  1B59 A;  1YVM A;  5CNX A;  1PV9 A;  3TB5 A;  4PNC A;  4RGZ 1;  2IW2 A;  2Q93 A;  2NQ7 A;  1A16 A;  2GG2 A;  3PKB A;  2GU6 A;  4U76 A;  2V3Z A;  2HOW A;  3MAT A;  3Q6D A;  2GG8 A;  2BWY A;  2GTX A;  1M35 A;  4FLJ A;  4IDY A;  1QZY A;  2GA2 A;  2B3H A;  2BN7 A;  1WY2 A;  2GGC A;  2EVO A;  2EVM A;  3MR1 A;  2P98 A; 
#chains in the Genus database with same CATH homology
 4FO7 A;  4U70 A;  3RVA A;  1KQ0 A;  1XGM A;  4IPA A;  1MAT A;  2Q95 A;  3MX6 A;  1JAW A;  4ZWP A;  1QXY A;  2BB7 A;  4IKR A;  1WL9 A;  3S6B A;  1YJ3 A;  4PV4 A;  4U6C A;  4IKU A;  1WBQ A;  2EA2 A;  1WL6 A;  4U6W A;  3ROR A;  5JHU A;  2EA4 A;  3BIP A;  2GU5 A;  3FMQ A;  1YW7 A;  2Q94 A;  1QXW A;  4FUK A;  3BIQ A;  2BWS A;  2GG0 A;  2GZ5 A;  3IU8 A;  4U1B A;  5D6E A;  1C24 A;  2BHD A;  3PKE A;  4MAT A;  1C22 A;  1C21 A;  3L24 A;  4S00 A;  4U75 A;  4RZZ A;  1B6A A;  2B3L A;  3IG4 A;  3IU9 A;  4ZNG A;  2BWW A;  4U6E A;  5CDV A;  3FM3 A;  4FLL A;  2NQ6 A;  4FKC A;  2ADU A;  2P99 A;  2Q96 A;  4FLI A;  3PKA A;  4FO8 A;  4IKS A;  1QXZ A;  4FLK A;  4HXX A;  4KM3 A;  4R60 A;  4Z7M A;  1R5H A;  1R5G A;  5CDE A;  5FCF A;  2BWT A;  1C23 A;  2BWU A;  1N51 A;  2GGB A;  4IF7 A;  4ZWO A;  1KP0 A;  5CIK A;  2G6P A;  2GG9 A;  1XNZ A;  1YW8 A;  3CTZ A;  2GG5 A;  2OKN A;  1CHM A;  2OAZ A;  1C27 A;  3D27 A;  4IKT A;  4IU6 A;  4S01 A;  4RZY A;  4U6J A;  2BHA A;  4S2T P;  1W2M A;  2Q8K A;  1WLR A;  4A6W A;  3TAV A;  4OOK A;  4IEC A;  1WKM A;  4U71 A;  2BH3 A;  2V3X A;  1XGS A;  1YW9 A;  2BHC A;  2DFI A;  3CB6 A;  4U69 A;  2BWV A;  4ZWU A;  1Y1N A;  2EVC A;  2GG7 A;  2MAT A;  2Q92 A;  4QR8 A;  1WN1 A;  3BIT A;  1XGO A;  3PKD A;  5JFR A;  4U6Z A;  5E5B A;  2V6C A;  2BHB A;  4S2R P;  2GU4 A;  3CB5 A;  1R58 A;  2V3Y A;  1O0X A;  1W7V A;  5JI6 A;  2GG3 A;  1BN5 A;  3L7G A;  5D6F A;  1XGN A;  2P9A A;  2B3K A;  4B28 A;  5CE6 A;  2GU7 A;  1KQ9 A;  3IU7 A;  5FCH A;  3PKC A;  4U73 A;  3FMR A;  2BWX A;  5CDL A;  4EGE A;  2ZSG A;  1BOA A;  4A6V A;  5CLS A;  4JUQ A;  1B59 A;  1YVM A;  5CNX A;  1PV9 A;  3TB5 A;  4PNC A;  4RGZ 1;  2IW2 A;  2Q93 A;  2NQ7 A;  1A16 A;  2GG2 A;  3PKB A;  2GU6 A;  4U76 A;  2V3Z A;  2HOW A;  3MAT A;  3Q6D A;  2GG8 A;  2BWY A;  2GTX A;  1M35 A;  4FLJ A;  4IDY A;  1QZY A;  2GA2 A;  2B3H A;  2BN7 A;  1WY2 A;  2GGC A;  2EVO A;  2EVM A;  3MR1 A;  2P98 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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