3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
source organism Mycobacterium tuberculosis
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
3CTZA 2MATA 1YJ3A 1PV9A 1XNZA 2NQ7A 4U70A 1WN1A 4ZWPA 1WL9A 1JAWA 2NQ6A 3PKEA 3CB6A 1Y1NA 3RORA 1MATA 1R5GA 4IKUA 4FO8A 1C23A 4IECA 3MR1A 4FUKA 4U75A 2BH3A 4IPAA 1WKMA 2DFIA 5D6EA 2GG0A 5FCFA 4KM3A 3IG4A 3PKCA 2P98A 2BHDA 2GZ5A 5CIKA 4S01A 4B28A 4IKSA 3PKAA 4JUQA 5JFRA 4U6JA 1XGOA 4FKCA 2EA2A 4U73A 2Q96A 1KQ9A 3BIPA 1QZYA 1YVMA 1BN5A 3IU7A 4OOKA 4RGZ1 2OKNA 2P99A 3FMRA 2GG3A 3FMQA 1M35A 2BHCA 2B3KA 3BIQA 2GGCA 2OAZA 4PV4A 5CDEA 1XGSA 2IW2A 4U6WA 2EVMA 2BB7A 3MX6A 5E5BA 2BN7A 4HXXA 1B6AA 2BWTA 2GG8A 5D6FA 5CDLA 3FM3A 2HOWA 5JI6A 3TB5A 3CB5A 1WL6A 1R58A 4U1BA 2BWVA 4A6VA 2BHAA 4FO7A 2EA4A 1WY2A 2Q94A 2GGBA 1QXZA 2V3ZA 2EVOA 4U6ZA 1C27A 2G6PA 3MATA 4U71A 4FLIA 1C24A 4FLKA 2GG9A 2P9AA 4PNCA 1A16A 2BHBA 3S6BA 4S2RP 3IU9A 1C21A 1O0XA 4ZWOA 5CE6A 1BOAA 2BWYA 1XGMA 2GU6A 3D27A 4ZNGA 1YW8A 2ADUA 2B3LA 4IKRA 1W2MA 5FCHA 1KP0A 5CLSA 2GU5A 1QXWA 2GA2A 1N51A 3RVAA 2GG7A 2BWSA 4U6EA 1R5HA 1WLRA 2EVCA 4S00A 1W7VA 2Q95A 4FLLA 2BWWA 4Z7MA 2V3XA 3L24A 3PKBA 2Q92A 2BWXA 4R60A 4IF7A 5JHUA 2GU7A 5CNXA 4ZWUA 3BITA 2ZSGA 3TAVA 3PKDA 4U69A 2GU4A 4A6WA 1XGNA 4MATA 3L7GA 2Q8KA 1CHMA 1QXYA 4U6CA 1YW7A 3IU8A 4U76A 1KQ0A 2GG2A 4QR8A 2GTXA 2GG5A 4RZZA 4RZYA 4FLJA 5CDVA 4S2TP 4IDYA 2BWUA 4IKTA 1WBQA 1YW9A 1C22A 2V3YA 2B3HA 2Q93A 4EGEA 3Q6DA 2V6CA 1B59A 4IU6A
chains in the Genus database with same CATH superfamily
3CTZA 2MATA 1YJ3A 1PV9A 1XNZA 2NQ7A 4U70A 1WN1A 4ZWPA 1WL9A 1JAWA 2NQ6A 3PKEA 3CB6A 1Y1NA 3RORA 1MATA 1R5GA 4IKUA 4FO8A 1C23A 4IECA 3MR1A 4FUKA 4U75A 2BH3A 4IPAA 1WKMA 2DFIA 5D6EA 2GG0A 5FCFA 4KM3A 3IG4A 3PKCA 2P98A 2BHDA 2GZ5A 5CIKA 4S01A 4B28A 4IKSA 3PKAA 4JUQA 5JFRA 4U6JA 1XGOA 4FKCA 2EA2A 4U73A 2Q96A 1KQ9A 3BIPA 1QZYA 1YVMA 1BN5A 3IU7A 4OOKA 4RGZ1 2OKNA 2P99A 3FMRA 2GG3A 3FMQA 1M35A 2BHCA 2B3KA 3BIQA 2GGCA 2OAZA 4PV4A 5CDEA 1XGSA 2IW2A 4U6WA 2EVMA 2BB7A 3MX6A 5E5BA 2BN7A 4HXXA 1B6AA 2BWTA 2GG8A 5D6FA 5CDLA 3FM3A 2HOWA 5JI6A 3TB5A 3CB5A 1WL6A 1R58A 4U1BA 2BWVA 4A6VA 2BHAA 4FO7A 2EA4A 1WY2A 2Q94A 2GGBA 1QXZA 2V3ZA 2EVOA 4U6ZA 1C27A 2G6PA 3MATA 4U71A 4FLIA 1C24A 4FLKA 2GG9A 2P9AA 4PNCA 1A16A 2BHBA 3S6BA 4S2RP 3IU9A 1C21A 1O0XA 4ZWOA 5CE6A 1BOAA 2BWYA 1XGMA 2GU6A 3D27A 4ZNGA 1YW8A 2ADUA 2B3LA 4IKRA 1W2MA 5FCHA 1KP0A 5CLSA 2GU5A 1QXWA 2GA2A 1N51A 3RVAA 2GG7A 2BWSA 4U6EA 1R5HA 1WLRA 2EVCA 4S00A 1W7VA 2Q95A 4FLLA 2BWWA 4Z7MA 2V3XA 3L24A 3PKBA 2Q92A 2BWXA 4R60A 4IF7A 5JHUA 2GU7A 5CNXA 4ZWUA 3BITA 2ZSGA 3TAVA 3PKDA 4U69A 2GU4A 4A6WA 1XGNA 4MATA 3L7GA 2Q8KA 1CHMA 1QXYA 4U6CA 1YW7A 3IU8A 4U76A 1KQ0A 2GG2A 4QR8A 2GTXA 2GG5A 4RZZA 4RZYA 4FLJA 5CDVA 4S2TP 4IDYA 2BWUA 4IKTA 1WBQA 1YW9A 1C22A 2V3YA 2B3HA 2Q93A 4EGEA 3Q6DA 2V6CA 1B59A 4IU6A
chains in the Genus database with same CATH topology
3CTZA 2MATA 1YJ3A 1PV9A 1XNZA 2NQ7A 4U70A 1WN1A 4ZWPA 1WL9A 1JAWA 2NQ6A 3PKEA 3CB6A 1Y1NA 3RORA 1MATA 1R5GA 4IKUA 4FO8A 1C23A 4IECA 3MR1A 4FUKA 4U75A 2BH3A 4IPAA 1WKMA 2DFIA 5D6EA 2GG0A 5FCFA 4KM3A 3IG4A 3PKCA 2P98A 2BHDA 2GZ5A 5CIKA 4S01A 4B28A 4IKSA 3PKAA 4JUQA 5JFRA 4U6JA 1XGOA 4FKCA 2EA2A 4U73A 2Q96A 1KQ9A 3BIPA 1QZYA 1YVMA 1BN5A 3IU7A 4OOKA 4RGZ1 2OKNA 2P99A 3FMRA 2GG3A 3FMQA 1M35A 2BHCA 2B3KA 3BIQA 2GGCA 2OAZA 4PV4A 5CDEA 1XGSA 2IW2A 4U6WA 2EVMA 2BB7A 3MX6A 5E5BA 2BN7A 4HXXA 1B6AA 2BWTA 2GG8A 5D6FA 5CDLA 3FM3A 2HOWA 5JI6A 3TB5A 3CB5A 1WL6A 1R58A 4U1BA 2BWVA 4A6VA 2BHAA 4FO7A 2EA4A 1WY2A 2Q94A 2GGBA 1QXZA 2V3ZA 2EVOA 4U6ZA 1C27A 2G6PA 3MATA 4U71A 4FLIA 1C24A 4FLKA 2GG9A 2P9AA 4PNCA 1A16A 2BHBA 3S6BA 4S2RP 3IU9A 1C21A 1O0XA 4ZWOA 5CE6A 1BOAA 2BWYA 1XGMA 2GU6A 3D27A 4ZNGA 1YW8A 2ADUA 2B3LA 4IKRA 1W2MA 5FCHA 1KP0A 5CLSA 2GU5A 1QXWA 2GA2A 1N51A 3RVAA 2GG7A 2BWSA 4U6EA 1R5HA 1WLRA 2EVCA 4S00A 1W7VA 2Q95A 4FLLA 2BWWA 4Z7MA 2V3XA 3L24A 3PKBA 2Q92A 2BWXA 4R60A 4IF7A 5JHUA 2GU7A 5CNXA 4ZWUA 3BITA 2ZSGA 3TAVA 3PKDA 4U69A 2GU4A 4A6WA 1XGNA 4MATA 3L7GA 2Q8KA 1CHMA 1QXYA 4U6CA 1YW7A 3IU8A 4U76A 1KQ0A 2GG2A 4QR8A 2GTXA 2GG5A 4RZZA 4RZYA 4FLJA 5CDVA 4S2TP 4IDYA 2BWUA 4IKTA 1WBQA 1YW9A 1C22A 2V3YA 2B3HA 2Q93A 4EGEA 3Q6DA 2V6CA 1B59A 4IU6A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3CTZ A;  2MAT A;  1YJ3 A;  1PV9 A;  1XNZ A;  2NQ7 A;  4U70 A;  1WN1 A;  4ZWP A;  1WL9 A;  1JAW A;  2NQ6 A;  3PKE A;  3CB6 A;  1Y1N A;  3ROR A;  1MAT A;  1R5G A;  4IKU A;  4FO8 A;  1C23 A;  4IEC A;  3MR1 A;  4FUK A;  4U75 A;  2BH3 A;  4IPA A;  1WKM A;  2DFI A;  5D6E A;  2GG0 A;  5FCF A;  4KM3 A;  3IG4 A;  3PKC A;  2P98 A;  2BHD A;  2GZ5 A;  5CIK A;  4S01 A;  4B28 A;  4IKS A;  3PKA A;  4JUQ A;  5JFR A;  4U6J A;  1XGO A;  4FKC A;  2EA2 A;  4U73 A;  2Q96 A;  1KQ9 A;  3BIP A;  1QZY A;  1YVM A;  1BN5 A;  3IU7 A;  4OOK A;  4RGZ 1;  2OKN A;  2P99 A;  3FMR A;  2GG3 A;  3FMQ A;  1M35 A;  2BHC A;  2B3K A;  3BIQ A;  2GGC A;  2OAZ A;  4PV4 A;  5CDE A;  1XGS A;  2IW2 A;  4U6W A;  2EVM A;  2BB7 A;  3MX6 A;  5E5B A;  2BN7 A;  4HXX A;  1B6A A;  2BWT A;  2GG8 A;  5D6F A;  5CDL A;  3FM3 A;  2HOW A;  5JI6 A;  3TB5 A;  3CB5 A;  1WL6 A;  1R58 A;  4U1B A;  2BWV A;  4A6V A;  2BHA A;  4FO7 A;  2EA4 A;  1WY2 A;  2Q94 A;  2GGB A;  1QXZ A;  2V3Z A;  2EVO A;  4U6Z A;  1C27 A;  2G6P A;  3MAT A;  4U71 A;  4FLI A;  1C24 A;  4FLK A;  2GG9 A;  2P9A A;  4PNC A;  1A16 A;  2BHB A;  3S6B A;  4S2R P;  3IU9 A;  1C21 A;  1O0X A;  4ZWO A;  5CE6 A;  1BOA A;  2BWY A;  1XGM A;  2GU6 A;  3D27 A;  4ZNG A;  1YW8 A;  2ADU A;  2B3L A;  4IKR A;  1W2M A;  5FCH A;  1KP0 A;  5CLS A;  2GU5 A;  1QXW A;  2GA2 A;  1N51 A;  3RVA A;  2GG7 A;  2BWS A;  4U6E A;  1R5H A;  1WLR A;  2EVC A;  4S00 A;  1W7V A;  2Q95 A;  4FLL A;  2BWW A;  4Z7M A;  2V3X A;  3L24 A;  3PKB A;  2Q92 A;  2BWX A;  4R60 A;  4IF7 A;  5JHU A;  2GU7 A;  5CNX A;  4ZWU A;  3BIT A;  2ZSG A;  3TAV A;  3PKD A;  4U69 A;  2GU4 A;  4A6W A;  1XGN A;  4MAT A;  3L7G A;  2Q8K A;  1CHM A;  1QXY A;  4U6C A;  1YW7 A;  3IU8 A;  4U76 A;  1KQ0 A;  2GG2 A;  4QR8 A;  2GTX A;  2GG5 A;  4RZZ A;  4RZY A;  4FLJ A;  5CDV A;  4S2T P;  4IDY A;  2BWU A;  4IKT A;  1WBQ A;  1YW9 A;  1C22 A;  2V3Y A;  2B3H A;  2Q93 A;  4EGE A;  3Q6D A;  2V6C A;  1B59 A;  4IU6 A; 
#chains in the Genus database with same CATH topology
 3CTZ A;  2MAT A;  1YJ3 A;  1PV9 A;  1XNZ A;  2NQ7 A;  4U70 A;  1WN1 A;  4ZWP A;  1WL9 A;  1JAW A;  2NQ6 A;  3PKE A;  3CB6 A;  1Y1N A;  3ROR A;  1MAT A;  1R5G A;  4IKU A;  4FO8 A;  1C23 A;  4IEC A;  3MR1 A;  4FUK A;  4U75 A;  2BH3 A;  4IPA A;  1WKM A;  2DFI A;  5D6E A;  2GG0 A;  5FCF A;  4KM3 A;  3IG4 A;  3PKC A;  2P98 A;  2BHD A;  2GZ5 A;  5CIK A;  4S01 A;  4B28 A;  4IKS A;  3PKA A;  4JUQ A;  5JFR A;  4U6J A;  1XGO A;  4FKC A;  2EA2 A;  4U73 A;  2Q96 A;  1KQ9 A;  3BIP A;  1QZY A;  1YVM A;  1BN5 A;  3IU7 A;  4OOK A;  4RGZ 1;  2OKN A;  2P99 A;  3FMR A;  2GG3 A;  3FMQ A;  1M35 A;  2BHC A;  2B3K A;  3BIQ A;  2GGC A;  2OAZ A;  4PV4 A;  5CDE A;  1XGS A;  2IW2 A;  4U6W A;  2EVM A;  2BB7 A;  3MX6 A;  5E5B A;  2BN7 A;  4HXX A;  1B6A A;  2BWT A;  2GG8 A;  5D6F A;  5CDL A;  3FM3 A;  2HOW A;  5JI6 A;  3TB5 A;  3CB5 A;  1WL6 A;  1R58 A;  4U1B A;  2BWV A;  4A6V A;  2BHA A;  4FO7 A;  2EA4 A;  1WY2 A;  2Q94 A;  2GGB A;  1QXZ A;  2V3Z A;  2EVO A;  4U6Z A;  1C27 A;  2G6P A;  3MAT A;  4U71 A;  4FLI A;  1C24 A;  4FLK A;  2GG9 A;  2P9A A;  4PNC A;  1A16 A;  2BHB A;  3S6B A;  4S2R P;  3IU9 A;  1C21 A;  1O0X A;  4ZWO A;  5CE6 A;  1BOA A;  2BWY A;  1XGM A;  2GU6 A;  3D27 A;  4ZNG A;  1YW8 A;  2ADU A;  2B3L A;  4IKR A;  1W2M A;  5FCH A;  1KP0 A;  5CLS A;  2GU5 A;  1QXW A;  2GA2 A;  1N51 A;  3RVA A;  2GG7 A;  2BWS A;  4U6E A;  1R5H A;  1WLR A;  2EVC A;  4S00 A;  1W7V A;  2Q95 A;  4FLL A;  2BWW A;  4Z7M A;  2V3X A;  3L24 A;  3PKB A;  2Q92 A;  2BWX A;  4R60 A;  4IF7 A;  5JHU A;  2GU7 A;  5CNX A;  4ZWU A;  3BIT A;  2ZSG A;  3TAV A;  3PKD A;  4U69 A;  2GU4 A;  4A6W A;  1XGN A;  4MAT A;  3L7G A;  2Q8K A;  1CHM A;  1QXY A;  4U6C A;  1YW7 A;  3IU8 A;  4U76 A;  1KQ0 A;  2GG2 A;  4QR8 A;  2GTX A;  2GG5 A;  4RZZ A;  4RZY A;  4FLJ A;  5CDV A;  4S2T P;  4IDY A;  2BWU A;  4IKT A;  1WBQ A;  1YW9 A;  1C22 A;  2V3Y A;  2B3H A;  2Q93 A;  4EGE A;  3Q6D A;  2V6C A;  1B59 A;  4IU6 A; 
#chains in the Genus database with same CATH homology
 3CTZ A;  2MAT A;  1YJ3 A;  1PV9 A;  1XNZ A;  2NQ7 A;  4U70 A;  1WN1 A;  4ZWP A;  1WL9 A;  1JAW A;  2NQ6 A;  3PKE A;  3CB6 A;  1Y1N A;  3ROR A;  1MAT A;  1R5G A;  4IKU A;  4FO8 A;  1C23 A;  4IEC A;  3MR1 A;  4FUK A;  4U75 A;  2BH3 A;  4IPA A;  1WKM A;  2DFI A;  5D6E A;  2GG0 A;  5FCF A;  4KM3 A;  3IG4 A;  3PKC A;  2P98 A;  2BHD A;  2GZ5 A;  5CIK A;  4S01 A;  4B28 A;  4IKS A;  3PKA A;  4JUQ A;  5JFR A;  4U6J A;  1XGO A;  4FKC A;  2EA2 A;  4U73 A;  2Q96 A;  1KQ9 A;  3BIP A;  1QZY A;  1YVM A;  1BN5 A;  3IU7 A;  4OOK A;  4RGZ 1;  2OKN A;  2P99 A;  3FMR A;  2GG3 A;  3FMQ A;  1M35 A;  2BHC A;  2B3K A;  3BIQ A;  2GGC A;  2OAZ A;  4PV4 A;  5CDE A;  1XGS A;  2IW2 A;  4U6W A;  2EVM A;  2BB7 A;  3MX6 A;  5E5B A;  2BN7 A;  4HXX A;  1B6A A;  2BWT A;  2GG8 A;  5D6F A;  5CDL A;  3FM3 A;  2HOW A;  5JI6 A;  3TB5 A;  3CB5 A;  1WL6 A;  1R58 A;  4U1B A;  2BWV A;  4A6V A;  2BHA A;  4FO7 A;  2EA4 A;  1WY2 A;  2Q94 A;  2GGB A;  1QXZ A;  2V3Z A;  2EVO A;  4U6Z A;  1C27 A;  2G6P A;  3MAT A;  4U71 A;  4FLI A;  1C24 A;  4FLK A;  2GG9 A;  2P9A A;  4PNC A;  1A16 A;  2BHB A;  3S6B A;  4S2R P;  3IU9 A;  1C21 A;  1O0X A;  4ZWO A;  5CE6 A;  1BOA A;  2BWY A;  1XGM A;  2GU6 A;  3D27 A;  4ZNG A;  1YW8 A;  2ADU A;  2B3L A;  4IKR A;  1W2M A;  5FCH A;  1KP0 A;  5CLS A;  2GU5 A;  1QXW A;  2GA2 A;  1N51 A;  3RVA A;  2GG7 A;  2BWS A;  4U6E A;  1R5H A;  1WLR A;  2EVC A;  4S00 A;  1W7V A;  2Q95 A;  4FLL A;  2BWW A;  4Z7M A;  2V3X A;  3L24 A;  3PKB A;  2Q92 A;  2BWX A;  4R60 A;  4IF7 A;  5JHU A;  2GU7 A;  5CNX A;  4ZWU A;  3BIT A;  2ZSG A;  3TAV A;  3PKD A;  4U69 A;  2GU4 A;  4A6W A;  1XGN A;  4MAT A;  3L7G A;  2Q8K A;  1CHM A;  1QXY A;  4U6C A;  1YW7 A;  3IU8 A;  4U76 A;  1KQ0 A;  2GG2 A;  4QR8 A;  2GTX A;  2GG5 A;  4RZZ A;  4RZY A;  4FLJ A;  5CDV A;  4S2T P;  4IDY A;  2BWU A;  4IKT A;  1WBQ A;  1YW9 A;  1C22 A;  2V3Y A;  2B3H A;  2Q93 A;  4EGE A;  3Q6D A;  2V6C A;  1B59 A;  4IU6 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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