3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
4KM3A 2Q93A 4FLJA 4ZWPA 3TAVA 1WBQA 4ZWOA 4A6VA 1CHMA 2Q96A 4S2TP 4EGEA 2GU4A 1A16A 1WN1A 1XGMA 1KQ0A 3BITA 2BWVA 5D6EA 4IKUA 1W7VA 1JAWA 3BIPA 3L24A 2BHAA 4IECA 1KP0A 1R58A 4FLIA 1M35A 4U73A 1QXWA 1XGOA 2P99A 3IU8A 4ZWUA 2GG0A 2NQ6A 2GG9A 2P98A 4OOKA 2EA4A 2GU6A 2HOWA 1BOAA 1XGNA 3IU7A 4IKTA 2GG3A 5FCFA 3S6BA 2BWXA 2V6CA 5CNXA 5CDLA 1QXYA 1QZYA 1O0XA 1WL9A 3D27A 4RZZA 4RZYA 1MATA 2GG7A 1YW7A 2GU7A 4QR8A 5CLSA 2GGBA 1C22A 4IKSA 1KQ9A 2ADUA 4IDYA 4U6EA 4Z7MA 2G6PA 2GZ5A 5FCHA 2Q8KA 3PKDA 3RORA 2B3HA 1WLRA 4U70A 4U71A 3BIQA 4A6WA 2GG5A 3PKCA 4FKCA 3PKBA 1W2MA 1C24A 1YVMA 4IKRA 1N51A 2BWTA 1C23A 4FO7A 2EVMA 2OAZA 4MATA 2V3ZA 2BWUA 3PKEA 2Q95A 2OKNA 3Q6DA 4PV4A 2GG8A 4S2RP 4R60A 5JHUA 4U6ZA 4ZNGA 3CTZA 1QXZA 4HXXA 5CDEA 4B28A 4U76A 3MATA 4FUKA 2GG2A 4IF7A 2B3KA 3CB5A 1Y1NA 2BWSA 2BHBA 2Q92A 2BWYA 2GA2A 3PKAA 3TB5A 2BH3A 2BHCA 4RGZ1 4PNCA 1B59A 3FMQA 1YJ3A 2EA2A 2GGCA 1WL6A 3IG4A 4U69A 2BN7A 1B6AA 4S00A 3RVAA 4IPAA 2EVCA 1WY2A 5JFRA 3MX6A 1YW8A 1XNZA 3L7GA 2Q94A 2B3LA 4FLLA 4U75A 1YW9A 1WKMA 2DFIA 4IU6A 4JUQA 4U6JA 2GU5A 3FM3A 2BB7A 3CB6A 3IU9A 2GTXA 1BN5A 1C27A 2ZSGA 2V3YA 4U6CA 3MR1A 4U1BA 4FO8A 2MATA 4S01A 5CIKA 5D6FA 5CDVA 5E5BA 2BWWA 2IW2A 2P9AA 4FLKA 2EVOA 2NQ7A 5CE6A 1C21A 5JI6A 1R5GA 2V3XA 3FMRA 1R5HA 1PV9A 4U6WA 2BHDA 1XGSA
chains in the Genus database with same CATH superfamily
4KM3A 2Q93A 4FLJA 4ZWPA 3TAVA 1WBQA 4ZWOA 4A6VA 1CHMA 2Q96A 4S2TP 4EGEA 2GU4A 1A16A 1WN1A 1XGMA 1KQ0A 3BITA 2BWVA 5D6EA 4IKUA 1W7VA 1JAWA 3BIPA 3L24A 2BHAA 4IECA 1KP0A 1R58A 4FLIA 1M35A 4U73A 1QXWA 1XGOA 2P99A 3IU8A 4ZWUA 2GG0A 2NQ6A 2GG9A 2P98A 4OOKA 2EA4A 2GU6A 2HOWA 1BOAA 1XGNA 3IU7A 4IKTA 2GG3A 5FCFA 3S6BA 2BWXA 2V6CA 5CNXA 5CDLA 1QXYA 1QZYA 1O0XA 1WL9A 3D27A 4RZZA 4RZYA 1MATA 2GG7A 1YW7A 2GU7A 4QR8A 5CLSA 2GGBA 1C22A 4IKSA 1KQ9A 2ADUA 4IDYA 4U6EA 4Z7MA 2G6PA 2GZ5A 5FCHA 2Q8KA 3PKDA 3RORA 2B3HA 1WLRA 4U70A 4U71A 3BIQA 4A6WA 2GG5A 3PKCA 4FKCA 3PKBA 1W2MA 1C24A 1YVMA 4IKRA 1N51A 2BWTA 1C23A 4FO7A 2EVMA 2OAZA 4MATA 2V3ZA 2BWUA 3PKEA 2Q95A 2OKNA 3Q6DA 4PV4A 2GG8A 4S2RP 4R60A 5JHUA 4U6ZA 4ZNGA 3CTZA 1QXZA 4HXXA 5CDEA 4B28A 4U76A 3MATA 4FUKA 2GG2A 4IF7A 2B3KA 3CB5A 1Y1NA 2BWSA 2BHBA 2Q92A 2BWYA 2GA2A 3PKAA 3TB5A 2BH3A 2BHCA 4RGZ1 4PNCA 1B59A 3FMQA 1YJ3A 2EA2A 2GGCA 1WL6A 3IG4A 4U69A 2BN7A 1B6AA 4S00A 3RVAA 4IPAA 2EVCA 1WY2A 5JFRA 3MX6A 1YW8A 1XNZA 3L7GA 2Q94A 2B3LA 4FLLA 4U75A 1YW9A 1WKMA 2DFIA 4IU6A 4JUQA 4U6JA 2GU5A 3FM3A 2BB7A 3CB6A 3IU9A 2GTXA 1BN5A 1C27A 2ZSGA 2V3YA 4U6CA 3MR1A 4U1BA 4FO8A 2MATA 4S01A 5CIKA 5D6FA 5CDVA 5E5BA 2BWWA 2IW2A 2P9AA 4FLKA 2EVOA 2NQ7A 5CE6A 1C21A 5JI6A 1R5GA 2V3XA 3FMRA 1R5HA 1PV9A 4U6WA 2BHDA 1XGSA
chains in the Genus database with same CATH topology
4KM3A 2Q93A 4FLJA 4ZWPA 3TAVA 1WBQA 4ZWOA 4A6VA 1CHMA 2Q96A 4S2TP 4EGEA 2GU4A 1A16A 1WN1A 1XGMA 1KQ0A 3BITA 2BWVA 5D6EA 4IKUA 1W7VA 1JAWA 3BIPA 3L24A 2BHAA 4IECA 1KP0A 1R58A 4FLIA 1M35A 4U73A 1QXWA 1XGOA 2P99A 3IU8A 4ZWUA 2GG0A 2NQ6A 2GG9A 2P98A 4OOKA 2EA4A 2GU6A 2HOWA 1BOAA 1XGNA 3IU7A 4IKTA 2GG3A 5FCFA 3S6BA 2BWXA 2V6CA 5CNXA 5CDLA 1QXYA 1QZYA 1O0XA 1WL9A 3D27A 4RZZA 4RZYA 1MATA 2GG7A 1YW7A 2GU7A 4QR8A 5CLSA 2GGBA 1C22A 4IKSA 1KQ9A 2ADUA 4IDYA 4U6EA 4Z7MA 2G6PA 2GZ5A 5FCHA 2Q8KA 3PKDA 3RORA 2B3HA 1WLRA 4U70A 4U71A 3BIQA 4A6WA 2GG5A 3PKCA 4FKCA 3PKBA 1W2MA 1C24A 1YVMA 4IKRA 1N51A 2BWTA 1C23A 4FO7A 2EVMA 2OAZA 4MATA 2V3ZA 2BWUA 3PKEA 2Q95A 2OKNA 3Q6DA 4PV4A 2GG8A 4S2RP 4R60A 5JHUA 4U6ZA 4ZNGA 3CTZA 1QXZA 4HXXA 5CDEA 4B28A 4U76A 3MATA 4FUKA 2GG2A 4IF7A 2B3KA 3CB5A 1Y1NA 2BWSA 2BHBA 2Q92A 2BWYA 2GA2A 3PKAA 3TB5A 2BH3A 2BHCA 4RGZ1 4PNCA 1B59A 3FMQA 1YJ3A 2EA2A 2GGCA 1WL6A 3IG4A 4U69A 2BN7A 1B6AA 4S00A 3RVAA 4IPAA 2EVCA 1WY2A 5JFRA 3MX6A 1YW8A 1XNZA 3L7GA 2Q94A 2B3LA 4FLLA 4U75A 1YW9A 1WKMA 2DFIA 4IU6A 4JUQA 4U6JA 2GU5A 3FM3A 2BB7A 3CB6A 3IU9A 2GTXA 1BN5A 1C27A 2ZSGA 2V3YA 4U6CA 3MR1A 4U1BA 4FO8A 2MATA 4S01A 5CIKA 5D6FA 5CDVA 5E5BA 2BWWA 2IW2A 2P9AA 4FLKA 2EVOA 2NQ7A 5CE6A 1C21A 5JI6A 1R5GA 2V3XA 3FMRA 1R5HA 1PV9A 4U6WA 2BHDA 1XGSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4KM3 A;  2Q93 A;  4FLJ A;  4ZWP A;  3TAV A;  1WBQ A;  4ZWO A;  4A6V A;  1CHM A;  2Q96 A;  4S2T P;  4EGE A;  2GU4 A;  1A16 A;  1WN1 A;  1XGM A;  1KQ0 A;  3BIT A;  2BWV A;  5D6E A;  4IKU A;  1W7V A;  1JAW A;  3BIP A;  3L24 A;  2BHA A;  4IEC A;  1KP0 A;  1R58 A;  4FLI A;  1M35 A;  4U73 A;  1QXW A;  1XGO A;  2P99 A;  3IU8 A;  4ZWU A;  2GG0 A;  2NQ6 A;  2GG9 A;  2P98 A;  4OOK A;  2EA4 A;  2GU6 A;  2HOW A;  1BOA A;  1XGN A;  3IU7 A;  4IKT A;  2GG3 A;  5FCF A;  3S6B A;  2BWX A;  2V6C A;  5CNX A;  5CDL A;  1QXY A;  1QZY A;  1O0X A;  1WL9 A;  3D27 A;  4RZZ A;  4RZY A;  1MAT A;  2GG7 A;  1YW7 A;  2GU7 A;  4QR8 A;  5CLS A;  2GGB A;  1C22 A;  4IKS A;  1KQ9 A;  2ADU A;  4IDY A;  4U6E A;  4Z7M A;  2G6P A;  2GZ5 A;  5FCH A;  2Q8K A;  3PKD A;  3ROR A;  2B3H A;  1WLR A;  4U70 A;  4U71 A;  3BIQ A;  4A6W A;  2GG5 A;  3PKC A;  4FKC A;  3PKB A;  1W2M A;  1C24 A;  1YVM A;  4IKR A;  1N51 A;  2BWT A;  1C23 A;  4FO7 A;  2EVM A;  2OAZ A;  4MAT A;  2V3Z A;  2BWU A;  3PKE A;  2Q95 A;  2OKN A;  3Q6D A;  4PV4 A;  2GG8 A;  4S2R P;  4R60 A;  5JHU A;  4U6Z A;  4ZNG A;  3CTZ A;  1QXZ A;  4HXX A;  5CDE A;  4B28 A;  4U76 A;  3MAT A;  4FUK A;  2GG2 A;  4IF7 A;  2B3K A;  3CB5 A;  1Y1N A;  2BWS A;  2BHB A;  2Q92 A;  2BWY A;  2GA2 A;  3PKA A;  3TB5 A;  2BH3 A;  2BHC A;  4RGZ 1;  4PNC A;  1B59 A;  3FMQ A;  1YJ3 A;  2EA2 A;  2GGC A;  1WL6 A;  3IG4 A;  4U69 A;  2BN7 A;  1B6A A;  4S00 A;  3RVA A;  4IPA A;  2EVC A;  1WY2 A;  5JFR A;  3MX6 A;  1YW8 A;  1XNZ A;  3L7G A;  2Q94 A;  2B3L A;  4FLL A;  4U75 A;  1YW9 A;  1WKM A;  2DFI A;  4IU6 A;  4JUQ A;  4U6J A;  2GU5 A;  3FM3 A;  2BB7 A;  3CB6 A;  3IU9 A;  2GTX A;  1BN5 A;  1C27 A;  2ZSG A;  2V3Y A;  4U6C A;  3MR1 A;  4U1B A;  4FO8 A;  2MAT A;  4S01 A;  5CIK A;  5D6F A;  5CDV A;  5E5B A;  2BWW A;  2IW2 A;  2P9A A;  4FLK A;  2EVO A;  2NQ7 A;  5CE6 A;  1C21 A;  5JI6 A;  1R5G A;  2V3X A;  3FMR A;  1R5H A;  1PV9 A;  4U6W A;  2BHD A;  1XGS A; 
#chains in the Genus database with same CATH topology
 4KM3 A;  2Q93 A;  4FLJ A;  4ZWP A;  3TAV A;  1WBQ A;  4ZWO A;  4A6V A;  1CHM A;  2Q96 A;  4S2T P;  4EGE A;  2GU4 A;  1A16 A;  1WN1 A;  1XGM A;  1KQ0 A;  3BIT A;  2BWV A;  5D6E A;  4IKU A;  1W7V A;  1JAW A;  3BIP A;  3L24 A;  2BHA A;  4IEC A;  1KP0 A;  1R58 A;  4FLI A;  1M35 A;  4U73 A;  1QXW A;  1XGO A;  2P99 A;  3IU8 A;  4ZWU A;  2GG0 A;  2NQ6 A;  2GG9 A;  2P98 A;  4OOK A;  2EA4 A;  2GU6 A;  2HOW A;  1BOA A;  1XGN A;  3IU7 A;  4IKT A;  2GG3 A;  5FCF A;  3S6B A;  2BWX A;  2V6C A;  5CNX A;  5CDL A;  1QXY A;  1QZY A;  1O0X A;  1WL9 A;  3D27 A;  4RZZ A;  4RZY A;  1MAT A;  2GG7 A;  1YW7 A;  2GU7 A;  4QR8 A;  5CLS A;  2GGB A;  1C22 A;  4IKS A;  1KQ9 A;  2ADU A;  4IDY A;  4U6E A;  4Z7M A;  2G6P A;  2GZ5 A;  5FCH A;  2Q8K A;  3PKD A;  3ROR A;  2B3H A;  1WLR A;  4U70 A;  4U71 A;  3BIQ A;  4A6W A;  2GG5 A;  3PKC A;  4FKC A;  3PKB A;  1W2M A;  1C24 A;  1YVM A;  4IKR A;  1N51 A;  2BWT A;  1C23 A;  4FO7 A;  2EVM A;  2OAZ A;  4MAT A;  2V3Z A;  2BWU A;  3PKE A;  2Q95 A;  2OKN A;  3Q6D A;  4PV4 A;  2GG8 A;  4S2R P;  4R60 A;  5JHU A;  4U6Z A;  4ZNG A;  3CTZ A;  1QXZ A;  4HXX A;  5CDE A;  4B28 A;  4U76 A;  3MAT A;  4FUK A;  2GG2 A;  4IF7 A;  2B3K A;  3CB5 A;  1Y1N A;  2BWS A;  2BHB A;  2Q92 A;  2BWY A;  2GA2 A;  3PKA A;  3TB5 A;  2BH3 A;  2BHC A;  4RGZ 1;  4PNC A;  1B59 A;  3FMQ A;  1YJ3 A;  2EA2 A;  2GGC A;  1WL6 A;  3IG4 A;  4U69 A;  2BN7 A;  1B6A A;  4S00 A;  3RVA A;  4IPA A;  2EVC A;  1WY2 A;  5JFR A;  3MX6 A;  1YW8 A;  1XNZ A;  3L7G A;  2Q94 A;  2B3L A;  4FLL A;  4U75 A;  1YW9 A;  1WKM A;  2DFI A;  4IU6 A;  4JUQ A;  4U6J A;  2GU5 A;  3FM3 A;  2BB7 A;  3CB6 A;  3IU9 A;  2GTX A;  1BN5 A;  1C27 A;  2ZSG A;  2V3Y A;  4U6C A;  3MR1 A;  4U1B A;  4FO8 A;  2MAT A;  4S01 A;  5CIK A;  5D6F A;  5CDV A;  5E5B A;  2BWW A;  2IW2 A;  2P9A A;  4FLK A;  2EVO A;  2NQ7 A;  5CE6 A;  1C21 A;  5JI6 A;  1R5G A;  2V3X A;  3FMR A;  1R5H A;  1PV9 A;  4U6W A;  2BHD A;  1XGS A; 
#chains in the Genus database with same CATH homology
 4KM3 A;  2Q93 A;  4FLJ A;  4ZWP A;  3TAV A;  1WBQ A;  4ZWO A;  4A6V A;  1CHM A;  2Q96 A;  4S2T P;  4EGE A;  2GU4 A;  1A16 A;  1WN1 A;  1XGM A;  1KQ0 A;  3BIT A;  2BWV A;  5D6E A;  4IKU A;  1W7V A;  1JAW A;  3BIP A;  3L24 A;  2BHA A;  4IEC A;  1KP0 A;  1R58 A;  4FLI A;  1M35 A;  4U73 A;  1QXW A;  1XGO A;  2P99 A;  3IU8 A;  4ZWU A;  2GG0 A;  2NQ6 A;  2GG9 A;  2P98 A;  4OOK A;  2EA4 A;  2GU6 A;  2HOW A;  1BOA A;  1XGN A;  3IU7 A;  4IKT A;  2GG3 A;  5FCF A;  3S6B A;  2BWX A;  2V6C A;  5CNX A;  5CDL A;  1QXY A;  1QZY A;  1O0X A;  1WL9 A;  3D27 A;  4RZZ A;  4RZY A;  1MAT A;  2GG7 A;  1YW7 A;  2GU7 A;  4QR8 A;  5CLS A;  2GGB A;  1C22 A;  4IKS A;  1KQ9 A;  2ADU A;  4IDY A;  4U6E A;  4Z7M A;  2G6P A;  2GZ5 A;  5FCH A;  2Q8K A;  3PKD A;  3ROR A;  2B3H A;  1WLR A;  4U70 A;  4U71 A;  3BIQ A;  4A6W A;  2GG5 A;  3PKC A;  4FKC A;  3PKB A;  1W2M A;  1C24 A;  1YVM A;  4IKR A;  1N51 A;  2BWT A;  1C23 A;  4FO7 A;  2EVM A;  2OAZ A;  4MAT A;  2V3Z A;  2BWU A;  3PKE A;  2Q95 A;  2OKN A;  3Q6D A;  4PV4 A;  2GG8 A;  4S2R P;  4R60 A;  5JHU A;  4U6Z A;  4ZNG A;  3CTZ A;  1QXZ A;  4HXX A;  5CDE A;  4B28 A;  4U76 A;  3MAT A;  4FUK A;  2GG2 A;  4IF7 A;  2B3K A;  3CB5 A;  1Y1N A;  2BWS A;  2BHB A;  2Q92 A;  2BWY A;  2GA2 A;  3PKA A;  3TB5 A;  2BH3 A;  2BHC A;  4RGZ 1;  4PNC A;  1B59 A;  3FMQ A;  1YJ3 A;  2EA2 A;  2GGC A;  1WL6 A;  3IG4 A;  4U69 A;  2BN7 A;  1B6A A;  4S00 A;  3RVA A;  4IPA A;  2EVC A;  1WY2 A;  5JFR A;  3MX6 A;  1YW8 A;  1XNZ A;  3L7G A;  2Q94 A;  2B3L A;  4FLL A;  4U75 A;  1YW9 A;  1WKM A;  2DFI A;  4IU6 A;  4JUQ A;  4U6J A;  2GU5 A;  3FM3 A;  2BB7 A;  3CB6 A;  3IU9 A;  2GTX A;  1BN5 A;  1C27 A;  2ZSG A;  2V3Y A;  4U6C A;  3MR1 A;  4U1B A;  4FO8 A;  2MAT A;  4S01 A;  5CIK A;  5D6F A;  5CDV A;  5E5B A;  2BWW A;  2IW2 A;  2P9A A;  4FLK A;  2EVO A;  2NQ7 A;  5CE6 A;  1C21 A;  5JI6 A;  1R5G A;  2V3X A;  3FMR A;  1R5H A;  1PV9 A;  4U6W A;  2BHD A;  1XGS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
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#similar chains, but unknotted
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