3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
b'PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
4U76A 1XGOA 2GU6A 2V6CA 4U70A 1YVMA 3D27A 3PKAA 2BH3A 2Q95A 1XGNA 1XGSA 2BN7A 4JUQA 1BN5A 4RZYA 5JHUA 4U6ZA 4PV4A 1A16A 4FKCA 3PKBA 4FUKA 4U75A 2BHDA 1R5HA 1XNZA 2GU5A 2G6PA 1B6AA 2GU4A 2OAZA 2GZ5A 1YW8A 4RZZA 2BWSA 2EVCA 5CDEA 1C21A 1C24A 3IU7A 4FO7A 4U69A 1C27A 4U73A 2GG3A 1KQ9A 4U1BA 5FCFA 5D6EA 3TB5A 4S2RP 4OOKA 1WL6A 4U6EA 2V3YA 3IU8A 2B3KA 2MATA 1BOAA 4U6JA 1CHMA 3FM3A 4ZNGA 4U6WA 4PNCA 1YJ3A 4R60A 4FLJA 2OKNA 3BIQA 2GGBA 3MX6A 2HOWA 2NQ6A 1R58A 2IW2A 2GA2A 4FLLA 2ZSGA 2Q93A 3BIPA 4IKTA 5CDVA 2EA4A 1WBQA 3L7GA 3Q6DA 4FO8A 1Y1NA 2Q96A 1PV9A 1R5GA 2BHAA 3CTZA 4S00A 3BITA 4MATA 5CDLA 1WLRA 1C23A 4IECA 4EGEA 2GGCA 4HXXA 5CLSA 3PKEA 4A6WA 5D6FA 3L24A 5CE6A 3FMRA 4S2TP 3RVAA 2B3LA 2BWWA 1WN1A 4S01A 4ZWPA 4A6VA 3CB6A 4B28A 2BWYA 5E5BA 1YW9A 1N51A 2BWXA 3RORA 4ZWUA 2BB7A 5JI6A 2GG0A 4IDYA 3MATA 2BHBA 2GG8A 2P99A 2Q94A 1QZYA 2P9AA 5CIKA 1QXYA 5CNXA 4Z7MA 2DFIA 2BHCA 2GU7A 2BWTA 3S6BA 2V3XA 4IKUA 1O0XA 1WKMA 2EVMA 2NQ7A 2P98A 1XGMA 1QXWA 5JFRA 1W2MA 4QR8A 3FMQA 2Q8KA 1JAWA 3CB5A 4FLIA 3IU9A 2EA2A 2GTXA 2GG2A 1MATA 2Q92A 4IPAA 4KM3A 3MR1A 2B3HA 2GG9A 1KQ0A 4RGZ1 2BWVA 1WL9A 4IU6A 1W7VA 3PKCA 5FCHA 4U71A 3TAVA 2EVOA 3IG4A 2GG5A 4IKRA 4ZWOA 4U6CA 4IF7A 1QXZA 1C22A 2GG7A 2BWUA 4IKSA 1B59A 1YW7A 4FLKA 1KP0A 1WY2A 3PKDA 2ADUA 2V3ZA 1M35A
chains in the Genus database with same CATH superfamily
4U76A 1XGOA 2GU6A 2V6CA 4U70A 1YVMA 3D27A 3PKAA 2BH3A 2Q95A 1XGNA 1XGSA 2BN7A 4JUQA 1BN5A 4RZYA 5JHUA 4U6ZA 4PV4A 1A16A 4FKCA 3PKBA 4FUKA 4U75A 2BHDA 1R5HA 1XNZA 2GU5A 2G6PA 1B6AA 2GU4A 2OAZA 2GZ5A 1YW8A 4RZZA 2BWSA 2EVCA 5CDEA 1C21A 1C24A 3IU7A 4FO7A 4U69A 1C27A 4U73A 2GG3A 1KQ9A 4U1BA 5FCFA 5D6EA 3TB5A 4S2RP 4OOKA 1WL6A 4U6EA 2V3YA 3IU8A 2B3KA 2MATA 1BOAA 4U6JA 1CHMA 3FM3A 4ZNGA 4U6WA 4PNCA 1YJ3A 4R60A 4FLJA 2OKNA 3BIQA 2GGBA 3MX6A 2HOWA 2NQ6A 1R58A 2IW2A 2GA2A 4FLLA 2ZSGA 2Q93A 3BIPA 4IKTA 5CDVA 2EA4A 1WBQA 3L7GA 3Q6DA 4FO8A 1Y1NA 2Q96A 1PV9A 1R5GA 2BHAA 3CTZA 4S00A 3BITA 4MATA 5CDLA 1WLRA 1C23A 4IECA 4EGEA 2GGCA 4HXXA 5CLSA 3PKEA 4A6WA 5D6FA 3L24A 5CE6A 3FMRA 4S2TP 3RVAA 2B3LA 2BWWA 1WN1A 4S01A 4ZWPA 4A6VA 3CB6A 4B28A 2BWYA 5E5BA 1YW9A 1N51A 2BWXA 3RORA 4ZWUA 2BB7A 5JI6A 2GG0A 4IDYA 3MATA 2BHBA 2GG8A 2P99A 2Q94A 1QZYA 2P9AA 5CIKA 1QXYA 5CNXA 4Z7MA 2DFIA 2BHCA 2GU7A 2BWTA 3S6BA 2V3XA 4IKUA 1O0XA 1WKMA 2EVMA 2NQ7A 2P98A 1XGMA 1QXWA 5JFRA 1W2MA 4QR8A 3FMQA 2Q8KA 1JAWA 3CB5A 4FLIA 3IU9A 2EA2A 2GTXA 2GG2A 1MATA 2Q92A 4IPAA 4KM3A 3MR1A 2B3HA 2GG9A 1KQ0A 4RGZ1 2BWVA 1WL9A 4IU6A 1W7VA 3PKCA 5FCHA 4U71A 3TAVA 2EVOA 3IG4A 2GG5A 4IKRA 4ZWOA 4U6CA 4IF7A 1QXZA 1C22A 2GG7A 2BWUA 4IKSA 1B59A 1YW7A 4FLKA 1KP0A 1WY2A 3PKDA 2ADUA 2V3ZA 1M35A
chains in the Genus database with same CATH topology
4U76A 1XGOA 2GU6A 2V6CA 4U70A 1YVMA 3D27A 3PKAA 2BH3A 2Q95A 1XGNA 1XGSA 2BN7A 4JUQA 1BN5A 4RZYA 5JHUA 4U6ZA 4PV4A 1A16A 4FKCA 3PKBA 4FUKA 4U75A 2BHDA 1R5HA 1XNZA 2GU5A 2G6PA 1B6AA 2GU4A 2OAZA 2GZ5A 1YW8A 4RZZA 2BWSA 2EVCA 5CDEA 1C21A 1C24A 3IU7A 4FO7A 4U69A 1C27A 4U73A 2GG3A 1KQ9A 4U1BA 5FCFA 5D6EA 3TB5A 4S2RP 4OOKA 1WL6A 4U6EA 2V3YA 3IU8A 2B3KA 2MATA 1BOAA 4U6JA 1CHMA 3FM3A 4ZNGA 4U6WA 4PNCA 1YJ3A 4R60A 4FLJA 2OKNA 3BIQA 2GGBA 3MX6A 2HOWA 2NQ6A 1R58A 2IW2A 2GA2A 4FLLA 2ZSGA 2Q93A 3BIPA 4IKTA 5CDVA 2EA4A 1WBQA 3L7GA 3Q6DA 4FO8A 1Y1NA 2Q96A 1PV9A 1R5GA 2BHAA 3CTZA 4S00A 3BITA 4MATA 5CDLA 1WLRA 1C23A 4IECA 4EGEA 2GGCA 4HXXA 5CLSA 3PKEA 4A6WA 5D6FA 3L24A 5CE6A 3FMRA 4S2TP 3RVAA 2B3LA 2BWWA 1WN1A 4S01A 4ZWPA 4A6VA 3CB6A 4B28A 2BWYA 5E5BA 1YW9A 1N51A 2BWXA 3RORA 4ZWUA 2BB7A 5JI6A 2GG0A 4IDYA 3MATA 2BHBA 2GG8A 2P99A 2Q94A 1QZYA 2P9AA 5CIKA 1QXYA 5CNXA 4Z7MA 2DFIA 2BHCA 2GU7A 2BWTA 3S6BA 2V3XA 4IKUA 1O0XA 1WKMA 2EVMA 2NQ7A 2P98A 1XGMA 1QXWA 5JFRA 1W2MA 4QR8A 3FMQA 2Q8KA 1JAWA 3CB5A 4FLIA 3IU9A 2EA2A 2GTXA 2GG2A 1MATA 2Q92A 4IPAA 4KM3A 3MR1A 2B3HA 2GG9A 1KQ0A 4RGZ1 2BWVA 1WL9A 4IU6A 1W7VA 3PKCA 5FCHA 4U71A 3TAVA 2EVOA 3IG4A 2GG5A 4IKRA 4ZWOA 4U6CA 4IF7A 1QXZA 1C22A 2GG7A 2BWUA 4IKSA 1B59A 1YW7A 4FLKA 1KP0A 1WY2A 3PKDA 2ADUA 2V3ZA 1M35A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U76 A;  1XGO A;  2GU6 A;  2V6C A;  4U70 A;  1YVM A;  3D27 A;  3PKA A;  2BH3 A;  2Q95 A;  1XGN A;  1XGS A;  2BN7 A;  4JUQ A;  1BN5 A;  4RZY A;  5JHU A;  4U6Z A;  4PV4 A;  1A16 A;  4FKC A;  3PKB A;  4FUK A;  4U75 A;  2BHD A;  1R5H A;  1XNZ A;  2GU5 A;  2G6P A;  1B6A A;  2GU4 A;  2OAZ A;  2GZ5 A;  1YW8 A;  4RZZ A;  2BWS A;  2EVC A;  5CDE A;  1C21 A;  1C24 A;  3IU7 A;  4FO7 A;  4U69 A;  1C27 A;  4U73 A;  2GG3 A;  1KQ9 A;  4U1B A;  5FCF A;  5D6E A;  3TB5 A;  4S2R P;  4OOK A;  1WL6 A;  4U6E A;  2V3Y A;  3IU8 A;  2B3K A;  2MAT A;  1BOA A;  4U6J A;  1CHM A;  3FM3 A;  4ZNG A;  4U6W A;  4PNC A;  1YJ3 A;  4R60 A;  4FLJ A;  2OKN A;  3BIQ A;  2GGB A;  3MX6 A;  2HOW A;  2NQ6 A;  1R58 A;  2IW2 A;  2GA2 A;  4FLL A;  2ZSG A;  2Q93 A;  3BIP A;  4IKT A;  5CDV A;  2EA4 A;  1WBQ A;  3L7G A;  3Q6D A;  4FO8 A;  1Y1N A;  2Q96 A;  1PV9 A;  1R5G A;  2BHA A;  3CTZ A;  4S00 A;  3BIT A;  4MAT A;  5CDL A;  1WLR A;  1C23 A;  4IEC A;  4EGE A;  2GGC A;  4HXX A;  5CLS A;  3PKE A;  4A6W A;  5D6F A;  3L24 A;  5CE6 A;  3FMR A;  4S2T P;  3RVA A;  2B3L A;  2BWW A;  1WN1 A;  4S01 A;  4ZWP A;  4A6V A;  3CB6 A;  4B28 A;  2BWY A;  5E5B A;  1YW9 A;  1N51 A;  2BWX A;  3ROR A;  4ZWU A;  2BB7 A;  5JI6 A;  2GG0 A;  4IDY A;  3MAT A;  2BHB A;  2GG8 A;  2P99 A;  2Q94 A;  1QZY A;  2P9A A;  5CIK A;  1QXY A;  5CNX A;  4Z7M A;  2DFI A;  2BHC A;  2GU7 A;  2BWT A;  3S6B A;  2V3X A;  4IKU A;  1O0X A;  1WKM A;  2EVM A;  2NQ7 A;  2P98 A;  1XGM A;  1QXW A;  5JFR A;  1W2M A;  4QR8 A;  3FMQ A;  2Q8K A;  1JAW A;  3CB5 A;  4FLI A;  3IU9 A;  2EA2 A;  2GTX A;  2GG2 A;  1MAT A;  2Q92 A;  4IPA A;  4KM3 A;  3MR1 A;  2B3H A;  2GG9 A;  1KQ0 A;  4RGZ 1;  2BWV A;  1WL9 A;  4IU6 A;  1W7V A;  3PKC A;  5FCH A;  4U71 A;  3TAV A;  2EVO A;  3IG4 A;  2GG5 A;  4IKR A;  4ZWO A;  4U6C A;  4IF7 A;  1QXZ A;  1C22 A;  2GG7 A;  2BWU A;  4IKS A;  1B59 A;  1YW7 A;  4FLK A;  1KP0 A;  1WY2 A;  3PKD A;  2ADU A;  2V3Z A;  1M35 A; 
#chains in the Genus database with same CATH topology
 4U76 A;  1XGO A;  2GU6 A;  2V6C A;  4U70 A;  1YVM A;  3D27 A;  3PKA A;  2BH3 A;  2Q95 A;  1XGN A;  1XGS A;  2BN7 A;  4JUQ A;  1BN5 A;  4RZY A;  5JHU A;  4U6Z A;  4PV4 A;  1A16 A;  4FKC A;  3PKB A;  4FUK A;  4U75 A;  2BHD A;  1R5H A;  1XNZ A;  2GU5 A;  2G6P A;  1B6A A;  2GU4 A;  2OAZ A;  2GZ5 A;  1YW8 A;  4RZZ A;  2BWS A;  2EVC A;  5CDE A;  1C21 A;  1C24 A;  3IU7 A;  4FO7 A;  4U69 A;  1C27 A;  4U73 A;  2GG3 A;  1KQ9 A;  4U1B A;  5FCF A;  5D6E A;  3TB5 A;  4S2R P;  4OOK A;  1WL6 A;  4U6E A;  2V3Y A;  3IU8 A;  2B3K A;  2MAT A;  1BOA A;  4U6J A;  1CHM A;  3FM3 A;  4ZNG A;  4U6W A;  4PNC A;  1YJ3 A;  4R60 A;  4FLJ A;  2OKN A;  3BIQ A;  2GGB A;  3MX6 A;  2HOW A;  2NQ6 A;  1R58 A;  2IW2 A;  2GA2 A;  4FLL A;  2ZSG A;  2Q93 A;  3BIP A;  4IKT A;  5CDV A;  2EA4 A;  1WBQ A;  3L7G A;  3Q6D A;  4FO8 A;  1Y1N A;  2Q96 A;  1PV9 A;  1R5G A;  2BHA A;  3CTZ A;  4S00 A;  3BIT A;  4MAT A;  5CDL A;  1WLR A;  1C23 A;  4IEC A;  4EGE A;  2GGC A;  4HXX A;  5CLS A;  3PKE A;  4A6W A;  5D6F A;  3L24 A;  5CE6 A;  3FMR A;  4S2T P;  3RVA A;  2B3L A;  2BWW A;  1WN1 A;  4S01 A;  4ZWP A;  4A6V A;  3CB6 A;  4B28 A;  2BWY A;  5E5B A;  1YW9 A;  1N51 A;  2BWX A;  3ROR A;  4ZWU A;  2BB7 A;  5JI6 A;  2GG0 A;  4IDY A;  3MAT A;  2BHB A;  2GG8 A;  2P99 A;  2Q94 A;  1QZY A;  2P9A A;  5CIK A;  1QXY A;  5CNX A;  4Z7M A;  2DFI A;  2BHC A;  2GU7 A;  2BWT A;  3S6B A;  2V3X A;  4IKU A;  1O0X A;  1WKM A;  2EVM A;  2NQ7 A;  2P98 A;  1XGM A;  1QXW A;  5JFR A;  1W2M A;  4QR8 A;  3FMQ A;  2Q8K A;  1JAW A;  3CB5 A;  4FLI A;  3IU9 A;  2EA2 A;  2GTX A;  2GG2 A;  1MAT A;  2Q92 A;  4IPA A;  4KM3 A;  3MR1 A;  2B3H A;  2GG9 A;  1KQ0 A;  4RGZ 1;  2BWV A;  1WL9 A;  4IU6 A;  1W7V A;  3PKC A;  5FCH A;  4U71 A;  3TAV A;  2EVO A;  3IG4 A;  2GG5 A;  4IKR A;  4ZWO A;  4U6C A;  4IF7 A;  1QXZ A;  1C22 A;  2GG7 A;  2BWU A;  4IKS A;  1B59 A;  1YW7 A;  4FLK A;  1KP0 A;  1WY2 A;  3PKD A;  2ADU A;  2V3Z A;  1M35 A; 
#chains in the Genus database with same CATH homology
 4U76 A;  1XGO A;  2GU6 A;  2V6C A;  4U70 A;  1YVM A;  3D27 A;  3PKA A;  2BH3 A;  2Q95 A;  1XGN A;  1XGS A;  2BN7 A;  4JUQ A;  1BN5 A;  4RZY A;  5JHU A;  4U6Z A;  4PV4 A;  1A16 A;  4FKC A;  3PKB A;  4FUK A;  4U75 A;  2BHD A;  1R5H A;  1XNZ A;  2GU5 A;  2G6P A;  1B6A A;  2GU4 A;  2OAZ A;  2GZ5 A;  1YW8 A;  4RZZ A;  2BWS A;  2EVC A;  5CDE A;  1C21 A;  1C24 A;  3IU7 A;  4FO7 A;  4U69 A;  1C27 A;  4U73 A;  2GG3 A;  1KQ9 A;  4U1B A;  5FCF A;  5D6E A;  3TB5 A;  4S2R P;  4OOK A;  1WL6 A;  4U6E A;  2V3Y A;  3IU8 A;  2B3K A;  2MAT A;  1BOA A;  4U6J A;  1CHM A;  3FM3 A;  4ZNG A;  4U6W A;  4PNC A;  1YJ3 A;  4R60 A;  4FLJ A;  2OKN A;  3BIQ A;  2GGB A;  3MX6 A;  2HOW A;  2NQ6 A;  1R58 A;  2IW2 A;  2GA2 A;  4FLL A;  2ZSG A;  2Q93 A;  3BIP A;  4IKT A;  5CDV A;  2EA4 A;  1WBQ A;  3L7G A;  3Q6D A;  4FO8 A;  1Y1N A;  2Q96 A;  1PV9 A;  1R5G A;  2BHA A;  3CTZ A;  4S00 A;  3BIT A;  4MAT A;  5CDL A;  1WLR A;  1C23 A;  4IEC A;  4EGE A;  2GGC A;  4HXX A;  5CLS A;  3PKE A;  4A6W A;  5D6F A;  3L24 A;  5CE6 A;  3FMR A;  4S2T P;  3RVA A;  2B3L A;  2BWW A;  1WN1 A;  4S01 A;  4ZWP A;  4A6V A;  3CB6 A;  4B28 A;  2BWY A;  5E5B A;  1YW9 A;  1N51 A;  2BWX A;  3ROR A;  4ZWU A;  2BB7 A;  5JI6 A;  2GG0 A;  4IDY A;  3MAT A;  2BHB A;  2GG8 A;  2P99 A;  2Q94 A;  1QZY A;  2P9A A;  5CIK A;  1QXY A;  5CNX A;  4Z7M A;  2DFI A;  2BHC A;  2GU7 A;  2BWT A;  3S6B A;  2V3X A;  4IKU A;  1O0X A;  1WKM A;  2EVM A;  2NQ7 A;  2P98 A;  1XGM A;  1QXW A;  5JFR A;  1W2M A;  4QR8 A;  3FMQ A;  2Q8K A;  1JAW A;  3CB5 A;  4FLI A;  3IU9 A;  2EA2 A;  2GTX A;  2GG2 A;  1MAT A;  2Q92 A;  4IPA A;  4KM3 A;  3MR1 A;  2B3H A;  2GG9 A;  1KQ0 A;  4RGZ 1;  2BWV A;  1WL9 A;  4IU6 A;  1W7V A;  3PKC A;  5FCH A;  4U71 A;  3TAV A;  2EVO A;  3IG4 A;  2GG5 A;  4IKR A;  4ZWO A;  4U6C A;  4IF7 A;  1QXZ A;  1C22 A;  2GG7 A;  2BWU A;  4IKS A;  1B59 A;  1YW7 A;  4FLK A;  1KP0 A;  1WY2 A;  3PKD A;  2ADU A;  2V3Z A;  1M35 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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