3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
1YVMA 2DFIA 2GU5A 1MATA 2GG2A 3CTZA 4FKCA 5FCHA 4FLIA 2Q94A 1XGOA 2P99A 4FLLA 4U6WA 2P9AA 1YW7A 2BWSA 2EA4A 1C24A 5CDVA 4Z7MA 1C22A 4IKSA 1WL6A 3L7GA 4S2RP 2Q95A 2GA2A 4U76A 1A16A 4PNCA 3RORA 2GG9A 3PKAA 2GG8A 1XGMA 4FO8A 4IDYA 2EVOA 3IU9A 2BWVA 4U75A 2BWWA 5CIKA 2BWXA 4A6VA 2Q93A 2GGBA 3CB5A 1KQ0A 1Y1NA 2GGCA 4IKUA 3PKCA 4U71A 3FM3A 2B3HA 4IPAA 2EVMA 3PKBA 2BB7A 2V3XA 1WKMA 4FO7A 2BWUA 2BHAA 1YJ3A 1YW8A 2BHBA 1C27A 2BHDA 2G6PA 2ADUA 2GG3A 4IF7A 2GG5A 2BN7A 2GG0A 2ZSGA 3PKDA 5D6FA 2GU6A 2BH3A 4FLKA 4FLJA 4U1BA 4U6CA 5FCFA 1B59A 1CHMA 2B3KA 2OAZA 4ZNGA 2BWTA 2OKNA 4JUQA 3BIQA 5JI6A 2Q8KA 1M35A 4PV4A 4FUKA 4S2TP 3IU7A 4U69A 5CLSA 3Q6DA 2GTXA 5CDLA 4R60A 5E5BA 3BIPA 3MATA 4A6WA 1JAWA 1QZYA 2EVCA 1O0XA 1W7VA 4U6EA 1B6AA 1QXZA 3TB5A 4U6ZA 5CNXA 2B3LA 4OOKA 1R5HA 3IG4A 2HOWA 3L24A 2NQ7A 2GU7A 4S00A 1WY2A 4ZWUA 2V3ZA 4S01A 4ZWOA 3PKEA 1WBQA 2BWYA 4RZZA 1YW9A 4EGEA 1BN5A 4RGZ1 3MX6A 1WN1A 2IW2A 1W2MA 1R58A 2NQ6A 4RZYA 4MATA 3MR1A 3FMRA 4U73A 5JHUA 1QXYA 2GZ5A 3FMQA 1KP0A 2V3YA 4IU6A 4U6JA 4B28A 2BHCA 4U70A 1C23A 2P98A 2V6CA 4ZWPA 3IU8A 5CE6A 4HXXA 3TAVA 4IKTA 3D27A 2Q92A 4IKRA 5D6EA 1PV9A 1XNZA 2GU4A 3BITA 2GG7A 2MATA 1XGSA 1QXWA 5CDEA 3S6BA 1WL9A 1KQ9A 1N51A 4IECA 1BOAA 1C21A 1R5GA 4QR8A 2Q96A 2EA2A 3CB6A 1WLRA 5JFRA 1XGNA 4KM3A 3RVAA
chains in the Genus database with same CATH superfamily
1YVMA 2DFIA 2GU5A 1MATA 2GG2A 3CTZA 4FKCA 5FCHA 4FLIA 2Q94A 1XGOA 2P99A 4FLLA 4U6WA 2P9AA 1YW7A 2BWSA 2EA4A 1C24A 5CDVA 4Z7MA 1C22A 4IKSA 1WL6A 3L7GA 4S2RP 2Q95A 2GA2A 4U76A 1A16A 4PNCA 3RORA 2GG9A 3PKAA 2GG8A 1XGMA 4FO8A 4IDYA 2EVOA 3IU9A 2BWVA 4U75A 2BWWA 5CIKA 2BWXA 4A6VA 2Q93A 2GGBA 3CB5A 1KQ0A 1Y1NA 2GGCA 4IKUA 3PKCA 4U71A 3FM3A 2B3HA 4IPAA 2EVMA 3PKBA 2BB7A 2V3XA 1WKMA 4FO7A 2BWUA 2BHAA 1YJ3A 1YW8A 2BHBA 1C27A 2BHDA 2G6PA 2ADUA 2GG3A 4IF7A 2GG5A 2BN7A 2GG0A 2ZSGA 3PKDA 5D6FA 2GU6A 2BH3A 4FLKA 4FLJA 4U1BA 4U6CA 5FCFA 1B59A 1CHMA 2B3KA 2OAZA 4ZNGA 2BWTA 2OKNA 4JUQA 3BIQA 5JI6A 2Q8KA 1M35A 4PV4A 4FUKA 4S2TP 3IU7A 4U69A 5CLSA 3Q6DA 2GTXA 5CDLA 4R60A 5E5BA 3BIPA 3MATA 4A6WA 1JAWA 1QZYA 2EVCA 1O0XA 1W7VA 4U6EA 1B6AA 1QXZA 3TB5A 4U6ZA 5CNXA 2B3LA 4OOKA 1R5HA 3IG4A 2HOWA 3L24A 2NQ7A 2GU7A 4S00A 1WY2A 4ZWUA 2V3ZA 4S01A 4ZWOA 3PKEA 1WBQA 2BWYA 4RZZA 1YW9A 4EGEA 1BN5A 4RGZ1 3MX6A 1WN1A 2IW2A 1W2MA 1R58A 2NQ6A 4RZYA 4MATA 3MR1A 3FMRA 4U73A 5JHUA 1QXYA 2GZ5A 3FMQA 1KP0A 2V3YA 4IU6A 4U6JA 4B28A 2BHCA 4U70A 1C23A 2P98A 2V6CA 4ZWPA 3IU8A 5CE6A 4HXXA 3TAVA 4IKTA 3D27A 2Q92A 4IKRA 5D6EA 1PV9A 1XNZA 2GU4A 3BITA 2GG7A 2MATA 1XGSA 1QXWA 5CDEA 3S6BA 1WL9A 1KQ9A 1N51A 4IECA 1BOAA 1C21A 1R5GA 4QR8A 2Q96A 2EA2A 3CB6A 1WLRA 5JFRA 1XGNA 4KM3A 3RVAA
chains in the Genus database with same CATH topology
1YVMA 2DFIA 2GU5A 1MATA 2GG2A 3CTZA 4FKCA 5FCHA 4FLIA 2Q94A 1XGOA 2P99A 4FLLA 4U6WA 2P9AA 1YW7A 2BWSA 2EA4A 1C24A 5CDVA 4Z7MA 1C22A 4IKSA 1WL6A 3L7GA 4S2RP 2Q95A 2GA2A 4U76A 1A16A 4PNCA 3RORA 2GG9A 3PKAA 2GG8A 1XGMA 4FO8A 4IDYA 2EVOA 3IU9A 2BWVA 4U75A 2BWWA 5CIKA 2BWXA 4A6VA 2Q93A 2GGBA 3CB5A 1KQ0A 1Y1NA 2GGCA 4IKUA 3PKCA 4U71A 3FM3A 2B3HA 4IPAA 2EVMA 3PKBA 2BB7A 2V3XA 1WKMA 4FO7A 2BWUA 2BHAA 1YJ3A 1YW8A 2BHBA 1C27A 2BHDA 2G6PA 2ADUA 2GG3A 4IF7A 2GG5A 2BN7A 2GG0A 2ZSGA 3PKDA 5D6FA 2GU6A 2BH3A 4FLKA 4FLJA 4U1BA 4U6CA 5FCFA 1B59A 1CHMA 2B3KA 2OAZA 4ZNGA 2BWTA 2OKNA 4JUQA 3BIQA 5JI6A 2Q8KA 1M35A 4PV4A 4FUKA 4S2TP 3IU7A 4U69A 5CLSA 3Q6DA 2GTXA 5CDLA 4R60A 5E5BA 3BIPA 3MATA 4A6WA 1JAWA 1QZYA 2EVCA 1O0XA 1W7VA 4U6EA 1B6AA 1QXZA 3TB5A 4U6ZA 5CNXA 2B3LA 4OOKA 1R5HA 3IG4A 2HOWA 3L24A 2NQ7A 2GU7A 4S00A 1WY2A 4ZWUA 2V3ZA 4S01A 4ZWOA 3PKEA 1WBQA 2BWYA 4RZZA 1YW9A 4EGEA 1BN5A 4RGZ1 3MX6A 1WN1A 2IW2A 1W2MA 1R58A 2NQ6A 4RZYA 4MATA 3MR1A 3FMRA 4U73A 5JHUA 1QXYA 2GZ5A 3FMQA 1KP0A 2V3YA 4IU6A 4U6JA 4B28A 2BHCA 4U70A 1C23A 2P98A 2V6CA 4ZWPA 3IU8A 5CE6A 4HXXA 3TAVA 4IKTA 3D27A 2Q92A 4IKRA 5D6EA 1PV9A 1XNZA 2GU4A 3BITA 2GG7A 2MATA 1XGSA 1QXWA 5CDEA 3S6BA 1WL9A 1KQ9A 1N51A 4IECA 1BOAA 1C21A 1R5GA 4QR8A 2Q96A 2EA2A 3CB6A 1WLRA 5JFRA 1XGNA 4KM3A 3RVAA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1YVM A;  2DFI A;  2GU5 A;  1MAT A;  2GG2 A;  3CTZ A;  4FKC A;  5FCH A;  4FLI A;  2Q94 A;  1XGO A;  2P99 A;  4FLL A;  4U6W A;  2P9A A;  1YW7 A;  2BWS A;  2EA4 A;  1C24 A;  5CDV A;  4Z7M A;  1C22 A;  4IKS A;  1WL6 A;  3L7G A;  4S2R P;  2Q95 A;  2GA2 A;  4U76 A;  1A16 A;  4PNC A;  3ROR A;  2GG9 A;  3PKA A;  2GG8 A;  1XGM A;  4FO8 A;  4IDY A;  2EVO A;  3IU9 A;  2BWV A;  4U75 A;  2BWW A;  5CIK A;  2BWX A;  4A6V A;  2Q93 A;  2GGB A;  3CB5 A;  1KQ0 A;  1Y1N A;  2GGC A;  4IKU A;  3PKC A;  4U71 A;  3FM3 A;  2B3H A;  4IPA A;  2EVM A;  3PKB A;  2BB7 A;  2V3X A;  1WKM A;  4FO7 A;  2BWU A;  2BHA A;  1YJ3 A;  1YW8 A;  2BHB A;  1C27 A;  2BHD A;  2G6P A;  2ADU A;  2GG3 A;  4IF7 A;  2GG5 A;  2BN7 A;  2GG0 A;  2ZSG A;  3PKD A;  5D6F A;  2GU6 A;  2BH3 A;  4FLK A;  4FLJ A;  4U1B A;  4U6C A;  5FCF A;  1B59 A;  1CHM A;  2B3K A;  2OAZ A;  4ZNG A;  2BWT A;  2OKN A;  4JUQ A;  3BIQ A;  5JI6 A;  2Q8K A;  1M35 A;  4PV4 A;  4FUK A;  4S2T P;  3IU7 A;  4U69 A;  5CLS A;  3Q6D A;  2GTX A;  5CDL A;  4R60 A;  5E5B A;  3BIP A;  3MAT A;  4A6W A;  1JAW A;  1QZY A;  2EVC A;  1O0X A;  1W7V A;  4U6E A;  1B6A A;  1QXZ A;  3TB5 A;  4U6Z A;  5CNX A;  2B3L A;  4OOK A;  1R5H A;  3IG4 A;  2HOW A;  3L24 A;  2NQ7 A;  2GU7 A;  4S00 A;  1WY2 A;  4ZWU A;  2V3Z A;  4S01 A;  4ZWO A;  3PKE A;  1WBQ A;  2BWY A;  4RZZ A;  1YW9 A;  4EGE A;  1BN5 A;  4RGZ 1;  3MX6 A;  1WN1 A;  2IW2 A;  1W2M A;  1R58 A;  2NQ6 A;  4RZY A;  4MAT A;  3MR1 A;  3FMR A;  4U73 A;  5JHU A;  1QXY A;  2GZ5 A;  3FMQ A;  1KP0 A;  2V3Y A;  4IU6 A;  4U6J A;  4B28 A;  2BHC A;  4U70 A;  1C23 A;  2P98 A;  2V6C A;  4ZWP A;  3IU8 A;  5CE6 A;  4HXX A;  3TAV A;  4IKT A;  3D27 A;  2Q92 A;  4IKR A;  5D6E A;  1PV9 A;  1XNZ A;  2GU4 A;  3BIT A;  2GG7 A;  2MAT A;  1XGS A;  1QXW A;  5CDE A;  3S6B A;  1WL9 A;  1KQ9 A;  1N51 A;  4IEC A;  1BOA A;  1C21 A;  1R5G A;  4QR8 A;  2Q96 A;  2EA2 A;  3CB6 A;  1WLR A;  5JFR A;  1XGN A;  4KM3 A;  3RVA A; 
#chains in the Genus database with same CATH topology
 1YVM A;  2DFI A;  2GU5 A;  1MAT A;  2GG2 A;  3CTZ A;  4FKC A;  5FCH A;  4FLI A;  2Q94 A;  1XGO A;  2P99 A;  4FLL A;  4U6W A;  2P9A A;  1YW7 A;  2BWS A;  2EA4 A;  1C24 A;  5CDV A;  4Z7M A;  1C22 A;  4IKS A;  1WL6 A;  3L7G A;  4S2R P;  2Q95 A;  2GA2 A;  4U76 A;  1A16 A;  4PNC A;  3ROR A;  2GG9 A;  3PKA A;  2GG8 A;  1XGM A;  4FO8 A;  4IDY A;  2EVO A;  3IU9 A;  2BWV A;  4U75 A;  2BWW A;  5CIK A;  2BWX A;  4A6V A;  2Q93 A;  2GGB A;  3CB5 A;  1KQ0 A;  1Y1N A;  2GGC A;  4IKU A;  3PKC A;  4U71 A;  3FM3 A;  2B3H A;  4IPA A;  2EVM A;  3PKB A;  2BB7 A;  2V3X A;  1WKM A;  4FO7 A;  2BWU A;  2BHA A;  1YJ3 A;  1YW8 A;  2BHB A;  1C27 A;  2BHD A;  2G6P A;  2ADU A;  2GG3 A;  4IF7 A;  2GG5 A;  2BN7 A;  2GG0 A;  2ZSG A;  3PKD A;  5D6F A;  2GU6 A;  2BH3 A;  4FLK A;  4FLJ A;  4U1B A;  4U6C A;  5FCF A;  1B59 A;  1CHM A;  2B3K A;  2OAZ A;  4ZNG A;  2BWT A;  2OKN A;  4JUQ A;  3BIQ A;  5JI6 A;  2Q8K A;  1M35 A;  4PV4 A;  4FUK A;  4S2T P;  3IU7 A;  4U69 A;  5CLS A;  3Q6D A;  2GTX A;  5CDL A;  4R60 A;  5E5B A;  3BIP A;  3MAT A;  4A6W A;  1JAW A;  1QZY A;  2EVC A;  1O0X A;  1W7V A;  4U6E A;  1B6A A;  1QXZ A;  3TB5 A;  4U6Z A;  5CNX A;  2B3L A;  4OOK A;  1R5H A;  3IG4 A;  2HOW A;  3L24 A;  2NQ7 A;  2GU7 A;  4S00 A;  1WY2 A;  4ZWU A;  2V3Z A;  4S01 A;  4ZWO A;  3PKE A;  1WBQ A;  2BWY A;  4RZZ A;  1YW9 A;  4EGE A;  1BN5 A;  4RGZ 1;  3MX6 A;  1WN1 A;  2IW2 A;  1W2M A;  1R58 A;  2NQ6 A;  4RZY A;  4MAT A;  3MR1 A;  3FMR A;  4U73 A;  5JHU A;  1QXY A;  2GZ5 A;  3FMQ A;  1KP0 A;  2V3Y A;  4IU6 A;  4U6J A;  4B28 A;  2BHC A;  4U70 A;  1C23 A;  2P98 A;  2V6C A;  4ZWP A;  3IU8 A;  5CE6 A;  4HXX A;  3TAV A;  4IKT A;  3D27 A;  2Q92 A;  4IKR A;  5D6E A;  1PV9 A;  1XNZ A;  2GU4 A;  3BIT A;  2GG7 A;  2MAT A;  1XGS A;  1QXW A;  5CDE A;  3S6B A;  1WL9 A;  1KQ9 A;  1N51 A;  4IEC A;  1BOA A;  1C21 A;  1R5G A;  4QR8 A;  2Q96 A;  2EA2 A;  3CB6 A;  1WLR A;  5JFR A;  1XGN A;  4KM3 A;  3RVA A; 
#chains in the Genus database with same CATH homology
 1YVM A;  2DFI A;  2GU5 A;  1MAT A;  2GG2 A;  3CTZ A;  4FKC A;  5FCH A;  4FLI A;  2Q94 A;  1XGO A;  2P99 A;  4FLL A;  4U6W A;  2P9A A;  1YW7 A;  2BWS A;  2EA4 A;  1C24 A;  5CDV A;  4Z7M A;  1C22 A;  4IKS A;  1WL6 A;  3L7G A;  4S2R P;  2Q95 A;  2GA2 A;  4U76 A;  1A16 A;  4PNC A;  3ROR A;  2GG9 A;  3PKA A;  2GG8 A;  1XGM A;  4FO8 A;  4IDY A;  2EVO A;  3IU9 A;  2BWV A;  4U75 A;  2BWW A;  5CIK A;  2BWX A;  4A6V A;  2Q93 A;  2GGB A;  3CB5 A;  1KQ0 A;  1Y1N A;  2GGC A;  4IKU A;  3PKC A;  4U71 A;  3FM3 A;  2B3H A;  4IPA A;  2EVM A;  3PKB A;  2BB7 A;  2V3X A;  1WKM A;  4FO7 A;  2BWU A;  2BHA A;  1YJ3 A;  1YW8 A;  2BHB A;  1C27 A;  2BHD A;  2G6P A;  2ADU A;  2GG3 A;  4IF7 A;  2GG5 A;  2BN7 A;  2GG0 A;  2ZSG A;  3PKD A;  5D6F A;  2GU6 A;  2BH3 A;  4FLK A;  4FLJ A;  4U1B A;  4U6C A;  5FCF A;  1B59 A;  1CHM A;  2B3K A;  2OAZ A;  4ZNG A;  2BWT A;  2OKN A;  4JUQ A;  3BIQ A;  5JI6 A;  2Q8K A;  1M35 A;  4PV4 A;  4FUK A;  4S2T P;  3IU7 A;  4U69 A;  5CLS A;  3Q6D A;  2GTX A;  5CDL A;  4R60 A;  5E5B A;  3BIP A;  3MAT A;  4A6W A;  1JAW A;  1QZY A;  2EVC A;  1O0X A;  1W7V A;  4U6E A;  1B6A A;  1QXZ A;  3TB5 A;  4U6Z A;  5CNX A;  2B3L A;  4OOK A;  1R5H A;  3IG4 A;  2HOW A;  3L24 A;  2NQ7 A;  2GU7 A;  4S00 A;  1WY2 A;  4ZWU A;  2V3Z A;  4S01 A;  4ZWO A;  3PKE A;  1WBQ A;  2BWY A;  4RZZ A;  1YW9 A;  4EGE A;  1BN5 A;  4RGZ 1;  3MX6 A;  1WN1 A;  2IW2 A;  1W2M A;  1R58 A;  2NQ6 A;  4RZY A;  4MAT A;  3MR1 A;  3FMR A;  4U73 A;  5JHU A;  1QXY A;  2GZ5 A;  3FMQ A;  1KP0 A;  2V3Y A;  4IU6 A;  4U6J A;  4B28 A;  2BHC A;  4U70 A;  1C23 A;  2P98 A;  2V6C A;  4ZWP A;  3IU8 A;  5CE6 A;  4HXX A;  3TAV A;  4IKT A;  3D27 A;  2Q92 A;  4IKR A;  5D6E A;  1PV9 A;  1XNZ A;  2GU4 A;  3BIT A;  2GG7 A;  2MAT A;  1XGS A;  1QXW A;  5CDE A;  3S6B A;  1WL9 A;  1KQ9 A;  1N51 A;  4IEC A;  1BOA A;  1C21 A;  1R5G A;  4QR8 A;  2Q96 A;  2EA2 A;  3CB6 A;  1WLR A;  5JFR A;  1XGN A;  4KM3 A;  3RVA A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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