3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase/hydrolase inhibitor
molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
5CLSA 4IKTA 4ZWOA 4FLKA 2NQ7A 2B3HA 3RORA 2GU6A 2EA2A 1Y1NA 3MR1A 1WY2A 2P99A 3TB5A 2BWTA 4U71A 2NQ6A 5CIKA 1WBQA 2HOWA 1KQ9A 1XNZA 2BWWA 3PKCA 3IU9A 1QXWA 2Q93A 4ZWUA 3BIQA 3S6BA 1C27A 4FLJA 5CDLA 4IKRA 2P9AA 1CHMA 4FKCA 4ZWPA 2Q95A 2GG8A 4S01A 5CE6A 3FM3A 2EVOA 2MATA 2P98A 5FCFA 4OOKA 4IKUA 4RZYA 1B6AA 3L7GA 1XGMA 1PV9A 3FMQA 1KP0A 5D6EA 4FO8A 2GA2A 1R5GA 4IDYA 3CTZA 2BB7A 2GU5A 1C23A 5JFRA 3L24A 2GU7A 2GG0A 3IU8A 4U6CA 2BWYA 2B3KA 2Q8KA 4FO7A 4IKSA 4PNCA 2GG5A 1C21A 4B28A 2IW2A 1M35A 1QZYA 3PKEA 2GGCA 4IF7A 3RVAA 2G6PA 2BH3A 2V3YA 4S00A 4IU6A 4U6ZA 2GG3A 4U6WA 3CB5A 2GZ5A 2Q96A 1JAWA 2Q94A 2GGBA 2BWUA 1O0XA 4S2TP 1YVMA 2GG2A 2GU4A 3IG4A 3D27A 4U70A 1MATA 2BHDA 4JUQA 4RGZ1 2GTXA 1C22A 1WKMA 2OKNA 4PV4A 3BITA 2BWXA 1YW7A 2ZSGA 2V3ZA 3IU7A 2Q92A 3PKAA 1WL6A 4U1BA 1QXZA 2BWSA 4U6JA 2V3XA 2BWVA 4QR8A 2EA4A 1WN1A 2DFIA 3MX6A 4U69A 4U76A 4RZZA 5D6FA 4ZNGA 5CDVA 4IECA 1WL9A 1BN5A 2BHBA 1A16A 2OAZA 4A6WA 3TAVA 1XGOA 3Q6DA 4FUKA 1YJ3A 4Z7MA 1XGSA 3PKDA 1YW9A 2BN7A 2EVCA 4KM3A 1R58A 2GG7A 5E5BA 1WLRA 1BOAA 3FMRA 5CDEA 2EVMA 4A6VA 2BHCA 3MATA 2V6CA 2ADUA 5CNXA 1N51A 4EGEA 1XGNA 1W2MA 4FLLA 4R60A 5JHUA 5FCHA 1B59A 2B3LA 1YW8A 4MATA 1QXYA 3BIPA 3CB6A 4S2RP 3PKBA 4U73A 1C24A 4IPAA 2BHAA 1W7VA 2GG9A 4FLIA 5JI6A 1KQ0A 4HXXA 4U75A 4U6EA 1R5HA
chains in the Genus database with same CATH superfamily
5CLSA 4IKTA 4ZWOA 4FLKA 2NQ7A 2B3HA 3RORA 2GU6A 2EA2A 1Y1NA 3MR1A 1WY2A 2P99A 3TB5A 2BWTA 4U71A 2NQ6A 5CIKA 1WBQA 2HOWA 1KQ9A 1XNZA 2BWWA 3PKCA 3IU9A 1QXWA 2Q93A 4ZWUA 3BIQA 3S6BA 1C27A 4FLJA 5CDLA 4IKRA 2P9AA 1CHMA 4FKCA 4ZWPA 2Q95A 2GG8A 4S01A 5CE6A 3FM3A 2EVOA 2MATA 2P98A 5FCFA 4OOKA 4IKUA 4RZYA 1B6AA 3L7GA 1XGMA 1PV9A 3FMQA 1KP0A 5D6EA 4FO8A 2GA2A 1R5GA 4IDYA 3CTZA 2BB7A 2GU5A 1C23A 5JFRA 3L24A 2GU7A 2GG0A 3IU8A 4U6CA 2BWYA 2B3KA 2Q8KA 4FO7A 4IKSA 4PNCA 2GG5A 1C21A 4B28A 2IW2A 1M35A 1QZYA 3PKEA 2GGCA 4IF7A 3RVAA 2G6PA 2BH3A 2V3YA 4S00A 4IU6A 4U6ZA 2GG3A 4U6WA 3CB5A 2GZ5A 2Q96A 1JAWA 2Q94A 2GGBA 2BWUA 1O0XA 4S2TP 1YVMA 2GG2A 2GU4A 3IG4A 3D27A 4U70A 1MATA 2BHDA 4JUQA 4RGZ1 2GTXA 1C22A 1WKMA 2OKNA 4PV4A 3BITA 2BWXA 1YW7A 2ZSGA 2V3ZA 3IU7A 2Q92A 3PKAA 1WL6A 4U1BA 1QXZA 2BWSA 4U6JA 2V3XA 2BWVA 4QR8A 2EA4A 1WN1A 2DFIA 3MX6A 4U69A 4U76A 4RZZA 5D6FA 4ZNGA 5CDVA 4IECA 1WL9A 1BN5A 2BHBA 1A16A 2OAZA 4A6WA 3TAVA 1XGOA 3Q6DA 4FUKA 1YJ3A 4Z7MA 1XGSA 3PKDA 1YW9A 2BN7A 2EVCA 4KM3A 1R58A 2GG7A 5E5BA 1WLRA 1BOAA 3FMRA 5CDEA 2EVMA 4A6VA 2BHCA 3MATA 2V6CA 2ADUA 5CNXA 1N51A 4EGEA 1XGNA 1W2MA 4FLLA 4R60A 5JHUA 5FCHA 1B59A 2B3LA 1YW8A 4MATA 1QXYA 3BIPA 3CB6A 4S2RP 3PKBA 4U73A 1C24A 4IPAA 2BHAA 1W7VA 2GG9A 4FLIA 5JI6A 1KQ0A 4HXXA 4U75A 4U6EA 1R5HA
chains in the Genus database with same CATH topology
5CLSA 4IKTA 4ZWOA 4FLKA 2NQ7A 2B3HA 3RORA 2GU6A 2EA2A 1Y1NA 3MR1A 1WY2A 2P99A 3TB5A 2BWTA 4U71A 2NQ6A 5CIKA 1WBQA 2HOWA 1KQ9A 1XNZA 2BWWA 3PKCA 3IU9A 1QXWA 2Q93A 4ZWUA 3BIQA 3S6BA 1C27A 4FLJA 5CDLA 4IKRA 2P9AA 1CHMA 4FKCA 4ZWPA 2Q95A 2GG8A 4S01A 5CE6A 3FM3A 2EVOA 2MATA 2P98A 5FCFA 4OOKA 4IKUA 4RZYA 1B6AA 3L7GA 1XGMA 1PV9A 3FMQA 1KP0A 5D6EA 4FO8A 2GA2A 1R5GA 4IDYA 3CTZA 2BB7A 2GU5A 1C23A 5JFRA 3L24A 2GU7A 2GG0A 3IU8A 4U6CA 2BWYA 2B3KA 2Q8KA 4FO7A 4IKSA 4PNCA 2GG5A 1C21A 4B28A 2IW2A 1M35A 1QZYA 3PKEA 2GGCA 4IF7A 3RVAA 2G6PA 2BH3A 2V3YA 4S00A 4IU6A 4U6ZA 2GG3A 4U6WA 3CB5A 2GZ5A 2Q96A 1JAWA 2Q94A 2GGBA 2BWUA 1O0XA 4S2TP 1YVMA 2GG2A 2GU4A 3IG4A 3D27A 4U70A 1MATA 2BHDA 4JUQA 4RGZ1 2GTXA 1C22A 1WKMA 2OKNA 4PV4A 3BITA 2BWXA 1YW7A 2ZSGA 2V3ZA 3IU7A 2Q92A 3PKAA 1WL6A 4U1BA 1QXZA 2BWSA 4U6JA 2V3XA 2BWVA 4QR8A 2EA4A 1WN1A 2DFIA 3MX6A 4U69A 4U76A 4RZZA 5D6FA 4ZNGA 5CDVA 4IECA 1WL9A 1BN5A 2BHBA 1A16A 2OAZA 4A6WA 3TAVA 1XGOA 3Q6DA 4FUKA 1YJ3A 4Z7MA 1XGSA 3PKDA 1YW9A 2BN7A 2EVCA 4KM3A 1R58A 2GG7A 5E5BA 1WLRA 1BOAA 3FMRA 5CDEA 2EVMA 4A6VA 2BHCA 3MATA 2V6CA 2ADUA 5CNXA 1N51A 4EGEA 1XGNA 1W2MA 4FLLA 4R60A 5JHUA 5FCHA 1B59A 2B3LA 1YW8A 4MATA 1QXYA 3BIPA 3CB6A 4S2RP 3PKBA 4U73A 1C24A 4IPAA 2BHAA 1W7VA 2GG9A 4FLIA 5JI6A 1KQ0A 4HXXA 4U75A 4U6EA 1R5HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5CLS A;  4IKT A;  4ZWO A;  4FLK A;  2NQ7 A;  2B3H A;  3ROR A;  2GU6 A;  2EA2 A;  1Y1N A;  3MR1 A;  1WY2 A;  2P99 A;  3TB5 A;  2BWT A;  4U71 A;  2NQ6 A;  5CIK A;  1WBQ A;  2HOW A;  1KQ9 A;  1XNZ A;  2BWW A;  3PKC A;  3IU9 A;  1QXW A;  2Q93 A;  4ZWU A;  3BIQ A;  3S6B A;  1C27 A;  4FLJ A;  5CDL A;  4IKR A;  2P9A A;  1CHM A;  4FKC A;  4ZWP A;  2Q95 A;  2GG8 A;  4S01 A;  5CE6 A;  3FM3 A;  2EVO A;  2MAT A;  2P98 A;  5FCF A;  4OOK A;  4IKU A;  4RZY A;  1B6A A;  3L7G A;  1XGM A;  1PV9 A;  3FMQ A;  1KP0 A;  5D6E A;  4FO8 A;  2GA2 A;  1R5G A;  4IDY A;  3CTZ A;  2BB7 A;  2GU5 A;  1C23 A;  5JFR A;  3L24 A;  2GU7 A;  2GG0 A;  3IU8 A;  4U6C A;  2BWY A;  2B3K A;  2Q8K A;  4FO7 A;  4IKS A;  4PNC A;  2GG5 A;  1C21 A;  4B28 A;  2IW2 A;  1M35 A;  1QZY A;  3PKE A;  2GGC A;  4IF7 A;  3RVA A;  2G6P A;  2BH3 A;  2V3Y A;  4S00 A;  4IU6 A;  4U6Z A;  2GG3 A;  4U6W A;  3CB5 A;  2GZ5 A;  2Q96 A;  1JAW A;  2Q94 A;  2GGB A;  2BWU A;  1O0X A;  4S2T P;  1YVM A;  2GG2 A;  2GU4 A;  3IG4 A;  3D27 A;  4U70 A;  1MAT A;  2BHD A;  4JUQ A;  4RGZ 1;  2GTX A;  1C22 A;  1WKM A;  2OKN A;  4PV4 A;  3BIT A;  2BWX A;  1YW7 A;  2ZSG A;  2V3Z A;  3IU7 A;  2Q92 A;  3PKA A;  1WL6 A;  4U1B A;  1QXZ A;  2BWS A;  4U6J A;  2V3X A;  2BWV A;  4QR8 A;  2EA4 A;  1WN1 A;  2DFI A;  3MX6 A;  4U69 A;  4U76 A;  4RZZ A;  5D6F A;  4ZNG A;  5CDV A;  4IEC A;  1WL9 A;  1BN5 A;  2BHB A;  1A16 A;  2OAZ A;  4A6W A;  3TAV A;  1XGO A;  3Q6D A;  4FUK A;  1YJ3 A;  4Z7M A;  1XGS A;  3PKD A;  1YW9 A;  2BN7 A;  2EVC A;  4KM3 A;  1R58 A;  2GG7 A;  5E5B A;  1WLR A;  1BOA A;  3FMR A;  5CDE A;  2EVM A;  4A6V A;  2BHC A;  3MAT A;  2V6C A;  2ADU A;  5CNX A;  1N51 A;  4EGE A;  1XGN A;  1W2M A;  4FLL A;  4R60 A;  5JHU A;  5FCH A;  1B59 A;  2B3L A;  1YW8 A;  4MAT A;  1QXY A;  3BIP A;  3CB6 A;  4S2R P;  3PKB A;  4U73 A;  1C24 A;  4IPA A;  2BHA A;  1W7V A;  2GG9 A;  4FLI A;  5JI6 A;  1KQ0 A;  4HXX A;  4U75 A;  4U6E A;  1R5H A; 
#chains in the Genus database with same CATH topology
 5CLS A;  4IKT A;  4ZWO A;  4FLK A;  2NQ7 A;  2B3H A;  3ROR A;  2GU6 A;  2EA2 A;  1Y1N A;  3MR1 A;  1WY2 A;  2P99 A;  3TB5 A;  2BWT A;  4U71 A;  2NQ6 A;  5CIK A;  1WBQ A;  2HOW A;  1KQ9 A;  1XNZ A;  2BWW A;  3PKC A;  3IU9 A;  1QXW A;  2Q93 A;  4ZWU A;  3BIQ A;  3S6B A;  1C27 A;  4FLJ A;  5CDL A;  4IKR A;  2P9A A;  1CHM A;  4FKC A;  4ZWP A;  2Q95 A;  2GG8 A;  4S01 A;  5CE6 A;  3FM3 A;  2EVO A;  2MAT A;  2P98 A;  5FCF A;  4OOK A;  4IKU A;  4RZY A;  1B6A A;  3L7G A;  1XGM A;  1PV9 A;  3FMQ A;  1KP0 A;  5D6E A;  4FO8 A;  2GA2 A;  1R5G A;  4IDY A;  3CTZ A;  2BB7 A;  2GU5 A;  1C23 A;  5JFR A;  3L24 A;  2GU7 A;  2GG0 A;  3IU8 A;  4U6C A;  2BWY A;  2B3K A;  2Q8K A;  4FO7 A;  4IKS A;  4PNC A;  2GG5 A;  1C21 A;  4B28 A;  2IW2 A;  1M35 A;  1QZY A;  3PKE A;  2GGC A;  4IF7 A;  3RVA A;  2G6P A;  2BH3 A;  2V3Y A;  4S00 A;  4IU6 A;  4U6Z A;  2GG3 A;  4U6W A;  3CB5 A;  2GZ5 A;  2Q96 A;  1JAW A;  2Q94 A;  2GGB A;  2BWU A;  1O0X A;  4S2T P;  1YVM A;  2GG2 A;  2GU4 A;  3IG4 A;  3D27 A;  4U70 A;  1MAT A;  2BHD A;  4JUQ A;  4RGZ 1;  2GTX A;  1C22 A;  1WKM A;  2OKN A;  4PV4 A;  3BIT A;  2BWX A;  1YW7 A;  2ZSG A;  2V3Z A;  3IU7 A;  2Q92 A;  3PKA A;  1WL6 A;  4U1B A;  1QXZ A;  2BWS A;  4U6J A;  2V3X A;  2BWV A;  4QR8 A;  2EA4 A;  1WN1 A;  2DFI A;  3MX6 A;  4U69 A;  4U76 A;  4RZZ A;  5D6F A;  4ZNG A;  5CDV A;  4IEC A;  1WL9 A;  1BN5 A;  2BHB A;  1A16 A;  2OAZ A;  4A6W A;  3TAV A;  1XGO A;  3Q6D A;  4FUK A;  1YJ3 A;  4Z7M A;  1XGS A;  3PKD A;  1YW9 A;  2BN7 A;  2EVC A;  4KM3 A;  1R58 A;  2GG7 A;  5E5B A;  1WLR A;  1BOA A;  3FMR A;  5CDE A;  2EVM A;  4A6V A;  2BHC A;  3MAT A;  2V6C A;  2ADU A;  5CNX A;  1N51 A;  4EGE A;  1XGN A;  1W2M A;  4FLL A;  4R60 A;  5JHU A;  5FCH A;  1B59 A;  2B3L A;  1YW8 A;  4MAT A;  1QXY A;  3BIP A;  3CB6 A;  4S2R P;  3PKB A;  4U73 A;  1C24 A;  4IPA A;  2BHA A;  1W7V A;  2GG9 A;  4FLI A;  5JI6 A;  1KQ0 A;  4HXX A;  4U75 A;  4U6E A;  1R5H A; 
#chains in the Genus database with same CATH homology
 5CLS A;  4IKT A;  4ZWO A;  4FLK A;  2NQ7 A;  2B3H A;  3ROR A;  2GU6 A;  2EA2 A;  1Y1N A;  3MR1 A;  1WY2 A;  2P99 A;  3TB5 A;  2BWT A;  4U71 A;  2NQ6 A;  5CIK A;  1WBQ A;  2HOW A;  1KQ9 A;  1XNZ A;  2BWW A;  3PKC A;  3IU9 A;  1QXW A;  2Q93 A;  4ZWU A;  3BIQ A;  3S6B A;  1C27 A;  4FLJ A;  5CDL A;  4IKR A;  2P9A A;  1CHM A;  4FKC A;  4ZWP A;  2Q95 A;  2GG8 A;  4S01 A;  5CE6 A;  3FM3 A;  2EVO A;  2MAT A;  2P98 A;  5FCF A;  4OOK A;  4IKU A;  4RZY A;  1B6A A;  3L7G A;  1XGM A;  1PV9 A;  3FMQ A;  1KP0 A;  5D6E A;  4FO8 A;  2GA2 A;  1R5G A;  4IDY A;  3CTZ A;  2BB7 A;  2GU5 A;  1C23 A;  5JFR A;  3L24 A;  2GU7 A;  2GG0 A;  3IU8 A;  4U6C A;  2BWY A;  2B3K A;  2Q8K A;  4FO7 A;  4IKS A;  4PNC A;  2GG5 A;  1C21 A;  4B28 A;  2IW2 A;  1M35 A;  1QZY A;  3PKE A;  2GGC A;  4IF7 A;  3RVA A;  2G6P A;  2BH3 A;  2V3Y A;  4S00 A;  4IU6 A;  4U6Z A;  2GG3 A;  4U6W A;  3CB5 A;  2GZ5 A;  2Q96 A;  1JAW A;  2Q94 A;  2GGB A;  2BWU A;  1O0X A;  4S2T P;  1YVM A;  2GG2 A;  2GU4 A;  3IG4 A;  3D27 A;  4U70 A;  1MAT A;  2BHD A;  4JUQ A;  4RGZ 1;  2GTX A;  1C22 A;  1WKM A;  2OKN A;  4PV4 A;  3BIT A;  2BWX A;  1YW7 A;  2ZSG A;  2V3Z A;  3IU7 A;  2Q92 A;  3PKA A;  1WL6 A;  4U1B A;  1QXZ A;  2BWS A;  4U6J A;  2V3X A;  2BWV A;  4QR8 A;  2EA4 A;  1WN1 A;  2DFI A;  3MX6 A;  4U69 A;  4U76 A;  4RZZ A;  5D6F A;  4ZNG A;  5CDV A;  4IEC A;  1WL9 A;  1BN5 A;  2BHB A;  1A16 A;  2OAZ A;  4A6W A;  3TAV A;  1XGO A;  3Q6D A;  4FUK A;  1YJ3 A;  4Z7M A;  1XGS A;  3PKD A;  1YW9 A;  2BN7 A;  2EVC A;  4KM3 A;  1R58 A;  2GG7 A;  5E5B A;  1WLR A;  1BOA A;  3FMR A;  5CDE A;  2EVM A;  4A6V A;  2BHC A;  3MAT A;  2V6C A;  2ADU A;  5CNX A;  1N51 A;  4EGE A;  1XGN A;  1W2M A;  4FLL A;  4R60 A;  5JHU A;  5FCH A;  1B59 A;  2B3L A;  1YW8 A;  4MAT A;  1QXY A;  3BIP A;  3CB6 A;  4S2R P;  3PKB A;  4U73 A;  1C24 A;  4IPA A;  2BHA A;  1W7V A;  2GG9 A;  4FLI A;  5JI6 A;  1KQ0 A;  4HXX A;  4U75 A;  4U6E A;  1R5H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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