3PKBA

M. tuberculosis metap with bengamide analog y16, in mn form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidases by Bengamide Derivatives.
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase/hydrolase inhibitor
total genus 87
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2010-11-11

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3pkbA01
2B3HA 4RGZ1 2Q94A 4FKCA 2BHBA 5E5BA 2GG5A 1YW8A 4FO7A 4RZZA 4U70A 3CB5A 3FMQA 4S01A 1BOAA 1QZYA 2B3LA 4ZWUA 1BN5A 4U6CA 4U6ZA 5D6EA 3BITA 4IDYA 2IW2A 4A6WA 2BN7A 4U73A 3L24A 4IKRA 3PKDA 4FLJA 2BH3A 3Q6DA 3CTZA 2GG2A 5CE6A 5FCFA 3TAVA 4Z7MA 1O0XA 4IKTA 3IU8A 5CDEA 1WKMA 1WY2A 1YW9A 2OAZA 3MR1A 2EVOA 1QXWA 4U6WA 1C21A 1XGMA 4ZWOA 4U69A 2BWUA 5JI6A 2BWXA 2GU4A 1XGNA 4IU6A 3IG4A 1C22A 4U76A 2GG9A 2OKNA 1QXZA 1R58A 2V3XA 2NQ6A 2P99A 3RVAA 2BHAA 1C27A 5CDLA 2GG0A 1YVMA 2BWWA 2EA2A 1KQ9A 4PNCA 2GU5A 1XNZA 2GU6A 1A16A 1CHMA 4S2TP 4JUQA 4IKUA 2EVCA 5D6FA 4R60A 5JFRA 1W2MA 4HXXA 3TB5A 4B28A 3BIPA 3PKCA 2ADUA 2BWYA 2BWSA 5FCHA 4IKSA 2Q92A 3IU9A 1XGSA 4U75A 4FLLA 2GTXA 4OOKA 4ZNGA 4FLIA 1WBQA 2Q96A 1WL9A 4S00A 2BB7A 4S2RP 3FMRA 4ZWPA 3S6BA 4A6VA 2B3KA 2EVMA 2DFIA 1W7VA 2HOWA 1PV9A 5JHUA 2EA4A 2GZ5A 4U6JA 4EGEA 1C24A 4IPAA 4U6EA 2NQ7A 3MATA 1WLRA 1B59A 1N51A 3RORA 4MATA 1QXYA 4FUKA 4IF7A 4U1BA 2BWVA 3D27A 2V3ZA 1YW7A 2GGCA 4U71A 1WN1A 1R5HA 4FO8A 1Y1NA 3PKAA 3MX6A 4KM3A 1KQ0A 3FM3A 5CDVA 1B6AA 2GG3A 2BWTA 2GGBA 2P98A 2MATA 1C23A 2V3YA 3IU7A 1R5GA 2G6PA 5CLSA 2Q95A 2Q8KA 2BHDA 4PV4A 3CB6A 3L7GA 2GA2A 3BIQA 1YJ3A 4FLKA 4QR8A 1MATA 2BHCA 3PKEA 2ZSGA 4IECA 5CNXA 3PKBA 1M35A 1WL6A 2Q93A 1JAWA 2P9AA 2GG7A 2GG8A 5CIKA 2V6CA 1KP0A 2GU7A 1XGOA 4RZYA
chains in the Genus database with same CATH superfamily
2B3HA 4RGZ1 2Q94A 4FKCA 2BHBA 5E5BA 2GG5A 1YW8A 4FO7A 4RZZA 4U70A 3CB5A 3FMQA 4S01A 1BOAA 1QZYA 2B3LA 4ZWUA 1BN5A 4U6CA 4U6ZA 5D6EA 3BITA 4IDYA 2IW2A 4A6WA 2BN7A 4U73A 3L24A 4IKRA 3PKDA 4FLJA 2BH3A 3Q6DA 3CTZA 2GG2A 5CE6A 5FCFA 3TAVA 4Z7MA 1O0XA 4IKTA 3IU8A 5CDEA 1WKMA 1WY2A 1YW9A 2OAZA 3MR1A 2EVOA 1QXWA 4U6WA 1C21A 1XGMA 4ZWOA 4U69A 2BWUA 5JI6A 2BWXA 2GU4A 1XGNA 4IU6A 3IG4A 1C22A 4U76A 2GG9A 2OKNA 1QXZA 1R58A 2V3XA 2NQ6A 2P99A 3RVAA 2BHAA 1C27A 5CDLA 2GG0A 1YVMA 2BWWA 2EA2A 1KQ9A 4PNCA 2GU5A 1XNZA 2GU6A 1A16A 1CHMA 4S2TP 4JUQA 4IKUA 2EVCA 5D6FA 4R60A 5JFRA 1W2MA 4HXXA 3TB5A 4B28A 3BIPA 3PKCA 2ADUA 2BWYA 2BWSA 5FCHA 4IKSA 2Q92A 3IU9A 1XGSA 4U75A 4FLLA 2GTXA 4OOKA 4ZNGA 4FLIA 1WBQA 2Q96A 1WL9A 4S00A 2BB7A 4S2RP 3FMRA 4ZWPA 3S6BA 4A6VA 2B3KA 2EVMA 2DFIA 1W7VA 2HOWA 1PV9A 5JHUA 2EA4A 2GZ5A 4U6JA 4EGEA 1C24A 4IPAA 4U6EA 2NQ7A 3MATA 1WLRA 1B59A 1N51A 3RORA 4MATA 1QXYA 4FUKA 4IF7A 4U1BA 2BWVA 3D27A 2V3ZA 1YW7A 2GGCA 4U71A 1WN1A 1R5HA 4FO8A 1Y1NA 3PKAA 3MX6A 4KM3A 1KQ0A 3FM3A 5CDVA 1B6AA 2GG3A 2BWTA 2GGBA 2P98A 2MATA 1C23A 2V3YA 3IU7A 1R5GA 2G6PA 5CLSA 2Q95A 2Q8KA 2BHDA 4PV4A 3CB6A 3L7GA 2GA2A 3BIQA 1YJ3A 4FLKA 4QR8A 1MATA 2BHCA 3PKEA 2ZSGA 4IECA 5CNXA 3PKBA 1M35A 1WL6A 2Q93A 1JAWA 2P9AA 2GG7A 2GG8A 5CIKA 2V6CA 1KP0A 2GU7A 1XGOA 4RZYA
chains in the Genus database with same CATH topology
2B3HA 4RGZ1 2Q94A 4FKCA 2BHBA 5E5BA 2GG5A 1YW8A 4FO7A 4RZZA 4U70A 3CB5A 3FMQA 4S01A 1BOAA 1QZYA 2B3LA 4ZWUA 1BN5A 4U6CA 4U6ZA 5D6EA 3BITA 4IDYA 2IW2A 4A6WA 2BN7A 4U73A 3L24A 4IKRA 3PKDA 4FLJA 2BH3A 3Q6DA 3CTZA 2GG2A 5CE6A 5FCFA 3TAVA 4Z7MA 1O0XA 4IKTA 3IU8A 5CDEA 1WKMA 1WY2A 1YW9A 2OAZA 3MR1A 2EVOA 1QXWA 4U6WA 1C21A 1XGMA 4ZWOA 4U69A 2BWUA 5JI6A 2BWXA 2GU4A 1XGNA 4IU6A 3IG4A 1C22A 4U76A 2GG9A 2OKNA 1QXZA 1R58A 2V3XA 2NQ6A 2P99A 3RVAA 2BHAA 1C27A 5CDLA 2GG0A 1YVMA 2BWWA 2EA2A 1KQ9A 4PNCA 2GU5A 1XNZA 2GU6A 1A16A 1CHMA 4S2TP 4JUQA 4IKUA 2EVCA 5D6FA 4R60A 5JFRA 1W2MA 4HXXA 3TB5A 4B28A 3BIPA 3PKCA 2ADUA 2BWYA 2BWSA 5FCHA 4IKSA 2Q92A 3IU9A 1XGSA 4U75A 4FLLA 2GTXA 4OOKA 4ZNGA 4FLIA 1WBQA 2Q96A 1WL9A 4S00A 2BB7A 4S2RP 3FMRA 4ZWPA 3S6BA 4A6VA 2B3KA 2EVMA 2DFIA 1W7VA 2HOWA 1PV9A 5JHUA 2EA4A 2GZ5A 4U6JA 4EGEA 1C24A 4IPAA 4U6EA 2NQ7A 3MATA 1WLRA 1B59A 1N51A 3RORA 4MATA 1QXYA 4FUKA 4IF7A 4U1BA 2BWVA 3D27A 2V3ZA 1YW7A 2GGCA 4U71A 1WN1A 1R5HA 4FO8A 1Y1NA 3PKAA 3MX6A 4KM3A 1KQ0A 3FM3A 5CDVA 1B6AA 2GG3A 2BWTA 2GGBA 2P98A 2MATA 1C23A 2V3YA 3IU7A 1R5GA 2G6PA 5CLSA 2Q95A 2Q8KA 2BHDA 4PV4A 3CB6A 3L7GA 2GA2A 3BIQA 1YJ3A 4FLKA 4QR8A 1MATA 2BHCA 3PKEA 2ZSGA 4IECA 5CNXA 3PKBA 1M35A 1WL6A 2Q93A 1JAWA 2P9AA 2GG7A 2GG8A 5CIKA 2V6CA 1KP0A 2GU7A 1XGOA 4RZYA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 2B3H A;  4RGZ 1;  2Q94 A;  4FKC A;  2BHB A;  5E5B A;  2GG5 A;  1YW8 A;  4FO7 A;  4RZZ A;  4U70 A;  3CB5 A;  3FMQ A;  4S01 A;  1BOA A;  1QZY A;  2B3L A;  4ZWU A;  1BN5 A;  4U6C A;  4U6Z A;  5D6E A;  3BIT A;  4IDY A;  2IW2 A;  4A6W A;  2BN7 A;  4U73 A;  3L24 A;  4IKR A;  3PKD A;  4FLJ A;  2BH3 A;  3Q6D A;  3CTZ A;  2GG2 A;  5CE6 A;  5FCF A;  3TAV A;  4Z7M A;  1O0X A;  4IKT A;  3IU8 A;  5CDE A;  1WKM A;  1WY2 A;  1YW9 A;  2OAZ A;  3MR1 A;  2EVO A;  1QXW A;  4U6W A;  1C21 A;  1XGM A;  4ZWO A;  4U69 A;  2BWU A;  5JI6 A;  2BWX A;  2GU4 A;  1XGN A;  4IU6 A;  3IG4 A;  1C22 A;  4U76 A;  2GG9 A;  2OKN A;  1QXZ A;  1R58 A;  2V3X A;  2NQ6 A;  2P99 A;  3RVA A;  2BHA A;  1C27 A;  5CDL A;  2GG0 A;  1YVM A;  2BWW A;  2EA2 A;  1KQ9 A;  4PNC A;  2GU5 A;  1XNZ A;  2GU6 A;  1A16 A;  1CHM A;  4S2T P;  4JUQ A;  4IKU A;  2EVC A;  5D6F A;  4R60 A;  5JFR A;  1W2M A;  4HXX A;  3TB5 A;  4B28 A;  3BIP A;  3PKC A;  2ADU A;  2BWY A;  2BWS A;  5FCH A;  4IKS A;  2Q92 A;  3IU9 A;  1XGS A;  4U75 A;  4FLL A;  2GTX A;  4OOK A;  4ZNG A;  4FLI A;  1WBQ A;  2Q96 A;  1WL9 A;  4S00 A;  2BB7 A;  4S2R P;  3FMR A;  4ZWP A;  3S6B A;  4A6V A;  2B3K A;  2EVM A;  2DFI A;  1W7V A;  2HOW A;  1PV9 A;  5JHU A;  2EA4 A;  2GZ5 A;  4U6J A;  4EGE A;  1C24 A;  4IPA A;  4U6E A;  2NQ7 A;  3MAT A;  1WLR A;  1B59 A;  1N51 A;  3ROR A;  4MAT A;  1QXY A;  4FUK A;  4IF7 A;  4U1B A;  2BWV A;  3D27 A;  2V3Z A;  1YW7 A;  2GGC A;  4U71 A;  1WN1 A;  1R5H A;  4FO8 A;  1Y1N A;  3PKA A;  3MX6 A;  4KM3 A;  1KQ0 A;  3FM3 A;  5CDV A;  1B6A A;  2GG3 A;  2BWT A;  2GGB A;  2P98 A;  2MAT A;  1C23 A;  2V3Y A;  3IU7 A;  1R5G A;  2G6P A;  5CLS A;  2Q95 A;  2Q8K A;  2BHD A;  4PV4 A;  3CB6 A;  3L7G A;  2GA2 A;  3BIQ A;  1YJ3 A;  4FLK A;  4QR8 A;  1MAT A;  2BHC A;  3PKE A;  2ZSG A;  4IEC A;  5CNX A;  3PKB A;  1M35 A;  1WL6 A;  2Q93 A;  1JAW A;  2P9A A;  2GG7 A;  2GG8 A;  5CIK A;  2V6C A;  1KP0 A;  2GU7 A;  1XGO A;  4RZY A; 
#chains in the Genus database with same CATH topology
 2B3H A;  4RGZ 1;  2Q94 A;  4FKC A;  2BHB A;  5E5B A;  2GG5 A;  1YW8 A;  4FO7 A;  4RZZ A;  4U70 A;  3CB5 A;  3FMQ A;  4S01 A;  1BOA A;  1QZY A;  2B3L A;  4ZWU A;  1BN5 A;  4U6C A;  4U6Z A;  5D6E A;  3BIT A;  4IDY A;  2IW2 A;  4A6W A;  2BN7 A;  4U73 A;  3L24 A;  4IKR A;  3PKD A;  4FLJ A;  2BH3 A;  3Q6D A;  3CTZ A;  2GG2 A;  5CE6 A;  5FCF A;  3TAV A;  4Z7M A;  1O0X A;  4IKT A;  3IU8 A;  5CDE A;  1WKM A;  1WY2 A;  1YW9 A;  2OAZ A;  3MR1 A;  2EVO A;  1QXW A;  4U6W A;  1C21 A;  1XGM A;  4ZWO A;  4U69 A;  2BWU A;  5JI6 A;  2BWX A;  2GU4 A;  1XGN A;  4IU6 A;  3IG4 A;  1C22 A;  4U76 A;  2GG9 A;  2OKN A;  1QXZ A;  1R58 A;  2V3X A;  2NQ6 A;  2P99 A;  3RVA A;  2BHA A;  1C27 A;  5CDL A;  2GG0 A;  1YVM A;  2BWW A;  2EA2 A;  1KQ9 A;  4PNC A;  2GU5 A;  1XNZ A;  2GU6 A;  1A16 A;  1CHM A;  4S2T P;  4JUQ A;  4IKU A;  2EVC A;  5D6F A;  4R60 A;  5JFR A;  1W2M A;  4HXX A;  3TB5 A;  4B28 A;  3BIP A;  3PKC A;  2ADU A;  2BWY A;  2BWS A;  5FCH A;  4IKS A;  2Q92 A;  3IU9 A;  1XGS A;  4U75 A;  4FLL A;  2GTX A;  4OOK A;  4ZNG A;  4FLI A;  1WBQ A;  2Q96 A;  1WL9 A;  4S00 A;  2BB7 A;  4S2R P;  3FMR A;  4ZWP A;  3S6B A;  4A6V A;  2B3K A;  2EVM A;  2DFI A;  1W7V A;  2HOW A;  1PV9 A;  5JHU A;  2EA4 A;  2GZ5 A;  4U6J A;  4EGE A;  1C24 A;  4IPA A;  4U6E A;  2NQ7 A;  3MAT A;  1WLR A;  1B59 A;  1N51 A;  3ROR A;  4MAT A;  1QXY A;  4FUK A;  4IF7 A;  4U1B A;  2BWV A;  3D27 A;  2V3Z A;  1YW7 A;  2GGC A;  4U71 A;  1WN1 A;  1R5H A;  4FO8 A;  1Y1N A;  3PKA A;  3MX6 A;  4KM3 A;  1KQ0 A;  3FM3 A;  5CDV A;  1B6A A;  2GG3 A;  2BWT A;  2GGB A;  2P98 A;  2MAT A;  1C23 A;  2V3Y A;  3IU7 A;  1R5G A;  2G6P A;  5CLS A;  2Q95 A;  2Q8K A;  2BHD A;  4PV4 A;  3CB6 A;  3L7G A;  2GA2 A;  3BIQ A;  1YJ3 A;  4FLK A;  4QR8 A;  1MAT A;  2BHC A;  3PKE A;  2ZSG A;  4IEC A;  5CNX A;  3PKB A;  1M35 A;  1WL6 A;  2Q93 A;  1JAW A;  2P9A A;  2GG7 A;  2GG8 A;  5CIK A;  2V6C A;  1KP0 A;  2GU7 A;  1XGO A;  4RZY A; 
#chains in the Genus database with same CATH homology
 2B3H A;  4RGZ 1;  2Q94 A;  4FKC A;  2BHB A;  5E5B A;  2GG5 A;  1YW8 A;  4FO7 A;  4RZZ A;  4U70 A;  3CB5 A;  3FMQ A;  4S01 A;  1BOA A;  1QZY A;  2B3L A;  4ZWU A;  1BN5 A;  4U6C A;  4U6Z A;  5D6E A;  3BIT A;  4IDY A;  2IW2 A;  4A6W A;  2BN7 A;  4U73 A;  3L24 A;  4IKR A;  3PKD A;  4FLJ A;  2BH3 A;  3Q6D A;  3CTZ A;  2GG2 A;  5CE6 A;  5FCF A;  3TAV A;  4Z7M A;  1O0X A;  4IKT A;  3IU8 A;  5CDE A;  1WKM A;  1WY2 A;  1YW9 A;  2OAZ A;  3MR1 A;  2EVO A;  1QXW A;  4U6W A;  1C21 A;  1XGM A;  4ZWO A;  4U69 A;  2BWU A;  5JI6 A;  2BWX A;  2GU4 A;  1XGN A;  4IU6 A;  3IG4 A;  1C22 A;  4U76 A;  2GG9 A;  2OKN A;  1QXZ A;  1R58 A;  2V3X A;  2NQ6 A;  2P99 A;  3RVA A;  2BHA A;  1C27 A;  5CDL A;  2GG0 A;  1YVM A;  2BWW A;  2EA2 A;  1KQ9 A;  4PNC A;  2GU5 A;  1XNZ A;  2GU6 A;  1A16 A;  1CHM A;  4S2T P;  4JUQ A;  4IKU A;  2EVC A;  5D6F A;  4R60 A;  5JFR A;  1W2M A;  4HXX A;  3TB5 A;  4B28 A;  3BIP A;  3PKC A;  2ADU A;  2BWY A;  2BWS A;  5FCH A;  4IKS A;  2Q92 A;  3IU9 A;  1XGS A;  4U75 A;  4FLL A;  2GTX A;  4OOK A;  4ZNG A;  4FLI A;  1WBQ A;  2Q96 A;  1WL9 A;  4S00 A;  2BB7 A;  4S2R P;  3FMR A;  4ZWP A;  3S6B A;  4A6V A;  2B3K A;  2EVM A;  2DFI A;  1W7V A;  2HOW A;  1PV9 A;  5JHU A;  2EA4 A;  2GZ5 A;  4U6J A;  4EGE A;  1C24 A;  4IPA A;  4U6E A;  2NQ7 A;  3MAT A;  1WLR A;  1B59 A;  1N51 A;  3ROR A;  4MAT A;  1QXY A;  4FUK A;  4IF7 A;  4U1B A;  2BWV A;  3D27 A;  2V3Z A;  1YW7 A;  2GGC A;  4U71 A;  1WN1 A;  1R5H A;  4FO8 A;  1Y1N A;  3PKA A;  3MX6 A;  4KM3 A;  1KQ0 A;  3FM3 A;  5CDV A;  1B6A A;  2GG3 A;  2BWT A;  2GGB A;  2P98 A;  2MAT A;  1C23 A;  2V3Y A;  3IU7 A;  1R5G A;  2G6P A;  5CLS A;  2Q95 A;  2Q8K A;  2BHD A;  4PV4 A;  3CB6 A;  3L7G A;  2GA2 A;  3BIQ A;  1YJ3 A;  4FLK A;  4QR8 A;  1MAT A;  2BHC A;  3PKE A;  2ZSG A;  4IEC A;  5CNX A;  3PKB A;  1M35 A;  1WL6 A;  2Q93 A;  1JAW A;  2P9A A;  2GG7 A;  2GG8 A;  5CIK A;  2V6C A;  1KP0 A;  2GU7 A;  1XGO A;  4RZY A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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