3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
b'PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
5D6FA 1WN1A 2GU4A 5CIKA 5E5BA 4U75A 2GG9A 4HXXA 1WKMA 2Q95A 4IKSA 2Q92A 2GGBA 4OOKA 4U6WA 2GG0A 1R58A 2B3HA 4FLLA 4IKUA 1QXWA 3TB5A 2ADUA 3L24A 3TAVA 2BH3A 2MATA 4PV4A 4U71A 4U6EA 5CNXA 1KP0A 1CHMA 4RZZA 1BOAA 5CDEA 1C23A 4ZWPA 4U6ZA 2GU5A 1W2MA 1N51A 1C21A 4ZNGA 5JI6A 2BN7A 1O0XA 1XGMA 2GG2A 2BWVA 4B28A 3BIPA 1YW8A 2NQ6A 3RORA 1R5GA 3S6BA 1XGSA 4U6JA 4IKRA 4RGZ1 3BITA 3IU7A 1W7VA 2V3ZA 4EGEA 3BIQA 1XGNA 3FMRA 4MATA 1M35A 2BHBA 3MR1A 4S2TP 5CE6A 2BWWA 3PKEA 5CDLA 2BWSA 2GG7A 2Q94A 4S00A 2GG8A 3CTZA 3FMQA 2Q96A 3IG4A 2V3XA 3PKBA 4IDYA 5FCFA 5CDVA 2EVOA 4FKCA 3Q6DA 4FLKA 2NQ7A 4IKTA 2EA4A 1WL6A 4JUQA 4QR8A 1A16A 3IU9A 4IECA 4U6CA 2G6PA 3MATA 4ZWUA 1JAWA 1XGOA 1WBQA 4FLJA 3RVAA 5FCHA 1YW9A 4U73A 1WY2A 3D27A 4S2RP 2GG5A 5D6EA 1B6AA 1YJ3A 3CB6A 2BWTA 3MX6A 4A6VA 1BN5A 2GTXA 1QXZA 4S01A 1C22A 5CLSA 2P99A 2Q8KA 4A6WA 2B3KA 1YVMA 2EA2A 4IPAA 2BHDA 4RZYA 4FLIA 3CB5A 2GU7A 1C27A 4IU6A 1YW7A 2GZ5A 5JFRA 1PV9A 3L7GA 2P9AA 2BWXA 4Z7MA 2BHAA 2OKNA 4FO7A 1XNZA 1B59A 1R5HA 2EVMA 4FO8A 2BWYA 2GU6A 1KQ9A 3PKAA 4U69A 1C24A 2HOWA 2BHCA 2B3LA 4IF7A 2GGCA 5JHUA 4U70A 2ZSGA 2V3YA 1QXYA 2V6CA 1WLRA 2DFIA 2GG3A 1QZYA 3FM3A 2P98A 2Q93A 1KQ0A 1MATA 2IW2A 3IU8A 4KM3A 1WL9A 3PKDA 4FUKA 2OAZA 2BWUA 1Y1NA 4U1BA 4ZWOA 2EVCA 4R60A 2BB7A 3PKCA 4PNCA 4U76A 2GA2A
chains in the Genus database with same CATH superfamily
5D6FA 1WN1A 2GU4A 5CIKA 5E5BA 4U75A 2GG9A 4HXXA 1WKMA 2Q95A 4IKSA 2Q92A 2GGBA 4OOKA 4U6WA 2GG0A 1R58A 2B3HA 4FLLA 4IKUA 1QXWA 3TB5A 2ADUA 3L24A 3TAVA 2BH3A 2MATA 4PV4A 4U71A 4U6EA 5CNXA 1KP0A 1CHMA 4RZZA 1BOAA 5CDEA 1C23A 4ZWPA 4U6ZA 2GU5A 1W2MA 1N51A 1C21A 4ZNGA 5JI6A 2BN7A 1O0XA 1XGMA 2GG2A 2BWVA 4B28A 3BIPA 1YW8A 2NQ6A 3RORA 1R5GA 3S6BA 1XGSA 4U6JA 4IKRA 4RGZ1 3BITA 3IU7A 1W7VA 2V3ZA 4EGEA 3BIQA 1XGNA 3FMRA 4MATA 1M35A 2BHBA 3MR1A 4S2TP 5CE6A 2BWWA 3PKEA 5CDLA 2BWSA 2GG7A 2Q94A 4S00A 2GG8A 3CTZA 3FMQA 2Q96A 3IG4A 2V3XA 3PKBA 4IDYA 5FCFA 5CDVA 2EVOA 4FKCA 3Q6DA 4FLKA 2NQ7A 4IKTA 2EA4A 1WL6A 4JUQA 4QR8A 1A16A 3IU9A 4IECA 4U6CA 2G6PA 3MATA 4ZWUA 1JAWA 1XGOA 1WBQA 4FLJA 3RVAA 5FCHA 1YW9A 4U73A 1WY2A 3D27A 4S2RP 2GG5A 5D6EA 1B6AA 1YJ3A 3CB6A 2BWTA 3MX6A 4A6VA 1BN5A 2GTXA 1QXZA 4S01A 1C22A 5CLSA 2P99A 2Q8KA 4A6WA 2B3KA 1YVMA 2EA2A 4IPAA 2BHDA 4RZYA 4FLIA 3CB5A 2GU7A 1C27A 4IU6A 1YW7A 2GZ5A 5JFRA 1PV9A 3L7GA 2P9AA 2BWXA 4Z7MA 2BHAA 2OKNA 4FO7A 1XNZA 1B59A 1R5HA 2EVMA 4FO8A 2BWYA 2GU6A 1KQ9A 3PKAA 4U69A 1C24A 2HOWA 2BHCA 2B3LA 4IF7A 2GGCA 5JHUA 4U70A 2ZSGA 2V3YA 1QXYA 2V6CA 1WLRA 2DFIA 2GG3A 1QZYA 3FM3A 2P98A 2Q93A 1KQ0A 1MATA 2IW2A 3IU8A 4KM3A 1WL9A 3PKDA 4FUKA 2OAZA 2BWUA 1Y1NA 4U1BA 4ZWOA 2EVCA 4R60A 2BB7A 3PKCA 4PNCA 4U76A 2GA2A
chains in the Genus database with same CATH topology
5D6FA 1WN1A 2GU4A 5CIKA 5E5BA 4U75A 2GG9A 4HXXA 1WKMA 2Q95A 4IKSA 2Q92A 2GGBA 4OOKA 4U6WA 2GG0A 1R58A 2B3HA 4FLLA 4IKUA 1QXWA 3TB5A 2ADUA 3L24A 3TAVA 2BH3A 2MATA 4PV4A 4U71A 4U6EA 5CNXA 1KP0A 1CHMA 4RZZA 1BOAA 5CDEA 1C23A 4ZWPA 4U6ZA 2GU5A 1W2MA 1N51A 1C21A 4ZNGA 5JI6A 2BN7A 1O0XA 1XGMA 2GG2A 2BWVA 4B28A 3BIPA 1YW8A 2NQ6A 3RORA 1R5GA 3S6BA 1XGSA 4U6JA 4IKRA 4RGZ1 3BITA 3IU7A 1W7VA 2V3ZA 4EGEA 3BIQA 1XGNA 3FMRA 4MATA 1M35A 2BHBA 3MR1A 4S2TP 5CE6A 2BWWA 3PKEA 5CDLA 2BWSA 2GG7A 2Q94A 4S00A 2GG8A 3CTZA 3FMQA 2Q96A 3IG4A 2V3XA 3PKBA 4IDYA 5FCFA 5CDVA 2EVOA 4FKCA 3Q6DA 4FLKA 2NQ7A 4IKTA 2EA4A 1WL6A 4JUQA 4QR8A 1A16A 3IU9A 4IECA 4U6CA 2G6PA 3MATA 4ZWUA 1JAWA 1XGOA 1WBQA 4FLJA 3RVAA 5FCHA 1YW9A 4U73A 1WY2A 3D27A 4S2RP 2GG5A 5D6EA 1B6AA 1YJ3A 3CB6A 2BWTA 3MX6A 4A6VA 1BN5A 2GTXA 1QXZA 4S01A 1C22A 5CLSA 2P99A 2Q8KA 4A6WA 2B3KA 1YVMA 2EA2A 4IPAA 2BHDA 4RZYA 4FLIA 3CB5A 2GU7A 1C27A 4IU6A 1YW7A 2GZ5A 5JFRA 1PV9A 3L7GA 2P9AA 2BWXA 4Z7MA 2BHAA 2OKNA 4FO7A 1XNZA 1B59A 1R5HA 2EVMA 4FO8A 2BWYA 2GU6A 1KQ9A 3PKAA 4U69A 1C24A 2HOWA 2BHCA 2B3LA 4IF7A 2GGCA 5JHUA 4U70A 2ZSGA 2V3YA 1QXYA 2V6CA 1WLRA 2DFIA 2GG3A 1QZYA 3FM3A 2P98A 2Q93A 1KQ0A 1MATA 2IW2A 3IU8A 4KM3A 1WL9A 3PKDA 4FUKA 2OAZA 2BWUA 1Y1NA 4U1BA 4ZWOA 2EVCA 4R60A 2BB7A 3PKCA 4PNCA 4U76A 2GA2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5D6F A;  1WN1 A;  2GU4 A;  5CIK A;  5E5B A;  4U75 A;  2GG9 A;  4HXX A;  1WKM A;  2Q95 A;  4IKS A;  2Q92 A;  2GGB A;  4OOK A;  4U6W A;  2GG0 A;  1R58 A;  2B3H A;  4FLL A;  4IKU A;  1QXW A;  3TB5 A;  2ADU A;  3L24 A;  3TAV A;  2BH3 A;  2MAT A;  4PV4 A;  4U71 A;  4U6E A;  5CNX A;  1KP0 A;  1CHM A;  4RZZ A;  1BOA A;  5CDE A;  1C23 A;  4ZWP A;  4U6Z A;  2GU5 A;  1W2M A;  1N51 A;  1C21 A;  4ZNG A;  5JI6 A;  2BN7 A;  1O0X A;  1XGM A;  2GG2 A;  2BWV A;  4B28 A;  3BIP A;  1YW8 A;  2NQ6 A;  3ROR A;  1R5G A;  3S6B A;  1XGS A;  4U6J A;  4IKR A;  4RGZ 1;  3BIT A;  3IU7 A;  1W7V A;  2V3Z A;  4EGE A;  3BIQ A;  1XGN A;  3FMR A;  4MAT A;  1M35 A;  2BHB A;  3MR1 A;  4S2T P;  5CE6 A;  2BWW A;  3PKE A;  5CDL A;  2BWS A;  2GG7 A;  2Q94 A;  4S00 A;  2GG8 A;  3CTZ A;  3FMQ A;  2Q96 A;  3IG4 A;  2V3X A;  3PKB A;  4IDY A;  5FCF A;  5CDV A;  2EVO A;  4FKC A;  3Q6D A;  4FLK A;  2NQ7 A;  4IKT A;  2EA4 A;  1WL6 A;  4JUQ A;  4QR8 A;  1A16 A;  3IU9 A;  4IEC A;  4U6C A;  2G6P A;  3MAT A;  4ZWU A;  1JAW A;  1XGO A;  1WBQ A;  4FLJ A;  3RVA A;  5FCH A;  1YW9 A;  4U73 A;  1WY2 A;  3D27 A;  4S2R P;  2GG5 A;  5D6E A;  1B6A A;  1YJ3 A;  3CB6 A;  2BWT A;  3MX6 A;  4A6V A;  1BN5 A;  2GTX A;  1QXZ A;  4S01 A;  1C22 A;  5CLS A;  2P99 A;  2Q8K A;  4A6W A;  2B3K A;  1YVM A;  2EA2 A;  4IPA A;  2BHD A;  4RZY A;  4FLI A;  3CB5 A;  2GU7 A;  1C27 A;  4IU6 A;  1YW7 A;  2GZ5 A;  5JFR A;  1PV9 A;  3L7G A;  2P9A A;  2BWX A;  4Z7M A;  2BHA A;  2OKN A;  4FO7 A;  1XNZ A;  1B59 A;  1R5H A;  2EVM A;  4FO8 A;  2BWY A;  2GU6 A;  1KQ9 A;  3PKA A;  4U69 A;  1C24 A;  2HOW A;  2BHC A;  2B3L A;  4IF7 A;  2GGC A;  5JHU A;  4U70 A;  2ZSG A;  2V3Y A;  1QXY A;  2V6C A;  1WLR A;  2DFI A;  2GG3 A;  1QZY A;  3FM3 A;  2P98 A;  2Q93 A;  1KQ0 A;  1MAT A;  2IW2 A;  3IU8 A;  4KM3 A;  1WL9 A;  3PKD A;  4FUK A;  2OAZ A;  2BWU A;  1Y1N A;  4U1B A;  4ZWO A;  2EVC A;  4R60 A;  2BB7 A;  3PKC A;  4PNC A;  4U76 A;  2GA2 A; 
#chains in the Genus database with same CATH topology
 5D6F A;  1WN1 A;  2GU4 A;  5CIK A;  5E5B A;  4U75 A;  2GG9 A;  4HXX A;  1WKM A;  2Q95 A;  4IKS A;  2Q92 A;  2GGB A;  4OOK A;  4U6W A;  2GG0 A;  1R58 A;  2B3H A;  4FLL A;  4IKU A;  1QXW A;  3TB5 A;  2ADU A;  3L24 A;  3TAV A;  2BH3 A;  2MAT A;  4PV4 A;  4U71 A;  4U6E A;  5CNX A;  1KP0 A;  1CHM A;  4RZZ A;  1BOA A;  5CDE A;  1C23 A;  4ZWP A;  4U6Z A;  2GU5 A;  1W2M A;  1N51 A;  1C21 A;  4ZNG A;  5JI6 A;  2BN7 A;  1O0X A;  1XGM A;  2GG2 A;  2BWV A;  4B28 A;  3BIP A;  1YW8 A;  2NQ6 A;  3ROR A;  1R5G A;  3S6B A;  1XGS A;  4U6J A;  4IKR A;  4RGZ 1;  3BIT A;  3IU7 A;  1W7V A;  2V3Z A;  4EGE A;  3BIQ A;  1XGN A;  3FMR A;  4MAT A;  1M35 A;  2BHB A;  3MR1 A;  4S2T P;  5CE6 A;  2BWW A;  3PKE A;  5CDL A;  2BWS A;  2GG7 A;  2Q94 A;  4S00 A;  2GG8 A;  3CTZ A;  3FMQ A;  2Q96 A;  3IG4 A;  2V3X A;  3PKB A;  4IDY A;  5FCF A;  5CDV A;  2EVO A;  4FKC A;  3Q6D A;  4FLK A;  2NQ7 A;  4IKT A;  2EA4 A;  1WL6 A;  4JUQ A;  4QR8 A;  1A16 A;  3IU9 A;  4IEC A;  4U6C A;  2G6P A;  3MAT A;  4ZWU A;  1JAW A;  1XGO A;  1WBQ A;  4FLJ A;  3RVA A;  5FCH A;  1YW9 A;  4U73 A;  1WY2 A;  3D27 A;  4S2R P;  2GG5 A;  5D6E A;  1B6A A;  1YJ3 A;  3CB6 A;  2BWT A;  3MX6 A;  4A6V A;  1BN5 A;  2GTX A;  1QXZ A;  4S01 A;  1C22 A;  5CLS A;  2P99 A;  2Q8K A;  4A6W A;  2B3K A;  1YVM A;  2EA2 A;  4IPA A;  2BHD A;  4RZY A;  4FLI A;  3CB5 A;  2GU7 A;  1C27 A;  4IU6 A;  1YW7 A;  2GZ5 A;  5JFR A;  1PV9 A;  3L7G A;  2P9A A;  2BWX A;  4Z7M A;  2BHA A;  2OKN A;  4FO7 A;  1XNZ A;  1B59 A;  1R5H A;  2EVM A;  4FO8 A;  2BWY A;  2GU6 A;  1KQ9 A;  3PKA A;  4U69 A;  1C24 A;  2HOW A;  2BHC A;  2B3L A;  4IF7 A;  2GGC A;  5JHU A;  4U70 A;  2ZSG A;  2V3Y A;  1QXY A;  2V6C A;  1WLR A;  2DFI A;  2GG3 A;  1QZY A;  3FM3 A;  2P98 A;  2Q93 A;  1KQ0 A;  1MAT A;  2IW2 A;  3IU8 A;  4KM3 A;  1WL9 A;  3PKD A;  4FUK A;  2OAZ A;  2BWU A;  1Y1N A;  4U1B A;  4ZWO A;  2EVC A;  4R60 A;  2BB7 A;  3PKC A;  4PNC A;  4U76 A;  2GA2 A; 
#chains in the Genus database with same CATH homology
 5D6F A;  1WN1 A;  2GU4 A;  5CIK A;  5E5B A;  4U75 A;  2GG9 A;  4HXX A;  1WKM A;  2Q95 A;  4IKS A;  2Q92 A;  2GGB A;  4OOK A;  4U6W A;  2GG0 A;  1R58 A;  2B3H A;  4FLL A;  4IKU A;  1QXW A;  3TB5 A;  2ADU A;  3L24 A;  3TAV A;  2BH3 A;  2MAT A;  4PV4 A;  4U71 A;  4U6E A;  5CNX A;  1KP0 A;  1CHM A;  4RZZ A;  1BOA A;  5CDE A;  1C23 A;  4ZWP A;  4U6Z A;  2GU5 A;  1W2M A;  1N51 A;  1C21 A;  4ZNG A;  5JI6 A;  2BN7 A;  1O0X A;  1XGM A;  2GG2 A;  2BWV A;  4B28 A;  3BIP A;  1YW8 A;  2NQ6 A;  3ROR A;  1R5G A;  3S6B A;  1XGS A;  4U6J A;  4IKR A;  4RGZ 1;  3BIT A;  3IU7 A;  1W7V A;  2V3Z A;  4EGE A;  3BIQ A;  1XGN A;  3FMR A;  4MAT A;  1M35 A;  2BHB A;  3MR1 A;  4S2T P;  5CE6 A;  2BWW A;  3PKE A;  5CDL A;  2BWS A;  2GG7 A;  2Q94 A;  4S00 A;  2GG8 A;  3CTZ A;  3FMQ A;  2Q96 A;  3IG4 A;  2V3X A;  3PKB A;  4IDY A;  5FCF A;  5CDV A;  2EVO A;  4FKC A;  3Q6D A;  4FLK A;  2NQ7 A;  4IKT A;  2EA4 A;  1WL6 A;  4JUQ A;  4QR8 A;  1A16 A;  3IU9 A;  4IEC A;  4U6C A;  2G6P A;  3MAT A;  4ZWU A;  1JAW A;  1XGO A;  1WBQ A;  4FLJ A;  3RVA A;  5FCH A;  1YW9 A;  4U73 A;  1WY2 A;  3D27 A;  4S2R P;  2GG5 A;  5D6E A;  1B6A A;  1YJ3 A;  3CB6 A;  2BWT A;  3MX6 A;  4A6V A;  1BN5 A;  2GTX A;  1QXZ A;  4S01 A;  1C22 A;  5CLS A;  2P99 A;  2Q8K A;  4A6W A;  2B3K A;  1YVM A;  2EA2 A;  4IPA A;  2BHD A;  4RZY A;  4FLI A;  3CB5 A;  2GU7 A;  1C27 A;  4IU6 A;  1YW7 A;  2GZ5 A;  5JFR A;  1PV9 A;  3L7G A;  2P9A A;  2BWX A;  4Z7M A;  2BHA A;  2OKN A;  4FO7 A;  1XNZ A;  1B59 A;  1R5H A;  2EVM A;  4FO8 A;  2BWY A;  2GU6 A;  1KQ9 A;  3PKA A;  4U69 A;  1C24 A;  2HOW A;  2BHC A;  2B3L A;  4IF7 A;  2GGC A;  5JHU A;  4U70 A;  2ZSG A;  2V3Y A;  1QXY A;  2V6C A;  1WLR A;  2DFI A;  2GG3 A;  1QZY A;  3FM3 A;  2P98 A;  2Q93 A;  1KQ0 A;  1MAT A;  2IW2 A;  3IU8 A;  4KM3 A;  1WL9 A;  3PKD A;  4FUK A;  2OAZ A;  2BWU A;  1Y1N A;  4U1B A;  4ZWO A;  2EVC A;  4R60 A;  2BB7 A;  3PKC A;  4PNC A;  4U76 A;  2GA2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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