3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
1QXYA 3MATA 4U6CA 2EA4A 1B59A 1CHMA 1QXWA 2GG3A 2EVCA 3CB5A 3FMQA 1C22A 1C27A 1KQ9A 3IG4A 2P9AA 3CB6A 3MR1A 2GG0A 3BIQA 2GGCA 4S01A 1WKMA 1YJ3A 4IECA 5CDVA 3L7GA 2GG2A 4U73A 5CDLA 1WY2A 4U75A 1YVMA 1WBQA 2NQ6A 3TAVA 5D6FA 2BHCA 2BWWA 2GG8A 4S2RP 4IKSA 3BITA 5FCHA 4OOKA 3BIPA 2BN7A 2GU6A 2DFIA 2BWXA 1O0XA 4PNCA 1R58A 5CIKA 4U76A 3PKDA 1M35A 4U6ZA 4ZNGA 3FM3A 1C24A 4U70A 3RVAA 1W2MA 2GZ5A 5CDEA 3S6BA 2BWTA 2GG9A 3PKAA 4FUKA 4RGZ1 3TB5A 5JHUA 2GGBA 1A16A 2GU5A 4HXXA 2BHBA 2V3ZA 4FLJA 2Q8KA 1Y1NA 2BH3A 1C21A 3CTZA 5CLSA 2V6CA 4S2TP 1QXZA 4ZWUA 5CNXA 4KM3A 4R60A 3L24A 1PV9A 1XGSA 2BWYA 4B28A 1XGNA 2BWVA 4IPAA 1BOAA 2OKNA 3FMRA 1R5GA 2G6PA 2GG5A 2GG7A 1R5HA 2GU4A 2V3XA 2Q96A 2EVOA 2GU7A 1MATA 2B3KA 4FLIA 4Z7MA 2B3LA 1YW7A 2EA2A 5CE6A 2V3YA 2P99A 5FCFA 4U6JA 2Q93A 4RZZA 1QZYA 4IF7A 1JAWA 4IDYA 4U69A 3RORA 3IU9A 1C23A 1XGOA 2OAZA 4FKCA 4QR8A 3Q6DA 2ZSGA 1B6AA 1WL9A 2BWUA 4IU6A 4A6VA 2NQ7A 1N51A 4ZWPA 2Q95A 3PKCA 3MX6A 2EVMA 4U6WA 4S00A 1XGMA 4FO8A 1YW9A 2IW2A 1KP0A 2GTXA 2Q92A 3IU8A 1XNZA 4U71A 5E5BA 4FLLA 1WN1A 1KQ0A 4JUQA 2HOWA 2MATA 2ADUA 3PKBA 2P98A 4FLKA 2BHAA 2B3HA 2BB7A 4IKUA 1BN5A 5JI6A 3PKEA 1WLRA 1W7VA 4MATA 4PV4A 4EGEA 4FO7A 4ZWOA 4U1BA 4IKRA 2GA2A 1WL6A 2Q94A 2BHDA 4RZYA 4U6EA 5D6EA 1YW8A 4A6WA 3IU7A 4IKTA 5JFRA 3D27A 2BWSA
chains in the Genus database with same CATH superfamily
1QXYA 3MATA 4U6CA 2EA4A 1B59A 1CHMA 1QXWA 2GG3A 2EVCA 3CB5A 3FMQA 1C22A 1C27A 1KQ9A 3IG4A 2P9AA 3CB6A 3MR1A 2GG0A 3BIQA 2GGCA 4S01A 1WKMA 1YJ3A 4IECA 5CDVA 3L7GA 2GG2A 4U73A 5CDLA 1WY2A 4U75A 1YVMA 1WBQA 2NQ6A 3TAVA 5D6FA 2BHCA 2BWWA 2GG8A 4S2RP 4IKSA 3BITA 5FCHA 4OOKA 3BIPA 2BN7A 2GU6A 2DFIA 2BWXA 1O0XA 4PNCA 1R58A 5CIKA 4U76A 3PKDA 1M35A 4U6ZA 4ZNGA 3FM3A 1C24A 4U70A 3RVAA 1W2MA 2GZ5A 5CDEA 3S6BA 2BWTA 2GG9A 3PKAA 4FUKA 4RGZ1 3TB5A 5JHUA 2GGBA 1A16A 2GU5A 4HXXA 2BHBA 2V3ZA 4FLJA 2Q8KA 1Y1NA 2BH3A 1C21A 3CTZA 5CLSA 2V6CA 4S2TP 1QXZA 4ZWUA 5CNXA 4KM3A 4R60A 3L24A 1PV9A 1XGSA 2BWYA 4B28A 1XGNA 2BWVA 4IPAA 1BOAA 2OKNA 3FMRA 1R5GA 2G6PA 2GG5A 2GG7A 1R5HA 2GU4A 2V3XA 2Q96A 2EVOA 2GU7A 1MATA 2B3KA 4FLIA 4Z7MA 2B3LA 1YW7A 2EA2A 5CE6A 2V3YA 2P99A 5FCFA 4U6JA 2Q93A 4RZZA 1QZYA 4IF7A 1JAWA 4IDYA 4U69A 3RORA 3IU9A 1C23A 1XGOA 2OAZA 4FKCA 4QR8A 3Q6DA 2ZSGA 1B6AA 1WL9A 2BWUA 4IU6A 4A6VA 2NQ7A 1N51A 4ZWPA 2Q95A 3PKCA 3MX6A 2EVMA 4U6WA 4S00A 1XGMA 4FO8A 1YW9A 2IW2A 1KP0A 2GTXA 2Q92A 3IU8A 1XNZA 4U71A 5E5BA 4FLLA 1WN1A 1KQ0A 4JUQA 2HOWA 2MATA 2ADUA 3PKBA 2P98A 4FLKA 2BHAA 2B3HA 2BB7A 4IKUA 1BN5A 5JI6A 3PKEA 1WLRA 1W7VA 4MATA 4PV4A 4EGEA 4FO7A 4ZWOA 4U1BA 4IKRA 2GA2A 1WL6A 2Q94A 2BHDA 4RZYA 4U6EA 5D6EA 1YW8A 4A6WA 3IU7A 4IKTA 5JFRA 3D27A 2BWSA
chains in the Genus database with same CATH topology
1QXYA 3MATA 4U6CA 2EA4A 1B59A 1CHMA 1QXWA 2GG3A 2EVCA 3CB5A 3FMQA 1C22A 1C27A 1KQ9A 3IG4A 2P9AA 3CB6A 3MR1A 2GG0A 3BIQA 2GGCA 4S01A 1WKMA 1YJ3A 4IECA 5CDVA 3L7GA 2GG2A 4U73A 5CDLA 1WY2A 4U75A 1YVMA 1WBQA 2NQ6A 3TAVA 5D6FA 2BHCA 2BWWA 2GG8A 4S2RP 4IKSA 3BITA 5FCHA 4OOKA 3BIPA 2BN7A 2GU6A 2DFIA 2BWXA 1O0XA 4PNCA 1R58A 5CIKA 4U76A 3PKDA 1M35A 4U6ZA 4ZNGA 3FM3A 1C24A 4U70A 3RVAA 1W2MA 2GZ5A 5CDEA 3S6BA 2BWTA 2GG9A 3PKAA 4FUKA 4RGZ1 3TB5A 5JHUA 2GGBA 1A16A 2GU5A 4HXXA 2BHBA 2V3ZA 4FLJA 2Q8KA 1Y1NA 2BH3A 1C21A 3CTZA 5CLSA 2V6CA 4S2TP 1QXZA 4ZWUA 5CNXA 4KM3A 4R60A 3L24A 1PV9A 1XGSA 2BWYA 4B28A 1XGNA 2BWVA 4IPAA 1BOAA 2OKNA 3FMRA 1R5GA 2G6PA 2GG5A 2GG7A 1R5HA 2GU4A 2V3XA 2Q96A 2EVOA 2GU7A 1MATA 2B3KA 4FLIA 4Z7MA 2B3LA 1YW7A 2EA2A 5CE6A 2V3YA 2P99A 5FCFA 4U6JA 2Q93A 4RZZA 1QZYA 4IF7A 1JAWA 4IDYA 4U69A 3RORA 3IU9A 1C23A 1XGOA 2OAZA 4FKCA 4QR8A 3Q6DA 2ZSGA 1B6AA 1WL9A 2BWUA 4IU6A 4A6VA 2NQ7A 1N51A 4ZWPA 2Q95A 3PKCA 3MX6A 2EVMA 4U6WA 4S00A 1XGMA 4FO8A 1YW9A 2IW2A 1KP0A 2GTXA 2Q92A 3IU8A 1XNZA 4U71A 5E5BA 4FLLA 1WN1A 1KQ0A 4JUQA 2HOWA 2MATA 2ADUA 3PKBA 2P98A 4FLKA 2BHAA 2B3HA 2BB7A 4IKUA 1BN5A 5JI6A 3PKEA 1WLRA 1W7VA 4MATA 4PV4A 4EGEA 4FO7A 4ZWOA 4U1BA 4IKRA 2GA2A 1WL6A 2Q94A 2BHDA 4RZYA 4U6EA 5D6EA 1YW8A 4A6WA 3IU7A 4IKTA 5JFRA 3D27A 2BWSA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1QXY A;  3MAT A;  4U6C A;  2EA4 A;  1B59 A;  1CHM A;  1QXW A;  2GG3 A;  2EVC A;  3CB5 A;  3FMQ A;  1C22 A;  1C27 A;  1KQ9 A;  3IG4 A;  2P9A A;  3CB6 A;  3MR1 A;  2GG0 A;  3BIQ A;  2GGC A;  4S01 A;  1WKM A;  1YJ3 A;  4IEC A;  5CDV A;  3L7G A;  2GG2 A;  4U73 A;  5CDL A;  1WY2 A;  4U75 A;  1YVM A;  1WBQ A;  2NQ6 A;  3TAV A;  5D6F A;  2BHC A;  2BWW A;  2GG8 A;  4S2R P;  4IKS A;  3BIT A;  5FCH A;  4OOK A;  3BIP A;  2BN7 A;  2GU6 A;  2DFI A;  2BWX A;  1O0X A;  4PNC A;  1R58 A;  5CIK A;  4U76 A;  3PKD A;  1M35 A;  4U6Z A;  4ZNG A;  3FM3 A;  1C24 A;  4U70 A;  3RVA A;  1W2M A;  2GZ5 A;  5CDE A;  3S6B A;  2BWT A;  2GG9 A;  3PKA A;  4FUK A;  4RGZ 1;  3TB5 A;  5JHU A;  2GGB A;  1A16 A;  2GU5 A;  4HXX A;  2BHB A;  2V3Z A;  4FLJ A;  2Q8K A;  1Y1N A;  2BH3 A;  1C21 A;  3CTZ A;  5CLS A;  2V6C A;  4S2T P;  1QXZ A;  4ZWU A;  5CNX A;  4KM3 A;  4R60 A;  3L24 A;  1PV9 A;  1XGS A;  2BWY A;  4B28 A;  1XGN A;  2BWV A;  4IPA A;  1BOA A;  2OKN A;  3FMR A;  1R5G A;  2G6P A;  2GG5 A;  2GG7 A;  1R5H A;  2GU4 A;  2V3X A;  2Q96 A;  2EVO A;  2GU7 A;  1MAT A;  2B3K A;  4FLI A;  4Z7M A;  2B3L A;  1YW7 A;  2EA2 A;  5CE6 A;  2V3Y A;  2P99 A;  5FCF A;  4U6J A;  2Q93 A;  4RZZ A;  1QZY A;  4IF7 A;  1JAW A;  4IDY A;  4U69 A;  3ROR A;  3IU9 A;  1C23 A;  1XGO A;  2OAZ A;  4FKC A;  4QR8 A;  3Q6D A;  2ZSG A;  1B6A A;  1WL9 A;  2BWU A;  4IU6 A;  4A6V A;  2NQ7 A;  1N51 A;  4ZWP A;  2Q95 A;  3PKC A;  3MX6 A;  2EVM A;  4U6W A;  4S00 A;  1XGM A;  4FO8 A;  1YW9 A;  2IW2 A;  1KP0 A;  2GTX A;  2Q92 A;  3IU8 A;  1XNZ A;  4U71 A;  5E5B A;  4FLL A;  1WN1 A;  1KQ0 A;  4JUQ A;  2HOW A;  2MAT A;  2ADU A;  3PKB A;  2P98 A;  4FLK A;  2BHA A;  2B3H A;  2BB7 A;  4IKU A;  1BN5 A;  5JI6 A;  3PKE A;  1WLR A;  1W7V A;  4MAT A;  4PV4 A;  4EGE A;  4FO7 A;  4ZWO A;  4U1B A;  4IKR A;  2GA2 A;  1WL6 A;  2Q94 A;  2BHD A;  4RZY A;  4U6E A;  5D6E A;  1YW8 A;  4A6W A;  3IU7 A;  4IKT A;  5JFR A;  3D27 A;  2BWS A; 
#chains in the Genus database with same CATH topology
 1QXY A;  3MAT A;  4U6C A;  2EA4 A;  1B59 A;  1CHM A;  1QXW A;  2GG3 A;  2EVC A;  3CB5 A;  3FMQ A;  1C22 A;  1C27 A;  1KQ9 A;  3IG4 A;  2P9A A;  3CB6 A;  3MR1 A;  2GG0 A;  3BIQ A;  2GGC A;  4S01 A;  1WKM A;  1YJ3 A;  4IEC A;  5CDV A;  3L7G A;  2GG2 A;  4U73 A;  5CDL A;  1WY2 A;  4U75 A;  1YVM A;  1WBQ A;  2NQ6 A;  3TAV A;  5D6F A;  2BHC A;  2BWW A;  2GG8 A;  4S2R P;  4IKS A;  3BIT A;  5FCH A;  4OOK A;  3BIP A;  2BN7 A;  2GU6 A;  2DFI A;  2BWX A;  1O0X A;  4PNC A;  1R58 A;  5CIK A;  4U76 A;  3PKD A;  1M35 A;  4U6Z A;  4ZNG A;  3FM3 A;  1C24 A;  4U70 A;  3RVA A;  1W2M A;  2GZ5 A;  5CDE A;  3S6B A;  2BWT A;  2GG9 A;  3PKA A;  4FUK A;  4RGZ 1;  3TB5 A;  5JHU A;  2GGB A;  1A16 A;  2GU5 A;  4HXX A;  2BHB A;  2V3Z A;  4FLJ A;  2Q8K A;  1Y1N A;  2BH3 A;  1C21 A;  3CTZ A;  5CLS A;  2V6C A;  4S2T P;  1QXZ A;  4ZWU A;  5CNX A;  4KM3 A;  4R60 A;  3L24 A;  1PV9 A;  1XGS A;  2BWY A;  4B28 A;  1XGN A;  2BWV A;  4IPA A;  1BOA A;  2OKN A;  3FMR A;  1R5G A;  2G6P A;  2GG5 A;  2GG7 A;  1R5H A;  2GU4 A;  2V3X A;  2Q96 A;  2EVO A;  2GU7 A;  1MAT A;  2B3K A;  4FLI A;  4Z7M A;  2B3L A;  1YW7 A;  2EA2 A;  5CE6 A;  2V3Y A;  2P99 A;  5FCF A;  4U6J A;  2Q93 A;  4RZZ A;  1QZY A;  4IF7 A;  1JAW A;  4IDY A;  4U69 A;  3ROR A;  3IU9 A;  1C23 A;  1XGO A;  2OAZ A;  4FKC A;  4QR8 A;  3Q6D A;  2ZSG A;  1B6A A;  1WL9 A;  2BWU A;  4IU6 A;  4A6V A;  2NQ7 A;  1N51 A;  4ZWP A;  2Q95 A;  3PKC A;  3MX6 A;  2EVM A;  4U6W A;  4S00 A;  1XGM A;  4FO8 A;  1YW9 A;  2IW2 A;  1KP0 A;  2GTX A;  2Q92 A;  3IU8 A;  1XNZ A;  4U71 A;  5E5B A;  4FLL A;  1WN1 A;  1KQ0 A;  4JUQ A;  2HOW A;  2MAT A;  2ADU A;  3PKB A;  2P98 A;  4FLK A;  2BHA A;  2B3H A;  2BB7 A;  4IKU A;  1BN5 A;  5JI6 A;  3PKE A;  1WLR A;  1W7V A;  4MAT A;  4PV4 A;  4EGE A;  4FO7 A;  4ZWO A;  4U1B A;  4IKR A;  2GA2 A;  1WL6 A;  2Q94 A;  2BHD A;  4RZY A;  4U6E A;  5D6E A;  1YW8 A;  4A6W A;  3IU7 A;  4IKT A;  5JFR A;  3D27 A;  2BWS A; 
#chains in the Genus database with same CATH homology
 1QXY A;  3MAT A;  4U6C A;  2EA4 A;  1B59 A;  1CHM A;  1QXW A;  2GG3 A;  2EVC A;  3CB5 A;  3FMQ A;  1C22 A;  1C27 A;  1KQ9 A;  3IG4 A;  2P9A A;  3CB6 A;  3MR1 A;  2GG0 A;  3BIQ A;  2GGC A;  4S01 A;  1WKM A;  1YJ3 A;  4IEC A;  5CDV A;  3L7G A;  2GG2 A;  4U73 A;  5CDL A;  1WY2 A;  4U75 A;  1YVM A;  1WBQ A;  2NQ6 A;  3TAV A;  5D6F A;  2BHC A;  2BWW A;  2GG8 A;  4S2R P;  4IKS A;  3BIT A;  5FCH A;  4OOK A;  3BIP A;  2BN7 A;  2GU6 A;  2DFI A;  2BWX A;  1O0X A;  4PNC A;  1R58 A;  5CIK A;  4U76 A;  3PKD A;  1M35 A;  4U6Z A;  4ZNG A;  3FM3 A;  1C24 A;  4U70 A;  3RVA A;  1W2M A;  2GZ5 A;  5CDE A;  3S6B A;  2BWT A;  2GG9 A;  3PKA A;  4FUK A;  4RGZ 1;  3TB5 A;  5JHU A;  2GGB A;  1A16 A;  2GU5 A;  4HXX A;  2BHB A;  2V3Z A;  4FLJ A;  2Q8K A;  1Y1N A;  2BH3 A;  1C21 A;  3CTZ A;  5CLS A;  2V6C A;  4S2T P;  1QXZ A;  4ZWU A;  5CNX A;  4KM3 A;  4R60 A;  3L24 A;  1PV9 A;  1XGS A;  2BWY A;  4B28 A;  1XGN A;  2BWV A;  4IPA A;  1BOA A;  2OKN A;  3FMR A;  1R5G A;  2G6P A;  2GG5 A;  2GG7 A;  1R5H A;  2GU4 A;  2V3X A;  2Q96 A;  2EVO A;  2GU7 A;  1MAT A;  2B3K A;  4FLI A;  4Z7M A;  2B3L A;  1YW7 A;  2EA2 A;  5CE6 A;  2V3Y A;  2P99 A;  5FCF A;  4U6J A;  2Q93 A;  4RZZ A;  1QZY A;  4IF7 A;  1JAW A;  4IDY A;  4U69 A;  3ROR A;  3IU9 A;  1C23 A;  1XGO A;  2OAZ A;  4FKC A;  4QR8 A;  3Q6D A;  2ZSG A;  1B6A A;  1WL9 A;  2BWU A;  4IU6 A;  4A6V A;  2NQ7 A;  1N51 A;  4ZWP A;  2Q95 A;  3PKC A;  3MX6 A;  2EVM A;  4U6W A;  4S00 A;  1XGM A;  4FO8 A;  1YW9 A;  2IW2 A;  1KP0 A;  2GTX A;  2Q92 A;  3IU8 A;  1XNZ A;  4U71 A;  5E5B A;  4FLL A;  1WN1 A;  1KQ0 A;  4JUQ A;  2HOW A;  2MAT A;  2ADU A;  3PKB A;  2P98 A;  4FLK A;  2BHA A;  2B3H A;  2BB7 A;  4IKU A;  1BN5 A;  5JI6 A;  3PKE A;  1WLR A;  1W7V A;  4MAT A;  4PV4 A;  4EGE A;  4FO7 A;  4ZWO A;  4U1B A;  4IKR A;  2GA2 A;  1WL6 A;  2Q94 A;  2BHD A;  4RZY A;  4U6E A;  5D6E A;  1YW8 A;  4A6W A;  3IU7 A;  4IKT A;  5JFR A;  3D27 A;  2BWS A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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