3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
1C22A 2P9AA 2Q94A 3IU8A 2BN7A 2BWVA 2Q95A 3MR1A 5CDEA 1O0XA 2GA2A 4FKCA 3Q6DA 2BWUA 2P98A 2V3XA 2EVOA 5CDVA 4HXXA 2BWYA 2GG5A 4IF7A 1WL9A 2EVMA 4ZNGA 3TAVA 4U6ZA 4U6JA 4U71A 4RZYA 4U6CA 4IKSA 4PV4A 2GU7A 2IW2A 2Q92A 2V3ZA 2GGBA 3TB5A 1QXWA 5CNXA 3PKEA 2BWTA 5D6EA 5FCHA 5CLSA 2BWWA 2GG9A 4KM3A 4OOKA 2GTXA 4U1BA 1XGSA 2B3LA 1WN1A 2GG2A 5CIKA 3IU9A 1YVMA 1N51A 1QXZA 1R5HA 1C27A 1KQ9A 4RZZA 3L7GA 3RVAA 4QR8A 1KP0A 2DFIA 4ZWPA 2ADUA 2BHCA 4A6WA 2GU6A 4U6WA 4IDYA 2GG7A 4FO8A 2BWXA 1A16A 1XGMA 3FM3A 2V6CA 2GGCA 4FLIA 2EVCA 4FUKA 3L24A 2P99A 4IKRA 1WBQA 2EA4A 4PNCA 4A6VA 3IG4A 5FCFA 2BHAA 4R60A 2ZSGA 1XGNA 1JAWA 3CB5A 5CDLA 5JHUA 2G6PA 1XGOA 3CTZA 1B59A 1C23A 1R5GA 2B3KA 4S2RP 3S6BA 4U76A 1W7VA 2GZ5A 1XNZA 2NQ7A 3CB6A 2Q8KA 1WLRA 4FLLA 1R58A 4U70A 5JI6A 1YW8A 2BB7A 2OKNA 5JFRA 4FO7A 2NQ6A 1YJ3A 3PKDA 1C24A 2GU4A 3IU7A 4S2TP 2HOWA 1B6AA 1BOAA 2BHBA 4IECA 4S01A 1C21A 1WKMA 4IKUA 5CE6A 3BIPA 5E5BA 3RORA 4ZWUA 4MATA 1MATA 1BN5A 2GG3A 1Y1NA 2Q93A 3FMQA 1QXYA 2EA2A 2GG0A 4S00A 1WY2A 1PV9A 3MATA 1YW7A 3PKCA 1M35A 1WL6A 4IPAA 4U69A 3MX6A 4FLJA 4JUQA 4EGEA 4Z7MA 2Q96A 2GU5A 3BIQA 4U73A 1QZYA 1W2MA 4RGZ1 1CHMA 4IKTA 2B3HA 2BHDA 2BWSA 1KQ0A 2V3YA 4ZWOA 3BITA 3FMRA 2GG8A 2MATA 4FLKA 2BH3A 5D6FA 4B28A 3PKBA 2OAZA 4U6EA 4IU6A 1YW9A 3PKAA 4U75A 3D27A
chains in the Genus database with same CATH superfamily
1C22A 2P9AA 2Q94A 3IU8A 2BN7A 2BWVA 2Q95A 3MR1A 5CDEA 1O0XA 2GA2A 4FKCA 3Q6DA 2BWUA 2P98A 2V3XA 2EVOA 5CDVA 4HXXA 2BWYA 2GG5A 4IF7A 1WL9A 2EVMA 4ZNGA 3TAVA 4U6ZA 4U6JA 4U71A 4RZYA 4U6CA 4IKSA 4PV4A 2GU7A 2IW2A 2Q92A 2V3ZA 2GGBA 3TB5A 1QXWA 5CNXA 3PKEA 2BWTA 5D6EA 5FCHA 5CLSA 2BWWA 2GG9A 4KM3A 4OOKA 2GTXA 4U1BA 1XGSA 2B3LA 1WN1A 2GG2A 5CIKA 3IU9A 1YVMA 1N51A 1QXZA 1R5HA 1C27A 1KQ9A 4RZZA 3L7GA 3RVAA 4QR8A 1KP0A 2DFIA 4ZWPA 2ADUA 2BHCA 4A6WA 2GU6A 4U6WA 4IDYA 2GG7A 4FO8A 2BWXA 1A16A 1XGMA 3FM3A 2V6CA 2GGCA 4FLIA 2EVCA 4FUKA 3L24A 2P99A 4IKRA 1WBQA 2EA4A 4PNCA 4A6VA 3IG4A 5FCFA 2BHAA 4R60A 2ZSGA 1XGNA 1JAWA 3CB5A 5CDLA 5JHUA 2G6PA 1XGOA 3CTZA 1B59A 1C23A 1R5GA 2B3KA 4S2RP 3S6BA 4U76A 1W7VA 2GZ5A 1XNZA 2NQ7A 3CB6A 2Q8KA 1WLRA 4FLLA 1R58A 4U70A 5JI6A 1YW8A 2BB7A 2OKNA 5JFRA 4FO7A 2NQ6A 1YJ3A 3PKDA 1C24A 2GU4A 3IU7A 4S2TP 2HOWA 1B6AA 1BOAA 2BHBA 4IECA 4S01A 1C21A 1WKMA 4IKUA 5CE6A 3BIPA 5E5BA 3RORA 4ZWUA 4MATA 1MATA 1BN5A 2GG3A 1Y1NA 2Q93A 3FMQA 1QXYA 2EA2A 2GG0A 4S00A 1WY2A 1PV9A 3MATA 1YW7A 3PKCA 1M35A 1WL6A 4IPAA 4U69A 3MX6A 4FLJA 4JUQA 4EGEA 4Z7MA 2Q96A 2GU5A 3BIQA 4U73A 1QZYA 1W2MA 4RGZ1 1CHMA 4IKTA 2B3HA 2BHDA 2BWSA 1KQ0A 2V3YA 4ZWOA 3BITA 3FMRA 2GG8A 2MATA 4FLKA 2BH3A 5D6FA 4B28A 3PKBA 2OAZA 4U6EA 4IU6A 1YW9A 3PKAA 4U75A 3D27A
chains in the Genus database with same CATH topology
1C22A 2P9AA 2Q94A 3IU8A 2BN7A 2BWVA 2Q95A 3MR1A 5CDEA 1O0XA 2GA2A 4FKCA 3Q6DA 2BWUA 2P98A 2V3XA 2EVOA 5CDVA 4HXXA 2BWYA 2GG5A 4IF7A 1WL9A 2EVMA 4ZNGA 3TAVA 4U6ZA 4U6JA 4U71A 4RZYA 4U6CA 4IKSA 4PV4A 2GU7A 2IW2A 2Q92A 2V3ZA 2GGBA 3TB5A 1QXWA 5CNXA 3PKEA 2BWTA 5D6EA 5FCHA 5CLSA 2BWWA 2GG9A 4KM3A 4OOKA 2GTXA 4U1BA 1XGSA 2B3LA 1WN1A 2GG2A 5CIKA 3IU9A 1YVMA 1N51A 1QXZA 1R5HA 1C27A 1KQ9A 4RZZA 3L7GA 3RVAA 4QR8A 1KP0A 2DFIA 4ZWPA 2ADUA 2BHCA 4A6WA 2GU6A 4U6WA 4IDYA 2GG7A 4FO8A 2BWXA 1A16A 1XGMA 3FM3A 2V6CA 2GGCA 4FLIA 2EVCA 4FUKA 3L24A 2P99A 4IKRA 1WBQA 2EA4A 4PNCA 4A6VA 3IG4A 5FCFA 2BHAA 4R60A 2ZSGA 1XGNA 1JAWA 3CB5A 5CDLA 5JHUA 2G6PA 1XGOA 3CTZA 1B59A 1C23A 1R5GA 2B3KA 4S2RP 3S6BA 4U76A 1W7VA 2GZ5A 1XNZA 2NQ7A 3CB6A 2Q8KA 1WLRA 4FLLA 1R58A 4U70A 5JI6A 1YW8A 2BB7A 2OKNA 5JFRA 4FO7A 2NQ6A 1YJ3A 3PKDA 1C24A 2GU4A 3IU7A 4S2TP 2HOWA 1B6AA 1BOAA 2BHBA 4IECA 4S01A 1C21A 1WKMA 4IKUA 5CE6A 3BIPA 5E5BA 3RORA 4ZWUA 4MATA 1MATA 1BN5A 2GG3A 1Y1NA 2Q93A 3FMQA 1QXYA 2EA2A 2GG0A 4S00A 1WY2A 1PV9A 3MATA 1YW7A 3PKCA 1M35A 1WL6A 4IPAA 4U69A 3MX6A 4FLJA 4JUQA 4EGEA 4Z7MA 2Q96A 2GU5A 3BIQA 4U73A 1QZYA 1W2MA 4RGZ1 1CHMA 4IKTA 2B3HA 2BHDA 2BWSA 1KQ0A 2V3YA 4ZWOA 3BITA 3FMRA 2GG8A 2MATA 4FLKA 2BH3A 5D6FA 4B28A 3PKBA 2OAZA 4U6EA 4IU6A 1YW9A 3PKAA 4U75A 3D27A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1C22 A;  2P9A A;  2Q94 A;  3IU8 A;  2BN7 A;  2BWV A;  2Q95 A;  3MR1 A;  5CDE A;  1O0X A;  2GA2 A;  4FKC A;  3Q6D A;  2BWU A;  2P98 A;  2V3X A;  2EVO A;  5CDV A;  4HXX A;  2BWY A;  2GG5 A;  4IF7 A;  1WL9 A;  2EVM A;  4ZNG A;  3TAV A;  4U6Z A;  4U6J A;  4U71 A;  4RZY A;  4U6C A;  4IKS A;  4PV4 A;  2GU7 A;  2IW2 A;  2Q92 A;  2V3Z A;  2GGB A;  3TB5 A;  1QXW A;  5CNX A;  3PKE A;  2BWT A;  5D6E A;  5FCH A;  5CLS A;  2BWW A;  2GG9 A;  4KM3 A;  4OOK A;  2GTX A;  4U1B A;  1XGS A;  2B3L A;  1WN1 A;  2GG2 A;  5CIK A;  3IU9 A;  1YVM A;  1N51 A;  1QXZ A;  1R5H A;  1C27 A;  1KQ9 A;  4RZZ A;  3L7G A;  3RVA A;  4QR8 A;  1KP0 A;  2DFI A;  4ZWP A;  2ADU A;  2BHC A;  4A6W A;  2GU6 A;  4U6W A;  4IDY A;  2GG7 A;  4FO8 A;  2BWX A;  1A16 A;  1XGM A;  3FM3 A;  2V6C A;  2GGC A;  4FLI A;  2EVC A;  4FUK A;  3L24 A;  2P99 A;  4IKR A;  1WBQ A;  2EA4 A;  4PNC A;  4A6V A;  3IG4 A;  5FCF A;  2BHA A;  4R60 A;  2ZSG A;  1XGN A;  1JAW A;  3CB5 A;  5CDL A;  5JHU A;  2G6P A;  1XGO A;  3CTZ A;  1B59 A;  1C23 A;  1R5G A;  2B3K A;  4S2R P;  3S6B A;  4U76 A;  1W7V A;  2GZ5 A;  1XNZ A;  2NQ7 A;  3CB6 A;  2Q8K A;  1WLR A;  4FLL A;  1R58 A;  4U70 A;  5JI6 A;  1YW8 A;  2BB7 A;  2OKN A;  5JFR A;  4FO7 A;  2NQ6 A;  1YJ3 A;  3PKD A;  1C24 A;  2GU4 A;  3IU7 A;  4S2T P;  2HOW A;  1B6A A;  1BOA A;  2BHB A;  4IEC A;  4S01 A;  1C21 A;  1WKM A;  4IKU A;  5CE6 A;  3BIP A;  5E5B A;  3ROR A;  4ZWU A;  4MAT A;  1MAT A;  1BN5 A;  2GG3 A;  1Y1N A;  2Q93 A;  3FMQ A;  1QXY A;  2EA2 A;  2GG0 A;  4S00 A;  1WY2 A;  1PV9 A;  3MAT A;  1YW7 A;  3PKC A;  1M35 A;  1WL6 A;  4IPA A;  4U69 A;  3MX6 A;  4FLJ A;  4JUQ A;  4EGE A;  4Z7M A;  2Q96 A;  2GU5 A;  3BIQ A;  4U73 A;  1QZY A;  1W2M A;  4RGZ 1;  1CHM A;  4IKT A;  2B3H A;  2BHD A;  2BWS A;  1KQ0 A;  2V3Y A;  4ZWO A;  3BIT A;  3FMR A;  2GG8 A;  2MAT A;  4FLK A;  2BH3 A;  5D6F A;  4B28 A;  3PKB A;  2OAZ A;  4U6E A;  4IU6 A;  1YW9 A;  3PKA A;  4U75 A;  3D27 A; 
#chains in the Genus database with same CATH topology
 1C22 A;  2P9A A;  2Q94 A;  3IU8 A;  2BN7 A;  2BWV A;  2Q95 A;  3MR1 A;  5CDE A;  1O0X A;  2GA2 A;  4FKC A;  3Q6D A;  2BWU A;  2P98 A;  2V3X A;  2EVO A;  5CDV A;  4HXX A;  2BWY A;  2GG5 A;  4IF7 A;  1WL9 A;  2EVM A;  4ZNG A;  3TAV A;  4U6Z A;  4U6J A;  4U71 A;  4RZY A;  4U6C A;  4IKS A;  4PV4 A;  2GU7 A;  2IW2 A;  2Q92 A;  2V3Z A;  2GGB A;  3TB5 A;  1QXW A;  5CNX A;  3PKE A;  2BWT A;  5D6E A;  5FCH A;  5CLS A;  2BWW A;  2GG9 A;  4KM3 A;  4OOK A;  2GTX A;  4U1B A;  1XGS A;  2B3L A;  1WN1 A;  2GG2 A;  5CIK A;  3IU9 A;  1YVM A;  1N51 A;  1QXZ A;  1R5H A;  1C27 A;  1KQ9 A;  4RZZ A;  3L7G A;  3RVA A;  4QR8 A;  1KP0 A;  2DFI A;  4ZWP A;  2ADU A;  2BHC A;  4A6W A;  2GU6 A;  4U6W A;  4IDY A;  2GG7 A;  4FO8 A;  2BWX A;  1A16 A;  1XGM A;  3FM3 A;  2V6C A;  2GGC A;  4FLI A;  2EVC A;  4FUK A;  3L24 A;  2P99 A;  4IKR A;  1WBQ A;  2EA4 A;  4PNC A;  4A6V A;  3IG4 A;  5FCF A;  2BHA A;  4R60 A;  2ZSG A;  1XGN A;  1JAW A;  3CB5 A;  5CDL A;  5JHU A;  2G6P A;  1XGO A;  3CTZ A;  1B59 A;  1C23 A;  1R5G A;  2B3K A;  4S2R P;  3S6B A;  4U76 A;  1W7V A;  2GZ5 A;  1XNZ A;  2NQ7 A;  3CB6 A;  2Q8K A;  1WLR A;  4FLL A;  1R58 A;  4U70 A;  5JI6 A;  1YW8 A;  2BB7 A;  2OKN A;  5JFR A;  4FO7 A;  2NQ6 A;  1YJ3 A;  3PKD A;  1C24 A;  2GU4 A;  3IU7 A;  4S2T P;  2HOW A;  1B6A A;  1BOA A;  2BHB A;  4IEC A;  4S01 A;  1C21 A;  1WKM A;  4IKU A;  5CE6 A;  3BIP A;  5E5B A;  3ROR A;  4ZWU A;  4MAT A;  1MAT A;  1BN5 A;  2GG3 A;  1Y1N A;  2Q93 A;  3FMQ A;  1QXY A;  2EA2 A;  2GG0 A;  4S00 A;  1WY2 A;  1PV9 A;  3MAT A;  1YW7 A;  3PKC A;  1M35 A;  1WL6 A;  4IPA A;  4U69 A;  3MX6 A;  4FLJ A;  4JUQ A;  4EGE A;  4Z7M A;  2Q96 A;  2GU5 A;  3BIQ A;  4U73 A;  1QZY A;  1W2M A;  4RGZ 1;  1CHM A;  4IKT A;  2B3H A;  2BHD A;  2BWS A;  1KQ0 A;  2V3Y A;  4ZWO A;  3BIT A;  3FMR A;  2GG8 A;  2MAT A;  4FLK A;  2BH3 A;  5D6F A;  4B28 A;  3PKB A;  2OAZ A;  4U6E A;  4IU6 A;  1YW9 A;  3PKA A;  4U75 A;  3D27 A; 
#chains in the Genus database with same CATH homology
 1C22 A;  2P9A A;  2Q94 A;  3IU8 A;  2BN7 A;  2BWV A;  2Q95 A;  3MR1 A;  5CDE A;  1O0X A;  2GA2 A;  4FKC A;  3Q6D A;  2BWU A;  2P98 A;  2V3X A;  2EVO A;  5CDV A;  4HXX A;  2BWY A;  2GG5 A;  4IF7 A;  1WL9 A;  2EVM A;  4ZNG A;  3TAV A;  4U6Z A;  4U6J A;  4U71 A;  4RZY A;  4U6C A;  4IKS A;  4PV4 A;  2GU7 A;  2IW2 A;  2Q92 A;  2V3Z A;  2GGB A;  3TB5 A;  1QXW A;  5CNX A;  3PKE A;  2BWT A;  5D6E A;  5FCH A;  5CLS A;  2BWW A;  2GG9 A;  4KM3 A;  4OOK A;  2GTX A;  4U1B A;  1XGS A;  2B3L A;  1WN1 A;  2GG2 A;  5CIK A;  3IU9 A;  1YVM A;  1N51 A;  1QXZ A;  1R5H A;  1C27 A;  1KQ9 A;  4RZZ A;  3L7G A;  3RVA A;  4QR8 A;  1KP0 A;  2DFI A;  4ZWP A;  2ADU A;  2BHC A;  4A6W A;  2GU6 A;  4U6W A;  4IDY A;  2GG7 A;  4FO8 A;  2BWX A;  1A16 A;  1XGM A;  3FM3 A;  2V6C A;  2GGC A;  4FLI A;  2EVC A;  4FUK A;  3L24 A;  2P99 A;  4IKR A;  1WBQ A;  2EA4 A;  4PNC A;  4A6V A;  3IG4 A;  5FCF A;  2BHA A;  4R60 A;  2ZSG A;  1XGN A;  1JAW A;  3CB5 A;  5CDL A;  5JHU A;  2G6P A;  1XGO A;  3CTZ A;  1B59 A;  1C23 A;  1R5G A;  2B3K A;  4S2R P;  3S6B A;  4U76 A;  1W7V A;  2GZ5 A;  1XNZ A;  2NQ7 A;  3CB6 A;  2Q8K A;  1WLR A;  4FLL A;  1R58 A;  4U70 A;  5JI6 A;  1YW8 A;  2BB7 A;  2OKN A;  5JFR A;  4FO7 A;  2NQ6 A;  1YJ3 A;  3PKD A;  1C24 A;  2GU4 A;  3IU7 A;  4S2T P;  2HOW A;  1B6A A;  1BOA A;  2BHB A;  4IEC A;  4S01 A;  1C21 A;  1WKM A;  4IKU A;  5CE6 A;  3BIP A;  5E5B A;  3ROR A;  4ZWU A;  4MAT A;  1MAT A;  1BN5 A;  2GG3 A;  1Y1N A;  2Q93 A;  3FMQ A;  1QXY A;  2EA2 A;  2GG0 A;  4S00 A;  1WY2 A;  1PV9 A;  3MAT A;  1YW7 A;  3PKC A;  1M35 A;  1WL6 A;  4IPA A;  4U69 A;  3MX6 A;  4FLJ A;  4JUQ A;  4EGE A;  4Z7M A;  2Q96 A;  2GU5 A;  3BIQ A;  4U73 A;  1QZY A;  1W2M A;  4RGZ 1;  1CHM A;  4IKT A;  2B3H A;  2BHD A;  2BWS A;  1KQ0 A;  2V3Y A;  4ZWO A;  3BIT A;  3FMR A;  2GG8 A;  2MAT A;  4FLK A;  2BH3 A;  5D6F A;  4B28 A;  3PKB A;  2OAZ A;  4U6E A;  4IU6 A;  1YW9 A;  3PKA A;  4U75 A;  3D27 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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