3IU9A

M. tuberculosis methionine aminopeptidase with ni inhibitor t07
Total Genus 89
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
89
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 89
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu9A01
4ZNGA 3RVAA 2BB7A 2B3HA 4S01A 1C24A 1WBQA 5JI6A 5JFRA 3MATA 2GU4A 4RGZ1 3L24A 2GZ5A 1WL6A 2Q94A 1M35A 4S2TP 4U71A 1KP0A 4IDYA 2V3XA 4MATA 4ZWOA 4FO8A 1QXZA 2P98A 2P99A 1KQ9A 1R5HA 2GGBA 4ZWPA 1XGOA 3S6BA 1C22A 5CE6A 2Q8KA 1O0XA 5CDVA 4U75A 2IW2A 2B3KA 3CB6A 3L7GA 4RZZA 5E5BA 2V3ZA 2OKNA 4A6WA 3Q6DA 3TAVA 4FKCA 2GU6A 4IPAA 2BWWA 2BWXA 3CTZA 2BHBA 2GG3A 2GG8A 3FMQA 1XGMA 2EVOA 2GU7A 1Y1NA 5FCFA 1XNZA 2P9AA 4U6ZA 5CNXA 4R60A 4U73A 1WKMA 4RZYA 5CIKA 2EVMA 4QR8A 4PV4A 5JHUA 4PNCA 3IG4A 3D27A 4EGEA 5FCHA 1QXYA 2GG7A 2B3LA 4Z7MA 1XGSA 1R5GA 1B6AA 4IECA 3MR1A 4U70A 3TB5A 3PKAA 3FM3A 2G6PA 4IKTA 1YW8A 3PKEA 4S2RP 3FMRA 4IU6A 2BHDA 2BN7A 4U6JA 2GTXA 2GU5A 1WY2A 1MATA 2BWUA 1CHMA 1YW7A 2BHCA 2GG9A 3CB5A 2DFIA 2Q96A 3RORA 4FO7A 2BH3A 4HXXA 1A16A 4U6WA 1WL9A 2BHAA 2GA2A 1WN1A 2HOWA 1C27A 3BIQA 2Q92A 1W2MA 2OAZA 4IF7A 1YW9A 2NQ7A 1XGNA 2BWYA 1KQ0A 4U76A 2Q95A 3MX6A 3PKBA 4IKUA 4A6VA 4B28A 4FLIA 5D6FA 1BOAA 2V6CA 4U6CA 2V3YA 1YJ3A 4U69A 2GGCA 1QZYA 2Q93A 1WLRA 4U6EA 2BWSA 2EA4A 3IU9A 5D6EA 1R58A 3IU7A 1C21A 2ADUA 2BWVA 2MATA 3BITA 4FLJA 4KM3A 2EA2A 3PKDA 4OOKA 4S00A 3BIPA 1B59A 1C23A 4IKSA 1N51A 2ZSGA 5CDEA 2BWTA 4IKRA 1BN5A 4JUQA 2EVCA 4U1BA 2GG5A 2GG2A 4FLKA 3IU8A 2GG0A 3PKCA 5CLSA 4ZWUA 4FUKA 5CDLA 1JAWA 1YVMA 4FLLA 1PV9A 1QXWA 1W7VA 2NQ6A
chains in the Genus database with same CATH superfamily
4ZNGA 3RVAA 2BB7A 2B3HA 4S01A 1C24A 1WBQA 5JI6A 5JFRA 3MATA 2GU4A 4RGZ1 3L24A 2GZ5A 1WL6A 2Q94A 1M35A 4S2TP 4U71A 1KP0A 4IDYA 2V3XA 4MATA 4ZWOA 4FO8A 1QXZA 2P98A 2P99A 1KQ9A 1R5HA 2GGBA 4ZWPA 1XGOA 3S6BA 1C22A 5CE6A 2Q8KA 1O0XA 5CDVA 4U75A 2IW2A 2B3KA 3CB6A 3L7GA 4RZZA 5E5BA 2V3ZA 2OKNA 4A6WA 3Q6DA 3TAVA 4FKCA 2GU6A 4IPAA 2BWWA 2BWXA 3CTZA 2BHBA 2GG3A 2GG8A 3FMQA 1XGMA 2EVOA 2GU7A 1Y1NA 5FCFA 1XNZA 2P9AA 4U6ZA 5CNXA 4R60A 4U73A 1WKMA 4RZYA 5CIKA 2EVMA 4QR8A 4PV4A 5JHUA 4PNCA 3IG4A 3D27A 4EGEA 5FCHA 1QXYA 2GG7A 2B3LA 4Z7MA 1XGSA 1R5GA 1B6AA 4IECA 3MR1A 4U70A 3TB5A 3PKAA 3FM3A 2G6PA 4IKTA 1YW8A 3PKEA 4S2RP 3FMRA 4IU6A 2BHDA 2BN7A 4U6JA 2GTXA 2GU5A 1WY2A 1MATA 2BWUA 1CHMA 1YW7A 2BHCA 2GG9A 3CB5A 2DFIA 2Q96A 3RORA 4FO7A 2BH3A 4HXXA 1A16A 4U6WA 1WL9A 2BHAA 2GA2A 1WN1A 2HOWA 1C27A 3BIQA 2Q92A 1W2MA 2OAZA 4IF7A 1YW9A 2NQ7A 1XGNA 2BWYA 1KQ0A 4U76A 2Q95A 3MX6A 3PKBA 4IKUA 4A6VA 4B28A 4FLIA 5D6FA 1BOAA 2V6CA 4U6CA 2V3YA 1YJ3A 4U69A 2GGCA 1QZYA 2Q93A 1WLRA 4U6EA 2BWSA 2EA4A 3IU9A 5D6EA 1R58A 3IU7A 1C21A 2ADUA 2BWVA 2MATA 3BITA 4FLJA 4KM3A 2EA2A 3PKDA 4OOKA 4S00A 3BIPA 1B59A 1C23A 4IKSA 1N51A 2ZSGA 5CDEA 2BWTA 4IKRA 1BN5A 4JUQA 2EVCA 4U1BA 2GG5A 2GG2A 4FLKA 3IU8A 2GG0A 3PKCA 5CLSA 4ZWUA 4FUKA 5CDLA 1JAWA 1YVMA 4FLLA 1PV9A 1QXWA 1W7VA 2NQ6A
chains in the Genus database with same CATH topology
4ZNGA 3RVAA 2BB7A 2B3HA 4S01A 1C24A 1WBQA 5JI6A 5JFRA 3MATA 2GU4A 4RGZ1 3L24A 2GZ5A 1WL6A 2Q94A 1M35A 4S2TP 4U71A 1KP0A 4IDYA 2V3XA 4MATA 4ZWOA 4FO8A 1QXZA 2P98A 2P99A 1KQ9A 1R5HA 2GGBA 4ZWPA 1XGOA 3S6BA 1C22A 5CE6A 2Q8KA 1O0XA 5CDVA 4U75A 2IW2A 2B3KA 3CB6A 3L7GA 4RZZA 5E5BA 2V3ZA 2OKNA 4A6WA 3Q6DA 3TAVA 4FKCA 2GU6A 4IPAA 2BWWA 2BWXA 3CTZA 2BHBA 2GG3A 2GG8A 3FMQA 1XGMA 2EVOA 2GU7A 1Y1NA 5FCFA 1XNZA 2P9AA 4U6ZA 5CNXA 4R60A 4U73A 1WKMA 4RZYA 5CIKA 2EVMA 4QR8A 4PV4A 5JHUA 4PNCA 3IG4A 3D27A 4EGEA 5FCHA 1QXYA 2GG7A 2B3LA 4Z7MA 1XGSA 1R5GA 1B6AA 4IECA 3MR1A 4U70A 3TB5A 3PKAA 3FM3A 2G6PA 4IKTA 1YW8A 3PKEA 4S2RP 3FMRA 4IU6A 2BHDA 2BN7A 4U6JA 2GTXA 2GU5A 1WY2A 1MATA 2BWUA 1CHMA 1YW7A 2BHCA 2GG9A 3CB5A 2DFIA 2Q96A 3RORA 4FO7A 2BH3A 4HXXA 1A16A 4U6WA 1WL9A 2BHAA 2GA2A 1WN1A 2HOWA 1C27A 3BIQA 2Q92A 1W2MA 2OAZA 4IF7A 1YW9A 2NQ7A 1XGNA 2BWYA 1KQ0A 4U76A 2Q95A 3MX6A 3PKBA 4IKUA 4A6VA 4B28A 4FLIA 5D6FA 1BOAA 2V6CA 4U6CA 2V3YA 1YJ3A 4U69A 2GGCA 1QZYA 2Q93A 1WLRA 4U6EA 2BWSA 2EA4A 3IU9A 5D6EA 1R58A 3IU7A 1C21A 2ADUA 2BWVA 2MATA 3BITA 4FLJA 4KM3A 2EA2A 3PKDA 4OOKA 4S00A 3BIPA 1B59A 1C23A 4IKSA 1N51A 2ZSGA 5CDEA 2BWTA 4IKRA 1BN5A 4JUQA 2EVCA 4U1BA 2GG5A 2GG2A 4FLKA 3IU8A 2GG0A 3PKCA 5CLSA 4ZWUA 4FUKA 5CDLA 1JAWA 1YVMA 4FLLA 1PV9A 1QXWA 1W7VA 2NQ6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZNG A;  3RVA A;  2BB7 A;  2B3H A;  4S01 A;  1C24 A;  1WBQ A;  5JI6 A;  5JFR A;  3MAT A;  2GU4 A;  4RGZ 1;  3L24 A;  2GZ5 A;  1WL6 A;  2Q94 A;  1M35 A;  4S2T P;  4U71 A;  1KP0 A;  4IDY A;  2V3X A;  4MAT A;  4ZWO A;  4FO8 A;  1QXZ A;  2P98 A;  2P99 A;  1KQ9 A;  1R5H A;  2GGB A;  4ZWP A;  1XGO A;  3S6B A;  1C22 A;  5CE6 A;  2Q8K A;  1O0X A;  5CDV A;  4U75 A;  2IW2 A;  2B3K A;  3CB6 A;  3L7G A;  4RZZ A;  5E5B A;  2V3Z A;  2OKN A;  4A6W A;  3Q6D A;  3TAV A;  4FKC A;  2GU6 A;  4IPA A;  2BWW A;  2BWX A;  3CTZ A;  2BHB A;  2GG3 A;  2GG8 A;  3FMQ A;  1XGM A;  2EVO A;  2GU7 A;  1Y1N A;  5FCF A;  1XNZ A;  2P9A A;  4U6Z A;  5CNX A;  4R60 A;  4U73 A;  1WKM A;  4RZY A;  5CIK A;  2EVM A;  4QR8 A;  4PV4 A;  5JHU A;  4PNC A;  3IG4 A;  3D27 A;  4EGE A;  5FCH A;  1QXY A;  2GG7 A;  2B3L A;  4Z7M A;  1XGS A;  1R5G A;  1B6A A;  4IEC A;  3MR1 A;  4U70 A;  3TB5 A;  3PKA A;  3FM3 A;  2G6P A;  4IKT A;  1YW8 A;  3PKE A;  4S2R P;  3FMR A;  4IU6 A;  2BHD A;  2BN7 A;  4U6J A;  2GTX A;  2GU5 A;  1WY2 A;  1MAT A;  2BWU A;  1CHM A;  1YW7 A;  2BHC A;  2GG9 A;  3CB5 A;  2DFI A;  2Q96 A;  3ROR A;  4FO7 A;  2BH3 A;  4HXX A;  1A16 A;  4U6W A;  1WL9 A;  2BHA A;  2GA2 A;  1WN1 A;  2HOW A;  1C27 A;  3BIQ A;  2Q92 A;  1W2M A;  2OAZ A;  4IF7 A;  1YW9 A;  2NQ7 A;  1XGN A;  2BWY A;  1KQ0 A;  4U76 A;  2Q95 A;  3MX6 A;  3PKB A;  4IKU A;  4A6V A;  4B28 A;  4FLI A;  5D6F A;  1BOA A;  2V6C A;  4U6C A;  2V3Y A;  1YJ3 A;  4U69 A;  2GGC A;  1QZY A;  2Q93 A;  1WLR A;  4U6E A;  2BWS A;  2EA4 A;  3IU9 A;  5D6E A;  1R58 A;  3IU7 A;  1C21 A;  2ADU A;  2BWV A;  2MAT A;  3BIT A;  4FLJ A;  4KM3 A;  2EA2 A;  3PKD A;  4OOK A;  4S00 A;  3BIP A;  1B59 A;  1C23 A;  4IKS A;  1N51 A;  2ZSG A;  5CDE A;  2BWT A;  4IKR A;  1BN5 A;  4JUQ A;  2EVC A;  4U1B A;  2GG5 A;  2GG2 A;  4FLK A;  3IU8 A;  2GG0 A;  3PKC A;  5CLS A;  4ZWU A;  4FUK A;  5CDL A;  1JAW A;  1YVM A;  4FLL A;  1PV9 A;  1QXW A;  1W7V A;  2NQ6 A; 
#chains in the Genus database with same CATH topology
 4ZNG A;  3RVA A;  2BB7 A;  2B3H A;  4S01 A;  1C24 A;  1WBQ A;  5JI6 A;  5JFR A;  3MAT A;  2GU4 A;  4RGZ 1;  3L24 A;  2GZ5 A;  1WL6 A;  2Q94 A;  1M35 A;  4S2T P;  4U71 A;  1KP0 A;  4IDY A;  2V3X A;  4MAT A;  4ZWO A;  4FO8 A;  1QXZ A;  2P98 A;  2P99 A;  1KQ9 A;  1R5H A;  2GGB A;  4ZWP A;  1XGO A;  3S6B A;  1C22 A;  5CE6 A;  2Q8K A;  1O0X A;  5CDV A;  4U75 A;  2IW2 A;  2B3K A;  3CB6 A;  3L7G A;  4RZZ A;  5E5B A;  2V3Z A;  2OKN A;  4A6W A;  3Q6D A;  3TAV A;  4FKC A;  2GU6 A;  4IPA A;  2BWW A;  2BWX A;  3CTZ A;  2BHB A;  2GG3 A;  2GG8 A;  3FMQ A;  1XGM A;  2EVO A;  2GU7 A;  1Y1N A;  5FCF A;  1XNZ A;  2P9A A;  4U6Z A;  5CNX A;  4R60 A;  4U73 A;  1WKM A;  4RZY A;  5CIK A;  2EVM A;  4QR8 A;  4PV4 A;  5JHU A;  4PNC A;  3IG4 A;  3D27 A;  4EGE A;  5FCH A;  1QXY A;  2GG7 A;  2B3L A;  4Z7M A;  1XGS A;  1R5G A;  1B6A A;  4IEC A;  3MR1 A;  4U70 A;  3TB5 A;  3PKA A;  3FM3 A;  2G6P A;  4IKT A;  1YW8 A;  3PKE A;  4S2R P;  3FMR A;  4IU6 A;  2BHD A;  2BN7 A;  4U6J A;  2GTX A;  2GU5 A;  1WY2 A;  1MAT A;  2BWU A;  1CHM A;  1YW7 A;  2BHC A;  2GG9 A;  3CB5 A;  2DFI A;  2Q96 A;  3ROR A;  4FO7 A;  2BH3 A;  4HXX A;  1A16 A;  4U6W A;  1WL9 A;  2BHA A;  2GA2 A;  1WN1 A;  2HOW A;  1C27 A;  3BIQ A;  2Q92 A;  1W2M A;  2OAZ A;  4IF7 A;  1YW9 A;  2NQ7 A;  1XGN A;  2BWY A;  1KQ0 A;  4U76 A;  2Q95 A;  3MX6 A;  3PKB A;  4IKU A;  4A6V A;  4B28 A;  4FLI A;  5D6F A;  1BOA A;  2V6C A;  4U6C A;  2V3Y A;  1YJ3 A;  4U69 A;  2GGC A;  1QZY A;  2Q93 A;  1WLR A;  4U6E A;  2BWS A;  2EA4 A;  3IU9 A;  5D6E A;  1R58 A;  3IU7 A;  1C21 A;  2ADU A;  2BWV A;  2MAT A;  3BIT A;  4FLJ A;  4KM3 A;  2EA2 A;  3PKD A;  4OOK A;  4S00 A;  3BIP A;  1B59 A;  1C23 A;  4IKS A;  1N51 A;  2ZSG A;  5CDE A;  2BWT A;  4IKR A;  1BN5 A;  4JUQ A;  2EVC A;  4U1B A;  2GG5 A;  2GG2 A;  4FLK A;  3IU8 A;  2GG0 A;  3PKC A;  5CLS A;  4ZWU A;  4FUK A;  5CDL A;  1JAW A;  1YVM A;  4FLL A;  1PV9 A;  1QXW A;  1W7V A;  2NQ6 A; 
#chains in the Genus database with same CATH homology
 4ZNG A;  3RVA A;  2BB7 A;  2B3H A;  4S01 A;  1C24 A;  1WBQ A;  5JI6 A;  5JFR A;  3MAT A;  2GU4 A;  4RGZ 1;  3L24 A;  2GZ5 A;  1WL6 A;  2Q94 A;  1M35 A;  4S2T P;  4U71 A;  1KP0 A;  4IDY A;  2V3X A;  4MAT A;  4ZWO A;  4FO8 A;  1QXZ A;  2P98 A;  2P99 A;  1KQ9 A;  1R5H A;  2GGB A;  4ZWP A;  1XGO A;  3S6B A;  1C22 A;  5CE6 A;  2Q8K A;  1O0X A;  5CDV A;  4U75 A;  2IW2 A;  2B3K A;  3CB6 A;  3L7G A;  4RZZ A;  5E5B A;  2V3Z A;  2OKN A;  4A6W A;  3Q6D A;  3TAV A;  4FKC A;  2GU6 A;  4IPA A;  2BWW A;  2BWX A;  3CTZ A;  2BHB A;  2GG3 A;  2GG8 A;  3FMQ A;  1XGM A;  2EVO A;  2GU7 A;  1Y1N A;  5FCF A;  1XNZ A;  2P9A A;  4U6Z A;  5CNX A;  4R60 A;  4U73 A;  1WKM A;  4RZY A;  5CIK A;  2EVM A;  4QR8 A;  4PV4 A;  5JHU A;  4PNC A;  3IG4 A;  3D27 A;  4EGE A;  5FCH A;  1QXY A;  2GG7 A;  2B3L A;  4Z7M A;  1XGS A;  1R5G A;  1B6A A;  4IEC A;  3MR1 A;  4U70 A;  3TB5 A;  3PKA A;  3FM3 A;  2G6P A;  4IKT A;  1YW8 A;  3PKE A;  4S2R P;  3FMR A;  4IU6 A;  2BHD A;  2BN7 A;  4U6J A;  2GTX A;  2GU5 A;  1WY2 A;  1MAT A;  2BWU A;  1CHM A;  1YW7 A;  2BHC A;  2GG9 A;  3CB5 A;  2DFI A;  2Q96 A;  3ROR A;  4FO7 A;  2BH3 A;  4HXX A;  1A16 A;  4U6W A;  1WL9 A;  2BHA A;  2GA2 A;  1WN1 A;  2HOW A;  1C27 A;  3BIQ A;  2Q92 A;  1W2M A;  2OAZ A;  4IF7 A;  1YW9 A;  2NQ7 A;  1XGN A;  2BWY A;  1KQ0 A;  4U76 A;  2Q95 A;  3MX6 A;  3PKB A;  4IKU A;  4A6V A;  4B28 A;  4FLI A;  5D6F A;  1BOA A;  2V6C A;  4U6C A;  2V3Y A;  1YJ3 A;  4U69 A;  2GGC A;  1QZY A;  2Q93 A;  1WLR A;  4U6E A;  2BWS A;  2EA4 A;  3IU9 A;  5D6E A;  1R58 A;  3IU7 A;  1C21 A;  2ADU A;  2BWV A;  2MAT A;  3BIT A;  4FLJ A;  4KM3 A;  2EA2 A;  3PKD A;  4OOK A;  4S00 A;  3BIP A;  1B59 A;  1C23 A;  4IKS A;  1N51 A;  2ZSG A;  5CDE A;  2BWT A;  4IKR A;  1BN5 A;  4JUQ A;  2EVC A;  4U1B A;  2GG5 A;  2GG2 A;  4FLK A;  3IU8 A;  2GG0 A;  3PKC A;  5CLS A;  4ZWU A;  4FUK A;  5CDL A;  1JAW A;  1YVM A;  4FLL A;  1PV9 A;  1QXW A;  1W7V A;  2NQ6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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