3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
1C27A 1YVMA 3IU7A 2BHDA 3TAVA 1WY2A 2ZSGA 4U6EA 3BITA 2GZ5A 3PKDA 2BWXA 2GU5A 4FLLA 4U6WA 3FM3A 4IKSA 1BOAA 2GG2A 1QXYA 1KP0A 4U6CA 1R5GA 4U76A 2Q93A 2BN7A 4FKCA 4U69A 1MATA 2HOWA 4U71A 2GTXA 4U70A 2BWVA 4B28A 1R58A 1WL6A 3IG4A 2GGCA 1JAWA 1WBQA 2GU7A 5JHUA 4U75A 1W7VA 4Z7MA 3D27A 4PV4A 5CDEA 4ZWUA 2BWYA 4FO7A 2GU6A 4IKUA 4JUQA 2V3ZA 2GG7A 4S2TP 1R5HA 5D6EA 4EGEA 3PKAA 2GU4A 3TB5A 1KQ9A 4OOKA 1YJ3A 4MATA 4IKTA 1M35A 4IECA 1QXZA 2Q92A 2GG5A 3PKCA 4IF7A 4ZWPA 2GG3A 2P99A 1O0XA 2BH3A 1C23A 4FUKA 3MR1A 1XNZA 2GG8A 1B6AA 2NQ7A 4PNCA 1C22A 3IU8A 4RGZ1 3CB5A 4FLIA 4U6ZA 4HXXA 4S00A 1N51A 5JI6A 4QR8A 2IW2A 2Q96A 2B3HA 3CTZA 1WLRA 3FMQA 2EA2A 1YW7A 2EVMA 5FCFA 3L24A 1QZYA 1XGOA 2NQ6A 2Q8KA 2MATA 5D6FA 4FO8A 5E5BA 1WN1A 3FMRA 4IU6A 1WKMA 1CHMA 2B3KA 2BB7A 3RVAA 2V3YA 5CDLA 2BWWA 2EA4A 2BWTA 1YW9A 2OAZA 3IU9A 4ZNGA 2V3XA 5CNXA 4S01A 5CE6A 1W2MA 2EVCA 3RORA 2G6PA 2BHBA 4IPAA 1PV9A 5CDVA 5FCHA 3MX6A 1XGMA 1B59A 1QXWA 3BIQA 4IKRA 2OKNA 2Q95A 2BHCA 1XGSA 4FLJA 4U1BA 5JFRA 1KQ0A 3Q6DA 2GG9A 3BIPA 1C21A 3PKBA 4R60A 2Q94A 3PKEA 5CLSA 2GA2A 4RZZA 2V6CA 4U6JA 2DFIA 4ZWOA 4IDYA 4A6WA 2GG0A 1WL9A 3MATA 2ADUA 1C24A 1A16A 1YW8A 3L7GA 2BWSA 4U73A 4RZYA 5CIKA 1Y1NA 1XGNA 2B3LA 2BHAA 4A6VA 3S6BA 4FLKA 4KM3A 2BWUA 3CB6A 2P9AA 2EVOA 2GGBA 1BN5A 4S2RP 2P98A
chains in the Genus database with same CATH superfamily
1C27A 1YVMA 3IU7A 2BHDA 3TAVA 1WY2A 2ZSGA 4U6EA 3BITA 2GZ5A 3PKDA 2BWXA 2GU5A 4FLLA 4U6WA 3FM3A 4IKSA 1BOAA 2GG2A 1QXYA 1KP0A 4U6CA 1R5GA 4U76A 2Q93A 2BN7A 4FKCA 4U69A 1MATA 2HOWA 4U71A 2GTXA 4U70A 2BWVA 4B28A 1R58A 1WL6A 3IG4A 2GGCA 1JAWA 1WBQA 2GU7A 5JHUA 4U75A 1W7VA 4Z7MA 3D27A 4PV4A 5CDEA 4ZWUA 2BWYA 4FO7A 2GU6A 4IKUA 4JUQA 2V3ZA 2GG7A 4S2TP 1R5HA 5D6EA 4EGEA 3PKAA 2GU4A 3TB5A 1KQ9A 4OOKA 1YJ3A 4MATA 4IKTA 1M35A 4IECA 1QXZA 2Q92A 2GG5A 3PKCA 4IF7A 4ZWPA 2GG3A 2P99A 1O0XA 2BH3A 1C23A 4FUKA 3MR1A 1XNZA 2GG8A 1B6AA 2NQ7A 4PNCA 1C22A 3IU8A 4RGZ1 3CB5A 4FLIA 4U6ZA 4HXXA 4S00A 1N51A 5JI6A 4QR8A 2IW2A 2Q96A 2B3HA 3CTZA 1WLRA 3FMQA 2EA2A 1YW7A 2EVMA 5FCFA 3L24A 1QZYA 1XGOA 2NQ6A 2Q8KA 2MATA 5D6FA 4FO8A 5E5BA 1WN1A 3FMRA 4IU6A 1WKMA 1CHMA 2B3KA 2BB7A 3RVAA 2V3YA 5CDLA 2BWWA 2EA4A 2BWTA 1YW9A 2OAZA 3IU9A 4ZNGA 2V3XA 5CNXA 4S01A 5CE6A 1W2MA 2EVCA 3RORA 2G6PA 2BHBA 4IPAA 1PV9A 5CDVA 5FCHA 3MX6A 1XGMA 1B59A 1QXWA 3BIQA 4IKRA 2OKNA 2Q95A 2BHCA 1XGSA 4FLJA 4U1BA 5JFRA 1KQ0A 3Q6DA 2GG9A 3BIPA 1C21A 3PKBA 4R60A 2Q94A 3PKEA 5CLSA 2GA2A 4RZZA 2V6CA 4U6JA 2DFIA 4ZWOA 4IDYA 4A6WA 2GG0A 1WL9A 3MATA 2ADUA 1C24A 1A16A 1YW8A 3L7GA 2BWSA 4U73A 4RZYA 5CIKA 1Y1NA 1XGNA 2B3LA 2BHAA 4A6VA 3S6BA 4FLKA 4KM3A 2BWUA 3CB6A 2P9AA 2EVOA 2GGBA 1BN5A 4S2RP 2P98A
chains in the Genus database with same CATH topology
1C27A 1YVMA 3IU7A 2BHDA 3TAVA 1WY2A 2ZSGA 4U6EA 3BITA 2GZ5A 3PKDA 2BWXA 2GU5A 4FLLA 4U6WA 3FM3A 4IKSA 1BOAA 2GG2A 1QXYA 1KP0A 4U6CA 1R5GA 4U76A 2Q93A 2BN7A 4FKCA 4U69A 1MATA 2HOWA 4U71A 2GTXA 4U70A 2BWVA 4B28A 1R58A 1WL6A 3IG4A 2GGCA 1JAWA 1WBQA 2GU7A 5JHUA 4U75A 1W7VA 4Z7MA 3D27A 4PV4A 5CDEA 4ZWUA 2BWYA 4FO7A 2GU6A 4IKUA 4JUQA 2V3ZA 2GG7A 4S2TP 1R5HA 5D6EA 4EGEA 3PKAA 2GU4A 3TB5A 1KQ9A 4OOKA 1YJ3A 4MATA 4IKTA 1M35A 4IECA 1QXZA 2Q92A 2GG5A 3PKCA 4IF7A 4ZWPA 2GG3A 2P99A 1O0XA 2BH3A 1C23A 4FUKA 3MR1A 1XNZA 2GG8A 1B6AA 2NQ7A 4PNCA 1C22A 3IU8A 4RGZ1 3CB5A 4FLIA 4U6ZA 4HXXA 4S00A 1N51A 5JI6A 4QR8A 2IW2A 2Q96A 2B3HA 3CTZA 1WLRA 3FMQA 2EA2A 1YW7A 2EVMA 5FCFA 3L24A 1QZYA 1XGOA 2NQ6A 2Q8KA 2MATA 5D6FA 4FO8A 5E5BA 1WN1A 3FMRA 4IU6A 1WKMA 1CHMA 2B3KA 2BB7A 3RVAA 2V3YA 5CDLA 2BWWA 2EA4A 2BWTA 1YW9A 2OAZA 3IU9A 4ZNGA 2V3XA 5CNXA 4S01A 5CE6A 1W2MA 2EVCA 3RORA 2G6PA 2BHBA 4IPAA 1PV9A 5CDVA 5FCHA 3MX6A 1XGMA 1B59A 1QXWA 3BIQA 4IKRA 2OKNA 2Q95A 2BHCA 1XGSA 4FLJA 4U1BA 5JFRA 1KQ0A 3Q6DA 2GG9A 3BIPA 1C21A 3PKBA 4R60A 2Q94A 3PKEA 5CLSA 2GA2A 4RZZA 2V6CA 4U6JA 2DFIA 4ZWOA 4IDYA 4A6WA 2GG0A 1WL9A 3MATA 2ADUA 1C24A 1A16A 1YW8A 3L7GA 2BWSA 4U73A 4RZYA 5CIKA 1Y1NA 1XGNA 2B3LA 2BHAA 4A6VA 3S6BA 4FLKA 4KM3A 2BWUA 3CB6A 2P9AA 2EVOA 2GGBA 1BN5A 4S2RP 2P98A
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 1C27 A;  1YVM A;  3IU7 A;  2BHD A;  3TAV A;  1WY2 A;  2ZSG A;  4U6E A;  3BIT A;  2GZ5 A;  3PKD A;  2BWX A;  2GU5 A;  4FLL A;  4U6W A;  3FM3 A;  4IKS A;  1BOA A;  2GG2 A;  1QXY A;  1KP0 A;  4U6C A;  1R5G A;  4U76 A;  2Q93 A;  2BN7 A;  4FKC A;  4U69 A;  1MAT A;  2HOW A;  4U71 A;  2GTX A;  4U70 A;  2BWV A;  4B28 A;  1R58 A;  1WL6 A;  3IG4 A;  2GGC A;  1JAW A;  1WBQ A;  2GU7 A;  5JHU A;  4U75 A;  1W7V A;  4Z7M A;  3D27 A;  4PV4 A;  5CDE A;  4ZWU A;  2BWY A;  4FO7 A;  2GU6 A;  4IKU A;  4JUQ A;  2V3Z A;  2GG7 A;  4S2T P;  1R5H A;  5D6E A;  4EGE A;  3PKA A;  2GU4 A;  3TB5 A;  1KQ9 A;  4OOK A;  1YJ3 A;  4MAT A;  4IKT A;  1M35 A;  4IEC A;  1QXZ A;  2Q92 A;  2GG5 A;  3PKC A;  4IF7 A;  4ZWP A;  2GG3 A;  2P99 A;  1O0X A;  2BH3 A;  1C23 A;  4FUK A;  3MR1 A;  1XNZ A;  2GG8 A;  1B6A A;  2NQ7 A;  4PNC A;  1C22 A;  3IU8 A;  4RGZ 1;  3CB5 A;  4FLI A;  4U6Z A;  4HXX A;  4S00 A;  1N51 A;  5JI6 A;  4QR8 A;  2IW2 A;  2Q96 A;  2B3H A;  3CTZ A;  1WLR A;  3FMQ A;  2EA2 A;  1YW7 A;  2EVM A;  5FCF A;  3L24 A;  1QZY A;  1XGO A;  2NQ6 A;  2Q8K A;  2MAT A;  5D6F A;  4FO8 A;  5E5B A;  1WN1 A;  3FMR A;  4IU6 A;  1WKM A;  1CHM A;  2B3K A;  2BB7 A;  3RVA A;  2V3Y A;  5CDL A;  2BWW A;  2EA4 A;  2BWT A;  1YW9 A;  2OAZ A;  3IU9 A;  4ZNG A;  2V3X A;  5CNX A;  4S01 A;  5CE6 A;  1W2M A;  2EVC A;  3ROR A;  2G6P A;  2BHB A;  4IPA A;  1PV9 A;  5CDV A;  5FCH A;  3MX6 A;  1XGM A;  1B59 A;  1QXW A;  3BIQ A;  4IKR A;  2OKN A;  2Q95 A;  2BHC A;  1XGS A;  4FLJ A;  4U1B A;  5JFR A;  1KQ0 A;  3Q6D A;  2GG9 A;  3BIP A;  1C21 A;  3PKB A;  4R60 A;  2Q94 A;  3PKE A;  5CLS A;  2GA2 A;  4RZZ A;  2V6C A;  4U6J A;  2DFI A;  4ZWO A;  4IDY A;  4A6W A;  2GG0 A;  1WL9 A;  3MAT A;  2ADU A;  1C24 A;  1A16 A;  1YW8 A;  3L7G A;  2BWS A;  4U73 A;  4RZY A;  5CIK A;  1Y1N A;  1XGN A;  2B3L A;  2BHA A;  4A6V A;  3S6B A;  4FLK A;  4KM3 A;  2BWU A;  3CB6 A;  2P9A A;  2EVO A;  2GGB A;  1BN5 A;  4S2R P;  2P98 A; 
#chains in the Genus database with same CATH topology
 1C27 A;  1YVM A;  3IU7 A;  2BHD A;  3TAV A;  1WY2 A;  2ZSG A;  4U6E A;  3BIT A;  2GZ5 A;  3PKD A;  2BWX A;  2GU5 A;  4FLL A;  4U6W A;  3FM3 A;  4IKS A;  1BOA A;  2GG2 A;  1QXY A;  1KP0 A;  4U6C A;  1R5G A;  4U76 A;  2Q93 A;  2BN7 A;  4FKC A;  4U69 A;  1MAT A;  2HOW A;  4U71 A;  2GTX A;  4U70 A;  2BWV A;  4B28 A;  1R58 A;  1WL6 A;  3IG4 A;  2GGC A;  1JAW A;  1WBQ A;  2GU7 A;  5JHU A;  4U75 A;  1W7V A;  4Z7M A;  3D27 A;  4PV4 A;  5CDE A;  4ZWU A;  2BWY A;  4FO7 A;  2GU6 A;  4IKU A;  4JUQ A;  2V3Z A;  2GG7 A;  4S2T P;  1R5H A;  5D6E A;  4EGE A;  3PKA A;  2GU4 A;  3TB5 A;  1KQ9 A;  4OOK A;  1YJ3 A;  4MAT A;  4IKT A;  1M35 A;  4IEC A;  1QXZ A;  2Q92 A;  2GG5 A;  3PKC A;  4IF7 A;  4ZWP A;  2GG3 A;  2P99 A;  1O0X A;  2BH3 A;  1C23 A;  4FUK A;  3MR1 A;  1XNZ A;  2GG8 A;  1B6A A;  2NQ7 A;  4PNC A;  1C22 A;  3IU8 A;  4RGZ 1;  3CB5 A;  4FLI A;  4U6Z A;  4HXX A;  4S00 A;  1N51 A;  5JI6 A;  4QR8 A;  2IW2 A;  2Q96 A;  2B3H A;  3CTZ A;  1WLR A;  3FMQ A;  2EA2 A;  1YW7 A;  2EVM A;  5FCF A;  3L24 A;  1QZY A;  1XGO A;  2NQ6 A;  2Q8K A;  2MAT A;  5D6F A;  4FO8 A;  5E5B A;  1WN1 A;  3FMR A;  4IU6 A;  1WKM A;  1CHM A;  2B3K A;  2BB7 A;  3RVA A;  2V3Y A;  5CDL A;  2BWW A;  2EA4 A;  2BWT A;  1YW9 A;  2OAZ A;  3IU9 A;  4ZNG A;  2V3X A;  5CNX A;  4S01 A;  5CE6 A;  1W2M A;  2EVC A;  3ROR A;  2G6P A;  2BHB A;  4IPA A;  1PV9 A;  5CDV A;  5FCH A;  3MX6 A;  1XGM A;  1B59 A;  1QXW A;  3BIQ A;  4IKR A;  2OKN A;  2Q95 A;  2BHC A;  1XGS A;  4FLJ A;  4U1B A;  5JFR A;  1KQ0 A;  3Q6D A;  2GG9 A;  3BIP A;  1C21 A;  3PKB A;  4R60 A;  2Q94 A;  3PKE A;  5CLS A;  2GA2 A;  4RZZ A;  2V6C A;  4U6J A;  2DFI A;  4ZWO A;  4IDY A;  4A6W A;  2GG0 A;  1WL9 A;  3MAT A;  2ADU A;  1C24 A;  1A16 A;  1YW8 A;  3L7G A;  2BWS A;  4U73 A;  4RZY A;  5CIK A;  1Y1N A;  1XGN A;  2B3L A;  2BHA A;  4A6V A;  3S6B A;  4FLK A;  4KM3 A;  2BWU A;  3CB6 A;  2P9A A;  2EVO A;  2GGB A;  1BN5 A;  4S2R P;  2P98 A; 
#chains in the Genus database with same CATH homology
 1C27 A;  1YVM A;  3IU7 A;  2BHD A;  3TAV A;  1WY2 A;  2ZSG A;  4U6E A;  3BIT A;  2GZ5 A;  3PKD A;  2BWX A;  2GU5 A;  4FLL A;  4U6W A;  3FM3 A;  4IKS A;  1BOA A;  2GG2 A;  1QXY A;  1KP0 A;  4U6C A;  1R5G A;  4U76 A;  2Q93 A;  2BN7 A;  4FKC A;  4U69 A;  1MAT A;  2HOW A;  4U71 A;  2GTX A;  4U70 A;  2BWV A;  4B28 A;  1R58 A;  1WL6 A;  3IG4 A;  2GGC A;  1JAW A;  1WBQ A;  2GU7 A;  5JHU A;  4U75 A;  1W7V A;  4Z7M A;  3D27 A;  4PV4 A;  5CDE A;  4ZWU A;  2BWY A;  4FO7 A;  2GU6 A;  4IKU A;  4JUQ A;  2V3Z A;  2GG7 A;  4S2T P;  1R5H A;  5D6E A;  4EGE A;  3PKA A;  2GU4 A;  3TB5 A;  1KQ9 A;  4OOK A;  1YJ3 A;  4MAT A;  4IKT A;  1M35 A;  4IEC A;  1QXZ A;  2Q92 A;  2GG5 A;  3PKC A;  4IF7 A;  4ZWP A;  2GG3 A;  2P99 A;  1O0X A;  2BH3 A;  1C23 A;  4FUK A;  3MR1 A;  1XNZ A;  2GG8 A;  1B6A A;  2NQ7 A;  4PNC A;  1C22 A;  3IU8 A;  4RGZ 1;  3CB5 A;  4FLI A;  4U6Z A;  4HXX A;  4S00 A;  1N51 A;  5JI6 A;  4QR8 A;  2IW2 A;  2Q96 A;  2B3H A;  3CTZ A;  1WLR A;  3FMQ A;  2EA2 A;  1YW7 A;  2EVM A;  5FCF A;  3L24 A;  1QZY A;  1XGO A;  2NQ6 A;  2Q8K A;  2MAT A;  5D6F A;  4FO8 A;  5E5B A;  1WN1 A;  3FMR A;  4IU6 A;  1WKM A;  1CHM A;  2B3K A;  2BB7 A;  3RVA A;  2V3Y A;  5CDL A;  2BWW A;  2EA4 A;  2BWT A;  1YW9 A;  2OAZ A;  3IU9 A;  4ZNG A;  2V3X A;  5CNX A;  4S01 A;  5CE6 A;  1W2M A;  2EVC A;  3ROR A;  2G6P A;  2BHB A;  4IPA A;  1PV9 A;  5CDV A;  5FCH A;  3MX6 A;  1XGM A;  1B59 A;  1QXW A;  3BIQ A;  4IKR A;  2OKN A;  2Q95 A;  2BHC A;  1XGS A;  4FLJ A;  4U1B A;  5JFR A;  1KQ0 A;  3Q6D A;  2GG9 A;  3BIP A;  1C21 A;  3PKB A;  4R60 A;  2Q94 A;  3PKE A;  5CLS A;  2GA2 A;  4RZZ A;  2V6C A;  4U6J A;  2DFI A;  4ZWO A;  4IDY A;  4A6W A;  2GG0 A;  1WL9 A;  3MAT A;  2ADU A;  1C24 A;  1A16 A;  1YW8 A;  3L7G A;  2BWS A;  4U73 A;  4RZY A;  5CIK A;  1Y1N A;  1XGN A;  2B3L A;  2BHA A;  4A6V A;  3S6B A;  4FLK A;  4KM3 A;  2BWU A;  3CB6 A;  2P9A A;  2EVO A;  2GGB A;  1BN5 A;  4S2R P;  2P98 A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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