3RORA

Crystal structure of c105s mutant of mycobacterium tuberculosis methionine aminopeptidase
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCSTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure of C105S mutant of Mycobacterium tuberculosis methionine aminopeptidase
rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 85
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-04-26

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3rorA01
3S6BA 2OKNA 1C21A 3IU7A 2EVMA 5CDLA 4IF7A 4FLJA 4U75A 2BWWA 1XGMA 1KQ0A 1Y1NA 3TAVA 1XGOA 3BIQA 1XGNA 2ZSGA 4S01A 1YW7A 2GG0A 2GG5A 1B6AA 1QZYA 4FO8A 4U6ZA 3MATA 5CE6A 3FMRA 4ZWUA 3IU8A 4MATA 1R58A 2GGBA 2P99A 4PNCA 1C23A 4U73A 4FLIA 4U69A 2GGCA 4ZWPA 2B3HA 2GU4A 2NQ7A 3IG4A 3FM3A 2V3XA 1XGSA 4U71A 4EGEA 2BHCA 4U6WA 2GU5A 4IPAA 2BWXA 2GG3A 5E5BA 1BN5A 2BHAA 1YJ3A 4IDYA 1CHMA 4IKRA 4U1BA 2P98A 4KM3A 5CDVA 4U70A 2GTXA 4FLKA 5D6FA 2BWVA 2BWUA 1XNZA 3L7GA 1A16A 1W2MA 2IW2A 2Q96A 2Q93A 2EVCA 2GA2A 2GZ5A 2Q8KA 3PKAA 4A6WA 4S2RP 1WLRA 2Q94A 1WY2A 4ZWOA 2B3LA 3PKBA 5JHUA 5JI6A 2GG7A 2GG2A 2BB7A 3PKCA 2BWYA 4S00A 4ZNGA 2EA2A 1WKMA 4FO7A 1WBQA 1YW9A 1QXZA 3IU9A 1MATA 1R5HA 4IU6A 4U6EA 1WL9A 2HOWA 2BHBA 2G6PA 1B59A 1WL6A 1R5GA 3MR1A 4IKSA 4OOKA 1C22A 1QXWA 2P9AA 3RVAA 3PKEA 5CDEA 4R60A 4FKCA 2BWTA 4HXXA 4U6CA 1PV9A 2GG8A 2Q92A 5CNXA 3D27A 3CB6A 1KP0A 4S2TP 4IKTA 4U6JA 3CB5A 3BIPA 1BOAA 2DFIA 4JUQA 2V3ZA 3FMQA 2MATA 5JFRA 1JAWA 2Q95A 1N51A 1W7VA 4FUKA 4IECA 1YVMA 2B3KA 4RZYA 4FLLA 2BHDA 4IKUA 2OAZA 5CLSA 4U76A 2V6CA 2BH3A 3L24A 2GG9A 4PV4A 1M35A 5CIKA 4RZZA 4B28A 2GU7A 1O0XA 5D6EA 1WN1A 2GU6A 3Q6DA 1YW8A 2NQ6A 2BWSA 3BITA 2ADUA 3MX6A 3PKDA 3TB5A 2EVOA 2V3YA 4RGZ1 4QR8A 1QXYA 1C27A 2EA4A 1C24A 5FCHA 4A6VA 5FCFA 3CTZA 2BN7A 3RORA 4Z7MA 1KQ9A
chains in the Genus database with same CATH superfamily
3S6BA 2OKNA 1C21A 3IU7A 2EVMA 5CDLA 4IF7A 4FLJA 4U75A 2BWWA 1XGMA 1KQ0A 1Y1NA 3TAVA 1XGOA 3BIQA 1XGNA 2ZSGA 4S01A 1YW7A 2GG0A 2GG5A 1B6AA 1QZYA 4FO8A 4U6ZA 3MATA 5CE6A 3FMRA 4ZWUA 3IU8A 4MATA 1R58A 2GGBA 2P99A 4PNCA 1C23A 4U73A 4FLIA 4U69A 2GGCA 4ZWPA 2B3HA 2GU4A 2NQ7A 3IG4A 3FM3A 2V3XA 1XGSA 4U71A 4EGEA 2BHCA 4U6WA 2GU5A 4IPAA 2BWXA 2GG3A 5E5BA 1BN5A 2BHAA 1YJ3A 4IDYA 1CHMA 4IKRA 4U1BA 2P98A 4KM3A 5CDVA 4U70A 2GTXA 4FLKA 5D6FA 2BWVA 2BWUA 1XNZA 3L7GA 1A16A 1W2MA 2IW2A 2Q96A 2Q93A 2EVCA 2GA2A 2GZ5A 2Q8KA 3PKAA 4A6WA 4S2RP 1WLRA 2Q94A 1WY2A 4ZWOA 2B3LA 3PKBA 5JHUA 5JI6A 2GG7A 2GG2A 2BB7A 3PKCA 2BWYA 4S00A 4ZNGA 2EA2A 1WKMA 4FO7A 1WBQA 1YW9A 1QXZA 3IU9A 1MATA 1R5HA 4IU6A 4U6EA 1WL9A 2HOWA 2BHBA 2G6PA 1B59A 1WL6A 1R5GA 3MR1A 4IKSA 4OOKA 1C22A 1QXWA 2P9AA 3RVAA 3PKEA 5CDEA 4R60A 4FKCA 2BWTA 4HXXA 4U6CA 1PV9A 2GG8A 2Q92A 5CNXA 3D27A 3CB6A 1KP0A 4S2TP 4IKTA 4U6JA 3CB5A 3BIPA 1BOAA 2DFIA 4JUQA 2V3ZA 3FMQA 2MATA 5JFRA 1JAWA 2Q95A 1N51A 1W7VA 4FUKA 4IECA 1YVMA 2B3KA 4RZYA 4FLLA 2BHDA 4IKUA 2OAZA 5CLSA 4U76A 2V6CA 2BH3A 3L24A 2GG9A 4PV4A 1M35A 5CIKA 4RZZA 4B28A 2GU7A 1O0XA 5D6EA 1WN1A 2GU6A 3Q6DA 1YW8A 2NQ6A 2BWSA 3BITA 2ADUA 3MX6A 3PKDA 3TB5A 2EVOA 2V3YA 4RGZ1 4QR8A 1QXYA 1C27A 2EA4A 1C24A 5FCHA 4A6VA 5FCFA 3CTZA 2BN7A 3RORA 4Z7MA 1KQ9A
chains in the Genus database with same CATH topology
3S6BA 2OKNA 1C21A 3IU7A 2EVMA 5CDLA 4IF7A 4FLJA 4U75A 2BWWA 1XGMA 1KQ0A 1Y1NA 3TAVA 1XGOA 3BIQA 1XGNA 2ZSGA 4S01A 1YW7A 2GG0A 2GG5A 1B6AA 1QZYA 4FO8A 4U6ZA 3MATA 5CE6A 3FMRA 4ZWUA 3IU8A 4MATA 1R58A 2GGBA 2P99A 4PNCA 1C23A 4U73A 4FLIA 4U69A 2GGCA 4ZWPA 2B3HA 2GU4A 2NQ7A 3IG4A 3FM3A 2V3XA 1XGSA 4U71A 4EGEA 2BHCA 4U6WA 2GU5A 4IPAA 2BWXA 2GG3A 5E5BA 1BN5A 2BHAA 1YJ3A 4IDYA 1CHMA 4IKRA 4U1BA 2P98A 4KM3A 5CDVA 4U70A 2GTXA 4FLKA 5D6FA 2BWVA 2BWUA 1XNZA 3L7GA 1A16A 1W2MA 2IW2A 2Q96A 2Q93A 2EVCA 2GA2A 2GZ5A 2Q8KA 3PKAA 4A6WA 4S2RP 1WLRA 2Q94A 1WY2A 4ZWOA 2B3LA 3PKBA 5JHUA 5JI6A 2GG7A 2GG2A 2BB7A 3PKCA 2BWYA 4S00A 4ZNGA 2EA2A 1WKMA 4FO7A 1WBQA 1YW9A 1QXZA 3IU9A 1MATA 1R5HA 4IU6A 4U6EA 1WL9A 2HOWA 2BHBA 2G6PA 1B59A 1WL6A 1R5GA 3MR1A 4IKSA 4OOKA 1C22A 1QXWA 2P9AA 3RVAA 3PKEA 5CDEA 4R60A 4FKCA 2BWTA 4HXXA 4U6CA 1PV9A 2GG8A 2Q92A 5CNXA 3D27A 3CB6A 1KP0A 4S2TP 4IKTA 4U6JA 3CB5A 3BIPA 1BOAA 2DFIA 4JUQA 2V3ZA 3FMQA 2MATA 5JFRA 1JAWA 2Q95A 1N51A 1W7VA 4FUKA 4IECA 1YVMA 2B3KA 4RZYA 4FLLA 2BHDA 4IKUA 2OAZA 5CLSA 4U76A 2V6CA 2BH3A 3L24A 2GG9A 4PV4A 1M35A 5CIKA 4RZZA 4B28A 2GU7A 1O0XA 5D6EA 1WN1A 2GU6A 3Q6DA 1YW8A 2NQ6A 2BWSA 3BITA 2ADUA 3MX6A 3PKDA 3TB5A 2EVOA 2V3YA 4RGZ1 4QR8A 1QXYA 1C27A 2EA4A 1C24A 5FCHA 4A6VA 5FCFA 3CTZA 2BN7A 3RORA 4Z7MA 1KQ9A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3S6B A;  2OKN A;  1C21 A;  3IU7 A;  2EVM A;  5CDL A;  4IF7 A;  4FLJ A;  4U75 A;  2BWW A;  1XGM A;  1KQ0 A;  1Y1N A;  3TAV A;  1XGO A;  3BIQ A;  1XGN A;  2ZSG A;  4S01 A;  1YW7 A;  2GG0 A;  2GG5 A;  1B6A A;  1QZY A;  4FO8 A;  4U6Z A;  3MAT A;  5CE6 A;  3FMR A;  4ZWU A;  3IU8 A;  4MAT A;  1R58 A;  2GGB A;  2P99 A;  4PNC A;  1C23 A;  4U73 A;  4FLI A;  4U69 A;  2GGC A;  4ZWP A;  2B3H A;  2GU4 A;  2NQ7 A;  3IG4 A;  3FM3 A;  2V3X A;  1XGS A;  4U71 A;  4EGE A;  2BHC A;  4U6W A;  2GU5 A;  4IPA A;  2BWX A;  2GG3 A;  5E5B A;  1BN5 A;  2BHA A;  1YJ3 A;  4IDY A;  1CHM A;  4IKR A;  4U1B A;  2P98 A;  4KM3 A;  5CDV A;  4U70 A;  2GTX A;  4FLK A;  5D6F A;  2BWV A;  2BWU A;  1XNZ A;  3L7G A;  1A16 A;  1W2M A;  2IW2 A;  2Q96 A;  2Q93 A;  2EVC A;  2GA2 A;  2GZ5 A;  2Q8K A;  3PKA A;  4A6W A;  4S2R P;  1WLR A;  2Q94 A;  1WY2 A;  4ZWO A;  2B3L A;  3PKB A;  5JHU A;  5JI6 A;  2GG7 A;  2GG2 A;  2BB7 A;  3PKC A;  2BWY A;  4S00 A;  4ZNG A;  2EA2 A;  1WKM A;  4FO7 A;  1WBQ A;  1YW9 A;  1QXZ A;  3IU9 A;  1MAT A;  1R5H A;  4IU6 A;  4U6E A;  1WL9 A;  2HOW A;  2BHB A;  2G6P A;  1B59 A;  1WL6 A;  1R5G A;  3MR1 A;  4IKS A;  4OOK A;  1C22 A;  1QXW A;  2P9A A;  3RVA A;  3PKE A;  5CDE A;  4R60 A;  4FKC A;  2BWT A;  4HXX A;  4U6C A;  1PV9 A;  2GG8 A;  2Q92 A;  5CNX A;  3D27 A;  3CB6 A;  1KP0 A;  4S2T P;  4IKT A;  4U6J A;  3CB5 A;  3BIP A;  1BOA A;  2DFI A;  4JUQ A;  2V3Z A;  3FMQ A;  2MAT A;  5JFR A;  1JAW A;  2Q95 A;  1N51 A;  1W7V A;  4FUK A;  4IEC A;  1YVM A;  2B3K A;  4RZY A;  4FLL A;  2BHD A;  4IKU A;  2OAZ A;  5CLS A;  4U76 A;  2V6C A;  2BH3 A;  3L24 A;  2GG9 A;  4PV4 A;  1M35 A;  5CIK A;  4RZZ A;  4B28 A;  2GU7 A;  1O0X A;  5D6E A;  1WN1 A;  2GU6 A;  3Q6D A;  1YW8 A;  2NQ6 A;  2BWS A;  3BIT A;  2ADU A;  3MX6 A;  3PKD A;  3TB5 A;  2EVO A;  2V3Y A;  4RGZ 1;  4QR8 A;  1QXY A;  1C27 A;  2EA4 A;  1C24 A;  5FCH A;  4A6V A;  5FCF A;  3CTZ A;  2BN7 A;  3ROR A;  4Z7M A;  1KQ9 A; 
#chains in the Genus database with same CATH topology
 3S6B A;  2OKN A;  1C21 A;  3IU7 A;  2EVM A;  5CDL A;  4IF7 A;  4FLJ A;  4U75 A;  2BWW A;  1XGM A;  1KQ0 A;  1Y1N A;  3TAV A;  1XGO A;  3BIQ A;  1XGN A;  2ZSG A;  4S01 A;  1YW7 A;  2GG0 A;  2GG5 A;  1B6A A;  1QZY A;  4FO8 A;  4U6Z A;  3MAT A;  5CE6 A;  3FMR A;  4ZWU A;  3IU8 A;  4MAT A;  1R58 A;  2GGB A;  2P99 A;  4PNC A;  1C23 A;  4U73 A;  4FLI A;  4U69 A;  2GGC A;  4ZWP A;  2B3H A;  2GU4 A;  2NQ7 A;  3IG4 A;  3FM3 A;  2V3X A;  1XGS A;  4U71 A;  4EGE A;  2BHC A;  4U6W A;  2GU5 A;  4IPA A;  2BWX A;  2GG3 A;  5E5B A;  1BN5 A;  2BHA A;  1YJ3 A;  4IDY A;  1CHM A;  4IKR A;  4U1B A;  2P98 A;  4KM3 A;  5CDV A;  4U70 A;  2GTX A;  4FLK A;  5D6F A;  2BWV A;  2BWU A;  1XNZ A;  3L7G A;  1A16 A;  1W2M A;  2IW2 A;  2Q96 A;  2Q93 A;  2EVC A;  2GA2 A;  2GZ5 A;  2Q8K A;  3PKA A;  4A6W A;  4S2R P;  1WLR A;  2Q94 A;  1WY2 A;  4ZWO A;  2B3L A;  3PKB A;  5JHU A;  5JI6 A;  2GG7 A;  2GG2 A;  2BB7 A;  3PKC A;  2BWY A;  4S00 A;  4ZNG A;  2EA2 A;  1WKM A;  4FO7 A;  1WBQ A;  1YW9 A;  1QXZ A;  3IU9 A;  1MAT A;  1R5H A;  4IU6 A;  4U6E A;  1WL9 A;  2HOW A;  2BHB A;  2G6P A;  1B59 A;  1WL6 A;  1R5G A;  3MR1 A;  4IKS A;  4OOK A;  1C22 A;  1QXW A;  2P9A A;  3RVA A;  3PKE A;  5CDE A;  4R60 A;  4FKC A;  2BWT A;  4HXX A;  4U6C A;  1PV9 A;  2GG8 A;  2Q92 A;  5CNX A;  3D27 A;  3CB6 A;  1KP0 A;  4S2T P;  4IKT A;  4U6J A;  3CB5 A;  3BIP A;  1BOA A;  2DFI A;  4JUQ A;  2V3Z A;  3FMQ A;  2MAT A;  5JFR A;  1JAW A;  2Q95 A;  1N51 A;  1W7V A;  4FUK A;  4IEC A;  1YVM A;  2B3K A;  4RZY A;  4FLL A;  2BHD A;  4IKU A;  2OAZ A;  5CLS A;  4U76 A;  2V6C A;  2BH3 A;  3L24 A;  2GG9 A;  4PV4 A;  1M35 A;  5CIK A;  4RZZ A;  4B28 A;  2GU7 A;  1O0X A;  5D6E A;  1WN1 A;  2GU6 A;  3Q6D A;  1YW8 A;  2NQ6 A;  2BWS A;  3BIT A;  2ADU A;  3MX6 A;  3PKD A;  3TB5 A;  2EVO A;  2V3Y A;  4RGZ 1;  4QR8 A;  1QXY A;  1C27 A;  2EA4 A;  1C24 A;  5FCH A;  4A6V A;  5FCF A;  3CTZ A;  2BN7 A;  3ROR A;  4Z7M A;  1KQ9 A; 
#chains in the Genus database with same CATH homology
 3S6B A;  2OKN A;  1C21 A;  3IU7 A;  2EVM A;  5CDL A;  4IF7 A;  4FLJ A;  4U75 A;  2BWW A;  1XGM A;  1KQ0 A;  1Y1N A;  3TAV A;  1XGO A;  3BIQ A;  1XGN A;  2ZSG A;  4S01 A;  1YW7 A;  2GG0 A;  2GG5 A;  1B6A A;  1QZY A;  4FO8 A;  4U6Z A;  3MAT A;  5CE6 A;  3FMR A;  4ZWU A;  3IU8 A;  4MAT A;  1R58 A;  2GGB A;  2P99 A;  4PNC A;  1C23 A;  4U73 A;  4FLI A;  4U69 A;  2GGC A;  4ZWP A;  2B3H A;  2GU4 A;  2NQ7 A;  3IG4 A;  3FM3 A;  2V3X A;  1XGS A;  4U71 A;  4EGE A;  2BHC A;  4U6W A;  2GU5 A;  4IPA A;  2BWX A;  2GG3 A;  5E5B A;  1BN5 A;  2BHA A;  1YJ3 A;  4IDY A;  1CHM A;  4IKR A;  4U1B A;  2P98 A;  4KM3 A;  5CDV A;  4U70 A;  2GTX A;  4FLK A;  5D6F A;  2BWV A;  2BWU A;  1XNZ A;  3L7G A;  1A16 A;  1W2M A;  2IW2 A;  2Q96 A;  2Q93 A;  2EVC A;  2GA2 A;  2GZ5 A;  2Q8K A;  3PKA A;  4A6W A;  4S2R P;  1WLR A;  2Q94 A;  1WY2 A;  4ZWO A;  2B3L A;  3PKB A;  5JHU A;  5JI6 A;  2GG7 A;  2GG2 A;  2BB7 A;  3PKC A;  2BWY A;  4S00 A;  4ZNG A;  2EA2 A;  1WKM A;  4FO7 A;  1WBQ A;  1YW9 A;  1QXZ A;  3IU9 A;  1MAT A;  1R5H A;  4IU6 A;  4U6E A;  1WL9 A;  2HOW A;  2BHB A;  2G6P A;  1B59 A;  1WL6 A;  1R5G A;  3MR1 A;  4IKS A;  4OOK A;  1C22 A;  1QXW A;  2P9A A;  3RVA A;  3PKE A;  5CDE A;  4R60 A;  4FKC A;  2BWT A;  4HXX A;  4U6C A;  1PV9 A;  2GG8 A;  2Q92 A;  5CNX A;  3D27 A;  3CB6 A;  1KP0 A;  4S2T P;  4IKT A;  4U6J A;  3CB5 A;  3BIP A;  1BOA A;  2DFI A;  4JUQ A;  2V3Z A;  3FMQ A;  2MAT A;  5JFR A;  1JAW A;  2Q95 A;  1N51 A;  1W7V A;  4FUK A;  4IEC A;  1YVM A;  2B3K A;  4RZY A;  4FLL A;  2BHD A;  4IKU A;  2OAZ A;  5CLS A;  4U76 A;  2V6C A;  2BH3 A;  3L24 A;  2GG9 A;  4PV4 A;  1M35 A;  5CIK A;  4RZZ A;  4B28 A;  2GU7 A;  1O0X A;  5D6E A;  1WN1 A;  2GU6 A;  3Q6D A;  1YW8 A;  2NQ6 A;  2BWS A;  3BIT A;  2ADU A;  3MX6 A;  3PKD A;  3TB5 A;  2EVO A;  2V3Y A;  4RGZ 1;  4QR8 A;  1QXY A;  1C27 A;  2EA4 A;  1C24 A;  5FCH A;  4A6V A;  5FCF A;  3CTZ A;  2BN7 A;  3ROR A;  4Z7M A;  1KQ9 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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