5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Proline dipeptidase
publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
1R5HA 3IU7A 4U1BA 3PKAA 1A16A 1KP0A 4OOKA 5E5BA 5JFRA 1C23A 3IG4A 4R60A 1YW9A 2NQ6A 4Z7MA 1YW8A 4ZWPA 2V3ZA 2GA2A 4IKRA 2P98A 3BITA 2Q94A 4ZNGA 3PN9A 2Q95A 4IDYA 2BWYA 5CNXA 1MATA 2OKNA 5D6EA 2BWUA 3MATA 1R58A 3L24A 1C27A 1XGSA 2B3LA 2DFIA 3PKCA 4FLIA 2GGBA 3PKEA 4IF7A 4U75A 2BWVA 2V3YA 2GG0A 3IL0A 1W2MA 4U71A 4EGEA 2GG5A 3OVKA 2EA2A 2GG9A 3CTZA 4RGZ1 4S2TP 4B28A 4U6WA 2V6CA 3IU8A 1QXZA 2V3XA 3TB5A 4IKUA 3RORA 2BWWA 1QZYA 3CB6A 1YW7A 3TAVA 1B59A 1BOAA 2GU6A 3PKDA 3FM3A 4JUQA 1WLRA 2EVMA 1QXYA 2IW2A 2GTXA 2Q93A 4U70A 1XGNA 2P9AA 4QR8A 4KM3A 1WY2A 2ZSGA 2B3KA 3BIPA 2Q92A 1WL6A 4HXXA 3RVAA 1QXWA 4MATA 4RZZA 1C21A 4IKTA 1B6AA 2GU5A 1M35A 1R5GA 2ADUA 4FLKA 5FCFA 2BHBA 5FCHA 2GG8A 2BB7A 2GGCA 4IECA 1JAWA 1WL9A 1WN1A 3PEBA 2BHAA 2GU4A 1PV9A 3L7GA 2EA4A 2BH3A 2GG2A 4U6EA 3IU9A 2BN7A 1Y1NA 2BHCA 3I7MA 2EVCA 2BWSA 4U6JA 3FMQA 2GG3A 4U6CA 2G6PA 4ZWUA 4FLLA 2BWXA 2HOWA 4IKSA 5CIKA 1XGMA 4IU6A 4RZYA 4S01A 4S00A 3S6BA 1YVMA 1WKMA 4U73A 1W7VA 3MR1A 1N51A 4U69A 5CDLA 3BIQA 4FO7A 4ZWOA 2GG7A 1XNZA 1KQ0A 5CLSA 3FMRA 3MX6A 4U6ZA 5JHUA 4FUKA 1YJ3A 4S2RP 2B3HA 1BN5A 1KQ9A 2NQ7A 2Q8KA 1C22A 4U76A 1WBQA 1XGOA 2EVOA 2GU7A 4FLJA 4FKCA 5CE6A 4IPAA 1C24A 2GZ5A 3D27A 4A6VA 3PKBA 3OOOA 1O0XA 5CDEA 3O5VA 3Q6DA 2OAZA 2BHDA 4A6WA 2Q96A 2MATA 5E2CA 3QOCA 1CHMA 2P99A 5CDVA 4PV4A 2BWTA 4FO8A 4PNCA 5D6FA 5JI6A 3CB5A
chains in the Genus database with same CATH superfamily
1R5HA 3IU7A 4U1BA 3PKAA 1A16A 1KP0A 4OOKA 5E5BA 5JFRA 1C23A 3IG4A 4R60A 1YW9A 2NQ6A 4Z7MA 1YW8A 4ZWPA 2V3ZA 2GA2A 4IKRA 2P98A 3BITA 2Q94A 4ZNGA 3PN9A 2Q95A 4IDYA 2BWYA 5CNXA 1MATA 2OKNA 5D6EA 2BWUA 3MATA 1R58A 3L24A 1C27A 1XGSA 2B3LA 2DFIA 3PKCA 4FLIA 2GGBA 3PKEA 4IF7A 4U75A 2BWVA 2V3YA 2GG0A 3IL0A 1W2MA 4U71A 4EGEA 2GG5A 3OVKA 2EA2A 2GG9A 3CTZA 4RGZ1 4S2TP 4B28A 4U6WA 2V6CA 3IU8A 1QXZA 2V3XA 3TB5A 4IKUA 3RORA 2BWWA 1QZYA 3CB6A 1YW7A 3TAVA 1B59A 1BOAA 2GU6A 3PKDA 3FM3A 4JUQA 1WLRA 2EVMA 1QXYA 2IW2A 2GTXA 2Q93A 4U70A 1XGNA 2P9AA 4QR8A 4KM3A 1WY2A 2ZSGA 2B3KA 3BIPA 2Q92A 1WL6A 4HXXA 3RVAA 1QXWA 4MATA 4RZZA 1C21A 4IKTA 1B6AA 2GU5A 1M35A 1R5GA 2ADUA 4FLKA 5FCFA 2BHBA 5FCHA 2GG8A 2BB7A 2GGCA 4IECA 1JAWA 1WL9A 1WN1A 3PEBA 2BHAA 2GU4A 1PV9A 3L7GA 2EA4A 2BH3A 2GG2A 4U6EA 3IU9A 2BN7A 1Y1NA 2BHCA 3I7MA 2EVCA 2BWSA 4U6JA 3FMQA 2GG3A 4U6CA 2G6PA 4ZWUA 4FLLA 2BWXA 2HOWA 4IKSA 5CIKA 1XGMA 4IU6A 4RZYA 4S01A 4S00A 3S6BA 1YVMA 1WKMA 4U73A 1W7VA 3MR1A 1N51A 4U69A 5CDLA 3BIQA 4FO7A 4ZWOA 2GG7A 1XNZA 1KQ0A 5CLSA 3FMRA 3MX6A 4U6ZA 5JHUA 4FUKA 1YJ3A 4S2RP 2B3HA 1BN5A 1KQ9A 2NQ7A 2Q8KA 1C22A 4U76A 1WBQA 1XGOA 2EVOA 2GU7A 4FLJA 4FKCA 5CE6A 4IPAA 1C24A 2GZ5A 3D27A 4A6VA 3PKBA 3OOOA 1O0XA 5CDEA 3O5VA 3Q6DA 2OAZA 2BHDA 4A6WA 2Q96A 2MATA 5E2CA 3QOCA 1CHMA 2P99A 5CDVA 4PV4A 2BWTA 4FO8A 4PNCA 5D6FA 5JI6A 3CB5A
chains in the Genus database with same CATH topology
1R5HA 3IU7A 4U1BA 3PKAA 1A16A 1KP0A 4OOKA 5E5BA 5JFRA 1C23A 3IG4A 4R60A 1YW9A 2NQ6A 4Z7MA 1YW8A 4ZWPA 2V3ZA 2GA2A 4IKRA 2P98A 3BITA 2Q94A 4ZNGA 3PN9A 2Q95A 4IDYA 2BWYA 5CNXA 1MATA 2OKNA 5D6EA 2BWUA 3MATA 1R58A 3L24A 1C27A 1XGSA 2B3LA 2DFIA 3PKCA 4FLIA 2GGBA 3PKEA 4IF7A 4U75A 2BWVA 2V3YA 2GG0A 3IL0A 1W2MA 4U71A 4EGEA 2GG5A 3OVKA 2EA2A 2GG9A 3CTZA 4RGZ1 4S2TP 4B28A 4U6WA 2V6CA 3IU8A 1QXZA 2V3XA 3TB5A 4IKUA 3RORA 2BWWA 1QZYA 3CB6A 1YW7A 3TAVA 1B59A 1BOAA 2GU6A 3PKDA 3FM3A 4JUQA 1WLRA 2EVMA 1QXYA 2IW2A 2GTXA 2Q93A 4U70A 1XGNA 2P9AA 4QR8A 4KM3A 1WY2A 2ZSGA 2B3KA 3BIPA 2Q92A 1WL6A 4HXXA 3RVAA 1QXWA 4MATA 4RZZA 1C21A 4IKTA 1B6AA 2GU5A 1M35A 1R5GA 2ADUA 4FLKA 5FCFA 2BHBA 5FCHA 2GG8A 2BB7A 2GGCA 4IECA 1JAWA 1WL9A 1WN1A 3PEBA 2BHAA 2GU4A 1PV9A 3L7GA 2EA4A 2BH3A 2GG2A 4U6EA 3IU9A 2BN7A 1Y1NA 2BHCA 3I7MA 2EVCA 2BWSA 4U6JA 3FMQA 2GG3A 4U6CA 2G6PA 4ZWUA 4FLLA 2BWXA 2HOWA 4IKSA 5CIKA 1XGMA 4IU6A 4RZYA 4S01A 4S00A 3S6BA 1YVMA 1WKMA 4U73A 1W7VA 3MR1A 1N51A 4U69A 5CDLA 3BIQA 4FO7A 4ZWOA 2GG7A 1XNZA 1KQ0A 5CLSA 3FMRA 3MX6A 4U6ZA 5JHUA 4FUKA 1YJ3A 4S2RP 2B3HA 1BN5A 1KQ9A 2NQ7A 2Q8KA 1C22A 4U76A 1WBQA 1XGOA 2EVOA 2GU7A 4FLJA 4FKCA 5CE6A 4IPAA 1C24A 2GZ5A 3D27A 4A6VA 3PKBA 3OOOA 1O0XA 5CDEA 3O5VA 3Q6DA 2OAZA 2BHDA 4A6WA 2Q96A 2MATA 5E2CA 3QOCA 1CHMA 2P99A 5CDVA 4PV4A 2BWTA 4FO8A 4PNCA 5D6FA 5JI6A 3CB5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1R5H A;  3IU7 A;  4U1B A;  3PKA A;  1A16 A;  1KP0 A;  4OOK A;  5E5B A;  5JFR A;  1C23 A;  3IG4 A;  4R60 A;  1YW9 A;  2NQ6 A;  4Z7M A;  1YW8 A;  4ZWP A;  2V3Z A;  2GA2 A;  4IKR A;  2P98 A;  3BIT A;  2Q94 A;  4ZNG A;  3PN9 A;  2Q95 A;  4IDY A;  2BWY A;  5CNX A;  1MAT A;  2OKN A;  5D6E A;  2BWU A;  3MAT A;  1R58 A;  3L24 A;  1C27 A;  1XGS A;  2B3L A;  2DFI A;  3PKC A;  4FLI A;  2GGB A;  3PKE A;  4IF7 A;  4U75 A;  2BWV A;  2V3Y A;  2GG0 A;  3IL0 A;  1W2M A;  4U71 A;  4EGE A;  2GG5 A;  3OVK A;  2EA2 A;  2GG9 A;  3CTZ A;  4RGZ 1;  4S2T P;  4B28 A;  4U6W A;  2V6C A;  3IU8 A;  1QXZ A;  2V3X A;  3TB5 A;  4IKU A;  3ROR A;  2BWW A;  1QZY A;  3CB6 A;  1YW7 A;  3TAV A;  1B59 A;  1BOA A;  2GU6 A;  3PKD A;  3FM3 A;  4JUQ A;  1WLR A;  2EVM A;  1QXY A;  2IW2 A;  2GTX A;  2Q93 A;  4U70 A;  1XGN A;  2P9A A;  4QR8 A;  4KM3 A;  1WY2 A;  2ZSG A;  2B3K A;  3BIP A;  2Q92 A;  1WL6 A;  4HXX A;  3RVA A;  1QXW A;  4MAT A;  4RZZ A;  1C21 A;  4IKT A;  1B6A A;  2GU5 A;  1M35 A;  1R5G A;  2ADU A;  4FLK A;  5FCF A;  2BHB A;  5FCH A;  2GG8 A;  2BB7 A;  2GGC A;  4IEC A;  1JAW A;  1WL9 A;  1WN1 A;  3PEB A;  2BHA A;  2GU4 A;  1PV9 A;  3L7G A;  2EA4 A;  2BH3 A;  2GG2 A;  4U6E A;  3IU9 A;  2BN7 A;  1Y1N A;  2BHC A;  3I7M A;  2EVC A;  2BWS A;  4U6J A;  3FMQ A;  2GG3 A;  4U6C A;  2G6P A;  4ZWU A;  4FLL A;  2BWX A;  2HOW A;  4IKS A;  5CIK A;  1XGM A;  4IU6 A;  4RZY A;  4S01 A;  4S00 A;  3S6B A;  1YVM A;  1WKM A;  4U73 A;  1W7V A;  3MR1 A;  1N51 A;  4U69 A;  5CDL A;  3BIQ A;  4FO7 A;  4ZWO A;  2GG7 A;  1XNZ A;  1KQ0 A;  5CLS A;  3FMR A;  3MX6 A;  4U6Z A;  5JHU A;  4FUK A;  1YJ3 A;  4S2R P;  2B3H A;  1BN5 A;  1KQ9 A;  2NQ7 A;  2Q8K A;  1C22 A;  4U76 A;  1WBQ A;  1XGO A;  2EVO A;  2GU7 A;  4FLJ A;  4FKC A;  5CE6 A;  4IPA A;  1C24 A;  2GZ5 A;  3D27 A;  4A6V A;  3PKB A;  3OOO A;  1O0X A;  5CDE A;  3O5V A;  3Q6D A;  2OAZ A;  2BHD A;  4A6W A;  2Q96 A;  2MAT A;  5E2C A;  3QOC A;  1CHM A;  2P99 A;  5CDV A;  4PV4 A;  2BWT A;  4FO8 A;  4PNC A;  5D6F A;  5JI6 A;  3CB5 A; 
#chains in the Genus database with same CATH topology
 1R5H A;  3IU7 A;  4U1B A;  3PKA A;  1A16 A;  1KP0 A;  4OOK A;  5E5B A;  5JFR A;  1C23 A;  3IG4 A;  4R60 A;  1YW9 A;  2NQ6 A;  4Z7M A;  1YW8 A;  4ZWP A;  2V3Z A;  2GA2 A;  4IKR A;  2P98 A;  3BIT A;  2Q94 A;  4ZNG A;  3PN9 A;  2Q95 A;  4IDY A;  2BWY A;  5CNX A;  1MAT A;  2OKN A;  5D6E A;  2BWU A;  3MAT A;  1R58 A;  3L24 A;  1C27 A;  1XGS A;  2B3L A;  2DFI A;  3PKC A;  4FLI A;  2GGB A;  3PKE A;  4IF7 A;  4U75 A;  2BWV A;  2V3Y A;  2GG0 A;  3IL0 A;  1W2M A;  4U71 A;  4EGE A;  2GG5 A;  3OVK A;  2EA2 A;  2GG9 A;  3CTZ A;  4RGZ 1;  4S2T P;  4B28 A;  4U6W A;  2V6C A;  3IU8 A;  1QXZ A;  2V3X A;  3TB5 A;  4IKU A;  3ROR A;  2BWW A;  1QZY A;  3CB6 A;  1YW7 A;  3TAV A;  1B59 A;  1BOA A;  2GU6 A;  3PKD A;  3FM3 A;  4JUQ A;  1WLR A;  2EVM A;  1QXY A;  2IW2 A;  2GTX A;  2Q93 A;  4U70 A;  1XGN A;  2P9A A;  4QR8 A;  4KM3 A;  1WY2 A;  2ZSG A;  2B3K A;  3BIP A;  2Q92 A;  1WL6 A;  4HXX A;  3RVA A;  1QXW A;  4MAT A;  4RZZ A;  1C21 A;  4IKT A;  1B6A A;  2GU5 A;  1M35 A;  1R5G A;  2ADU A;  4FLK A;  5FCF A;  2BHB A;  5FCH A;  2GG8 A;  2BB7 A;  2GGC A;  4IEC A;  1JAW A;  1WL9 A;  1WN1 A;  3PEB A;  2BHA A;  2GU4 A;  1PV9 A;  3L7G A;  2EA4 A;  2BH3 A;  2GG2 A;  4U6E A;  3IU9 A;  2BN7 A;  1Y1N A;  2BHC A;  3I7M A;  2EVC A;  2BWS A;  4U6J A;  3FMQ A;  2GG3 A;  4U6C A;  2G6P A;  4ZWU A;  4FLL A;  2BWX A;  2HOW A;  4IKS A;  5CIK A;  1XGM A;  4IU6 A;  4RZY A;  4S01 A;  4S00 A;  3S6B A;  1YVM A;  1WKM A;  4U73 A;  1W7V A;  3MR1 A;  1N51 A;  4U69 A;  5CDL A;  3BIQ A;  4FO7 A;  4ZWO A;  2GG7 A;  1XNZ A;  1KQ0 A;  5CLS A;  3FMR A;  3MX6 A;  4U6Z A;  5JHU A;  4FUK A;  1YJ3 A;  4S2R P;  2B3H A;  1BN5 A;  1KQ9 A;  2NQ7 A;  2Q8K A;  1C22 A;  4U76 A;  1WBQ A;  1XGO A;  2EVO A;  2GU7 A;  4FLJ A;  4FKC A;  5CE6 A;  4IPA A;  1C24 A;  2GZ5 A;  3D27 A;  4A6V A;  3PKB A;  3OOO A;  1O0X A;  5CDE A;  3O5V A;  3Q6D A;  2OAZ A;  2BHD A;  4A6W A;  2Q96 A;  2MAT A;  5E2C A;  3QOC A;  1CHM A;  2P99 A;  5CDV A;  4PV4 A;  2BWT A;  4FO8 A;  4PNC A;  5D6F A;  5JI6 A;  3CB5 A; 
#chains in the Genus database with same CATH homology
 1R5H A;  3IU7 A;  4U1B A;  3PKA A;  1A16 A;  1KP0 A;  4OOK A;  5E5B A;  5JFR A;  1C23 A;  3IG4 A;  4R60 A;  1YW9 A;  2NQ6 A;  4Z7M A;  1YW8 A;  4ZWP A;  2V3Z A;  2GA2 A;  4IKR A;  2P98 A;  3BIT A;  2Q94 A;  4ZNG A;  3PN9 A;  2Q95 A;  4IDY A;  2BWY A;  5CNX A;  1MAT A;  2OKN A;  5D6E A;  2BWU A;  3MAT A;  1R58 A;  3L24 A;  1C27 A;  1XGS A;  2B3L A;  2DFI A;  3PKC A;  4FLI A;  2GGB A;  3PKE A;  4IF7 A;  4U75 A;  2BWV A;  2V3Y A;  2GG0 A;  3IL0 A;  1W2M A;  4U71 A;  4EGE A;  2GG5 A;  3OVK A;  2EA2 A;  2GG9 A;  3CTZ A;  4RGZ 1;  4S2T P;  4B28 A;  4U6W A;  2V6C A;  3IU8 A;  1QXZ A;  2V3X A;  3TB5 A;  4IKU A;  3ROR A;  2BWW A;  1QZY A;  3CB6 A;  1YW7 A;  3TAV A;  1B59 A;  1BOA A;  2GU6 A;  3PKD A;  3FM3 A;  4JUQ A;  1WLR A;  2EVM A;  1QXY A;  2IW2 A;  2GTX A;  2Q93 A;  4U70 A;  1XGN A;  2P9A A;  4QR8 A;  4KM3 A;  1WY2 A;  2ZSG A;  2B3K A;  3BIP A;  2Q92 A;  1WL6 A;  4HXX A;  3RVA A;  1QXW A;  4MAT A;  4RZZ A;  1C21 A;  4IKT A;  1B6A A;  2GU5 A;  1M35 A;  1R5G A;  2ADU A;  4FLK A;  5FCF A;  2BHB A;  5FCH A;  2GG8 A;  2BB7 A;  2GGC A;  4IEC A;  1JAW A;  1WL9 A;  1WN1 A;  3PEB A;  2BHA A;  2GU4 A;  1PV9 A;  3L7G A;  2EA4 A;  2BH3 A;  2GG2 A;  4U6E A;  3IU9 A;  2BN7 A;  1Y1N A;  2BHC A;  3I7M A;  2EVC A;  2BWS A;  4U6J A;  3FMQ A;  2GG3 A;  4U6C A;  2G6P A;  4ZWU A;  4FLL A;  2BWX A;  2HOW A;  4IKS A;  5CIK A;  1XGM A;  4IU6 A;  4RZY A;  4S01 A;  4S00 A;  3S6B A;  1YVM A;  1WKM A;  4U73 A;  1W7V A;  3MR1 A;  1N51 A;  4U69 A;  5CDL A;  3BIQ A;  4FO7 A;  4ZWO A;  2GG7 A;  1XNZ A;  1KQ0 A;  5CLS A;  3FMR A;  3MX6 A;  4U6Z A;  5JHU A;  4FUK A;  1YJ3 A;  4S2R P;  2B3H A;  1BN5 A;  1KQ9 A;  2NQ7 A;  2Q8K A;  1C22 A;  4U76 A;  1WBQ A;  1XGO A;  2EVO A;  2GU7 A;  4FLJ A;  4FKC A;  5CE6 A;  4IPA A;  1C24 A;  2GZ5 A;  3D27 A;  4A6V A;  3PKB A;  3OOO A;  1O0X A;  5CDE A;  3O5V A;  3Q6D A;  2OAZ A;  2BHD A;  4A6W A;  2Q96 A;  2MAT A;  5E2C A;  3QOC A;  1CHM A;  2P99 A;  5CDV A;  4PV4 A;  2BWT A;  4FO8 A;  4PNC A;  5D6F A;  5JI6 A;  3CB5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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