5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Proline dipeptidase
publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
4IKUA 4QR8A 2GZ5A 3PKDA 1B59A 2Q94A 1QXWA 1KQ0A 3D27A 1WN1A 3IL0A 4ZWPA 1WL9A 5CLSA 3FMQA 4HXXA 3CB6A 1WLRA 3OOOA 3PEBA 2GG8A 5JHUA 4IECA 1M35A 5E2CA 2DFIA 4EGEA 4R60A 3IU7A 2HOWA 4U6ZA 1YW9A 4RGZ1 2Q93A 4U73A 3RVAA 4B28A 2NQ7A 4IU6A 4U6JA 3TAVA 1C24A 4FLLA 2B3KA 1N51A 3CB5A 1W2MA 2NQ6A 4FO7A 4U1BA 3BITA 1WBQA 1XNZA 2EVCA 2BWTA 4IKRA 2OAZA 1XGOA 3IU8A 2BH3A 2GU7A 1BOAA 4S00A 5CIKA 2OKNA 1C21A 2GG2A 2GU4A 4PNCA 3IU9A 2V3YA 2V3XA 2BWXA 1MATA 4U70A 2Q8KA 4S01A 2BHCA 1C27A 2ADUA 4FLKA 4IKSA 3MATA 1CHMA 2P98A 5CE6A 4IF7A 1WKMA 2BHDA 3PKEA 1XGNA 3QOCA 4S2TP 2BWYA 2B3HA 2Q95A 4U6CA 4A6WA 4KM3A 3O5VA 1YVMA 1R5GA 3L24A 2GGCA 2Q92A 4MATA 4JUQA 2EVOA 3PKBA 1YJ3A 4FLJA 4FLIA 4Z7MA 2BHAA 4IKTA 4FKCA 2ZSGA 4A6VA 5CDVA 1XGSA 2Q96A 1YW7A 4S2RP 4FO8A 4U6WA 4U75A 3RORA 5JI6A 3TB5A 2P9AA 2GG3A 4U71A 5D6FA 1C22A 2BB7A 4ZWOA 1B6AA 3FM3A 1W7VA 2BHBA 2GG5A 1JAWA 5CDLA 2GU6A 3MX6A 4RZZA 3MR1A 2MATA 3BIPA 2GGBA 5FCFA 3L7GA 2V3ZA 5JFRA 2IW2A 4ZNGA 2GG0A 1A16A 2V6CA 3CTZA 3OVKA 3FMRA 1PV9A 3I7MA 2BWWA 1QXYA 1WY2A 1O0XA 2G6PA 2GU5A 4ZWUA 3PKAA 3PN9A 1R5HA 3BIQA 2BWSA 4U6EA 1XGMA 2BN7A 1KQ9A 1YW8A 4U69A 3Q6DA 5D6EA 1C23A 1KP0A 5CNXA 1R58A 3PKCA 2EA4A 2BWVA 3IG4A 2EVMA 5CDEA 2GTXA 4FUKA 1QZYA 4OOKA 1QXZA 2GG9A 4RZYA 2P99A 5E5BA 1WL6A 1Y1NA 2BWUA 2EA2A 4PV4A 5FCHA 4IPAA 2GG7A 2B3LA 1BN5A 2GA2A 3S6BA 4IDYA 4U76A
chains in the Genus database with same CATH superfamily
4IKUA 4QR8A 2GZ5A 3PKDA 1B59A 2Q94A 1QXWA 1KQ0A 3D27A 1WN1A 3IL0A 4ZWPA 1WL9A 5CLSA 3FMQA 4HXXA 3CB6A 1WLRA 3OOOA 3PEBA 2GG8A 5JHUA 4IECA 1M35A 5E2CA 2DFIA 4EGEA 4R60A 3IU7A 2HOWA 4U6ZA 1YW9A 4RGZ1 2Q93A 4U73A 3RVAA 4B28A 2NQ7A 4IU6A 4U6JA 3TAVA 1C24A 4FLLA 2B3KA 1N51A 3CB5A 1W2MA 2NQ6A 4FO7A 4U1BA 3BITA 1WBQA 1XNZA 2EVCA 2BWTA 4IKRA 2OAZA 1XGOA 3IU8A 2BH3A 2GU7A 1BOAA 4S00A 5CIKA 2OKNA 1C21A 2GG2A 2GU4A 4PNCA 3IU9A 2V3YA 2V3XA 2BWXA 1MATA 4U70A 2Q8KA 4S01A 2BHCA 1C27A 2ADUA 4FLKA 4IKSA 3MATA 1CHMA 2P98A 5CE6A 4IF7A 1WKMA 2BHDA 3PKEA 1XGNA 3QOCA 4S2TP 2BWYA 2B3HA 2Q95A 4U6CA 4A6WA 4KM3A 3O5VA 1YVMA 1R5GA 3L24A 2GGCA 2Q92A 4MATA 4JUQA 2EVOA 3PKBA 1YJ3A 4FLJA 4FLIA 4Z7MA 2BHAA 4IKTA 4FKCA 2ZSGA 4A6VA 5CDVA 1XGSA 2Q96A 1YW7A 4S2RP 4FO8A 4U6WA 4U75A 3RORA 5JI6A 3TB5A 2P9AA 2GG3A 4U71A 5D6FA 1C22A 2BB7A 4ZWOA 1B6AA 3FM3A 1W7VA 2BHBA 2GG5A 1JAWA 5CDLA 2GU6A 3MX6A 4RZZA 3MR1A 2MATA 3BIPA 2GGBA 5FCFA 3L7GA 2V3ZA 5JFRA 2IW2A 4ZNGA 2GG0A 1A16A 2V6CA 3CTZA 3OVKA 3FMRA 1PV9A 3I7MA 2BWWA 1QXYA 1WY2A 1O0XA 2G6PA 2GU5A 4ZWUA 3PKAA 3PN9A 1R5HA 3BIQA 2BWSA 4U6EA 1XGMA 2BN7A 1KQ9A 1YW8A 4U69A 3Q6DA 5D6EA 1C23A 1KP0A 5CNXA 1R58A 3PKCA 2EA4A 2BWVA 3IG4A 2EVMA 5CDEA 2GTXA 4FUKA 1QZYA 4OOKA 1QXZA 2GG9A 4RZYA 2P99A 5E5BA 1WL6A 1Y1NA 2BWUA 2EA2A 4PV4A 5FCHA 4IPAA 2GG7A 2B3LA 1BN5A 2GA2A 3S6BA 4IDYA 4U76A
chains in the Genus database with same CATH topology
4IKUA 4QR8A 2GZ5A 3PKDA 1B59A 2Q94A 1QXWA 1KQ0A 3D27A 1WN1A 3IL0A 4ZWPA 1WL9A 5CLSA 3FMQA 4HXXA 3CB6A 1WLRA 3OOOA 3PEBA 2GG8A 5JHUA 4IECA 1M35A 5E2CA 2DFIA 4EGEA 4R60A 3IU7A 2HOWA 4U6ZA 1YW9A 4RGZ1 2Q93A 4U73A 3RVAA 4B28A 2NQ7A 4IU6A 4U6JA 3TAVA 1C24A 4FLLA 2B3KA 1N51A 3CB5A 1W2MA 2NQ6A 4FO7A 4U1BA 3BITA 1WBQA 1XNZA 2EVCA 2BWTA 4IKRA 2OAZA 1XGOA 3IU8A 2BH3A 2GU7A 1BOAA 4S00A 5CIKA 2OKNA 1C21A 2GG2A 2GU4A 4PNCA 3IU9A 2V3YA 2V3XA 2BWXA 1MATA 4U70A 2Q8KA 4S01A 2BHCA 1C27A 2ADUA 4FLKA 4IKSA 3MATA 1CHMA 2P98A 5CE6A 4IF7A 1WKMA 2BHDA 3PKEA 1XGNA 3QOCA 4S2TP 2BWYA 2B3HA 2Q95A 4U6CA 4A6WA 4KM3A 3O5VA 1YVMA 1R5GA 3L24A 2GGCA 2Q92A 4MATA 4JUQA 2EVOA 3PKBA 1YJ3A 4FLJA 4FLIA 4Z7MA 2BHAA 4IKTA 4FKCA 2ZSGA 4A6VA 5CDVA 1XGSA 2Q96A 1YW7A 4S2RP 4FO8A 4U6WA 4U75A 3RORA 5JI6A 3TB5A 2P9AA 2GG3A 4U71A 5D6FA 1C22A 2BB7A 4ZWOA 1B6AA 3FM3A 1W7VA 2BHBA 2GG5A 1JAWA 5CDLA 2GU6A 3MX6A 4RZZA 3MR1A 2MATA 3BIPA 2GGBA 5FCFA 3L7GA 2V3ZA 5JFRA 2IW2A 4ZNGA 2GG0A 1A16A 2V6CA 3CTZA 3OVKA 3FMRA 1PV9A 3I7MA 2BWWA 1QXYA 1WY2A 1O0XA 2G6PA 2GU5A 4ZWUA 3PKAA 3PN9A 1R5HA 3BIQA 2BWSA 4U6EA 1XGMA 2BN7A 1KQ9A 1YW8A 4U69A 3Q6DA 5D6EA 1C23A 1KP0A 5CNXA 1R58A 3PKCA 2EA4A 2BWVA 3IG4A 2EVMA 5CDEA 2GTXA 4FUKA 1QZYA 4OOKA 1QXZA 2GG9A 4RZYA 2P99A 5E5BA 1WL6A 1Y1NA 2BWUA 2EA2A 4PV4A 5FCHA 4IPAA 2GG7A 2B3LA 1BN5A 2GA2A 3S6BA 4IDYA 4U76A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKU A;  4QR8 A;  2GZ5 A;  3PKD A;  1B59 A;  2Q94 A;  1QXW A;  1KQ0 A;  3D27 A;  1WN1 A;  3IL0 A;  4ZWP A;  1WL9 A;  5CLS A;  3FMQ A;  4HXX A;  3CB6 A;  1WLR A;  3OOO A;  3PEB A;  2GG8 A;  5JHU A;  4IEC A;  1M35 A;  5E2C A;  2DFI A;  4EGE A;  4R60 A;  3IU7 A;  2HOW A;  4U6Z A;  1YW9 A;  4RGZ 1;  2Q93 A;  4U73 A;  3RVA A;  4B28 A;  2NQ7 A;  4IU6 A;  4U6J A;  3TAV A;  1C24 A;  4FLL A;  2B3K A;  1N51 A;  3CB5 A;  1W2M A;  2NQ6 A;  4FO7 A;  4U1B A;  3BIT A;  1WBQ A;  1XNZ A;  2EVC A;  2BWT A;  4IKR A;  2OAZ A;  1XGO A;  3IU8 A;  2BH3 A;  2GU7 A;  1BOA A;  4S00 A;  5CIK A;  2OKN A;  1C21 A;  2GG2 A;  2GU4 A;  4PNC A;  3IU9 A;  2V3Y A;  2V3X A;  2BWX A;  1MAT A;  4U70 A;  2Q8K A;  4S01 A;  2BHC A;  1C27 A;  2ADU A;  4FLK A;  4IKS A;  3MAT A;  1CHM A;  2P98 A;  5CE6 A;  4IF7 A;  1WKM A;  2BHD A;  3PKE A;  1XGN A;  3QOC A;  4S2T P;  2BWY A;  2B3H A;  2Q95 A;  4U6C A;  4A6W A;  4KM3 A;  3O5V A;  1YVM A;  1R5G A;  3L24 A;  2GGC A;  2Q92 A;  4MAT A;  4JUQ A;  2EVO A;  3PKB A;  1YJ3 A;  4FLJ A;  4FLI A;  4Z7M A;  2BHA A;  4IKT A;  4FKC A;  2ZSG A;  4A6V A;  5CDV A;  1XGS A;  2Q96 A;  1YW7 A;  4S2R P;  4FO8 A;  4U6W A;  4U75 A;  3ROR A;  5JI6 A;  3TB5 A;  2P9A A;  2GG3 A;  4U71 A;  5D6F A;  1C22 A;  2BB7 A;  4ZWO A;  1B6A A;  3FM3 A;  1W7V A;  2BHB A;  2GG5 A;  1JAW A;  5CDL A;  2GU6 A;  3MX6 A;  4RZZ A;  3MR1 A;  2MAT A;  3BIP A;  2GGB A;  5FCF A;  3L7G A;  2V3Z A;  5JFR A;  2IW2 A;  4ZNG A;  2GG0 A;  1A16 A;  2V6C A;  3CTZ A;  3OVK A;  3FMR A;  1PV9 A;  3I7M A;  2BWW A;  1QXY A;  1WY2 A;  1O0X A;  2G6P A;  2GU5 A;  4ZWU A;  3PKA A;  3PN9 A;  1R5H A;  3BIQ A;  2BWS A;  4U6E A;  1XGM A;  2BN7 A;  1KQ9 A;  1YW8 A;  4U69 A;  3Q6D A;  5D6E A;  1C23 A;  1KP0 A;  5CNX A;  1R58 A;  3PKC A;  2EA4 A;  2BWV A;  3IG4 A;  2EVM A;  5CDE A;  2GTX A;  4FUK A;  1QZY A;  4OOK A;  1QXZ A;  2GG9 A;  4RZY A;  2P99 A;  5E5B A;  1WL6 A;  1Y1N A;  2BWU A;  2EA2 A;  4PV4 A;  5FCH A;  4IPA A;  2GG7 A;  2B3L A;  1BN5 A;  2GA2 A;  3S6B A;  4IDY A;  4U76 A; 
#chains in the Genus database with same CATH topology
 4IKU A;  4QR8 A;  2GZ5 A;  3PKD A;  1B59 A;  2Q94 A;  1QXW A;  1KQ0 A;  3D27 A;  1WN1 A;  3IL0 A;  4ZWP A;  1WL9 A;  5CLS A;  3FMQ A;  4HXX A;  3CB6 A;  1WLR A;  3OOO A;  3PEB A;  2GG8 A;  5JHU A;  4IEC A;  1M35 A;  5E2C A;  2DFI A;  4EGE A;  4R60 A;  3IU7 A;  2HOW A;  4U6Z A;  1YW9 A;  4RGZ 1;  2Q93 A;  4U73 A;  3RVA A;  4B28 A;  2NQ7 A;  4IU6 A;  4U6J A;  3TAV A;  1C24 A;  4FLL A;  2B3K A;  1N51 A;  3CB5 A;  1W2M A;  2NQ6 A;  4FO7 A;  4U1B A;  3BIT A;  1WBQ A;  1XNZ A;  2EVC A;  2BWT A;  4IKR A;  2OAZ A;  1XGO A;  3IU8 A;  2BH3 A;  2GU7 A;  1BOA A;  4S00 A;  5CIK A;  2OKN A;  1C21 A;  2GG2 A;  2GU4 A;  4PNC A;  3IU9 A;  2V3Y A;  2V3X A;  2BWX A;  1MAT A;  4U70 A;  2Q8K A;  4S01 A;  2BHC A;  1C27 A;  2ADU A;  4FLK A;  4IKS A;  3MAT A;  1CHM A;  2P98 A;  5CE6 A;  4IF7 A;  1WKM A;  2BHD A;  3PKE A;  1XGN A;  3QOC A;  4S2T P;  2BWY A;  2B3H A;  2Q95 A;  4U6C A;  4A6W A;  4KM3 A;  3O5V A;  1YVM A;  1R5G A;  3L24 A;  2GGC A;  2Q92 A;  4MAT A;  4JUQ A;  2EVO A;  3PKB A;  1YJ3 A;  4FLJ A;  4FLI A;  4Z7M A;  2BHA A;  4IKT A;  4FKC A;  2ZSG A;  4A6V A;  5CDV A;  1XGS A;  2Q96 A;  1YW7 A;  4S2R P;  4FO8 A;  4U6W A;  4U75 A;  3ROR A;  5JI6 A;  3TB5 A;  2P9A A;  2GG3 A;  4U71 A;  5D6F A;  1C22 A;  2BB7 A;  4ZWO A;  1B6A A;  3FM3 A;  1W7V A;  2BHB A;  2GG5 A;  1JAW A;  5CDL A;  2GU6 A;  3MX6 A;  4RZZ A;  3MR1 A;  2MAT A;  3BIP A;  2GGB A;  5FCF A;  3L7G A;  2V3Z A;  5JFR A;  2IW2 A;  4ZNG A;  2GG0 A;  1A16 A;  2V6C A;  3CTZ A;  3OVK A;  3FMR A;  1PV9 A;  3I7M A;  2BWW A;  1QXY A;  1WY2 A;  1O0X A;  2G6P A;  2GU5 A;  4ZWU A;  3PKA A;  3PN9 A;  1R5H A;  3BIQ A;  2BWS A;  4U6E A;  1XGM A;  2BN7 A;  1KQ9 A;  1YW8 A;  4U69 A;  3Q6D A;  5D6E A;  1C23 A;  1KP0 A;  5CNX A;  1R58 A;  3PKC A;  2EA4 A;  2BWV A;  3IG4 A;  2EVM A;  5CDE A;  2GTX A;  4FUK A;  1QZY A;  4OOK A;  1QXZ A;  2GG9 A;  4RZY A;  2P99 A;  5E5B A;  1WL6 A;  1Y1N A;  2BWU A;  2EA2 A;  4PV4 A;  5FCH A;  4IPA A;  2GG7 A;  2B3L A;  1BN5 A;  2GA2 A;  3S6B A;  4IDY A;  4U76 A; 
#chains in the Genus database with same CATH homology
 4IKU A;  4QR8 A;  2GZ5 A;  3PKD A;  1B59 A;  2Q94 A;  1QXW A;  1KQ0 A;  3D27 A;  1WN1 A;  3IL0 A;  4ZWP A;  1WL9 A;  5CLS A;  3FMQ A;  4HXX A;  3CB6 A;  1WLR A;  3OOO A;  3PEB A;  2GG8 A;  5JHU A;  4IEC A;  1M35 A;  5E2C A;  2DFI A;  4EGE A;  4R60 A;  3IU7 A;  2HOW A;  4U6Z A;  1YW9 A;  4RGZ 1;  2Q93 A;  4U73 A;  3RVA A;  4B28 A;  2NQ7 A;  4IU6 A;  4U6J A;  3TAV A;  1C24 A;  4FLL A;  2B3K A;  1N51 A;  3CB5 A;  1W2M A;  2NQ6 A;  4FO7 A;  4U1B A;  3BIT A;  1WBQ A;  1XNZ A;  2EVC A;  2BWT A;  4IKR A;  2OAZ A;  1XGO A;  3IU8 A;  2BH3 A;  2GU7 A;  1BOA A;  4S00 A;  5CIK A;  2OKN A;  1C21 A;  2GG2 A;  2GU4 A;  4PNC A;  3IU9 A;  2V3Y A;  2V3X A;  2BWX A;  1MAT A;  4U70 A;  2Q8K A;  4S01 A;  2BHC A;  1C27 A;  2ADU A;  4FLK A;  4IKS A;  3MAT A;  1CHM A;  2P98 A;  5CE6 A;  4IF7 A;  1WKM A;  2BHD A;  3PKE A;  1XGN A;  3QOC A;  4S2T P;  2BWY A;  2B3H A;  2Q95 A;  4U6C A;  4A6W A;  4KM3 A;  3O5V A;  1YVM A;  1R5G A;  3L24 A;  2GGC A;  2Q92 A;  4MAT A;  4JUQ A;  2EVO A;  3PKB A;  1YJ3 A;  4FLJ A;  4FLI A;  4Z7M A;  2BHA A;  4IKT A;  4FKC A;  2ZSG A;  4A6V A;  5CDV A;  1XGS A;  2Q96 A;  1YW7 A;  4S2R P;  4FO8 A;  4U6W A;  4U75 A;  3ROR A;  5JI6 A;  3TB5 A;  2P9A A;  2GG3 A;  4U71 A;  5D6F A;  1C22 A;  2BB7 A;  4ZWO A;  1B6A A;  3FM3 A;  1W7V A;  2BHB A;  2GG5 A;  1JAW A;  5CDL A;  2GU6 A;  3MX6 A;  4RZZ A;  3MR1 A;  2MAT A;  3BIP A;  2GGB A;  5FCF A;  3L7G A;  2V3Z A;  5JFR A;  2IW2 A;  4ZNG A;  2GG0 A;  1A16 A;  2V6C A;  3CTZ A;  3OVK A;  3FMR A;  1PV9 A;  3I7M A;  2BWW A;  1QXY A;  1WY2 A;  1O0X A;  2G6P A;  2GU5 A;  4ZWU A;  3PKA A;  3PN9 A;  1R5H A;  3BIQ A;  2BWS A;  4U6E A;  1XGM A;  2BN7 A;  1KQ9 A;  1YW8 A;  4U69 A;  3Q6D A;  5D6E A;  1C23 A;  1KP0 A;  5CNX A;  1R58 A;  3PKC A;  2EA4 A;  2BWV A;  3IG4 A;  2EVM A;  5CDE A;  2GTX A;  4FUK A;  1QZY A;  4OOK A;  1QXZ A;  2GG9 A;  4RZY A;  2P99 A;  5E5B A;  1WL6 A;  1Y1N A;  2BWU A;  2EA2 A;  4PV4 A;  5FCH A;  4IPA A;  2GG7 A;  2B3L A;  1BN5 A;  2GA2 A;  3S6B A;  4IDY A;  4U76 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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