5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Proline dipeptidase
publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
4ZNGA 1WN1A 5D6FA 1XNZA 2GG2A 3RVAA 1QXZA 5CLSA 4U6WA 3TB5A 5CIKA 2HOWA 2BWVA 4FO7A 2GG0A 4ZWPA 2OAZA 2V6CA 3BITA 3L24A 2EA2A 2EVOA 4IKRA 1QZYA 2P98A 3O5VA 2GU4A 1XGOA 1XGMA 1XGSA 2GZ5A 4HXXA 2Q8KA 3PKAA 3PEBA 2BWXA 2GU5A 2GG7A 4IECA 5D6EA 2NQ7A 2Q95A 3PKBA 2ZSGA 4B28A 1W2MA 4R60A 1B6AA 2MATA 4U73A 4FLIA 1Y1NA 3QOCA 4FLKA 3MR1A 4U76A 2V3YA 2GU7A 1KP0A 1BOAA 2B3KA 5FCHA 2EA4A 2GG3A 1CHMA 1PV9A 4ZWUA 4U6EA 2V3ZA 5CDLA 3BIPA 2GG9A 2NQ6A 1WLRA 3OVKA 4A6WA 4Z7MA 2EVMA 2V3XA 2Q92A 4FLJA 1WL9A 4S2RP 5CE6A 1C27A 1WKMA 1YW8A 2P9AA 3FMRA 3IU8A 3CB5A 4JUQA 4IKUA 1N51A 3CB6A 4RZYA 1C24A 1BN5A 2Q93A 4KM3A 5CDEA 1WBQA 3MATA 1WL6A 5JI6A 2EVCA 4RGZ1 1YW7A 4U71A 3CTZA 4PV4A 4S01A 4IPAA 3PN9A 1C21A 2GG8A 1B59A 4ZWOA 1QXYA 3IU9A 4S00A 5CDVA 3OOOA 2GA2A 2BH3A 4FUKA 4U6ZA 3D27A 1KQ9A 1C23A 4IDYA 1WY2A 5CNXA 4IKSA 3L7GA 1W7VA 2BWTA 4U6CA 4IF7A 2BHAA 1YJ3A 3FM3A 3TAVA 4U6JA 4U75A 5JHUA 3RORA 2BWUA 4FKCA 2BWYA 4IKTA 4OOKA 5JFRA 3S6BA 3I7MA 2ADUA 2GU6A 2BHDA 3FMQA 2Q94A 2B3LA 1XGNA 1MATA 1R58A 2B3HA 3PKDA 2BWWA 4U70A 2BWSA 2GTXA 4FO8A 4PNCA 1M35A 1JAWA 1C22A 4IU6A 4MATA 3IU7A 3IG4A 3Q6DA 1R5HA 2G6PA 2BHCA 1YW9A 1A16A 2IW2A 4EGEA 5E2CA 4QR8A 5E5BA 4A6VA 2BB7A 5FCFA 1QXWA 3PKEA 3IL0A 1KQ0A 1O0XA 2BHBA 3PKCA 2GG5A 1YVMA 4S2TP 4U1BA 2DFIA 4FLLA 2GGBA 2OKNA 3BIQA 2GGCA 2Q96A 4RZZA 1R5GA 4U69A 2P99A 3MX6A 2BN7A
chains in the Genus database with same CATH superfamily
4ZNGA 1WN1A 5D6FA 1XNZA 2GG2A 3RVAA 1QXZA 5CLSA 4U6WA 3TB5A 5CIKA 2HOWA 2BWVA 4FO7A 2GG0A 4ZWPA 2OAZA 2V6CA 3BITA 3L24A 2EA2A 2EVOA 4IKRA 1QZYA 2P98A 3O5VA 2GU4A 1XGOA 1XGMA 1XGSA 2GZ5A 4HXXA 2Q8KA 3PKAA 3PEBA 2BWXA 2GU5A 2GG7A 4IECA 5D6EA 2NQ7A 2Q95A 3PKBA 2ZSGA 4B28A 1W2MA 4R60A 1B6AA 2MATA 4U73A 4FLIA 1Y1NA 3QOCA 4FLKA 3MR1A 4U76A 2V3YA 2GU7A 1KP0A 1BOAA 2B3KA 5FCHA 2EA4A 2GG3A 1CHMA 1PV9A 4ZWUA 4U6EA 2V3ZA 5CDLA 3BIPA 2GG9A 2NQ6A 1WLRA 3OVKA 4A6WA 4Z7MA 2EVMA 2V3XA 2Q92A 4FLJA 1WL9A 4S2RP 5CE6A 1C27A 1WKMA 1YW8A 2P9AA 3FMRA 3IU8A 3CB5A 4JUQA 4IKUA 1N51A 3CB6A 4RZYA 1C24A 1BN5A 2Q93A 4KM3A 5CDEA 1WBQA 3MATA 1WL6A 5JI6A 2EVCA 4RGZ1 1YW7A 4U71A 3CTZA 4PV4A 4S01A 4IPAA 3PN9A 1C21A 2GG8A 1B59A 4ZWOA 1QXYA 3IU9A 4S00A 5CDVA 3OOOA 2GA2A 2BH3A 4FUKA 4U6ZA 3D27A 1KQ9A 1C23A 4IDYA 1WY2A 5CNXA 4IKSA 3L7GA 1W7VA 2BWTA 4U6CA 4IF7A 2BHAA 1YJ3A 3FM3A 3TAVA 4U6JA 4U75A 5JHUA 3RORA 2BWUA 4FKCA 2BWYA 4IKTA 4OOKA 5JFRA 3S6BA 3I7MA 2ADUA 2GU6A 2BHDA 3FMQA 2Q94A 2B3LA 1XGNA 1MATA 1R58A 2B3HA 3PKDA 2BWWA 4U70A 2BWSA 2GTXA 4FO8A 4PNCA 1M35A 1JAWA 1C22A 4IU6A 4MATA 3IU7A 3IG4A 3Q6DA 1R5HA 2G6PA 2BHCA 1YW9A 1A16A 2IW2A 4EGEA 5E2CA 4QR8A 5E5BA 4A6VA 2BB7A 5FCFA 1QXWA 3PKEA 3IL0A 1KQ0A 1O0XA 2BHBA 3PKCA 2GG5A 1YVMA 4S2TP 4U1BA 2DFIA 4FLLA 2GGBA 2OKNA 3BIQA 2GGCA 2Q96A 4RZZA 1R5GA 4U69A 2P99A 3MX6A 2BN7A
chains in the Genus database with same CATH topology
4ZNGA 1WN1A 5D6FA 1XNZA 2GG2A 3RVAA 1QXZA 5CLSA 4U6WA 3TB5A 5CIKA 2HOWA 2BWVA 4FO7A 2GG0A 4ZWPA 2OAZA 2V6CA 3BITA 3L24A 2EA2A 2EVOA 4IKRA 1QZYA 2P98A 3O5VA 2GU4A 1XGOA 1XGMA 1XGSA 2GZ5A 4HXXA 2Q8KA 3PKAA 3PEBA 2BWXA 2GU5A 2GG7A 4IECA 5D6EA 2NQ7A 2Q95A 3PKBA 2ZSGA 4B28A 1W2MA 4R60A 1B6AA 2MATA 4U73A 4FLIA 1Y1NA 3QOCA 4FLKA 3MR1A 4U76A 2V3YA 2GU7A 1KP0A 1BOAA 2B3KA 5FCHA 2EA4A 2GG3A 1CHMA 1PV9A 4ZWUA 4U6EA 2V3ZA 5CDLA 3BIPA 2GG9A 2NQ6A 1WLRA 3OVKA 4A6WA 4Z7MA 2EVMA 2V3XA 2Q92A 4FLJA 1WL9A 4S2RP 5CE6A 1C27A 1WKMA 1YW8A 2P9AA 3FMRA 3IU8A 3CB5A 4JUQA 4IKUA 1N51A 3CB6A 4RZYA 1C24A 1BN5A 2Q93A 4KM3A 5CDEA 1WBQA 3MATA 1WL6A 5JI6A 2EVCA 4RGZ1 1YW7A 4U71A 3CTZA 4PV4A 4S01A 4IPAA 3PN9A 1C21A 2GG8A 1B59A 4ZWOA 1QXYA 3IU9A 4S00A 5CDVA 3OOOA 2GA2A 2BH3A 4FUKA 4U6ZA 3D27A 1KQ9A 1C23A 4IDYA 1WY2A 5CNXA 4IKSA 3L7GA 1W7VA 2BWTA 4U6CA 4IF7A 2BHAA 1YJ3A 3FM3A 3TAVA 4U6JA 4U75A 5JHUA 3RORA 2BWUA 4FKCA 2BWYA 4IKTA 4OOKA 5JFRA 3S6BA 3I7MA 2ADUA 2GU6A 2BHDA 3FMQA 2Q94A 2B3LA 1XGNA 1MATA 1R58A 2B3HA 3PKDA 2BWWA 4U70A 2BWSA 2GTXA 4FO8A 4PNCA 1M35A 1JAWA 1C22A 4IU6A 4MATA 3IU7A 3IG4A 3Q6DA 1R5HA 2G6PA 2BHCA 1YW9A 1A16A 2IW2A 4EGEA 5E2CA 4QR8A 5E5BA 4A6VA 2BB7A 5FCFA 1QXWA 3PKEA 3IL0A 1KQ0A 1O0XA 2BHBA 3PKCA 2GG5A 1YVMA 4S2TP 4U1BA 2DFIA 4FLLA 2GGBA 2OKNA 3BIQA 2GGCA 2Q96A 4RZZA 1R5GA 4U69A 2P99A 3MX6A 2BN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4ZNG A;  1WN1 A;  5D6F A;  1XNZ A;  2GG2 A;  3RVA A;  1QXZ A;  5CLS A;  4U6W A;  3TB5 A;  5CIK A;  2HOW A;  2BWV A;  4FO7 A;  2GG0 A;  4ZWP A;  2OAZ A;  2V6C A;  3BIT A;  3L24 A;  2EA2 A;  2EVO A;  4IKR A;  1QZY A;  2P98 A;  3O5V A;  2GU4 A;  1XGO A;  1XGM A;  1XGS A;  2GZ5 A;  4HXX A;  2Q8K A;  3PKA A;  3PEB A;  2BWX A;  2GU5 A;  2GG7 A;  4IEC A;  5D6E A;  2NQ7 A;  2Q95 A;  3PKB A;  2ZSG A;  4B28 A;  1W2M A;  4R60 A;  1B6A A;  2MAT A;  4U73 A;  4FLI A;  1Y1N A;  3QOC A;  4FLK A;  3MR1 A;  4U76 A;  2V3Y A;  2GU7 A;  1KP0 A;  1BOA A;  2B3K A;  5FCH A;  2EA4 A;  2GG3 A;  1CHM A;  1PV9 A;  4ZWU A;  4U6E A;  2V3Z A;  5CDL A;  3BIP A;  2GG9 A;  2NQ6 A;  1WLR A;  3OVK A;  4A6W A;  4Z7M A;  2EVM A;  2V3X A;  2Q92 A;  4FLJ A;  1WL9 A;  4S2R P;  5CE6 A;  1C27 A;  1WKM A;  1YW8 A;  2P9A A;  3FMR A;  3IU8 A;  3CB5 A;  4JUQ A;  4IKU A;  1N51 A;  3CB6 A;  4RZY A;  1C24 A;  1BN5 A;  2Q93 A;  4KM3 A;  5CDE A;  1WBQ A;  3MAT A;  1WL6 A;  5JI6 A;  2EVC A;  4RGZ 1;  1YW7 A;  4U71 A;  3CTZ A;  4PV4 A;  4S01 A;  4IPA A;  3PN9 A;  1C21 A;  2GG8 A;  1B59 A;  4ZWO A;  1QXY A;  3IU9 A;  4S00 A;  5CDV A;  3OOO A;  2GA2 A;  2BH3 A;  4FUK A;  4U6Z A;  3D27 A;  1KQ9 A;  1C23 A;  4IDY A;  1WY2 A;  5CNX A;  4IKS A;  3L7G A;  1W7V A;  2BWT A;  4U6C A;  4IF7 A;  2BHA A;  1YJ3 A;  3FM3 A;  3TAV A;  4U6J A;  4U75 A;  5JHU A;  3ROR A;  2BWU A;  4FKC A;  2BWY A;  4IKT A;  4OOK A;  5JFR A;  3S6B A;  3I7M A;  2ADU A;  2GU6 A;  2BHD A;  3FMQ A;  2Q94 A;  2B3L A;  1XGN A;  1MAT A;  1R58 A;  2B3H A;  3PKD A;  2BWW A;  4U70 A;  2BWS A;  2GTX A;  4FO8 A;  4PNC A;  1M35 A;  1JAW A;  1C22 A;  4IU6 A;  4MAT A;  3IU7 A;  3IG4 A;  3Q6D A;  1R5H A;  2G6P A;  2BHC A;  1YW9 A;  1A16 A;  2IW2 A;  4EGE A;  5E2C A;  4QR8 A;  5E5B A;  4A6V A;  2BB7 A;  5FCF A;  1QXW A;  3PKE A;  3IL0 A;  1KQ0 A;  1O0X A;  2BHB A;  3PKC A;  2GG5 A;  1YVM A;  4S2T P;  4U1B A;  2DFI A;  4FLL A;  2GGB A;  2OKN A;  3BIQ A;  2GGC A;  2Q96 A;  4RZZ A;  1R5G A;  4U69 A;  2P99 A;  3MX6 A;  2BN7 A; 
#chains in the Genus database with same CATH topology
 4ZNG A;  1WN1 A;  5D6F A;  1XNZ A;  2GG2 A;  3RVA A;  1QXZ A;  5CLS A;  4U6W A;  3TB5 A;  5CIK A;  2HOW A;  2BWV A;  4FO7 A;  2GG0 A;  4ZWP A;  2OAZ A;  2V6C A;  3BIT A;  3L24 A;  2EA2 A;  2EVO A;  4IKR A;  1QZY A;  2P98 A;  3O5V A;  2GU4 A;  1XGO A;  1XGM A;  1XGS A;  2GZ5 A;  4HXX A;  2Q8K A;  3PKA A;  3PEB A;  2BWX A;  2GU5 A;  2GG7 A;  4IEC A;  5D6E A;  2NQ7 A;  2Q95 A;  3PKB A;  2ZSG A;  4B28 A;  1W2M A;  4R60 A;  1B6A A;  2MAT A;  4U73 A;  4FLI A;  1Y1N A;  3QOC A;  4FLK A;  3MR1 A;  4U76 A;  2V3Y A;  2GU7 A;  1KP0 A;  1BOA A;  2B3K A;  5FCH A;  2EA4 A;  2GG3 A;  1CHM A;  1PV9 A;  4ZWU A;  4U6E A;  2V3Z A;  5CDL A;  3BIP A;  2GG9 A;  2NQ6 A;  1WLR A;  3OVK A;  4A6W A;  4Z7M A;  2EVM A;  2V3X A;  2Q92 A;  4FLJ A;  1WL9 A;  4S2R P;  5CE6 A;  1C27 A;  1WKM A;  1YW8 A;  2P9A A;  3FMR A;  3IU8 A;  3CB5 A;  4JUQ A;  4IKU A;  1N51 A;  3CB6 A;  4RZY A;  1C24 A;  1BN5 A;  2Q93 A;  4KM3 A;  5CDE A;  1WBQ A;  3MAT A;  1WL6 A;  5JI6 A;  2EVC A;  4RGZ 1;  1YW7 A;  4U71 A;  3CTZ A;  4PV4 A;  4S01 A;  4IPA A;  3PN9 A;  1C21 A;  2GG8 A;  1B59 A;  4ZWO A;  1QXY A;  3IU9 A;  4S00 A;  5CDV A;  3OOO A;  2GA2 A;  2BH3 A;  4FUK A;  4U6Z A;  3D27 A;  1KQ9 A;  1C23 A;  4IDY A;  1WY2 A;  5CNX A;  4IKS A;  3L7G A;  1W7V A;  2BWT A;  4U6C A;  4IF7 A;  2BHA A;  1YJ3 A;  3FM3 A;  3TAV A;  4U6J A;  4U75 A;  5JHU A;  3ROR A;  2BWU A;  4FKC A;  2BWY A;  4IKT A;  4OOK A;  5JFR A;  3S6B A;  3I7M A;  2ADU A;  2GU6 A;  2BHD A;  3FMQ A;  2Q94 A;  2B3L A;  1XGN A;  1MAT A;  1R58 A;  2B3H A;  3PKD A;  2BWW A;  4U70 A;  2BWS A;  2GTX A;  4FO8 A;  4PNC A;  1M35 A;  1JAW A;  1C22 A;  4IU6 A;  4MAT A;  3IU7 A;  3IG4 A;  3Q6D A;  1R5H A;  2G6P A;  2BHC A;  1YW9 A;  1A16 A;  2IW2 A;  4EGE A;  5E2C A;  4QR8 A;  5E5B A;  4A6V A;  2BB7 A;  5FCF A;  1QXW A;  3PKE A;  3IL0 A;  1KQ0 A;  1O0X A;  2BHB A;  3PKC A;  2GG5 A;  1YVM A;  4S2T P;  4U1B A;  2DFI A;  4FLL A;  2GGB A;  2OKN A;  3BIQ A;  2GGC A;  2Q96 A;  4RZZ A;  1R5G A;  4U69 A;  2P99 A;  3MX6 A;  2BN7 A; 
#chains in the Genus database with same CATH homology
 4ZNG A;  1WN1 A;  5D6F A;  1XNZ A;  2GG2 A;  3RVA A;  1QXZ A;  5CLS A;  4U6W A;  3TB5 A;  5CIK A;  2HOW A;  2BWV A;  4FO7 A;  2GG0 A;  4ZWP A;  2OAZ A;  2V6C A;  3BIT A;  3L24 A;  2EA2 A;  2EVO A;  4IKR A;  1QZY A;  2P98 A;  3O5V A;  2GU4 A;  1XGO A;  1XGM A;  1XGS A;  2GZ5 A;  4HXX A;  2Q8K A;  3PKA A;  3PEB A;  2BWX A;  2GU5 A;  2GG7 A;  4IEC A;  5D6E A;  2NQ7 A;  2Q95 A;  3PKB A;  2ZSG A;  4B28 A;  1W2M A;  4R60 A;  1B6A A;  2MAT A;  4U73 A;  4FLI A;  1Y1N A;  3QOC A;  4FLK A;  3MR1 A;  4U76 A;  2V3Y A;  2GU7 A;  1KP0 A;  1BOA A;  2B3K A;  5FCH A;  2EA4 A;  2GG3 A;  1CHM A;  1PV9 A;  4ZWU A;  4U6E A;  2V3Z A;  5CDL A;  3BIP A;  2GG9 A;  2NQ6 A;  1WLR A;  3OVK A;  4A6W A;  4Z7M A;  2EVM A;  2V3X A;  2Q92 A;  4FLJ A;  1WL9 A;  4S2R P;  5CE6 A;  1C27 A;  1WKM A;  1YW8 A;  2P9A A;  3FMR A;  3IU8 A;  3CB5 A;  4JUQ A;  4IKU A;  1N51 A;  3CB6 A;  4RZY A;  1C24 A;  1BN5 A;  2Q93 A;  4KM3 A;  5CDE A;  1WBQ A;  3MAT A;  1WL6 A;  5JI6 A;  2EVC A;  4RGZ 1;  1YW7 A;  4U71 A;  3CTZ A;  4PV4 A;  4S01 A;  4IPA A;  3PN9 A;  1C21 A;  2GG8 A;  1B59 A;  4ZWO A;  1QXY A;  3IU9 A;  4S00 A;  5CDV A;  3OOO A;  2GA2 A;  2BH3 A;  4FUK A;  4U6Z A;  3D27 A;  1KQ9 A;  1C23 A;  4IDY A;  1WY2 A;  5CNX A;  4IKS A;  3L7G A;  1W7V A;  2BWT A;  4U6C A;  4IF7 A;  2BHA A;  1YJ3 A;  3FM3 A;  3TAV A;  4U6J A;  4U75 A;  5JHU A;  3ROR A;  2BWU A;  4FKC A;  2BWY A;  4IKT A;  4OOK A;  5JFR A;  3S6B A;  3I7M A;  2ADU A;  2GU6 A;  2BHD A;  3FMQ A;  2Q94 A;  2B3L A;  1XGN A;  1MAT A;  1R58 A;  2B3H A;  3PKD A;  2BWW A;  4U70 A;  2BWS A;  2GTX A;  4FO8 A;  4PNC A;  1M35 A;  1JAW A;  1C22 A;  4IU6 A;  4MAT A;  3IU7 A;  3IG4 A;  3Q6D A;  1R5H A;  2G6P A;  2BHC A;  1YW9 A;  1A16 A;  2IW2 A;  4EGE A;  5E2C A;  4QR8 A;  5E5B A;  4A6V A;  2BB7 A;  5FCF A;  1QXW A;  3PKE A;  3IL0 A;  1KQ0 A;  1O0X A;  2BHB A;  3PKC A;  2GG5 A;  1YVM A;  4S2T P;  4U1B A;  2DFI A;  4FLL A;  2GGB A;  2OKN A;  3BIQ A;  2GGC A;  2Q96 A;  4RZZ A;  1R5G A;  4U69 A;  2P99 A;  3MX6 A;  2BN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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