5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
1BOAA 1W7VA 4U6EA 4PNCA 3IU9A 2BHCA 2EVCA 3BIQA 5CLSA 2P9AA 4U75A 2EA2A 1R58A 4A6WA 4IKUA 4FLKA 2P98A 1WL9A 3O5VA 4FO8A 5CNXA 1C24A 4U6CA 5D6EA 3I7MA 5D6FA 4U1BA 4S2RP 2BHAA 3IL0A 3PEBA 5CE6A 3PKCA 4IECA 4KM3A 3PKDA 5CDEA 3PN9A 2G6PA 3L24A 2GU4A 4FLJA 3CB6A 1YW7A 2V3XA 2GU6A 3Q6DA 4B28A 4ZNGA 2GU5A 1N51A 1XNZA 1W2MA 2B3KA 2BWUA 4QR8A 4RZYA 3RVAA 4U70A 1WN1A 2BWYA 1R5GA 2BWTA 2Q93A 4U76A 1KQ0A 2MATA 4ZWUA 2GG9A 2Q94A 4MATA 4S01A 5FCHA 1QZYA 1WY2A 2Q96A 1QXZA 5CIKA 3PKEA 1WBQA 1C21A 1WL6A 2GG8A 2OKNA 2IW2A 3PKBA 1KQ9A 4IKTA 5JHUA 3MX6A 2GTXA 4IU6A 2ADUA 5JFRA 4RGZ1 2EVMA 3QOCA 2GGBA 2GG7A 4OOKA 1XGNA 2GGCA 4U6ZA 3IG4A 2OAZA 1C22A 3FM3A 4HXXA 2B3HA 1MATA 1M35A 2V6CA 3MATA 3PKAA 4IKSA 2EA4A 1A16A 2BWSA 4IF7A 4U6JA 1YW9A 2NQ7A 1XGOA 2NQ6A 2GG2A 2BHBA 1CHMA 4ZWPA 3CB5A 3S6BA 2BH3A 5JI6A 2GG0A 5FCFA 2EVOA 4A6VA 2GZ5A 2P99A 3RORA 5E5BA 1Y1NA 1WKMA 4U6WA 4FLLA 1XGMA 2BWVA 4FO7A 2HOWA 1O0XA 4FUKA 1WLRA 5CDLA 1YJ3A 4IDYA 1QXWA 3BITA 2GU7A 2Q8KA 4FKCA 4ZWOA 3FMQA 4EGEA 2BWXA 2BN7A 4U71A 4IKRA 2ZSGA 1R5HA 4U69A 1XGSA 3IU7A 3BIPA 1JAWA 2GG3A 1YVMA 2GA2A 1C27A 2DFIA 3MR1A 4U73A 1PV9A 4S2TP 2V3YA 2BWWA 3CTZA 5E2CA 2BB7A 2GG5A 5CDVA 1QXYA 2Q92A 4R60A 1B59A 4FLIA 2V3ZA 1BN5A 3IU8A 1KP0A 4S00A 1B6AA 4RZZA 3TAVA 2Q95A 3L7GA 2BHDA 3OVKA 1YW8A 2B3LA 1C23A 4PV4A 3TB5A 4JUQA 3D27A 4Z7MA 3FMRA 4IPAA 3OOOA
chains in the Genus database with same CATH superfamily
1BOAA 1W7VA 4U6EA 4PNCA 3IU9A 2BHCA 2EVCA 3BIQA 5CLSA 2P9AA 4U75A 2EA2A 1R58A 4A6WA 4IKUA 4FLKA 2P98A 1WL9A 3O5VA 4FO8A 5CNXA 1C24A 4U6CA 5D6EA 3I7MA 5D6FA 4U1BA 4S2RP 2BHAA 3IL0A 3PEBA 5CE6A 3PKCA 4IECA 4KM3A 3PKDA 5CDEA 3PN9A 2G6PA 3L24A 2GU4A 4FLJA 3CB6A 1YW7A 2V3XA 2GU6A 3Q6DA 4B28A 4ZNGA 2GU5A 1N51A 1XNZA 1W2MA 2B3KA 2BWUA 4QR8A 4RZYA 3RVAA 4U70A 1WN1A 2BWYA 1R5GA 2BWTA 2Q93A 4U76A 1KQ0A 2MATA 4ZWUA 2GG9A 2Q94A 4MATA 4S01A 5FCHA 1QZYA 1WY2A 2Q96A 1QXZA 5CIKA 3PKEA 1WBQA 1C21A 1WL6A 2GG8A 2OKNA 2IW2A 3PKBA 1KQ9A 4IKTA 5JHUA 3MX6A 2GTXA 4IU6A 2ADUA 5JFRA 4RGZ1 2EVMA 3QOCA 2GGBA 2GG7A 4OOKA 1XGNA 2GGCA 4U6ZA 3IG4A 2OAZA 1C22A 3FM3A 4HXXA 2B3HA 1MATA 1M35A 2V6CA 3MATA 3PKAA 4IKSA 2EA4A 1A16A 2BWSA 4IF7A 4U6JA 1YW9A 2NQ7A 1XGOA 2NQ6A 2GG2A 2BHBA 1CHMA 4ZWPA 3CB5A 3S6BA 2BH3A 5JI6A 2GG0A 5FCFA 2EVOA 4A6VA 2GZ5A 2P99A 3RORA 5E5BA 1Y1NA 1WKMA 4U6WA 4FLLA 1XGMA 2BWVA 4FO7A 2HOWA 1O0XA 4FUKA 1WLRA 5CDLA 1YJ3A 4IDYA 1QXWA 3BITA 2GU7A 2Q8KA 4FKCA 4ZWOA 3FMQA 4EGEA 2BWXA 2BN7A 4U71A 4IKRA 2ZSGA 1R5HA 4U69A 1XGSA 3IU7A 3BIPA 1JAWA 2GG3A 1YVMA 2GA2A 1C27A 2DFIA 3MR1A 4U73A 1PV9A 4S2TP 2V3YA 2BWWA 3CTZA 5E2CA 2BB7A 2GG5A 5CDVA 1QXYA 2Q92A 4R60A 1B59A 4FLIA 2V3ZA 1BN5A 3IU8A 1KP0A 4S00A 1B6AA 4RZZA 3TAVA 2Q95A 3L7GA 2BHDA 3OVKA 1YW8A 2B3LA 1C23A 4PV4A 3TB5A 4JUQA 3D27A 4Z7MA 3FMRA 4IPAA 3OOOA
chains in the Genus database with same CATH topology
1BOAA 1W7VA 4U6EA 4PNCA 3IU9A 2BHCA 2EVCA 3BIQA 5CLSA 2P9AA 4U75A 2EA2A 1R58A 4A6WA 4IKUA 4FLKA 2P98A 1WL9A 3O5VA 4FO8A 5CNXA 1C24A 4U6CA 5D6EA 3I7MA 5D6FA 4U1BA 4S2RP 2BHAA 3IL0A 3PEBA 5CE6A 3PKCA 4IECA 4KM3A 3PKDA 5CDEA 3PN9A 2G6PA 3L24A 2GU4A 4FLJA 3CB6A 1YW7A 2V3XA 2GU6A 3Q6DA 4B28A 4ZNGA 2GU5A 1N51A 1XNZA 1W2MA 2B3KA 2BWUA 4QR8A 4RZYA 3RVAA 4U70A 1WN1A 2BWYA 1R5GA 2BWTA 2Q93A 4U76A 1KQ0A 2MATA 4ZWUA 2GG9A 2Q94A 4MATA 4S01A 5FCHA 1QZYA 1WY2A 2Q96A 1QXZA 5CIKA 3PKEA 1WBQA 1C21A 1WL6A 2GG8A 2OKNA 2IW2A 3PKBA 1KQ9A 4IKTA 5JHUA 3MX6A 2GTXA 4IU6A 2ADUA 5JFRA 4RGZ1 2EVMA 3QOCA 2GGBA 2GG7A 4OOKA 1XGNA 2GGCA 4U6ZA 3IG4A 2OAZA 1C22A 3FM3A 4HXXA 2B3HA 1MATA 1M35A 2V6CA 3MATA 3PKAA 4IKSA 2EA4A 1A16A 2BWSA 4IF7A 4U6JA 1YW9A 2NQ7A 1XGOA 2NQ6A 2GG2A 2BHBA 1CHMA 4ZWPA 3CB5A 3S6BA 2BH3A 5JI6A 2GG0A 5FCFA 2EVOA 4A6VA 2GZ5A 2P99A 3RORA 5E5BA 1Y1NA 1WKMA 4U6WA 4FLLA 1XGMA 2BWVA 4FO7A 2HOWA 1O0XA 4FUKA 1WLRA 5CDLA 1YJ3A 4IDYA 1QXWA 3BITA 2GU7A 2Q8KA 4FKCA 4ZWOA 3FMQA 4EGEA 2BWXA 2BN7A 4U71A 4IKRA 2ZSGA 1R5HA 4U69A 1XGSA 3IU7A 3BIPA 1JAWA 2GG3A 1YVMA 2GA2A 1C27A 2DFIA 3MR1A 4U73A 1PV9A 4S2TP 2V3YA 2BWWA 3CTZA 5E2CA 2BB7A 2GG5A 5CDVA 1QXYA 2Q92A 4R60A 1B59A 4FLIA 2V3ZA 1BN5A 3IU8A 1KP0A 4S00A 1B6AA 4RZZA 3TAVA 2Q95A 3L7GA 2BHDA 3OVKA 1YW8A 2B3LA 1C23A 4PV4A 3TB5A 4JUQA 3D27A 4Z7MA 3FMRA 4IPAA 3OOOA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BOA A;  1W7V A;  4U6E A;  4PNC A;  3IU9 A;  2BHC A;  2EVC A;  3BIQ A;  5CLS A;  2P9A A;  4U75 A;  2EA2 A;  1R58 A;  4A6W A;  4IKU A;  4FLK A;  2P98 A;  1WL9 A;  3O5V A;  4FO8 A;  5CNX A;  1C24 A;  4U6C A;  5D6E A;  3I7M A;  5D6F A;  4U1B A;  4S2R P;  2BHA A;  3IL0 A;  3PEB A;  5CE6 A;  3PKC A;  4IEC A;  4KM3 A;  3PKD A;  5CDE A;  3PN9 A;  2G6P A;  3L24 A;  2GU4 A;  4FLJ A;  3CB6 A;  1YW7 A;  2V3X A;  2GU6 A;  3Q6D A;  4B28 A;  4ZNG A;  2GU5 A;  1N51 A;  1XNZ A;  1W2M A;  2B3K A;  2BWU A;  4QR8 A;  4RZY A;  3RVA A;  4U70 A;  1WN1 A;  2BWY A;  1R5G A;  2BWT A;  2Q93 A;  4U76 A;  1KQ0 A;  2MAT A;  4ZWU A;  2GG9 A;  2Q94 A;  4MAT A;  4S01 A;  5FCH A;  1QZY A;  1WY2 A;  2Q96 A;  1QXZ A;  5CIK A;  3PKE A;  1WBQ A;  1C21 A;  1WL6 A;  2GG8 A;  2OKN A;  2IW2 A;  3PKB A;  1KQ9 A;  4IKT A;  5JHU A;  3MX6 A;  2GTX A;  4IU6 A;  2ADU A;  5JFR A;  4RGZ 1;  2EVM A;  3QOC A;  2GGB A;  2GG7 A;  4OOK A;  1XGN A;  2GGC A;  4U6Z A;  3IG4 A;  2OAZ A;  1C22 A;  3FM3 A;  4HXX A;  2B3H A;  1MAT A;  1M35 A;  2V6C A;  3MAT A;  3PKA A;  4IKS A;  2EA4 A;  1A16 A;  2BWS A;  4IF7 A;  4U6J A;  1YW9 A;  2NQ7 A;  1XGO A;  2NQ6 A;  2GG2 A;  2BHB A;  1CHM A;  4ZWP A;  3CB5 A;  3S6B A;  2BH3 A;  5JI6 A;  2GG0 A;  5FCF A;  2EVO A;  4A6V A;  2GZ5 A;  2P99 A;  3ROR A;  5E5B A;  1Y1N A;  1WKM A;  4U6W A;  4FLL A;  1XGM A;  2BWV A;  4FO7 A;  2HOW A;  1O0X A;  4FUK A;  1WLR A;  5CDL A;  1YJ3 A;  4IDY A;  1QXW A;  3BIT A;  2GU7 A;  2Q8K A;  4FKC A;  4ZWO A;  3FMQ A;  4EGE A;  2BWX A;  2BN7 A;  4U71 A;  4IKR A;  2ZSG A;  1R5H A;  4U69 A;  1XGS A;  3IU7 A;  3BIP A;  1JAW A;  2GG3 A;  1YVM A;  2GA2 A;  1C27 A;  2DFI A;  3MR1 A;  4U73 A;  1PV9 A;  4S2T P;  2V3Y A;  2BWW A;  3CTZ A;  5E2C A;  2BB7 A;  2GG5 A;  5CDV A;  1QXY A;  2Q92 A;  4R60 A;  1B59 A;  4FLI A;  2V3Z A;  1BN5 A;  3IU8 A;  1KP0 A;  4S00 A;  1B6A A;  4RZZ A;  3TAV A;  2Q95 A;  3L7G A;  2BHD A;  3OVK A;  1YW8 A;  2B3L A;  1C23 A;  4PV4 A;  3TB5 A;  4JUQ A;  3D27 A;  4Z7M A;  3FMR A;  4IPA A;  3OOO A; 
#chains in the Genus database with same CATH topology
 1BOA A;  1W7V A;  4U6E A;  4PNC A;  3IU9 A;  2BHC A;  2EVC A;  3BIQ A;  5CLS A;  2P9A A;  4U75 A;  2EA2 A;  1R58 A;  4A6W A;  4IKU A;  4FLK A;  2P98 A;  1WL9 A;  3O5V A;  4FO8 A;  5CNX A;  1C24 A;  4U6C A;  5D6E A;  3I7M A;  5D6F A;  4U1B A;  4S2R P;  2BHA A;  3IL0 A;  3PEB A;  5CE6 A;  3PKC A;  4IEC A;  4KM3 A;  3PKD A;  5CDE A;  3PN9 A;  2G6P A;  3L24 A;  2GU4 A;  4FLJ A;  3CB6 A;  1YW7 A;  2V3X A;  2GU6 A;  3Q6D A;  4B28 A;  4ZNG A;  2GU5 A;  1N51 A;  1XNZ A;  1W2M A;  2B3K A;  2BWU A;  4QR8 A;  4RZY A;  3RVA A;  4U70 A;  1WN1 A;  2BWY A;  1R5G A;  2BWT A;  2Q93 A;  4U76 A;  1KQ0 A;  2MAT A;  4ZWU A;  2GG9 A;  2Q94 A;  4MAT A;  4S01 A;  5FCH A;  1QZY A;  1WY2 A;  2Q96 A;  1QXZ A;  5CIK A;  3PKE A;  1WBQ A;  1C21 A;  1WL6 A;  2GG8 A;  2OKN A;  2IW2 A;  3PKB A;  1KQ9 A;  4IKT A;  5JHU A;  3MX6 A;  2GTX A;  4IU6 A;  2ADU A;  5JFR A;  4RGZ 1;  2EVM A;  3QOC A;  2GGB A;  2GG7 A;  4OOK A;  1XGN A;  2GGC A;  4U6Z A;  3IG4 A;  2OAZ A;  1C22 A;  3FM3 A;  4HXX A;  2B3H A;  1MAT A;  1M35 A;  2V6C A;  3MAT A;  3PKA A;  4IKS A;  2EA4 A;  1A16 A;  2BWS A;  4IF7 A;  4U6J A;  1YW9 A;  2NQ7 A;  1XGO A;  2NQ6 A;  2GG2 A;  2BHB A;  1CHM A;  4ZWP A;  3CB5 A;  3S6B A;  2BH3 A;  5JI6 A;  2GG0 A;  5FCF A;  2EVO A;  4A6V A;  2GZ5 A;  2P99 A;  3ROR A;  5E5B A;  1Y1N A;  1WKM A;  4U6W A;  4FLL A;  1XGM A;  2BWV A;  4FO7 A;  2HOW A;  1O0X A;  4FUK A;  1WLR A;  5CDL A;  1YJ3 A;  4IDY A;  1QXW A;  3BIT A;  2GU7 A;  2Q8K A;  4FKC A;  4ZWO A;  3FMQ A;  4EGE A;  2BWX A;  2BN7 A;  4U71 A;  4IKR A;  2ZSG A;  1R5H A;  4U69 A;  1XGS A;  3IU7 A;  3BIP A;  1JAW A;  2GG3 A;  1YVM A;  2GA2 A;  1C27 A;  2DFI A;  3MR1 A;  4U73 A;  1PV9 A;  4S2T P;  2V3Y A;  2BWW A;  3CTZ A;  5E2C A;  2BB7 A;  2GG5 A;  5CDV A;  1QXY A;  2Q92 A;  4R60 A;  1B59 A;  4FLI A;  2V3Z A;  1BN5 A;  3IU8 A;  1KP0 A;  4S00 A;  1B6A A;  4RZZ A;  3TAV A;  2Q95 A;  3L7G A;  2BHD A;  3OVK A;  1YW8 A;  2B3L A;  1C23 A;  4PV4 A;  3TB5 A;  4JUQ A;  3D27 A;  4Z7M A;  3FMR A;  4IPA A;  3OOO A; 
#chains in the Genus database with same CATH homology
 1BOA A;  1W7V A;  4U6E A;  4PNC A;  3IU9 A;  2BHC A;  2EVC A;  3BIQ A;  5CLS A;  2P9A A;  4U75 A;  2EA2 A;  1R58 A;  4A6W A;  4IKU A;  4FLK A;  2P98 A;  1WL9 A;  3O5V A;  4FO8 A;  5CNX A;  1C24 A;  4U6C A;  5D6E A;  3I7M A;  5D6F A;  4U1B A;  4S2R P;  2BHA A;  3IL0 A;  3PEB A;  5CE6 A;  3PKC A;  4IEC A;  4KM3 A;  3PKD A;  5CDE A;  3PN9 A;  2G6P A;  3L24 A;  2GU4 A;  4FLJ A;  3CB6 A;  1YW7 A;  2V3X A;  2GU6 A;  3Q6D A;  4B28 A;  4ZNG A;  2GU5 A;  1N51 A;  1XNZ A;  1W2M A;  2B3K A;  2BWU A;  4QR8 A;  4RZY A;  3RVA A;  4U70 A;  1WN1 A;  2BWY A;  1R5G A;  2BWT A;  2Q93 A;  4U76 A;  1KQ0 A;  2MAT A;  4ZWU A;  2GG9 A;  2Q94 A;  4MAT A;  4S01 A;  5FCH A;  1QZY A;  1WY2 A;  2Q96 A;  1QXZ A;  5CIK A;  3PKE A;  1WBQ A;  1C21 A;  1WL6 A;  2GG8 A;  2OKN A;  2IW2 A;  3PKB A;  1KQ9 A;  4IKT A;  5JHU A;  3MX6 A;  2GTX A;  4IU6 A;  2ADU A;  5JFR A;  4RGZ 1;  2EVM A;  3QOC A;  2GGB A;  2GG7 A;  4OOK A;  1XGN A;  2GGC A;  4U6Z A;  3IG4 A;  2OAZ A;  1C22 A;  3FM3 A;  4HXX A;  2B3H A;  1MAT A;  1M35 A;  2V6C A;  3MAT A;  3PKA A;  4IKS A;  2EA4 A;  1A16 A;  2BWS A;  4IF7 A;  4U6J A;  1YW9 A;  2NQ7 A;  1XGO A;  2NQ6 A;  2GG2 A;  2BHB A;  1CHM A;  4ZWP A;  3CB5 A;  3S6B A;  2BH3 A;  5JI6 A;  2GG0 A;  5FCF A;  2EVO A;  4A6V A;  2GZ5 A;  2P99 A;  3ROR A;  5E5B A;  1Y1N A;  1WKM A;  4U6W A;  4FLL A;  1XGM A;  2BWV A;  4FO7 A;  2HOW A;  1O0X A;  4FUK A;  1WLR A;  5CDL A;  1YJ3 A;  4IDY A;  1QXW A;  3BIT A;  2GU7 A;  2Q8K A;  4FKC A;  4ZWO A;  3FMQ A;  4EGE A;  2BWX A;  2BN7 A;  4U71 A;  4IKR A;  2ZSG A;  1R5H A;  4U69 A;  1XGS A;  3IU7 A;  3BIP A;  1JAW A;  2GG3 A;  1YVM A;  2GA2 A;  1C27 A;  2DFI A;  3MR1 A;  4U73 A;  1PV9 A;  4S2T P;  2V3Y A;  2BWW A;  3CTZ A;  5E2C A;  2BB7 A;  2GG5 A;  5CDV A;  1QXY A;  2Q92 A;  4R60 A;  1B59 A;  4FLI A;  2V3Z A;  1BN5 A;  3IU8 A;  1KP0 A;  4S00 A;  1B6A A;  4RZZ A;  3TAV A;  2Q95 A;  3L7G A;  2BHD A;  3OVK A;  1YW8 A;  2B3L A;  1C23 A;  4PV4 A;  3TB5 A;  4JUQ A;  3D27 A;  4Z7M A;  3FMR A;  4IPA A;  3OOO A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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