5FCHA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and zn bound
Total Genus 133
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
133
sequence length
398
structure length
398
Chain Sequence
STQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 133
structure length 398
sequence length 398
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fchA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fchA02
4IKUA 1WBQA 4IDYA 4U75A 2NQ6A 2BHDA 5JI6A 3PKAA 3QOCA 2GZ5A 2V6CA 1PV9A 1XGMA 2GG7A 2GU7A 4FKCA 4PV4A 1WL9A 5D6EA 1YW7A 4OOKA 5CNXA 3BITA 1C22A 1XGNA 3IL0A 4U1BA 4A6VA 3L24A 3OOOA 5E2CA 1M35A 1KQ9A 4PNCA 2B3LA 4ZWUA 3Q6DA 2BH3A 4U6JA 5FCFA 2V3YA 3BIQA 4R60A 4ZWOA 5CIKA 4U76A 2BHAA 2GG2A 5CDVA 5JFRA 4FO7A 3TB5A 4Z7MA 4S2RP 1MATA 2P99A 2Q92A 3FMRA 5JHUA 1R5GA 2GG0A 2GTXA 4FLJA 4U6EA 2GA2A 2ZSGA 2EVOA 2EVMA 4IKSA 2G6PA 2B3HA 5CDLA 3D27A 3CTZA 4FLIA 4IKRA 1WLRA 1QZYA 2V3XA 1WKMA 1C23A 1KP0A 2BWYA 1XGSA 5CLSA 1YVMA 1B59A 1R5HA 2BN7A 2OAZA 3FM3A 2Q8KA 3MR1A 4RZZA 3PEBA 4FLKA 1QXWA 3PN9A 2GU6A 2P98A 3O5VA 3IU9A 2BHCA 2BWTA 1YW9A 3IU8A 2BWVA 1W7VA 5FCHA 2BB7A 2BWUA 4IPAA 4HXXA 4U69A 3OVKA 2Q95A 2Q96A 2GU5A 2GG3A 4U6ZA 4U70A 1B6AA 4QR8A 1C24A 3MATA 3RVAA 4KM3A 2IW2A 4S01A 4U73A 1W2MA 4S00A 1C27A 3MX6A 2B3KA 2EA2A 3CB5A 2GG5A 4U6CA 4U6WA 2BWWA 2MATA 1WL6A 1CHMA 3PKBA 2Q93A 3PKEA 4IKTA 4EGEA 1R58A 2EA4A 2GG8A 1XNZA 1A16A 3S6BA 3CB6A 4IU6A 1XGOA 3FMQA 3PKDA 3L7GA 1C21A 2NQ7A 4FO8A 1JAWA 4FUKA 2HOWA 1O0XA 2GG9A 5CDEA 1QXZA 2P9AA 1N51A 1WY2A 1KQ0A 4U71A 1Y1NA 1YJ3A 3IG4A 5E5BA 4ZWPA 1BOAA 4IECA 3RORA 4B28A 2DFIA 2BHBA 4S2TP 2EVCA 1WN1A 2V3ZA 1BN5A 4FLLA 3TAVA 4MATA 3I7MA 3IU7A 4A6WA 1QXYA 4RZYA 2GU4A 2BWSA 2OKNA 5CE6A 3BIPA 2BWXA 2GGCA 4JUQA 1YW8A 4RGZ1 3PKCA 2Q94A 4IF7A 2ADUA 4ZNGA 5D6FA 2GGBA
chains in the Genus database with same CATH superfamily
4IKUA 1WBQA 4IDYA 4U75A 2NQ6A 2BHDA 5JI6A 3PKAA 3QOCA 2GZ5A 2V6CA 1PV9A 1XGMA 2GG7A 2GU7A 4FKCA 4PV4A 1WL9A 5D6EA 1YW7A 4OOKA 5CNXA 3BITA 1C22A 1XGNA 3IL0A 4U1BA 4A6VA 3L24A 3OOOA 5E2CA 1M35A 1KQ9A 4PNCA 2B3LA 4ZWUA 3Q6DA 2BH3A 4U6JA 5FCFA 2V3YA 3BIQA 4R60A 4ZWOA 5CIKA 4U76A 2BHAA 2GG2A 5CDVA 5JFRA 4FO7A 3TB5A 4Z7MA 4S2RP 1MATA 2P99A 2Q92A 3FMRA 5JHUA 1R5GA 2GG0A 2GTXA 4FLJA 4U6EA 2GA2A 2ZSGA 2EVOA 2EVMA 4IKSA 2G6PA 2B3HA 5CDLA 3D27A 3CTZA 4FLIA 4IKRA 1WLRA 1QZYA 2V3XA 1WKMA 1C23A 1KP0A 2BWYA 1XGSA 5CLSA 1YVMA 1B59A 1R5HA 2BN7A 2OAZA 3FM3A 2Q8KA 3MR1A 4RZZA 3PEBA 4FLKA 1QXWA 3PN9A 2GU6A 2P98A 3O5VA 3IU9A 2BHCA 2BWTA 1YW9A 3IU8A 2BWVA 1W7VA 5FCHA 2BB7A 2BWUA 4IPAA 4HXXA 4U69A 3OVKA 2Q95A 2Q96A 2GU5A 2GG3A 4U6ZA 4U70A 1B6AA 4QR8A 1C24A 3MATA 3RVAA 4KM3A 2IW2A 4S01A 4U73A 1W2MA 4S00A 1C27A 3MX6A 2B3KA 2EA2A 3CB5A 2GG5A 4U6CA 4U6WA 2BWWA 2MATA 1WL6A 1CHMA 3PKBA 2Q93A 3PKEA 4IKTA 4EGEA 1R58A 2EA4A 2GG8A 1XNZA 1A16A 3S6BA 3CB6A 4IU6A 1XGOA 3FMQA 3PKDA 3L7GA 1C21A 2NQ7A 4FO8A 1JAWA 4FUKA 2HOWA 1O0XA 2GG9A 5CDEA 1QXZA 2P9AA 1N51A 1WY2A 1KQ0A 4U71A 1Y1NA 1YJ3A 3IG4A 5E5BA 4ZWPA 1BOAA 4IECA 3RORA 4B28A 2DFIA 2BHBA 4S2TP 2EVCA 1WN1A 2V3ZA 1BN5A 4FLLA 3TAVA 4MATA 3I7MA 3IU7A 4A6WA 1QXYA 4RZYA 2GU4A 2BWSA 2OKNA 5CE6A 3BIPA 2BWXA 2GGCA 4JUQA 1YW8A 4RGZ1 3PKCA 2Q94A 4IF7A 2ADUA 4ZNGA 5D6FA 2GGBA
chains in the Genus database with same CATH topology
4IKUA 1WBQA 4IDYA 4U75A 2NQ6A 2BHDA 5JI6A 3PKAA 3QOCA 2GZ5A 2V6CA 1PV9A 1XGMA 2GG7A 2GU7A 4FKCA 4PV4A 1WL9A 5D6EA 1YW7A 4OOKA 5CNXA 3BITA 1C22A 1XGNA 3IL0A 4U1BA 4A6VA 3L24A 3OOOA 5E2CA 1M35A 1KQ9A 4PNCA 2B3LA 4ZWUA 3Q6DA 2BH3A 4U6JA 5FCFA 2V3YA 3BIQA 4R60A 4ZWOA 5CIKA 4U76A 2BHAA 2GG2A 5CDVA 5JFRA 4FO7A 3TB5A 4Z7MA 4S2RP 1MATA 2P99A 2Q92A 3FMRA 5JHUA 1R5GA 2GG0A 2GTXA 4FLJA 4U6EA 2GA2A 2ZSGA 2EVOA 2EVMA 4IKSA 2G6PA 2B3HA 5CDLA 3D27A 3CTZA 4FLIA 4IKRA 1WLRA 1QZYA 2V3XA 1WKMA 1C23A 1KP0A 2BWYA 1XGSA 5CLSA 1YVMA 1B59A 1R5HA 2BN7A 2OAZA 3FM3A 2Q8KA 3MR1A 4RZZA 3PEBA 4FLKA 1QXWA 3PN9A 2GU6A 2P98A 3O5VA 3IU9A 2BHCA 2BWTA 1YW9A 3IU8A 2BWVA 1W7VA 5FCHA 2BB7A 2BWUA 4IPAA 4HXXA 4U69A 3OVKA 2Q95A 2Q96A 2GU5A 2GG3A 4U6ZA 4U70A 1B6AA 4QR8A 1C24A 3MATA 3RVAA 4KM3A 2IW2A 4S01A 4U73A 1W2MA 4S00A 1C27A 3MX6A 2B3KA 2EA2A 3CB5A 2GG5A 4U6CA 4U6WA 2BWWA 2MATA 1WL6A 1CHMA 3PKBA 2Q93A 3PKEA 4IKTA 4EGEA 1R58A 2EA4A 2GG8A 1XNZA 1A16A 3S6BA 3CB6A 4IU6A 1XGOA 3FMQA 3PKDA 3L7GA 1C21A 2NQ7A 4FO8A 1JAWA 4FUKA 2HOWA 1O0XA 2GG9A 5CDEA 1QXZA 2P9AA 1N51A 1WY2A 1KQ0A 4U71A 1Y1NA 1YJ3A 3IG4A 5E5BA 4ZWPA 1BOAA 4IECA 3RORA 4B28A 2DFIA 2BHBA 4S2TP 2EVCA 1WN1A 2V3ZA 1BN5A 4FLLA 3TAVA 4MATA 3I7MA 3IU7A 4A6WA 1QXYA 4RZYA 2GU4A 2BWSA 2OKNA 5CE6A 3BIPA 2BWXA 2GGCA 4JUQA 1YW8A 4RGZ1 3PKCA 2Q94A 4IF7A 2ADUA 4ZNGA 5D6FA 2GGBA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKU A;  1WBQ A;  4IDY A;  4U75 A;  2NQ6 A;  2BHD A;  5JI6 A;  3PKA A;  3QOC A;  2GZ5 A;  2V6C A;  1PV9 A;  1XGM A;  2GG7 A;  2GU7 A;  4FKC A;  4PV4 A;  1WL9 A;  5D6E A;  1YW7 A;  4OOK A;  5CNX A;  3BIT A;  1C22 A;  1XGN A;  3IL0 A;  4U1B A;  4A6V A;  3L24 A;  3OOO A;  5E2C A;  1M35 A;  1KQ9 A;  4PNC A;  2B3L A;  4ZWU A;  3Q6D A;  2BH3 A;  4U6J A;  5FCF A;  2V3Y A;  3BIQ A;  4R60 A;  4ZWO A;  5CIK A;  4U76 A;  2BHA A;  2GG2 A;  5CDV A;  5JFR A;  4FO7 A;  3TB5 A;  4Z7M A;  4S2R P;  1MAT A;  2P99 A;  2Q92 A;  3FMR A;  5JHU A;  1R5G A;  2GG0 A;  2GTX A;  4FLJ A;  4U6E A;  2GA2 A;  2ZSG A;  2EVO A;  2EVM A;  4IKS A;  2G6P A;  2B3H A;  5CDL A;  3D27 A;  3CTZ A;  4FLI A;  4IKR A;  1WLR A;  1QZY A;  2V3X A;  1WKM A;  1C23 A;  1KP0 A;  2BWY A;  1XGS A;  5CLS A;  1YVM A;  1B59 A;  1R5H A;  2BN7 A;  2OAZ A;  3FM3 A;  2Q8K A;  3MR1 A;  4RZZ A;  3PEB A;  4FLK A;  1QXW A;  3PN9 A;  2GU6 A;  2P98 A;  3O5V A;  3IU9 A;  2BHC A;  2BWT A;  1YW9 A;  3IU8 A;  2BWV A;  1W7V A;  5FCH A;  2BB7 A;  2BWU A;  4IPA A;  4HXX A;  4U69 A;  3OVK A;  2Q95 A;  2Q96 A;  2GU5 A;  2GG3 A;  4U6Z A;  4U70 A;  1B6A A;  4QR8 A;  1C24 A;  3MAT A;  3RVA A;  4KM3 A;  2IW2 A;  4S01 A;  4U73 A;  1W2M A;  4S00 A;  1C27 A;  3MX6 A;  2B3K A;  2EA2 A;  3CB5 A;  2GG5 A;  4U6C A;  4U6W A;  2BWW A;  2MAT A;  1WL6 A;  1CHM A;  3PKB A;  2Q93 A;  3PKE A;  4IKT A;  4EGE A;  1R58 A;  2EA4 A;  2GG8 A;  1XNZ A;  1A16 A;  3S6B A;  3CB6 A;  4IU6 A;  1XGO A;  3FMQ A;  3PKD A;  3L7G A;  1C21 A;  2NQ7 A;  4FO8 A;  1JAW A;  4FUK A;  2HOW A;  1O0X A;  2GG9 A;  5CDE A;  1QXZ A;  2P9A A;  1N51 A;  1WY2 A;  1KQ0 A;  4U71 A;  1Y1N A;  1YJ3 A;  3IG4 A;  5E5B A;  4ZWP A;  1BOA A;  4IEC A;  3ROR A;  4B28 A;  2DFI A;  2BHB A;  4S2T P;  2EVC A;  1WN1 A;  2V3Z A;  1BN5 A;  4FLL A;  3TAV A;  4MAT A;  3I7M A;  3IU7 A;  4A6W A;  1QXY A;  4RZY A;  2GU4 A;  2BWS A;  2OKN A;  5CE6 A;  3BIP A;  2BWX A;  2GGC A;  4JUQ A;  1YW8 A;  4RGZ 1;  3PKC A;  2Q94 A;  4IF7 A;  2ADU A;  4ZNG A;  5D6F A;  2GGB A; 
#chains in the Genus database with same CATH topology
 4IKU A;  1WBQ A;  4IDY A;  4U75 A;  2NQ6 A;  2BHD A;  5JI6 A;  3PKA A;  3QOC A;  2GZ5 A;  2V6C A;  1PV9 A;  1XGM A;  2GG7 A;  2GU7 A;  4FKC A;  4PV4 A;  1WL9 A;  5D6E A;  1YW7 A;  4OOK A;  5CNX A;  3BIT A;  1C22 A;  1XGN A;  3IL0 A;  4U1B A;  4A6V A;  3L24 A;  3OOO A;  5E2C A;  1M35 A;  1KQ9 A;  4PNC A;  2B3L A;  4ZWU A;  3Q6D A;  2BH3 A;  4U6J A;  5FCF A;  2V3Y A;  3BIQ A;  4R60 A;  4ZWO A;  5CIK A;  4U76 A;  2BHA A;  2GG2 A;  5CDV A;  5JFR A;  4FO7 A;  3TB5 A;  4Z7M A;  4S2R P;  1MAT A;  2P99 A;  2Q92 A;  3FMR A;  5JHU A;  1R5G A;  2GG0 A;  2GTX A;  4FLJ A;  4U6E A;  2GA2 A;  2ZSG A;  2EVO A;  2EVM A;  4IKS A;  2G6P A;  2B3H A;  5CDL A;  3D27 A;  3CTZ A;  4FLI A;  4IKR A;  1WLR A;  1QZY A;  2V3X A;  1WKM A;  1C23 A;  1KP0 A;  2BWY A;  1XGS A;  5CLS A;  1YVM A;  1B59 A;  1R5H A;  2BN7 A;  2OAZ A;  3FM3 A;  2Q8K A;  3MR1 A;  4RZZ A;  3PEB A;  4FLK A;  1QXW A;  3PN9 A;  2GU6 A;  2P98 A;  3O5V A;  3IU9 A;  2BHC A;  2BWT A;  1YW9 A;  3IU8 A;  2BWV A;  1W7V A;  5FCH A;  2BB7 A;  2BWU A;  4IPA A;  4HXX A;  4U69 A;  3OVK A;  2Q95 A;  2Q96 A;  2GU5 A;  2GG3 A;  4U6Z A;  4U70 A;  1B6A A;  4QR8 A;  1C24 A;  3MAT A;  3RVA A;  4KM3 A;  2IW2 A;  4S01 A;  4U73 A;  1W2M A;  4S00 A;  1C27 A;  3MX6 A;  2B3K A;  2EA2 A;  3CB5 A;  2GG5 A;  4U6C A;  4U6W A;  2BWW A;  2MAT A;  1WL6 A;  1CHM A;  3PKB A;  2Q93 A;  3PKE A;  4IKT A;  4EGE A;  1R58 A;  2EA4 A;  2GG8 A;  1XNZ A;  1A16 A;  3S6B A;  3CB6 A;  4IU6 A;  1XGO A;  3FMQ A;  3PKD A;  3L7G A;  1C21 A;  2NQ7 A;  4FO8 A;  1JAW A;  4FUK A;  2HOW A;  1O0X A;  2GG9 A;  5CDE A;  1QXZ A;  2P9A A;  1N51 A;  1WY2 A;  1KQ0 A;  4U71 A;  1Y1N A;  1YJ3 A;  3IG4 A;  5E5B A;  4ZWP A;  1BOA A;  4IEC A;  3ROR A;  4B28 A;  2DFI A;  2BHB A;  4S2T P;  2EVC A;  1WN1 A;  2V3Z A;  1BN5 A;  4FLL A;  3TAV A;  4MAT A;  3I7M A;  3IU7 A;  4A6W A;  1QXY A;  4RZY A;  2GU4 A;  2BWS A;  2OKN A;  5CE6 A;  3BIP A;  2BWX A;  2GGC A;  4JUQ A;  1YW8 A;  4RGZ 1;  3PKC A;  2Q94 A;  4IF7 A;  2ADU A;  4ZNG A;  5D6F A;  2GGB A; 
#chains in the Genus database with same CATH homology
 4IKU A;  1WBQ A;  4IDY A;  4U75 A;  2NQ6 A;  2BHD A;  5JI6 A;  3PKA A;  3QOC A;  2GZ5 A;  2V6C A;  1PV9 A;  1XGM A;  2GG7 A;  2GU7 A;  4FKC A;  4PV4 A;  1WL9 A;  5D6E A;  1YW7 A;  4OOK A;  5CNX A;  3BIT A;  1C22 A;  1XGN A;  3IL0 A;  4U1B A;  4A6V A;  3L24 A;  3OOO A;  5E2C A;  1M35 A;  1KQ9 A;  4PNC A;  2B3L A;  4ZWU A;  3Q6D A;  2BH3 A;  4U6J A;  5FCF A;  2V3Y A;  3BIQ A;  4R60 A;  4ZWO A;  5CIK A;  4U76 A;  2BHA A;  2GG2 A;  5CDV A;  5JFR A;  4FO7 A;  3TB5 A;  4Z7M A;  4S2R P;  1MAT A;  2P99 A;  2Q92 A;  3FMR A;  5JHU A;  1R5G A;  2GG0 A;  2GTX A;  4FLJ A;  4U6E A;  2GA2 A;  2ZSG A;  2EVO A;  2EVM A;  4IKS A;  2G6P A;  2B3H A;  5CDL A;  3D27 A;  3CTZ A;  4FLI A;  4IKR A;  1WLR A;  1QZY A;  2V3X A;  1WKM A;  1C23 A;  1KP0 A;  2BWY A;  1XGS A;  5CLS A;  1YVM A;  1B59 A;  1R5H A;  2BN7 A;  2OAZ A;  3FM3 A;  2Q8K A;  3MR1 A;  4RZZ A;  3PEB A;  4FLK A;  1QXW A;  3PN9 A;  2GU6 A;  2P98 A;  3O5V A;  3IU9 A;  2BHC A;  2BWT A;  1YW9 A;  3IU8 A;  2BWV A;  1W7V A;  5FCH A;  2BB7 A;  2BWU A;  4IPA A;  4HXX A;  4U69 A;  3OVK A;  2Q95 A;  2Q96 A;  2GU5 A;  2GG3 A;  4U6Z A;  4U70 A;  1B6A A;  4QR8 A;  1C24 A;  3MAT A;  3RVA A;  4KM3 A;  2IW2 A;  4S01 A;  4U73 A;  1W2M A;  4S00 A;  1C27 A;  3MX6 A;  2B3K A;  2EA2 A;  3CB5 A;  2GG5 A;  4U6C A;  4U6W A;  2BWW A;  2MAT A;  1WL6 A;  1CHM A;  3PKB A;  2Q93 A;  3PKE A;  4IKT A;  4EGE A;  1R58 A;  2EA4 A;  2GG8 A;  1XNZ A;  1A16 A;  3S6B A;  3CB6 A;  4IU6 A;  1XGO A;  3FMQ A;  3PKD A;  3L7G A;  1C21 A;  2NQ7 A;  4FO8 A;  1JAW A;  4FUK A;  2HOW A;  1O0X A;  2GG9 A;  5CDE A;  1QXZ A;  2P9A A;  1N51 A;  1WY2 A;  1KQ0 A;  4U71 A;  1Y1N A;  1YJ3 A;  3IG4 A;  5E5B A;  4ZWP A;  1BOA A;  4IEC A;  3ROR A;  4B28 A;  2DFI A;  2BHB A;  4S2T P;  2EVC A;  1WN1 A;  2V3Z A;  1BN5 A;  4FLL A;  3TAV A;  4MAT A;  3I7M A;  3IU7 A;  4A6W A;  1QXY A;  4RZY A;  2GU4 A;  2BWS A;  2OKN A;  5CE6 A;  3BIP A;  2BWX A;  2GGC A;  4JUQ A;  1YW8 A;  4RGZ 1;  3PKC A;  2Q94 A;  4IF7 A;  2ADU A;  4ZNG A;  5D6F A;  2GGB A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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