3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
source organism Enterococcus faecalis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
2P98A 2BWTA 2V3YA 1WY2A 4FLKA 4EGEA 4U6WA 3FMRA 2GZ5A 1KQ9A 1YW8A 1WBQA 4IKUA 4S00A 2Q96A 1R5HA 4FLLA 1KP0A 2GU7A 2OKNA 5CDLA 4IKSA 1XGSA 2ADUA 2Q94A 1YW9A 3IU8A 2B3KA 4OOKA 4U6CA 3CTZA 4U70A 4HXXA 1N51A 2EVMA 1C22A 3IG4A 2P9AA 4U73A 1B6AA 2NQ7A 2GU6A 3BIPA 5JHUA 1WL9A 2BWVA 2EVCA 4IECA 1MATA 4FUKA 1BOAA 3D27A 2BWXA 4QR8A 4U6EA 2BWYA 2GGBA 3IU7A 1PV9A 4FO8A 2BHDA 4IPAA 4FLIA 1C23A 2BHCA 2GU4A 2GG8A 1XGNA 2GG0A 2Q93A 3L7GA 1R5GA 4ZNGA 3CB5A 4U71A 1WKMA 4R60A 1QZYA 3CB6A 2BHAA 2EVOA 2BWWA 5JI6A 3FMQA 5FCHA 2GTXA 2Q8KA 2MATA 3MX6A 4U6ZA 4S2RP 2V3XA 3PKAA 3FM3A 2GGCA 4S01A 4B28A 1Y1NA 4FLJA 2BWSA 2G6PA 4ZWOA 1C27A 1YW7A 5CLSA 1JAWA 1WLRA 1QXZA 2B3HA 4IKTA 3RORA 3PKCA 4PNCA 2GU5A 2GG3A 4IF7A 4U1BA 2GA2A 4MATA 1C21A 5CIKA 2DFIA 4JUQA 2B3LA 2BH3A 1XNZA 4S2TP 4A6WA 2OAZA 2GG2A 3MATA 2Q95A 4RGZ1 2GG7A 1CHMA 2BHBA 2BN7A 3IU9A 5CDVA 4ZWPA 1W2MA 2GG5A 4U76A 5FCFA 2EA2A 1M35A 1XGOA 3TAVA 1C24A 1QXWA 4IU6A 2BB7A 2NQ6A 5CE6A 4A6VA 5D6FA 1WL6A 2Q92A 4Z7MA 5E5BA 1A16A 3RVAA 1BN5A 4KM3A 1KQ0A 1YVMA 1O0XA 2P99A 3L24A 3PKEA 4FO7A 4U69A 4U75A 5D6EA 2IW2A 1W7VA 2GG9A 2ZSGA 1YJ3A 4RZZA 5JFRA 1QXYA 4IKRA 3S6BA 2BWUA 1B59A 1XGMA 2HOWA 4U6JA 4IDYA 2EA4A 3PKDA 4PV4A 3Q6DA 3BITA 5CDEA 3TB5A 1WN1A 2V6CA 3BIQA 3PKBA 4FKCA 5CNXA 4RZYA 4ZWUA 3MR1A 1R58A 2V3ZA
chains in the Genus database with same CATH superfamily
2P98A 2BWTA 2V3YA 1WY2A 4FLKA 4EGEA 4U6WA 3FMRA 2GZ5A 1KQ9A 1YW8A 1WBQA 4IKUA 4S00A 2Q96A 1R5HA 4FLLA 1KP0A 2GU7A 2OKNA 5CDLA 4IKSA 1XGSA 2ADUA 2Q94A 1YW9A 3IU8A 2B3KA 4OOKA 4U6CA 3CTZA 4U70A 4HXXA 1N51A 2EVMA 1C22A 3IG4A 2P9AA 4U73A 1B6AA 2NQ7A 2GU6A 3BIPA 5JHUA 1WL9A 2BWVA 2EVCA 4IECA 1MATA 4FUKA 1BOAA 3D27A 2BWXA 4QR8A 4U6EA 2BWYA 2GGBA 3IU7A 1PV9A 4FO8A 2BHDA 4IPAA 4FLIA 1C23A 2BHCA 2GU4A 2GG8A 1XGNA 2GG0A 2Q93A 3L7GA 1R5GA 4ZNGA 3CB5A 4U71A 1WKMA 4R60A 1QZYA 3CB6A 2BHAA 2EVOA 2BWWA 5JI6A 3FMQA 5FCHA 2GTXA 2Q8KA 2MATA 3MX6A 4U6ZA 4S2RP 2V3XA 3PKAA 3FM3A 2GGCA 4S01A 4B28A 1Y1NA 4FLJA 2BWSA 2G6PA 4ZWOA 1C27A 1YW7A 5CLSA 1JAWA 1WLRA 1QXZA 2B3HA 4IKTA 3RORA 3PKCA 4PNCA 2GU5A 2GG3A 4IF7A 4U1BA 2GA2A 4MATA 1C21A 5CIKA 2DFIA 4JUQA 2B3LA 2BH3A 1XNZA 4S2TP 4A6WA 2OAZA 2GG2A 3MATA 2Q95A 4RGZ1 2GG7A 1CHMA 2BHBA 2BN7A 3IU9A 5CDVA 4ZWPA 1W2MA 2GG5A 4U76A 5FCFA 2EA2A 1M35A 1XGOA 3TAVA 1C24A 1QXWA 4IU6A 2BB7A 2NQ6A 5CE6A 4A6VA 5D6FA 1WL6A 2Q92A 4Z7MA 5E5BA 1A16A 3RVAA 1BN5A 4KM3A 1KQ0A 1YVMA 1O0XA 2P99A 3L24A 3PKEA 4FO7A 4U69A 4U75A 5D6EA 2IW2A 1W7VA 2GG9A 2ZSGA 1YJ3A 4RZZA 5JFRA 1QXYA 4IKRA 3S6BA 2BWUA 1B59A 1XGMA 2HOWA 4U6JA 4IDYA 2EA4A 3PKDA 4PV4A 3Q6DA 3BITA 5CDEA 3TB5A 1WN1A 2V6CA 3BIQA 3PKBA 4FKCA 5CNXA 4RZYA 4ZWUA 3MR1A 1R58A 2V3ZA
chains in the Genus database with same CATH topology
2P98A 2BWTA 2V3YA 1WY2A 4FLKA 4EGEA 4U6WA 3FMRA 2GZ5A 1KQ9A 1YW8A 1WBQA 4IKUA 4S00A 2Q96A 1R5HA 4FLLA 1KP0A 2GU7A 2OKNA 5CDLA 4IKSA 1XGSA 2ADUA 2Q94A 1YW9A 3IU8A 2B3KA 4OOKA 4U6CA 3CTZA 4U70A 4HXXA 1N51A 2EVMA 1C22A 3IG4A 2P9AA 4U73A 1B6AA 2NQ7A 2GU6A 3BIPA 5JHUA 1WL9A 2BWVA 2EVCA 4IECA 1MATA 4FUKA 1BOAA 3D27A 2BWXA 4QR8A 4U6EA 2BWYA 2GGBA 3IU7A 1PV9A 4FO8A 2BHDA 4IPAA 4FLIA 1C23A 2BHCA 2GU4A 2GG8A 1XGNA 2GG0A 2Q93A 3L7GA 1R5GA 4ZNGA 3CB5A 4U71A 1WKMA 4R60A 1QZYA 3CB6A 2BHAA 2EVOA 2BWWA 5JI6A 3FMQA 5FCHA 2GTXA 2Q8KA 2MATA 3MX6A 4U6ZA 4S2RP 2V3XA 3PKAA 3FM3A 2GGCA 4S01A 4B28A 1Y1NA 4FLJA 2BWSA 2G6PA 4ZWOA 1C27A 1YW7A 5CLSA 1JAWA 1WLRA 1QXZA 2B3HA 4IKTA 3RORA 3PKCA 4PNCA 2GU5A 2GG3A 4IF7A 4U1BA 2GA2A 4MATA 1C21A 5CIKA 2DFIA 4JUQA 2B3LA 2BH3A 1XNZA 4S2TP 4A6WA 2OAZA 2GG2A 3MATA 2Q95A 4RGZ1 2GG7A 1CHMA 2BHBA 2BN7A 3IU9A 5CDVA 4ZWPA 1W2MA 2GG5A 4U76A 5FCFA 2EA2A 1M35A 1XGOA 3TAVA 1C24A 1QXWA 4IU6A 2BB7A 2NQ6A 5CE6A 4A6VA 5D6FA 1WL6A 2Q92A 4Z7MA 5E5BA 1A16A 3RVAA 1BN5A 4KM3A 1KQ0A 1YVMA 1O0XA 2P99A 3L24A 3PKEA 4FO7A 4U69A 4U75A 5D6EA 2IW2A 1W7VA 2GG9A 2ZSGA 1YJ3A 4RZZA 5JFRA 1QXYA 4IKRA 3S6BA 2BWUA 1B59A 1XGMA 2HOWA 4U6JA 4IDYA 2EA4A 3PKDA 4PV4A 3Q6DA 3BITA 5CDEA 3TB5A 1WN1A 2V6CA 3BIQA 3PKBA 4FKCA 5CNXA 4RZYA 4ZWUA 3MR1A 1R58A 2V3ZA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2P98 A;  2BWT A;  2V3Y A;  1WY2 A;  4FLK A;  4EGE A;  4U6W A;  3FMR A;  2GZ5 A;  1KQ9 A;  1YW8 A;  1WBQ A;  4IKU A;  4S00 A;  2Q96 A;  1R5H A;  4FLL A;  1KP0 A;  2GU7 A;  2OKN A;  5CDL A;  4IKS A;  1XGS A;  2ADU A;  2Q94 A;  1YW9 A;  3IU8 A;  2B3K A;  4OOK A;  4U6C A;  3CTZ A;  4U70 A;  4HXX A;  1N51 A;  2EVM A;  1C22 A;  3IG4 A;  2P9A A;  4U73 A;  1B6A A;  2NQ7 A;  2GU6 A;  3BIP A;  5JHU A;  1WL9 A;  2BWV A;  2EVC A;  4IEC A;  1MAT A;  4FUK A;  1BOA A;  3D27 A;  2BWX A;  4QR8 A;  4U6E A;  2BWY A;  2GGB A;  3IU7 A;  1PV9 A;  4FO8 A;  2BHD A;  4IPA A;  4FLI A;  1C23 A;  2BHC A;  2GU4 A;  2GG8 A;  1XGN A;  2GG0 A;  2Q93 A;  3L7G A;  1R5G A;  4ZNG A;  3CB5 A;  4U71 A;  1WKM A;  4R60 A;  1QZY A;  3CB6 A;  2BHA A;  2EVO A;  2BWW A;  5JI6 A;  3FMQ A;  5FCH A;  2GTX A;  2Q8K A;  2MAT A;  3MX6 A;  4U6Z A;  4S2R P;  2V3X A;  3PKA A;  3FM3 A;  2GGC A;  4S01 A;  4B28 A;  1Y1N A;  4FLJ A;  2BWS A;  2G6P A;  4ZWO A;  1C27 A;  1YW7 A;  5CLS A;  1JAW A;  1WLR A;  1QXZ A;  2B3H A;  4IKT A;  3ROR A;  3PKC A;  4PNC A;  2GU5 A;  2GG3 A;  4IF7 A;  4U1B A;  2GA2 A;  4MAT A;  1C21 A;  5CIK A;  2DFI A;  4JUQ A;  2B3L A;  2BH3 A;  1XNZ A;  4S2T P;  4A6W A;  2OAZ A;  2GG2 A;  3MAT A;  2Q95 A;  4RGZ 1;  2GG7 A;  1CHM A;  2BHB A;  2BN7 A;  3IU9 A;  5CDV A;  4ZWP A;  1W2M A;  2GG5 A;  4U76 A;  5FCF A;  2EA2 A;  1M35 A;  1XGO A;  3TAV A;  1C24 A;  1QXW A;  4IU6 A;  2BB7 A;  2NQ6 A;  5CE6 A;  4A6V A;  5D6F A;  1WL6 A;  2Q92 A;  4Z7M A;  5E5B A;  1A16 A;  3RVA A;  1BN5 A;  4KM3 A;  1KQ0 A;  1YVM A;  1O0X A;  2P99 A;  3L24 A;  3PKE A;  4FO7 A;  4U69 A;  4U75 A;  5D6E A;  2IW2 A;  1W7V A;  2GG9 A;  2ZSG A;  1YJ3 A;  4RZZ A;  5JFR A;  1QXY A;  4IKR A;  3S6B A;  2BWU A;  1B59 A;  1XGM A;  2HOW A;  4U6J A;  4IDY A;  2EA4 A;  3PKD A;  4PV4 A;  3Q6D A;  3BIT A;  5CDE A;  3TB5 A;  1WN1 A;  2V6C A;  3BIQ A;  3PKB A;  4FKC A;  5CNX A;  4RZY A;  4ZWU A;  3MR1 A;  1R58 A;  2V3Z A; 
#chains in the Genus database with same CATH topology
 2P98 A;  2BWT A;  2V3Y A;  1WY2 A;  4FLK A;  4EGE A;  4U6W A;  3FMR A;  2GZ5 A;  1KQ9 A;  1YW8 A;  1WBQ A;  4IKU A;  4S00 A;  2Q96 A;  1R5H A;  4FLL A;  1KP0 A;  2GU7 A;  2OKN A;  5CDL A;  4IKS A;  1XGS A;  2ADU A;  2Q94 A;  1YW9 A;  3IU8 A;  2B3K A;  4OOK A;  4U6C A;  3CTZ A;  4U70 A;  4HXX A;  1N51 A;  2EVM A;  1C22 A;  3IG4 A;  2P9A A;  4U73 A;  1B6A A;  2NQ7 A;  2GU6 A;  3BIP A;  5JHU A;  1WL9 A;  2BWV A;  2EVC A;  4IEC A;  1MAT A;  4FUK A;  1BOA A;  3D27 A;  2BWX A;  4QR8 A;  4U6E A;  2BWY A;  2GGB A;  3IU7 A;  1PV9 A;  4FO8 A;  2BHD A;  4IPA A;  4FLI A;  1C23 A;  2BHC A;  2GU4 A;  2GG8 A;  1XGN A;  2GG0 A;  2Q93 A;  3L7G A;  1R5G A;  4ZNG A;  3CB5 A;  4U71 A;  1WKM A;  4R60 A;  1QZY A;  3CB6 A;  2BHA A;  2EVO A;  2BWW A;  5JI6 A;  3FMQ A;  5FCH A;  2GTX A;  2Q8K A;  2MAT A;  3MX6 A;  4U6Z A;  4S2R P;  2V3X A;  3PKA A;  3FM3 A;  2GGC A;  4S01 A;  4B28 A;  1Y1N A;  4FLJ A;  2BWS A;  2G6P A;  4ZWO A;  1C27 A;  1YW7 A;  5CLS A;  1JAW A;  1WLR A;  1QXZ A;  2B3H A;  4IKT A;  3ROR A;  3PKC A;  4PNC A;  2GU5 A;  2GG3 A;  4IF7 A;  4U1B A;  2GA2 A;  4MAT A;  1C21 A;  5CIK A;  2DFI A;  4JUQ A;  2B3L A;  2BH3 A;  1XNZ A;  4S2T P;  4A6W A;  2OAZ A;  2GG2 A;  3MAT A;  2Q95 A;  4RGZ 1;  2GG7 A;  1CHM A;  2BHB A;  2BN7 A;  3IU9 A;  5CDV A;  4ZWP A;  1W2M A;  2GG5 A;  4U76 A;  5FCF A;  2EA2 A;  1M35 A;  1XGO A;  3TAV A;  1C24 A;  1QXW A;  4IU6 A;  2BB7 A;  2NQ6 A;  5CE6 A;  4A6V A;  5D6F A;  1WL6 A;  2Q92 A;  4Z7M A;  5E5B A;  1A16 A;  3RVA A;  1BN5 A;  4KM3 A;  1KQ0 A;  1YVM A;  1O0X A;  2P99 A;  3L24 A;  3PKE A;  4FO7 A;  4U69 A;  4U75 A;  5D6E A;  2IW2 A;  1W7V A;  2GG9 A;  2ZSG A;  1YJ3 A;  4RZZ A;  5JFR A;  1QXY A;  4IKR A;  3S6B A;  2BWU A;  1B59 A;  1XGM A;  2HOW A;  4U6J A;  4IDY A;  2EA4 A;  3PKD A;  4PV4 A;  3Q6D A;  3BIT A;  5CDE A;  3TB5 A;  1WN1 A;  2V6C A;  3BIQ A;  3PKB A;  4FKC A;  5CNX A;  4RZY A;  4ZWU A;  3MR1 A;  1R58 A;  2V3Z A; 
#chains in the Genus database with same CATH homology
 2P98 A;  2BWT A;  2V3Y A;  1WY2 A;  4FLK A;  4EGE A;  4U6W A;  3FMR A;  2GZ5 A;  1KQ9 A;  1YW8 A;  1WBQ A;  4IKU A;  4S00 A;  2Q96 A;  1R5H A;  4FLL A;  1KP0 A;  2GU7 A;  2OKN A;  5CDL A;  4IKS A;  1XGS A;  2ADU A;  2Q94 A;  1YW9 A;  3IU8 A;  2B3K A;  4OOK A;  4U6C A;  3CTZ A;  4U70 A;  4HXX A;  1N51 A;  2EVM A;  1C22 A;  3IG4 A;  2P9A A;  4U73 A;  1B6A A;  2NQ7 A;  2GU6 A;  3BIP A;  5JHU A;  1WL9 A;  2BWV A;  2EVC A;  4IEC A;  1MAT A;  4FUK A;  1BOA A;  3D27 A;  2BWX A;  4QR8 A;  4U6E A;  2BWY A;  2GGB A;  3IU7 A;  1PV9 A;  4FO8 A;  2BHD A;  4IPA A;  4FLI A;  1C23 A;  2BHC A;  2GU4 A;  2GG8 A;  1XGN A;  2GG0 A;  2Q93 A;  3L7G A;  1R5G A;  4ZNG A;  3CB5 A;  4U71 A;  1WKM A;  4R60 A;  1QZY A;  3CB6 A;  2BHA A;  2EVO A;  2BWW A;  5JI6 A;  3FMQ A;  5FCH A;  2GTX A;  2Q8K A;  2MAT A;  3MX6 A;  4U6Z A;  4S2R P;  2V3X A;  3PKA A;  3FM3 A;  2GGC A;  4S01 A;  4B28 A;  1Y1N A;  4FLJ A;  2BWS A;  2G6P A;  4ZWO A;  1C27 A;  1YW7 A;  5CLS A;  1JAW A;  1WLR A;  1QXZ A;  2B3H A;  4IKT A;  3ROR A;  3PKC A;  4PNC A;  2GU5 A;  2GG3 A;  4IF7 A;  4U1B A;  2GA2 A;  4MAT A;  1C21 A;  5CIK A;  2DFI A;  4JUQ A;  2B3L A;  2BH3 A;  1XNZ A;  4S2T P;  4A6W A;  2OAZ A;  2GG2 A;  3MAT A;  2Q95 A;  4RGZ 1;  2GG7 A;  1CHM A;  2BHB A;  2BN7 A;  3IU9 A;  5CDV A;  4ZWP A;  1W2M A;  2GG5 A;  4U76 A;  5FCF A;  2EA2 A;  1M35 A;  1XGO A;  3TAV A;  1C24 A;  1QXW A;  4IU6 A;  2BB7 A;  2NQ6 A;  5CE6 A;  4A6V A;  5D6F A;  1WL6 A;  2Q92 A;  4Z7M A;  5E5B A;  1A16 A;  3RVA A;  1BN5 A;  4KM3 A;  1KQ0 A;  1YVM A;  1O0X A;  2P99 A;  3L24 A;  3PKE A;  4FO7 A;  4U69 A;  4U75 A;  5D6E A;  2IW2 A;  1W7V A;  2GG9 A;  2ZSG A;  1YJ3 A;  4RZZ A;  5JFR A;  1QXY A;  4IKR A;  3S6B A;  2BWU A;  1B59 A;  1XGM A;  2HOW A;  4U6J A;  4IDY A;  2EA4 A;  3PKD A;  4PV4 A;  3Q6D A;  3BIT A;  5CDE A;  3TB5 A;  1WN1 A;  2V6C A;  3BIQ A;  3PKB A;  4FKC A;  5CNX A;  4RZY A;  4ZWU A;  3MR1 A;  1R58 A;  2V3Z A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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