3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
source organism Enterococcus faecalis
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
2GG0A 1C21A 3BIPA 2B3LA 4R60A 2OKNA 4ZWPA 1R5GA 4IKUA 4U71A 1KQ0A 1O0XA 1B59A 1C22A 4IKSA 3L7GA 3TB5A 1WBQA 1WL9A 4FLIA 2BH3A 2ZSGA 3MX6A 4FLLA 3RVAA 2GG9A 2BWVA 2GU5A 3L24A 4FUKA 4ZWOA 1XGMA 3IG4A 4FKCA 2BHAA 3PKCA 5JI6A 4RZYA 1YW8A 2B3KA 1B6AA 1MATA 4U76A 1JAWA 2V6CA 3D27A 3IU7A 4S2TP 4PV4A 4MATA 4Z7MA 4U1BA 2Q95A 2EA2A 2P99A 4S01A 4IECA 2NQ6A 3PKEA 4FLKA 2Q93A 1M35A 1XNZA 3RORA 4S2RP 1KP0A 1R58A 2GG7A 5CE6A 3IU9A 2EVOA 5D6EA 2BHCA 3MATA 1YW9A 4U6ZA 3PKDA 4U70A 2Q92A 4FO7A 1BOAA 2HOWA 3IU8A 3PKBA 1WN1A 4ZWUA 1C23A 2OAZA 2MATA 3CTZA 3FMRA 1WL6A 4U69A 2GZ5A 3TAVA 2GU7A 1KQ9A 1XGOA 2BN7A 2EVMA 2EA4A 1WKMA 3MR1A 1C27A 4FO8A 2EVCA 5FCFA 4QR8A 1QZYA 1YJ3A 3FM3A 1WLRA 4EGEA 5CDVA 2GU6A 1BN5A 1QXYA 2B3HA 4A6VA 3FMQA 4HXXA 1QXZA 2BWTA 2P9AA 3BITA 1XGSA 3BIQA 4IU6A 4U73A 5JFRA 2BHDA 2NQ7A 4B28A 2GG2A 2Q94A 4OOKA 2GA2A 2BWSA 4IKRA 2BWWA 1YW7A 2GTXA 1QXWA 2BWXA 4KM3A 4U75A 1W2MA 4PNCA 4U6EA 4RGZ1 2GG8A 4IF7A 5D6FA 4A6WA 3Q6DA 2P98A 4IPAA 1C24A 4FLJA 2BWYA 1CHMA 2IW2A 4RZZA 1YVMA 5CDEA 2BHBA 2GG5A 1R5HA 2V3YA 2GGBA 1W7VA 1PV9A 3CB5A 4IDYA 1WY2A 5CNXA 2Q8KA 5CLSA 4U6WA 5CIKA 2GGCA 5CDLA 4U6JA 3CB6A 1A16A 5E5BA 1XGNA 4U6CA 2V3XA 2GU4A 4JUQA 1N51A 2Q96A 5FCHA 2BB7A 4S00A 4IKTA 3S6BA 5JHUA 2G6PA 1Y1NA 2DFIA 2V3ZA 4ZNGA 3PKAA 2ADUA 2BWUA 2GG3A
chains in the Genus database with same CATH superfamily
2GG0A 1C21A 3BIPA 2B3LA 4R60A 2OKNA 4ZWPA 1R5GA 4IKUA 4U71A 1KQ0A 1O0XA 1B59A 1C22A 4IKSA 3L7GA 3TB5A 1WBQA 1WL9A 4FLIA 2BH3A 2ZSGA 3MX6A 4FLLA 3RVAA 2GG9A 2BWVA 2GU5A 3L24A 4FUKA 4ZWOA 1XGMA 3IG4A 4FKCA 2BHAA 3PKCA 5JI6A 4RZYA 1YW8A 2B3KA 1B6AA 1MATA 4U76A 1JAWA 2V6CA 3D27A 3IU7A 4S2TP 4PV4A 4MATA 4Z7MA 4U1BA 2Q95A 2EA2A 2P99A 4S01A 4IECA 2NQ6A 3PKEA 4FLKA 2Q93A 1M35A 1XNZA 3RORA 4S2RP 1KP0A 1R58A 2GG7A 5CE6A 3IU9A 2EVOA 5D6EA 2BHCA 3MATA 1YW9A 4U6ZA 3PKDA 4U70A 2Q92A 4FO7A 1BOAA 2HOWA 3IU8A 3PKBA 1WN1A 4ZWUA 1C23A 2OAZA 2MATA 3CTZA 3FMRA 1WL6A 4U69A 2GZ5A 3TAVA 2GU7A 1KQ9A 1XGOA 2BN7A 2EVMA 2EA4A 1WKMA 3MR1A 1C27A 4FO8A 2EVCA 5FCFA 4QR8A 1QZYA 1YJ3A 3FM3A 1WLRA 4EGEA 5CDVA 2GU6A 1BN5A 1QXYA 2B3HA 4A6VA 3FMQA 4HXXA 1QXZA 2BWTA 2P9AA 3BITA 1XGSA 3BIQA 4IU6A 4U73A 5JFRA 2BHDA 2NQ7A 4B28A 2GG2A 2Q94A 4OOKA 2GA2A 2BWSA 4IKRA 2BWWA 1YW7A 2GTXA 1QXWA 2BWXA 4KM3A 4U75A 1W2MA 4PNCA 4U6EA 4RGZ1 2GG8A 4IF7A 5D6FA 4A6WA 3Q6DA 2P98A 4IPAA 1C24A 4FLJA 2BWYA 1CHMA 2IW2A 4RZZA 1YVMA 5CDEA 2BHBA 2GG5A 1R5HA 2V3YA 2GGBA 1W7VA 1PV9A 3CB5A 4IDYA 1WY2A 5CNXA 2Q8KA 5CLSA 4U6WA 5CIKA 2GGCA 5CDLA 4U6JA 3CB6A 1A16A 5E5BA 1XGNA 4U6CA 2V3XA 2GU4A 4JUQA 1N51A 2Q96A 5FCHA 2BB7A 4S00A 4IKTA 3S6BA 5JHUA 2G6PA 1Y1NA 2DFIA 2V3ZA 4ZNGA 3PKAA 2ADUA 2BWUA 2GG3A
chains in the Genus database with same CATH topology
2GG0A 1C21A 3BIPA 2B3LA 4R60A 2OKNA 4ZWPA 1R5GA 4IKUA 4U71A 1KQ0A 1O0XA 1B59A 1C22A 4IKSA 3L7GA 3TB5A 1WBQA 1WL9A 4FLIA 2BH3A 2ZSGA 3MX6A 4FLLA 3RVAA 2GG9A 2BWVA 2GU5A 3L24A 4FUKA 4ZWOA 1XGMA 3IG4A 4FKCA 2BHAA 3PKCA 5JI6A 4RZYA 1YW8A 2B3KA 1B6AA 1MATA 4U76A 1JAWA 2V6CA 3D27A 3IU7A 4S2TP 4PV4A 4MATA 4Z7MA 4U1BA 2Q95A 2EA2A 2P99A 4S01A 4IECA 2NQ6A 3PKEA 4FLKA 2Q93A 1M35A 1XNZA 3RORA 4S2RP 1KP0A 1R58A 2GG7A 5CE6A 3IU9A 2EVOA 5D6EA 2BHCA 3MATA 1YW9A 4U6ZA 3PKDA 4U70A 2Q92A 4FO7A 1BOAA 2HOWA 3IU8A 3PKBA 1WN1A 4ZWUA 1C23A 2OAZA 2MATA 3CTZA 3FMRA 1WL6A 4U69A 2GZ5A 3TAVA 2GU7A 1KQ9A 1XGOA 2BN7A 2EVMA 2EA4A 1WKMA 3MR1A 1C27A 4FO8A 2EVCA 5FCFA 4QR8A 1QZYA 1YJ3A 3FM3A 1WLRA 4EGEA 5CDVA 2GU6A 1BN5A 1QXYA 2B3HA 4A6VA 3FMQA 4HXXA 1QXZA 2BWTA 2P9AA 3BITA 1XGSA 3BIQA 4IU6A 4U73A 5JFRA 2BHDA 2NQ7A 4B28A 2GG2A 2Q94A 4OOKA 2GA2A 2BWSA 4IKRA 2BWWA 1YW7A 2GTXA 1QXWA 2BWXA 4KM3A 4U75A 1W2MA 4PNCA 4U6EA 4RGZ1 2GG8A 4IF7A 5D6FA 4A6WA 3Q6DA 2P98A 4IPAA 1C24A 4FLJA 2BWYA 1CHMA 2IW2A 4RZZA 1YVMA 5CDEA 2BHBA 2GG5A 1R5HA 2V3YA 2GGBA 1W7VA 1PV9A 3CB5A 4IDYA 1WY2A 5CNXA 2Q8KA 5CLSA 4U6WA 5CIKA 2GGCA 5CDLA 4U6JA 3CB6A 1A16A 5E5BA 1XGNA 4U6CA 2V3XA 2GU4A 4JUQA 1N51A 2Q96A 5FCHA 2BB7A 4S00A 4IKTA 3S6BA 5JHUA 2G6PA 1Y1NA 2DFIA 2V3ZA 4ZNGA 3PKAA 2ADUA 2BWUA 2GG3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG0 A;  1C21 A;  3BIP A;  2B3L A;  4R60 A;  2OKN A;  4ZWP A;  1R5G A;  4IKU A;  4U71 A;  1KQ0 A;  1O0X A;  1B59 A;  1C22 A;  4IKS A;  3L7G A;  3TB5 A;  1WBQ A;  1WL9 A;  4FLI A;  2BH3 A;  2ZSG A;  3MX6 A;  4FLL A;  3RVA A;  2GG9 A;  2BWV A;  2GU5 A;  3L24 A;  4FUK A;  4ZWO A;  1XGM A;  3IG4 A;  4FKC A;  2BHA A;  3PKC A;  5JI6 A;  4RZY A;  1YW8 A;  2B3K A;  1B6A A;  1MAT A;  4U76 A;  1JAW A;  2V6C A;  3D27 A;  3IU7 A;  4S2T P;  4PV4 A;  4MAT A;  4Z7M A;  4U1B A;  2Q95 A;  2EA2 A;  2P99 A;  4S01 A;  4IEC A;  2NQ6 A;  3PKE A;  4FLK A;  2Q93 A;  1M35 A;  1XNZ A;  3ROR A;  4S2R P;  1KP0 A;  1R58 A;  2GG7 A;  5CE6 A;  3IU9 A;  2EVO A;  5D6E A;  2BHC A;  3MAT A;  1YW9 A;  4U6Z A;  3PKD A;  4U70 A;  2Q92 A;  4FO7 A;  1BOA A;  2HOW A;  3IU8 A;  3PKB A;  1WN1 A;  4ZWU A;  1C23 A;  2OAZ A;  2MAT A;  3CTZ A;  3FMR A;  1WL6 A;  4U69 A;  2GZ5 A;  3TAV A;  2GU7 A;  1KQ9 A;  1XGO A;  2BN7 A;  2EVM A;  2EA4 A;  1WKM A;  3MR1 A;  1C27 A;  4FO8 A;  2EVC A;  5FCF A;  4QR8 A;  1QZY A;  1YJ3 A;  3FM3 A;  1WLR A;  4EGE A;  5CDV A;  2GU6 A;  1BN5 A;  1QXY A;  2B3H A;  4A6V A;  3FMQ A;  4HXX A;  1QXZ A;  2BWT A;  2P9A A;  3BIT A;  1XGS A;  3BIQ A;  4IU6 A;  4U73 A;  5JFR A;  2BHD A;  2NQ7 A;  4B28 A;  2GG2 A;  2Q94 A;  4OOK A;  2GA2 A;  2BWS A;  4IKR A;  2BWW A;  1YW7 A;  2GTX A;  1QXW A;  2BWX A;  4KM3 A;  4U75 A;  1W2M A;  4PNC A;  4U6E A;  4RGZ 1;  2GG8 A;  4IF7 A;  5D6F A;  4A6W A;  3Q6D A;  2P98 A;  4IPA A;  1C24 A;  4FLJ A;  2BWY A;  1CHM A;  2IW2 A;  4RZZ A;  1YVM A;  5CDE A;  2BHB A;  2GG5 A;  1R5H A;  2V3Y A;  2GGB A;  1W7V A;  1PV9 A;  3CB5 A;  4IDY A;  1WY2 A;  5CNX A;  2Q8K A;  5CLS A;  4U6W A;  5CIK A;  2GGC A;  5CDL A;  4U6J A;  3CB6 A;  1A16 A;  5E5B A;  1XGN A;  4U6C A;  2V3X A;  2GU4 A;  4JUQ A;  1N51 A;  2Q96 A;  5FCH A;  2BB7 A;  4S00 A;  4IKT A;  3S6B A;  5JHU A;  2G6P A;  1Y1N A;  2DFI A;  2V3Z A;  4ZNG A;  3PKA A;  2ADU A;  2BWU A;  2GG3 A; 
#chains in the Genus database with same CATH topology
 2GG0 A;  1C21 A;  3BIP A;  2B3L A;  4R60 A;  2OKN A;  4ZWP A;  1R5G A;  4IKU A;  4U71 A;  1KQ0 A;  1O0X A;  1B59 A;  1C22 A;  4IKS A;  3L7G A;  3TB5 A;  1WBQ A;  1WL9 A;  4FLI A;  2BH3 A;  2ZSG A;  3MX6 A;  4FLL A;  3RVA A;  2GG9 A;  2BWV A;  2GU5 A;  3L24 A;  4FUK A;  4ZWO A;  1XGM A;  3IG4 A;  4FKC A;  2BHA A;  3PKC A;  5JI6 A;  4RZY A;  1YW8 A;  2B3K A;  1B6A A;  1MAT A;  4U76 A;  1JAW A;  2V6C A;  3D27 A;  3IU7 A;  4S2T P;  4PV4 A;  4MAT A;  4Z7M A;  4U1B A;  2Q95 A;  2EA2 A;  2P99 A;  4S01 A;  4IEC A;  2NQ6 A;  3PKE A;  4FLK A;  2Q93 A;  1M35 A;  1XNZ A;  3ROR A;  4S2R P;  1KP0 A;  1R58 A;  2GG7 A;  5CE6 A;  3IU9 A;  2EVO A;  5D6E A;  2BHC A;  3MAT A;  1YW9 A;  4U6Z A;  3PKD A;  4U70 A;  2Q92 A;  4FO7 A;  1BOA A;  2HOW A;  3IU8 A;  3PKB A;  1WN1 A;  4ZWU A;  1C23 A;  2OAZ A;  2MAT A;  3CTZ A;  3FMR A;  1WL6 A;  4U69 A;  2GZ5 A;  3TAV A;  2GU7 A;  1KQ9 A;  1XGO A;  2BN7 A;  2EVM A;  2EA4 A;  1WKM A;  3MR1 A;  1C27 A;  4FO8 A;  2EVC A;  5FCF A;  4QR8 A;  1QZY A;  1YJ3 A;  3FM3 A;  1WLR A;  4EGE A;  5CDV A;  2GU6 A;  1BN5 A;  1QXY A;  2B3H A;  4A6V A;  3FMQ A;  4HXX A;  1QXZ A;  2BWT A;  2P9A A;  3BIT A;  1XGS A;  3BIQ A;  4IU6 A;  4U73 A;  5JFR A;  2BHD A;  2NQ7 A;  4B28 A;  2GG2 A;  2Q94 A;  4OOK A;  2GA2 A;  2BWS A;  4IKR A;  2BWW A;  1YW7 A;  2GTX A;  1QXW A;  2BWX A;  4KM3 A;  4U75 A;  1W2M A;  4PNC A;  4U6E A;  4RGZ 1;  2GG8 A;  4IF7 A;  5D6F A;  4A6W A;  3Q6D A;  2P98 A;  4IPA A;  1C24 A;  4FLJ A;  2BWY A;  1CHM A;  2IW2 A;  4RZZ A;  1YVM A;  5CDE A;  2BHB A;  2GG5 A;  1R5H A;  2V3Y A;  2GGB A;  1W7V A;  1PV9 A;  3CB5 A;  4IDY A;  1WY2 A;  5CNX A;  2Q8K A;  5CLS A;  4U6W A;  5CIK A;  2GGC A;  5CDL A;  4U6J A;  3CB6 A;  1A16 A;  5E5B A;  1XGN A;  4U6C A;  2V3X A;  2GU4 A;  4JUQ A;  1N51 A;  2Q96 A;  5FCH A;  2BB7 A;  4S00 A;  4IKT A;  3S6B A;  5JHU A;  2G6P A;  1Y1N A;  2DFI A;  2V3Z A;  4ZNG A;  3PKA A;  2ADU A;  2BWU A;  2GG3 A; 
#chains in the Genus database with same CATH homology
 2GG0 A;  1C21 A;  3BIP A;  2B3L A;  4R60 A;  2OKN A;  4ZWP A;  1R5G A;  4IKU A;  4U71 A;  1KQ0 A;  1O0X A;  1B59 A;  1C22 A;  4IKS A;  3L7G A;  3TB5 A;  1WBQ A;  1WL9 A;  4FLI A;  2BH3 A;  2ZSG A;  3MX6 A;  4FLL A;  3RVA A;  2GG9 A;  2BWV A;  2GU5 A;  3L24 A;  4FUK A;  4ZWO A;  1XGM A;  3IG4 A;  4FKC A;  2BHA A;  3PKC A;  5JI6 A;  4RZY A;  1YW8 A;  2B3K A;  1B6A A;  1MAT A;  4U76 A;  1JAW A;  2V6C A;  3D27 A;  3IU7 A;  4S2T P;  4PV4 A;  4MAT A;  4Z7M A;  4U1B A;  2Q95 A;  2EA2 A;  2P99 A;  4S01 A;  4IEC A;  2NQ6 A;  3PKE A;  4FLK A;  2Q93 A;  1M35 A;  1XNZ A;  3ROR A;  4S2R P;  1KP0 A;  1R58 A;  2GG7 A;  5CE6 A;  3IU9 A;  2EVO A;  5D6E A;  2BHC A;  3MAT A;  1YW9 A;  4U6Z A;  3PKD A;  4U70 A;  2Q92 A;  4FO7 A;  1BOA A;  2HOW A;  3IU8 A;  3PKB A;  1WN1 A;  4ZWU A;  1C23 A;  2OAZ A;  2MAT A;  3CTZ A;  3FMR A;  1WL6 A;  4U69 A;  2GZ5 A;  3TAV A;  2GU7 A;  1KQ9 A;  1XGO A;  2BN7 A;  2EVM A;  2EA4 A;  1WKM A;  3MR1 A;  1C27 A;  4FO8 A;  2EVC A;  5FCF A;  4QR8 A;  1QZY A;  1YJ3 A;  3FM3 A;  1WLR A;  4EGE A;  5CDV A;  2GU6 A;  1BN5 A;  1QXY A;  2B3H A;  4A6V A;  3FMQ A;  4HXX A;  1QXZ A;  2BWT A;  2P9A A;  3BIT A;  1XGS A;  3BIQ A;  4IU6 A;  4U73 A;  5JFR A;  2BHD A;  2NQ7 A;  4B28 A;  2GG2 A;  2Q94 A;  4OOK A;  2GA2 A;  2BWS A;  4IKR A;  2BWW A;  1YW7 A;  2GTX A;  1QXW A;  2BWX A;  4KM3 A;  4U75 A;  1W2M A;  4PNC A;  4U6E A;  4RGZ 1;  2GG8 A;  4IF7 A;  5D6F A;  4A6W A;  3Q6D A;  2P98 A;  4IPA A;  1C24 A;  4FLJ A;  2BWY A;  1CHM A;  2IW2 A;  4RZZ A;  1YVM A;  5CDE A;  2BHB A;  2GG5 A;  1R5H A;  2V3Y A;  2GGB A;  1W7V A;  1PV9 A;  3CB5 A;  4IDY A;  1WY2 A;  5CNX A;  2Q8K A;  5CLS A;  4U6W A;  5CIK A;  2GGC A;  5CDL A;  4U6J A;  3CB6 A;  1A16 A;  5E5B A;  1XGN A;  4U6C A;  2V3X A;  2GU4 A;  4JUQ A;  1N51 A;  2Q96 A;  5FCH A;  2BB7 A;  4S00 A;  4IKT A;  3S6B A;  5JHU A;  2G6P A;  1Y1N A;  2DFI A;  2V3Z A;  4ZNG A;  3PKA A;  2ADU A;  2BWU A;  2GG3 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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