3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
b'MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
source organism Enterococcus faecalis
molecule tags Hydrolase
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
2BWXA 5E5BA 5FCFA 4ZWPA 4IECA 1XGNA 3PKCA 1YW7A 2Q92A 5FCHA 2Q96A 3L7GA 1M35A 1KQ9A 1R5HA 3TB5A 3TAVA 4ZWUA 2EA2A 3L24A 3PKAA 1CHMA 2G6PA 4HXXA 2Q95A 4U73A 5D6FA 1WBQA 1B59A 4U69A 2GG2A 4MATA 1XGMA 4U75A 3MATA 2BHAA 4S01A 4U1BA 2BH3A 3FMRA 4FLIA 2BHCA 4IDYA 2NQ7A 2B3HA 1WY2A 1BN5A 2EVCA 3PKBA 4RGZ1 1JAWA 2ADUA 1Y1NA 1WL9A 4U76A 2GZ5A 1MATA 4FO7A 2B3LA 5JI6A 4U6ZA 2GG8A 4OOKA 1YJ3A 1A16A 1YVMA 1WKMA 4PNCA 1XGOA 5CE6A 4U71A 3MR1A 1YW9A 1W7VA 3FMQA 3IU7A 3D27A 4IKSA 3BIQA 4U70A 1O0XA 4S2TP 1C21A 2GG5A 4A6WA 1WLRA 4S00A 1QXYA 2P98A 1KP0A 1PV9A 2V3XA 2GU4A 2OKNA 4ZNGA 4FO8A 2OAZA 2GU6A 5CDLA 2BWUA 2BWSA 1B6AA 4IKUA 2BN7A 2GGCA 1C22A 1QXWA 2BHDA 4U6CA 4KM3A 1YW8A 5CNXA 4QR8A 4IU6A 3RORA 1R5GA 5JHUA 2NQ6A 2GU7A 1C23A 5CLSA 5CDVA 5JFRA 2Q94A 2GG0A 1N51A 2P9AA 4R60A 2GG7A 4U6EA 5CDEA 2GA2A 4U6JA 3BITA 5CIKA 2BWVA 1C24A 4IPAA 1BOAA 1R58A 3PKDA 2B3KA 2BHBA 4RZZA 2MATA 2ZSGA 2EVOA 3CTZA 4FKCA 2Q8KA 1KQ0A 3Q6DA 1XNZA 2P99A 5D6EA 2Q93A 3CB6A 4FLKA 2V6CA 4IKTA 1QXZA 2V3ZA 3RVAA 2EA4A 1W2MA 1QZYA 4FUKA 4IKRA 4JUQA 2GGBA 2BB7A 2BWYA 2HOWA 4A6VA 3BIPA 2GTXA 4RZYA 4ZWOA 3CB5A 1WL6A 2IW2A 2DFIA 3FM3A 4S2RP 2BWTA 4FLLA 4B28A 4Z7MA 3IU9A 4IF7A 2BWWA 2GG3A 3IU8A 4FLJA 2EVMA 4U6WA 1C27A 2GU5A 2V3YA 3MX6A 1XGSA 4EGEA 3IG4A 3PKEA 4PV4A 2GG9A 1WN1A 3S6BA
chains in the Genus database with same CATH superfamily
2BWXA 5E5BA 5FCFA 4ZWPA 4IECA 1XGNA 3PKCA 1YW7A 2Q92A 5FCHA 2Q96A 3L7GA 1M35A 1KQ9A 1R5HA 3TB5A 3TAVA 4ZWUA 2EA2A 3L24A 3PKAA 1CHMA 2G6PA 4HXXA 2Q95A 4U73A 5D6FA 1WBQA 1B59A 4U69A 2GG2A 4MATA 1XGMA 4U75A 3MATA 2BHAA 4S01A 4U1BA 2BH3A 3FMRA 4FLIA 2BHCA 4IDYA 2NQ7A 2B3HA 1WY2A 1BN5A 2EVCA 3PKBA 4RGZ1 1JAWA 2ADUA 1Y1NA 1WL9A 4U76A 2GZ5A 1MATA 4FO7A 2B3LA 5JI6A 4U6ZA 2GG8A 4OOKA 1YJ3A 1A16A 1YVMA 1WKMA 4PNCA 1XGOA 5CE6A 4U71A 3MR1A 1YW9A 1W7VA 3FMQA 3IU7A 3D27A 4IKSA 3BIQA 4U70A 1O0XA 4S2TP 1C21A 2GG5A 4A6WA 1WLRA 4S00A 1QXYA 2P98A 1KP0A 1PV9A 2V3XA 2GU4A 2OKNA 4ZNGA 4FO8A 2OAZA 2GU6A 5CDLA 2BWUA 2BWSA 1B6AA 4IKUA 2BN7A 2GGCA 1C22A 1QXWA 2BHDA 4U6CA 4KM3A 1YW8A 5CNXA 4QR8A 4IU6A 3RORA 1R5GA 5JHUA 2NQ6A 2GU7A 1C23A 5CLSA 5CDVA 5JFRA 2Q94A 2GG0A 1N51A 2P9AA 4R60A 2GG7A 4U6EA 5CDEA 2GA2A 4U6JA 3BITA 5CIKA 2BWVA 1C24A 4IPAA 1BOAA 1R58A 3PKDA 2B3KA 2BHBA 4RZZA 2MATA 2ZSGA 2EVOA 3CTZA 4FKCA 2Q8KA 1KQ0A 3Q6DA 1XNZA 2P99A 5D6EA 2Q93A 3CB6A 4FLKA 2V6CA 4IKTA 1QXZA 2V3ZA 3RVAA 2EA4A 1W2MA 1QZYA 4FUKA 4IKRA 4JUQA 2GGBA 2BB7A 2BWYA 2HOWA 4A6VA 3BIPA 2GTXA 4RZYA 4ZWOA 3CB5A 1WL6A 2IW2A 2DFIA 3FM3A 4S2RP 2BWTA 4FLLA 4B28A 4Z7MA 3IU9A 4IF7A 2BWWA 2GG3A 3IU8A 4FLJA 2EVMA 4U6WA 1C27A 2GU5A 2V3YA 3MX6A 1XGSA 4EGEA 3IG4A 3PKEA 4PV4A 2GG9A 1WN1A 3S6BA
chains in the Genus database with same CATH topology
2BWXA 5E5BA 5FCFA 4ZWPA 4IECA 1XGNA 3PKCA 1YW7A 2Q92A 5FCHA 2Q96A 3L7GA 1M35A 1KQ9A 1R5HA 3TB5A 3TAVA 4ZWUA 2EA2A 3L24A 3PKAA 1CHMA 2G6PA 4HXXA 2Q95A 4U73A 5D6FA 1WBQA 1B59A 4U69A 2GG2A 4MATA 1XGMA 4U75A 3MATA 2BHAA 4S01A 4U1BA 2BH3A 3FMRA 4FLIA 2BHCA 4IDYA 2NQ7A 2B3HA 1WY2A 1BN5A 2EVCA 3PKBA 4RGZ1 1JAWA 2ADUA 1Y1NA 1WL9A 4U76A 2GZ5A 1MATA 4FO7A 2B3LA 5JI6A 4U6ZA 2GG8A 4OOKA 1YJ3A 1A16A 1YVMA 1WKMA 4PNCA 1XGOA 5CE6A 4U71A 3MR1A 1YW9A 1W7VA 3FMQA 3IU7A 3D27A 4IKSA 3BIQA 4U70A 1O0XA 4S2TP 1C21A 2GG5A 4A6WA 1WLRA 4S00A 1QXYA 2P98A 1KP0A 1PV9A 2V3XA 2GU4A 2OKNA 4ZNGA 4FO8A 2OAZA 2GU6A 5CDLA 2BWUA 2BWSA 1B6AA 4IKUA 2BN7A 2GGCA 1C22A 1QXWA 2BHDA 4U6CA 4KM3A 1YW8A 5CNXA 4QR8A 4IU6A 3RORA 1R5GA 5JHUA 2NQ6A 2GU7A 1C23A 5CLSA 5CDVA 5JFRA 2Q94A 2GG0A 1N51A 2P9AA 4R60A 2GG7A 4U6EA 5CDEA 2GA2A 4U6JA 3BITA 5CIKA 2BWVA 1C24A 4IPAA 1BOAA 1R58A 3PKDA 2B3KA 2BHBA 4RZZA 2MATA 2ZSGA 2EVOA 3CTZA 4FKCA 2Q8KA 1KQ0A 3Q6DA 1XNZA 2P99A 5D6EA 2Q93A 3CB6A 4FLKA 2V6CA 4IKTA 1QXZA 2V3ZA 3RVAA 2EA4A 1W2MA 1QZYA 4FUKA 4IKRA 4JUQA 2GGBA 2BB7A 2BWYA 2HOWA 4A6VA 3BIPA 2GTXA 4RZYA 4ZWOA 3CB5A 1WL6A 2IW2A 2DFIA 3FM3A 4S2RP 2BWTA 4FLLA 4B28A 4Z7MA 3IU9A 4IF7A 2BWWA 2GG3A 3IU8A 4FLJA 2EVMA 4U6WA 1C27A 2GU5A 2V3YA 3MX6A 1XGSA 4EGEA 3IG4A 3PKEA 4PV4A 2GG9A 1WN1A 3S6BA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2BWX A;  5E5B A;  5FCF A;  4ZWP A;  4IEC A;  1XGN A;  3PKC A;  1YW7 A;  2Q92 A;  5FCH A;  2Q96 A;  3L7G A;  1M35 A;  1KQ9 A;  1R5H A;  3TB5 A;  3TAV A;  4ZWU A;  2EA2 A;  3L24 A;  3PKA A;  1CHM A;  2G6P A;  4HXX A;  2Q95 A;  4U73 A;  5D6F A;  1WBQ A;  1B59 A;  4U69 A;  2GG2 A;  4MAT A;  1XGM A;  4U75 A;  3MAT A;  2BHA A;  4S01 A;  4U1B A;  2BH3 A;  3FMR A;  4FLI A;  2BHC A;  4IDY A;  2NQ7 A;  2B3H A;  1WY2 A;  1BN5 A;  2EVC A;  3PKB A;  4RGZ 1;  1JAW A;  2ADU A;  1Y1N A;  1WL9 A;  4U76 A;  2GZ5 A;  1MAT A;  4FO7 A;  2B3L A;  5JI6 A;  4U6Z A;  2GG8 A;  4OOK A;  1YJ3 A;  1A16 A;  1YVM A;  1WKM A;  4PNC A;  1XGO A;  5CE6 A;  4U71 A;  3MR1 A;  1YW9 A;  1W7V A;  3FMQ A;  3IU7 A;  3D27 A;  4IKS A;  3BIQ A;  4U70 A;  1O0X A;  4S2T P;  1C21 A;  2GG5 A;  4A6W A;  1WLR A;  4S00 A;  1QXY A;  2P98 A;  1KP0 A;  1PV9 A;  2V3X A;  2GU4 A;  2OKN A;  4ZNG A;  4FO8 A;  2OAZ A;  2GU6 A;  5CDL A;  2BWU A;  2BWS A;  1B6A A;  4IKU A;  2BN7 A;  2GGC A;  1C22 A;  1QXW A;  2BHD A;  4U6C A;  4KM3 A;  1YW8 A;  5CNX A;  4QR8 A;  4IU6 A;  3ROR A;  1R5G A;  5JHU A;  2NQ6 A;  2GU7 A;  1C23 A;  5CLS A;  5CDV A;  5JFR A;  2Q94 A;  2GG0 A;  1N51 A;  2P9A A;  4R60 A;  2GG7 A;  4U6E A;  5CDE A;  2GA2 A;  4U6J A;  3BIT A;  5CIK A;  2BWV A;  1C24 A;  4IPA A;  1BOA A;  1R58 A;  3PKD A;  2B3K A;  2BHB A;  4RZZ A;  2MAT A;  2ZSG A;  2EVO A;  3CTZ A;  4FKC A;  2Q8K A;  1KQ0 A;  3Q6D A;  1XNZ A;  2P99 A;  5D6E A;  2Q93 A;  3CB6 A;  4FLK A;  2V6C A;  4IKT A;  1QXZ A;  2V3Z A;  3RVA A;  2EA4 A;  1W2M A;  1QZY A;  4FUK A;  4IKR A;  4JUQ A;  2GGB A;  2BB7 A;  2BWY A;  2HOW A;  4A6V A;  3BIP A;  2GTX A;  4RZY A;  4ZWO A;  3CB5 A;  1WL6 A;  2IW2 A;  2DFI A;  3FM3 A;  4S2R P;  2BWT A;  4FLL A;  4B28 A;  4Z7M A;  3IU9 A;  4IF7 A;  2BWW A;  2GG3 A;  3IU8 A;  4FLJ A;  2EVM A;  4U6W A;  1C27 A;  2GU5 A;  2V3Y A;  3MX6 A;  1XGS A;  4EGE A;  3IG4 A;  3PKE A;  4PV4 A;  2GG9 A;  1WN1 A;  3S6B A; 
#chains in the Genus database with same CATH topology
 2BWX A;  5E5B A;  5FCF A;  4ZWP A;  4IEC A;  1XGN A;  3PKC A;  1YW7 A;  2Q92 A;  5FCH A;  2Q96 A;  3L7G A;  1M35 A;  1KQ9 A;  1R5H A;  3TB5 A;  3TAV A;  4ZWU A;  2EA2 A;  3L24 A;  3PKA A;  1CHM A;  2G6P A;  4HXX A;  2Q95 A;  4U73 A;  5D6F A;  1WBQ A;  1B59 A;  4U69 A;  2GG2 A;  4MAT A;  1XGM A;  4U75 A;  3MAT A;  2BHA A;  4S01 A;  4U1B A;  2BH3 A;  3FMR A;  4FLI A;  2BHC A;  4IDY A;  2NQ7 A;  2B3H A;  1WY2 A;  1BN5 A;  2EVC A;  3PKB A;  4RGZ 1;  1JAW A;  2ADU A;  1Y1N A;  1WL9 A;  4U76 A;  2GZ5 A;  1MAT A;  4FO7 A;  2B3L A;  5JI6 A;  4U6Z A;  2GG8 A;  4OOK A;  1YJ3 A;  1A16 A;  1YVM A;  1WKM A;  4PNC A;  1XGO A;  5CE6 A;  4U71 A;  3MR1 A;  1YW9 A;  1W7V A;  3FMQ A;  3IU7 A;  3D27 A;  4IKS A;  3BIQ A;  4U70 A;  1O0X A;  4S2T P;  1C21 A;  2GG5 A;  4A6W A;  1WLR A;  4S00 A;  1QXY A;  2P98 A;  1KP0 A;  1PV9 A;  2V3X A;  2GU4 A;  2OKN A;  4ZNG A;  4FO8 A;  2OAZ A;  2GU6 A;  5CDL A;  2BWU A;  2BWS A;  1B6A A;  4IKU A;  2BN7 A;  2GGC A;  1C22 A;  1QXW A;  2BHD A;  4U6C A;  4KM3 A;  1YW8 A;  5CNX A;  4QR8 A;  4IU6 A;  3ROR A;  1R5G A;  5JHU A;  2NQ6 A;  2GU7 A;  1C23 A;  5CLS A;  5CDV A;  5JFR A;  2Q94 A;  2GG0 A;  1N51 A;  2P9A A;  4R60 A;  2GG7 A;  4U6E A;  5CDE A;  2GA2 A;  4U6J A;  3BIT A;  5CIK A;  2BWV A;  1C24 A;  4IPA A;  1BOA A;  1R58 A;  3PKD A;  2B3K A;  2BHB A;  4RZZ A;  2MAT A;  2ZSG A;  2EVO A;  3CTZ A;  4FKC A;  2Q8K A;  1KQ0 A;  3Q6D A;  1XNZ A;  2P99 A;  5D6E A;  2Q93 A;  3CB6 A;  4FLK A;  2V6C A;  4IKT A;  1QXZ A;  2V3Z A;  3RVA A;  2EA4 A;  1W2M A;  1QZY A;  4FUK A;  4IKR A;  4JUQ A;  2GGB A;  2BB7 A;  2BWY A;  2HOW A;  4A6V A;  3BIP A;  2GTX A;  4RZY A;  4ZWO A;  3CB5 A;  1WL6 A;  2IW2 A;  2DFI A;  3FM3 A;  4S2R P;  2BWT A;  4FLL A;  4B28 A;  4Z7M A;  3IU9 A;  4IF7 A;  2BWW A;  2GG3 A;  3IU8 A;  4FLJ A;  2EVM A;  4U6W A;  1C27 A;  2GU5 A;  2V3Y A;  3MX6 A;  1XGS A;  4EGE A;  3IG4 A;  3PKE A;  4PV4 A;  2GG9 A;  1WN1 A;  3S6B A; 
#chains in the Genus database with same CATH homology
 2BWX A;  5E5B A;  5FCF A;  4ZWP A;  4IEC A;  1XGN A;  3PKC A;  1YW7 A;  2Q92 A;  5FCH A;  2Q96 A;  3L7G A;  1M35 A;  1KQ9 A;  1R5H A;  3TB5 A;  3TAV A;  4ZWU A;  2EA2 A;  3L24 A;  3PKA A;  1CHM A;  2G6P A;  4HXX A;  2Q95 A;  4U73 A;  5D6F A;  1WBQ A;  1B59 A;  4U69 A;  2GG2 A;  4MAT A;  1XGM A;  4U75 A;  3MAT A;  2BHA A;  4S01 A;  4U1B A;  2BH3 A;  3FMR A;  4FLI A;  2BHC A;  4IDY A;  2NQ7 A;  2B3H A;  1WY2 A;  1BN5 A;  2EVC A;  3PKB A;  4RGZ 1;  1JAW A;  2ADU A;  1Y1N A;  1WL9 A;  4U76 A;  2GZ5 A;  1MAT A;  4FO7 A;  2B3L A;  5JI6 A;  4U6Z A;  2GG8 A;  4OOK A;  1YJ3 A;  1A16 A;  1YVM A;  1WKM A;  4PNC A;  1XGO A;  5CE6 A;  4U71 A;  3MR1 A;  1YW9 A;  1W7V A;  3FMQ A;  3IU7 A;  3D27 A;  4IKS A;  3BIQ A;  4U70 A;  1O0X A;  4S2T P;  1C21 A;  2GG5 A;  4A6W A;  1WLR A;  4S00 A;  1QXY A;  2P98 A;  1KP0 A;  1PV9 A;  2V3X A;  2GU4 A;  2OKN A;  4ZNG A;  4FO8 A;  2OAZ A;  2GU6 A;  5CDL A;  2BWU A;  2BWS A;  1B6A A;  4IKU A;  2BN7 A;  2GGC A;  1C22 A;  1QXW A;  2BHD A;  4U6C A;  4KM3 A;  1YW8 A;  5CNX A;  4QR8 A;  4IU6 A;  3ROR A;  1R5G A;  5JHU A;  2NQ6 A;  2GU7 A;  1C23 A;  5CLS A;  5CDV A;  5JFR A;  2Q94 A;  2GG0 A;  1N51 A;  2P9A A;  4R60 A;  2GG7 A;  4U6E A;  5CDE A;  2GA2 A;  4U6J A;  3BIT A;  5CIK A;  2BWV A;  1C24 A;  4IPA A;  1BOA A;  1R58 A;  3PKD A;  2B3K A;  2BHB A;  4RZZ A;  2MAT A;  2ZSG A;  2EVO A;  3CTZ A;  4FKC A;  2Q8K A;  1KQ0 A;  3Q6D A;  1XNZ A;  2P99 A;  5D6E A;  2Q93 A;  3CB6 A;  4FLK A;  2V6C A;  4IKT A;  1QXZ A;  2V3Z A;  3RVA A;  2EA4 A;  1W2M A;  1QZY A;  4FUK A;  4IKR A;  4JUQ A;  2GGB A;  2BB7 A;  2BWY A;  2HOW A;  4A6V A;  3BIP A;  2GTX A;  4RZY A;  4ZWO A;  3CB5 A;  1WL6 A;  2IW2 A;  2DFI A;  3FM3 A;  4S2R P;  2BWT A;  4FLL A;  4B28 A;  4Z7M A;  3IU9 A;  4IF7 A;  2BWW A;  2GG3 A;  3IU8 A;  4FLJ A;  2EVM A;  4U6W A;  1C27 A;  2GU5 A;  2V3Y A;  3MX6 A;  1XGS A;  4EGE A;  3IG4 A;  3PKE A;  4PV4 A;  2GG9 A;  1WN1 A;  3S6B A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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