3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Methionine aminopeptidase
publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
source organism Enterococcus faecalis
molecule tags Hydrolase
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
3D27A 4U76A 3CTZA 4EGEA 1WL6A 1WY2A 2V3XA 2BB7A 4OOKA 5CIKA 1QZYA 3FMQA 5CNXA 2BHBA 5CDVA 2BWWA 2IW2A 3FMRA 4U6CA 1A16A 1Y1NA 4S2RP 2DFIA 2GG7A 1C27A 3PKBA 4KM3A 1C24A 2GGBA 1YW8A 1YW9A 3CB5A 4JUQA 1WLRA 2GTXA 2G6PA 2EA4A 5FCFA 1N51A 4U75A 4IKRA 1YVMA 2HOWA 4R60A 2ZSGA 4U6JA 1QXWA 4Z7MA 2P99A 5E5BA 1MATA 1WBQA 4IKTA 2V6CA 2MATA 4S01A 4FLKA 1W2MA 2B3KA 2GZ5A 4ZWUA 4U1BA 4U6WA 3CB6A 2B3HA 3IU7A 2BWTA 3PKCA 4MATA 5CE6A 2GG9A 1C22A 2GG3A 3TB5A 4IPAA 2V3ZA 4FO8A 3L7GA 2GU7A 2BWXA 1KP0A 4IU6A 2P9AA 4ZNGA 4U73A 5JI6A 4IDYA 1R58A 3Q6DA 4ZWPA 4A6VA 2GG2A 4A6WA 1QXZA 1M35A 2BWUA 1XGSA 2ADUA 3BITA 1YW7A 3IG4A 3RORA 1CHMA 1KQ0A 2BH3A 2GA2A 2GG0A 3RVAA 2EVCA 4RGZ1 1C23A 2GG8A 2GU6A 2OKNA 2B3LA 5JHUA 3MATA 1PV9A 1JAWA 2V3YA 2OAZA 3PKDA 2BHCA 4FLIA 1WL9A 1B6AA 1WKMA 1C21A 1XGMA 3PKEA 2Q95A 4HXXA 2BWSA 4FO7A 5JFRA 4B28A 1B59A 4IKSA 4U69A 4ZWOA 4PV4A 4FUKA 4QR8A 5D6FA 4PNCA 3MX6A 1O0XA 1KQ9A 3S6BA 2GU5A 5FCHA 5CLSA 2Q94A 2Q92A 1R5HA 4IF7A 2NQ7A 2Q96A 5CDLA 2BHAA 1YJ3A 1BOAA 2GU4A 3PKAA 1XGNA 2BWVA 1WN1A 3TAVA 2EVOA 3L24A 3IU8A 1XNZA 3BIPA 2BWYA 1R5GA 2P98A 4RZZA 4U6EA 5D6EA 5CDEA 4IECA 4U6ZA 3IU9A 2EVMA 4U71A 1QXYA 1W7VA 1XGOA 2Q8KA 2GG5A 3BIQA 4FLJA 4S00A 4RZYA 1BN5A 4FKCA 4FLLA 3FM3A 3MR1A 2BN7A 2NQ6A 2BHDA 2EA2A 4S2TP 2GGCA 4U70A 4IKUA 2Q93A
chains in the Genus database with same CATH superfamily
3D27A 4U76A 3CTZA 4EGEA 1WL6A 1WY2A 2V3XA 2BB7A 4OOKA 5CIKA 1QZYA 3FMQA 5CNXA 2BHBA 5CDVA 2BWWA 2IW2A 3FMRA 4U6CA 1A16A 1Y1NA 4S2RP 2DFIA 2GG7A 1C27A 3PKBA 4KM3A 1C24A 2GGBA 1YW8A 1YW9A 3CB5A 4JUQA 1WLRA 2GTXA 2G6PA 2EA4A 5FCFA 1N51A 4U75A 4IKRA 1YVMA 2HOWA 4R60A 2ZSGA 4U6JA 1QXWA 4Z7MA 2P99A 5E5BA 1MATA 1WBQA 4IKTA 2V6CA 2MATA 4S01A 4FLKA 1W2MA 2B3KA 2GZ5A 4ZWUA 4U1BA 4U6WA 3CB6A 2B3HA 3IU7A 2BWTA 3PKCA 4MATA 5CE6A 2GG9A 1C22A 2GG3A 3TB5A 4IPAA 2V3ZA 4FO8A 3L7GA 2GU7A 2BWXA 1KP0A 4IU6A 2P9AA 4ZNGA 4U73A 5JI6A 4IDYA 1R58A 3Q6DA 4ZWPA 4A6VA 2GG2A 4A6WA 1QXZA 1M35A 2BWUA 1XGSA 2ADUA 3BITA 1YW7A 3IG4A 3RORA 1CHMA 1KQ0A 2BH3A 2GA2A 2GG0A 3RVAA 2EVCA 4RGZ1 1C23A 2GG8A 2GU6A 2OKNA 2B3LA 5JHUA 3MATA 1PV9A 1JAWA 2V3YA 2OAZA 3PKDA 2BHCA 4FLIA 1WL9A 1B6AA 1WKMA 1C21A 1XGMA 3PKEA 2Q95A 4HXXA 2BWSA 4FO7A 5JFRA 4B28A 1B59A 4IKSA 4U69A 4ZWOA 4PV4A 4FUKA 4QR8A 5D6FA 4PNCA 3MX6A 1O0XA 1KQ9A 3S6BA 2GU5A 5FCHA 5CLSA 2Q94A 2Q92A 1R5HA 4IF7A 2NQ7A 2Q96A 5CDLA 2BHAA 1YJ3A 1BOAA 2GU4A 3PKAA 1XGNA 2BWVA 1WN1A 3TAVA 2EVOA 3L24A 3IU8A 1XNZA 3BIPA 2BWYA 1R5GA 2P98A 4RZZA 4U6EA 5D6EA 5CDEA 4IECA 4U6ZA 3IU9A 2EVMA 4U71A 1QXYA 1W7VA 1XGOA 2Q8KA 2GG5A 3BIQA 4FLJA 4S00A 4RZYA 1BN5A 4FKCA 4FLLA 3FM3A 3MR1A 2BN7A 2NQ6A 2BHDA 2EA2A 4S2TP 2GGCA 4U70A 4IKUA 2Q93A
chains in the Genus database with same CATH topology
3D27A 4U76A 3CTZA 4EGEA 1WL6A 1WY2A 2V3XA 2BB7A 4OOKA 5CIKA 1QZYA 3FMQA 5CNXA 2BHBA 5CDVA 2BWWA 2IW2A 3FMRA 4U6CA 1A16A 1Y1NA 4S2RP 2DFIA 2GG7A 1C27A 3PKBA 4KM3A 1C24A 2GGBA 1YW8A 1YW9A 3CB5A 4JUQA 1WLRA 2GTXA 2G6PA 2EA4A 5FCFA 1N51A 4U75A 4IKRA 1YVMA 2HOWA 4R60A 2ZSGA 4U6JA 1QXWA 4Z7MA 2P99A 5E5BA 1MATA 1WBQA 4IKTA 2V6CA 2MATA 4S01A 4FLKA 1W2MA 2B3KA 2GZ5A 4ZWUA 4U1BA 4U6WA 3CB6A 2B3HA 3IU7A 2BWTA 3PKCA 4MATA 5CE6A 2GG9A 1C22A 2GG3A 3TB5A 4IPAA 2V3ZA 4FO8A 3L7GA 2GU7A 2BWXA 1KP0A 4IU6A 2P9AA 4ZNGA 4U73A 5JI6A 4IDYA 1R58A 3Q6DA 4ZWPA 4A6VA 2GG2A 4A6WA 1QXZA 1M35A 2BWUA 1XGSA 2ADUA 3BITA 1YW7A 3IG4A 3RORA 1CHMA 1KQ0A 2BH3A 2GA2A 2GG0A 3RVAA 2EVCA 4RGZ1 1C23A 2GG8A 2GU6A 2OKNA 2B3LA 5JHUA 3MATA 1PV9A 1JAWA 2V3YA 2OAZA 3PKDA 2BHCA 4FLIA 1WL9A 1B6AA 1WKMA 1C21A 1XGMA 3PKEA 2Q95A 4HXXA 2BWSA 4FO7A 5JFRA 4B28A 1B59A 4IKSA 4U69A 4ZWOA 4PV4A 4FUKA 4QR8A 5D6FA 4PNCA 3MX6A 1O0XA 1KQ9A 3S6BA 2GU5A 5FCHA 5CLSA 2Q94A 2Q92A 1R5HA 4IF7A 2NQ7A 2Q96A 5CDLA 2BHAA 1YJ3A 1BOAA 2GU4A 3PKAA 1XGNA 2BWVA 1WN1A 3TAVA 2EVOA 3L24A 3IU8A 1XNZA 3BIPA 2BWYA 1R5GA 2P98A 4RZZA 4U6EA 5D6EA 5CDEA 4IECA 4U6ZA 3IU9A 2EVMA 4U71A 1QXYA 1W7VA 1XGOA 2Q8KA 2GG5A 3BIQA 4FLJA 4S00A 4RZYA 1BN5A 4FKCA 4FLLA 3FM3A 3MR1A 2BN7A 2NQ6A 2BHDA 2EA2A 4S2TP 2GGCA 4U70A 4IKUA 2Q93A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3D27 A;  4U76 A;  3CTZ A;  4EGE A;  1WL6 A;  1WY2 A;  2V3X A;  2BB7 A;  4OOK A;  5CIK A;  1QZY A;  3FMQ A;  5CNX A;  2BHB A;  5CDV A;  2BWW A;  2IW2 A;  3FMR A;  4U6C A;  1A16 A;  1Y1N A;  4S2R P;  2DFI A;  2GG7 A;  1C27 A;  3PKB A;  4KM3 A;  1C24 A;  2GGB A;  1YW8 A;  1YW9 A;  3CB5 A;  4JUQ A;  1WLR A;  2GTX A;  2G6P A;  2EA4 A;  5FCF A;  1N51 A;  4U75 A;  4IKR A;  1YVM A;  2HOW A;  4R60 A;  2ZSG A;  4U6J A;  1QXW A;  4Z7M A;  2P99 A;  5E5B A;  1MAT A;  1WBQ A;  4IKT A;  2V6C A;  2MAT A;  4S01 A;  4FLK A;  1W2M A;  2B3K A;  2GZ5 A;  4ZWU A;  4U1B A;  4U6W A;  3CB6 A;  2B3H A;  3IU7 A;  2BWT A;  3PKC A;  4MAT A;  5CE6 A;  2GG9 A;  1C22 A;  2GG3 A;  3TB5 A;  4IPA A;  2V3Z A;  4FO8 A;  3L7G A;  2GU7 A;  2BWX A;  1KP0 A;  4IU6 A;  2P9A A;  4ZNG A;  4U73 A;  5JI6 A;  4IDY A;  1R58 A;  3Q6D A;  4ZWP A;  4A6V A;  2GG2 A;  4A6W A;  1QXZ A;  1M35 A;  2BWU A;  1XGS A;  2ADU A;  3BIT A;  1YW7 A;  3IG4 A;  3ROR A;  1CHM A;  1KQ0 A;  2BH3 A;  2GA2 A;  2GG0 A;  3RVA A;  2EVC A;  4RGZ 1;  1C23 A;  2GG8 A;  2GU6 A;  2OKN A;  2B3L A;  5JHU A;  3MAT A;  1PV9 A;  1JAW A;  2V3Y A;  2OAZ A;  3PKD A;  2BHC A;  4FLI A;  1WL9 A;  1B6A A;  1WKM A;  1C21 A;  1XGM A;  3PKE A;  2Q95 A;  4HXX A;  2BWS A;  4FO7 A;  5JFR A;  4B28 A;  1B59 A;  4IKS A;  4U69 A;  4ZWO A;  4PV4 A;  4FUK A;  4QR8 A;  5D6F A;  4PNC A;  3MX6 A;  1O0X A;  1KQ9 A;  3S6B A;  2GU5 A;  5FCH A;  5CLS A;  2Q94 A;  2Q92 A;  1R5H A;  4IF7 A;  2NQ7 A;  2Q96 A;  5CDL A;  2BHA A;  1YJ3 A;  1BOA A;  2GU4 A;  3PKA A;  1XGN A;  2BWV A;  1WN1 A;  3TAV A;  2EVO A;  3L24 A;  3IU8 A;  1XNZ A;  3BIP A;  2BWY A;  1R5G A;  2P98 A;  4RZZ A;  4U6E A;  5D6E A;  5CDE A;  4IEC A;  4U6Z A;  3IU9 A;  2EVM A;  4U71 A;  1QXY A;  1W7V A;  1XGO A;  2Q8K A;  2GG5 A;  3BIQ A;  4FLJ A;  4S00 A;  4RZY A;  1BN5 A;  4FKC A;  4FLL A;  3FM3 A;  3MR1 A;  2BN7 A;  2NQ6 A;  2BHD A;  2EA2 A;  4S2T P;  2GGC A;  4U70 A;  4IKU A;  2Q93 A; 
#chains in the Genus database with same CATH topology
 3D27 A;  4U76 A;  3CTZ A;  4EGE A;  1WL6 A;  1WY2 A;  2V3X A;  2BB7 A;  4OOK A;  5CIK A;  1QZY A;  3FMQ A;  5CNX A;  2BHB A;  5CDV A;  2BWW A;  2IW2 A;  3FMR A;  4U6C A;  1A16 A;  1Y1N A;  4S2R P;  2DFI A;  2GG7 A;  1C27 A;  3PKB A;  4KM3 A;  1C24 A;  2GGB A;  1YW8 A;  1YW9 A;  3CB5 A;  4JUQ A;  1WLR A;  2GTX A;  2G6P A;  2EA4 A;  5FCF A;  1N51 A;  4U75 A;  4IKR A;  1YVM A;  2HOW A;  4R60 A;  2ZSG A;  4U6J A;  1QXW A;  4Z7M A;  2P99 A;  5E5B A;  1MAT A;  1WBQ A;  4IKT A;  2V6C A;  2MAT A;  4S01 A;  4FLK A;  1W2M A;  2B3K A;  2GZ5 A;  4ZWU A;  4U1B A;  4U6W A;  3CB6 A;  2B3H A;  3IU7 A;  2BWT A;  3PKC A;  4MAT A;  5CE6 A;  2GG9 A;  1C22 A;  2GG3 A;  3TB5 A;  4IPA A;  2V3Z A;  4FO8 A;  3L7G A;  2GU7 A;  2BWX A;  1KP0 A;  4IU6 A;  2P9A A;  4ZNG A;  4U73 A;  5JI6 A;  4IDY A;  1R58 A;  3Q6D A;  4ZWP A;  4A6V A;  2GG2 A;  4A6W A;  1QXZ A;  1M35 A;  2BWU A;  1XGS A;  2ADU A;  3BIT A;  1YW7 A;  3IG4 A;  3ROR A;  1CHM A;  1KQ0 A;  2BH3 A;  2GA2 A;  2GG0 A;  3RVA A;  2EVC A;  4RGZ 1;  1C23 A;  2GG8 A;  2GU6 A;  2OKN A;  2B3L A;  5JHU A;  3MAT A;  1PV9 A;  1JAW A;  2V3Y A;  2OAZ A;  3PKD A;  2BHC A;  4FLI A;  1WL9 A;  1B6A A;  1WKM A;  1C21 A;  1XGM A;  3PKE A;  2Q95 A;  4HXX A;  2BWS A;  4FO7 A;  5JFR A;  4B28 A;  1B59 A;  4IKS A;  4U69 A;  4ZWO A;  4PV4 A;  4FUK A;  4QR8 A;  5D6F A;  4PNC A;  3MX6 A;  1O0X A;  1KQ9 A;  3S6B A;  2GU5 A;  5FCH A;  5CLS A;  2Q94 A;  2Q92 A;  1R5H A;  4IF7 A;  2NQ7 A;  2Q96 A;  5CDL A;  2BHA A;  1YJ3 A;  1BOA A;  2GU4 A;  3PKA A;  1XGN A;  2BWV A;  1WN1 A;  3TAV A;  2EVO A;  3L24 A;  3IU8 A;  1XNZ A;  3BIP A;  2BWY A;  1R5G A;  2P98 A;  4RZZ A;  4U6E A;  5D6E A;  5CDE A;  4IEC A;  4U6Z A;  3IU9 A;  2EVM A;  4U71 A;  1QXY A;  1W7V A;  1XGO A;  2Q8K A;  2GG5 A;  3BIQ A;  4FLJ A;  4S00 A;  4RZY A;  1BN5 A;  4FKC A;  4FLL A;  3FM3 A;  3MR1 A;  2BN7 A;  2NQ6 A;  2BHD A;  2EA2 A;  4S2T P;  2GGC A;  4U70 A;  4IKU A;  2Q93 A; 
#chains in the Genus database with same CATH homology
 3D27 A;  4U76 A;  3CTZ A;  4EGE A;  1WL6 A;  1WY2 A;  2V3X A;  2BB7 A;  4OOK A;  5CIK A;  1QZY A;  3FMQ A;  5CNX A;  2BHB A;  5CDV A;  2BWW A;  2IW2 A;  3FMR A;  4U6C A;  1A16 A;  1Y1N A;  4S2R P;  2DFI A;  2GG7 A;  1C27 A;  3PKB A;  4KM3 A;  1C24 A;  2GGB A;  1YW8 A;  1YW9 A;  3CB5 A;  4JUQ A;  1WLR A;  2GTX A;  2G6P A;  2EA4 A;  5FCF A;  1N51 A;  4U75 A;  4IKR A;  1YVM A;  2HOW A;  4R60 A;  2ZSG A;  4U6J A;  1QXW A;  4Z7M A;  2P99 A;  5E5B A;  1MAT A;  1WBQ A;  4IKT A;  2V6C A;  2MAT A;  4S01 A;  4FLK A;  1W2M A;  2B3K A;  2GZ5 A;  4ZWU A;  4U1B A;  4U6W A;  3CB6 A;  2B3H A;  3IU7 A;  2BWT A;  3PKC A;  4MAT A;  5CE6 A;  2GG9 A;  1C22 A;  2GG3 A;  3TB5 A;  4IPA A;  2V3Z A;  4FO8 A;  3L7G A;  2GU7 A;  2BWX A;  1KP0 A;  4IU6 A;  2P9A A;  4ZNG A;  4U73 A;  5JI6 A;  4IDY A;  1R58 A;  3Q6D A;  4ZWP A;  4A6V A;  2GG2 A;  4A6W A;  1QXZ A;  1M35 A;  2BWU A;  1XGS A;  2ADU A;  3BIT A;  1YW7 A;  3IG4 A;  3ROR A;  1CHM A;  1KQ0 A;  2BH3 A;  2GA2 A;  2GG0 A;  3RVA A;  2EVC A;  4RGZ 1;  1C23 A;  2GG8 A;  2GU6 A;  2OKN A;  2B3L A;  5JHU A;  3MAT A;  1PV9 A;  1JAW A;  2V3Y A;  2OAZ A;  3PKD A;  2BHC A;  4FLI A;  1WL9 A;  1B6A A;  1WKM A;  1C21 A;  1XGM A;  3PKE A;  2Q95 A;  4HXX A;  2BWS A;  4FO7 A;  5JFR A;  4B28 A;  1B59 A;  4IKS A;  4U69 A;  4ZWO A;  4PV4 A;  4FUK A;  4QR8 A;  5D6F A;  4PNC A;  3MX6 A;  1O0X A;  1KQ9 A;  3S6B A;  2GU5 A;  5FCH A;  5CLS A;  2Q94 A;  2Q92 A;  1R5H A;  4IF7 A;  2NQ7 A;  2Q96 A;  5CDL A;  2BHA A;  1YJ3 A;  1BOA A;  2GU4 A;  3PKA A;  1XGN A;  2BWV A;  1WN1 A;  3TAV A;  2EVO A;  3L24 A;  3IU8 A;  1XNZ A;  3BIP A;  2BWY A;  1R5G A;  2P98 A;  4RZZ A;  4U6E A;  5D6E A;  5CDE A;  4IEC A;  4U6Z A;  3IU9 A;  2EVM A;  4U71 A;  1QXY A;  1W7V A;  1XGO A;  2Q8K A;  2GG5 A;  3BIQ A;  4FLJ A;  4S00 A;  4RZY A;  1BN5 A;  4FKC A;  4FLL A;  3FM3 A;  3MR1 A;  2BN7 A;  2NQ6 A;  2BHD A;  2EA2 A;  4S2T P;  2GGC A;  4U70 A;  4IKU A;  2Q93 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...