3TB5A

Crystal structure of the enterococcus faecalis methionine aminopeptidase apo form
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
254
structure length
254
Chain Sequence
MITLKSPREIEMMDESGELLADVHRHLRTFIKPGITSWDIEVFVRDFIESHGGVAAQIGYEGYKYATCCSINDEICHGFPRKKVLKDGDLIKVDMCVDLKGAISDSCWSYVVGESTPEIDRLMEVTKKALYLGIEQAQVGNRIGDIGHAIQTYVEGEGYGVVRDFVGHGIGPTIHESPMIPHYGEAGKGLRLKEGMVITIEPMVNTGTWRMKMDPNGWTAYTEDGGLSCQYEHSLAITKEGPRILTSQGEELTY
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Structural studies of Enterococcus faecalis methionine aminopeptidase and design of microbe specific 2,2'-bipyridine based inhibitors
doi rcsb
source organism Enterococcus faecalis
molecule tags Hydrolase
total genus 87
structure length 254
sequence length 254
chains with identical sequence B, C
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-08-05
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3tb5A00
1BOAA 2MATA 4S00A 1PV9A 2GU7A 1QXYA 2V6CA 4FLLA 2GG3A 4U6JA 3IG4A 4FO7A 2BWWA 4Z7MA 2NQ7A 5JFRA 2BWTA 3MX6A 2BWUA 1C24A 2Q94A 5FCFA 3FMQA 4IDYA 5JHUA 4S2TP 3PKCA 3PKAA 4U69A 1WBQA 2ZSGA 1XGNA 3L7GA 3PKBA 4U71A 5D6FA 4IKUA 1A16A 3L24A 4U75A 1XGOA 5CLSA 5CE6A 5FCHA 2EVMA 4S2RP 1XNZA 4IKRA 3IU8A 3PKDA 4FO8A 2GA2A 4U70A 1QXZA 2V3ZA 2OKNA 3IU7A 5E5BA 1XGMA 3S6BA 2GU6A 1MATA 1YW8A 1YJ3A 2Q93A 4RZZA 2EA4A 4ZWOA 3TAVA 1YW9A 2Q96A 5CDVA 1CHMA 4IPAA 4U6EA 1KQ9A 1WY2A 2DFIA 1XGSA 2GGBA 4EGEA 4U6WA 2BHBA 3BIQA 1R5HA 2GTXA 3FM3A 1W7VA 4FKCA 4IKSA 4ZWUA 5CDLA 4ZWPA 1M35A 2ADUA 4FLKA 2Q95A 2BN7A 2BHDA 1B59A 3BIPA 4RGZ1 4FLJA 3Q6DA 1BN5A 1Y1NA 1R58A 2IW2A 3RVAA 2NQ6A 4HXXA 4RZYA 2BWXA 1C23A 2GG8A 2GGCA 1JAWA 4IF7A 4A6VA 4A6WA 5CDEA 2GG2A 4IECA 3FMRA 5JI6A 1WL6A 1WL9A 4U76A 4MATA 3MATA 3MR1A 2G6PA 2B3LA 4ZNGA 3CTZA 4U1BA 1YVMA 3BITA 4IKTA 1O0XA 2B3HA 3RORA 4IU6A 1C22A 2EVOA 3D27A 1WN1A 3PKEA 1KP0A 4FUKA 4S01A 1C27A 2EVCA 4OOKA 4PNCA 1YW7A 2BHCA 1WKMA 2V3XA 1KQ0A 2GU4A 2EA2A 2GG9A 2V3YA 4R60A 2P99A 4JUQA 5D6EA 5CNXA 3IU9A 2BB7A 1WLRA 4U6ZA 2BHAA 1N51A 4QR8A 2OAZA 4U6CA 2GU5A 1QXWA 2B3KA 4KM3A 4PV4A 5CIKA 2P98A 4FLIA 3CB6A 2GG0A 2P9AA 1QZYA 2BWVA 1B6AA 1C21A 4B28A 1W2MA 2Q8KA 3CB5A 2BWSA 2Q92A 2GZ5A 4U73A 2GG7A 1R5GA 2HOWA 2BH3A 2BWYA 3TB5A 2GG5A
chains in the Genus database with same CATH superfamily
1BOAA 2MATA 4S00A 1PV9A 2GU7A 1QXYA 2V6CA 4FLLA 2GG3A 4U6JA 3IG4A 4FO7A 2BWWA 4Z7MA 2NQ7A 5JFRA 2BWTA 3MX6A 2BWUA 1C24A 2Q94A 5FCFA 3FMQA 4IDYA 5JHUA 4S2TP 3PKCA 3PKAA 4U69A 1WBQA 2ZSGA 1XGNA 3L7GA 3PKBA 4U71A 5D6FA 4IKUA 1A16A 3L24A 4U75A 1XGOA 5CLSA 5CE6A 5FCHA 2EVMA 4S2RP 1XNZA 4IKRA 3IU8A 3PKDA 4FO8A 2GA2A 4U70A 1QXZA 2V3ZA 2OKNA 3IU7A 5E5BA 1XGMA 3S6BA 2GU6A 1MATA 1YW8A 1YJ3A 2Q93A 4RZZA 2EA4A 4ZWOA 3TAVA 1YW9A 2Q96A 5CDVA 1CHMA 4IPAA 4U6EA 1KQ9A 1WY2A 2DFIA 1XGSA 2GGBA 4EGEA 4U6WA 2BHBA 3BIQA 1R5HA 2GTXA 3FM3A 1W7VA 4FKCA 4IKSA 4ZWUA 5CDLA 4ZWPA 1M35A 2ADUA 4FLKA 2Q95A 2BN7A 2BHDA 1B59A 3BIPA 4RGZ1 4FLJA 3Q6DA 1BN5A 1Y1NA 1R58A 2IW2A 3RVAA 2NQ6A 4HXXA 4RZYA 2BWXA 1C23A 2GG8A 2GGCA 1JAWA 4IF7A 4A6VA 4A6WA 5CDEA 2GG2A 4IECA 3FMRA 5JI6A 1WL6A 1WL9A 4U76A 4MATA 3MATA 3MR1A 2G6PA 2B3LA 4ZNGA 3CTZA 4U1BA 1YVMA 3BITA 4IKTA 1O0XA 2B3HA 3RORA 4IU6A 1C22A 2EVOA 3D27A 1WN1A 3PKEA 1KP0A 4FUKA 4S01A 1C27A 2EVCA 4OOKA 4PNCA 1YW7A 2BHCA 1WKMA 2V3XA 1KQ0A 2GU4A 2EA2A 2GG9A 2V3YA 4R60A 2P99A 4JUQA 5D6EA 5CNXA 3IU9A 2BB7A 1WLRA 4U6ZA 2BHAA 1N51A 4QR8A 2OAZA 4U6CA 2GU5A 1QXWA 2B3KA 4KM3A 4PV4A 5CIKA 2P98A 4FLIA 3CB6A 2GG0A 2P9AA 1QZYA 2BWVA 1B6AA 1C21A 4B28A 1W2MA 2Q8KA 3CB5A 2BWSA 2Q92A 2GZ5A 4U73A 2GG7A 1R5GA 2HOWA 2BH3A 2BWYA 3TB5A 2GG5A
chains in the Genus database with same CATH topology
1BOAA 2MATA 4S00A 1PV9A 2GU7A 1QXYA 2V6CA 4FLLA 2GG3A 4U6JA 3IG4A 4FO7A 2BWWA 4Z7MA 2NQ7A 5JFRA 2BWTA 3MX6A 2BWUA 1C24A 2Q94A 5FCFA 3FMQA 4IDYA 5JHUA 4S2TP 3PKCA 3PKAA 4U69A 1WBQA 2ZSGA 1XGNA 3L7GA 3PKBA 4U71A 5D6FA 4IKUA 1A16A 3L24A 4U75A 1XGOA 5CLSA 5CE6A 5FCHA 2EVMA 4S2RP 1XNZA 4IKRA 3IU8A 3PKDA 4FO8A 2GA2A 4U70A 1QXZA 2V3ZA 2OKNA 3IU7A 5E5BA 1XGMA 3S6BA 2GU6A 1MATA 1YW8A 1YJ3A 2Q93A 4RZZA 2EA4A 4ZWOA 3TAVA 1YW9A 2Q96A 5CDVA 1CHMA 4IPAA 4U6EA 1KQ9A 1WY2A 2DFIA 1XGSA 2GGBA 4EGEA 4U6WA 2BHBA 3BIQA 1R5HA 2GTXA 3FM3A 1W7VA 4FKCA 4IKSA 4ZWUA 5CDLA 4ZWPA 1M35A 2ADUA 4FLKA 2Q95A 2BN7A 2BHDA 1B59A 3BIPA 4RGZ1 4FLJA 3Q6DA 1BN5A 1Y1NA 1R58A 2IW2A 3RVAA 2NQ6A 4HXXA 4RZYA 2BWXA 1C23A 2GG8A 2GGCA 1JAWA 4IF7A 4A6VA 4A6WA 5CDEA 2GG2A 4IECA 3FMRA 5JI6A 1WL6A 1WL9A 4U76A 4MATA 3MATA 3MR1A 2G6PA 2B3LA 4ZNGA 3CTZA 4U1BA 1YVMA 3BITA 4IKTA 1O0XA 2B3HA 3RORA 4IU6A 1C22A 2EVOA 3D27A 1WN1A 3PKEA 1KP0A 4FUKA 4S01A 1C27A 2EVCA 4OOKA 4PNCA 1YW7A 2BHCA 1WKMA 2V3XA 1KQ0A 2GU4A 2EA2A 2GG9A 2V3YA 4R60A 2P99A 4JUQA 5D6EA 5CNXA 3IU9A 2BB7A 1WLRA 4U6ZA 2BHAA 1N51A 4QR8A 2OAZA 4U6CA 2GU5A 1QXWA 2B3KA 4KM3A 4PV4A 5CIKA 2P98A 4FLIA 3CB6A 2GG0A 2P9AA 1QZYA 2BWVA 1B6AA 1C21A 4B28A 1W2MA 2Q8KA 3CB5A 2BWSA 2Q92A 2GZ5A 4U73A 2GG7A 1R5GA 2HOWA 2BH3A 2BWYA 3TB5A 2GG5A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1BOA A;  2MAT A;  4S00 A;  1PV9 A;  2GU7 A;  1QXY A;  2V6C A;  4FLL A;  2GG3 A;  4U6J A;  3IG4 A;  4FO7 A;  2BWW A;  4Z7M A;  2NQ7 A;  5JFR A;  2BWT A;  3MX6 A;  2BWU A;  1C24 A;  2Q94 A;  5FCF A;  3FMQ A;  4IDY A;  5JHU A;  4S2T P;  3PKC A;  3PKA A;  4U69 A;  1WBQ A;  2ZSG A;  1XGN A;  3L7G A;  3PKB A;  4U71 A;  5D6F A;  4IKU A;  1A16 A;  3L24 A;  4U75 A;  1XGO A;  5CLS A;  5CE6 A;  5FCH A;  2EVM A;  4S2R P;  1XNZ A;  4IKR A;  3IU8 A;  3PKD A;  4FO8 A;  2GA2 A;  4U70 A;  1QXZ A;  2V3Z A;  2OKN A;  3IU7 A;  5E5B A;  1XGM A;  3S6B A;  2GU6 A;  1MAT A;  1YW8 A;  1YJ3 A;  2Q93 A;  4RZZ A;  2EA4 A;  4ZWO A;  3TAV A;  1YW9 A;  2Q96 A;  5CDV A;  1CHM A;  4IPA A;  4U6E A;  1KQ9 A;  1WY2 A;  2DFI A;  1XGS A;  2GGB A;  4EGE A;  4U6W A;  2BHB A;  3BIQ A;  1R5H A;  2GTX A;  3FM3 A;  1W7V A;  4FKC A;  4IKS A;  4ZWU A;  5CDL A;  4ZWP A;  1M35 A;  2ADU A;  4FLK A;  2Q95 A;  2BN7 A;  2BHD A;  1B59 A;  3BIP A;  4RGZ 1;  4FLJ A;  3Q6D A;  1BN5 A;  1Y1N A;  1R58 A;  2IW2 A;  3RVA A;  2NQ6 A;  4HXX A;  4RZY A;  2BWX A;  1C23 A;  2GG8 A;  2GGC A;  1JAW A;  4IF7 A;  4A6V A;  4A6W A;  5CDE A;  2GG2 A;  4IEC A;  3FMR A;  5JI6 A;  1WL6 A;  1WL9 A;  4U76 A;  4MAT A;  3MAT A;  3MR1 A;  2G6P A;  2B3L A;  4ZNG A;  3CTZ A;  4U1B A;  1YVM A;  3BIT A;  4IKT A;  1O0X A;  2B3H A;  3ROR A;  4IU6 A;  1C22 A;  2EVO A;  3D27 A;  1WN1 A;  3PKE A;  1KP0 A;  4FUK A;  4S01 A;  1C27 A;  2EVC A;  4OOK A;  4PNC A;  1YW7 A;  2BHC A;  1WKM A;  2V3X A;  1KQ0 A;  2GU4 A;  2EA2 A;  2GG9 A;  2V3Y A;  4R60 A;  2P99 A;  4JUQ A;  5D6E A;  5CNX A;  3IU9 A;  2BB7 A;  1WLR A;  4U6Z A;  2BHA A;  1N51 A;  4QR8 A;  2OAZ A;  4U6C A;  2GU5 A;  1QXW A;  2B3K A;  4KM3 A;  4PV4 A;  5CIK A;  2P98 A;  4FLI A;  3CB6 A;  2GG0 A;  2P9A A;  1QZY A;  2BWV A;  1B6A A;  1C21 A;  4B28 A;  1W2M A;  2Q8K A;  3CB5 A;  2BWS A;  2Q92 A;  2GZ5 A;  4U73 A;  2GG7 A;  1R5G A;  2HOW A;  2BH3 A;  2BWY A;  3TB5 A;  2GG5 A; 
#chains in the Genus database with same CATH topology
 1BOA A;  2MAT A;  4S00 A;  1PV9 A;  2GU7 A;  1QXY A;  2V6C A;  4FLL A;  2GG3 A;  4U6J A;  3IG4 A;  4FO7 A;  2BWW A;  4Z7M A;  2NQ7 A;  5JFR A;  2BWT A;  3MX6 A;  2BWU A;  1C24 A;  2Q94 A;  5FCF A;  3FMQ A;  4IDY A;  5JHU A;  4S2T P;  3PKC A;  3PKA A;  4U69 A;  1WBQ A;  2ZSG A;  1XGN A;  3L7G A;  3PKB A;  4U71 A;  5D6F A;  4IKU A;  1A16 A;  3L24 A;  4U75 A;  1XGO A;  5CLS A;  5CE6 A;  5FCH A;  2EVM A;  4S2R P;  1XNZ A;  4IKR A;  3IU8 A;  3PKD A;  4FO8 A;  2GA2 A;  4U70 A;  1QXZ A;  2V3Z A;  2OKN A;  3IU7 A;  5E5B A;  1XGM A;  3S6B A;  2GU6 A;  1MAT A;  1YW8 A;  1YJ3 A;  2Q93 A;  4RZZ A;  2EA4 A;  4ZWO A;  3TAV A;  1YW9 A;  2Q96 A;  5CDV A;  1CHM A;  4IPA A;  4U6E A;  1KQ9 A;  1WY2 A;  2DFI A;  1XGS A;  2GGB A;  4EGE A;  4U6W A;  2BHB A;  3BIQ A;  1R5H A;  2GTX A;  3FM3 A;  1W7V A;  4FKC A;  4IKS A;  4ZWU A;  5CDL A;  4ZWP A;  1M35 A;  2ADU A;  4FLK A;  2Q95 A;  2BN7 A;  2BHD A;  1B59 A;  3BIP A;  4RGZ 1;  4FLJ A;  3Q6D A;  1BN5 A;  1Y1N A;  1R58 A;  2IW2 A;  3RVA A;  2NQ6 A;  4HXX A;  4RZY A;  2BWX A;  1C23 A;  2GG8 A;  2GGC A;  1JAW A;  4IF7 A;  4A6V A;  4A6W A;  5CDE A;  2GG2 A;  4IEC A;  3FMR A;  5JI6 A;  1WL6 A;  1WL9 A;  4U76 A;  4MAT A;  3MAT A;  3MR1 A;  2G6P A;  2B3L A;  4ZNG A;  3CTZ A;  4U1B A;  1YVM A;  3BIT A;  4IKT A;  1O0X A;  2B3H A;  3ROR A;  4IU6 A;  1C22 A;  2EVO A;  3D27 A;  1WN1 A;  3PKE A;  1KP0 A;  4FUK A;  4S01 A;  1C27 A;  2EVC A;  4OOK A;  4PNC A;  1YW7 A;  2BHC A;  1WKM A;  2V3X A;  1KQ0 A;  2GU4 A;  2EA2 A;  2GG9 A;  2V3Y A;  4R60 A;  2P99 A;  4JUQ A;  5D6E A;  5CNX A;  3IU9 A;  2BB7 A;  1WLR A;  4U6Z A;  2BHA A;  1N51 A;  4QR8 A;  2OAZ A;  4U6C A;  2GU5 A;  1QXW A;  2B3K A;  4KM3 A;  4PV4 A;  5CIK A;  2P98 A;  4FLI A;  3CB6 A;  2GG0 A;  2P9A A;  1QZY A;  2BWV A;  1B6A A;  1C21 A;  4B28 A;  1W2M A;  2Q8K A;  3CB5 A;  2BWS A;  2Q92 A;  2GZ5 A;  4U73 A;  2GG7 A;  1R5G A;  2HOW A;  2BH3 A;  2BWY A;  3TB5 A;  2GG5 A; 
#chains in the Genus database with same CATH homology
 1BOA A;  2MAT A;  4S00 A;  1PV9 A;  2GU7 A;  1QXY A;  2V6C A;  4FLL A;  2GG3 A;  4U6J A;  3IG4 A;  4FO7 A;  2BWW A;  4Z7M A;  2NQ7 A;  5JFR A;  2BWT A;  3MX6 A;  2BWU A;  1C24 A;  2Q94 A;  5FCF A;  3FMQ A;  4IDY A;  5JHU A;  4S2T P;  3PKC A;  3PKA A;  4U69 A;  1WBQ A;  2ZSG A;  1XGN A;  3L7G A;  3PKB A;  4U71 A;  5D6F A;  4IKU A;  1A16 A;  3L24 A;  4U75 A;  1XGO A;  5CLS A;  5CE6 A;  5FCH A;  2EVM A;  4S2R P;  1XNZ A;  4IKR A;  3IU8 A;  3PKD A;  4FO8 A;  2GA2 A;  4U70 A;  1QXZ A;  2V3Z A;  2OKN A;  3IU7 A;  5E5B A;  1XGM A;  3S6B A;  2GU6 A;  1MAT A;  1YW8 A;  1YJ3 A;  2Q93 A;  4RZZ A;  2EA4 A;  4ZWO A;  3TAV A;  1YW9 A;  2Q96 A;  5CDV A;  1CHM A;  4IPA A;  4U6E A;  1KQ9 A;  1WY2 A;  2DFI A;  1XGS A;  2GGB A;  4EGE A;  4U6W A;  2BHB A;  3BIQ A;  1R5H A;  2GTX A;  3FM3 A;  1W7V A;  4FKC A;  4IKS A;  4ZWU A;  5CDL A;  4ZWP A;  1M35 A;  2ADU A;  4FLK A;  2Q95 A;  2BN7 A;  2BHD A;  1B59 A;  3BIP A;  4RGZ 1;  4FLJ A;  3Q6D A;  1BN5 A;  1Y1N A;  1R58 A;  2IW2 A;  3RVA A;  2NQ6 A;  4HXX A;  4RZY A;  2BWX A;  1C23 A;  2GG8 A;  2GGC A;  1JAW A;  4IF7 A;  4A6V A;  4A6W A;  5CDE A;  2GG2 A;  4IEC A;  3FMR A;  5JI6 A;  1WL6 A;  1WL9 A;  4U76 A;  4MAT A;  3MAT A;  3MR1 A;  2G6P A;  2B3L A;  4ZNG A;  3CTZ A;  4U1B A;  1YVM A;  3BIT A;  4IKT A;  1O0X A;  2B3H A;  3ROR A;  4IU6 A;  1C22 A;  2EVO A;  3D27 A;  1WN1 A;  3PKE A;  1KP0 A;  4FUK A;  4S01 A;  1C27 A;  2EVC A;  4OOK A;  4PNC A;  1YW7 A;  2BHC A;  1WKM A;  2V3X A;  1KQ0 A;  2GU4 A;  2EA2 A;  2GG9 A;  2V3Y A;  4R60 A;  2P99 A;  4JUQ A;  5D6E A;  5CNX A;  3IU9 A;  2BB7 A;  1WLR A;  4U6Z A;  2BHA A;  1N51 A;  4QR8 A;  2OAZ A;  4U6C A;  2GU5 A;  1QXW A;  2B3K A;  4KM3 A;  4PV4 A;  5CIK A;  2P98 A;  4FLI A;  3CB6 A;  2GG0 A;  2P9A A;  1QZY A;  2BWV A;  1B6A A;  1C21 A;  4B28 A;  1W2M A;  2Q8K A;  3CB5 A;  2BWS A;  2Q92 A;  2GZ5 A;  4U73 A;  2GG7 A;  1R5G A;  2HOW A;  2BH3 A;  2BWY A;  3TB5 A;  2GG5 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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