4A6WA

X-ray structures of oxazole hydroxamate ecmetap-mn complexes
Total Genus 83
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
83
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Transferase
publication title Hydroxamic Acids as Potent Inhibitors of Fe(II) and Mn(II) E. Coli Methionine Aminopeptidase: Biological Activities and X-Ray Structures of Oxazole Hydroxamate-Ecmetap-Mn Complexes.
pubmed doi rcsb
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 83
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2011-11-09

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4a6wA00
4IKSA 1N51A 2EVMA 2BB7A 4B28A 3CB6A 4IECA 3CTZA 2GG2A 1WBQA 3BITA 2DFIA 2V6CA 4FUKA 1XGOA 4FO8A 1B59A 2BWTA 1QXYA 2V3YA 2GGCA 2BH3A 1YW7A 5FCHA 2BWVA 4MATA 2Q94A 4KM3A 3Q6DA 4EGEA 5CNXA 4IKUA 3PKEA 4ZWOA 1C24A 1W7VA 3IU7A 4S00A 2BHBA 4A6WA 2EVOA 1B6AA 4U6JA 4HXXA 5CE6A 2GU4A 3TAVA 1C22A 4FO7A 5CIKA 2BWSA 1KQ0A 3L24A 1XGMA 1KQ9A 1MATA 1WKMA 1JAWA 5CDEA 2G6PA 1R5GA 4RZZA 3CB5A 4IPAA 4FLKA 4QR8A 3PKCA 1C21A 2NQ7A 2Q96A 1YW9A 2GG3A 1QXZA 2OAZA 2BHDA 2BN7A 3PKBA 4ZWUA 4RGZ1 1KP0A 4PNCA 5D6EA 2Q92A 4IKRA 4U70A 2Q93A 2BWXA 1W2MA 2Q95A 5FCFA 1R58A 4U6CA 1BN5A 3D27A 2V3ZA 4S2TP 2ADUA 2BHAA 2HOWA 3FMQA 3BIPA 2GG0A 1Y1NA 3BIQA 2BHCA 4U6WA 1WL9A 4U73A 2Q8KA 4Z7MA 3TB5A 4U6ZA 4FKCA 2P99A 5D6FA 5JHUA 3MATA 2P9AA 4U71A 3S6BA 1O0XA 1QXWA 4U76A 1WN1A 2GU6A 1WY2A 5CLSA 3L7GA 4R60A 4ZWPA 4PV4A 4IU6A 2B3LA 2V3XA 2BWYA 4ZNGA 2GG8A 1BOAA 1YVMA 3FMRA 1PV9A 3MR1A 2B3HA 4S01A 5CDVA 2GG7A 3MX6A 4FLLA 3RVAA 3PKDA 3IU9A 4U75A 2GA2A 2GTXA 2EA2A 5E5BA 1XGSA 1A16A 4JUQA 4FLJA 2GU7A 2EA4A 2NQ6A 4U69A 1QZYA 2B3KA 2GGBA 5CDLA 4U6EA 4IF7A 2BWWA 2OKNA 2P98A 4RZYA 1XNZA 3IU8A 4U1BA 1CHMA 2EVCA 5JFRA 2IW2A 1WLRA 3RORA 1M35A 4S2RP 2GG5A 3FM3A 5JI6A 1C23A 2ZSGA 2MATA 1R5HA 1XGNA 2GU5A 4OOKA 2GG9A 4IKTA 1YJ3A 1YW8A 1WL6A 3IG4A 1C27A 2GZ5A 2BWUA 4IDYA 4FLIA 4A6VA 3PKAA
chains in the Genus database with same CATH superfamily
4IKSA 1N51A 2EVMA 2BB7A 4B28A 3CB6A 4IECA 3CTZA 2GG2A 1WBQA 3BITA 2DFIA 2V6CA 4FUKA 1XGOA 4FO8A 1B59A 2BWTA 1QXYA 2V3YA 2GGCA 2BH3A 1YW7A 5FCHA 2BWVA 4MATA 2Q94A 4KM3A 3Q6DA 4EGEA 5CNXA 4IKUA 3PKEA 4ZWOA 1C24A 1W7VA 3IU7A 4S00A 2BHBA 4A6WA 2EVOA 1B6AA 4U6JA 4HXXA 5CE6A 2GU4A 3TAVA 1C22A 4FO7A 5CIKA 2BWSA 1KQ0A 3L24A 1XGMA 1KQ9A 1MATA 1WKMA 1JAWA 5CDEA 2G6PA 1R5GA 4RZZA 3CB5A 4IPAA 4FLKA 4QR8A 3PKCA 1C21A 2NQ7A 2Q96A 1YW9A 2GG3A 1QXZA 2OAZA 2BHDA 2BN7A 3PKBA 4ZWUA 4RGZ1 1KP0A 4PNCA 5D6EA 2Q92A 4IKRA 4U70A 2Q93A 2BWXA 1W2MA 2Q95A 5FCFA 1R58A 4U6CA 1BN5A 3D27A 2V3ZA 4S2TP 2ADUA 2BHAA 2HOWA 3FMQA 3BIPA 2GG0A 1Y1NA 3BIQA 2BHCA 4U6WA 1WL9A 4U73A 2Q8KA 4Z7MA 3TB5A 4U6ZA 4FKCA 2P99A 5D6FA 5JHUA 3MATA 2P9AA 4U71A 3S6BA 1O0XA 1QXWA 4U76A 1WN1A 2GU6A 1WY2A 5CLSA 3L7GA 4R60A 4ZWPA 4PV4A 4IU6A 2B3LA 2V3XA 2BWYA 4ZNGA 2GG8A 1BOAA 1YVMA 3FMRA 1PV9A 3MR1A 2B3HA 4S01A 5CDVA 2GG7A 3MX6A 4FLLA 3RVAA 3PKDA 3IU9A 4U75A 2GA2A 2GTXA 2EA2A 5E5BA 1XGSA 1A16A 4JUQA 4FLJA 2GU7A 2EA4A 2NQ6A 4U69A 1QZYA 2B3KA 2GGBA 5CDLA 4U6EA 4IF7A 2BWWA 2OKNA 2P98A 4RZYA 1XNZA 3IU8A 4U1BA 1CHMA 2EVCA 5JFRA 2IW2A 1WLRA 3RORA 1M35A 4S2RP 2GG5A 3FM3A 5JI6A 1C23A 2ZSGA 2MATA 1R5HA 1XGNA 2GU5A 4OOKA 2GG9A 4IKTA 1YJ3A 1YW8A 1WL6A 3IG4A 1C27A 2GZ5A 2BWUA 4IDYA 4FLIA 4A6VA 3PKAA
chains in the Genus database with same CATH topology
4IKSA 1N51A 2EVMA 2BB7A 4B28A 3CB6A 4IECA 3CTZA 2GG2A 1WBQA 3BITA 2DFIA 2V6CA 4FUKA 1XGOA 4FO8A 1B59A 2BWTA 1QXYA 2V3YA 2GGCA 2BH3A 1YW7A 5FCHA 2BWVA 4MATA 2Q94A 4KM3A 3Q6DA 4EGEA 5CNXA 4IKUA 3PKEA 4ZWOA 1C24A 1W7VA 3IU7A 4S00A 2BHBA 4A6WA 2EVOA 1B6AA 4U6JA 4HXXA 5CE6A 2GU4A 3TAVA 1C22A 4FO7A 5CIKA 2BWSA 1KQ0A 3L24A 1XGMA 1KQ9A 1MATA 1WKMA 1JAWA 5CDEA 2G6PA 1R5GA 4RZZA 3CB5A 4IPAA 4FLKA 4QR8A 3PKCA 1C21A 2NQ7A 2Q96A 1YW9A 2GG3A 1QXZA 2OAZA 2BHDA 2BN7A 3PKBA 4ZWUA 4RGZ1 1KP0A 4PNCA 5D6EA 2Q92A 4IKRA 4U70A 2Q93A 2BWXA 1W2MA 2Q95A 5FCFA 1R58A 4U6CA 1BN5A 3D27A 2V3ZA 4S2TP 2ADUA 2BHAA 2HOWA 3FMQA 3BIPA 2GG0A 1Y1NA 3BIQA 2BHCA 4U6WA 1WL9A 4U73A 2Q8KA 4Z7MA 3TB5A 4U6ZA 4FKCA 2P99A 5D6FA 5JHUA 3MATA 2P9AA 4U71A 3S6BA 1O0XA 1QXWA 4U76A 1WN1A 2GU6A 1WY2A 5CLSA 3L7GA 4R60A 4ZWPA 4PV4A 4IU6A 2B3LA 2V3XA 2BWYA 4ZNGA 2GG8A 1BOAA 1YVMA 3FMRA 1PV9A 3MR1A 2B3HA 4S01A 5CDVA 2GG7A 3MX6A 4FLLA 3RVAA 3PKDA 3IU9A 4U75A 2GA2A 2GTXA 2EA2A 5E5BA 1XGSA 1A16A 4JUQA 4FLJA 2GU7A 2EA4A 2NQ6A 4U69A 1QZYA 2B3KA 2GGBA 5CDLA 4U6EA 4IF7A 2BWWA 2OKNA 2P98A 4RZYA 1XNZA 3IU8A 4U1BA 1CHMA 2EVCA 5JFRA 2IW2A 1WLRA 3RORA 1M35A 4S2RP 2GG5A 3FM3A 5JI6A 1C23A 2ZSGA 2MATA 1R5HA 1XGNA 2GU5A 4OOKA 2GG9A 4IKTA 1YJ3A 1YW8A 1WL6A 3IG4A 1C27A 2GZ5A 2BWUA 4IDYA 4FLIA 4A6VA 3PKAA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 4IKS A;  1N51 A;  2EVM A;  2BB7 A;  4B28 A;  3CB6 A;  4IEC A;  3CTZ A;  2GG2 A;  1WBQ A;  3BIT A;  2DFI A;  2V6C A;  4FUK A;  1XGO A;  4FO8 A;  1B59 A;  2BWT A;  1QXY A;  2V3Y A;  2GGC A;  2BH3 A;  1YW7 A;  5FCH A;  2BWV A;  4MAT A;  2Q94 A;  4KM3 A;  3Q6D A;  4EGE A;  5CNX A;  4IKU A;  3PKE A;  4ZWO A;  1C24 A;  1W7V A;  3IU7 A;  4S00 A;  2BHB A;  4A6W A;  2EVO A;  1B6A A;  4U6J A;  4HXX A;  5CE6 A;  2GU4 A;  3TAV A;  1C22 A;  4FO7 A;  5CIK A;  2BWS A;  1KQ0 A;  3L24 A;  1XGM A;  1KQ9 A;  1MAT A;  1WKM A;  1JAW A;  5CDE A;  2G6P A;  1R5G A;  4RZZ A;  3CB5 A;  4IPA A;  4FLK A;  4QR8 A;  3PKC A;  1C21 A;  2NQ7 A;  2Q96 A;  1YW9 A;  2GG3 A;  1QXZ A;  2OAZ A;  2BHD A;  2BN7 A;  3PKB A;  4ZWU A;  4RGZ 1;  1KP0 A;  4PNC A;  5D6E A;  2Q92 A;  4IKR A;  4U70 A;  2Q93 A;  2BWX A;  1W2M A;  2Q95 A;  5FCF A;  1R58 A;  4U6C A;  1BN5 A;  3D27 A;  2V3Z A;  4S2T P;  2ADU A;  2BHA A;  2HOW A;  3FMQ A;  3BIP A;  2GG0 A;  1Y1N A;  3BIQ A;  2BHC A;  4U6W A;  1WL9 A;  4U73 A;  2Q8K A;  4Z7M A;  3TB5 A;  4U6Z A;  4FKC A;  2P99 A;  5D6F A;  5JHU A;  3MAT A;  2P9A A;  4U71 A;  3S6B A;  1O0X A;  1QXW A;  4U76 A;  1WN1 A;  2GU6 A;  1WY2 A;  5CLS A;  3L7G A;  4R60 A;  4ZWP A;  4PV4 A;  4IU6 A;  2B3L A;  2V3X A;  2BWY A;  4ZNG A;  2GG8 A;  1BOA A;  1YVM A;  3FMR A;  1PV9 A;  3MR1 A;  2B3H A;  4S01 A;  5CDV A;  2GG7 A;  3MX6 A;  4FLL A;  3RVA A;  3PKD A;  3IU9 A;  4U75 A;  2GA2 A;  2GTX A;  2EA2 A;  5E5B A;  1XGS A;  1A16 A;  4JUQ A;  4FLJ A;  2GU7 A;  2EA4 A;  2NQ6 A;  4U69 A;  1QZY A;  2B3K A;  2GGB A;  5CDL A;  4U6E A;  4IF7 A;  2BWW A;  2OKN A;  2P98 A;  4RZY A;  1XNZ A;  3IU8 A;  4U1B A;  1CHM A;  2EVC A;  5JFR A;  2IW2 A;  1WLR A;  3ROR A;  1M35 A;  4S2R P;  2GG5 A;  3FM3 A;  5JI6 A;  1C23 A;  2ZSG A;  2MAT A;  1R5H A;  1XGN A;  2GU5 A;  4OOK A;  2GG9 A;  4IKT A;  1YJ3 A;  1YW8 A;  1WL6 A;  3IG4 A;  1C27 A;  2GZ5 A;  2BWU A;  4IDY A;  4FLI A;  4A6V A;  3PKA A; 
#chains in the Genus database with same CATH topology
 4IKS A;  1N51 A;  2EVM A;  2BB7 A;  4B28 A;  3CB6 A;  4IEC A;  3CTZ A;  2GG2 A;  1WBQ A;  3BIT A;  2DFI A;  2V6C A;  4FUK A;  1XGO A;  4FO8 A;  1B59 A;  2BWT A;  1QXY A;  2V3Y A;  2GGC A;  2BH3 A;  1YW7 A;  5FCH A;  2BWV A;  4MAT A;  2Q94 A;  4KM3 A;  3Q6D A;  4EGE A;  5CNX A;  4IKU A;  3PKE A;  4ZWO A;  1C24 A;  1W7V A;  3IU7 A;  4S00 A;  2BHB A;  4A6W A;  2EVO A;  1B6A A;  4U6J A;  4HXX A;  5CE6 A;  2GU4 A;  3TAV A;  1C22 A;  4FO7 A;  5CIK A;  2BWS A;  1KQ0 A;  3L24 A;  1XGM A;  1KQ9 A;  1MAT A;  1WKM A;  1JAW A;  5CDE A;  2G6P A;  1R5G A;  4RZZ A;  3CB5 A;  4IPA A;  4FLK A;  4QR8 A;  3PKC A;  1C21 A;  2NQ7 A;  2Q96 A;  1YW9 A;  2GG3 A;  1QXZ A;  2OAZ A;  2BHD A;  2BN7 A;  3PKB A;  4ZWU A;  4RGZ 1;  1KP0 A;  4PNC A;  5D6E A;  2Q92 A;  4IKR A;  4U70 A;  2Q93 A;  2BWX A;  1W2M A;  2Q95 A;  5FCF A;  1R58 A;  4U6C A;  1BN5 A;  3D27 A;  2V3Z A;  4S2T P;  2ADU A;  2BHA A;  2HOW A;  3FMQ A;  3BIP A;  2GG0 A;  1Y1N A;  3BIQ A;  2BHC A;  4U6W A;  1WL9 A;  4U73 A;  2Q8K A;  4Z7M A;  3TB5 A;  4U6Z A;  4FKC A;  2P99 A;  5D6F A;  5JHU A;  3MAT A;  2P9A A;  4U71 A;  3S6B A;  1O0X A;  1QXW A;  4U76 A;  1WN1 A;  2GU6 A;  1WY2 A;  5CLS A;  3L7G A;  4R60 A;  4ZWP A;  4PV4 A;  4IU6 A;  2B3L A;  2V3X A;  2BWY A;  4ZNG A;  2GG8 A;  1BOA A;  1YVM A;  3FMR A;  1PV9 A;  3MR1 A;  2B3H A;  4S01 A;  5CDV A;  2GG7 A;  3MX6 A;  4FLL A;  3RVA A;  3PKD A;  3IU9 A;  4U75 A;  2GA2 A;  2GTX A;  2EA2 A;  5E5B A;  1XGS A;  1A16 A;  4JUQ A;  4FLJ A;  2GU7 A;  2EA4 A;  2NQ6 A;  4U69 A;  1QZY A;  2B3K A;  2GGB A;  5CDL A;  4U6E A;  4IF7 A;  2BWW A;  2OKN A;  2P98 A;  4RZY A;  1XNZ A;  3IU8 A;  4U1B A;  1CHM A;  2EVC A;  5JFR A;  2IW2 A;  1WLR A;  3ROR A;  1M35 A;  4S2R P;  2GG5 A;  3FM3 A;  5JI6 A;  1C23 A;  2ZSG A;  2MAT A;  1R5H A;  1XGN A;  2GU5 A;  4OOK A;  2GG9 A;  4IKT A;  1YJ3 A;  1YW8 A;  1WL6 A;  3IG4 A;  1C27 A;  2GZ5 A;  2BWU A;  4IDY A;  4FLI A;  4A6V A;  3PKA A; 
#chains in the Genus database with same CATH homology
 4IKS A;  1N51 A;  2EVM A;  2BB7 A;  4B28 A;  3CB6 A;  4IEC A;  3CTZ A;  2GG2 A;  1WBQ A;  3BIT A;  2DFI A;  2V6C A;  4FUK A;  1XGO A;  4FO8 A;  1B59 A;  2BWT A;  1QXY A;  2V3Y A;  2GGC A;  2BH3 A;  1YW7 A;  5FCH A;  2BWV A;  4MAT A;  2Q94 A;  4KM3 A;  3Q6D A;  4EGE A;  5CNX A;  4IKU A;  3PKE A;  4ZWO A;  1C24 A;  1W7V A;  3IU7 A;  4S00 A;  2BHB A;  4A6W A;  2EVO A;  1B6A A;  4U6J A;  4HXX A;  5CE6 A;  2GU4 A;  3TAV A;  1C22 A;  4FO7 A;  5CIK A;  2BWS A;  1KQ0 A;  3L24 A;  1XGM A;  1KQ9 A;  1MAT A;  1WKM A;  1JAW A;  5CDE A;  2G6P A;  1R5G A;  4RZZ A;  3CB5 A;  4IPA A;  4FLK A;  4QR8 A;  3PKC A;  1C21 A;  2NQ7 A;  2Q96 A;  1YW9 A;  2GG3 A;  1QXZ A;  2OAZ A;  2BHD A;  2BN7 A;  3PKB A;  4ZWU A;  4RGZ 1;  1KP0 A;  4PNC A;  5D6E A;  2Q92 A;  4IKR A;  4U70 A;  2Q93 A;  2BWX A;  1W2M A;  2Q95 A;  5FCF A;  1R58 A;  4U6C A;  1BN5 A;  3D27 A;  2V3Z A;  4S2T P;  2ADU A;  2BHA A;  2HOW A;  3FMQ A;  3BIP A;  2GG0 A;  1Y1N A;  3BIQ A;  2BHC A;  4U6W A;  1WL9 A;  4U73 A;  2Q8K A;  4Z7M A;  3TB5 A;  4U6Z A;  4FKC A;  2P99 A;  5D6F A;  5JHU A;  3MAT A;  2P9A A;  4U71 A;  3S6B A;  1O0X A;  1QXW A;  4U76 A;  1WN1 A;  2GU6 A;  1WY2 A;  5CLS A;  3L7G A;  4R60 A;  4ZWP A;  4PV4 A;  4IU6 A;  2B3L A;  2V3X A;  2BWY A;  4ZNG A;  2GG8 A;  1BOA A;  1YVM A;  3FMR A;  1PV9 A;  3MR1 A;  2B3H A;  4S01 A;  5CDV A;  2GG7 A;  3MX6 A;  4FLL A;  3RVA A;  3PKD A;  3IU9 A;  4U75 A;  2GA2 A;  2GTX A;  2EA2 A;  5E5B A;  1XGS A;  1A16 A;  4JUQ A;  4FLJ A;  2GU7 A;  2EA4 A;  2NQ6 A;  4U69 A;  1QZY A;  2B3K A;  2GGB A;  5CDL A;  4U6E A;  4IF7 A;  2BWW A;  2OKN A;  2P98 A;  4RZY A;  1XNZ A;  3IU8 A;  4U1B A;  1CHM A;  2EVC A;  5JFR A;  2IW2 A;  1WLR A;  3ROR A;  1M35 A;  4S2R P;  2GG5 A;  3FM3 A;  5JI6 A;  1C23 A;  2ZSG A;  2MAT A;  1R5H A;  1XGN A;  2GU5 A;  4OOK A;  2GG9 A;  4IKT A;  1YJ3 A;  1YW8 A;  1WL6 A;  3IG4 A;  1C27 A;  2GZ5 A;  2BWU A;  4IDY A;  4FLI A;  4A6V A;  3PKA A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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