4OOKA

Third metal bound m.tuberculosis methionine aminopeptidase
Total Genus 88
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTAL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase 2
publication title Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 88
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2014-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4ookA01
1WN1A 4IU6A 4S2TP 4PNCA 2Q93A 4U1BA 1QXZA 2GA2A 5CE6A 2GU6A 5CDEA 4B28A 4RGZ1 1WL9A 2B3KA 4U69A 2EVOA 4S01A 1WY2A 2BWVA 2BWYA 3MX6A 3PKDA 3PKBA 2BWUA 2NQ6A 1JAWA 2V3YA 3D27A 3TB5A 2BH3A 2BHCA 5D6FA 2GG5A 2GG3A 4FLKA 3PKCA 2NQ7A 1QXWA 4U6WA 4S2RP 3IG4A 1PV9A 1XGNA 2P9AA 1Y1NA 4MATA 5CLSA 4FO8A 2EA4A 4IKRA 1YW7A 1YW8A 3CTZA 2GZ5A 1W2MA 2P99A 2BWTA 2GG9A 2Q95A 1KP0A 3FMQA 5CDVA 1QXYA 3IU8A 4FUKA 2V3XA 4IPAA 2BHAA 2GGBA 3L7GA 1R58A 4HXXA 3RORA 2Q8KA 3IU9A 3MATA 2MATA 2V3ZA 3CB6A 4QR8A 1BN5A 2GU4A 4U71A 5CIKA 2BN7A 3L24A 1W7VA 1XGSA 1QZYA 2G6PA 5JFRA 3BITA 1WKMA 1C22A 2EVMA 3MR1A 2GU5A 5CNXA 5FCHA 2GG7A 4IKUA 4U6JA 4FLLA 4PV4A 5CDLA 2BWSA 4FLJA 4FO7A 2BWWA 2EA2A 5E5BA 1B59A 2B3HA 2BHBA 4U6ZA 4U70A 2Q94A 3CB5A 4EGEA 1WLRA 1XGOA 1R5HA 4IKTA 4S00A 4ZWOA 2IW2A 2GTXA 1KQ9A 1YJ3A 1N51A 2HOWA 1R5GA 1CHMA 1O0XA 4IECA 1XNZA 1WBQA 1KQ0A 1C21A 1C23A 2ZSGA 2GG0A 4U76A 1YVMA 2P98A 3BIPA 3BIQA 4U6EA 3FM3A 2GGCA 2OAZA 1A16A 1M35A 4ZWPA 2EVCA 5D6EA 2ADUA 2GG8A 4R60A 4RZZA 4ZWUA 4A6VA 2Q92A 2V6CA 4RZYA 5JI6A 1C24A 3FMRA 4KM3A 4Z7MA 1XGMA 1YW9A 4FKCA 2BHDA 1B6AA 4IDYA 2OKNA 4IKSA 4OOKA 3TAVA 4FLIA 3S6BA 3Q6DA 3PKEA 2Q96A 3RVAA 2GU7A 4A6WA 3IU7A 4IF7A 1C27A 3PKAA 1MATA 4U73A 4U6CA 2B3LA 5JHUA 1BOAA 4U75A 5FCFA 2BB7A 4ZNGA 2GG2A 2BWXA 1WL6A 4JUQA 2DFIA
chains in the Genus database with same CATH superfamily
1WN1A 4IU6A 4S2TP 4PNCA 2Q93A 4U1BA 1QXZA 2GA2A 5CE6A 2GU6A 5CDEA 4B28A 4RGZ1 1WL9A 2B3KA 4U69A 2EVOA 4S01A 1WY2A 2BWVA 2BWYA 3MX6A 3PKDA 3PKBA 2BWUA 2NQ6A 1JAWA 2V3YA 3D27A 3TB5A 2BH3A 2BHCA 5D6FA 2GG5A 2GG3A 4FLKA 3PKCA 2NQ7A 1QXWA 4U6WA 4S2RP 3IG4A 1PV9A 1XGNA 2P9AA 1Y1NA 4MATA 5CLSA 4FO8A 2EA4A 4IKRA 1YW7A 1YW8A 3CTZA 2GZ5A 1W2MA 2P99A 2BWTA 2GG9A 2Q95A 1KP0A 3FMQA 5CDVA 1QXYA 3IU8A 4FUKA 2V3XA 4IPAA 2BHAA 2GGBA 3L7GA 1R58A 4HXXA 3RORA 2Q8KA 3IU9A 3MATA 2MATA 2V3ZA 3CB6A 4QR8A 1BN5A 2GU4A 4U71A 5CIKA 2BN7A 3L24A 1W7VA 1XGSA 1QZYA 2G6PA 5JFRA 3BITA 1WKMA 1C22A 2EVMA 3MR1A 2GU5A 5CNXA 5FCHA 2GG7A 4IKUA 4U6JA 4FLLA 4PV4A 5CDLA 2BWSA 4FLJA 4FO7A 2BWWA 2EA2A 5E5BA 1B59A 2B3HA 2BHBA 4U6ZA 4U70A 2Q94A 3CB5A 4EGEA 1WLRA 1XGOA 1R5HA 4IKTA 4S00A 4ZWOA 2IW2A 2GTXA 1KQ9A 1YJ3A 1N51A 2HOWA 1R5GA 1CHMA 1O0XA 4IECA 1XNZA 1WBQA 1KQ0A 1C21A 1C23A 2ZSGA 2GG0A 4U76A 1YVMA 2P98A 3BIPA 3BIQA 4U6EA 3FM3A 2GGCA 2OAZA 1A16A 1M35A 4ZWPA 2EVCA 5D6EA 2ADUA 2GG8A 4R60A 4RZZA 4ZWUA 4A6VA 2Q92A 2V6CA 4RZYA 5JI6A 1C24A 3FMRA 4KM3A 4Z7MA 1XGMA 1YW9A 4FKCA 2BHDA 1B6AA 4IDYA 2OKNA 4IKSA 4OOKA 3TAVA 4FLIA 3S6BA 3Q6DA 3PKEA 2Q96A 3RVAA 2GU7A 4A6WA 3IU7A 4IF7A 1C27A 3PKAA 1MATA 4U73A 4U6CA 2B3LA 5JHUA 1BOAA 4U75A 5FCFA 2BB7A 4ZNGA 2GG2A 2BWXA 1WL6A 4JUQA 2DFIA
chains in the Genus database with same CATH topology
1WN1A 4IU6A 4S2TP 4PNCA 2Q93A 4U1BA 1QXZA 2GA2A 5CE6A 2GU6A 5CDEA 4B28A 4RGZ1 1WL9A 2B3KA 4U69A 2EVOA 4S01A 1WY2A 2BWVA 2BWYA 3MX6A 3PKDA 3PKBA 2BWUA 2NQ6A 1JAWA 2V3YA 3D27A 3TB5A 2BH3A 2BHCA 5D6FA 2GG5A 2GG3A 4FLKA 3PKCA 2NQ7A 1QXWA 4U6WA 4S2RP 3IG4A 1PV9A 1XGNA 2P9AA 1Y1NA 4MATA 5CLSA 4FO8A 2EA4A 4IKRA 1YW7A 1YW8A 3CTZA 2GZ5A 1W2MA 2P99A 2BWTA 2GG9A 2Q95A 1KP0A 3FMQA 5CDVA 1QXYA 3IU8A 4FUKA 2V3XA 4IPAA 2BHAA 2GGBA 3L7GA 1R58A 4HXXA 3RORA 2Q8KA 3IU9A 3MATA 2MATA 2V3ZA 3CB6A 4QR8A 1BN5A 2GU4A 4U71A 5CIKA 2BN7A 3L24A 1W7VA 1XGSA 1QZYA 2G6PA 5JFRA 3BITA 1WKMA 1C22A 2EVMA 3MR1A 2GU5A 5CNXA 5FCHA 2GG7A 4IKUA 4U6JA 4FLLA 4PV4A 5CDLA 2BWSA 4FLJA 4FO7A 2BWWA 2EA2A 5E5BA 1B59A 2B3HA 2BHBA 4U6ZA 4U70A 2Q94A 3CB5A 4EGEA 1WLRA 1XGOA 1R5HA 4IKTA 4S00A 4ZWOA 2IW2A 2GTXA 1KQ9A 1YJ3A 1N51A 2HOWA 1R5GA 1CHMA 1O0XA 4IECA 1XNZA 1WBQA 1KQ0A 1C21A 1C23A 2ZSGA 2GG0A 4U76A 1YVMA 2P98A 3BIPA 3BIQA 4U6EA 3FM3A 2GGCA 2OAZA 1A16A 1M35A 4ZWPA 2EVCA 5D6EA 2ADUA 2GG8A 4R60A 4RZZA 4ZWUA 4A6VA 2Q92A 2V6CA 4RZYA 5JI6A 1C24A 3FMRA 4KM3A 4Z7MA 1XGMA 1YW9A 4FKCA 2BHDA 1B6AA 4IDYA 2OKNA 4IKSA 4OOKA 3TAVA 4FLIA 3S6BA 3Q6DA 3PKEA 2Q96A 3RVAA 2GU7A 4A6WA 3IU7A 4IF7A 1C27A 3PKAA 1MATA 4U73A 4U6CA 2B3LA 5JHUA 1BOAA 4U75A 5FCFA 2BB7A 4ZNGA 2GG2A 2BWXA 1WL6A 4JUQA 2DFIA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1WN1 A;  4IU6 A;  4S2T P;  4PNC A;  2Q93 A;  4U1B A;  1QXZ A;  2GA2 A;  5CE6 A;  2GU6 A;  5CDE A;  4B28 A;  4RGZ 1;  1WL9 A;  2B3K A;  4U69 A;  2EVO A;  4S01 A;  1WY2 A;  2BWV A;  2BWY A;  3MX6 A;  3PKD A;  3PKB A;  2BWU A;  2NQ6 A;  1JAW A;  2V3Y A;  3D27 A;  3TB5 A;  2BH3 A;  2BHC A;  5D6F A;  2GG5 A;  2GG3 A;  4FLK A;  3PKC A;  2NQ7 A;  1QXW A;  4U6W A;  4S2R P;  3IG4 A;  1PV9 A;  1XGN A;  2P9A A;  1Y1N A;  4MAT A;  5CLS A;  4FO8 A;  2EA4 A;  4IKR A;  1YW7 A;  1YW8 A;  3CTZ A;  2GZ5 A;  1W2M A;  2P99 A;  2BWT A;  2GG9 A;  2Q95 A;  1KP0 A;  3FMQ A;  5CDV A;  1QXY A;  3IU8 A;  4FUK A;  2V3X A;  4IPA A;  2BHA A;  2GGB A;  3L7G A;  1R58 A;  4HXX A;  3ROR A;  2Q8K A;  3IU9 A;  3MAT A;  2MAT A;  2V3Z A;  3CB6 A;  4QR8 A;  1BN5 A;  2GU4 A;  4U71 A;  5CIK A;  2BN7 A;  3L24 A;  1W7V A;  1XGS A;  1QZY A;  2G6P A;  5JFR A;  3BIT A;  1WKM A;  1C22 A;  2EVM A;  3MR1 A;  2GU5 A;  5CNX A;  5FCH A;  2GG7 A;  4IKU A;  4U6J A;  4FLL A;  4PV4 A;  5CDL A;  2BWS A;  4FLJ A;  4FO7 A;  2BWW A;  2EA2 A;  5E5B A;  1B59 A;  2B3H A;  2BHB A;  4U6Z A;  4U70 A;  2Q94 A;  3CB5 A;  4EGE A;  1WLR A;  1XGO A;  1R5H A;  4IKT A;  4S00 A;  4ZWO A;  2IW2 A;  2GTX A;  1KQ9 A;  1YJ3 A;  1N51 A;  2HOW A;  1R5G A;  1CHM A;  1O0X A;  4IEC A;  1XNZ A;  1WBQ A;  1KQ0 A;  1C21 A;  1C23 A;  2ZSG A;  2GG0 A;  4U76 A;  1YVM A;  2P98 A;  3BIP A;  3BIQ A;  4U6E A;  3FM3 A;  2GGC A;  2OAZ A;  1A16 A;  1M35 A;  4ZWP A;  2EVC A;  5D6E A;  2ADU A;  2GG8 A;  4R60 A;  4RZZ A;  4ZWU A;  4A6V A;  2Q92 A;  2V6C A;  4RZY A;  5JI6 A;  1C24 A;  3FMR A;  4KM3 A;  4Z7M A;  1XGM A;  1YW9 A;  4FKC A;  2BHD A;  1B6A A;  4IDY A;  2OKN A;  4IKS A;  4OOK A;  3TAV A;  4FLI A;  3S6B A;  3Q6D A;  3PKE A;  2Q96 A;  3RVA A;  2GU7 A;  4A6W A;  3IU7 A;  4IF7 A;  1C27 A;  3PKA A;  1MAT A;  4U73 A;  4U6C A;  2B3L A;  5JHU A;  1BOA A;  4U75 A;  5FCF A;  2BB7 A;  4ZNG A;  2GG2 A;  2BWX A;  1WL6 A;  4JUQ A;  2DFI A; 
#chains in the Genus database with same CATH topology
 1WN1 A;  4IU6 A;  4S2T P;  4PNC A;  2Q93 A;  4U1B A;  1QXZ A;  2GA2 A;  5CE6 A;  2GU6 A;  5CDE A;  4B28 A;  4RGZ 1;  1WL9 A;  2B3K A;  4U69 A;  2EVO A;  4S01 A;  1WY2 A;  2BWV A;  2BWY A;  3MX6 A;  3PKD A;  3PKB A;  2BWU A;  2NQ6 A;  1JAW A;  2V3Y A;  3D27 A;  3TB5 A;  2BH3 A;  2BHC A;  5D6F A;  2GG5 A;  2GG3 A;  4FLK A;  3PKC A;  2NQ7 A;  1QXW A;  4U6W A;  4S2R P;  3IG4 A;  1PV9 A;  1XGN A;  2P9A A;  1Y1N A;  4MAT A;  5CLS A;  4FO8 A;  2EA4 A;  4IKR A;  1YW7 A;  1YW8 A;  3CTZ A;  2GZ5 A;  1W2M A;  2P99 A;  2BWT A;  2GG9 A;  2Q95 A;  1KP0 A;  3FMQ A;  5CDV A;  1QXY A;  3IU8 A;  4FUK A;  2V3X A;  4IPA A;  2BHA A;  2GGB A;  3L7G A;  1R58 A;  4HXX A;  3ROR A;  2Q8K A;  3IU9 A;  3MAT A;  2MAT A;  2V3Z A;  3CB6 A;  4QR8 A;  1BN5 A;  2GU4 A;  4U71 A;  5CIK A;  2BN7 A;  3L24 A;  1W7V A;  1XGS A;  1QZY A;  2G6P A;  5JFR A;  3BIT A;  1WKM A;  1C22 A;  2EVM A;  3MR1 A;  2GU5 A;  5CNX A;  5FCH A;  2GG7 A;  4IKU A;  4U6J A;  4FLL A;  4PV4 A;  5CDL A;  2BWS A;  4FLJ A;  4FO7 A;  2BWW A;  2EA2 A;  5E5B A;  1B59 A;  2B3H A;  2BHB A;  4U6Z A;  4U70 A;  2Q94 A;  3CB5 A;  4EGE A;  1WLR A;  1XGO A;  1R5H A;  4IKT A;  4S00 A;  4ZWO A;  2IW2 A;  2GTX A;  1KQ9 A;  1YJ3 A;  1N51 A;  2HOW A;  1R5G A;  1CHM A;  1O0X A;  4IEC A;  1XNZ A;  1WBQ A;  1KQ0 A;  1C21 A;  1C23 A;  2ZSG A;  2GG0 A;  4U76 A;  1YVM A;  2P98 A;  3BIP A;  3BIQ A;  4U6E A;  3FM3 A;  2GGC A;  2OAZ A;  1A16 A;  1M35 A;  4ZWP A;  2EVC A;  5D6E A;  2ADU A;  2GG8 A;  4R60 A;  4RZZ A;  4ZWU A;  4A6V A;  2Q92 A;  2V6C A;  4RZY A;  5JI6 A;  1C24 A;  3FMR A;  4KM3 A;  4Z7M A;  1XGM A;  1YW9 A;  4FKC A;  2BHD A;  1B6A A;  4IDY A;  2OKN A;  4IKS A;  4OOK A;  3TAV A;  4FLI A;  3S6B A;  3Q6D A;  3PKE A;  2Q96 A;  3RVA A;  2GU7 A;  4A6W A;  3IU7 A;  4IF7 A;  1C27 A;  3PKA A;  1MAT A;  4U73 A;  4U6C A;  2B3L A;  5JHU A;  1BOA A;  4U75 A;  5FCF A;  2BB7 A;  4ZNG A;  2GG2 A;  2BWX A;  1WL6 A;  4JUQ A;  2DFI A; 
#chains in the Genus database with same CATH homology
 1WN1 A;  4IU6 A;  4S2T P;  4PNC A;  2Q93 A;  4U1B A;  1QXZ A;  2GA2 A;  5CE6 A;  2GU6 A;  5CDE A;  4B28 A;  4RGZ 1;  1WL9 A;  2B3K A;  4U69 A;  2EVO A;  4S01 A;  1WY2 A;  2BWV A;  2BWY A;  3MX6 A;  3PKD A;  3PKB A;  2BWU A;  2NQ6 A;  1JAW A;  2V3Y A;  3D27 A;  3TB5 A;  2BH3 A;  2BHC A;  5D6F A;  2GG5 A;  2GG3 A;  4FLK A;  3PKC A;  2NQ7 A;  1QXW A;  4U6W A;  4S2R P;  3IG4 A;  1PV9 A;  1XGN A;  2P9A A;  1Y1N A;  4MAT A;  5CLS A;  4FO8 A;  2EA4 A;  4IKR A;  1YW7 A;  1YW8 A;  3CTZ A;  2GZ5 A;  1W2M A;  2P99 A;  2BWT A;  2GG9 A;  2Q95 A;  1KP0 A;  3FMQ A;  5CDV A;  1QXY A;  3IU8 A;  4FUK A;  2V3X A;  4IPA A;  2BHA A;  2GGB A;  3L7G A;  1R58 A;  4HXX A;  3ROR A;  2Q8K A;  3IU9 A;  3MAT A;  2MAT A;  2V3Z A;  3CB6 A;  4QR8 A;  1BN5 A;  2GU4 A;  4U71 A;  5CIK A;  2BN7 A;  3L24 A;  1W7V A;  1XGS A;  1QZY A;  2G6P A;  5JFR A;  3BIT A;  1WKM A;  1C22 A;  2EVM A;  3MR1 A;  2GU5 A;  5CNX A;  5FCH A;  2GG7 A;  4IKU A;  4U6J A;  4FLL A;  4PV4 A;  5CDL A;  2BWS A;  4FLJ A;  4FO7 A;  2BWW A;  2EA2 A;  5E5B A;  1B59 A;  2B3H A;  2BHB A;  4U6Z A;  4U70 A;  2Q94 A;  3CB5 A;  4EGE A;  1WLR A;  1XGO A;  1R5H A;  4IKT A;  4S00 A;  4ZWO A;  2IW2 A;  2GTX A;  1KQ9 A;  1YJ3 A;  1N51 A;  2HOW A;  1R5G A;  1CHM A;  1O0X A;  4IEC A;  1XNZ A;  1WBQ A;  1KQ0 A;  1C21 A;  1C23 A;  2ZSG A;  2GG0 A;  4U76 A;  1YVM A;  2P98 A;  3BIP A;  3BIQ A;  4U6E A;  3FM3 A;  2GGC A;  2OAZ A;  1A16 A;  1M35 A;  4ZWP A;  2EVC A;  5D6E A;  2ADU A;  2GG8 A;  4R60 A;  4RZZ A;  4ZWU A;  4A6V A;  2Q92 A;  2V6C A;  4RZY A;  5JI6 A;  1C24 A;  3FMR A;  4KM3 A;  4Z7M A;  1XGM A;  1YW9 A;  4FKC A;  2BHD A;  1B6A A;  4IDY A;  2OKN A;  4IKS A;  4OOK A;  3TAV A;  4FLI A;  3S6B A;  3Q6D A;  3PKE A;  2Q96 A;  3RVA A;  2GU7 A;  4A6W A;  3IU7 A;  4IF7 A;  1C27 A;  3PKA A;  1MAT A;  4U73 A;  4U6C A;  2B3L A;  5JHU A;  1BOA A;  4U75 A;  5FCF A;  2BB7 A;  4ZNG A;  2GG2 A;  2BWX A;  1WL6 A;  4JUQ A;  2DFI A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...