4OOKA

Third metal bound m.tuberculosis methionine aminopeptidase
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTAL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase 2
publication title Selective targeting of the conserved active site cysteine of Mycobacterium tuberculosis methionine aminopeptidase with electrophilic reagents
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 88
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2014-02-03

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 4ookA01
2GG0A 1R5GA 2NQ7A 3PKBA 2BWUA 1A16A 5D6FA 5CDVA 1QXZA 1YVMA 2P98A 3S6BA 2OAZA 4PNCA 4U69A 2BWVA 4FO7A 4B28A 2BWTA 4U6CA 1WL9A 4MATA 2OKNA 5CIKA 1C24A 1YW7A 5CNXA 1WL6A 2V3XA 1B6AA 4JUQA 1QXWA 2BHBA 2V3ZA 3IU7A 3MX6A 1CHMA 2BHDA 2ZSGA 1KP0A 2B3HA 2GU6A 3PKAA 4RZZA 4S2TP 1WKMA 4IKTA 4A6WA 2V6CA 2Q93A 3FMRA 3TB5A 4IDYA 1WBQA 2EVMA 2GG9A 2GGBA 3PKDA 5D6EA 3PKEA 2V3YA 4EGEA 1XGMA 4U73A 2NQ6A 4FLJA 4FUKA 1XNZA 2BWWA 4PV4A 5JFRA 1WY2A 2ADUA 2GA2A 2Q94A 2GZ5A 1WLRA 4U6JA 3MR1A 3L24A 2GG7A 3IG4A 2Q95A 4KM3A 2Q96A 4IECA 1Y1NA 4S01A 4U6EA 1PV9A 4U6WA 4U75A 2BWXA 5CDEA 1YW8A 3PKCA 4U76A 1MATA 4FO8A 1R5HA 3IU9A 4ZWOA 1C22A 4S2RP 5CLSA 4A6VA 4IKRA 1WN1A 2P9AA 2Q8KA 3RVAA 2EVOA 1XGNA 4ZWUA 4U71A 4U6ZA 2BN7A 3FM3A 1XGSA 2B3LA 4ZWPA 4R60A 4U70A 3CB5A 2GG3A 1KQ9A 3BIQA 1KQ0A 4U1BA 4FLIA 3BITA 2EVCA 4IKUA 1C23A 2GTXA 5FCFA 5E5BA 2B3KA 2GG2A 4RGZ1 4ZNGA 3FMQA 1QXYA 2DFIA 4Z7MA 4HXXA 2EA4A 4FLLA 1C21A 2IW2A 4IKSA 4IPAA 1BN5A 1C27A 1YJ3A 2GU7A 2GU5A 1YW9A 3CTZA 3TAVA 3D27A 4FLKA 1BOAA 2BH3A 4FKCA 4IF7A 1B59A 2GGCA 1JAWA 1XGOA 2GG8A 1O0XA 3L7GA 4S00A 4RZYA 2EA2A 4IU6A 2G6PA 5CE6A 2GG5A 5FCHA 2HOWA 1N51A 5JI6A 1QZYA 2Q92A 2BHCA 2BB7A 3Q6DA 1W2MA 2GU4A 4OOKA 2BWYA 3MATA 5JHUA 3IU8A 3RORA 2P99A 3CB6A 2MATA 3BIPA 4QR8A 2BHAA 2BWSA 1M35A 5CDLA 1W7VA 1R58A
chains in the Genus database with same CATH superfamily
2GG0A 1R5GA 2NQ7A 3PKBA 2BWUA 1A16A 5D6FA 5CDVA 1QXZA 1YVMA 2P98A 3S6BA 2OAZA 4PNCA 4U69A 2BWVA 4FO7A 4B28A 2BWTA 4U6CA 1WL9A 4MATA 2OKNA 5CIKA 1C24A 1YW7A 5CNXA 1WL6A 2V3XA 1B6AA 4JUQA 1QXWA 2BHBA 2V3ZA 3IU7A 3MX6A 1CHMA 2BHDA 2ZSGA 1KP0A 2B3HA 2GU6A 3PKAA 4RZZA 4S2TP 1WKMA 4IKTA 4A6WA 2V6CA 2Q93A 3FMRA 3TB5A 4IDYA 1WBQA 2EVMA 2GG9A 2GGBA 3PKDA 5D6EA 3PKEA 2V3YA 4EGEA 1XGMA 4U73A 2NQ6A 4FLJA 4FUKA 1XNZA 2BWWA 4PV4A 5JFRA 1WY2A 2ADUA 2GA2A 2Q94A 2GZ5A 1WLRA 4U6JA 3MR1A 3L24A 2GG7A 3IG4A 2Q95A 4KM3A 2Q96A 4IECA 1Y1NA 4S01A 4U6EA 1PV9A 4U6WA 4U75A 2BWXA 5CDEA 1YW8A 3PKCA 4U76A 1MATA 4FO8A 1R5HA 3IU9A 4ZWOA 1C22A 4S2RP 5CLSA 4A6VA 4IKRA 1WN1A 2P9AA 2Q8KA 3RVAA 2EVOA 1XGNA 4ZWUA 4U71A 4U6ZA 2BN7A 3FM3A 1XGSA 2B3LA 4ZWPA 4R60A 4U70A 3CB5A 2GG3A 1KQ9A 3BIQA 1KQ0A 4U1BA 4FLIA 3BITA 2EVCA 4IKUA 1C23A 2GTXA 5FCFA 5E5BA 2B3KA 2GG2A 4RGZ1 4ZNGA 3FMQA 1QXYA 2DFIA 4Z7MA 4HXXA 2EA4A 4FLLA 1C21A 2IW2A 4IKSA 4IPAA 1BN5A 1C27A 1YJ3A 2GU7A 2GU5A 1YW9A 3CTZA 3TAVA 3D27A 4FLKA 1BOAA 2BH3A 4FKCA 4IF7A 1B59A 2GGCA 1JAWA 1XGOA 2GG8A 1O0XA 3L7GA 4S00A 4RZYA 2EA2A 4IU6A 2G6PA 5CE6A 2GG5A 5FCHA 2HOWA 1N51A 5JI6A 1QZYA 2Q92A 2BHCA 2BB7A 3Q6DA 1W2MA 2GU4A 4OOKA 2BWYA 3MATA 5JHUA 3IU8A 3RORA 2P99A 3CB6A 2MATA 3BIPA 4QR8A 2BHAA 2BWSA 1M35A 5CDLA 1W7VA 1R58A
chains in the Genus database with same CATH topology
2GG0A 1R5GA 2NQ7A 3PKBA 2BWUA 1A16A 5D6FA 5CDVA 1QXZA 1YVMA 2P98A 3S6BA 2OAZA 4PNCA 4U69A 2BWVA 4FO7A 4B28A 2BWTA 4U6CA 1WL9A 4MATA 2OKNA 5CIKA 1C24A 1YW7A 5CNXA 1WL6A 2V3XA 1B6AA 4JUQA 1QXWA 2BHBA 2V3ZA 3IU7A 3MX6A 1CHMA 2BHDA 2ZSGA 1KP0A 2B3HA 2GU6A 3PKAA 4RZZA 4S2TP 1WKMA 4IKTA 4A6WA 2V6CA 2Q93A 3FMRA 3TB5A 4IDYA 1WBQA 2EVMA 2GG9A 2GGBA 3PKDA 5D6EA 3PKEA 2V3YA 4EGEA 1XGMA 4U73A 2NQ6A 4FLJA 4FUKA 1XNZA 2BWWA 4PV4A 5JFRA 1WY2A 2ADUA 2GA2A 2Q94A 2GZ5A 1WLRA 4U6JA 3MR1A 3L24A 2GG7A 3IG4A 2Q95A 4KM3A 2Q96A 4IECA 1Y1NA 4S01A 4U6EA 1PV9A 4U6WA 4U75A 2BWXA 5CDEA 1YW8A 3PKCA 4U76A 1MATA 4FO8A 1R5HA 3IU9A 4ZWOA 1C22A 4S2RP 5CLSA 4A6VA 4IKRA 1WN1A 2P9AA 2Q8KA 3RVAA 2EVOA 1XGNA 4ZWUA 4U71A 4U6ZA 2BN7A 3FM3A 1XGSA 2B3LA 4ZWPA 4R60A 4U70A 3CB5A 2GG3A 1KQ9A 3BIQA 1KQ0A 4U1BA 4FLIA 3BITA 2EVCA 4IKUA 1C23A 2GTXA 5FCFA 5E5BA 2B3KA 2GG2A 4RGZ1 4ZNGA 3FMQA 1QXYA 2DFIA 4Z7MA 4HXXA 2EA4A 4FLLA 1C21A 2IW2A 4IKSA 4IPAA 1BN5A 1C27A 1YJ3A 2GU7A 2GU5A 1YW9A 3CTZA 3TAVA 3D27A 4FLKA 1BOAA 2BH3A 4FKCA 4IF7A 1B59A 2GGCA 1JAWA 1XGOA 2GG8A 1O0XA 3L7GA 4S00A 4RZYA 2EA2A 4IU6A 2G6PA 5CE6A 2GG5A 5FCHA 2HOWA 1N51A 5JI6A 1QZYA 2Q92A 2BHCA 2BB7A 3Q6DA 1W2MA 2GU4A 4OOKA 2BWYA 3MATA 5JHUA 3IU8A 3RORA 2P99A 3CB6A 2MATA 3BIPA 4QR8A 2BHAA 2BWSA 1M35A 5CDLA 1W7VA 1R58A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG0 A;  1R5G A;  2NQ7 A;  3PKB A;  2BWU A;  1A16 A;  5D6F A;  5CDV A;  1QXZ A;  1YVM A;  2P98 A;  3S6B A;  2OAZ A;  4PNC A;  4U69 A;  2BWV A;  4FO7 A;  4B28 A;  2BWT A;  4U6C A;  1WL9 A;  4MAT A;  2OKN A;  5CIK A;  1C24 A;  1YW7 A;  5CNX A;  1WL6 A;  2V3X A;  1B6A A;  4JUQ A;  1QXW A;  2BHB A;  2V3Z A;  3IU7 A;  3MX6 A;  1CHM A;  2BHD A;  2ZSG A;  1KP0 A;  2B3H A;  2GU6 A;  3PKA A;  4RZZ A;  4S2T P;  1WKM A;  4IKT A;  4A6W A;  2V6C A;  2Q93 A;  3FMR A;  3TB5 A;  4IDY A;  1WBQ A;  2EVM A;  2GG9 A;  2GGB A;  3PKD A;  5D6E A;  3PKE A;  2V3Y A;  4EGE A;  1XGM A;  4U73 A;  2NQ6 A;  4FLJ A;  4FUK A;  1XNZ A;  2BWW A;  4PV4 A;  5JFR A;  1WY2 A;  2ADU A;  2GA2 A;  2Q94 A;  2GZ5 A;  1WLR A;  4U6J A;  3MR1 A;  3L24 A;  2GG7 A;  3IG4 A;  2Q95 A;  4KM3 A;  2Q96 A;  4IEC A;  1Y1N A;  4S01 A;  4U6E A;  1PV9 A;  4U6W A;  4U75 A;  2BWX A;  5CDE A;  1YW8 A;  3PKC A;  4U76 A;  1MAT A;  4FO8 A;  1R5H A;  3IU9 A;  4ZWO A;  1C22 A;  4S2R P;  5CLS A;  4A6V A;  4IKR A;  1WN1 A;  2P9A A;  2Q8K A;  3RVA A;  2EVO A;  1XGN A;  4ZWU A;  4U71 A;  4U6Z A;  2BN7 A;  3FM3 A;  1XGS A;  2B3L A;  4ZWP A;  4R60 A;  4U70 A;  3CB5 A;  2GG3 A;  1KQ9 A;  3BIQ A;  1KQ0 A;  4U1B A;  4FLI A;  3BIT A;  2EVC A;  4IKU A;  1C23 A;  2GTX A;  5FCF A;  5E5B A;  2B3K A;  2GG2 A;  4RGZ 1;  4ZNG A;  3FMQ A;  1QXY A;  2DFI A;  4Z7M A;  4HXX A;  2EA4 A;  4FLL A;  1C21 A;  2IW2 A;  4IKS A;  4IPA A;  1BN5 A;  1C27 A;  1YJ3 A;  2GU7 A;  2GU5 A;  1YW9 A;  3CTZ A;  3TAV A;  3D27 A;  4FLK A;  1BOA A;  2BH3 A;  4FKC A;  4IF7 A;  1B59 A;  2GGC A;  1JAW A;  1XGO A;  2GG8 A;  1O0X A;  3L7G A;  4S00 A;  4RZY A;  2EA2 A;  4IU6 A;  2G6P A;  5CE6 A;  2GG5 A;  5FCH A;  2HOW A;  1N51 A;  5JI6 A;  1QZY A;  2Q92 A;  2BHC A;  2BB7 A;  3Q6D A;  1W2M A;  2GU4 A;  4OOK A;  2BWY A;  3MAT A;  5JHU A;  3IU8 A;  3ROR A;  2P99 A;  3CB6 A;  2MAT A;  3BIP A;  4QR8 A;  2BHA A;  2BWS A;  1M35 A;  5CDL A;  1W7V A;  1R58 A; 
#chains in the Genus database with same CATH topology
 2GG0 A;  1R5G A;  2NQ7 A;  3PKB A;  2BWU A;  1A16 A;  5D6F A;  5CDV A;  1QXZ A;  1YVM A;  2P98 A;  3S6B A;  2OAZ A;  4PNC A;  4U69 A;  2BWV A;  4FO7 A;  4B28 A;  2BWT A;  4U6C A;  1WL9 A;  4MAT A;  2OKN A;  5CIK A;  1C24 A;  1YW7 A;  5CNX A;  1WL6 A;  2V3X A;  1B6A A;  4JUQ A;  1QXW A;  2BHB A;  2V3Z A;  3IU7 A;  3MX6 A;  1CHM A;  2BHD A;  2ZSG A;  1KP0 A;  2B3H A;  2GU6 A;  3PKA A;  4RZZ A;  4S2T P;  1WKM A;  4IKT A;  4A6W A;  2V6C A;  2Q93 A;  3FMR A;  3TB5 A;  4IDY A;  1WBQ A;  2EVM A;  2GG9 A;  2GGB A;  3PKD A;  5D6E A;  3PKE A;  2V3Y A;  4EGE A;  1XGM A;  4U73 A;  2NQ6 A;  4FLJ A;  4FUK A;  1XNZ A;  2BWW A;  4PV4 A;  5JFR A;  1WY2 A;  2ADU A;  2GA2 A;  2Q94 A;  2GZ5 A;  1WLR A;  4U6J A;  3MR1 A;  3L24 A;  2GG7 A;  3IG4 A;  2Q95 A;  4KM3 A;  2Q96 A;  4IEC A;  1Y1N A;  4S01 A;  4U6E A;  1PV9 A;  4U6W A;  4U75 A;  2BWX A;  5CDE A;  1YW8 A;  3PKC A;  4U76 A;  1MAT A;  4FO8 A;  1R5H A;  3IU9 A;  4ZWO A;  1C22 A;  4S2R P;  5CLS A;  4A6V A;  4IKR A;  1WN1 A;  2P9A A;  2Q8K A;  3RVA A;  2EVO A;  1XGN A;  4ZWU A;  4U71 A;  4U6Z A;  2BN7 A;  3FM3 A;  1XGS A;  2B3L A;  4ZWP A;  4R60 A;  4U70 A;  3CB5 A;  2GG3 A;  1KQ9 A;  3BIQ A;  1KQ0 A;  4U1B A;  4FLI A;  3BIT A;  2EVC A;  4IKU A;  1C23 A;  2GTX A;  5FCF A;  5E5B A;  2B3K A;  2GG2 A;  4RGZ 1;  4ZNG A;  3FMQ A;  1QXY A;  2DFI A;  4Z7M A;  4HXX A;  2EA4 A;  4FLL A;  1C21 A;  2IW2 A;  4IKS A;  4IPA A;  1BN5 A;  1C27 A;  1YJ3 A;  2GU7 A;  2GU5 A;  1YW9 A;  3CTZ A;  3TAV A;  3D27 A;  4FLK A;  1BOA A;  2BH3 A;  4FKC A;  4IF7 A;  1B59 A;  2GGC A;  1JAW A;  1XGO A;  2GG8 A;  1O0X A;  3L7G A;  4S00 A;  4RZY A;  2EA2 A;  4IU6 A;  2G6P A;  5CE6 A;  2GG5 A;  5FCH A;  2HOW A;  1N51 A;  5JI6 A;  1QZY A;  2Q92 A;  2BHC A;  2BB7 A;  3Q6D A;  1W2M A;  2GU4 A;  4OOK A;  2BWY A;  3MAT A;  5JHU A;  3IU8 A;  3ROR A;  2P99 A;  3CB6 A;  2MAT A;  3BIP A;  4QR8 A;  2BHA A;  2BWS A;  1M35 A;  5CDL A;  1W7V A;  1R58 A; 
#chains in the Genus database with same CATH homology
 2GG0 A;  1R5G A;  2NQ7 A;  3PKB A;  2BWU A;  1A16 A;  5D6F A;  5CDV A;  1QXZ A;  1YVM A;  2P98 A;  3S6B A;  2OAZ A;  4PNC A;  4U69 A;  2BWV A;  4FO7 A;  4B28 A;  2BWT A;  4U6C A;  1WL9 A;  4MAT A;  2OKN A;  5CIK A;  1C24 A;  1YW7 A;  5CNX A;  1WL6 A;  2V3X A;  1B6A A;  4JUQ A;  1QXW A;  2BHB A;  2V3Z A;  3IU7 A;  3MX6 A;  1CHM A;  2BHD A;  2ZSG A;  1KP0 A;  2B3H A;  2GU6 A;  3PKA A;  4RZZ A;  4S2T P;  1WKM A;  4IKT A;  4A6W A;  2V6C A;  2Q93 A;  3FMR A;  3TB5 A;  4IDY A;  1WBQ A;  2EVM A;  2GG9 A;  2GGB A;  3PKD A;  5D6E A;  3PKE A;  2V3Y A;  4EGE A;  1XGM A;  4U73 A;  2NQ6 A;  4FLJ A;  4FUK A;  1XNZ A;  2BWW A;  4PV4 A;  5JFR A;  1WY2 A;  2ADU A;  2GA2 A;  2Q94 A;  2GZ5 A;  1WLR A;  4U6J A;  3MR1 A;  3L24 A;  2GG7 A;  3IG4 A;  2Q95 A;  4KM3 A;  2Q96 A;  4IEC A;  1Y1N A;  4S01 A;  4U6E A;  1PV9 A;  4U6W A;  4U75 A;  2BWX A;  5CDE A;  1YW8 A;  3PKC A;  4U76 A;  1MAT A;  4FO8 A;  1R5H A;  3IU9 A;  4ZWO A;  1C22 A;  4S2R P;  5CLS A;  4A6V A;  4IKR A;  1WN1 A;  2P9A A;  2Q8K A;  3RVA A;  2EVO A;  1XGN A;  4ZWU A;  4U71 A;  4U6Z A;  2BN7 A;  3FM3 A;  1XGS A;  2B3L A;  4ZWP A;  4R60 A;  4U70 A;  3CB5 A;  2GG3 A;  1KQ9 A;  3BIQ A;  1KQ0 A;  4U1B A;  4FLI A;  3BIT A;  2EVC A;  4IKU A;  1C23 A;  2GTX A;  5FCF A;  5E5B A;  2B3K A;  2GG2 A;  4RGZ 1;  4ZNG A;  3FMQ A;  1QXY A;  2DFI A;  4Z7M A;  4HXX A;  2EA4 A;  4FLL A;  1C21 A;  2IW2 A;  4IKS A;  4IPA A;  1BN5 A;  1C27 A;  1YJ3 A;  2GU7 A;  2GU5 A;  1YW9 A;  3CTZ A;  3TAV A;  3D27 A;  4FLK A;  1BOA A;  2BH3 A;  4FKC A;  4IF7 A;  1B59 A;  2GGC A;  1JAW A;  1XGO A;  2GG8 A;  1O0X A;  3L7G A;  4S00 A;  4RZY A;  2EA2 A;  4IU6 A;  2G6P A;  5CE6 A;  2GG5 A;  5FCH A;  2HOW A;  1N51 A;  5JI6 A;  1QZY A;  2Q92 A;  2BHC A;  2BB7 A;  3Q6D A;  1W2M A;  2GU4 A;  4OOK A;  2BWY A;  3MAT A;  5JHU A;  3IU8 A;  3ROR A;  2P99 A;  3CB6 A;  2MAT A;  3BIP A;  4QR8 A;  2BHA A;  2BWS A;  1M35 A;  5CDL A;  1W7V A;  1R58 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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