2BHBA

Zn substituted e. coli aminopeptidase p
Total Genus 160
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
160
sequence length
440
structure length
440
Chain Sequence
SEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPYRQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEKLGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYAYADVIVNSALEKLRKGSRQNLTAPATMIDWRPVVHEMRLFKSPEEIAVLRRAGEITAMAHTRAMEKCRPGMFEYHLEGEIHHEFNRHGARYPSYNTIVGSGENGCILHYTENECEMRDGDLVLIDAGCEYKGYAGDITRTFPVNGKFTQAQREIYDIVLESLETSLRLYRPGTSILEVTGEVVRIMVSGLVKLGILKGDVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPDAEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMVAARKQ
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structural and Functional Implications of Metal Ion Selection in Aminopeptidase P, a Metalloprotease with a Dinuclear Metal Center.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords XAA-PRO AMINOPEPTIDASE
total genus 160
structure length 440
sequence length 440
ec nomenclature ec 3.4.11.9: Xaa-Pro aminopeptidase.
pdb deposition date 2005-01-08

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF05195 AMP_N Aminopeptidase P, N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 2bhbA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 2bhbA02
3OVKA 4FKCA 1C27A 3IU8A 4S2RP 3PKDA 2GU7A 2BH3A 2BHCA 4IU6A 1R58A 2GGCA 2GU4A 1MATA 1WN1A 4ZWUA 1JAWA 1W7VA 4OOKA 3RORA 5JFRA 2GG2A 2IW2A 4IKUA 4IF7A 1C22A 3IU9A 2P99A 2MATA 4FO8A 2OKNA 3TAVA 4A6WA 1PV9A 2V3YA 1QXYA 1XGOA 2GZ5A 3MR1A 2OAZA 3MX6A 2BWYA 2V6CA 3BIPA 1YVMA 1N51A 4U6JA 2Q92A 1KP0A 5CDVA 1A16A 1XNZA 5JHUA 2GU6A 1BN5A 2GG7A 4IKTA 4ZWPA 4U1BA 4S00A 4S2TP 2B3LA 4A6VA 3S6BA 5CDEA 2GG8A 5FCHA 2Q94A 2V3XA 2BWVA 4U73A 3BIQA 1C21A 3MATA 4IDYA 5D6EA 4FLLA 2BWUA 3RVAA 1WKMA 2G6PA 1QZYA 4FLIA 1XGNA 4PNCA 4ZNGA 3BITA 4RZYA 1CHMA 1M35A 4MATA 4ZWOA 2BHAA 3FM3A 4U76A 1R5HA 1Y1NA 2Q96A 4IPAA 4HXXA 2GTXA 4IECA 2EVMA 5E2CA 2EA4A 3PKBA 2BB7A 1KQ0A 2GG0A 3IU7A 2Q93A 2ZSGA 1QXZA 4KM3A 2BWWA 4U6EA 3O5VA 4RGZ1 3CTZA 3L24A 4RZZA 2BN7A 4U71A 1KQ9A 3IL0A 1R5GA 3PKEA 4U6WA 2GA2A 4U75A 2BWTA 1WY2A 2ADUA 3D27A 3PKAA 4S01A 2EVCA 2Q95A 1WLRA 1XGSA 1C23A 2NQ7A 4U6ZA 3OOOA 1WBQA 3IG4A 2BWXA 2BHDA 2GU5A 5D6FA 2Q8KA 1YW8A 5FCFA 4B28A 1O0XA 4FO7A 4PV4A 4IKSA 2BWSA 2GG5A 3CB6A 2P98A 3PKCA 2B3HA 2BHBA 5CNXA 5JI6A 5E5BA 1WL6A 2P9AA 1XGMA 1W2MA 4U70A 1C24A 2HOWA 5CE6A 1YJ3A 1YW9A 1BOAA 2GG3A 3L7GA 4FLJA 1QXWA 4Z7MA 3TB5A 3QOCA 3Q6DA 4QR8A 3I7MA 4FUKA 1WL9A 3CB5A 3FMRA 4R60A 5CDLA 2EA2A 2GG9A 5CIKA 3FMQA 4FLKA 2EVOA 1B6AA 4U6CA 4EGEA 4JUQA 3PEBA 4U69A 5CLSA 3PN9A 4IKRA 2DFIA 2GGBA 1B59A 1YW7A 2NQ6A 2V3ZA 2B3KA
chains in the Genus database with same CATH superfamily
3OVKA 4FKCA 1C27A 3IU8A 4S2RP 3PKDA 2GU7A 2BH3A 2BHCA 4IU6A 1R58A 2GGCA 2GU4A 1MATA 1WN1A 4ZWUA 1JAWA 1W7VA 4OOKA 3RORA 5JFRA 2GG2A 2IW2A 4IKUA 4IF7A 1C22A 3IU9A 2P99A 2MATA 4FO8A 2OKNA 3TAVA 4A6WA 1PV9A 2V3YA 1QXYA 1XGOA 2GZ5A 3MR1A 2OAZA 3MX6A 2BWYA 2V6CA 3BIPA 1YVMA 1N51A 4U6JA 2Q92A 1KP0A 5CDVA 1A16A 1XNZA 5JHUA 2GU6A 1BN5A 2GG7A 4IKTA 4ZWPA 4U1BA 4S00A 4S2TP 2B3LA 4A6VA 3S6BA 5CDEA 2GG8A 5FCHA 2Q94A 2V3XA 2BWVA 4U73A 3BIQA 1C21A 3MATA 4IDYA 5D6EA 4FLLA 2BWUA 3RVAA 1WKMA 2G6PA 1QZYA 4FLIA 1XGNA 4PNCA 4ZNGA 3BITA 4RZYA 1CHMA 1M35A 4MATA 4ZWOA 2BHAA 3FM3A 4U76A 1R5HA 1Y1NA 2Q96A 4IPAA 4HXXA 2GTXA 4IECA 2EVMA 5E2CA 2EA4A 3PKBA 2BB7A 1KQ0A 2GG0A 3IU7A 2Q93A 2ZSGA 1QXZA 4KM3A 2BWWA 4U6EA 3O5VA 4RGZ1 3CTZA 3L24A 4RZZA 2BN7A 4U71A 1KQ9A 3IL0A 1R5GA 3PKEA 4U6WA 2GA2A 4U75A 2BWTA 1WY2A 2ADUA 3D27A 3PKAA 4S01A 2EVCA 2Q95A 1WLRA 1XGSA 1C23A 2NQ7A 4U6ZA 3OOOA 1WBQA 3IG4A 2BWXA 2BHDA 2GU5A 5D6FA 2Q8KA 1YW8A 5FCFA 4B28A 1O0XA 4FO7A 4PV4A 4IKSA 2BWSA 2GG5A 3CB6A 2P98A 3PKCA 2B3HA 2BHBA 5CNXA 5JI6A 5E5BA 1WL6A 2P9AA 1XGMA 1W2MA 4U70A 1C24A 2HOWA 5CE6A 1YJ3A 1YW9A 1BOAA 2GG3A 3L7GA 4FLJA 1QXWA 4Z7MA 3TB5A 3QOCA 3Q6DA 4QR8A 3I7MA 4FUKA 1WL9A 3CB5A 3FMRA 4R60A 5CDLA 2EA2A 2GG9A 5CIKA 3FMQA 4FLKA 2EVOA 1B6AA 4U6CA 4EGEA 4JUQA 3PEBA 4U69A 5CLSA 3PN9A 4IKRA 2DFIA 2GGBA 1B59A 1YW7A 2NQ6A 2V3ZA 2B3KA
chains in the Genus database with same CATH topology
3OVKA 4FKCA 1C27A 3IU8A 4S2RP 3PKDA 2GU7A 2BH3A 2BHCA 4IU6A 1R58A 2GGCA 2GU4A 1MATA 1WN1A 4ZWUA 1JAWA 1W7VA 4OOKA 3RORA 5JFRA 2GG2A 2IW2A 4IKUA 4IF7A 1C22A 3IU9A 2P99A 2MATA 4FO8A 2OKNA 3TAVA 4A6WA 1PV9A 2V3YA 1QXYA 1XGOA 2GZ5A 3MR1A 2OAZA 3MX6A 2BWYA 2V6CA 3BIPA 1YVMA 1N51A 4U6JA 2Q92A 1KP0A 5CDVA 1A16A 1XNZA 5JHUA 2GU6A 1BN5A 2GG7A 4IKTA 4ZWPA 4U1BA 4S00A 4S2TP 2B3LA 4A6VA 3S6BA 5CDEA 2GG8A 5FCHA 2Q94A 2V3XA 2BWVA 4U73A 3BIQA 1C21A 3MATA 4IDYA 5D6EA 4FLLA 2BWUA 3RVAA 1WKMA 2G6PA 1QZYA 4FLIA 1XGNA 4PNCA 4ZNGA 3BITA 4RZYA 1CHMA 1M35A 4MATA 4ZWOA 2BHAA 3FM3A 4U76A 1R5HA 1Y1NA 2Q96A 4IPAA 4HXXA 2GTXA 4IECA 2EVMA 5E2CA 2EA4A 3PKBA 2BB7A 1KQ0A 2GG0A 3IU7A 2Q93A 2ZSGA 1QXZA 4KM3A 2BWWA 4U6EA 3O5VA 4RGZ1 3CTZA 3L24A 4RZZA 2BN7A 4U71A 1KQ9A 3IL0A 1R5GA 3PKEA 4U6WA 2GA2A 4U75A 2BWTA 1WY2A 2ADUA 3D27A 3PKAA 4S01A 2EVCA 2Q95A 1WLRA 1XGSA 1C23A 2NQ7A 4U6ZA 3OOOA 1WBQA 3IG4A 2BWXA 2BHDA 2GU5A 5D6FA 2Q8KA 1YW8A 5FCFA 4B28A 1O0XA 4FO7A 4PV4A 4IKSA 2BWSA 2GG5A 3CB6A 2P98A 3PKCA 2B3HA 2BHBA 5CNXA 5JI6A 5E5BA 1WL6A 2P9AA 1XGMA 1W2MA 4U70A 1C24A 2HOWA 5CE6A 1YJ3A 1YW9A 1BOAA 2GG3A 3L7GA 4FLJA 1QXWA 4Z7MA 3TB5A 3QOCA 3Q6DA 4QR8A 3I7MA 4FUKA 1WL9A 3CB5A 3FMRA 4R60A 5CDLA 2EA2A 2GG9A 5CIKA 3FMQA 4FLKA 2EVOA 1B6AA 4U6CA 4EGEA 4JUQA 3PEBA 4U69A 5CLSA 3PN9A 4IKRA 2DFIA 2GGBA 1B59A 1YW7A 2NQ6A 2V3ZA 2B3KA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3OVK A;  4FKC A;  1C27 A;  3IU8 A;  4S2R P;  3PKD A;  2GU7 A;  2BH3 A;  2BHC A;  4IU6 A;  1R58 A;  2GGC A;  2GU4 A;  1MAT A;  1WN1 A;  4ZWU A;  1JAW A;  1W7V A;  4OOK A;  3ROR A;  5JFR A;  2GG2 A;  2IW2 A;  4IKU A;  4IF7 A;  1C22 A;  3IU9 A;  2P99 A;  2MAT A;  4FO8 A;  2OKN A;  3TAV A;  4A6W A;  1PV9 A;  2V3Y A;  1QXY A;  1XGO A;  2GZ5 A;  3MR1 A;  2OAZ A;  3MX6 A;  2BWY A;  2V6C A;  3BIP A;  1YVM A;  1N51 A;  4U6J A;  2Q92 A;  1KP0 A;  5CDV A;  1A16 A;  1XNZ A;  5JHU A;  2GU6 A;  1BN5 A;  2GG7 A;  4IKT A;  4ZWP A;  4U1B A;  4S00 A;  4S2T P;  2B3L A;  4A6V A;  3S6B A;  5CDE A;  2GG8 A;  5FCH A;  2Q94 A;  2V3X A;  2BWV A;  4U73 A;  3BIQ A;  1C21 A;  3MAT A;  4IDY A;  5D6E A;  4FLL A;  2BWU A;  3RVA A;  1WKM A;  2G6P A;  1QZY A;  4FLI A;  1XGN A;  4PNC A;  4ZNG A;  3BIT A;  4RZY A;  1CHM A;  1M35 A;  4MAT A;  4ZWO A;  2BHA A;  3FM3 A;  4U76 A;  1R5H A;  1Y1N A;  2Q96 A;  4IPA A;  4HXX A;  2GTX A;  4IEC A;  2EVM A;  5E2C A;  2EA4 A;  3PKB A;  2BB7 A;  1KQ0 A;  2GG0 A;  3IU7 A;  2Q93 A;  2ZSG A;  1QXZ A;  4KM3 A;  2BWW A;  4U6E A;  3O5V A;  4RGZ 1;  3CTZ A;  3L24 A;  4RZZ A;  2BN7 A;  4U71 A;  1KQ9 A;  3IL0 A;  1R5G A;  3PKE A;  4U6W A;  2GA2 A;  4U75 A;  2BWT A;  1WY2 A;  2ADU A;  3D27 A;  3PKA A;  4S01 A;  2EVC A;  2Q95 A;  1WLR A;  1XGS A;  1C23 A;  2NQ7 A;  4U6Z A;  3OOO A;  1WBQ A;  3IG4 A;  2BWX A;  2BHD A;  2GU5 A;  5D6F A;  2Q8K A;  1YW8 A;  5FCF A;  4B28 A;  1O0X A;  4FO7 A;  4PV4 A;  4IKS A;  2BWS A;  2GG5 A;  3CB6 A;  2P98 A;  3PKC A;  2B3H A;  2BHB A;  5CNX A;  5JI6 A;  5E5B A;  1WL6 A;  2P9A A;  1XGM A;  1W2M A;  4U70 A;  1C24 A;  2HOW A;  5CE6 A;  1YJ3 A;  1YW9 A;  1BOA A;  2GG3 A;  3L7G A;  4FLJ A;  1QXW A;  4Z7M A;  3TB5 A;  3QOC A;  3Q6D A;  4QR8 A;  3I7M A;  4FUK A;  1WL9 A;  3CB5 A;  3FMR A;  4R60 A;  5CDL A;  2EA2 A;  2GG9 A;  5CIK A;  3FMQ A;  4FLK A;  2EVO A;  1B6A A;  4U6C A;  4EGE A;  4JUQ A;  3PEB A;  4U69 A;  5CLS A;  3PN9 A;  4IKR A;  2DFI A;  2GGB A;  1B59 A;  1YW7 A;  2NQ6 A;  2V3Z A;  2B3K A; 
#chains in the Genus database with same CATH topology
 3OVK A;  4FKC A;  1C27 A;  3IU8 A;  4S2R P;  3PKD A;  2GU7 A;  2BH3 A;  2BHC A;  4IU6 A;  1R58 A;  2GGC A;  2GU4 A;  1MAT A;  1WN1 A;  4ZWU A;  1JAW A;  1W7V A;  4OOK A;  3ROR A;  5JFR A;  2GG2 A;  2IW2 A;  4IKU A;  4IF7 A;  1C22 A;  3IU9 A;  2P99 A;  2MAT A;  4FO8 A;  2OKN A;  3TAV A;  4A6W A;  1PV9 A;  2V3Y A;  1QXY A;  1XGO A;  2GZ5 A;  3MR1 A;  2OAZ A;  3MX6 A;  2BWY A;  2V6C A;  3BIP A;  1YVM A;  1N51 A;  4U6J A;  2Q92 A;  1KP0 A;  5CDV A;  1A16 A;  1XNZ A;  5JHU A;  2GU6 A;  1BN5 A;  2GG7 A;  4IKT A;  4ZWP A;  4U1B A;  4S00 A;  4S2T P;  2B3L A;  4A6V A;  3S6B A;  5CDE A;  2GG8 A;  5FCH A;  2Q94 A;  2V3X A;  2BWV A;  4U73 A;  3BIQ A;  1C21 A;  3MAT A;  4IDY A;  5D6E A;  4FLL A;  2BWU A;  3RVA A;  1WKM A;  2G6P A;  1QZY A;  4FLI A;  1XGN A;  4PNC A;  4ZNG A;  3BIT A;  4RZY A;  1CHM A;  1M35 A;  4MAT A;  4ZWO A;  2BHA A;  3FM3 A;  4U76 A;  1R5H A;  1Y1N A;  2Q96 A;  4IPA A;  4HXX A;  2GTX A;  4IEC A;  2EVM A;  5E2C A;  2EA4 A;  3PKB A;  2BB7 A;  1KQ0 A;  2GG0 A;  3IU7 A;  2Q93 A;  2ZSG A;  1QXZ A;  4KM3 A;  2BWW A;  4U6E A;  3O5V A;  4RGZ 1;  3CTZ A;  3L24 A;  4RZZ A;  2BN7 A;  4U71 A;  1KQ9 A;  3IL0 A;  1R5G A;  3PKE A;  4U6W A;  2GA2 A;  4U75 A;  2BWT A;  1WY2 A;  2ADU A;  3D27 A;  3PKA A;  4S01 A;  2EVC A;  2Q95 A;  1WLR A;  1XGS A;  1C23 A;  2NQ7 A;  4U6Z A;  3OOO A;  1WBQ A;  3IG4 A;  2BWX A;  2BHD A;  2GU5 A;  5D6F A;  2Q8K A;  1YW8 A;  5FCF A;  4B28 A;  1O0X A;  4FO7 A;  4PV4 A;  4IKS A;  2BWS A;  2GG5 A;  3CB6 A;  2P98 A;  3PKC A;  2B3H A;  2BHB A;  5CNX A;  5JI6 A;  5E5B A;  1WL6 A;  2P9A A;  1XGM A;  1W2M A;  4U70 A;  1C24 A;  2HOW A;  5CE6 A;  1YJ3 A;  1YW9 A;  1BOA A;  2GG3 A;  3L7G A;  4FLJ A;  1QXW A;  4Z7M A;  3TB5 A;  3QOC A;  3Q6D A;  4QR8 A;  3I7M A;  4FUK A;  1WL9 A;  3CB5 A;  3FMR A;  4R60 A;  5CDL A;  2EA2 A;  2GG9 A;  5CIK A;  3FMQ A;  4FLK A;  2EVO A;  1B6A A;  4U6C A;  4EGE A;  4JUQ A;  3PEB A;  4U69 A;  5CLS A;  3PN9 A;  4IKR A;  2DFI A;  2GGB A;  1B59 A;  1YW7 A;  2NQ6 A;  2V3Z A;  2B3K A; 
#chains in the Genus database with same CATH homology
 3OVK A;  4FKC A;  1C27 A;  3IU8 A;  4S2R P;  3PKD A;  2GU7 A;  2BH3 A;  2BHC A;  4IU6 A;  1R58 A;  2GGC A;  2GU4 A;  1MAT A;  1WN1 A;  4ZWU A;  1JAW A;  1W7V A;  4OOK A;  3ROR A;  5JFR A;  2GG2 A;  2IW2 A;  4IKU A;  4IF7 A;  1C22 A;  3IU9 A;  2P99 A;  2MAT A;  4FO8 A;  2OKN A;  3TAV A;  4A6W A;  1PV9 A;  2V3Y A;  1QXY A;  1XGO A;  2GZ5 A;  3MR1 A;  2OAZ A;  3MX6 A;  2BWY A;  2V6C A;  3BIP A;  1YVM A;  1N51 A;  4U6J A;  2Q92 A;  1KP0 A;  5CDV A;  1A16 A;  1XNZ A;  5JHU A;  2GU6 A;  1BN5 A;  2GG7 A;  4IKT A;  4ZWP A;  4U1B A;  4S00 A;  4S2T P;  2B3L A;  4A6V A;  3S6B A;  5CDE A;  2GG8 A;  5FCH A;  2Q94 A;  2V3X A;  2BWV A;  4U73 A;  3BIQ A;  1C21 A;  3MAT A;  4IDY A;  5D6E A;  4FLL A;  2BWU A;  3RVA A;  1WKM A;  2G6P A;  1QZY A;  4FLI A;  1XGN A;  4PNC A;  4ZNG A;  3BIT A;  4RZY A;  1CHM A;  1M35 A;  4MAT A;  4ZWO A;  2BHA A;  3FM3 A;  4U76 A;  1R5H A;  1Y1N A;  2Q96 A;  4IPA A;  4HXX A;  2GTX A;  4IEC A;  2EVM A;  5E2C A;  2EA4 A;  3PKB A;  2BB7 A;  1KQ0 A;  2GG0 A;  3IU7 A;  2Q93 A;  2ZSG A;  1QXZ A;  4KM3 A;  2BWW A;  4U6E A;  3O5V A;  4RGZ 1;  3CTZ A;  3L24 A;  4RZZ A;  2BN7 A;  4U71 A;  1KQ9 A;  3IL0 A;  1R5G A;  3PKE A;  4U6W A;  2GA2 A;  4U75 A;  2BWT A;  1WY2 A;  2ADU A;  3D27 A;  3PKA A;  4S01 A;  2EVC A;  2Q95 A;  1WLR A;  1XGS A;  1C23 A;  2NQ7 A;  4U6Z A;  3OOO A;  1WBQ A;  3IG4 A;  2BWX A;  2BHD A;  2GU5 A;  5D6F A;  2Q8K A;  1YW8 A;  5FCF A;  4B28 A;  1O0X A;  4FO7 A;  4PV4 A;  4IKS A;  2BWS A;  2GG5 A;  3CB6 A;  2P98 A;  3PKC A;  2B3H A;  2BHB A;  5CNX A;  5JI6 A;  5E5B A;  1WL6 A;  2P9A A;  1XGM A;  1W2M A;  4U70 A;  1C24 A;  2HOW A;  5CE6 A;  1YJ3 A;  1YW9 A;  1BOA A;  2GG3 A;  3L7G A;  4FLJ A;  1QXW A;  4Z7M A;  3TB5 A;  3QOC A;  3Q6D A;  4QR8 A;  3I7M A;  4FUK A;  1WL9 A;  3CB5 A;  3FMR A;  4R60 A;  5CDL A;  2EA2 A;  2GG9 A;  5CIK A;  3FMQ A;  4FLK A;  2EVO A;  1B6A A;  4U6C A;  4EGE A;  4JUQ A;  3PEB A;  4U69 A;  5CLS A;  3PN9 A;  4IKR A;  2DFI A;  2GGB A;  1B59 A;  1YW7 A;  2NQ6 A;  2V3Z A;  2B3K A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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