3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
b'PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL'
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
4U6EA 4RZZA 4FO7A 3MR1A 1W2MA 2BWSA 4IECA 3RVAA 2EA4A 5CIKA 2IW2A 2GZ5A 4PV4A 4A6WA 2P99A 4FLKA 1C24A 4U6JA 5JHUA 2BWYA 3D27A 2GU5A 4ZWPA 1C27A 4IU6A 1WBQA 2EA2A 5FCHA 1B6AA 1A16A 1JAWA 2DFIA 2EVMA 4IKSA 5CNXA 4HXXA 2GU4A 2HOWA 1YW8A 3MATA 1QZYA 3L7GA 3CTZA 4IPAA 4RZYA 4U6WA 5CDVA 2BHDA 2P98A 5E5BA 1BN5A 1MATA 4ZWOA 1XGOA 1WN1A 2G6PA 5JFRA 2GG2A 2BH3A 2B3KA 4S00A 2GU7A 3PKDA 1R5HA 1YVMA 2BHBA 2Q93A 1C22A 3FM3A 4S2RP 2EVCA 3MX6A 4U6CA 2B3LA 3BIPA 4IDYA 1B59A 1KQ9A 3L24A 1W7VA 4EGEA 2GG9A 2V6CA 3PKAA 2BB7A 1WLRA 2BWXA 1O0XA 3PKBA 4FKCA 4OOKA 4FO8A 1R5GA 2P9AA 5D6EA 2GG3A 1PV9A 1C23A 2GG7A 1XGMA 4U70A 3PKCA 1YJ3A 3FMQA 5CDLA 1YW9A 1C21A 2MATA 2Q95A 1QXWA 1KQ0A 2V3ZA 3CB5A 2BWUA 1QXYA 1WKMA 1N51A 2EVOA 3FMRA 1XGSA 1R58A 4U73A 2GG0A 3Q6DA 2ZSGA 4MATA 5D6FA 4A6VA 2BHCA 4Z7MA 2GA2A 4QR8A 2BN7A 2NQ7A 1M35A 1XGNA 2BWTA 4JUQA 5CLSA 3S6BA 3PKEA 5CDEA 1KP0A 4B28A 2GU6A 3IU9A 3IU8A 2V3YA 4PNCA 2GG8A 4KM3A 3RORA 4IKRA 5FCFA 2GG5A 3CB6A 4S01A 2Q8KA 1WL6A 1Y1NA 2Q94A 3TAVA 4RGZ1 4S2TP 4U76A 1WL9A 2Q96A 4IKTA 2NQ6A 3IU7A 1YW7A 5JI6A 5CE6A 4FLIA 4U75A 2V3XA 2OAZA 4U71A 3BIQA 3IG4A 4FLLA 4FLJA 4IKUA 2BWVA 2BHAA 4R60A 4U69A 4ZNGA 2B3HA 4ZWUA 2OKNA 1BOAA 3BITA 1CHMA 1QXZA 4FUKA 2Q92A 4U1BA 2GGBA 2BWWA 4IF7A 2ADUA 1XNZA 3TB5A 2GGCA 4U6ZA 1WY2A 2GTXA
chains in the Genus database with same CATH superfamily
4U6EA 4RZZA 4FO7A 3MR1A 1W2MA 2BWSA 4IECA 3RVAA 2EA4A 5CIKA 2IW2A 2GZ5A 4PV4A 4A6WA 2P99A 4FLKA 1C24A 4U6JA 5JHUA 2BWYA 3D27A 2GU5A 4ZWPA 1C27A 4IU6A 1WBQA 2EA2A 5FCHA 1B6AA 1A16A 1JAWA 2DFIA 2EVMA 4IKSA 5CNXA 4HXXA 2GU4A 2HOWA 1YW8A 3MATA 1QZYA 3L7GA 3CTZA 4IPAA 4RZYA 4U6WA 5CDVA 2BHDA 2P98A 5E5BA 1BN5A 1MATA 4ZWOA 1XGOA 1WN1A 2G6PA 5JFRA 2GG2A 2BH3A 2B3KA 4S00A 2GU7A 3PKDA 1R5HA 1YVMA 2BHBA 2Q93A 1C22A 3FM3A 4S2RP 2EVCA 3MX6A 4U6CA 2B3LA 3BIPA 4IDYA 1B59A 1KQ9A 3L24A 1W7VA 4EGEA 2GG9A 2V6CA 3PKAA 2BB7A 1WLRA 2BWXA 1O0XA 3PKBA 4FKCA 4OOKA 4FO8A 1R5GA 2P9AA 5D6EA 2GG3A 1PV9A 1C23A 2GG7A 1XGMA 4U70A 3PKCA 1YJ3A 3FMQA 5CDLA 1YW9A 1C21A 2MATA 2Q95A 1QXWA 1KQ0A 2V3ZA 3CB5A 2BWUA 1QXYA 1WKMA 1N51A 2EVOA 3FMRA 1XGSA 1R58A 4U73A 2GG0A 3Q6DA 2ZSGA 4MATA 5D6FA 4A6VA 2BHCA 4Z7MA 2GA2A 4QR8A 2BN7A 2NQ7A 1M35A 1XGNA 2BWTA 4JUQA 5CLSA 3S6BA 3PKEA 5CDEA 1KP0A 4B28A 2GU6A 3IU9A 3IU8A 2V3YA 4PNCA 2GG8A 4KM3A 3RORA 4IKRA 5FCFA 2GG5A 3CB6A 4S01A 2Q8KA 1WL6A 1Y1NA 2Q94A 3TAVA 4RGZ1 4S2TP 4U76A 1WL9A 2Q96A 4IKTA 2NQ6A 3IU7A 1YW7A 5JI6A 5CE6A 4FLIA 4U75A 2V3XA 2OAZA 4U71A 3BIQA 3IG4A 4FLLA 4FLJA 4IKUA 2BWVA 2BHAA 4R60A 4U69A 4ZNGA 2B3HA 4ZWUA 2OKNA 1BOAA 3BITA 1CHMA 1QXZA 4FUKA 2Q92A 4U1BA 2GGBA 2BWWA 4IF7A 2ADUA 1XNZA 3TB5A 2GGCA 4U6ZA 1WY2A 2GTXA
chains in the Genus database with same CATH topology
4U6EA 4RZZA 4FO7A 3MR1A 1W2MA 2BWSA 4IECA 3RVAA 2EA4A 5CIKA 2IW2A 2GZ5A 4PV4A 4A6WA 2P99A 4FLKA 1C24A 4U6JA 5JHUA 2BWYA 3D27A 2GU5A 4ZWPA 1C27A 4IU6A 1WBQA 2EA2A 5FCHA 1B6AA 1A16A 1JAWA 2DFIA 2EVMA 4IKSA 5CNXA 4HXXA 2GU4A 2HOWA 1YW8A 3MATA 1QZYA 3L7GA 3CTZA 4IPAA 4RZYA 4U6WA 5CDVA 2BHDA 2P98A 5E5BA 1BN5A 1MATA 4ZWOA 1XGOA 1WN1A 2G6PA 5JFRA 2GG2A 2BH3A 2B3KA 4S00A 2GU7A 3PKDA 1R5HA 1YVMA 2BHBA 2Q93A 1C22A 3FM3A 4S2RP 2EVCA 3MX6A 4U6CA 2B3LA 3BIPA 4IDYA 1B59A 1KQ9A 3L24A 1W7VA 4EGEA 2GG9A 2V6CA 3PKAA 2BB7A 1WLRA 2BWXA 1O0XA 3PKBA 4FKCA 4OOKA 4FO8A 1R5GA 2P9AA 5D6EA 2GG3A 1PV9A 1C23A 2GG7A 1XGMA 4U70A 3PKCA 1YJ3A 3FMQA 5CDLA 1YW9A 1C21A 2MATA 2Q95A 1QXWA 1KQ0A 2V3ZA 3CB5A 2BWUA 1QXYA 1WKMA 1N51A 2EVOA 3FMRA 1XGSA 1R58A 4U73A 2GG0A 3Q6DA 2ZSGA 4MATA 5D6FA 4A6VA 2BHCA 4Z7MA 2GA2A 4QR8A 2BN7A 2NQ7A 1M35A 1XGNA 2BWTA 4JUQA 5CLSA 3S6BA 3PKEA 5CDEA 1KP0A 4B28A 2GU6A 3IU9A 3IU8A 2V3YA 4PNCA 2GG8A 4KM3A 3RORA 4IKRA 5FCFA 2GG5A 3CB6A 4S01A 2Q8KA 1WL6A 1Y1NA 2Q94A 3TAVA 4RGZ1 4S2TP 4U76A 1WL9A 2Q96A 4IKTA 2NQ6A 3IU7A 1YW7A 5JI6A 5CE6A 4FLIA 4U75A 2V3XA 2OAZA 4U71A 3BIQA 3IG4A 4FLLA 4FLJA 4IKUA 2BWVA 2BHAA 4R60A 4U69A 4ZNGA 2B3HA 4ZWUA 2OKNA 1BOAA 3BITA 1CHMA 1QXZA 4FUKA 2Q92A 4U1BA 2GGBA 2BWWA 4IF7A 2ADUA 1XNZA 3TB5A 2GGCA 4U6ZA 1WY2A 2GTXA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6E A;  4RZZ A;  4FO7 A;  3MR1 A;  1W2M A;  2BWS A;  4IEC A;  3RVA A;  2EA4 A;  5CIK A;  2IW2 A;  2GZ5 A;  4PV4 A;  4A6W A;  2P99 A;  4FLK A;  1C24 A;  4U6J A;  5JHU A;  2BWY A;  3D27 A;  2GU5 A;  4ZWP A;  1C27 A;  4IU6 A;  1WBQ A;  2EA2 A;  5FCH A;  1B6A A;  1A16 A;  1JAW A;  2DFI A;  2EVM A;  4IKS A;  5CNX A;  4HXX A;  2GU4 A;  2HOW A;  1YW8 A;  3MAT A;  1QZY A;  3L7G A;  3CTZ A;  4IPA A;  4RZY A;  4U6W A;  5CDV A;  2BHD A;  2P98 A;  5E5B A;  1BN5 A;  1MAT A;  4ZWO A;  1XGO A;  1WN1 A;  2G6P A;  5JFR A;  2GG2 A;  2BH3 A;  2B3K A;  4S00 A;  2GU7 A;  3PKD A;  1R5H A;  1YVM A;  2BHB A;  2Q93 A;  1C22 A;  3FM3 A;  4S2R P;  2EVC A;  3MX6 A;  4U6C A;  2B3L A;  3BIP A;  4IDY A;  1B59 A;  1KQ9 A;  3L24 A;  1W7V A;  4EGE A;  2GG9 A;  2V6C A;  3PKA A;  2BB7 A;  1WLR A;  2BWX A;  1O0X A;  3PKB A;  4FKC A;  4OOK A;  4FO8 A;  1R5G A;  2P9A A;  5D6E A;  2GG3 A;  1PV9 A;  1C23 A;  2GG7 A;  1XGM A;  4U70 A;  3PKC A;  1YJ3 A;  3FMQ A;  5CDL A;  1YW9 A;  1C21 A;  2MAT A;  2Q95 A;  1QXW A;  1KQ0 A;  2V3Z A;  3CB5 A;  2BWU A;  1QXY A;  1WKM A;  1N51 A;  2EVO A;  3FMR A;  1XGS A;  1R58 A;  4U73 A;  2GG0 A;  3Q6D A;  2ZSG A;  4MAT A;  5D6F A;  4A6V A;  2BHC A;  4Z7M A;  2GA2 A;  4QR8 A;  2BN7 A;  2NQ7 A;  1M35 A;  1XGN A;  2BWT A;  4JUQ A;  5CLS A;  3S6B A;  3PKE A;  5CDE A;  1KP0 A;  4B28 A;  2GU6 A;  3IU9 A;  3IU8 A;  2V3Y A;  4PNC A;  2GG8 A;  4KM3 A;  3ROR A;  4IKR A;  5FCF A;  2GG5 A;  3CB6 A;  4S01 A;  2Q8K A;  1WL6 A;  1Y1N A;  2Q94 A;  3TAV A;  4RGZ 1;  4S2T P;  4U76 A;  1WL9 A;  2Q96 A;  4IKT A;  2NQ6 A;  3IU7 A;  1YW7 A;  5JI6 A;  5CE6 A;  4FLI A;  4U75 A;  2V3X A;  2OAZ A;  4U71 A;  3BIQ A;  3IG4 A;  4FLL A;  4FLJ A;  4IKU A;  2BWV A;  2BHA A;  4R60 A;  4U69 A;  4ZNG A;  2B3H A;  4ZWU A;  2OKN A;  1BOA A;  3BIT A;  1CHM A;  1QXZ A;  4FUK A;  2Q92 A;  4U1B A;  2GGB A;  2BWW A;  4IF7 A;  2ADU A;  1XNZ A;  3TB5 A;  2GGC A;  4U6Z A;  1WY2 A;  2GTX A; 
#chains in the Genus database with same CATH topology
 4U6E A;  4RZZ A;  4FO7 A;  3MR1 A;  1W2M A;  2BWS A;  4IEC A;  3RVA A;  2EA4 A;  5CIK A;  2IW2 A;  2GZ5 A;  4PV4 A;  4A6W A;  2P99 A;  4FLK A;  1C24 A;  4U6J A;  5JHU A;  2BWY A;  3D27 A;  2GU5 A;  4ZWP A;  1C27 A;  4IU6 A;  1WBQ A;  2EA2 A;  5FCH A;  1B6A A;  1A16 A;  1JAW A;  2DFI A;  2EVM A;  4IKS A;  5CNX A;  4HXX A;  2GU4 A;  2HOW A;  1YW8 A;  3MAT A;  1QZY A;  3L7G A;  3CTZ A;  4IPA A;  4RZY A;  4U6W A;  5CDV A;  2BHD A;  2P98 A;  5E5B A;  1BN5 A;  1MAT A;  4ZWO A;  1XGO A;  1WN1 A;  2G6P A;  5JFR A;  2GG2 A;  2BH3 A;  2B3K A;  4S00 A;  2GU7 A;  3PKD A;  1R5H A;  1YVM A;  2BHB A;  2Q93 A;  1C22 A;  3FM3 A;  4S2R P;  2EVC A;  3MX6 A;  4U6C A;  2B3L A;  3BIP A;  4IDY A;  1B59 A;  1KQ9 A;  3L24 A;  1W7V A;  4EGE A;  2GG9 A;  2V6C A;  3PKA A;  2BB7 A;  1WLR A;  2BWX A;  1O0X A;  3PKB A;  4FKC A;  4OOK A;  4FO8 A;  1R5G A;  2P9A A;  5D6E A;  2GG3 A;  1PV9 A;  1C23 A;  2GG7 A;  1XGM A;  4U70 A;  3PKC A;  1YJ3 A;  3FMQ A;  5CDL A;  1YW9 A;  1C21 A;  2MAT A;  2Q95 A;  1QXW A;  1KQ0 A;  2V3Z A;  3CB5 A;  2BWU A;  1QXY A;  1WKM A;  1N51 A;  2EVO A;  3FMR A;  1XGS A;  1R58 A;  4U73 A;  2GG0 A;  3Q6D A;  2ZSG A;  4MAT A;  5D6F A;  4A6V A;  2BHC A;  4Z7M A;  2GA2 A;  4QR8 A;  2BN7 A;  2NQ7 A;  1M35 A;  1XGN A;  2BWT A;  4JUQ A;  5CLS A;  3S6B A;  3PKE A;  5CDE A;  1KP0 A;  4B28 A;  2GU6 A;  3IU9 A;  3IU8 A;  2V3Y A;  4PNC A;  2GG8 A;  4KM3 A;  3ROR A;  4IKR A;  5FCF A;  2GG5 A;  3CB6 A;  4S01 A;  2Q8K A;  1WL6 A;  1Y1N A;  2Q94 A;  3TAV A;  4RGZ 1;  4S2T P;  4U76 A;  1WL9 A;  2Q96 A;  4IKT A;  2NQ6 A;  3IU7 A;  1YW7 A;  5JI6 A;  5CE6 A;  4FLI A;  4U75 A;  2V3X A;  2OAZ A;  4U71 A;  3BIQ A;  3IG4 A;  4FLL A;  4FLJ A;  4IKU A;  2BWV A;  2BHA A;  4R60 A;  4U69 A;  4ZNG A;  2B3H A;  4ZWU A;  2OKN A;  1BOA A;  3BIT A;  1CHM A;  1QXZ A;  4FUK A;  2Q92 A;  4U1B A;  2GGB A;  2BWW A;  4IF7 A;  2ADU A;  1XNZ A;  3TB5 A;  2GGC A;  4U6Z A;  1WY2 A;  2GTX A; 
#chains in the Genus database with same CATH homology
 4U6E A;  4RZZ A;  4FO7 A;  3MR1 A;  1W2M A;  2BWS A;  4IEC A;  3RVA A;  2EA4 A;  5CIK A;  2IW2 A;  2GZ5 A;  4PV4 A;  4A6W A;  2P99 A;  4FLK A;  1C24 A;  4U6J A;  5JHU A;  2BWY A;  3D27 A;  2GU5 A;  4ZWP A;  1C27 A;  4IU6 A;  1WBQ A;  2EA2 A;  5FCH A;  1B6A A;  1A16 A;  1JAW A;  2DFI A;  2EVM A;  4IKS A;  5CNX A;  4HXX A;  2GU4 A;  2HOW A;  1YW8 A;  3MAT A;  1QZY A;  3L7G A;  3CTZ A;  4IPA A;  4RZY A;  4U6W A;  5CDV A;  2BHD A;  2P98 A;  5E5B A;  1BN5 A;  1MAT A;  4ZWO A;  1XGO A;  1WN1 A;  2G6P A;  5JFR A;  2GG2 A;  2BH3 A;  2B3K A;  4S00 A;  2GU7 A;  3PKD A;  1R5H A;  1YVM A;  2BHB A;  2Q93 A;  1C22 A;  3FM3 A;  4S2R P;  2EVC A;  3MX6 A;  4U6C A;  2B3L A;  3BIP A;  4IDY A;  1B59 A;  1KQ9 A;  3L24 A;  1W7V A;  4EGE A;  2GG9 A;  2V6C A;  3PKA A;  2BB7 A;  1WLR A;  2BWX A;  1O0X A;  3PKB A;  4FKC A;  4OOK A;  4FO8 A;  1R5G A;  2P9A A;  5D6E A;  2GG3 A;  1PV9 A;  1C23 A;  2GG7 A;  1XGM A;  4U70 A;  3PKC A;  1YJ3 A;  3FMQ A;  5CDL A;  1YW9 A;  1C21 A;  2MAT A;  2Q95 A;  1QXW A;  1KQ0 A;  2V3Z A;  3CB5 A;  2BWU A;  1QXY A;  1WKM A;  1N51 A;  2EVO A;  3FMR A;  1XGS A;  1R58 A;  4U73 A;  2GG0 A;  3Q6D A;  2ZSG A;  4MAT A;  5D6F A;  4A6V A;  2BHC A;  4Z7M A;  2GA2 A;  4QR8 A;  2BN7 A;  2NQ7 A;  1M35 A;  1XGN A;  2BWT A;  4JUQ A;  5CLS A;  3S6B A;  3PKE A;  5CDE A;  1KP0 A;  4B28 A;  2GU6 A;  3IU9 A;  3IU8 A;  2V3Y A;  4PNC A;  2GG8 A;  4KM3 A;  3ROR A;  4IKR A;  5FCF A;  2GG5 A;  3CB6 A;  4S01 A;  2Q8K A;  1WL6 A;  1Y1N A;  2Q94 A;  3TAV A;  4RGZ 1;  4S2T P;  4U76 A;  1WL9 A;  2Q96 A;  4IKT A;  2NQ6 A;  3IU7 A;  1YW7 A;  5JI6 A;  5CE6 A;  4FLI A;  4U75 A;  2V3X A;  2OAZ A;  4U71 A;  3BIQ A;  3IG4 A;  4FLL A;  4FLJ A;  4IKU A;  2BWV A;  2BHA A;  4R60 A;  4U69 A;  4ZNG A;  2B3H A;  4ZWU A;  2OKN A;  1BOA A;  3BIT A;  1CHM A;  1QXZ A;  4FUK A;  2Q92 A;  4U1B A;  2GGB A;  2BWW A;  4IF7 A;  2ADU A;  1XNZ A;  3TB5 A;  2GGC A;  4U6Z A;  1WY2 A;  2GTX A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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