3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
4IKTA 4S00A 2Q94A 2Q96A 2GG7A 1B59A 4ZWPA 1C23A 4HXXA 4U71A 3PKEA 4IPAA 4PNCA 4FUKA 4U1BA 3FMRA 4U73A 2V3YA 1W2MA 1WN1A 2GU7A 4A6VA 3MR1A 4PV4A 2GGCA 1C24A 3BITA 2Q92A 4S2TP 4QR8A 1YJ3A 1KP0A 3S6BA 2OKNA 4IECA 2Q95A 4U70A 2Q93A 3MATA 1WL9A 1BOAA 1WY2A 3FM3A 2Q8KA 4FLJA 2BB7A 2NQ7A 4IKUA 2B3LA 2GG9A 4U6JA 1PV9A 2GA2A 3PKCA 1XNZA 2BWYA 5JHUA 5D6FA 3PKDA 2BWTA 5CLSA 1JAWA 2HOWA 4B28A 2V6CA 1YVMA 2GG0A 4U6ZA 3MX6A 2MATA 2B3KA 2DFIA 2BWUA 2BWWA 3BIPA 1WLRA 2V3XA 4A6WA 1QXZA 2BH3A 2ADUA 1Y1NA 1O0XA 4FLLA 3TAVA 4U75A 1WKMA 2EVOA 2GG8A 3IU8A 3CB5A 5D6EA 1YW8A 1XGMA 1N51A 3IU7A 1B6AA 2GU6A 2BHBA 4FO8A 4U69A 2G6PA 3RORA 4FO7A 2P9AA 1M35A 2EA4A 4IF7A 5CIKA 1R5HA 3FMQA 3RVAA 2GZ5A 2BN7A 2GG5A 3L7GA 1R5GA 4MATA 2BHAA 2P99A 4U6CA 2GG3A 1C22A 4IKRA 2GG2A 5JI6A 2EA2A 5FCHA 4ZNGA 2IW2A 3PKBA 5CDVA 4FLKA 2BHDA 2EVCA 4RZYA 1XGOA 4RZZA 3IG4A 5CNXA 5FCFA 3L24A 1A16A 5JFRA 1XGSA 1YW7A 4KM3A 5CDEA 3TB5A 1BN5A 2BWVA 3PKAA 4ZWOA 2OAZA 1KQ0A 4U6WA 4U76A 4FKCA 1KQ9A 3Q6DA 3CB6A 4Z7MA 2GU4A 5E5BA 4R60A 5CE6A 1WBQA 4RGZ1 4IU6A 1XGNA 1WL6A 4OOKA 1QXYA 3D27A 3CTZA 1C21A 4FLIA 2BWXA 2GTXA 2V3ZA 4IKSA 1QZYA 2GU5A 4S2RP 4S01A 2BHCA 1R58A 1CHMA 2BWSA 2GGBA 4JUQA 5CDLA 2ZSGA 1MATA 3IU9A 4ZWUA 2B3HA 4EGEA 2NQ6A 2P98A 4IDYA 1C27A 4U6EA 1QXWA 1W7VA 3BIQA 1YW9A 2EVMA
chains in the Genus database with same CATH superfamily
4IKTA 4S00A 2Q94A 2Q96A 2GG7A 1B59A 4ZWPA 1C23A 4HXXA 4U71A 3PKEA 4IPAA 4PNCA 4FUKA 4U1BA 3FMRA 4U73A 2V3YA 1W2MA 1WN1A 2GU7A 4A6VA 3MR1A 4PV4A 2GGCA 1C24A 3BITA 2Q92A 4S2TP 4QR8A 1YJ3A 1KP0A 3S6BA 2OKNA 4IECA 2Q95A 4U70A 2Q93A 3MATA 1WL9A 1BOAA 1WY2A 3FM3A 2Q8KA 4FLJA 2BB7A 2NQ7A 4IKUA 2B3LA 2GG9A 4U6JA 1PV9A 2GA2A 3PKCA 1XNZA 2BWYA 5JHUA 5D6FA 3PKDA 2BWTA 5CLSA 1JAWA 2HOWA 4B28A 2V6CA 1YVMA 2GG0A 4U6ZA 3MX6A 2MATA 2B3KA 2DFIA 2BWUA 2BWWA 3BIPA 1WLRA 2V3XA 4A6WA 1QXZA 2BH3A 2ADUA 1Y1NA 1O0XA 4FLLA 3TAVA 4U75A 1WKMA 2EVOA 2GG8A 3IU8A 3CB5A 5D6EA 1YW8A 1XGMA 1N51A 3IU7A 1B6AA 2GU6A 2BHBA 4FO8A 4U69A 2G6PA 3RORA 4FO7A 2P9AA 1M35A 2EA4A 4IF7A 5CIKA 1R5HA 3FMQA 3RVAA 2GZ5A 2BN7A 2GG5A 3L7GA 1R5GA 4MATA 2BHAA 2P99A 4U6CA 2GG3A 1C22A 4IKRA 2GG2A 5JI6A 2EA2A 5FCHA 4ZNGA 2IW2A 3PKBA 5CDVA 4FLKA 2BHDA 2EVCA 4RZYA 1XGOA 4RZZA 3IG4A 5CNXA 5FCFA 3L24A 1A16A 5JFRA 1XGSA 1YW7A 4KM3A 5CDEA 3TB5A 1BN5A 2BWVA 3PKAA 4ZWOA 2OAZA 1KQ0A 4U6WA 4U76A 4FKCA 1KQ9A 3Q6DA 3CB6A 4Z7MA 2GU4A 5E5BA 4R60A 5CE6A 1WBQA 4RGZ1 4IU6A 1XGNA 1WL6A 4OOKA 1QXYA 3D27A 3CTZA 1C21A 4FLIA 2BWXA 2GTXA 2V3ZA 4IKSA 1QZYA 2GU5A 4S2RP 4S01A 2BHCA 1R58A 1CHMA 2BWSA 2GGBA 4JUQA 5CDLA 2ZSGA 1MATA 3IU9A 4ZWUA 2B3HA 4EGEA 2NQ6A 2P98A 4IDYA 1C27A 4U6EA 1QXWA 1W7VA 3BIQA 1YW9A 2EVMA
chains in the Genus database with same CATH topology
4IKTA 4S00A 2Q94A 2Q96A 2GG7A 1B59A 4ZWPA 1C23A 4HXXA 4U71A 3PKEA 4IPAA 4PNCA 4FUKA 4U1BA 3FMRA 4U73A 2V3YA 1W2MA 1WN1A 2GU7A 4A6VA 3MR1A 4PV4A 2GGCA 1C24A 3BITA 2Q92A 4S2TP 4QR8A 1YJ3A 1KP0A 3S6BA 2OKNA 4IECA 2Q95A 4U70A 2Q93A 3MATA 1WL9A 1BOAA 1WY2A 3FM3A 2Q8KA 4FLJA 2BB7A 2NQ7A 4IKUA 2B3LA 2GG9A 4U6JA 1PV9A 2GA2A 3PKCA 1XNZA 2BWYA 5JHUA 5D6FA 3PKDA 2BWTA 5CLSA 1JAWA 2HOWA 4B28A 2V6CA 1YVMA 2GG0A 4U6ZA 3MX6A 2MATA 2B3KA 2DFIA 2BWUA 2BWWA 3BIPA 1WLRA 2V3XA 4A6WA 1QXZA 2BH3A 2ADUA 1Y1NA 1O0XA 4FLLA 3TAVA 4U75A 1WKMA 2EVOA 2GG8A 3IU8A 3CB5A 5D6EA 1YW8A 1XGMA 1N51A 3IU7A 1B6AA 2GU6A 2BHBA 4FO8A 4U69A 2G6PA 3RORA 4FO7A 2P9AA 1M35A 2EA4A 4IF7A 5CIKA 1R5HA 3FMQA 3RVAA 2GZ5A 2BN7A 2GG5A 3L7GA 1R5GA 4MATA 2BHAA 2P99A 4U6CA 2GG3A 1C22A 4IKRA 2GG2A 5JI6A 2EA2A 5FCHA 4ZNGA 2IW2A 3PKBA 5CDVA 4FLKA 2BHDA 2EVCA 4RZYA 1XGOA 4RZZA 3IG4A 5CNXA 5FCFA 3L24A 1A16A 5JFRA 1XGSA 1YW7A 4KM3A 5CDEA 3TB5A 1BN5A 2BWVA 3PKAA 4ZWOA 2OAZA 1KQ0A 4U6WA 4U76A 4FKCA 1KQ9A 3Q6DA 3CB6A 4Z7MA 2GU4A 5E5BA 4R60A 5CE6A 1WBQA 4RGZ1 4IU6A 1XGNA 1WL6A 4OOKA 1QXYA 3D27A 3CTZA 1C21A 4FLIA 2BWXA 2GTXA 2V3ZA 4IKSA 1QZYA 2GU5A 4S2RP 4S01A 2BHCA 1R58A 1CHMA 2BWSA 2GGBA 4JUQA 5CDLA 2ZSGA 1MATA 3IU9A 4ZWUA 2B3HA 4EGEA 2NQ6A 2P98A 4IDYA 1C27A 4U6EA 1QXWA 1W7VA 3BIQA 1YW9A 2EVMA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4IKT A;  4S00 A;  2Q94 A;  2Q96 A;  2GG7 A;  1B59 A;  4ZWP A;  1C23 A;  4HXX A;  4U71 A;  3PKE A;  4IPA A;  4PNC A;  4FUK A;  4U1B A;  3FMR A;  4U73 A;  2V3Y A;  1W2M A;  1WN1 A;  2GU7 A;  4A6V A;  3MR1 A;  4PV4 A;  2GGC A;  1C24 A;  3BIT A;  2Q92 A;  4S2T P;  4QR8 A;  1YJ3 A;  1KP0 A;  3S6B A;  2OKN A;  4IEC A;  2Q95 A;  4U70 A;  2Q93 A;  3MAT A;  1WL9 A;  1BOA A;  1WY2 A;  3FM3 A;  2Q8K A;  4FLJ A;  2BB7 A;  2NQ7 A;  4IKU A;  2B3L A;  2GG9 A;  4U6J A;  1PV9 A;  2GA2 A;  3PKC A;  1XNZ A;  2BWY A;  5JHU A;  5D6F A;  3PKD A;  2BWT A;  5CLS A;  1JAW A;  2HOW A;  4B28 A;  2V6C A;  1YVM A;  2GG0 A;  4U6Z A;  3MX6 A;  2MAT A;  2B3K A;  2DFI A;  2BWU A;  2BWW A;  3BIP A;  1WLR A;  2V3X A;  4A6W A;  1QXZ A;  2BH3 A;  2ADU A;  1Y1N A;  1O0X A;  4FLL A;  3TAV A;  4U75 A;  1WKM A;  2EVO A;  2GG8 A;  3IU8 A;  3CB5 A;  5D6E A;  1YW8 A;  1XGM A;  1N51 A;  3IU7 A;  1B6A A;  2GU6 A;  2BHB A;  4FO8 A;  4U69 A;  2G6P A;  3ROR A;  4FO7 A;  2P9A A;  1M35 A;  2EA4 A;  4IF7 A;  5CIK A;  1R5H A;  3FMQ A;  3RVA A;  2GZ5 A;  2BN7 A;  2GG5 A;  3L7G A;  1R5G A;  4MAT A;  2BHA A;  2P99 A;  4U6C A;  2GG3 A;  1C22 A;  4IKR A;  2GG2 A;  5JI6 A;  2EA2 A;  5FCH A;  4ZNG A;  2IW2 A;  3PKB A;  5CDV A;  4FLK A;  2BHD A;  2EVC A;  4RZY A;  1XGO A;  4RZZ A;  3IG4 A;  5CNX A;  5FCF A;  3L24 A;  1A16 A;  5JFR A;  1XGS A;  1YW7 A;  4KM3 A;  5CDE A;  3TB5 A;  1BN5 A;  2BWV A;  3PKA A;  4ZWO A;  2OAZ A;  1KQ0 A;  4U6W A;  4U76 A;  4FKC A;  1KQ9 A;  3Q6D A;  3CB6 A;  4Z7M A;  2GU4 A;  5E5B A;  4R60 A;  5CE6 A;  1WBQ A;  4RGZ 1;  4IU6 A;  1XGN A;  1WL6 A;  4OOK A;  1QXY A;  3D27 A;  3CTZ A;  1C21 A;  4FLI A;  2BWX A;  2GTX A;  2V3Z A;  4IKS A;  1QZY A;  2GU5 A;  4S2R P;  4S01 A;  2BHC A;  1R58 A;  1CHM A;  2BWS A;  2GGB A;  4JUQ A;  5CDL A;  2ZSG A;  1MAT A;  3IU9 A;  4ZWU A;  2B3H A;  4EGE A;  2NQ6 A;  2P98 A;  4IDY A;  1C27 A;  4U6E A;  1QXW A;  1W7V A;  3BIQ A;  1YW9 A;  2EVM A; 
#chains in the Genus database with same CATH topology
 4IKT A;  4S00 A;  2Q94 A;  2Q96 A;  2GG7 A;  1B59 A;  4ZWP A;  1C23 A;  4HXX A;  4U71 A;  3PKE A;  4IPA A;  4PNC A;  4FUK A;  4U1B A;  3FMR A;  4U73 A;  2V3Y A;  1W2M A;  1WN1 A;  2GU7 A;  4A6V A;  3MR1 A;  4PV4 A;  2GGC A;  1C24 A;  3BIT A;  2Q92 A;  4S2T P;  4QR8 A;  1YJ3 A;  1KP0 A;  3S6B A;  2OKN A;  4IEC A;  2Q95 A;  4U70 A;  2Q93 A;  3MAT A;  1WL9 A;  1BOA A;  1WY2 A;  3FM3 A;  2Q8K A;  4FLJ A;  2BB7 A;  2NQ7 A;  4IKU A;  2B3L A;  2GG9 A;  4U6J A;  1PV9 A;  2GA2 A;  3PKC A;  1XNZ A;  2BWY A;  5JHU A;  5D6F A;  3PKD A;  2BWT A;  5CLS A;  1JAW A;  2HOW A;  4B28 A;  2V6C A;  1YVM A;  2GG0 A;  4U6Z A;  3MX6 A;  2MAT A;  2B3K A;  2DFI A;  2BWU A;  2BWW A;  3BIP A;  1WLR A;  2V3X A;  4A6W A;  1QXZ A;  2BH3 A;  2ADU A;  1Y1N A;  1O0X A;  4FLL A;  3TAV A;  4U75 A;  1WKM A;  2EVO A;  2GG8 A;  3IU8 A;  3CB5 A;  5D6E A;  1YW8 A;  1XGM A;  1N51 A;  3IU7 A;  1B6A A;  2GU6 A;  2BHB A;  4FO8 A;  4U69 A;  2G6P A;  3ROR A;  4FO7 A;  2P9A A;  1M35 A;  2EA4 A;  4IF7 A;  5CIK A;  1R5H A;  3FMQ A;  3RVA A;  2GZ5 A;  2BN7 A;  2GG5 A;  3L7G A;  1R5G A;  4MAT A;  2BHA A;  2P99 A;  4U6C A;  2GG3 A;  1C22 A;  4IKR A;  2GG2 A;  5JI6 A;  2EA2 A;  5FCH A;  4ZNG A;  2IW2 A;  3PKB A;  5CDV A;  4FLK A;  2BHD A;  2EVC A;  4RZY A;  1XGO A;  4RZZ A;  3IG4 A;  5CNX A;  5FCF A;  3L24 A;  1A16 A;  5JFR A;  1XGS A;  1YW7 A;  4KM3 A;  5CDE A;  3TB5 A;  1BN5 A;  2BWV A;  3PKA A;  4ZWO A;  2OAZ A;  1KQ0 A;  4U6W A;  4U76 A;  4FKC A;  1KQ9 A;  3Q6D A;  3CB6 A;  4Z7M A;  2GU4 A;  5E5B A;  4R60 A;  5CE6 A;  1WBQ A;  4RGZ 1;  4IU6 A;  1XGN A;  1WL6 A;  4OOK A;  1QXY A;  3D27 A;  3CTZ A;  1C21 A;  4FLI A;  2BWX A;  2GTX A;  2V3Z A;  4IKS A;  1QZY A;  2GU5 A;  4S2R P;  4S01 A;  2BHC A;  1R58 A;  1CHM A;  2BWS A;  2GGB A;  4JUQ A;  5CDL A;  2ZSG A;  1MAT A;  3IU9 A;  4ZWU A;  2B3H A;  4EGE A;  2NQ6 A;  2P98 A;  4IDY A;  1C27 A;  4U6E A;  1QXW A;  1W7V A;  3BIQ A;  1YW9 A;  2EVM A; 
#chains in the Genus database with same CATH homology
 4IKT A;  4S00 A;  2Q94 A;  2Q96 A;  2GG7 A;  1B59 A;  4ZWP A;  1C23 A;  4HXX A;  4U71 A;  3PKE A;  4IPA A;  4PNC A;  4FUK A;  4U1B A;  3FMR A;  4U73 A;  2V3Y A;  1W2M A;  1WN1 A;  2GU7 A;  4A6V A;  3MR1 A;  4PV4 A;  2GGC A;  1C24 A;  3BIT A;  2Q92 A;  4S2T P;  4QR8 A;  1YJ3 A;  1KP0 A;  3S6B A;  2OKN A;  4IEC A;  2Q95 A;  4U70 A;  2Q93 A;  3MAT A;  1WL9 A;  1BOA A;  1WY2 A;  3FM3 A;  2Q8K A;  4FLJ A;  2BB7 A;  2NQ7 A;  4IKU A;  2B3L A;  2GG9 A;  4U6J A;  1PV9 A;  2GA2 A;  3PKC A;  1XNZ A;  2BWY A;  5JHU A;  5D6F A;  3PKD A;  2BWT A;  5CLS A;  1JAW A;  2HOW A;  4B28 A;  2V6C A;  1YVM A;  2GG0 A;  4U6Z A;  3MX6 A;  2MAT A;  2B3K A;  2DFI A;  2BWU A;  2BWW A;  3BIP A;  1WLR A;  2V3X A;  4A6W A;  1QXZ A;  2BH3 A;  2ADU A;  1Y1N A;  1O0X A;  4FLL A;  3TAV A;  4U75 A;  1WKM A;  2EVO A;  2GG8 A;  3IU8 A;  3CB5 A;  5D6E A;  1YW8 A;  1XGM A;  1N51 A;  3IU7 A;  1B6A A;  2GU6 A;  2BHB A;  4FO8 A;  4U69 A;  2G6P A;  3ROR A;  4FO7 A;  2P9A A;  1M35 A;  2EA4 A;  4IF7 A;  5CIK A;  1R5H A;  3FMQ A;  3RVA A;  2GZ5 A;  2BN7 A;  2GG5 A;  3L7G A;  1R5G A;  4MAT A;  2BHA A;  2P99 A;  4U6C A;  2GG3 A;  1C22 A;  4IKR A;  2GG2 A;  5JI6 A;  2EA2 A;  5FCH A;  4ZNG A;  2IW2 A;  3PKB A;  5CDV A;  4FLK A;  2BHD A;  2EVC A;  4RZY A;  1XGO A;  4RZZ A;  3IG4 A;  5CNX A;  5FCF A;  3L24 A;  1A16 A;  5JFR A;  1XGS A;  1YW7 A;  4KM3 A;  5CDE A;  3TB5 A;  1BN5 A;  2BWV A;  3PKA A;  4ZWO A;  2OAZ A;  1KQ0 A;  4U6W A;  4U76 A;  4FKC A;  1KQ9 A;  3Q6D A;  3CB6 A;  4Z7M A;  2GU4 A;  5E5B A;  4R60 A;  5CE6 A;  1WBQ A;  4RGZ 1;  4IU6 A;  1XGN A;  1WL6 A;  4OOK A;  1QXY A;  3D27 A;  3CTZ A;  1C21 A;  4FLI A;  2BWX A;  2GTX A;  2V3Z A;  4IKS A;  1QZY A;  2GU5 A;  4S2R P;  4S01 A;  2BHC A;  1R58 A;  1CHM A;  2BWS A;  2GGB A;  4JUQ A;  5CDL A;  2ZSG A;  1MAT A;  3IU9 A;  4ZWU A;  2B3H A;  4EGE A;  2NQ6 A;  2P98 A;  4IDY A;  1C27 A;  4U6E A;  1QXW A;  1W7V A;  3BIQ A;  1YW9 A;  2EVM A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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