3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
2GGBA 4IPAA 4MATA 4U6JA 2BWWA 3FMRA 3IU7A 2BHAA 3L7GA 3PKAA 2EVOA 2BHDA 3CB6A 3PKEA 2Q8KA 1B6AA 2GZ5A 2EVMA 3PKBA 4S01A 4S00A 3IG4A 5JHUA 2BWXA 2ZSGA 1WLRA 2B3KA 4IKRA 4R60A 1YVMA 4RZYA 2GG8A 3RVAA 2GU5A 3Q6DA 4OOKA 5CIKA 5CDLA 2OAZA 2BB7A 4HXXA 4IDYA 1C23A 5FCFA 2EA4A 2GG2A 5FCHA 3MX6A 2BWVA 1C22A 3BIPA 2P99A 4U69A 4U6CA 3S6BA 2GA2A 3PKCA 1QZYA 1BOAA 2GG7A 4U73A 4U6ZA 4Z7MA 4FLLA 5CLSA 3D27A 3CB5A 5D6FA 3TAVA 1XNZA 4IKSA 3IU9A 4JUQA 2ADUA 2Q93A 1QXYA 5CNXA 5D6EA 4QR8A 4B28A 2EA2A 1YW8A 1KP0A 3BIQA 4IKTA 1KQ0A 4RGZ1 1CHMA 2V3YA 2BHBA 1C27A 1B59A 1WN1A 2EVCA 2MATA 1WBQA 1JAWA 4U76A 1R5GA 3FM3A 3TB5A 3BITA 4FUKA 2GGCA 5CDEA 2Q92A 2GU7A 4FLKA 4FO7A 4FO8A 1C24A 2Q95A 1W7VA 5CE6A 1BN5A 1WL9A 2IW2A 4A6WA 3L24A 1YW7A 3MR1A 3FMQA 2HOWA 2GU4A 4U6EA 2NQ7A 5E5BA 1C21A 2Q94A 2BWUA 4ZNGA 2GG0A 2V6CA 2B3HA 4IU6A 4PV4A 2BWSA 4U70A 1WL6A 1YW9A 4U75A 3IU8A 1MATA 2BWTA 2GG5A 1XGSA 2P98A 4IKUA 3RORA 4IF7A 1PV9A 1QXZA 3MATA 4FLIA 4EGEA 1M35A 1KQ9A 2G6PA 2NQ6A 5CDVA 1XGNA 2P9AA 4FKCA 1W2MA 5JI6A 2B3LA 2OKNA 2GTXA 4U1BA 5JFRA 1QXWA 4ZWOA 1XGOA 4ZWPA 4PNCA 2DFIA 1N51A 2Q96A 2GU6A 4ZWUA 1O0XA 2BHCA 1WY2A 4KM3A 4S2TP 2V3ZA 4S2RP 1A16A 2BH3A 2BWYA 1YJ3A 4IECA 2GG3A 1WKMA 1Y1NA 2BN7A 1XGMA 4U6WA 4FLJA 2GG9A 1R58A 3CTZA 4RZZA 3PKDA 2V3XA 4A6VA 4U71A 1R5HA
chains in the Genus database with same CATH superfamily
2GGBA 4IPAA 4MATA 4U6JA 2BWWA 3FMRA 3IU7A 2BHAA 3L7GA 3PKAA 2EVOA 2BHDA 3CB6A 3PKEA 2Q8KA 1B6AA 2GZ5A 2EVMA 3PKBA 4S01A 4S00A 3IG4A 5JHUA 2BWXA 2ZSGA 1WLRA 2B3KA 4IKRA 4R60A 1YVMA 4RZYA 2GG8A 3RVAA 2GU5A 3Q6DA 4OOKA 5CIKA 5CDLA 2OAZA 2BB7A 4HXXA 4IDYA 1C23A 5FCFA 2EA4A 2GG2A 5FCHA 3MX6A 2BWVA 1C22A 3BIPA 2P99A 4U69A 4U6CA 3S6BA 2GA2A 3PKCA 1QZYA 1BOAA 2GG7A 4U73A 4U6ZA 4Z7MA 4FLLA 5CLSA 3D27A 3CB5A 5D6FA 3TAVA 1XNZA 4IKSA 3IU9A 4JUQA 2ADUA 2Q93A 1QXYA 5CNXA 5D6EA 4QR8A 4B28A 2EA2A 1YW8A 1KP0A 3BIQA 4IKTA 1KQ0A 4RGZ1 1CHMA 2V3YA 2BHBA 1C27A 1B59A 1WN1A 2EVCA 2MATA 1WBQA 1JAWA 4U76A 1R5GA 3FM3A 3TB5A 3BITA 4FUKA 2GGCA 5CDEA 2Q92A 2GU7A 4FLKA 4FO7A 4FO8A 1C24A 2Q95A 1W7VA 5CE6A 1BN5A 1WL9A 2IW2A 4A6WA 3L24A 1YW7A 3MR1A 3FMQA 2HOWA 2GU4A 4U6EA 2NQ7A 5E5BA 1C21A 2Q94A 2BWUA 4ZNGA 2GG0A 2V6CA 2B3HA 4IU6A 4PV4A 2BWSA 4U70A 1WL6A 1YW9A 4U75A 3IU8A 1MATA 2BWTA 2GG5A 1XGSA 2P98A 4IKUA 3RORA 4IF7A 1PV9A 1QXZA 3MATA 4FLIA 4EGEA 1M35A 1KQ9A 2G6PA 2NQ6A 5CDVA 1XGNA 2P9AA 4FKCA 1W2MA 5JI6A 2B3LA 2OKNA 2GTXA 4U1BA 5JFRA 1QXWA 4ZWOA 1XGOA 4ZWPA 4PNCA 2DFIA 1N51A 2Q96A 2GU6A 4ZWUA 1O0XA 2BHCA 1WY2A 4KM3A 4S2TP 2V3ZA 4S2RP 1A16A 2BH3A 2BWYA 1YJ3A 4IECA 2GG3A 1WKMA 1Y1NA 2BN7A 1XGMA 4U6WA 4FLJA 2GG9A 1R58A 3CTZA 4RZZA 3PKDA 2V3XA 4A6VA 4U71A 1R5HA
chains in the Genus database with same CATH topology
2GGBA 4IPAA 4MATA 4U6JA 2BWWA 3FMRA 3IU7A 2BHAA 3L7GA 3PKAA 2EVOA 2BHDA 3CB6A 3PKEA 2Q8KA 1B6AA 2GZ5A 2EVMA 3PKBA 4S01A 4S00A 3IG4A 5JHUA 2BWXA 2ZSGA 1WLRA 2B3KA 4IKRA 4R60A 1YVMA 4RZYA 2GG8A 3RVAA 2GU5A 3Q6DA 4OOKA 5CIKA 5CDLA 2OAZA 2BB7A 4HXXA 4IDYA 1C23A 5FCFA 2EA4A 2GG2A 5FCHA 3MX6A 2BWVA 1C22A 3BIPA 2P99A 4U69A 4U6CA 3S6BA 2GA2A 3PKCA 1QZYA 1BOAA 2GG7A 4U73A 4U6ZA 4Z7MA 4FLLA 5CLSA 3D27A 3CB5A 5D6FA 3TAVA 1XNZA 4IKSA 3IU9A 4JUQA 2ADUA 2Q93A 1QXYA 5CNXA 5D6EA 4QR8A 4B28A 2EA2A 1YW8A 1KP0A 3BIQA 4IKTA 1KQ0A 4RGZ1 1CHMA 2V3YA 2BHBA 1C27A 1B59A 1WN1A 2EVCA 2MATA 1WBQA 1JAWA 4U76A 1R5GA 3FM3A 3TB5A 3BITA 4FUKA 2GGCA 5CDEA 2Q92A 2GU7A 4FLKA 4FO7A 4FO8A 1C24A 2Q95A 1W7VA 5CE6A 1BN5A 1WL9A 2IW2A 4A6WA 3L24A 1YW7A 3MR1A 3FMQA 2HOWA 2GU4A 4U6EA 2NQ7A 5E5BA 1C21A 2Q94A 2BWUA 4ZNGA 2GG0A 2V6CA 2B3HA 4IU6A 4PV4A 2BWSA 4U70A 1WL6A 1YW9A 4U75A 3IU8A 1MATA 2BWTA 2GG5A 1XGSA 2P98A 4IKUA 3RORA 4IF7A 1PV9A 1QXZA 3MATA 4FLIA 4EGEA 1M35A 1KQ9A 2G6PA 2NQ6A 5CDVA 1XGNA 2P9AA 4FKCA 1W2MA 5JI6A 2B3LA 2OKNA 2GTXA 4U1BA 5JFRA 1QXWA 4ZWOA 1XGOA 4ZWPA 4PNCA 2DFIA 1N51A 2Q96A 2GU6A 4ZWUA 1O0XA 2BHCA 1WY2A 4KM3A 4S2TP 2V3ZA 4S2RP 1A16A 2BH3A 2BWYA 1YJ3A 4IECA 2GG3A 1WKMA 1Y1NA 2BN7A 1XGMA 4U6WA 4FLJA 2GG9A 1R58A 3CTZA 4RZZA 3PKDA 2V3XA 4A6VA 4U71A 1R5HA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GGB A;  4IPA A;  4MAT A;  4U6J A;  2BWW A;  3FMR A;  3IU7 A;  2BHA A;  3L7G A;  3PKA A;  2EVO A;  2BHD A;  3CB6 A;  3PKE A;  2Q8K A;  1B6A A;  2GZ5 A;  2EVM A;  3PKB A;  4S01 A;  4S00 A;  3IG4 A;  5JHU A;  2BWX A;  2ZSG A;  1WLR A;  2B3K A;  4IKR A;  4R60 A;  1YVM A;  4RZY A;  2GG8 A;  3RVA A;  2GU5 A;  3Q6D A;  4OOK A;  5CIK A;  5CDL A;  2OAZ A;  2BB7 A;  4HXX A;  4IDY A;  1C23 A;  5FCF A;  2EA4 A;  2GG2 A;  5FCH A;  3MX6 A;  2BWV A;  1C22 A;  3BIP A;  2P99 A;  4U69 A;  4U6C A;  3S6B A;  2GA2 A;  3PKC A;  1QZY A;  1BOA A;  2GG7 A;  4U73 A;  4U6Z A;  4Z7M A;  4FLL A;  5CLS A;  3D27 A;  3CB5 A;  5D6F A;  3TAV A;  1XNZ A;  4IKS A;  3IU9 A;  4JUQ A;  2ADU A;  2Q93 A;  1QXY A;  5CNX A;  5D6E A;  4QR8 A;  4B28 A;  2EA2 A;  1YW8 A;  1KP0 A;  3BIQ A;  4IKT A;  1KQ0 A;  4RGZ 1;  1CHM A;  2V3Y A;  2BHB A;  1C27 A;  1B59 A;  1WN1 A;  2EVC A;  2MAT A;  1WBQ A;  1JAW A;  4U76 A;  1R5G A;  3FM3 A;  3TB5 A;  3BIT A;  4FUK A;  2GGC A;  5CDE A;  2Q92 A;  2GU7 A;  4FLK A;  4FO7 A;  4FO8 A;  1C24 A;  2Q95 A;  1W7V A;  5CE6 A;  1BN5 A;  1WL9 A;  2IW2 A;  4A6W A;  3L24 A;  1YW7 A;  3MR1 A;  3FMQ A;  2HOW A;  2GU4 A;  4U6E A;  2NQ7 A;  5E5B A;  1C21 A;  2Q94 A;  2BWU A;  4ZNG A;  2GG0 A;  2V6C A;  2B3H A;  4IU6 A;  4PV4 A;  2BWS A;  4U70 A;  1WL6 A;  1YW9 A;  4U75 A;  3IU8 A;  1MAT A;  2BWT A;  2GG5 A;  1XGS A;  2P98 A;  4IKU A;  3ROR A;  4IF7 A;  1PV9 A;  1QXZ A;  3MAT A;  4FLI A;  4EGE A;  1M35 A;  1KQ9 A;  2G6P A;  2NQ6 A;  5CDV A;  1XGN A;  2P9A A;  4FKC A;  1W2M A;  5JI6 A;  2B3L A;  2OKN A;  2GTX A;  4U1B A;  5JFR A;  1QXW A;  4ZWO A;  1XGO A;  4ZWP A;  4PNC A;  2DFI A;  1N51 A;  2Q96 A;  2GU6 A;  4ZWU A;  1O0X A;  2BHC A;  1WY2 A;  4KM3 A;  4S2T P;  2V3Z A;  4S2R P;  1A16 A;  2BH3 A;  2BWY A;  1YJ3 A;  4IEC A;  2GG3 A;  1WKM A;  1Y1N A;  2BN7 A;  1XGM A;  4U6W A;  4FLJ A;  2GG9 A;  1R58 A;  3CTZ A;  4RZZ A;  3PKD A;  2V3X A;  4A6V A;  4U71 A;  1R5H A; 
#chains in the Genus database with same CATH topology
 2GGB A;  4IPA A;  4MAT A;  4U6J A;  2BWW A;  3FMR A;  3IU7 A;  2BHA A;  3L7G A;  3PKA A;  2EVO A;  2BHD A;  3CB6 A;  3PKE A;  2Q8K A;  1B6A A;  2GZ5 A;  2EVM A;  3PKB A;  4S01 A;  4S00 A;  3IG4 A;  5JHU A;  2BWX A;  2ZSG A;  1WLR A;  2B3K A;  4IKR A;  4R60 A;  1YVM A;  4RZY A;  2GG8 A;  3RVA A;  2GU5 A;  3Q6D A;  4OOK A;  5CIK A;  5CDL A;  2OAZ A;  2BB7 A;  4HXX A;  4IDY A;  1C23 A;  5FCF A;  2EA4 A;  2GG2 A;  5FCH A;  3MX6 A;  2BWV A;  1C22 A;  3BIP A;  2P99 A;  4U69 A;  4U6C A;  3S6B A;  2GA2 A;  3PKC A;  1QZY A;  1BOA A;  2GG7 A;  4U73 A;  4U6Z A;  4Z7M A;  4FLL A;  5CLS A;  3D27 A;  3CB5 A;  5D6F A;  3TAV A;  1XNZ A;  4IKS A;  3IU9 A;  4JUQ A;  2ADU A;  2Q93 A;  1QXY A;  5CNX A;  5D6E A;  4QR8 A;  4B28 A;  2EA2 A;  1YW8 A;  1KP0 A;  3BIQ A;  4IKT A;  1KQ0 A;  4RGZ 1;  1CHM A;  2V3Y A;  2BHB A;  1C27 A;  1B59 A;  1WN1 A;  2EVC A;  2MAT A;  1WBQ A;  1JAW A;  4U76 A;  1R5G A;  3FM3 A;  3TB5 A;  3BIT A;  4FUK A;  2GGC A;  5CDE A;  2Q92 A;  2GU7 A;  4FLK A;  4FO7 A;  4FO8 A;  1C24 A;  2Q95 A;  1W7V A;  5CE6 A;  1BN5 A;  1WL9 A;  2IW2 A;  4A6W A;  3L24 A;  1YW7 A;  3MR1 A;  3FMQ A;  2HOW A;  2GU4 A;  4U6E A;  2NQ7 A;  5E5B A;  1C21 A;  2Q94 A;  2BWU A;  4ZNG A;  2GG0 A;  2V6C A;  2B3H A;  4IU6 A;  4PV4 A;  2BWS A;  4U70 A;  1WL6 A;  1YW9 A;  4U75 A;  3IU8 A;  1MAT A;  2BWT A;  2GG5 A;  1XGS A;  2P98 A;  4IKU A;  3ROR A;  4IF7 A;  1PV9 A;  1QXZ A;  3MAT A;  4FLI A;  4EGE A;  1M35 A;  1KQ9 A;  2G6P A;  2NQ6 A;  5CDV A;  1XGN A;  2P9A A;  4FKC A;  1W2M A;  5JI6 A;  2B3L A;  2OKN A;  2GTX A;  4U1B A;  5JFR A;  1QXW A;  4ZWO A;  1XGO A;  4ZWP A;  4PNC A;  2DFI A;  1N51 A;  2Q96 A;  2GU6 A;  4ZWU A;  1O0X A;  2BHC A;  1WY2 A;  4KM3 A;  4S2T P;  2V3Z A;  4S2R P;  1A16 A;  2BH3 A;  2BWY A;  1YJ3 A;  4IEC A;  2GG3 A;  1WKM A;  1Y1N A;  2BN7 A;  1XGM A;  4U6W A;  4FLJ A;  2GG9 A;  1R58 A;  3CTZ A;  4RZZ A;  3PKD A;  2V3X A;  4A6V A;  4U71 A;  1R5H A; 
#chains in the Genus database with same CATH homology
 2GGB A;  4IPA A;  4MAT A;  4U6J A;  2BWW A;  3FMR A;  3IU7 A;  2BHA A;  3L7G A;  3PKA A;  2EVO A;  2BHD A;  3CB6 A;  3PKE A;  2Q8K A;  1B6A A;  2GZ5 A;  2EVM A;  3PKB A;  4S01 A;  4S00 A;  3IG4 A;  5JHU A;  2BWX A;  2ZSG A;  1WLR A;  2B3K A;  4IKR A;  4R60 A;  1YVM A;  4RZY A;  2GG8 A;  3RVA A;  2GU5 A;  3Q6D A;  4OOK A;  5CIK A;  5CDL A;  2OAZ A;  2BB7 A;  4HXX A;  4IDY A;  1C23 A;  5FCF A;  2EA4 A;  2GG2 A;  5FCH A;  3MX6 A;  2BWV A;  1C22 A;  3BIP A;  2P99 A;  4U69 A;  4U6C A;  3S6B A;  2GA2 A;  3PKC A;  1QZY A;  1BOA A;  2GG7 A;  4U73 A;  4U6Z A;  4Z7M A;  4FLL A;  5CLS A;  3D27 A;  3CB5 A;  5D6F A;  3TAV A;  1XNZ A;  4IKS A;  3IU9 A;  4JUQ A;  2ADU A;  2Q93 A;  1QXY A;  5CNX A;  5D6E A;  4QR8 A;  4B28 A;  2EA2 A;  1YW8 A;  1KP0 A;  3BIQ A;  4IKT A;  1KQ0 A;  4RGZ 1;  1CHM A;  2V3Y A;  2BHB A;  1C27 A;  1B59 A;  1WN1 A;  2EVC A;  2MAT A;  1WBQ A;  1JAW A;  4U76 A;  1R5G A;  3FM3 A;  3TB5 A;  3BIT A;  4FUK A;  2GGC A;  5CDE A;  2Q92 A;  2GU7 A;  4FLK A;  4FO7 A;  4FO8 A;  1C24 A;  2Q95 A;  1W7V A;  5CE6 A;  1BN5 A;  1WL9 A;  2IW2 A;  4A6W A;  3L24 A;  1YW7 A;  3MR1 A;  3FMQ A;  2HOW A;  2GU4 A;  4U6E A;  2NQ7 A;  5E5B A;  1C21 A;  2Q94 A;  2BWU A;  4ZNG A;  2GG0 A;  2V6C A;  2B3H A;  4IU6 A;  4PV4 A;  2BWS A;  4U70 A;  1WL6 A;  1YW9 A;  4U75 A;  3IU8 A;  1MAT A;  2BWT A;  2GG5 A;  1XGS A;  2P98 A;  4IKU A;  3ROR A;  4IF7 A;  1PV9 A;  1QXZ A;  3MAT A;  4FLI A;  4EGE A;  1M35 A;  1KQ9 A;  2G6P A;  2NQ6 A;  5CDV A;  1XGN A;  2P9A A;  4FKC A;  1W2M A;  5JI6 A;  2B3L A;  2OKN A;  2GTX A;  4U1B A;  5JFR A;  1QXW A;  4ZWO A;  1XGO A;  4ZWP A;  4PNC A;  2DFI A;  1N51 A;  2Q96 A;  2GU6 A;  4ZWU A;  1O0X A;  2BHC A;  1WY2 A;  4KM3 A;  4S2T P;  2V3Z A;  4S2R P;  1A16 A;  2BH3 A;  2BWY A;  1YJ3 A;  4IEC A;  2GG3 A;  1WKM A;  1Y1N A;  2BN7 A;  1XGM A;  4U6W A;  4FLJ A;  2GG9 A;  1R58 A;  3CTZ A;  4RZZ A;  3PKD A;  2V3X A;  4A6V A;  4U71 A;  1R5H A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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