3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
1XGOA 4IPAA 3MATA 1N51A 4Z7MA 1QXZA 3Q6DA 3RVAA 2OKNA 2Q93A 1KQ9A 2V3XA 1CHMA 1QZYA 2Q96A 4RGZ1 1XGNA 2GU4A 5E5BA 1XGMA 5CIKA 1BOAA 3FM3A 4FKCA 4FLIA 4FLJA 4QR8A 4PNCA 2BH3A 1R5HA 1C27A 2GA2A 5CE6A 2B3LA 2GU5A 2BWXA 4EGEA 1PV9A 2Q8KA 2B3HA 1WKMA 4U6WA 2BN7A 3FMQA 3TB5A 1Y1NA 4U76A 2BHDA 2BWYA 1YW9A 1C22A 1W7VA 4U6EA 3D27A 2GGBA 1W2MA 3CB6A 1KQ0A 4IKRA 3BIPA 3TAVA 4IKSA 4ZWOA 1BN5A 1MATA 2BWSA 5D6FA 3PKEA 2BHBA 4S2RP 5JFRA 2Q94A 4IF7A 2EVOA 1B59A 4U75A 4U6CA 2V6CA 3L7GA 3CB5A 4IKTA 2BWVA 1WLRA 2GG3A 4U73A 1R58A 4IDYA 4S01A 1WY2A 2ZSGA 4S2TP 5CDLA 2GG0A 1YW8A 2GG8A 2G6PA 1QXYA 4IKUA 2GGCA 1KP0A 2GU6A 2P9AA 2OAZA 3IU8A 4ZWPA 1WN1A 2EVMA 2P99A 3IU9A 2BWUA 4U71A 3PKDA 4RZYA 1JAWA 2EVCA 4R60A 1QXWA 2BHAA 1A16A 2GU7A 3FMRA 2IW2A 2P98A 1XGSA 4FUKA 3S6BA 1M35A 1YW7A 1WL9A 2NQ7A 5CNXA 4U6ZA 2GTXA 5FCHA 1R5GA 3BIQA 4HXXA 4FLKA 3MR1A 2DFIA 2BWTA 3PKBA 3PKCA 1C23A 5FCFA 2ADUA 5D6EA 5JI6A 2GZ5A 2GG5A 5JHUA 2HOWA 2MATA 2GG7A 2Q92A 4IU6A 3PKAA 1O0XA 5CDEA 2GG9A 1XNZA 4FO8A 1WBQA 4OOKA 4U1BA 2BHCA 2EA4A 4PV4A 4S00A 4MATA 1C21A 3CTZA 4IECA 4KM3A 2Q95A 4FO7A 4U70A 3BITA 4A6WA 4ZNGA 3IU7A 4A6VA 4ZWUA 1YJ3A 2B3KA 2V3ZA 4RZZA 4B28A 2EA2A 2V3YA 2BB7A 3RORA 1B6AA 3MX6A 4U6JA 1YVMA 2GG2A 1C24A 2BWWA 4U69A 4FLLA 2NQ6A 3L24A 5CDVA 3IG4A 5CLSA 4JUQA 1WL6A
chains in the Genus database with same CATH superfamily
1XGOA 4IPAA 3MATA 1N51A 4Z7MA 1QXZA 3Q6DA 3RVAA 2OKNA 2Q93A 1KQ9A 2V3XA 1CHMA 1QZYA 2Q96A 4RGZ1 1XGNA 2GU4A 5E5BA 1XGMA 5CIKA 1BOAA 3FM3A 4FKCA 4FLIA 4FLJA 4QR8A 4PNCA 2BH3A 1R5HA 1C27A 2GA2A 5CE6A 2B3LA 2GU5A 2BWXA 4EGEA 1PV9A 2Q8KA 2B3HA 1WKMA 4U6WA 2BN7A 3FMQA 3TB5A 1Y1NA 4U76A 2BHDA 2BWYA 1YW9A 1C22A 1W7VA 4U6EA 3D27A 2GGBA 1W2MA 3CB6A 1KQ0A 4IKRA 3BIPA 3TAVA 4IKSA 4ZWOA 1BN5A 1MATA 2BWSA 5D6FA 3PKEA 2BHBA 4S2RP 5JFRA 2Q94A 4IF7A 2EVOA 1B59A 4U75A 4U6CA 2V6CA 3L7GA 3CB5A 4IKTA 2BWVA 1WLRA 2GG3A 4U73A 1R58A 4IDYA 4S01A 1WY2A 2ZSGA 4S2TP 5CDLA 2GG0A 1YW8A 2GG8A 2G6PA 1QXYA 4IKUA 2GGCA 1KP0A 2GU6A 2P9AA 2OAZA 3IU8A 4ZWPA 1WN1A 2EVMA 2P99A 3IU9A 2BWUA 4U71A 3PKDA 4RZYA 1JAWA 2EVCA 4R60A 1QXWA 2BHAA 1A16A 2GU7A 3FMRA 2IW2A 2P98A 1XGSA 4FUKA 3S6BA 1M35A 1YW7A 1WL9A 2NQ7A 5CNXA 4U6ZA 2GTXA 5FCHA 1R5GA 3BIQA 4HXXA 4FLKA 3MR1A 2DFIA 2BWTA 3PKBA 3PKCA 1C23A 5FCFA 2ADUA 5D6EA 5JI6A 2GZ5A 2GG5A 5JHUA 2HOWA 2MATA 2GG7A 2Q92A 4IU6A 3PKAA 1O0XA 5CDEA 2GG9A 1XNZA 4FO8A 1WBQA 4OOKA 4U1BA 2BHCA 2EA4A 4PV4A 4S00A 4MATA 1C21A 3CTZA 4IECA 4KM3A 2Q95A 4FO7A 4U70A 3BITA 4A6WA 4ZNGA 3IU7A 4A6VA 4ZWUA 1YJ3A 2B3KA 2V3ZA 4RZZA 4B28A 2EA2A 2V3YA 2BB7A 3RORA 1B6AA 3MX6A 4U6JA 1YVMA 2GG2A 1C24A 2BWWA 4U69A 4FLLA 2NQ6A 3L24A 5CDVA 3IG4A 5CLSA 4JUQA 1WL6A
chains in the Genus database with same CATH topology
1XGOA 4IPAA 3MATA 1N51A 4Z7MA 1QXZA 3Q6DA 3RVAA 2OKNA 2Q93A 1KQ9A 2V3XA 1CHMA 1QZYA 2Q96A 4RGZ1 1XGNA 2GU4A 5E5BA 1XGMA 5CIKA 1BOAA 3FM3A 4FKCA 4FLIA 4FLJA 4QR8A 4PNCA 2BH3A 1R5HA 1C27A 2GA2A 5CE6A 2B3LA 2GU5A 2BWXA 4EGEA 1PV9A 2Q8KA 2B3HA 1WKMA 4U6WA 2BN7A 3FMQA 3TB5A 1Y1NA 4U76A 2BHDA 2BWYA 1YW9A 1C22A 1W7VA 4U6EA 3D27A 2GGBA 1W2MA 3CB6A 1KQ0A 4IKRA 3BIPA 3TAVA 4IKSA 4ZWOA 1BN5A 1MATA 2BWSA 5D6FA 3PKEA 2BHBA 4S2RP 5JFRA 2Q94A 4IF7A 2EVOA 1B59A 4U75A 4U6CA 2V6CA 3L7GA 3CB5A 4IKTA 2BWVA 1WLRA 2GG3A 4U73A 1R58A 4IDYA 4S01A 1WY2A 2ZSGA 4S2TP 5CDLA 2GG0A 1YW8A 2GG8A 2G6PA 1QXYA 4IKUA 2GGCA 1KP0A 2GU6A 2P9AA 2OAZA 3IU8A 4ZWPA 1WN1A 2EVMA 2P99A 3IU9A 2BWUA 4U71A 3PKDA 4RZYA 1JAWA 2EVCA 4R60A 1QXWA 2BHAA 1A16A 2GU7A 3FMRA 2IW2A 2P98A 1XGSA 4FUKA 3S6BA 1M35A 1YW7A 1WL9A 2NQ7A 5CNXA 4U6ZA 2GTXA 5FCHA 1R5GA 3BIQA 4HXXA 4FLKA 3MR1A 2DFIA 2BWTA 3PKBA 3PKCA 1C23A 5FCFA 2ADUA 5D6EA 5JI6A 2GZ5A 2GG5A 5JHUA 2HOWA 2MATA 2GG7A 2Q92A 4IU6A 3PKAA 1O0XA 5CDEA 2GG9A 1XNZA 4FO8A 1WBQA 4OOKA 4U1BA 2BHCA 2EA4A 4PV4A 4S00A 4MATA 1C21A 3CTZA 4IECA 4KM3A 2Q95A 4FO7A 4U70A 3BITA 4A6WA 4ZNGA 3IU7A 4A6VA 4ZWUA 1YJ3A 2B3KA 2V3ZA 4RZZA 4B28A 2EA2A 2V3YA 2BB7A 3RORA 1B6AA 3MX6A 4U6JA 1YVMA 2GG2A 1C24A 2BWWA 4U69A 4FLLA 2NQ6A 3L24A 5CDVA 3IG4A 5CLSA 4JUQA 1WL6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1XGO A;  4IPA A;  3MAT A;  1N51 A;  4Z7M A;  1QXZ A;  3Q6D A;  3RVA A;  2OKN A;  2Q93 A;  1KQ9 A;  2V3X A;  1CHM A;  1QZY A;  2Q96 A;  4RGZ 1;  1XGN A;  2GU4 A;  5E5B A;  1XGM A;  5CIK A;  1BOA A;  3FM3 A;  4FKC A;  4FLI A;  4FLJ A;  4QR8 A;  4PNC A;  2BH3 A;  1R5H A;  1C27 A;  2GA2 A;  5CE6 A;  2B3L A;  2GU5 A;  2BWX A;  4EGE A;  1PV9 A;  2Q8K A;  2B3H A;  1WKM A;  4U6W A;  2BN7 A;  3FMQ A;  3TB5 A;  1Y1N A;  4U76 A;  2BHD A;  2BWY A;  1YW9 A;  1C22 A;  1W7V A;  4U6E A;  3D27 A;  2GGB A;  1W2M A;  3CB6 A;  1KQ0 A;  4IKR A;  3BIP A;  3TAV A;  4IKS A;  4ZWO A;  1BN5 A;  1MAT A;  2BWS A;  5D6F A;  3PKE A;  2BHB A;  4S2R P;  5JFR A;  2Q94 A;  4IF7 A;  2EVO A;  1B59 A;  4U75 A;  4U6C A;  2V6C A;  3L7G A;  3CB5 A;  4IKT A;  2BWV A;  1WLR A;  2GG3 A;  4U73 A;  1R58 A;  4IDY A;  4S01 A;  1WY2 A;  2ZSG A;  4S2T P;  5CDL A;  2GG0 A;  1YW8 A;  2GG8 A;  2G6P A;  1QXY A;  4IKU A;  2GGC A;  1KP0 A;  2GU6 A;  2P9A A;  2OAZ A;  3IU8 A;  4ZWP A;  1WN1 A;  2EVM A;  2P99 A;  3IU9 A;  2BWU A;  4U71 A;  3PKD A;  4RZY A;  1JAW A;  2EVC A;  4R60 A;  1QXW A;  2BHA A;  1A16 A;  2GU7 A;  3FMR A;  2IW2 A;  2P98 A;  1XGS A;  4FUK A;  3S6B A;  1M35 A;  1YW7 A;  1WL9 A;  2NQ7 A;  5CNX A;  4U6Z A;  2GTX A;  5FCH A;  1R5G A;  3BIQ A;  4HXX A;  4FLK A;  3MR1 A;  2DFI A;  2BWT A;  3PKB A;  3PKC A;  1C23 A;  5FCF A;  2ADU A;  5D6E A;  5JI6 A;  2GZ5 A;  2GG5 A;  5JHU A;  2HOW A;  2MAT A;  2GG7 A;  2Q92 A;  4IU6 A;  3PKA A;  1O0X A;  5CDE A;  2GG9 A;  1XNZ A;  4FO8 A;  1WBQ A;  4OOK A;  4U1B A;  2BHC A;  2EA4 A;  4PV4 A;  4S00 A;  4MAT A;  1C21 A;  3CTZ A;  4IEC A;  4KM3 A;  2Q95 A;  4FO7 A;  4U70 A;  3BIT A;  4A6W A;  4ZNG A;  3IU7 A;  4A6V A;  4ZWU A;  1YJ3 A;  2B3K A;  2V3Z A;  4RZZ A;  4B28 A;  2EA2 A;  2V3Y A;  2BB7 A;  3ROR A;  1B6A A;  3MX6 A;  4U6J A;  1YVM A;  2GG2 A;  1C24 A;  2BWW A;  4U69 A;  4FLL A;  2NQ6 A;  3L24 A;  5CDV A;  3IG4 A;  5CLS A;  4JUQ A;  1WL6 A; 
#chains in the Genus database with same CATH topology
 1XGO A;  4IPA A;  3MAT A;  1N51 A;  4Z7M A;  1QXZ A;  3Q6D A;  3RVA A;  2OKN A;  2Q93 A;  1KQ9 A;  2V3X A;  1CHM A;  1QZY A;  2Q96 A;  4RGZ 1;  1XGN A;  2GU4 A;  5E5B A;  1XGM A;  5CIK A;  1BOA A;  3FM3 A;  4FKC A;  4FLI A;  4FLJ A;  4QR8 A;  4PNC A;  2BH3 A;  1R5H A;  1C27 A;  2GA2 A;  5CE6 A;  2B3L A;  2GU5 A;  2BWX A;  4EGE A;  1PV9 A;  2Q8K A;  2B3H A;  1WKM A;  4U6W A;  2BN7 A;  3FMQ A;  3TB5 A;  1Y1N A;  4U76 A;  2BHD A;  2BWY A;  1YW9 A;  1C22 A;  1W7V A;  4U6E A;  3D27 A;  2GGB A;  1W2M A;  3CB6 A;  1KQ0 A;  4IKR A;  3BIP A;  3TAV A;  4IKS A;  4ZWO A;  1BN5 A;  1MAT A;  2BWS A;  5D6F A;  3PKE A;  2BHB A;  4S2R P;  5JFR A;  2Q94 A;  4IF7 A;  2EVO A;  1B59 A;  4U75 A;  4U6C A;  2V6C A;  3L7G A;  3CB5 A;  4IKT A;  2BWV A;  1WLR A;  2GG3 A;  4U73 A;  1R58 A;  4IDY A;  4S01 A;  1WY2 A;  2ZSG A;  4S2T P;  5CDL A;  2GG0 A;  1YW8 A;  2GG8 A;  2G6P A;  1QXY A;  4IKU A;  2GGC A;  1KP0 A;  2GU6 A;  2P9A A;  2OAZ A;  3IU8 A;  4ZWP A;  1WN1 A;  2EVM A;  2P99 A;  3IU9 A;  2BWU A;  4U71 A;  3PKD A;  4RZY A;  1JAW A;  2EVC A;  4R60 A;  1QXW A;  2BHA A;  1A16 A;  2GU7 A;  3FMR A;  2IW2 A;  2P98 A;  1XGS A;  4FUK A;  3S6B A;  1M35 A;  1YW7 A;  1WL9 A;  2NQ7 A;  5CNX A;  4U6Z A;  2GTX A;  5FCH A;  1R5G A;  3BIQ A;  4HXX A;  4FLK A;  3MR1 A;  2DFI A;  2BWT A;  3PKB A;  3PKC A;  1C23 A;  5FCF A;  2ADU A;  5D6E A;  5JI6 A;  2GZ5 A;  2GG5 A;  5JHU A;  2HOW A;  2MAT A;  2GG7 A;  2Q92 A;  4IU6 A;  3PKA A;  1O0X A;  5CDE A;  2GG9 A;  1XNZ A;  4FO8 A;  1WBQ A;  4OOK A;  4U1B A;  2BHC A;  2EA4 A;  4PV4 A;  4S00 A;  4MAT A;  1C21 A;  3CTZ A;  4IEC A;  4KM3 A;  2Q95 A;  4FO7 A;  4U70 A;  3BIT A;  4A6W A;  4ZNG A;  3IU7 A;  4A6V A;  4ZWU A;  1YJ3 A;  2B3K A;  2V3Z A;  4RZZ A;  4B28 A;  2EA2 A;  2V3Y A;  2BB7 A;  3ROR A;  1B6A A;  3MX6 A;  4U6J A;  1YVM A;  2GG2 A;  1C24 A;  2BWW A;  4U69 A;  4FLL A;  2NQ6 A;  3L24 A;  5CDV A;  3IG4 A;  5CLS A;  4JUQ A;  1WL6 A; 
#chains in the Genus database with same CATH homology
 1XGO A;  4IPA A;  3MAT A;  1N51 A;  4Z7M A;  1QXZ A;  3Q6D A;  3RVA A;  2OKN A;  2Q93 A;  1KQ9 A;  2V3X A;  1CHM A;  1QZY A;  2Q96 A;  4RGZ 1;  1XGN A;  2GU4 A;  5E5B A;  1XGM A;  5CIK A;  1BOA A;  3FM3 A;  4FKC A;  4FLI A;  4FLJ A;  4QR8 A;  4PNC A;  2BH3 A;  1R5H A;  1C27 A;  2GA2 A;  5CE6 A;  2B3L A;  2GU5 A;  2BWX A;  4EGE A;  1PV9 A;  2Q8K A;  2B3H A;  1WKM A;  4U6W A;  2BN7 A;  3FMQ A;  3TB5 A;  1Y1N A;  4U76 A;  2BHD A;  2BWY A;  1YW9 A;  1C22 A;  1W7V A;  4U6E A;  3D27 A;  2GGB A;  1W2M A;  3CB6 A;  1KQ0 A;  4IKR A;  3BIP A;  3TAV A;  4IKS A;  4ZWO A;  1BN5 A;  1MAT A;  2BWS A;  5D6F A;  3PKE A;  2BHB A;  4S2R P;  5JFR A;  2Q94 A;  4IF7 A;  2EVO A;  1B59 A;  4U75 A;  4U6C A;  2V6C A;  3L7G A;  3CB5 A;  4IKT A;  2BWV A;  1WLR A;  2GG3 A;  4U73 A;  1R58 A;  4IDY A;  4S01 A;  1WY2 A;  2ZSG A;  4S2T P;  5CDL A;  2GG0 A;  1YW8 A;  2GG8 A;  2G6P A;  1QXY A;  4IKU A;  2GGC A;  1KP0 A;  2GU6 A;  2P9A A;  2OAZ A;  3IU8 A;  4ZWP A;  1WN1 A;  2EVM A;  2P99 A;  3IU9 A;  2BWU A;  4U71 A;  3PKD A;  4RZY A;  1JAW A;  2EVC A;  4R60 A;  1QXW A;  2BHA A;  1A16 A;  2GU7 A;  3FMR A;  2IW2 A;  2P98 A;  1XGS A;  4FUK A;  3S6B A;  1M35 A;  1YW7 A;  1WL9 A;  2NQ7 A;  5CNX A;  4U6Z A;  2GTX A;  5FCH A;  1R5G A;  3BIQ A;  4HXX A;  4FLK A;  3MR1 A;  2DFI A;  2BWT A;  3PKB A;  3PKC A;  1C23 A;  5FCF A;  2ADU A;  5D6E A;  5JI6 A;  2GZ5 A;  2GG5 A;  5JHU A;  2HOW A;  2MAT A;  2GG7 A;  2Q92 A;  4IU6 A;  3PKA A;  1O0X A;  5CDE A;  2GG9 A;  1XNZ A;  4FO8 A;  1WBQ A;  4OOK A;  4U1B A;  2BHC A;  2EA4 A;  4PV4 A;  4S00 A;  4MAT A;  1C21 A;  3CTZ A;  4IEC A;  4KM3 A;  2Q95 A;  4FO7 A;  4U70 A;  3BIT A;  4A6W A;  4ZNG A;  3IU7 A;  4A6V A;  4ZWU A;  1YJ3 A;  2B3K A;  2V3Z A;  4RZZ A;  4B28 A;  2EA2 A;  2V3Y A;  2BB7 A;  3ROR A;  1B6A A;  3MX6 A;  4U6J A;  1YVM A;  2GG2 A;  1C24 A;  2BWW A;  4U69 A;  4FLL A;  2NQ6 A;  3L24 A;  5CDV A;  3IG4 A;  5CLS A;  4JUQ A;  1WL6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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