3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule keywords Methionine aminopeptidase
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
2EVOA 5JFRA 3MR1A 2NQ7A 2ZSGA 1WL6A 1PV9A 3RVAA 3PKAA 4U6EA 5JI6A 1R58A 4EGEA 1A16A 2BHBA 4U6JA 2BB7A 3CB5A 1WBQA 1WN1A 2Q93A 1C24A 3BIQA 1YVMA 4IDYA 2V3XA 3CB6A 2DFIA 4IF7A 5D6EA 4S2TP 4RGZ1 1JAWA 4IU6A 3PKBA 4U75A 1QZYA 4ZWOA 1KQ9A 2GGCA 2BHDA 5CLSA 3BIPA 2BHCA 2BWVA 2GU6A 5CDEA 4U6WA 3S6BA 2GG8A 5CNXA 1B6AA 1C23A 2P99A 2GG5A 2ADUA 3BITA 1XGOA 2BH3A 2NQ6A 2GG2A 4PNCA 2BWWA 4IECA 5FCFA 3PKEA 4KM3A 4PV4A 2GG7A 2B3KA 1WY2A 4FKCA 3IU8A 1YW9A 1W2MA 4QR8A 1WKMA 4A6WA 1BOAA 4ZWUA 2GA2A 2BWUA 1C27A 2OAZA 3RORA 1C22A 4HXXA 4FLJA 4FLLA 4FO8A 1XNZA 2Q92A 3IU7A 1YJ3A 2BWXA 1XGNA 2BWSA 3FMQA 1M35A 2GU7A 2GU5A 4U1BA 4FUKA 4ZWPA 1XGMA 1XGSA 3D27A 4RZZA 4U76A 4U71A 4U6ZA 3CTZA 4B28A 1BN5A 1YW8A 3FM3A 2GG0A 4ZNGA 4A6VA 4U6CA 2BWYA 3Q6DA 2EA2A 3MX6A 5CIKA 1QXYA 1Y1NA 3IG4A 4JUQA 1R5HA 3TAVA 2G6PA 4R60A 5E5BA 5FCHA 2V3YA 1R5GA 4S01A 4S00A 1B59A 1C21A 2Q94A 3L24A 4IKUA 1QXZA 2B3HA 1QXWA 1WL9A 2GG3A 4IKSA 1MATA 1W7VA 2GU4A 1WLRA 4IKRA 2GG9A 5CDLA 4U69A 2BWTA 1O0XA 4S2RP 2P9AA 2OKNA 5CDVA 4MATA 2B3LA 2GZ5A 2V6CA 5D6FA 2IW2A 2Q95A 4OOKA 3IU9A 2MATA 4FO7A 4FLKA 3L7GA 4U73A 4U70A 2EVMA 3PKCA 2Q96A 2EVCA 2EA4A 2BN7A 2HOWA 4RZYA 1KQ0A 1CHMA 3PKDA 4FLIA 4Z7MA 3FMRA 1YW7A 2GGBA 4IKTA 1KP0A 5JHUA 3MATA 2BHAA 5CE6A 2V3ZA 4IPAA 1N51A 3TB5A 2GTXA 2Q8KA 2P98A
chains in the Genus database with same CATH superfamily
2EVOA 5JFRA 3MR1A 2NQ7A 2ZSGA 1WL6A 1PV9A 3RVAA 3PKAA 4U6EA 5JI6A 1R58A 4EGEA 1A16A 2BHBA 4U6JA 2BB7A 3CB5A 1WBQA 1WN1A 2Q93A 1C24A 3BIQA 1YVMA 4IDYA 2V3XA 3CB6A 2DFIA 4IF7A 5D6EA 4S2TP 4RGZ1 1JAWA 4IU6A 3PKBA 4U75A 1QZYA 4ZWOA 1KQ9A 2GGCA 2BHDA 5CLSA 3BIPA 2BHCA 2BWVA 2GU6A 5CDEA 4U6WA 3S6BA 2GG8A 5CNXA 1B6AA 1C23A 2P99A 2GG5A 2ADUA 3BITA 1XGOA 2BH3A 2NQ6A 2GG2A 4PNCA 2BWWA 4IECA 5FCFA 3PKEA 4KM3A 4PV4A 2GG7A 2B3KA 1WY2A 4FKCA 3IU8A 1YW9A 1W2MA 4QR8A 1WKMA 4A6WA 1BOAA 4ZWUA 2GA2A 2BWUA 1C27A 2OAZA 3RORA 1C22A 4HXXA 4FLJA 4FLLA 4FO8A 1XNZA 2Q92A 3IU7A 1YJ3A 2BWXA 1XGNA 2BWSA 3FMQA 1M35A 2GU7A 2GU5A 4U1BA 4FUKA 4ZWPA 1XGMA 1XGSA 3D27A 4RZZA 4U76A 4U71A 4U6ZA 3CTZA 4B28A 1BN5A 1YW8A 3FM3A 2GG0A 4ZNGA 4A6VA 4U6CA 2BWYA 3Q6DA 2EA2A 3MX6A 5CIKA 1QXYA 1Y1NA 3IG4A 4JUQA 1R5HA 3TAVA 2G6PA 4R60A 5E5BA 5FCHA 2V3YA 1R5GA 4S01A 4S00A 1B59A 1C21A 2Q94A 3L24A 4IKUA 1QXZA 2B3HA 1QXWA 1WL9A 2GG3A 4IKSA 1MATA 1W7VA 2GU4A 1WLRA 4IKRA 2GG9A 5CDLA 4U69A 2BWTA 1O0XA 4S2RP 2P9AA 2OKNA 5CDVA 4MATA 2B3LA 2GZ5A 2V6CA 5D6FA 2IW2A 2Q95A 4OOKA 3IU9A 2MATA 4FO7A 4FLKA 3L7GA 4U73A 4U70A 2EVMA 3PKCA 2Q96A 2EVCA 2EA4A 2BN7A 2HOWA 4RZYA 1KQ0A 1CHMA 3PKDA 4FLIA 4Z7MA 3FMRA 1YW7A 2GGBA 4IKTA 1KP0A 5JHUA 3MATA 2BHAA 5CE6A 2V3ZA 4IPAA 1N51A 3TB5A 2GTXA 2Q8KA 2P98A
chains in the Genus database with same CATH topology
2EVOA 5JFRA 3MR1A 2NQ7A 2ZSGA 1WL6A 1PV9A 3RVAA 3PKAA 4U6EA 5JI6A 1R58A 4EGEA 1A16A 2BHBA 4U6JA 2BB7A 3CB5A 1WBQA 1WN1A 2Q93A 1C24A 3BIQA 1YVMA 4IDYA 2V3XA 3CB6A 2DFIA 4IF7A 5D6EA 4S2TP 4RGZ1 1JAWA 4IU6A 3PKBA 4U75A 1QZYA 4ZWOA 1KQ9A 2GGCA 2BHDA 5CLSA 3BIPA 2BHCA 2BWVA 2GU6A 5CDEA 4U6WA 3S6BA 2GG8A 5CNXA 1B6AA 1C23A 2P99A 2GG5A 2ADUA 3BITA 1XGOA 2BH3A 2NQ6A 2GG2A 4PNCA 2BWWA 4IECA 5FCFA 3PKEA 4KM3A 4PV4A 2GG7A 2B3KA 1WY2A 4FKCA 3IU8A 1YW9A 1W2MA 4QR8A 1WKMA 4A6WA 1BOAA 4ZWUA 2GA2A 2BWUA 1C27A 2OAZA 3RORA 1C22A 4HXXA 4FLJA 4FLLA 4FO8A 1XNZA 2Q92A 3IU7A 1YJ3A 2BWXA 1XGNA 2BWSA 3FMQA 1M35A 2GU7A 2GU5A 4U1BA 4FUKA 4ZWPA 1XGMA 1XGSA 3D27A 4RZZA 4U76A 4U71A 4U6ZA 3CTZA 4B28A 1BN5A 1YW8A 3FM3A 2GG0A 4ZNGA 4A6VA 4U6CA 2BWYA 3Q6DA 2EA2A 3MX6A 5CIKA 1QXYA 1Y1NA 3IG4A 4JUQA 1R5HA 3TAVA 2G6PA 4R60A 5E5BA 5FCHA 2V3YA 1R5GA 4S01A 4S00A 1B59A 1C21A 2Q94A 3L24A 4IKUA 1QXZA 2B3HA 1QXWA 1WL9A 2GG3A 4IKSA 1MATA 1W7VA 2GU4A 1WLRA 4IKRA 2GG9A 5CDLA 4U69A 2BWTA 1O0XA 4S2RP 2P9AA 2OKNA 5CDVA 4MATA 2B3LA 2GZ5A 2V6CA 5D6FA 2IW2A 2Q95A 4OOKA 3IU9A 2MATA 4FO7A 4FLKA 3L7GA 4U73A 4U70A 2EVMA 3PKCA 2Q96A 2EVCA 2EA4A 2BN7A 2HOWA 4RZYA 1KQ0A 1CHMA 3PKDA 4FLIA 4Z7MA 3FMRA 1YW7A 2GGBA 4IKTA 1KP0A 5JHUA 3MATA 2BHAA 5CE6A 2V3ZA 4IPAA 1N51A 3TB5A 2GTXA 2Q8KA 2P98A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2EVO A;  5JFR A;  3MR1 A;  2NQ7 A;  2ZSG A;  1WL6 A;  1PV9 A;  3RVA A;  3PKA A;  4U6E A;  5JI6 A;  1R58 A;  4EGE A;  1A16 A;  2BHB A;  4U6J A;  2BB7 A;  3CB5 A;  1WBQ A;  1WN1 A;  2Q93 A;  1C24 A;  3BIQ A;  1YVM A;  4IDY A;  2V3X A;  3CB6 A;  2DFI A;  4IF7 A;  5D6E A;  4S2T P;  4RGZ 1;  1JAW A;  4IU6 A;  3PKB A;  4U75 A;  1QZY A;  4ZWO A;  1KQ9 A;  2GGC A;  2BHD A;  5CLS A;  3BIP A;  2BHC A;  2BWV A;  2GU6 A;  5CDE A;  4U6W A;  3S6B A;  2GG8 A;  5CNX A;  1B6A A;  1C23 A;  2P99 A;  2GG5 A;  2ADU A;  3BIT A;  1XGO A;  2BH3 A;  2NQ6 A;  2GG2 A;  4PNC A;  2BWW A;  4IEC A;  5FCF A;  3PKE A;  4KM3 A;  4PV4 A;  2GG7 A;  2B3K A;  1WY2 A;  4FKC A;  3IU8 A;  1YW9 A;  1W2M A;  4QR8 A;  1WKM A;  4A6W A;  1BOA A;  4ZWU A;  2GA2 A;  2BWU A;  1C27 A;  2OAZ A;  3ROR A;  1C22 A;  4HXX A;  4FLJ A;  4FLL A;  4FO8 A;  1XNZ A;  2Q92 A;  3IU7 A;  1YJ3 A;  2BWX A;  1XGN A;  2BWS A;  3FMQ A;  1M35 A;  2GU7 A;  2GU5 A;  4U1B A;  4FUK A;  4ZWP A;  1XGM A;  1XGS A;  3D27 A;  4RZZ A;  4U76 A;  4U71 A;  4U6Z A;  3CTZ A;  4B28 A;  1BN5 A;  1YW8 A;  3FM3 A;  2GG0 A;  4ZNG A;  4A6V A;  4U6C A;  2BWY A;  3Q6D A;  2EA2 A;  3MX6 A;  5CIK A;  1QXY A;  1Y1N A;  3IG4 A;  4JUQ A;  1R5H A;  3TAV A;  2G6P A;  4R60 A;  5E5B A;  5FCH A;  2V3Y A;  1R5G A;  4S01 A;  4S00 A;  1B59 A;  1C21 A;  2Q94 A;  3L24 A;  4IKU A;  1QXZ A;  2B3H A;  1QXW A;  1WL9 A;  2GG3 A;  4IKS A;  1MAT A;  1W7V A;  2GU4 A;  1WLR A;  4IKR A;  2GG9 A;  5CDL A;  4U69 A;  2BWT A;  1O0X A;  4S2R P;  2P9A A;  2OKN A;  5CDV A;  4MAT A;  2B3L A;  2GZ5 A;  2V6C A;  5D6F A;  2IW2 A;  2Q95 A;  4OOK A;  3IU9 A;  2MAT A;  4FO7 A;  4FLK A;  3L7G A;  4U73 A;  4U70 A;  2EVM A;  3PKC A;  2Q96 A;  2EVC A;  2EA4 A;  2BN7 A;  2HOW A;  4RZY A;  1KQ0 A;  1CHM A;  3PKD A;  4FLI A;  4Z7M A;  3FMR A;  1YW7 A;  2GGB A;  4IKT A;  1KP0 A;  5JHU A;  3MAT A;  2BHA A;  5CE6 A;  2V3Z A;  4IPA A;  1N51 A;  3TB5 A;  2GTX A;  2Q8K A;  2P98 A; 
#chains in the Genus database with same CATH topology
 2EVO A;  5JFR A;  3MR1 A;  2NQ7 A;  2ZSG A;  1WL6 A;  1PV9 A;  3RVA A;  3PKA A;  4U6E A;  5JI6 A;  1R58 A;  4EGE A;  1A16 A;  2BHB A;  4U6J A;  2BB7 A;  3CB5 A;  1WBQ A;  1WN1 A;  2Q93 A;  1C24 A;  3BIQ A;  1YVM A;  4IDY A;  2V3X A;  3CB6 A;  2DFI A;  4IF7 A;  5D6E A;  4S2T P;  4RGZ 1;  1JAW A;  4IU6 A;  3PKB A;  4U75 A;  1QZY A;  4ZWO A;  1KQ9 A;  2GGC A;  2BHD A;  5CLS A;  3BIP A;  2BHC A;  2BWV A;  2GU6 A;  5CDE A;  4U6W A;  3S6B A;  2GG8 A;  5CNX A;  1B6A A;  1C23 A;  2P99 A;  2GG5 A;  2ADU A;  3BIT A;  1XGO A;  2BH3 A;  2NQ6 A;  2GG2 A;  4PNC A;  2BWW A;  4IEC A;  5FCF A;  3PKE A;  4KM3 A;  4PV4 A;  2GG7 A;  2B3K A;  1WY2 A;  4FKC A;  3IU8 A;  1YW9 A;  1W2M A;  4QR8 A;  1WKM A;  4A6W A;  1BOA A;  4ZWU A;  2GA2 A;  2BWU A;  1C27 A;  2OAZ A;  3ROR A;  1C22 A;  4HXX A;  4FLJ A;  4FLL A;  4FO8 A;  1XNZ A;  2Q92 A;  3IU7 A;  1YJ3 A;  2BWX A;  1XGN A;  2BWS A;  3FMQ A;  1M35 A;  2GU7 A;  2GU5 A;  4U1B A;  4FUK A;  4ZWP A;  1XGM A;  1XGS A;  3D27 A;  4RZZ A;  4U76 A;  4U71 A;  4U6Z A;  3CTZ A;  4B28 A;  1BN5 A;  1YW8 A;  3FM3 A;  2GG0 A;  4ZNG A;  4A6V A;  4U6C A;  2BWY A;  3Q6D A;  2EA2 A;  3MX6 A;  5CIK A;  1QXY A;  1Y1N A;  3IG4 A;  4JUQ A;  1R5H A;  3TAV A;  2G6P A;  4R60 A;  5E5B A;  5FCH A;  2V3Y A;  1R5G A;  4S01 A;  4S00 A;  1B59 A;  1C21 A;  2Q94 A;  3L24 A;  4IKU A;  1QXZ A;  2B3H A;  1QXW A;  1WL9 A;  2GG3 A;  4IKS A;  1MAT A;  1W7V A;  2GU4 A;  1WLR A;  4IKR A;  2GG9 A;  5CDL A;  4U69 A;  2BWT A;  1O0X A;  4S2R P;  2P9A A;  2OKN A;  5CDV A;  4MAT A;  2B3L A;  2GZ5 A;  2V6C A;  5D6F A;  2IW2 A;  2Q95 A;  4OOK A;  3IU9 A;  2MAT A;  4FO7 A;  4FLK A;  3L7G A;  4U73 A;  4U70 A;  2EVM A;  3PKC A;  2Q96 A;  2EVC A;  2EA4 A;  2BN7 A;  2HOW A;  4RZY A;  1KQ0 A;  1CHM A;  3PKD A;  4FLI A;  4Z7M A;  3FMR A;  1YW7 A;  2GGB A;  4IKT A;  1KP0 A;  5JHU A;  3MAT A;  2BHA A;  5CE6 A;  2V3Z A;  4IPA A;  1N51 A;  3TB5 A;  2GTX A;  2Q8K A;  2P98 A; 
#chains in the Genus database with same CATH homology
 2EVO A;  5JFR A;  3MR1 A;  2NQ7 A;  2ZSG A;  1WL6 A;  1PV9 A;  3RVA A;  3PKA A;  4U6E A;  5JI6 A;  1R58 A;  4EGE A;  1A16 A;  2BHB A;  4U6J A;  2BB7 A;  3CB5 A;  1WBQ A;  1WN1 A;  2Q93 A;  1C24 A;  3BIQ A;  1YVM A;  4IDY A;  2V3X A;  3CB6 A;  2DFI A;  4IF7 A;  5D6E A;  4S2T P;  4RGZ 1;  1JAW A;  4IU6 A;  3PKB A;  4U75 A;  1QZY A;  4ZWO A;  1KQ9 A;  2GGC A;  2BHD A;  5CLS A;  3BIP A;  2BHC A;  2BWV A;  2GU6 A;  5CDE A;  4U6W A;  3S6B A;  2GG8 A;  5CNX A;  1B6A A;  1C23 A;  2P99 A;  2GG5 A;  2ADU A;  3BIT A;  1XGO A;  2BH3 A;  2NQ6 A;  2GG2 A;  4PNC A;  2BWW A;  4IEC A;  5FCF A;  3PKE A;  4KM3 A;  4PV4 A;  2GG7 A;  2B3K A;  1WY2 A;  4FKC A;  3IU8 A;  1YW9 A;  1W2M A;  4QR8 A;  1WKM A;  4A6W A;  1BOA A;  4ZWU A;  2GA2 A;  2BWU A;  1C27 A;  2OAZ A;  3ROR A;  1C22 A;  4HXX A;  4FLJ A;  4FLL A;  4FO8 A;  1XNZ A;  2Q92 A;  3IU7 A;  1YJ3 A;  2BWX A;  1XGN A;  2BWS A;  3FMQ A;  1M35 A;  2GU7 A;  2GU5 A;  4U1B A;  4FUK A;  4ZWP A;  1XGM A;  1XGS A;  3D27 A;  4RZZ A;  4U76 A;  4U71 A;  4U6Z A;  3CTZ A;  4B28 A;  1BN5 A;  1YW8 A;  3FM3 A;  2GG0 A;  4ZNG A;  4A6V A;  4U6C A;  2BWY A;  3Q6D A;  2EA2 A;  3MX6 A;  5CIK A;  1QXY A;  1Y1N A;  3IG4 A;  4JUQ A;  1R5H A;  3TAV A;  2G6P A;  4R60 A;  5E5B A;  5FCH A;  2V3Y A;  1R5G A;  4S01 A;  4S00 A;  1B59 A;  1C21 A;  2Q94 A;  3L24 A;  4IKU A;  1QXZ A;  2B3H A;  1QXW A;  1WL9 A;  2GG3 A;  4IKS A;  1MAT A;  1W7V A;  2GU4 A;  1WLR A;  4IKR A;  2GG9 A;  5CDL A;  4U69 A;  2BWT A;  1O0X A;  4S2R P;  2P9A A;  2OKN A;  5CDV A;  4MAT A;  2B3L A;  2GZ5 A;  2V6C A;  5D6F A;  2IW2 A;  2Q95 A;  4OOK A;  3IU9 A;  2MAT A;  4FO7 A;  4FLK A;  3L7G A;  4U73 A;  4U70 A;  2EVM A;  3PKC A;  2Q96 A;  2EVC A;  2EA4 A;  2BN7 A;  2HOW A;  4RZY A;  1KQ0 A;  1CHM A;  3PKD A;  4FLI A;  4Z7M A;  3FMR A;  1YW7 A;  2GGB A;  4IKT A;  1KP0 A;  5JHU A;  3MAT A;  2BHA A;  5CE6 A;  2V3Z A;  4IPA A;  1N51 A;  3TB5 A;  2GTX A;  2Q8K A;  2P98 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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