3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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molecule tags Hydrolase
source organism Mycobacterium tuberculosis
publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
3BITA 5CLSA 4IKUA 1XGNA 2G6PA 2HOWA 2ZSGA 1WBQA 2GG9A 2V3YA 2NQ7A 3IU7A 4RZYA 1C24A 2GGCA 1W2MA 5FCFA 1BOAA 3BIQA 2Q8KA 2GU4A 4U6JA 2EVCA 1R58A 3IU8A 4PNCA 2V3ZA 4U70A 4FLJA 4IF7A 1B59A 3FMQA 3MR1A 2OAZA 4MATA 2BHDA 1XGOA 3CB6A 1R5GA 3PKCA 2GU6A 2BHAA 4S2RP 5D6EA 1QXWA 1O0XA 2P9AA 2BHBA 3PKEA 2Q94A 3CB5A 4IECA 5E5BA 3BIPA 2GG2A 2GG7A 5JI6A 1KQ9A 1W7VA 1N51A 4FO7A 5CDLA 2Q95A 1WLRA 1CHMA 1B6AA 2BWYA 2MATA 3IG4A 2BN7A 3L7GA 3MATA 4IKTA 4A6WA 1XGSA 4ZNGA 1Y1NA 4FLKA 1C22A 1C21A 1PV9A 4ZWPA 3PKBA 1WKMA 2GG3A 2BH3A 2IW2A 2DFIA 4U75A 1YW9A 2B3LA 4S01A 2GG5A 1JAWA 1KQ0A 3S6BA 2BHCA 3TB5A 2V3XA 2BWSA 2GG8A 4IU6A 4U6CA 3D27A 2Q96A 4FLLA 4Z7MA 2EA4A 4FUKA 4U6ZA 2GZ5A 2NQ6A 1MATA 1R5HA 4PV4A 5JFRA 2B3KA 4U6EA 5FCHA 4ZWOA 2BWWA 3PKAA 4IKSA 3CTZA 1YW8A 1YVMA 2BWVA 4HXXA 2BWTA 5CIKA 2Q92A 2ADUA 5CDEA 2Q93A 5CNXA 1QZYA 3IU9A 1WL9A 4B28A 4QR8A 4OOKA 2GG0A 2V6CA 2P98A 4RZZA 4U1BA 1YJ3A 3TAVA 3MX6A 2EVMA 4IKRA 4EGEA 2BB7A 3FMRA 4S00A 4A6VA 1XGMA 1C23A 2BWUA 4IPAA 1WL6A 3Q6DA 4U76A 1KP0A 1WY2A 3L24A 4JUQA 4FO8A 1XNZA 4KM3A 1YW7A 4FKCA 4U6WA 2BWXA 4U71A 5CE6A 4U69A 4R60A 4U73A 1M35A 2GU7A 4RGZ1 5D6FA 5JHUA 2B3HA 3RORA 1QXYA 2GU5A 4IDYA 3PKDA 4ZWUA 2GA2A 4FLIA 1A16A 1WN1A 2EVOA 5CDVA 3RVAA 2P99A 2OKNA 1BN5A 3FM3A 1C27A 2EA2A 2GGBA 1QXZA 4S2TP 2GTXA
chains in the Genus database with same CATH superfamily
3BITA 5CLSA 4IKUA 1XGNA 2G6PA 2HOWA 2ZSGA 1WBQA 2GG9A 2V3YA 2NQ7A 3IU7A 4RZYA 1C24A 2GGCA 1W2MA 5FCFA 1BOAA 3BIQA 2Q8KA 2GU4A 4U6JA 2EVCA 1R58A 3IU8A 4PNCA 2V3ZA 4U70A 4FLJA 4IF7A 1B59A 3FMQA 3MR1A 2OAZA 4MATA 2BHDA 1XGOA 3CB6A 1R5GA 3PKCA 2GU6A 2BHAA 4S2RP 5D6EA 1QXWA 1O0XA 2P9AA 2BHBA 3PKEA 2Q94A 3CB5A 4IECA 5E5BA 3BIPA 2GG2A 2GG7A 5JI6A 1KQ9A 1W7VA 1N51A 4FO7A 5CDLA 2Q95A 1WLRA 1CHMA 1B6AA 2BWYA 2MATA 3IG4A 2BN7A 3L7GA 3MATA 4IKTA 4A6WA 1XGSA 4ZNGA 1Y1NA 4FLKA 1C22A 1C21A 1PV9A 4ZWPA 3PKBA 1WKMA 2GG3A 2BH3A 2IW2A 2DFIA 4U75A 1YW9A 2B3LA 4S01A 2GG5A 1JAWA 1KQ0A 3S6BA 2BHCA 3TB5A 2V3XA 2BWSA 2GG8A 4IU6A 4U6CA 3D27A 2Q96A 4FLLA 4Z7MA 2EA4A 4FUKA 4U6ZA 2GZ5A 2NQ6A 1MATA 1R5HA 4PV4A 5JFRA 2B3KA 4U6EA 5FCHA 4ZWOA 2BWWA 3PKAA 4IKSA 3CTZA 1YW8A 1YVMA 2BWVA 4HXXA 2BWTA 5CIKA 2Q92A 2ADUA 5CDEA 2Q93A 5CNXA 1QZYA 3IU9A 1WL9A 4B28A 4QR8A 4OOKA 2GG0A 2V6CA 2P98A 4RZZA 4U1BA 1YJ3A 3TAVA 3MX6A 2EVMA 4IKRA 4EGEA 2BB7A 3FMRA 4S00A 4A6VA 1XGMA 1C23A 2BWUA 4IPAA 1WL6A 3Q6DA 4U76A 1KP0A 1WY2A 3L24A 4JUQA 4FO8A 1XNZA 4KM3A 1YW7A 4FKCA 4U6WA 2BWXA 4U71A 5CE6A 4U69A 4R60A 4U73A 1M35A 2GU7A 4RGZ1 5D6FA 5JHUA 2B3HA 3RORA 1QXYA 2GU5A 4IDYA 3PKDA 4ZWUA 2GA2A 4FLIA 1A16A 1WN1A 2EVOA 5CDVA 3RVAA 2P99A 2OKNA 1BN5A 3FM3A 1C27A 2EA2A 2GGBA 1QXZA 4S2TP 2GTXA
chains in the Genus database with same CATH topology
3BITA 5CLSA 4IKUA 1XGNA 2G6PA 2HOWA 2ZSGA 1WBQA 2GG9A 2V3YA 2NQ7A 3IU7A 4RZYA 1C24A 2GGCA 1W2MA 5FCFA 1BOAA 3BIQA 2Q8KA 2GU4A 4U6JA 2EVCA 1R58A 3IU8A 4PNCA 2V3ZA 4U70A 4FLJA 4IF7A 1B59A 3FMQA 3MR1A 2OAZA 4MATA 2BHDA 1XGOA 3CB6A 1R5GA 3PKCA 2GU6A 2BHAA 4S2RP 5D6EA 1QXWA 1O0XA 2P9AA 2BHBA 3PKEA 2Q94A 3CB5A 4IECA 5E5BA 3BIPA 2GG2A 2GG7A 5JI6A 1KQ9A 1W7VA 1N51A 4FO7A 5CDLA 2Q95A 1WLRA 1CHMA 1B6AA 2BWYA 2MATA 3IG4A 2BN7A 3L7GA 3MATA 4IKTA 4A6WA 1XGSA 4ZNGA 1Y1NA 4FLKA 1C22A 1C21A 1PV9A 4ZWPA 3PKBA 1WKMA 2GG3A 2BH3A 2IW2A 2DFIA 4U75A 1YW9A 2B3LA 4S01A 2GG5A 1JAWA 1KQ0A 3S6BA 2BHCA 3TB5A 2V3XA 2BWSA 2GG8A 4IU6A 4U6CA 3D27A 2Q96A 4FLLA 4Z7MA 2EA4A 4FUKA 4U6ZA 2GZ5A 2NQ6A 1MATA 1R5HA 4PV4A 5JFRA 2B3KA 4U6EA 5FCHA 4ZWOA 2BWWA 3PKAA 4IKSA 3CTZA 1YW8A 1YVMA 2BWVA 4HXXA 2BWTA 5CIKA 2Q92A 2ADUA 5CDEA 2Q93A 5CNXA 1QZYA 3IU9A 1WL9A 4B28A 4QR8A 4OOKA 2GG0A 2V6CA 2P98A 4RZZA 4U1BA 1YJ3A 3TAVA 3MX6A 2EVMA 4IKRA 4EGEA 2BB7A 3FMRA 4S00A 4A6VA 1XGMA 1C23A 2BWUA 4IPAA 1WL6A 3Q6DA 4U76A 1KP0A 1WY2A 3L24A 4JUQA 4FO8A 1XNZA 4KM3A 1YW7A 4FKCA 4U6WA 2BWXA 4U71A 5CE6A 4U69A 4R60A 4U73A 1M35A 2GU7A 4RGZ1 5D6FA 5JHUA 2B3HA 3RORA 1QXYA 2GU5A 4IDYA 3PKDA 4ZWUA 2GA2A 4FLIA 1A16A 1WN1A 2EVOA 5CDVA 3RVAA 2P99A 2OKNA 1BN5A 3FM3A 1C27A 2EA2A 2GGBA 1QXZA 4S2TP 2GTXA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3BIT A;  5CLS A;  4IKU A;  1XGN A;  2G6P A;  2HOW A;  2ZSG A;  1WBQ A;  2GG9 A;  2V3Y A;  2NQ7 A;  3IU7 A;  4RZY A;  1C24 A;  2GGC A;  1W2M A;  5FCF A;  1BOA A;  3BIQ A;  2Q8K A;  2GU4 A;  4U6J A;  2EVC A;  1R58 A;  3IU8 A;  4PNC A;  2V3Z A;  4U70 A;  4FLJ A;  4IF7 A;  1B59 A;  3FMQ A;  3MR1 A;  2OAZ A;  4MAT A;  2BHD A;  1XGO A;  3CB6 A;  1R5G A;  3PKC A;  2GU6 A;  2BHA A;  4S2R P;  5D6E A;  1QXW A;  1O0X A;  2P9A A;  2BHB A;  3PKE A;  2Q94 A;  3CB5 A;  4IEC A;  5E5B A;  3BIP A;  2GG2 A;  2GG7 A;  5JI6 A;  1KQ9 A;  1W7V A;  1N51 A;  4FO7 A;  5CDL A;  2Q95 A;  1WLR A;  1CHM A;  1B6A A;  2BWY A;  2MAT A;  3IG4 A;  2BN7 A;  3L7G A;  3MAT A;  4IKT A;  4A6W A;  1XGS A;  4ZNG A;  1Y1N A;  4FLK A;  1C22 A;  1C21 A;  1PV9 A;  4ZWP A;  3PKB A;  1WKM A;  2GG3 A;  2BH3 A;  2IW2 A;  2DFI A;  4U75 A;  1YW9 A;  2B3L A;  4S01 A;  2GG5 A;  1JAW A;  1KQ0 A;  3S6B A;  2BHC A;  3TB5 A;  2V3X A;  2BWS A;  2GG8 A;  4IU6 A;  4U6C A;  3D27 A;  2Q96 A;  4FLL A;  4Z7M A;  2EA4 A;  4FUK A;  4U6Z A;  2GZ5 A;  2NQ6 A;  1MAT A;  1R5H A;  4PV4 A;  5JFR A;  2B3K A;  4U6E A;  5FCH A;  4ZWO A;  2BWW A;  3PKA A;  4IKS A;  3CTZ A;  1YW8 A;  1YVM A;  2BWV A;  4HXX A;  2BWT A;  5CIK A;  2Q92 A;  2ADU A;  5CDE A;  2Q93 A;  5CNX A;  1QZY A;  3IU9 A;  1WL9 A;  4B28 A;  4QR8 A;  4OOK A;  2GG0 A;  2V6C A;  2P98 A;  4RZZ A;  4U1B A;  1YJ3 A;  3TAV A;  3MX6 A;  2EVM A;  4IKR A;  4EGE A;  2BB7 A;  3FMR A;  4S00 A;  4A6V A;  1XGM A;  1C23 A;  2BWU A;  4IPA A;  1WL6 A;  3Q6D A;  4U76 A;  1KP0 A;  1WY2 A;  3L24 A;  4JUQ A;  4FO8 A;  1XNZ A;  4KM3 A;  1YW7 A;  4FKC A;  4U6W A;  2BWX A;  4U71 A;  5CE6 A;  4U69 A;  4R60 A;  4U73 A;  1M35 A;  2GU7 A;  4RGZ 1;  5D6F A;  5JHU A;  2B3H A;  3ROR A;  1QXY A;  2GU5 A;  4IDY A;  3PKD A;  4ZWU A;  2GA2 A;  4FLI A;  1A16 A;  1WN1 A;  2EVO A;  5CDV A;  3RVA A;  2P99 A;  2OKN A;  1BN5 A;  3FM3 A;  1C27 A;  2EA2 A;  2GGB A;  1QXZ A;  4S2T P;  2GTX A; 
#chains in the Genus database with same CATH topology
 3BIT A;  5CLS A;  4IKU A;  1XGN A;  2G6P A;  2HOW A;  2ZSG A;  1WBQ A;  2GG9 A;  2V3Y A;  2NQ7 A;  3IU7 A;  4RZY A;  1C24 A;  2GGC A;  1W2M A;  5FCF A;  1BOA A;  3BIQ A;  2Q8K A;  2GU4 A;  4U6J A;  2EVC A;  1R58 A;  3IU8 A;  4PNC A;  2V3Z A;  4U70 A;  4FLJ A;  4IF7 A;  1B59 A;  3FMQ A;  3MR1 A;  2OAZ A;  4MAT A;  2BHD A;  1XGO A;  3CB6 A;  1R5G A;  3PKC A;  2GU6 A;  2BHA A;  4S2R P;  5D6E A;  1QXW A;  1O0X A;  2P9A A;  2BHB A;  3PKE A;  2Q94 A;  3CB5 A;  4IEC A;  5E5B A;  3BIP A;  2GG2 A;  2GG7 A;  5JI6 A;  1KQ9 A;  1W7V A;  1N51 A;  4FO7 A;  5CDL A;  2Q95 A;  1WLR A;  1CHM A;  1B6A A;  2BWY A;  2MAT A;  3IG4 A;  2BN7 A;  3L7G A;  3MAT A;  4IKT A;  4A6W A;  1XGS A;  4ZNG A;  1Y1N A;  4FLK A;  1C22 A;  1C21 A;  1PV9 A;  4ZWP A;  3PKB A;  1WKM A;  2GG3 A;  2BH3 A;  2IW2 A;  2DFI A;  4U75 A;  1YW9 A;  2B3L A;  4S01 A;  2GG5 A;  1JAW A;  1KQ0 A;  3S6B A;  2BHC A;  3TB5 A;  2V3X A;  2BWS A;  2GG8 A;  4IU6 A;  4U6C A;  3D27 A;  2Q96 A;  4FLL A;  4Z7M A;  2EA4 A;  4FUK A;  4U6Z A;  2GZ5 A;  2NQ6 A;  1MAT A;  1R5H A;  4PV4 A;  5JFR A;  2B3K A;  4U6E A;  5FCH A;  4ZWO A;  2BWW A;  3PKA A;  4IKS A;  3CTZ A;  1YW8 A;  1YVM A;  2BWV A;  4HXX A;  2BWT A;  5CIK A;  2Q92 A;  2ADU A;  5CDE A;  2Q93 A;  5CNX A;  1QZY A;  3IU9 A;  1WL9 A;  4B28 A;  4QR8 A;  4OOK A;  2GG0 A;  2V6C A;  2P98 A;  4RZZ A;  4U1B A;  1YJ3 A;  3TAV A;  3MX6 A;  2EVM A;  4IKR A;  4EGE A;  2BB7 A;  3FMR A;  4S00 A;  4A6V A;  1XGM A;  1C23 A;  2BWU A;  4IPA A;  1WL6 A;  3Q6D A;  4U76 A;  1KP0 A;  1WY2 A;  3L24 A;  4JUQ A;  4FO8 A;  1XNZ A;  4KM3 A;  1YW7 A;  4FKC A;  4U6W A;  2BWX A;  4U71 A;  5CE6 A;  4U69 A;  4R60 A;  4U73 A;  1M35 A;  2GU7 A;  4RGZ 1;  5D6F A;  5JHU A;  2B3H A;  3ROR A;  1QXY A;  2GU5 A;  4IDY A;  3PKD A;  4ZWU A;  2GA2 A;  4FLI A;  1A16 A;  1WN1 A;  2EVO A;  5CDV A;  3RVA A;  2P99 A;  2OKN A;  1BN5 A;  3FM3 A;  1C27 A;  2EA2 A;  2GGB A;  1QXZ A;  4S2T P;  2GTX A; 
#chains in the Genus database with same CATH homology
 3BIT A;  5CLS A;  4IKU A;  1XGN A;  2G6P A;  2HOW A;  2ZSG A;  1WBQ A;  2GG9 A;  2V3Y A;  2NQ7 A;  3IU7 A;  4RZY A;  1C24 A;  2GGC A;  1W2M A;  5FCF A;  1BOA A;  3BIQ A;  2Q8K A;  2GU4 A;  4U6J A;  2EVC A;  1R58 A;  3IU8 A;  4PNC A;  2V3Z A;  4U70 A;  4FLJ A;  4IF7 A;  1B59 A;  3FMQ A;  3MR1 A;  2OAZ A;  4MAT A;  2BHD A;  1XGO A;  3CB6 A;  1R5G A;  3PKC A;  2GU6 A;  2BHA A;  4S2R P;  5D6E A;  1QXW A;  1O0X A;  2P9A A;  2BHB A;  3PKE A;  2Q94 A;  3CB5 A;  4IEC A;  5E5B A;  3BIP A;  2GG2 A;  2GG7 A;  5JI6 A;  1KQ9 A;  1W7V A;  1N51 A;  4FO7 A;  5CDL A;  2Q95 A;  1WLR A;  1CHM A;  1B6A A;  2BWY A;  2MAT A;  3IG4 A;  2BN7 A;  3L7G A;  3MAT A;  4IKT A;  4A6W A;  1XGS A;  4ZNG A;  1Y1N A;  4FLK A;  1C22 A;  1C21 A;  1PV9 A;  4ZWP A;  3PKB A;  1WKM A;  2GG3 A;  2BH3 A;  2IW2 A;  2DFI A;  4U75 A;  1YW9 A;  2B3L A;  4S01 A;  2GG5 A;  1JAW A;  1KQ0 A;  3S6B A;  2BHC A;  3TB5 A;  2V3X A;  2BWS A;  2GG8 A;  4IU6 A;  4U6C A;  3D27 A;  2Q96 A;  4FLL A;  4Z7M A;  2EA4 A;  4FUK A;  4U6Z A;  2GZ5 A;  2NQ6 A;  1MAT A;  1R5H A;  4PV4 A;  5JFR A;  2B3K A;  4U6E A;  5FCH A;  4ZWO A;  2BWW A;  3PKA A;  4IKS A;  3CTZ A;  1YW8 A;  1YVM A;  2BWV A;  4HXX A;  2BWT A;  5CIK A;  2Q92 A;  2ADU A;  5CDE A;  2Q93 A;  5CNX A;  1QZY A;  3IU9 A;  1WL9 A;  4B28 A;  4QR8 A;  4OOK A;  2GG0 A;  2V6C A;  2P98 A;  4RZZ A;  4U1B A;  1YJ3 A;  3TAV A;  3MX6 A;  2EVM A;  4IKR A;  4EGE A;  2BB7 A;  3FMR A;  4S00 A;  4A6V A;  1XGM A;  1C23 A;  2BWU A;  4IPA A;  1WL6 A;  3Q6D A;  4U76 A;  1KP0 A;  1WY2 A;  3L24 A;  4JUQ A;  4FO8 A;  1XNZ A;  4KM3 A;  1YW7 A;  4FKC A;  4U6W A;  2BWX A;  4U71 A;  5CE6 A;  4U69 A;  4R60 A;  4U73 A;  1M35 A;  2GU7 A;  4RGZ 1;  5D6F A;  5JHU A;  2B3H A;  3ROR A;  1QXY A;  2GU5 A;  4IDY A;  3PKD A;  4ZWU A;  2GA2 A;  4FLI A;  1A16 A;  1WN1 A;  2EVO A;  5CDV A;  3RVA A;  2P99 A;  2OKN A;  1BN5 A;  3FM3 A;  1C27 A;  2EA2 A;  2GGB A;  1QXZ A;  4S2T P;  2GTX A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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