3IU7A

M. tuberculosis methionine aminopeptidase with mn inhibitor a02
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
284
structure length
284
Chain Sequence
PSRTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Catalysis and Inhibition of Mycobacterium tuberculosis Methionine Aminopeptidase
pubmed doi rcsb
source organism Mycobacterium tuberculosis
molecule tags Hydrolase
molecule keywords Methionine aminopeptidase
total genus 86
structure length 284
sequence length 284
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2009-08-30

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 3iu7A01
4PV4A 2BWXA 2GG5A 5D6FA 5CLSA 1QXWA 4IKRA 3S6BA 2GTXA 4A6VA 2GG0A 3MR1A 1XGMA 3TAVA 4U70A 2BB7A 4HXXA 4EGEA 5CIKA 3IU7A 4IPAA 5JHUA 5D6EA 2DFIA 1BN5A 3D27A 2ADUA 2B3KA 2ZSGA 4ZWUA 4A6WA 2P9AA 1XGNA 4U73A 4B28A 3BIPA 4OOKA 2GG9A 4S00A 4U6WA 4PNCA 3IU8A 3CB5A 1R5GA 2NQ7A 1XNZA 1W7VA 2BHDA 1XGOA 1QXYA 2EVCA 4FUKA 4IECA 4IU6A 2EA4A 1WL6A 4IKUA 1C27A 5CDEA 4FO7A 1M35A 2NQ6A 3PKEA 2BN7A 4FO8A 4R60A 2P99A 3L24A 4S2TP 1MATA 3RVAA 2BWSA 1WKMA 1JAWA 1YVMA 2GG8A 2IW2A 2BHCA 3FMRA 3BITA 2GU6A 2G6PA 1WY2A 1B6AA 4ZNGA 2GG3A 3FMQA 4U6JA 2P98A 4U69A 1W2MA 5CDVA 4IKSA 1Y1NA 4FLIA 1C23A 2OAZA 1R58A 3CB6A 3MATA 4QR8A 2V6CA 3PKCA 5CE6A 4RZYA 1WBQA 3Q6DA 2BWWA 2GGBA 2V3YA 1O0XA 2BHAA 2GG2A 2B3LA 3TB5A 1CHMA 4RZZA 4IDYA 1WN1A 4FLKA 1KQ9A 5E5BA 5JI6A 1YW7A 4U76A 1WLRA 3BIQA 2GU7A 4FLJA 2GGCA 2V3XA 1QZYA 3FM3A 2BWVA 2GU5A 5CDLA 1KP0A 3CTZA 2Q8KA 3MX6A 2Q96A 3PKAA 5JFRA 4FKCA 2GZ5A 1A16A 1WL9A 2Q93A 4U6ZA 2Q95A 4JUQA 3PKBA 4ZWPA 4FLLA 4ZWOA 4S2RP 1KQ0A 2BHBA 1C21A 4KM3A 2MATA 2V3ZA 2BWYA 1YW9A 3IU9A 4S01A 4U6EA 1QXZA 1C22A 2GG7A 2BWTA 4RGZ1 4U6CA 5FCHA 4U71A 5FCFA 2EVMA 1XGSA 1C24A 2Q94A 2EA2A 2B3HA 2HOWA 1YW8A 2BH3A 2BWUA 4MATA 4U75A 1BOAA 1R5HA 3L7GA 2Q92A 1PV9A 4IKTA 2EVOA 2GA2A 3PKDA 1B59A 2GU4A 4U1BA 3IG4A 4IF7A 5CNXA 3RORA 1N51A 2OKNA 1YJ3A 4Z7MA
chains in the Genus database with same CATH superfamily
4PV4A 2BWXA 2GG5A 5D6FA 5CLSA 1QXWA 4IKRA 3S6BA 2GTXA 4A6VA 2GG0A 3MR1A 1XGMA 3TAVA 4U70A 2BB7A 4HXXA 4EGEA 5CIKA 3IU7A 4IPAA 5JHUA 5D6EA 2DFIA 1BN5A 3D27A 2ADUA 2B3KA 2ZSGA 4ZWUA 4A6WA 2P9AA 1XGNA 4U73A 4B28A 3BIPA 4OOKA 2GG9A 4S00A 4U6WA 4PNCA 3IU8A 3CB5A 1R5GA 2NQ7A 1XNZA 1W7VA 2BHDA 1XGOA 1QXYA 2EVCA 4FUKA 4IECA 4IU6A 2EA4A 1WL6A 4IKUA 1C27A 5CDEA 4FO7A 1M35A 2NQ6A 3PKEA 2BN7A 4FO8A 4R60A 2P99A 3L24A 4S2TP 1MATA 3RVAA 2BWSA 1WKMA 1JAWA 1YVMA 2GG8A 2IW2A 2BHCA 3FMRA 3BITA 2GU6A 2G6PA 1WY2A 1B6AA 4ZNGA 2GG3A 3FMQA 4U6JA 2P98A 4U69A 1W2MA 5CDVA 4IKSA 1Y1NA 4FLIA 1C23A 2OAZA 1R58A 3CB6A 3MATA 4QR8A 2V6CA 3PKCA 5CE6A 4RZYA 1WBQA 3Q6DA 2BWWA 2GGBA 2V3YA 1O0XA 2BHAA 2GG2A 2B3LA 3TB5A 1CHMA 4RZZA 4IDYA 1WN1A 4FLKA 1KQ9A 5E5BA 5JI6A 1YW7A 4U76A 1WLRA 3BIQA 2GU7A 4FLJA 2GGCA 2V3XA 1QZYA 3FM3A 2BWVA 2GU5A 5CDLA 1KP0A 3CTZA 2Q8KA 3MX6A 2Q96A 3PKAA 5JFRA 4FKCA 2GZ5A 1A16A 1WL9A 2Q93A 4U6ZA 2Q95A 4JUQA 3PKBA 4ZWPA 4FLLA 4ZWOA 4S2RP 1KQ0A 2BHBA 1C21A 4KM3A 2MATA 2V3ZA 2BWYA 1YW9A 3IU9A 4S01A 4U6EA 1QXZA 1C22A 2GG7A 2BWTA 4RGZ1 4U6CA 5FCHA 4U71A 5FCFA 2EVMA 1XGSA 1C24A 2Q94A 2EA2A 2B3HA 2HOWA 1YW8A 2BH3A 2BWUA 4MATA 4U75A 1BOAA 1R5HA 3L7GA 2Q92A 1PV9A 4IKTA 2EVOA 2GA2A 3PKDA 1B59A 2GU4A 4U1BA 3IG4A 4IF7A 5CNXA 3RORA 1N51A 2OKNA 1YJ3A 4Z7MA
chains in the Genus database with same CATH topology
4PV4A 2BWXA 2GG5A 5D6FA 5CLSA 1QXWA 4IKRA 3S6BA 2GTXA 4A6VA 2GG0A 3MR1A 1XGMA 3TAVA 4U70A 2BB7A 4HXXA 4EGEA 5CIKA 3IU7A 4IPAA 5JHUA 5D6EA 2DFIA 1BN5A 3D27A 2ADUA 2B3KA 2ZSGA 4ZWUA 4A6WA 2P9AA 1XGNA 4U73A 4B28A 3BIPA 4OOKA 2GG9A 4S00A 4U6WA 4PNCA 3IU8A 3CB5A 1R5GA 2NQ7A 1XNZA 1W7VA 2BHDA 1XGOA 1QXYA 2EVCA 4FUKA 4IECA 4IU6A 2EA4A 1WL6A 4IKUA 1C27A 5CDEA 4FO7A 1M35A 2NQ6A 3PKEA 2BN7A 4FO8A 4R60A 2P99A 3L24A 4S2TP 1MATA 3RVAA 2BWSA 1WKMA 1JAWA 1YVMA 2GG8A 2IW2A 2BHCA 3FMRA 3BITA 2GU6A 2G6PA 1WY2A 1B6AA 4ZNGA 2GG3A 3FMQA 4U6JA 2P98A 4U69A 1W2MA 5CDVA 4IKSA 1Y1NA 4FLIA 1C23A 2OAZA 1R58A 3CB6A 3MATA 4QR8A 2V6CA 3PKCA 5CE6A 4RZYA 1WBQA 3Q6DA 2BWWA 2GGBA 2V3YA 1O0XA 2BHAA 2GG2A 2B3LA 3TB5A 1CHMA 4RZZA 4IDYA 1WN1A 4FLKA 1KQ9A 5E5BA 5JI6A 1YW7A 4U76A 1WLRA 3BIQA 2GU7A 4FLJA 2GGCA 2V3XA 1QZYA 3FM3A 2BWVA 2GU5A 5CDLA 1KP0A 3CTZA 2Q8KA 3MX6A 2Q96A 3PKAA 5JFRA 4FKCA 2GZ5A 1A16A 1WL9A 2Q93A 4U6ZA 2Q95A 4JUQA 3PKBA 4ZWPA 4FLLA 4ZWOA 4S2RP 1KQ0A 2BHBA 1C21A 4KM3A 2MATA 2V3ZA 2BWYA 1YW9A 3IU9A 4S01A 4U6EA 1QXZA 1C22A 2GG7A 2BWTA 4RGZ1 4U6CA 5FCHA 4U71A 5FCFA 2EVMA 1XGSA 1C24A 2Q94A 2EA2A 2B3HA 2HOWA 1YW8A 2BH3A 2BWUA 4MATA 4U75A 1BOAA 1R5HA 3L7GA 2Q92A 1PV9A 4IKTA 2EVOA 2GA2A 3PKDA 1B59A 2GU4A 4U1BA 3IG4A 4IF7A 5CNXA 3RORA 1N51A 2OKNA 1YJ3A 4Z7MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4PV4 A;  2BWX A;  2GG5 A;  5D6F A;  5CLS A;  1QXW A;  4IKR A;  3S6B A;  2GTX A;  4A6V A;  2GG0 A;  3MR1 A;  1XGM A;  3TAV A;  4U70 A;  2BB7 A;  4HXX A;  4EGE A;  5CIK A;  3IU7 A;  4IPA A;  5JHU A;  5D6E A;  2DFI A;  1BN5 A;  3D27 A;  2ADU A;  2B3K A;  2ZSG A;  4ZWU A;  4A6W A;  2P9A A;  1XGN A;  4U73 A;  4B28 A;  3BIP A;  4OOK A;  2GG9 A;  4S00 A;  4U6W A;  4PNC A;  3IU8 A;  3CB5 A;  1R5G A;  2NQ7 A;  1XNZ A;  1W7V A;  2BHD A;  1XGO A;  1QXY A;  2EVC A;  4FUK A;  4IEC A;  4IU6 A;  2EA4 A;  1WL6 A;  4IKU A;  1C27 A;  5CDE A;  4FO7 A;  1M35 A;  2NQ6 A;  3PKE A;  2BN7 A;  4FO8 A;  4R60 A;  2P99 A;  3L24 A;  4S2T P;  1MAT A;  3RVA A;  2BWS A;  1WKM A;  1JAW A;  1YVM A;  2GG8 A;  2IW2 A;  2BHC A;  3FMR A;  3BIT A;  2GU6 A;  2G6P A;  1WY2 A;  1B6A A;  4ZNG A;  2GG3 A;  3FMQ A;  4U6J A;  2P98 A;  4U69 A;  1W2M A;  5CDV A;  4IKS A;  1Y1N A;  4FLI A;  1C23 A;  2OAZ A;  1R58 A;  3CB6 A;  3MAT A;  4QR8 A;  2V6C A;  3PKC A;  5CE6 A;  4RZY A;  1WBQ A;  3Q6D A;  2BWW A;  2GGB A;  2V3Y A;  1O0X A;  2BHA A;  2GG2 A;  2B3L A;  3TB5 A;  1CHM A;  4RZZ A;  4IDY A;  1WN1 A;  4FLK A;  1KQ9 A;  5E5B A;  5JI6 A;  1YW7 A;  4U76 A;  1WLR A;  3BIQ A;  2GU7 A;  4FLJ A;  2GGC A;  2V3X A;  1QZY A;  3FM3 A;  2BWV A;  2GU5 A;  5CDL A;  1KP0 A;  3CTZ A;  2Q8K A;  3MX6 A;  2Q96 A;  3PKA A;  5JFR A;  4FKC A;  2GZ5 A;  1A16 A;  1WL9 A;  2Q93 A;  4U6Z A;  2Q95 A;  4JUQ A;  3PKB A;  4ZWP A;  4FLL A;  4ZWO A;  4S2R P;  1KQ0 A;  2BHB A;  1C21 A;  4KM3 A;  2MAT A;  2V3Z A;  2BWY A;  1YW9 A;  3IU9 A;  4S01 A;  4U6E A;  1QXZ A;  1C22 A;  2GG7 A;  2BWT A;  4RGZ 1;  4U6C A;  5FCH A;  4U71 A;  5FCF A;  2EVM A;  1XGS A;  1C24 A;  2Q94 A;  2EA2 A;  2B3H A;  2HOW A;  1YW8 A;  2BH3 A;  2BWU A;  4MAT A;  4U75 A;  1BOA A;  1R5H A;  3L7G A;  2Q92 A;  1PV9 A;  4IKT A;  2EVO A;  2GA2 A;  3PKD A;  1B59 A;  2GU4 A;  4U1B A;  3IG4 A;  4IF7 A;  5CNX A;  3ROR A;  1N51 A;  2OKN A;  1YJ3 A;  4Z7M A; 
#chains in the Genus database with same CATH topology
 4PV4 A;  2BWX A;  2GG5 A;  5D6F A;  5CLS A;  1QXW A;  4IKR A;  3S6B A;  2GTX A;  4A6V A;  2GG0 A;  3MR1 A;  1XGM A;  3TAV A;  4U70 A;  2BB7 A;  4HXX A;  4EGE A;  5CIK A;  3IU7 A;  4IPA A;  5JHU A;  5D6E A;  2DFI A;  1BN5 A;  3D27 A;  2ADU A;  2B3K A;  2ZSG A;  4ZWU A;  4A6W A;  2P9A A;  1XGN A;  4U73 A;  4B28 A;  3BIP A;  4OOK A;  2GG9 A;  4S00 A;  4U6W A;  4PNC A;  3IU8 A;  3CB5 A;  1R5G A;  2NQ7 A;  1XNZ A;  1W7V A;  2BHD A;  1XGO A;  1QXY A;  2EVC A;  4FUK A;  4IEC A;  4IU6 A;  2EA4 A;  1WL6 A;  4IKU A;  1C27 A;  5CDE A;  4FO7 A;  1M35 A;  2NQ6 A;  3PKE A;  2BN7 A;  4FO8 A;  4R60 A;  2P99 A;  3L24 A;  4S2T P;  1MAT A;  3RVA A;  2BWS A;  1WKM A;  1JAW A;  1YVM A;  2GG8 A;  2IW2 A;  2BHC A;  3FMR A;  3BIT A;  2GU6 A;  2G6P A;  1WY2 A;  1B6A A;  4ZNG A;  2GG3 A;  3FMQ A;  4U6J A;  2P98 A;  4U69 A;  1W2M A;  5CDV A;  4IKS A;  1Y1N A;  4FLI A;  1C23 A;  2OAZ A;  1R58 A;  3CB6 A;  3MAT A;  4QR8 A;  2V6C A;  3PKC A;  5CE6 A;  4RZY A;  1WBQ A;  3Q6D A;  2BWW A;  2GGB A;  2V3Y A;  1O0X A;  2BHA A;  2GG2 A;  2B3L A;  3TB5 A;  1CHM A;  4RZZ A;  4IDY A;  1WN1 A;  4FLK A;  1KQ9 A;  5E5B A;  5JI6 A;  1YW7 A;  4U76 A;  1WLR A;  3BIQ A;  2GU7 A;  4FLJ A;  2GGC A;  2V3X A;  1QZY A;  3FM3 A;  2BWV A;  2GU5 A;  5CDL A;  1KP0 A;  3CTZ A;  2Q8K A;  3MX6 A;  2Q96 A;  3PKA A;  5JFR A;  4FKC A;  2GZ5 A;  1A16 A;  1WL9 A;  2Q93 A;  4U6Z A;  2Q95 A;  4JUQ A;  3PKB A;  4ZWP A;  4FLL A;  4ZWO A;  4S2R P;  1KQ0 A;  2BHB A;  1C21 A;  4KM3 A;  2MAT A;  2V3Z A;  2BWY A;  1YW9 A;  3IU9 A;  4S01 A;  4U6E A;  1QXZ A;  1C22 A;  2GG7 A;  2BWT A;  4RGZ 1;  4U6C A;  5FCH A;  4U71 A;  5FCF A;  2EVM A;  1XGS A;  1C24 A;  2Q94 A;  2EA2 A;  2B3H A;  2HOW A;  1YW8 A;  2BH3 A;  2BWU A;  4MAT A;  4U75 A;  1BOA A;  1R5H A;  3L7G A;  2Q92 A;  1PV9 A;  4IKT A;  2EVO A;  2GA2 A;  3PKD A;  1B59 A;  2GU4 A;  4U1B A;  3IG4 A;  4IF7 A;  5CNX A;  3ROR A;  1N51 A;  2OKN A;  1YJ3 A;  4Z7M A; 
#chains in the Genus database with same CATH homology
 4PV4 A;  2BWX A;  2GG5 A;  5D6F A;  5CLS A;  1QXW A;  4IKR A;  3S6B A;  2GTX A;  4A6V A;  2GG0 A;  3MR1 A;  1XGM A;  3TAV A;  4U70 A;  2BB7 A;  4HXX A;  4EGE A;  5CIK A;  3IU7 A;  4IPA A;  5JHU A;  5D6E A;  2DFI A;  1BN5 A;  3D27 A;  2ADU A;  2B3K A;  2ZSG A;  4ZWU A;  4A6W A;  2P9A A;  1XGN A;  4U73 A;  4B28 A;  3BIP A;  4OOK A;  2GG9 A;  4S00 A;  4U6W A;  4PNC A;  3IU8 A;  3CB5 A;  1R5G A;  2NQ7 A;  1XNZ A;  1W7V A;  2BHD A;  1XGO A;  1QXY A;  2EVC A;  4FUK A;  4IEC A;  4IU6 A;  2EA4 A;  1WL6 A;  4IKU A;  1C27 A;  5CDE A;  4FO7 A;  1M35 A;  2NQ6 A;  3PKE A;  2BN7 A;  4FO8 A;  4R60 A;  2P99 A;  3L24 A;  4S2T P;  1MAT A;  3RVA A;  2BWS A;  1WKM A;  1JAW A;  1YVM A;  2GG8 A;  2IW2 A;  2BHC A;  3FMR A;  3BIT A;  2GU6 A;  2G6P A;  1WY2 A;  1B6A A;  4ZNG A;  2GG3 A;  3FMQ A;  4U6J A;  2P98 A;  4U69 A;  1W2M A;  5CDV A;  4IKS A;  1Y1N A;  4FLI A;  1C23 A;  2OAZ A;  1R58 A;  3CB6 A;  3MAT A;  4QR8 A;  2V6C A;  3PKC A;  5CE6 A;  4RZY A;  1WBQ A;  3Q6D A;  2BWW A;  2GGB A;  2V3Y A;  1O0X A;  2BHA A;  2GG2 A;  2B3L A;  3TB5 A;  1CHM A;  4RZZ A;  4IDY A;  1WN1 A;  4FLK A;  1KQ9 A;  5E5B A;  5JI6 A;  1YW7 A;  4U76 A;  1WLR A;  3BIQ A;  2GU7 A;  4FLJ A;  2GGC A;  2V3X A;  1QZY A;  3FM3 A;  2BWV A;  2GU5 A;  5CDL A;  1KP0 A;  3CTZ A;  2Q8K A;  3MX6 A;  2Q96 A;  3PKA A;  5JFR A;  4FKC A;  2GZ5 A;  1A16 A;  1WL9 A;  2Q93 A;  4U6Z A;  2Q95 A;  4JUQ A;  3PKB A;  4ZWP A;  4FLL A;  4ZWO A;  4S2R P;  1KQ0 A;  2BHB A;  1C21 A;  4KM3 A;  2MAT A;  2V3Z A;  2BWY A;  1YW9 A;  3IU9 A;  4S01 A;  4U6E A;  1QXZ A;  1C22 A;  2GG7 A;  2BWT A;  4RGZ 1;  4U6C A;  5FCH A;  4U71 A;  5FCF A;  2EVM A;  1XGS A;  1C24 A;  2Q94 A;  2EA2 A;  2B3H A;  2HOW A;  1YW8 A;  2BH3 A;  2BWU A;  4MAT A;  4U75 A;  1BOA A;  1R5H A;  3L7G A;  2Q92 A;  1PV9 A;  4IKT A;  2EVO A;  2GA2 A;  3PKD A;  1B59 A;  2GU4 A;  4U1B A;  3IG4 A;  4IF7 A;  5CNX A;  3ROR A;  1N51 A;  2OKN A;  1YJ3 A;  4Z7M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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