5FCFA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and mn bound
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
397
structure length
397
Chain Sequence
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 136
structure length 397
sequence length 397
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fcfA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fcfA02
4FLIA 1XGMA 4FLKA 2NQ6A 5JFRA 4FO8A 1R5GA 5D6EA 1JAWA 1XGOA 4Z7MA 5CDEA 4OOKA 2Q93A 5CDLA 3TAVA 3FM3A 1PV9A 5FCHA 1QXYA 1YW7A 3PKEA 4A6WA 2MATA 4ZNGA 4IDYA 1W7VA 2ZSGA 1CHMA 3S6BA 1M35A 4IECA 2B3HA 3CB6A 4FLJA 4U70A 1R5HA 3PKBA 3IG4A 3CB5A 1BOAA 4IF7A 4MATA 1Y1NA 5CNXA 2OKNA 3PN9A 1QXZA 4U76A 2BH3A 2ADUA 2GG7A 1MATA 4QR8A 5CE6A 4ZWUA 2P98A 1XGSA 2GZ5A 1C27A 1WBQA 2BWWA 2GGCA 1XNZA 1QZYA 4EGEA 4FKCA 1WL6A 1YVMA 2P99A 4U6CA 1C23A 4ZWPA 3MX6A 4U6JA 2BWSA 4RZYA 1KQ9A 2BN7A 1WL9A 3D27A 3PKCA 5JHUA 2BHAA 3BIQA 2BHDA 4FLLA 3PKAA 4IKTA 1YW8A 2EA2A 3IU9A 2GU6A 2GG3A 4A6VA 1WLRA 2GG0A 2GTXA 2DFIA 2GU5A 2BWXA 2B3LA 3Q6DA 2V6CA 1YJ3A 1W2MA 1QXWA 3PEBA 4JUQA 1WKMA 5CDVA 5CLSA 2G6PA 2B3KA 2GG8A 3OOOA 2GU7A 1O0XA 2EVCA 2GGBA 1B6AA 4IKUA 1C22A 2GG9A 2Q94A 4U71A 1WY2A 2BWUA 4S01A 2Q8KA 4B28A 5JI6A 3RVAA 2V3XA 4ZWOA 4S2RP 5FCFA 2Q92A 4KM3A 3BITA 1BN5A 2EVMA 1KP0A 1N51A 3IL0A 2NQ7A 2BWYA 1KQ0A 3L24A 1YW9A 2Q95A 4U6EA 3TB5A 1WN1A 1C24A 2V3YA 2EVOA 4R60A 2GU4A 4FO7A 5CIKA 5E5BA 3I7MA 4U75A 4IKSA 4IU6A 4PV4A 3MR1A 4S2TP 2BHBA 1XGNA 2P9AA 2IW2A 2EA4A 1R58A 4S00A 2HOWA 3BIPA 3FMQA 1B59A 3OVKA 4U6ZA 3QOCA 5E2CA 4HXXA 2GG5A 3L7GA 4FUKA 2V3ZA 4U69A 4U6WA 4IPAA 2BWTA 3O5VA 3IU7A 2BWVA 2BB7A 2OAZA 4RZZA 3CTZA 3PKDA 4RGZ1 1A16A 2GA2A 3RORA 4PNCA 3IU8A 2Q96A 5D6FA 2GG2A 3FMRA 2BHCA 3MATA 4U1BA 1C21A 4IKRA 4U73A
chains in the Genus database with same CATH superfamily
4FLIA 1XGMA 4FLKA 2NQ6A 5JFRA 4FO8A 1R5GA 5D6EA 1JAWA 1XGOA 4Z7MA 5CDEA 4OOKA 2Q93A 5CDLA 3TAVA 3FM3A 1PV9A 5FCHA 1QXYA 1YW7A 3PKEA 4A6WA 2MATA 4ZNGA 4IDYA 1W7VA 2ZSGA 1CHMA 3S6BA 1M35A 4IECA 2B3HA 3CB6A 4FLJA 4U70A 1R5HA 3PKBA 3IG4A 3CB5A 1BOAA 4IF7A 4MATA 1Y1NA 5CNXA 2OKNA 3PN9A 1QXZA 4U76A 2BH3A 2ADUA 2GG7A 1MATA 4QR8A 5CE6A 4ZWUA 2P98A 1XGSA 2GZ5A 1C27A 1WBQA 2BWWA 2GGCA 1XNZA 1QZYA 4EGEA 4FKCA 1WL6A 1YVMA 2P99A 4U6CA 1C23A 4ZWPA 3MX6A 4U6JA 2BWSA 4RZYA 1KQ9A 2BN7A 1WL9A 3D27A 3PKCA 5JHUA 2BHAA 3BIQA 2BHDA 4FLLA 3PKAA 4IKTA 1YW8A 2EA2A 3IU9A 2GU6A 2GG3A 4A6VA 1WLRA 2GG0A 2GTXA 2DFIA 2GU5A 2BWXA 2B3LA 3Q6DA 2V6CA 1YJ3A 1W2MA 1QXWA 3PEBA 4JUQA 1WKMA 5CDVA 5CLSA 2G6PA 2B3KA 2GG8A 3OOOA 2GU7A 1O0XA 2EVCA 2GGBA 1B6AA 4IKUA 1C22A 2GG9A 2Q94A 4U71A 1WY2A 2BWUA 4S01A 2Q8KA 4B28A 5JI6A 3RVAA 2V3XA 4ZWOA 4S2RP 5FCFA 2Q92A 4KM3A 3BITA 1BN5A 2EVMA 1KP0A 1N51A 3IL0A 2NQ7A 2BWYA 1KQ0A 3L24A 1YW9A 2Q95A 4U6EA 3TB5A 1WN1A 1C24A 2V3YA 2EVOA 4R60A 2GU4A 4FO7A 5CIKA 5E5BA 3I7MA 4U75A 4IKSA 4IU6A 4PV4A 3MR1A 4S2TP 2BHBA 1XGNA 2P9AA 2IW2A 2EA4A 1R58A 4S00A 2HOWA 3BIPA 3FMQA 1B59A 3OVKA 4U6ZA 3QOCA 5E2CA 4HXXA 2GG5A 3L7GA 4FUKA 2V3ZA 4U69A 4U6WA 4IPAA 2BWTA 3O5VA 3IU7A 2BWVA 2BB7A 2OAZA 4RZZA 3CTZA 3PKDA 4RGZ1 1A16A 2GA2A 3RORA 4PNCA 3IU8A 2Q96A 5D6FA 2GG2A 3FMRA 2BHCA 3MATA 4U1BA 1C21A 4IKRA 4U73A
chains in the Genus database with same CATH topology
4FLIA 1XGMA 4FLKA 2NQ6A 5JFRA 4FO8A 1R5GA 5D6EA 1JAWA 1XGOA 4Z7MA 5CDEA 4OOKA 2Q93A 5CDLA 3TAVA 3FM3A 1PV9A 5FCHA 1QXYA 1YW7A 3PKEA 4A6WA 2MATA 4ZNGA 4IDYA 1W7VA 2ZSGA 1CHMA 3S6BA 1M35A 4IECA 2B3HA 3CB6A 4FLJA 4U70A 1R5HA 3PKBA 3IG4A 3CB5A 1BOAA 4IF7A 4MATA 1Y1NA 5CNXA 2OKNA 3PN9A 1QXZA 4U76A 2BH3A 2ADUA 2GG7A 1MATA 4QR8A 5CE6A 4ZWUA 2P98A 1XGSA 2GZ5A 1C27A 1WBQA 2BWWA 2GGCA 1XNZA 1QZYA 4EGEA 4FKCA 1WL6A 1YVMA 2P99A 4U6CA 1C23A 4ZWPA 3MX6A 4U6JA 2BWSA 4RZYA 1KQ9A 2BN7A 1WL9A 3D27A 3PKCA 5JHUA 2BHAA 3BIQA 2BHDA 4FLLA 3PKAA 4IKTA 1YW8A 2EA2A 3IU9A 2GU6A 2GG3A 4A6VA 1WLRA 2GG0A 2GTXA 2DFIA 2GU5A 2BWXA 2B3LA 3Q6DA 2V6CA 1YJ3A 1W2MA 1QXWA 3PEBA 4JUQA 1WKMA 5CDVA 5CLSA 2G6PA 2B3KA 2GG8A 3OOOA 2GU7A 1O0XA 2EVCA 2GGBA 1B6AA 4IKUA 1C22A 2GG9A 2Q94A 4U71A 1WY2A 2BWUA 4S01A 2Q8KA 4B28A 5JI6A 3RVAA 2V3XA 4ZWOA 4S2RP 5FCFA 2Q92A 4KM3A 3BITA 1BN5A 2EVMA 1KP0A 1N51A 3IL0A 2NQ7A 2BWYA 1KQ0A 3L24A 1YW9A 2Q95A 4U6EA 3TB5A 1WN1A 1C24A 2V3YA 2EVOA 4R60A 2GU4A 4FO7A 5CIKA 5E5BA 3I7MA 4U75A 4IKSA 4IU6A 4PV4A 3MR1A 4S2TP 2BHBA 1XGNA 2P9AA 2IW2A 2EA4A 1R58A 4S00A 2HOWA 3BIPA 3FMQA 1B59A 3OVKA 4U6ZA 3QOCA 5E2CA 4HXXA 2GG5A 3L7GA 4FUKA 2V3ZA 4U69A 4U6WA 4IPAA 2BWTA 3O5VA 3IU7A 2BWVA 2BB7A 2OAZA 4RZZA 3CTZA 3PKDA 4RGZ1 1A16A 2GA2A 3RORA 4PNCA 3IU8A 2Q96A 5D6FA 2GG2A 3FMRA 2BHCA 3MATA 4U1BA 1C21A 4IKRA 4U73A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FLI A;  1XGM A;  4FLK A;  2NQ6 A;  5JFR A;  4FO8 A;  1R5G A;  5D6E A;  1JAW A;  1XGO A;  4Z7M A;  5CDE A;  4OOK A;  2Q93 A;  5CDL A;  3TAV A;  3FM3 A;  1PV9 A;  5FCH A;  1QXY A;  1YW7 A;  3PKE A;  4A6W A;  2MAT A;  4ZNG A;  4IDY A;  1W7V A;  2ZSG A;  1CHM A;  3S6B A;  1M35 A;  4IEC A;  2B3H A;  3CB6 A;  4FLJ A;  4U70 A;  1R5H A;  3PKB A;  3IG4 A;  3CB5 A;  1BOA A;  4IF7 A;  4MAT A;  1Y1N A;  5CNX A;  2OKN A;  3PN9 A;  1QXZ A;  4U76 A;  2BH3 A;  2ADU A;  2GG7 A;  1MAT A;  4QR8 A;  5CE6 A;  4ZWU A;  2P98 A;  1XGS A;  2GZ5 A;  1C27 A;  1WBQ A;  2BWW A;  2GGC A;  1XNZ A;  1QZY A;  4EGE A;  4FKC A;  1WL6 A;  1YVM A;  2P99 A;  4U6C A;  1C23 A;  4ZWP A;  3MX6 A;  4U6J A;  2BWS A;  4RZY A;  1KQ9 A;  2BN7 A;  1WL9 A;  3D27 A;  3PKC A;  5JHU A;  2BHA A;  3BIQ A;  2BHD A;  4FLL A;  3PKA A;  4IKT A;  1YW8 A;  2EA2 A;  3IU9 A;  2GU6 A;  2GG3 A;  4A6V A;  1WLR A;  2GG0 A;  2GTX A;  2DFI A;  2GU5 A;  2BWX A;  2B3L A;  3Q6D A;  2V6C A;  1YJ3 A;  1W2M A;  1QXW A;  3PEB A;  4JUQ A;  1WKM A;  5CDV A;  5CLS A;  2G6P A;  2B3K A;  2GG8 A;  3OOO A;  2GU7 A;  1O0X A;  2EVC A;  2GGB A;  1B6A A;  4IKU A;  1C22 A;  2GG9 A;  2Q94 A;  4U71 A;  1WY2 A;  2BWU A;  4S01 A;  2Q8K A;  4B28 A;  5JI6 A;  3RVA A;  2V3X A;  4ZWO A;  4S2R P;  5FCF A;  2Q92 A;  4KM3 A;  3BIT A;  1BN5 A;  2EVM A;  1KP0 A;  1N51 A;  3IL0 A;  2NQ7 A;  2BWY A;  1KQ0 A;  3L24 A;  1YW9 A;  2Q95 A;  4U6E A;  3TB5 A;  1WN1 A;  1C24 A;  2V3Y A;  2EVO A;  4R60 A;  2GU4 A;  4FO7 A;  5CIK A;  5E5B A;  3I7M A;  4U75 A;  4IKS A;  4IU6 A;  4PV4 A;  3MR1 A;  4S2T P;  2BHB A;  1XGN A;  2P9A A;  2IW2 A;  2EA4 A;  1R58 A;  4S00 A;  2HOW A;  3BIP A;  3FMQ A;  1B59 A;  3OVK A;  4U6Z A;  3QOC A;  5E2C A;  4HXX A;  2GG5 A;  3L7G A;  4FUK A;  2V3Z A;  4U69 A;  4U6W A;  4IPA A;  2BWT A;  3O5V A;  3IU7 A;  2BWV A;  2BB7 A;  2OAZ A;  4RZZ A;  3CTZ A;  3PKD A;  4RGZ 1;  1A16 A;  2GA2 A;  3ROR A;  4PNC A;  3IU8 A;  2Q96 A;  5D6F A;  2GG2 A;  3FMR A;  2BHC A;  3MAT A;  4U1B A;  1C21 A;  4IKR A;  4U73 A; 
#chains in the Genus database with same CATH topology
 4FLI A;  1XGM A;  4FLK A;  2NQ6 A;  5JFR A;  4FO8 A;  1R5G A;  5D6E A;  1JAW A;  1XGO A;  4Z7M A;  5CDE A;  4OOK A;  2Q93 A;  5CDL A;  3TAV A;  3FM3 A;  1PV9 A;  5FCH A;  1QXY A;  1YW7 A;  3PKE A;  4A6W A;  2MAT A;  4ZNG A;  4IDY A;  1W7V A;  2ZSG A;  1CHM A;  3S6B A;  1M35 A;  4IEC A;  2B3H A;  3CB6 A;  4FLJ A;  4U70 A;  1R5H A;  3PKB A;  3IG4 A;  3CB5 A;  1BOA A;  4IF7 A;  4MAT A;  1Y1N A;  5CNX A;  2OKN A;  3PN9 A;  1QXZ A;  4U76 A;  2BH3 A;  2ADU A;  2GG7 A;  1MAT A;  4QR8 A;  5CE6 A;  4ZWU A;  2P98 A;  1XGS A;  2GZ5 A;  1C27 A;  1WBQ A;  2BWW A;  2GGC A;  1XNZ A;  1QZY A;  4EGE A;  4FKC A;  1WL6 A;  1YVM A;  2P99 A;  4U6C A;  1C23 A;  4ZWP A;  3MX6 A;  4U6J A;  2BWS A;  4RZY A;  1KQ9 A;  2BN7 A;  1WL9 A;  3D27 A;  3PKC A;  5JHU A;  2BHA A;  3BIQ A;  2BHD A;  4FLL A;  3PKA A;  4IKT A;  1YW8 A;  2EA2 A;  3IU9 A;  2GU6 A;  2GG3 A;  4A6V A;  1WLR A;  2GG0 A;  2GTX A;  2DFI A;  2GU5 A;  2BWX A;  2B3L A;  3Q6D A;  2V6C A;  1YJ3 A;  1W2M A;  1QXW A;  3PEB A;  4JUQ A;  1WKM A;  5CDV A;  5CLS A;  2G6P A;  2B3K A;  2GG8 A;  3OOO A;  2GU7 A;  1O0X A;  2EVC A;  2GGB A;  1B6A A;  4IKU A;  1C22 A;  2GG9 A;  2Q94 A;  4U71 A;  1WY2 A;  2BWU A;  4S01 A;  2Q8K A;  4B28 A;  5JI6 A;  3RVA A;  2V3X A;  4ZWO A;  4S2R P;  5FCF A;  2Q92 A;  4KM3 A;  3BIT A;  1BN5 A;  2EVM A;  1KP0 A;  1N51 A;  3IL0 A;  2NQ7 A;  2BWY A;  1KQ0 A;  3L24 A;  1YW9 A;  2Q95 A;  4U6E A;  3TB5 A;  1WN1 A;  1C24 A;  2V3Y A;  2EVO A;  4R60 A;  2GU4 A;  4FO7 A;  5CIK A;  5E5B A;  3I7M A;  4U75 A;  4IKS A;  4IU6 A;  4PV4 A;  3MR1 A;  4S2T P;  2BHB A;  1XGN A;  2P9A A;  2IW2 A;  2EA4 A;  1R58 A;  4S00 A;  2HOW A;  3BIP A;  3FMQ A;  1B59 A;  3OVK A;  4U6Z A;  3QOC A;  5E2C A;  4HXX A;  2GG5 A;  3L7G A;  4FUK A;  2V3Z A;  4U69 A;  4U6W A;  4IPA A;  2BWT A;  3O5V A;  3IU7 A;  2BWV A;  2BB7 A;  2OAZ A;  4RZZ A;  3CTZ A;  3PKD A;  4RGZ 1;  1A16 A;  2GA2 A;  3ROR A;  4PNC A;  3IU8 A;  2Q96 A;  5D6F A;  2GG2 A;  3FMR A;  2BHC A;  3MAT A;  4U1B A;  1C21 A;  4IKR A;  4U73 A; 
#chains in the Genus database with same CATH homology
 4FLI A;  1XGM A;  4FLK A;  2NQ6 A;  5JFR A;  4FO8 A;  1R5G A;  5D6E A;  1JAW A;  1XGO A;  4Z7M A;  5CDE A;  4OOK A;  2Q93 A;  5CDL A;  3TAV A;  3FM3 A;  1PV9 A;  5FCH A;  1QXY A;  1YW7 A;  3PKE A;  4A6W A;  2MAT A;  4ZNG A;  4IDY A;  1W7V A;  2ZSG A;  1CHM A;  3S6B A;  1M35 A;  4IEC A;  2B3H A;  3CB6 A;  4FLJ A;  4U70 A;  1R5H A;  3PKB A;  3IG4 A;  3CB5 A;  1BOA A;  4IF7 A;  4MAT A;  1Y1N A;  5CNX A;  2OKN A;  3PN9 A;  1QXZ A;  4U76 A;  2BH3 A;  2ADU A;  2GG7 A;  1MAT A;  4QR8 A;  5CE6 A;  4ZWU A;  2P98 A;  1XGS A;  2GZ5 A;  1C27 A;  1WBQ A;  2BWW A;  2GGC A;  1XNZ A;  1QZY A;  4EGE A;  4FKC A;  1WL6 A;  1YVM A;  2P99 A;  4U6C A;  1C23 A;  4ZWP A;  3MX6 A;  4U6J A;  2BWS A;  4RZY A;  1KQ9 A;  2BN7 A;  1WL9 A;  3D27 A;  3PKC A;  5JHU A;  2BHA A;  3BIQ A;  2BHD A;  4FLL A;  3PKA A;  4IKT A;  1YW8 A;  2EA2 A;  3IU9 A;  2GU6 A;  2GG3 A;  4A6V A;  1WLR A;  2GG0 A;  2GTX A;  2DFI A;  2GU5 A;  2BWX A;  2B3L A;  3Q6D A;  2V6C A;  1YJ3 A;  1W2M A;  1QXW A;  3PEB A;  4JUQ A;  1WKM A;  5CDV A;  5CLS A;  2G6P A;  2B3K A;  2GG8 A;  3OOO A;  2GU7 A;  1O0X A;  2EVC A;  2GGB A;  1B6A A;  4IKU A;  1C22 A;  2GG9 A;  2Q94 A;  4U71 A;  1WY2 A;  2BWU A;  4S01 A;  2Q8K A;  4B28 A;  5JI6 A;  3RVA A;  2V3X A;  4ZWO A;  4S2R P;  5FCF A;  2Q92 A;  4KM3 A;  3BIT A;  1BN5 A;  2EVM A;  1KP0 A;  1N51 A;  3IL0 A;  2NQ7 A;  2BWY A;  1KQ0 A;  3L24 A;  1YW9 A;  2Q95 A;  4U6E A;  3TB5 A;  1WN1 A;  1C24 A;  2V3Y A;  2EVO A;  4R60 A;  2GU4 A;  4FO7 A;  5CIK A;  5E5B A;  3I7M A;  4U75 A;  4IKS A;  4IU6 A;  4PV4 A;  3MR1 A;  4S2T P;  2BHB A;  1XGN A;  2P9A A;  2IW2 A;  2EA4 A;  1R58 A;  4S00 A;  2HOW A;  3BIP A;  3FMQ A;  1B59 A;  3OVK A;  4U6Z A;  3QOC A;  5E2C A;  4HXX A;  2GG5 A;  3L7G A;  4FUK A;  2V3Z A;  4U69 A;  4U6W A;  4IPA A;  2BWT A;  3O5V A;  3IU7 A;  2BWV A;  2BB7 A;  2OAZ A;  4RZZ A;  3CTZ A;  3PKD A;  4RGZ 1;  1A16 A;  2GA2 A;  3ROR A;  4PNC A;  3IU8 A;  2Q96 A;  5D6F A;  2GG2 A;  3FMR A;  2BHC A;  3MAT A;  4U1B A;  1C21 A;  4IKR A;  4U73 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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