5FCFA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and mn bound
Total Genus 136
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
397
structure length
397
Chain Sequence
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
molecule keywords Proline dipeptidase
total genus 136
structure length 397
sequence length 397
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fcfA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fcfA02
4U6JA 3BIPA 2BWWA 4FO7A 2BH3A 4S2TP 1C21A 4U6WA 5JHUA 1R58A 3CB6A 2GG7A 2Q96A 3L24A 1YW8A 1CHMA 5E2CA 3PKCA 2GTXA 2Q8KA 4FLLA 2Q95A 4HXXA 3IL0A 4IECA 4ZNGA 2BB7A 4IKSA 1C23A 2GG5A 4IDYA 1YVMA 5E5BA 1WN1A 2P9AA 2Q92A 3QOCA 4S2RP 1C22A 1YJ3A 2GU7A 3RORA 4IKUA 5JI6A 2GGCA 2HOWA 2NQ7A 3PKBA 1N51A 4JUQA 1WL6A 2B3HA 4R60A 1WKMA 5CIKA 1O0XA 2EA4A 2V6CA 3MX6A 3TB5A 3FM3A 3I7MA 3IU7A 1Y1NA 3BITA 2BWYA 3TAVA 3IU9A 2BHBA 3OOOA 2G6PA 5CDVA 1YW7A 3D27A 4IPAA 3L7GA 2V3XA 5CDEA 4OOKA 1R5GA 1A16A 1W7VA 2V3ZA 4ZWPA 3PEBA 4ZWUA 1WBQA 2GG3A 2MATA 1WL9A 4MATA 2IW2A 2GA2A 4U75A 4IF7A 3RVAA 1XGOA 1KP0A 4ZWOA 2BWUA 1KQ9A 2P98A 2BHCA 2EVMA 2GG0A 2BHDA 2GGBA 1B59A 4IU6A 2V3YA 4PNCA 4EGEA 2BN7A 4FKCA 1W2MA 2GG2A 1XGSA 3FMRA 2BWVA 3OVKA 1QXYA 5FCFA 2Q94A 4U69A 4QR8A 3IU8A 2BWTA 2B3KA 1BOAA 2GG9A 3CB5A 2GU6A 4S01A 4U6EA 4Z7MA 2B3LA 2DFIA 1JAWA 4FLKA 2EVOA 1PV9A 2OAZA 3BIQA 3MATA 4RZYA 2P99A 3S6BA 2BWSA 2GU4A 1M35A 1XGMA 2Q93A 4RZZA 4S00A 2GG8A 5CDLA 3PKAA 4PV4A 3PKDA 2EA2A 1WY2A 3MR1A 4RGZ1 5FCHA 4U6ZA 4FLJA 3PN9A 2ZSGA 3FMQA 1MATA 5JFRA 2GZ5A 5D6EA 5CLSA 2OKNA 4IKRA 2BHAA 2EVCA 1R5HA 4B28A 5CE6A 1QXWA 1C24A 3Q6DA 1XNZA 2BWXA 1KQ0A 4U70A 3IG4A 2NQ6A 5D6FA 1QZYA 4U1BA 2GU5A 3O5VA 2ADUA 4IKTA 1BN5A 1XGNA 4U76A 4KM3A 4A6VA 1QXZA 1YW9A 4FUKA 4U73A 4FLIA 1C27A 5CNXA 4FO8A 4U6CA 1B6AA 3PKEA 4U71A 1WLRA 3CTZA 4A6WA
chains in the Genus database with same CATH superfamily
4U6JA 3BIPA 2BWWA 4FO7A 2BH3A 4S2TP 1C21A 4U6WA 5JHUA 1R58A 3CB6A 2GG7A 2Q96A 3L24A 1YW8A 1CHMA 5E2CA 3PKCA 2GTXA 2Q8KA 4FLLA 2Q95A 4HXXA 3IL0A 4IECA 4ZNGA 2BB7A 4IKSA 1C23A 2GG5A 4IDYA 1YVMA 5E5BA 1WN1A 2P9AA 2Q92A 3QOCA 4S2RP 1C22A 1YJ3A 2GU7A 3RORA 4IKUA 5JI6A 2GGCA 2HOWA 2NQ7A 3PKBA 1N51A 4JUQA 1WL6A 2B3HA 4R60A 1WKMA 5CIKA 1O0XA 2EA4A 2V6CA 3MX6A 3TB5A 3FM3A 3I7MA 3IU7A 1Y1NA 3BITA 2BWYA 3TAVA 3IU9A 2BHBA 3OOOA 2G6PA 5CDVA 1YW7A 3D27A 4IPAA 3L7GA 2V3XA 5CDEA 4OOKA 1R5GA 1A16A 1W7VA 2V3ZA 4ZWPA 3PEBA 4ZWUA 1WBQA 2GG3A 2MATA 1WL9A 4MATA 2IW2A 2GA2A 4U75A 4IF7A 3RVAA 1XGOA 1KP0A 4ZWOA 2BWUA 1KQ9A 2P98A 2BHCA 2EVMA 2GG0A 2BHDA 2GGBA 1B59A 4IU6A 2V3YA 4PNCA 4EGEA 2BN7A 4FKCA 1W2MA 2GG2A 1XGSA 3FMRA 2BWVA 3OVKA 1QXYA 5FCFA 2Q94A 4U69A 4QR8A 3IU8A 2BWTA 2B3KA 1BOAA 2GG9A 3CB5A 2GU6A 4S01A 4U6EA 4Z7MA 2B3LA 2DFIA 1JAWA 4FLKA 2EVOA 1PV9A 2OAZA 3BIQA 3MATA 4RZYA 2P99A 3S6BA 2BWSA 2GU4A 1M35A 1XGMA 2Q93A 4RZZA 4S00A 2GG8A 5CDLA 3PKAA 4PV4A 3PKDA 2EA2A 1WY2A 3MR1A 4RGZ1 5FCHA 4U6ZA 4FLJA 3PN9A 2ZSGA 3FMQA 1MATA 5JFRA 2GZ5A 5D6EA 5CLSA 2OKNA 4IKRA 2BHAA 2EVCA 1R5HA 4B28A 5CE6A 1QXWA 1C24A 3Q6DA 1XNZA 2BWXA 1KQ0A 4U70A 3IG4A 2NQ6A 5D6FA 1QZYA 4U1BA 2GU5A 3O5VA 2ADUA 4IKTA 1BN5A 1XGNA 4U76A 4KM3A 4A6VA 1QXZA 1YW9A 4FUKA 4U73A 4FLIA 1C27A 5CNXA 4FO8A 4U6CA 1B6AA 3PKEA 4U71A 1WLRA 3CTZA 4A6WA
chains in the Genus database with same CATH topology
4U6JA 3BIPA 2BWWA 4FO7A 2BH3A 4S2TP 1C21A 4U6WA 5JHUA 1R58A 3CB6A 2GG7A 2Q96A 3L24A 1YW8A 1CHMA 5E2CA 3PKCA 2GTXA 2Q8KA 4FLLA 2Q95A 4HXXA 3IL0A 4IECA 4ZNGA 2BB7A 4IKSA 1C23A 2GG5A 4IDYA 1YVMA 5E5BA 1WN1A 2P9AA 2Q92A 3QOCA 4S2RP 1C22A 1YJ3A 2GU7A 3RORA 4IKUA 5JI6A 2GGCA 2HOWA 2NQ7A 3PKBA 1N51A 4JUQA 1WL6A 2B3HA 4R60A 1WKMA 5CIKA 1O0XA 2EA4A 2V6CA 3MX6A 3TB5A 3FM3A 3I7MA 3IU7A 1Y1NA 3BITA 2BWYA 3TAVA 3IU9A 2BHBA 3OOOA 2G6PA 5CDVA 1YW7A 3D27A 4IPAA 3L7GA 2V3XA 5CDEA 4OOKA 1R5GA 1A16A 1W7VA 2V3ZA 4ZWPA 3PEBA 4ZWUA 1WBQA 2GG3A 2MATA 1WL9A 4MATA 2IW2A 2GA2A 4U75A 4IF7A 3RVAA 1XGOA 1KP0A 4ZWOA 2BWUA 1KQ9A 2P98A 2BHCA 2EVMA 2GG0A 2BHDA 2GGBA 1B59A 4IU6A 2V3YA 4PNCA 4EGEA 2BN7A 4FKCA 1W2MA 2GG2A 1XGSA 3FMRA 2BWVA 3OVKA 1QXYA 5FCFA 2Q94A 4U69A 4QR8A 3IU8A 2BWTA 2B3KA 1BOAA 2GG9A 3CB5A 2GU6A 4S01A 4U6EA 4Z7MA 2B3LA 2DFIA 1JAWA 4FLKA 2EVOA 1PV9A 2OAZA 3BIQA 3MATA 4RZYA 2P99A 3S6BA 2BWSA 2GU4A 1M35A 1XGMA 2Q93A 4RZZA 4S00A 2GG8A 5CDLA 3PKAA 4PV4A 3PKDA 2EA2A 1WY2A 3MR1A 4RGZ1 5FCHA 4U6ZA 4FLJA 3PN9A 2ZSGA 3FMQA 1MATA 5JFRA 2GZ5A 5D6EA 5CLSA 2OKNA 4IKRA 2BHAA 2EVCA 1R5HA 4B28A 5CE6A 1QXWA 1C24A 3Q6DA 1XNZA 2BWXA 1KQ0A 4U70A 3IG4A 2NQ6A 5D6FA 1QZYA 4U1BA 2GU5A 3O5VA 2ADUA 4IKTA 1BN5A 1XGNA 4U76A 4KM3A 4A6VA 1QXZA 1YW9A 4FUKA 4U73A 4FLIA 1C27A 5CNXA 4FO8A 4U6CA 1B6AA 3PKEA 4U71A 1WLRA 3CTZA 4A6WA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U6J A;  3BIP A;  2BWW A;  4FO7 A;  2BH3 A;  4S2T P;  1C21 A;  4U6W A;  5JHU A;  1R58 A;  3CB6 A;  2GG7 A;  2Q96 A;  3L24 A;  1YW8 A;  1CHM A;  5E2C A;  3PKC A;  2GTX A;  2Q8K A;  4FLL A;  2Q95 A;  4HXX A;  3IL0 A;  4IEC A;  4ZNG A;  2BB7 A;  4IKS A;  1C23 A;  2GG5 A;  4IDY A;  1YVM A;  5E5B A;  1WN1 A;  2P9A A;  2Q92 A;  3QOC A;  4S2R P;  1C22 A;  1YJ3 A;  2GU7 A;  3ROR A;  4IKU A;  5JI6 A;  2GGC A;  2HOW A;  2NQ7 A;  3PKB A;  1N51 A;  4JUQ A;  1WL6 A;  2B3H A;  4R60 A;  1WKM A;  5CIK A;  1O0X A;  2EA4 A;  2V6C A;  3MX6 A;  3TB5 A;  3FM3 A;  3I7M A;  3IU7 A;  1Y1N A;  3BIT A;  2BWY A;  3TAV A;  3IU9 A;  2BHB A;  3OOO A;  2G6P A;  5CDV A;  1YW7 A;  3D27 A;  4IPA A;  3L7G A;  2V3X A;  5CDE A;  4OOK A;  1R5G A;  1A16 A;  1W7V A;  2V3Z A;  4ZWP A;  3PEB A;  4ZWU A;  1WBQ A;  2GG3 A;  2MAT A;  1WL9 A;  4MAT A;  2IW2 A;  2GA2 A;  4U75 A;  4IF7 A;  3RVA A;  1XGO A;  1KP0 A;  4ZWO A;  2BWU A;  1KQ9 A;  2P98 A;  2BHC A;  2EVM A;  2GG0 A;  2BHD A;  2GGB A;  1B59 A;  4IU6 A;  2V3Y A;  4PNC A;  4EGE A;  2BN7 A;  4FKC A;  1W2M A;  2GG2 A;  1XGS A;  3FMR A;  2BWV A;  3OVK A;  1QXY A;  5FCF A;  2Q94 A;  4U69 A;  4QR8 A;  3IU8 A;  2BWT A;  2B3K A;  1BOA A;  2GG9 A;  3CB5 A;  2GU6 A;  4S01 A;  4U6E A;  4Z7M A;  2B3L A;  2DFI A;  1JAW A;  4FLK A;  2EVO A;  1PV9 A;  2OAZ A;  3BIQ A;  3MAT A;  4RZY A;  2P99 A;  3S6B A;  2BWS A;  2GU4 A;  1M35 A;  1XGM A;  2Q93 A;  4RZZ A;  4S00 A;  2GG8 A;  5CDL A;  3PKA A;  4PV4 A;  3PKD A;  2EA2 A;  1WY2 A;  3MR1 A;  4RGZ 1;  5FCH A;  4U6Z A;  4FLJ A;  3PN9 A;  2ZSG A;  3FMQ A;  1MAT A;  5JFR A;  2GZ5 A;  5D6E A;  5CLS A;  2OKN A;  4IKR A;  2BHA A;  2EVC A;  1R5H A;  4B28 A;  5CE6 A;  1QXW A;  1C24 A;  3Q6D A;  1XNZ A;  2BWX A;  1KQ0 A;  4U70 A;  3IG4 A;  2NQ6 A;  5D6F A;  1QZY A;  4U1B A;  2GU5 A;  3O5V A;  2ADU A;  4IKT A;  1BN5 A;  1XGN A;  4U76 A;  4KM3 A;  4A6V A;  1QXZ A;  1YW9 A;  4FUK A;  4U73 A;  4FLI A;  1C27 A;  5CNX A;  4FO8 A;  4U6C A;  1B6A A;  3PKE A;  4U71 A;  1WLR A;  3CTZ A;  4A6W A; 
#chains in the Genus database with same CATH topology
 4U6J A;  3BIP A;  2BWW A;  4FO7 A;  2BH3 A;  4S2T P;  1C21 A;  4U6W A;  5JHU A;  1R58 A;  3CB6 A;  2GG7 A;  2Q96 A;  3L24 A;  1YW8 A;  1CHM A;  5E2C A;  3PKC A;  2GTX A;  2Q8K A;  4FLL A;  2Q95 A;  4HXX A;  3IL0 A;  4IEC A;  4ZNG A;  2BB7 A;  4IKS A;  1C23 A;  2GG5 A;  4IDY A;  1YVM A;  5E5B A;  1WN1 A;  2P9A A;  2Q92 A;  3QOC A;  4S2R P;  1C22 A;  1YJ3 A;  2GU7 A;  3ROR A;  4IKU A;  5JI6 A;  2GGC A;  2HOW A;  2NQ7 A;  3PKB A;  1N51 A;  4JUQ A;  1WL6 A;  2B3H A;  4R60 A;  1WKM A;  5CIK A;  1O0X A;  2EA4 A;  2V6C A;  3MX6 A;  3TB5 A;  3FM3 A;  3I7M A;  3IU7 A;  1Y1N A;  3BIT A;  2BWY A;  3TAV A;  3IU9 A;  2BHB A;  3OOO A;  2G6P A;  5CDV A;  1YW7 A;  3D27 A;  4IPA A;  3L7G A;  2V3X A;  5CDE A;  4OOK A;  1R5G A;  1A16 A;  1W7V A;  2V3Z A;  4ZWP A;  3PEB A;  4ZWU A;  1WBQ A;  2GG3 A;  2MAT A;  1WL9 A;  4MAT A;  2IW2 A;  2GA2 A;  4U75 A;  4IF7 A;  3RVA A;  1XGO A;  1KP0 A;  4ZWO A;  2BWU A;  1KQ9 A;  2P98 A;  2BHC A;  2EVM A;  2GG0 A;  2BHD A;  2GGB A;  1B59 A;  4IU6 A;  2V3Y A;  4PNC A;  4EGE A;  2BN7 A;  4FKC A;  1W2M A;  2GG2 A;  1XGS A;  3FMR A;  2BWV A;  3OVK A;  1QXY A;  5FCF A;  2Q94 A;  4U69 A;  4QR8 A;  3IU8 A;  2BWT A;  2B3K A;  1BOA A;  2GG9 A;  3CB5 A;  2GU6 A;  4S01 A;  4U6E A;  4Z7M A;  2B3L A;  2DFI A;  1JAW A;  4FLK A;  2EVO A;  1PV9 A;  2OAZ A;  3BIQ A;  3MAT A;  4RZY A;  2P99 A;  3S6B A;  2BWS A;  2GU4 A;  1M35 A;  1XGM A;  2Q93 A;  4RZZ A;  4S00 A;  2GG8 A;  5CDL A;  3PKA A;  4PV4 A;  3PKD A;  2EA2 A;  1WY2 A;  3MR1 A;  4RGZ 1;  5FCH A;  4U6Z A;  4FLJ A;  3PN9 A;  2ZSG A;  3FMQ A;  1MAT A;  5JFR A;  2GZ5 A;  5D6E A;  5CLS A;  2OKN A;  4IKR A;  2BHA A;  2EVC A;  1R5H A;  4B28 A;  5CE6 A;  1QXW A;  1C24 A;  3Q6D A;  1XNZ A;  2BWX A;  1KQ0 A;  4U70 A;  3IG4 A;  2NQ6 A;  5D6F A;  1QZY A;  4U1B A;  2GU5 A;  3O5V A;  2ADU A;  4IKT A;  1BN5 A;  1XGN A;  4U76 A;  4KM3 A;  4A6V A;  1QXZ A;  1YW9 A;  4FUK A;  4U73 A;  4FLI A;  1C27 A;  5CNX A;  4FO8 A;  4U6C A;  1B6A A;  3PKE A;  4U71 A;  1WLR A;  3CTZ A;  4A6W A; 
#chains in the Genus database with same CATH homology
 4U6J A;  3BIP A;  2BWW A;  4FO7 A;  2BH3 A;  4S2T P;  1C21 A;  4U6W A;  5JHU A;  1R58 A;  3CB6 A;  2GG7 A;  2Q96 A;  3L24 A;  1YW8 A;  1CHM A;  5E2C A;  3PKC A;  2GTX A;  2Q8K A;  4FLL A;  2Q95 A;  4HXX A;  3IL0 A;  4IEC A;  4ZNG A;  2BB7 A;  4IKS A;  1C23 A;  2GG5 A;  4IDY A;  1YVM A;  5E5B A;  1WN1 A;  2P9A A;  2Q92 A;  3QOC A;  4S2R P;  1C22 A;  1YJ3 A;  2GU7 A;  3ROR A;  4IKU A;  5JI6 A;  2GGC A;  2HOW A;  2NQ7 A;  3PKB A;  1N51 A;  4JUQ A;  1WL6 A;  2B3H A;  4R60 A;  1WKM A;  5CIK A;  1O0X A;  2EA4 A;  2V6C A;  3MX6 A;  3TB5 A;  3FM3 A;  3I7M A;  3IU7 A;  1Y1N A;  3BIT A;  2BWY A;  3TAV A;  3IU9 A;  2BHB A;  3OOO A;  2G6P A;  5CDV A;  1YW7 A;  3D27 A;  4IPA A;  3L7G A;  2V3X A;  5CDE A;  4OOK A;  1R5G A;  1A16 A;  1W7V A;  2V3Z A;  4ZWP A;  3PEB A;  4ZWU A;  1WBQ A;  2GG3 A;  2MAT A;  1WL9 A;  4MAT A;  2IW2 A;  2GA2 A;  4U75 A;  4IF7 A;  3RVA A;  1XGO A;  1KP0 A;  4ZWO A;  2BWU A;  1KQ9 A;  2P98 A;  2BHC A;  2EVM A;  2GG0 A;  2BHD A;  2GGB A;  1B59 A;  4IU6 A;  2V3Y A;  4PNC A;  4EGE A;  2BN7 A;  4FKC A;  1W2M A;  2GG2 A;  1XGS A;  3FMR A;  2BWV A;  3OVK A;  1QXY A;  5FCF A;  2Q94 A;  4U69 A;  4QR8 A;  3IU8 A;  2BWT A;  2B3K A;  1BOA A;  2GG9 A;  3CB5 A;  2GU6 A;  4S01 A;  4U6E A;  4Z7M A;  2B3L A;  2DFI A;  1JAW A;  4FLK A;  2EVO A;  1PV9 A;  2OAZ A;  3BIQ A;  3MAT A;  4RZY A;  2P99 A;  3S6B A;  2BWS A;  2GU4 A;  1M35 A;  1XGM A;  2Q93 A;  4RZZ A;  4S00 A;  2GG8 A;  5CDL A;  3PKA A;  4PV4 A;  3PKD A;  2EA2 A;  1WY2 A;  3MR1 A;  4RGZ 1;  5FCH A;  4U6Z A;  4FLJ A;  3PN9 A;  2ZSG A;  3FMQ A;  1MAT A;  5JFR A;  2GZ5 A;  5D6E A;  5CLS A;  2OKN A;  4IKR A;  2BHA A;  2EVC A;  1R5H A;  4B28 A;  5CE6 A;  1QXW A;  1C24 A;  3Q6D A;  1XNZ A;  2BWX A;  1KQ0 A;  4U70 A;  3IG4 A;  2NQ6 A;  5D6F A;  1QZY A;  4U1B A;  2GU5 A;  3O5V A;  2ADU A;  4IKT A;  1BN5 A;  1XGN A;  4U76 A;  4KM3 A;  4A6V A;  1QXZ A;  1YW9 A;  4FUK A;  4U73 A;  4FLI A;  1C27 A;  5CNX A;  4FO8 A;  4U6C A;  1B6A A;  3PKE A;  4U71 A;  1WLR A;  3CTZ A;  4A6W A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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