5FCFA

Crystal structure of xaa-pro dipeptidase from xanthomonas campestris, phosphate and mn bound
Total Genus 136
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
136
sequence length
397
structure length
397
Chain Sequence
TQIGGMSLDQARTQLAPWTQRAAPIGADEYQQRIERARVLMRAQGVDALLIGAGTSLRYFSGVPWGASERLVALLLTTEGDPVLICPAFEEGSLDAVLQLPVRKRLWEEHEDPYALVVQAMDEQHAHALALDPGIAFAVHTGLRAHLGTAIRDAGAIIDGCRMCKSPAELALMQQACDMTLLVQRLAAGIAHEGIGTDQLVRFIDEAHRALGADNGSTFCIVQFGHATAFPHGIPGVQHLRAGELVLIDTGCTVQGYHSDITRTWIYGTPSDAQQRIWELELAAQAAAFAAVRPGVACEAVDQAARAVLQAAGLGPDYRLPGLPHRTGHGCGLAIHEAPYLVRGNRQPLQPGMCASNEPMIVVPGAFGVRLEDHFYVTDTGAQWFTPPSVAIDQPFA
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
molecule keywords Proline dipeptidase
publication title Crystal structure and biochemical investigations reveal novel mode of substrate selectivity and illuminate substrate inhibition and allostericity in a subfamily of Xaa-Pro dipeptidases.
pubmed doi rcsb
source organism Xanthomonas campestris pv. campestris str. atcc 33913
molecule tags Hydrolase
total genus 136
structure length 397
sequence length 397
chains with identical sequence B
ec nomenclature ec 3.4.13.9: Xaa-Pro dipeptidase.
pdb deposition date 2015-12-15

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
A PF01321 Creatinase_N Creatinase/Prolidase N-terminal domain
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.40.350.10 Alpha Beta 3-Layer(aba) Sandwich Creatine Amidinohydrolase; Chain A, domain 1 Creatinase/prolidase N-terminal domain 5fcfA01
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 5fcfA02
4U75A 4QR8A 2V3XA 1WKMA 2EVOA 2GU6A 1R5HA 1XGMA 2GA2A 2B3LA 2GGCA 2Q95A 3PKCA 4ZWOA 1YW8A 4IKUA 3BIPA 4IKSA 3PKDA 2GTXA 2NQ7A 4HXXA 4R60A 3QOCA 1XGNA 4MATA 2MATA 3PEBA 3IU9A 3OOOA 4FO8A 2BWWA 2BB7A 5FCFA 2Q93A 3I7MA 4FO7A 1YJ3A 3PN9A 2B3HA 4S00A 3CB5A 1YW7A 1BOAA 1XNZA 2EVMA 2P98A 3IL0A 3BITA 1XGOA 1CHMA 1YVMA 4FLLA 1YW9A 4U1BA 1KQ9A 2GG3A 1JAWA 3FM3A 3IU7A 2BHDA 2Q96A 2G6PA 4U6CA 2GGBA 2GG8A 2BWUA 4B28A 2BWXA 1WN1A 2BHCA 5CDVA 5E2CA 1C22A 2GG7A 2GU5A 4JUQA 3OVKA 1KP0A 4ZNGA 1B59A 4RGZ1 4IKRA 2GG0A 4A6VA 1QXZA 4IPAA 4IKTA 3FMQA 4U6WA 3L24A 3PKBA 4Z7MA 1W2MA 1QXYA 5CIKA 4U69A 1B6AA 5JHUA 5JI6A 2ADUA 5CE6A 1PV9A 5E5BA 2IW2A 4EGEA 4U76A 5JFRA 4S2RP 2V6CA 2Q8KA 3S6BA 2BHAA 4IF7A 2EA4A 1WLRA 1R58A 2BWSA 5D6FA 4U6ZA 3L7GA 3TB5A 2Q94A 3PKEA 2V3ZA 4PV4A 4ZWUA 2V3YA 2EVCA 2Q92A 1C27A 3RORA 4S01A 3CB6A 2ZSGA 1O0XA 2BN7A 2BH3A 1C23A 4FLIA 4U6EA 2GZ5A 4FLKA 1WL9A 4RZZA 2GG5A 3Q6DA 4U6JA 1M35A 2GG2A 5CNXA 3IG4A 4U70A 2BWTA 5CDEA 2NQ6A 2BWVA 4FUKA 5CLSA 1R5GA 1W7VA 4OOKA 1Y1NA 3MX6A 3O5VA 3IU8A 1BN5A 2GU7A 1N51A 2GG9A 5FCHA 1C21A 4PNCA 3FMRA 4U71A 4IECA 1WY2A 2OKNA 2BHBA 4IDYA 1WBQA 3RVAA 2OAZA 2EA2A 4IU6A 1A16A 3BIQA 2P9AA 3D27A 3TAVA 4FLJA 4ZWPA 4U73A 1KQ0A 1QXWA 1WL6A 4S2TP 5CDLA 3MATA 1XGSA 3MR1A 4RZYA 2B3KA 3PKAA 1MATA 2GU4A 2P99A 1QZYA 3CTZA 4FKCA 2HOWA 4KM3A 4A6WA 1C24A 2DFIA 5D6EA 2BWYA
chains in the Genus database with same CATH superfamily
4U75A 4QR8A 2V3XA 1WKMA 2EVOA 2GU6A 1R5HA 1XGMA 2GA2A 2B3LA 2GGCA 2Q95A 3PKCA 4ZWOA 1YW8A 4IKUA 3BIPA 4IKSA 3PKDA 2GTXA 2NQ7A 4HXXA 4R60A 3QOCA 1XGNA 4MATA 2MATA 3PEBA 3IU9A 3OOOA 4FO8A 2BWWA 2BB7A 5FCFA 2Q93A 3I7MA 4FO7A 1YJ3A 3PN9A 2B3HA 4S00A 3CB5A 1YW7A 1BOAA 1XNZA 2EVMA 2P98A 3IL0A 3BITA 1XGOA 1CHMA 1YVMA 4FLLA 1YW9A 4U1BA 1KQ9A 2GG3A 1JAWA 3FM3A 3IU7A 2BHDA 2Q96A 2G6PA 4U6CA 2GGBA 2GG8A 2BWUA 4B28A 2BWXA 1WN1A 2BHCA 5CDVA 5E2CA 1C22A 2GG7A 2GU5A 4JUQA 3OVKA 1KP0A 4ZNGA 1B59A 4RGZ1 4IKRA 2GG0A 4A6VA 1QXZA 4IPAA 4IKTA 3FMQA 4U6WA 3L24A 3PKBA 4Z7MA 1W2MA 1QXYA 5CIKA 4U69A 1B6AA 5JHUA 5JI6A 2ADUA 5CE6A 1PV9A 5E5BA 2IW2A 4EGEA 4U76A 5JFRA 4S2RP 2V6CA 2Q8KA 3S6BA 2BHAA 4IF7A 2EA4A 1WLRA 1R58A 2BWSA 5D6FA 4U6ZA 3L7GA 3TB5A 2Q94A 3PKEA 2V3ZA 4PV4A 4ZWUA 2V3YA 2EVCA 2Q92A 1C27A 3RORA 4S01A 3CB6A 2ZSGA 1O0XA 2BN7A 2BH3A 1C23A 4FLIA 4U6EA 2GZ5A 4FLKA 1WL9A 4RZZA 2GG5A 3Q6DA 4U6JA 1M35A 2GG2A 5CNXA 3IG4A 4U70A 2BWTA 5CDEA 2NQ6A 2BWVA 4FUKA 5CLSA 1R5GA 1W7VA 4OOKA 1Y1NA 3MX6A 3O5VA 3IU8A 1BN5A 2GU7A 1N51A 2GG9A 5FCHA 1C21A 4PNCA 3FMRA 4U71A 4IECA 1WY2A 2OKNA 2BHBA 4IDYA 1WBQA 3RVAA 2OAZA 2EA2A 4IU6A 1A16A 3BIQA 2P9AA 3D27A 3TAVA 4FLJA 4ZWPA 4U73A 1KQ0A 1QXWA 1WL6A 4S2TP 5CDLA 3MATA 1XGSA 3MR1A 4RZYA 2B3KA 3PKAA 1MATA 2GU4A 2P99A 1QZYA 3CTZA 4FKCA 2HOWA 4KM3A 4A6WA 1C24A 2DFIA 5D6EA 2BWYA
chains in the Genus database with same CATH topology
4U75A 4QR8A 2V3XA 1WKMA 2EVOA 2GU6A 1R5HA 1XGMA 2GA2A 2B3LA 2GGCA 2Q95A 3PKCA 4ZWOA 1YW8A 4IKUA 3BIPA 4IKSA 3PKDA 2GTXA 2NQ7A 4HXXA 4R60A 3QOCA 1XGNA 4MATA 2MATA 3PEBA 3IU9A 3OOOA 4FO8A 2BWWA 2BB7A 5FCFA 2Q93A 3I7MA 4FO7A 1YJ3A 3PN9A 2B3HA 4S00A 3CB5A 1YW7A 1BOAA 1XNZA 2EVMA 2P98A 3IL0A 3BITA 1XGOA 1CHMA 1YVMA 4FLLA 1YW9A 4U1BA 1KQ9A 2GG3A 1JAWA 3FM3A 3IU7A 2BHDA 2Q96A 2G6PA 4U6CA 2GGBA 2GG8A 2BWUA 4B28A 2BWXA 1WN1A 2BHCA 5CDVA 5E2CA 1C22A 2GG7A 2GU5A 4JUQA 3OVKA 1KP0A 4ZNGA 1B59A 4RGZ1 4IKRA 2GG0A 4A6VA 1QXZA 4IPAA 4IKTA 3FMQA 4U6WA 3L24A 3PKBA 4Z7MA 1W2MA 1QXYA 5CIKA 4U69A 1B6AA 5JHUA 5JI6A 2ADUA 5CE6A 1PV9A 5E5BA 2IW2A 4EGEA 4U76A 5JFRA 4S2RP 2V6CA 2Q8KA 3S6BA 2BHAA 4IF7A 2EA4A 1WLRA 1R58A 2BWSA 5D6FA 4U6ZA 3L7GA 3TB5A 2Q94A 3PKEA 2V3ZA 4PV4A 4ZWUA 2V3YA 2EVCA 2Q92A 1C27A 3RORA 4S01A 3CB6A 2ZSGA 1O0XA 2BN7A 2BH3A 1C23A 4FLIA 4U6EA 2GZ5A 4FLKA 1WL9A 4RZZA 2GG5A 3Q6DA 4U6JA 1M35A 2GG2A 5CNXA 3IG4A 4U70A 2BWTA 5CDEA 2NQ6A 2BWVA 4FUKA 5CLSA 1R5GA 1W7VA 4OOKA 1Y1NA 3MX6A 3O5VA 3IU8A 1BN5A 2GU7A 1N51A 2GG9A 5FCHA 1C21A 4PNCA 3FMRA 4U71A 4IECA 1WY2A 2OKNA 2BHBA 4IDYA 1WBQA 3RVAA 2OAZA 2EA2A 4IU6A 1A16A 3BIQA 2P9AA 3D27A 3TAVA 4FLJA 4ZWPA 4U73A 1KQ0A 1QXWA 1WL6A 4S2TP 5CDLA 3MATA 1XGSA 3MR1A 4RZYA 2B3KA 3PKAA 1MATA 2GU4A 2P99A 1QZYA 3CTZA 4FKCA 2HOWA 4KM3A 4A6WA 1C24A 2DFIA 5D6EA 2BWYA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4U75 A;  4QR8 A;  2V3X A;  1WKM A;  2EVO A;  2GU6 A;  1R5H A;  1XGM A;  2GA2 A;  2B3L A;  2GGC A;  2Q95 A;  3PKC A;  4ZWO A;  1YW8 A;  4IKU A;  3BIP A;  4IKS A;  3PKD A;  2GTX A;  2NQ7 A;  4HXX A;  4R60 A;  3QOC A;  1XGN A;  4MAT A;  2MAT A;  3PEB A;  3IU9 A;  3OOO A;  4FO8 A;  2BWW A;  2BB7 A;  5FCF A;  2Q93 A;  3I7M A;  4FO7 A;  1YJ3 A;  3PN9 A;  2B3H A;  4S00 A;  3CB5 A;  1YW7 A;  1BOA A;  1XNZ A;  2EVM A;  2P98 A;  3IL0 A;  3BIT A;  1XGO A;  1CHM A;  1YVM A;  4FLL A;  1YW9 A;  4U1B A;  1KQ9 A;  2GG3 A;  1JAW A;  3FM3 A;  3IU7 A;  2BHD A;  2Q96 A;  2G6P A;  4U6C A;  2GGB A;  2GG8 A;  2BWU A;  4B28 A;  2BWX A;  1WN1 A;  2BHC A;  5CDV A;  5E2C A;  1C22 A;  2GG7 A;  2GU5 A;  4JUQ A;  3OVK A;  1KP0 A;  4ZNG A;  1B59 A;  4RGZ 1;  4IKR A;  2GG0 A;  4A6V A;  1QXZ A;  4IPA A;  4IKT A;  3FMQ A;  4U6W A;  3L24 A;  3PKB A;  4Z7M A;  1W2M A;  1QXY A;  5CIK A;  4U69 A;  1B6A A;  5JHU A;  5JI6 A;  2ADU A;  5CE6 A;  1PV9 A;  5E5B A;  2IW2 A;  4EGE A;  4U76 A;  5JFR A;  4S2R P;  2V6C A;  2Q8K A;  3S6B A;  2BHA A;  4IF7 A;  2EA4 A;  1WLR A;  1R58 A;  2BWS A;  5D6F A;  4U6Z A;  3L7G A;  3TB5 A;  2Q94 A;  3PKE A;  2V3Z A;  4PV4 A;  4ZWU A;  2V3Y A;  2EVC A;  2Q92 A;  1C27 A;  3ROR A;  4S01 A;  3CB6 A;  2ZSG A;  1O0X A;  2BN7 A;  2BH3 A;  1C23 A;  4FLI A;  4U6E A;  2GZ5 A;  4FLK A;  1WL9 A;  4RZZ A;  2GG5 A;  3Q6D A;  4U6J A;  1M35 A;  2GG2 A;  5CNX A;  3IG4 A;  4U70 A;  2BWT A;  5CDE A;  2NQ6 A;  2BWV A;  4FUK A;  5CLS A;  1R5G A;  1W7V A;  4OOK A;  1Y1N A;  3MX6 A;  3O5V A;  3IU8 A;  1BN5 A;  2GU7 A;  1N51 A;  2GG9 A;  5FCH A;  1C21 A;  4PNC A;  3FMR A;  4U71 A;  4IEC A;  1WY2 A;  2OKN A;  2BHB A;  4IDY A;  1WBQ A;  3RVA A;  2OAZ A;  2EA2 A;  4IU6 A;  1A16 A;  3BIQ A;  2P9A A;  3D27 A;  3TAV A;  4FLJ A;  4ZWP A;  4U73 A;  1KQ0 A;  1QXW A;  1WL6 A;  4S2T P;  5CDL A;  3MAT A;  1XGS A;  3MR1 A;  4RZY A;  2B3K A;  3PKA A;  1MAT A;  2GU4 A;  2P99 A;  1QZY A;  3CTZ A;  4FKC A;  2HOW A;  4KM3 A;  4A6W A;  1C24 A;  2DFI A;  5D6E A;  2BWY A; 
#chains in the Genus database with same CATH topology
 4U75 A;  4QR8 A;  2V3X A;  1WKM A;  2EVO A;  2GU6 A;  1R5H A;  1XGM A;  2GA2 A;  2B3L A;  2GGC A;  2Q95 A;  3PKC A;  4ZWO A;  1YW8 A;  4IKU A;  3BIP A;  4IKS A;  3PKD A;  2GTX A;  2NQ7 A;  4HXX A;  4R60 A;  3QOC A;  1XGN A;  4MAT A;  2MAT A;  3PEB A;  3IU9 A;  3OOO A;  4FO8 A;  2BWW A;  2BB7 A;  5FCF A;  2Q93 A;  3I7M A;  4FO7 A;  1YJ3 A;  3PN9 A;  2B3H A;  4S00 A;  3CB5 A;  1YW7 A;  1BOA A;  1XNZ A;  2EVM A;  2P98 A;  3IL0 A;  3BIT A;  1XGO A;  1CHM A;  1YVM A;  4FLL A;  1YW9 A;  4U1B A;  1KQ9 A;  2GG3 A;  1JAW A;  3FM3 A;  3IU7 A;  2BHD A;  2Q96 A;  2G6P A;  4U6C A;  2GGB A;  2GG8 A;  2BWU A;  4B28 A;  2BWX A;  1WN1 A;  2BHC A;  5CDV A;  5E2C A;  1C22 A;  2GG7 A;  2GU5 A;  4JUQ A;  3OVK A;  1KP0 A;  4ZNG A;  1B59 A;  4RGZ 1;  4IKR A;  2GG0 A;  4A6V A;  1QXZ A;  4IPA A;  4IKT A;  3FMQ A;  4U6W A;  3L24 A;  3PKB A;  4Z7M A;  1W2M A;  1QXY A;  5CIK A;  4U69 A;  1B6A A;  5JHU A;  5JI6 A;  2ADU A;  5CE6 A;  1PV9 A;  5E5B A;  2IW2 A;  4EGE A;  4U76 A;  5JFR A;  4S2R P;  2V6C A;  2Q8K A;  3S6B A;  2BHA A;  4IF7 A;  2EA4 A;  1WLR A;  1R58 A;  2BWS A;  5D6F A;  4U6Z A;  3L7G A;  3TB5 A;  2Q94 A;  3PKE A;  2V3Z A;  4PV4 A;  4ZWU A;  2V3Y A;  2EVC A;  2Q92 A;  1C27 A;  3ROR A;  4S01 A;  3CB6 A;  2ZSG A;  1O0X A;  2BN7 A;  2BH3 A;  1C23 A;  4FLI A;  4U6E A;  2GZ5 A;  4FLK A;  1WL9 A;  4RZZ A;  2GG5 A;  3Q6D A;  4U6J A;  1M35 A;  2GG2 A;  5CNX A;  3IG4 A;  4U70 A;  2BWT A;  5CDE A;  2NQ6 A;  2BWV A;  4FUK A;  5CLS A;  1R5G A;  1W7V A;  4OOK A;  1Y1N A;  3MX6 A;  3O5V A;  3IU8 A;  1BN5 A;  2GU7 A;  1N51 A;  2GG9 A;  5FCH A;  1C21 A;  4PNC A;  3FMR A;  4U71 A;  4IEC A;  1WY2 A;  2OKN A;  2BHB A;  4IDY A;  1WBQ A;  3RVA A;  2OAZ A;  2EA2 A;  4IU6 A;  1A16 A;  3BIQ A;  2P9A A;  3D27 A;  3TAV A;  4FLJ A;  4ZWP A;  4U73 A;  1KQ0 A;  1QXW A;  1WL6 A;  4S2T P;  5CDL A;  3MAT A;  1XGS A;  3MR1 A;  4RZY A;  2B3K A;  3PKA A;  1MAT A;  2GU4 A;  2P99 A;  1QZY A;  3CTZ A;  4FKC A;  2HOW A;  4KM3 A;  4A6W A;  1C24 A;  2DFI A;  5D6E A;  2BWY A; 
#chains in the Genus database with same CATH homology
 4U75 A;  4QR8 A;  2V3X A;  1WKM A;  2EVO A;  2GU6 A;  1R5H A;  1XGM A;  2GA2 A;  2B3L A;  2GGC A;  2Q95 A;  3PKC A;  4ZWO A;  1YW8 A;  4IKU A;  3BIP A;  4IKS A;  3PKD A;  2GTX A;  2NQ7 A;  4HXX A;  4R60 A;  3QOC A;  1XGN A;  4MAT A;  2MAT A;  3PEB A;  3IU9 A;  3OOO A;  4FO8 A;  2BWW A;  2BB7 A;  5FCF A;  2Q93 A;  3I7M A;  4FO7 A;  1YJ3 A;  3PN9 A;  2B3H A;  4S00 A;  3CB5 A;  1YW7 A;  1BOA A;  1XNZ A;  2EVM A;  2P98 A;  3IL0 A;  3BIT A;  1XGO A;  1CHM A;  1YVM A;  4FLL A;  1YW9 A;  4U1B A;  1KQ9 A;  2GG3 A;  1JAW A;  3FM3 A;  3IU7 A;  2BHD A;  2Q96 A;  2G6P A;  4U6C A;  2GGB A;  2GG8 A;  2BWU A;  4B28 A;  2BWX A;  1WN1 A;  2BHC A;  5CDV A;  5E2C A;  1C22 A;  2GG7 A;  2GU5 A;  4JUQ A;  3OVK A;  1KP0 A;  4ZNG A;  1B59 A;  4RGZ 1;  4IKR A;  2GG0 A;  4A6V A;  1QXZ A;  4IPA A;  4IKT A;  3FMQ A;  4U6W A;  3L24 A;  3PKB A;  4Z7M A;  1W2M A;  1QXY A;  5CIK A;  4U69 A;  1B6A A;  5JHU A;  5JI6 A;  2ADU A;  5CE6 A;  1PV9 A;  5E5B A;  2IW2 A;  4EGE A;  4U76 A;  5JFR A;  4S2R P;  2V6C A;  2Q8K A;  3S6B A;  2BHA A;  4IF7 A;  2EA4 A;  1WLR A;  1R58 A;  2BWS A;  5D6F A;  4U6Z A;  3L7G A;  3TB5 A;  2Q94 A;  3PKE A;  2V3Z A;  4PV4 A;  4ZWU A;  2V3Y A;  2EVC A;  2Q92 A;  1C27 A;  3ROR A;  4S01 A;  3CB6 A;  2ZSG A;  1O0X A;  2BN7 A;  2BH3 A;  1C23 A;  4FLI A;  4U6E A;  2GZ5 A;  4FLK A;  1WL9 A;  4RZZ A;  2GG5 A;  3Q6D A;  4U6J A;  1M35 A;  2GG2 A;  5CNX A;  3IG4 A;  4U70 A;  2BWT A;  5CDE A;  2NQ6 A;  2BWV A;  4FUK A;  5CLS A;  1R5G A;  1W7V A;  4OOK A;  1Y1N A;  3MX6 A;  3O5V A;  3IU8 A;  1BN5 A;  2GU7 A;  1N51 A;  2GG9 A;  5FCH A;  1C21 A;  4PNC A;  3FMR A;  4U71 A;  4IEC A;  1WY2 A;  2OKN A;  2BHB A;  4IDY A;  1WBQ A;  3RVA A;  2OAZ A;  2EA2 A;  4IU6 A;  1A16 A;  3BIQ A;  2P9A A;  3D27 A;  3TAV A;  4FLJ A;  4ZWP A;  4U73 A;  1KQ0 A;  1QXW A;  1WL6 A;  4S2T P;  5CDL A;  3MAT A;  1XGS A;  3MR1 A;  4RZY A;  2B3K A;  3PKA A;  1MAT A;  2GU4 A;  2P99 A;  1QZY A;  3CTZ A;  4FKC A;  2HOW A;  4KM3 A;  4A6W A;  1C24 A;  2DFI A;  5D6E A;  2BWY A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...