1MATA

Structure of the cobalt-dependent methionine aminopeptidase from escherichia coli: a new type of proteolytic enzyme
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
263
structure length
263
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme.
pubmed doi rcsb
molecule tags Hydrolase(alpha-aminoacylpeptide)
source organism Escherichia coli
molecule keywords METHIONYL AMINOPEPTIDASE
total genus 77
structure length 263
sequence length 263
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1992-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1matA00
4FO8A 2OAZA 4JUQA 4IU6A 4PV4A 2G6PA 4RZZA 1C22A 2BWYA 2NQ6A 4FUKA 3RVAA 2V3YA 2V3ZA 1B6AA 2B3LA 4EGEA 4IKSA 3Q6DA 4U69A 2EVCA 1W7VA 1BN5A 1QXYA 2EA4A 4U6WA 2GU5A 2GU7A 4U71A 4IPAA 4HXXA 1YJ3A 2Q92A 3PKEA 4RZYA 1W2MA 2GU4A 5FCFA 2GG5A 2GG0A 1R5HA 4IF7A 1XGOA 2DFIA 1R58A 2BHAA 3S6BA 1XGMA 2Q8KA 2EVOA 2ZSGA 4FLIA 5D6FA 1B59A 2BWSA 1C21A 3IU8A 5JFRA 4U6JA 4U6ZA 2Q93A 3FMQA 1BOAA 1XNZA 1WKMA 2BWXA 3PKAA 3PKCA 3RORA 2GG8A 4IKTA 4IKRA 5CDEA 1N51A 2P9AA 1C24A 2BHCA 2BWWA 3L24A 2HOWA 5FCHA 1YVMA 5CDLA 2Q94A 4S2TP 5E5BA 2BWVA 1QZYA 1QXZA 2GTXA 1PV9A 2B3KA 1YW7A 3BIPA 3MR1A 5CNXA 4U6EA 2GU6A 2GGBA 3BITA 1JAWA 1WL9A 4U76A 2BN7A 1MATA 2P98A 4FLKA 2GG7A 4MATA 4QR8A 1A16A 2BHDA 3PKBA 3TB5A 5JHUA 2GG3A 3IG4A 4FLJA 1KQ9A 3CB6A 4FKCA 1WN1A 3D27A 4IKUA 2V6CA 2OKNA 4ZWUA 1WY2A 1CHMA 1QXWA 4A6WA 2IW2A 2BH3A 2MATA 2B3HA 1YW8A 4FLLA 4U73A 3IU7A 4U1BA 4FO7A 4U70A 2BHBA 3CB5A 4ZNGA 2BB7A 4IECA 4S00A 1WLRA 4S2RP 5CDVA 1YW9A 4KM3A 4U6CA 2GA2A 2GG2A 1R5GA 4Z7MA 4B28A 3CTZA 1C27A 4IDYA 3FMRA 4S01A 4PNCA 3L7GA 2ADUA 3PKDA 5CE6A 2BWTA 1C23A 3BIQA 3TAVA 2GGCA 3MATA 4A6VA 5CLSA 1WL6A 5JI6A 1KQ0A 2BWUA 4U75A 2P99A 1O0XA 2EA2A 1Y1NA 4OOKA 4ZWOA 4ZWPA 2NQ7A 1KP0A 2EVMA 2Q96A 5CIKA 3FM3A 2V3XA 5D6EA 1M35A 2GZ5A 2Q95A 4R60A 1XGNA 1XGSA 2GG9A 4RGZ1 3MX6A 3IU9A 1WBQA
chains in the Genus database with same CATH superfamily
4FO8A 2OAZA 4JUQA 4IU6A 4PV4A 2G6PA 4RZZA 1C22A 2BWYA 2NQ6A 4FUKA 3RVAA 2V3YA 2V3ZA 1B6AA 2B3LA 4EGEA 4IKSA 3Q6DA 4U69A 2EVCA 1W7VA 1BN5A 1QXYA 2EA4A 4U6WA 2GU5A 2GU7A 4U71A 4IPAA 4HXXA 1YJ3A 2Q92A 3PKEA 4RZYA 1W2MA 2GU4A 5FCFA 2GG5A 2GG0A 1R5HA 4IF7A 1XGOA 2DFIA 1R58A 2BHAA 3S6BA 1XGMA 2Q8KA 2EVOA 2ZSGA 4FLIA 5D6FA 1B59A 2BWSA 1C21A 3IU8A 5JFRA 4U6JA 4U6ZA 2Q93A 3FMQA 1BOAA 1XNZA 1WKMA 2BWXA 3PKAA 3PKCA 3RORA 2GG8A 4IKTA 4IKRA 5CDEA 1N51A 2P9AA 1C24A 2BHCA 2BWWA 3L24A 2HOWA 5FCHA 1YVMA 5CDLA 2Q94A 4S2TP 5E5BA 2BWVA 1QZYA 1QXZA 2GTXA 1PV9A 2B3KA 1YW7A 3BIPA 3MR1A 5CNXA 4U6EA 2GU6A 2GGBA 3BITA 1JAWA 1WL9A 4U76A 2BN7A 1MATA 2P98A 4FLKA 2GG7A 4MATA 4QR8A 1A16A 2BHDA 3PKBA 3TB5A 5JHUA 2GG3A 3IG4A 4FLJA 1KQ9A 3CB6A 4FKCA 1WN1A 3D27A 4IKUA 2V6CA 2OKNA 4ZWUA 1WY2A 1CHMA 1QXWA 4A6WA 2IW2A 2BH3A 2MATA 2B3HA 1YW8A 4FLLA 4U73A 3IU7A 4U1BA 4FO7A 4U70A 2BHBA 3CB5A 4ZNGA 2BB7A 4IECA 4S00A 1WLRA 4S2RP 5CDVA 1YW9A 4KM3A 4U6CA 2GA2A 2GG2A 1R5GA 4Z7MA 4B28A 3CTZA 1C27A 4IDYA 3FMRA 4S01A 4PNCA 3L7GA 2ADUA 3PKDA 5CE6A 2BWTA 1C23A 3BIQA 3TAVA 2GGCA 3MATA 4A6VA 5CLSA 1WL6A 5JI6A 1KQ0A 2BWUA 4U75A 2P99A 1O0XA 2EA2A 1Y1NA 4OOKA 4ZWOA 4ZWPA 2NQ7A 1KP0A 2EVMA 2Q96A 5CIKA 3FM3A 2V3XA 5D6EA 1M35A 2GZ5A 2Q95A 4R60A 1XGNA 1XGSA 2GG9A 4RGZ1 3MX6A 3IU9A 1WBQA
chains in the Genus database with same CATH topology
4FO8A 2OAZA 4JUQA 4IU6A 4PV4A 2G6PA 4RZZA 1C22A 2BWYA 2NQ6A 4FUKA 3RVAA 2V3YA 2V3ZA 1B6AA 2B3LA 4EGEA 4IKSA 3Q6DA 4U69A 2EVCA 1W7VA 1BN5A 1QXYA 2EA4A 4U6WA 2GU5A 2GU7A 4U71A 4IPAA 4HXXA 1YJ3A 2Q92A 3PKEA 4RZYA 1W2MA 2GU4A 5FCFA 2GG5A 2GG0A 1R5HA 4IF7A 1XGOA 2DFIA 1R58A 2BHAA 3S6BA 1XGMA 2Q8KA 2EVOA 2ZSGA 4FLIA 5D6FA 1B59A 2BWSA 1C21A 3IU8A 5JFRA 4U6JA 4U6ZA 2Q93A 3FMQA 1BOAA 1XNZA 1WKMA 2BWXA 3PKAA 3PKCA 3RORA 2GG8A 4IKTA 4IKRA 5CDEA 1N51A 2P9AA 1C24A 2BHCA 2BWWA 3L24A 2HOWA 5FCHA 1YVMA 5CDLA 2Q94A 4S2TP 5E5BA 2BWVA 1QZYA 1QXZA 2GTXA 1PV9A 2B3KA 1YW7A 3BIPA 3MR1A 5CNXA 4U6EA 2GU6A 2GGBA 3BITA 1JAWA 1WL9A 4U76A 2BN7A 1MATA 2P98A 4FLKA 2GG7A 4MATA 4QR8A 1A16A 2BHDA 3PKBA 3TB5A 5JHUA 2GG3A 3IG4A 4FLJA 1KQ9A 3CB6A 4FKCA 1WN1A 3D27A 4IKUA 2V6CA 2OKNA 4ZWUA 1WY2A 1CHMA 1QXWA 4A6WA 2IW2A 2BH3A 2MATA 2B3HA 1YW8A 4FLLA 4U73A 3IU7A 4U1BA 4FO7A 4U70A 2BHBA 3CB5A 4ZNGA 2BB7A 4IECA 4S00A 1WLRA 4S2RP 5CDVA 1YW9A 4KM3A 4U6CA 2GA2A 2GG2A 1R5GA 4Z7MA 4B28A 3CTZA 1C27A 4IDYA 3FMRA 4S01A 4PNCA 3L7GA 2ADUA 3PKDA 5CE6A 2BWTA 1C23A 3BIQA 3TAVA 2GGCA 3MATA 4A6VA 5CLSA 1WL6A 5JI6A 1KQ0A 2BWUA 4U75A 2P99A 1O0XA 2EA2A 1Y1NA 4OOKA 4ZWOA 4ZWPA 2NQ7A 1KP0A 2EVMA 2Q96A 5CIKA 3FM3A 2V3XA 5D6EA 1M35A 2GZ5A 2Q95A 4R60A 1XGNA 1XGSA 2GG9A 4RGZ1 3MX6A 3IU9A 1WBQA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 4FO8 A;  2OAZ A;  4JUQ A;  4IU6 A;  4PV4 A;  2G6P A;  4RZZ A;  1C22 A;  2BWY A;  2NQ6 A;  4FUK A;  3RVA A;  2V3Y A;  2V3Z A;  1B6A A;  2B3L A;  4EGE A;  4IKS A;  3Q6D A;  4U69 A;  2EVC A;  1W7V A;  1BN5 A;  1QXY A;  2EA4 A;  4U6W A;  2GU5 A;  2GU7 A;  4U71 A;  4IPA A;  4HXX A;  1YJ3 A;  2Q92 A;  3PKE A;  4RZY A;  1W2M A;  2GU4 A;  5FCF A;  2GG5 A;  2GG0 A;  1R5H A;  4IF7 A;  1XGO A;  2DFI A;  1R58 A;  2BHA A;  3S6B A;  1XGM A;  2Q8K A;  2EVO A;  2ZSG A;  4FLI A;  5D6F A;  1B59 A;  2BWS A;  1C21 A;  3IU8 A;  5JFR A;  4U6J A;  4U6Z A;  2Q93 A;  3FMQ A;  1BOA A;  1XNZ A;  1WKM A;  2BWX A;  3PKA A;  3PKC A;  3ROR A;  2GG8 A;  4IKT A;  4IKR A;  5CDE A;  1N51 A;  2P9A A;  1C24 A;  2BHC A;  2BWW A;  3L24 A;  2HOW A;  5FCH A;  1YVM A;  5CDL A;  2Q94 A;  4S2T P;  5E5B A;  2BWV A;  1QZY A;  1QXZ A;  2GTX A;  1PV9 A;  2B3K A;  1YW7 A;  3BIP A;  3MR1 A;  5CNX A;  4U6E A;  2GU6 A;  2GGB A;  3BIT A;  1JAW A;  1WL9 A;  4U76 A;  2BN7 A;  1MAT A;  2P98 A;  4FLK A;  2GG7 A;  4MAT A;  4QR8 A;  1A16 A;  2BHD A;  3PKB A;  3TB5 A;  5JHU A;  2GG3 A;  3IG4 A;  4FLJ A;  1KQ9 A;  3CB6 A;  4FKC A;  1WN1 A;  3D27 A;  4IKU A;  2V6C A;  2OKN A;  4ZWU A;  1WY2 A;  1CHM A;  1QXW A;  4A6W A;  2IW2 A;  2BH3 A;  2MAT A;  2B3H A;  1YW8 A;  4FLL A;  4U73 A;  3IU7 A;  4U1B A;  4FO7 A;  4U70 A;  2BHB A;  3CB5 A;  4ZNG A;  2BB7 A;  4IEC A;  4S00 A;  1WLR A;  4S2R P;  5CDV A;  1YW9 A;  4KM3 A;  4U6C A;  2GA2 A;  2GG2 A;  1R5G A;  4Z7M A;  4B28 A;  3CTZ A;  1C27 A;  4IDY A;  3FMR A;  4S01 A;  4PNC A;  3L7G A;  2ADU A;  3PKD A;  5CE6 A;  2BWT A;  1C23 A;  3BIQ A;  3TAV A;  2GGC A;  3MAT A;  4A6V A;  5CLS A;  1WL6 A;  5JI6 A;  1KQ0 A;  2BWU A;  4U75 A;  2P99 A;  1O0X A;  2EA2 A;  1Y1N A;  4OOK A;  4ZWO A;  4ZWP A;  2NQ7 A;  1KP0 A;  2EVM A;  2Q96 A;  5CIK A;  3FM3 A;  2V3X A;  5D6E A;  1M35 A;  2GZ5 A;  2Q95 A;  4R60 A;  1XGN A;  1XGS A;  2GG9 A;  4RGZ 1;  3MX6 A;  3IU9 A;  1WBQ A; 
#chains in the Genus database with same CATH topology
 4FO8 A;  2OAZ A;  4JUQ A;  4IU6 A;  4PV4 A;  2G6P A;  4RZZ A;  1C22 A;  2BWY A;  2NQ6 A;  4FUK A;  3RVA A;  2V3Y A;  2V3Z A;  1B6A A;  2B3L A;  4EGE A;  4IKS A;  3Q6D A;  4U69 A;  2EVC A;  1W7V A;  1BN5 A;  1QXY A;  2EA4 A;  4U6W A;  2GU5 A;  2GU7 A;  4U71 A;  4IPA A;  4HXX A;  1YJ3 A;  2Q92 A;  3PKE A;  4RZY A;  1W2M A;  2GU4 A;  5FCF A;  2GG5 A;  2GG0 A;  1R5H A;  4IF7 A;  1XGO A;  2DFI A;  1R58 A;  2BHA A;  3S6B A;  1XGM A;  2Q8K A;  2EVO A;  2ZSG A;  4FLI A;  5D6F A;  1B59 A;  2BWS A;  1C21 A;  3IU8 A;  5JFR A;  4U6J A;  4U6Z A;  2Q93 A;  3FMQ A;  1BOA A;  1XNZ A;  1WKM A;  2BWX A;  3PKA A;  3PKC A;  3ROR A;  2GG8 A;  4IKT A;  4IKR A;  5CDE A;  1N51 A;  2P9A A;  1C24 A;  2BHC A;  2BWW A;  3L24 A;  2HOW A;  5FCH A;  1YVM A;  5CDL A;  2Q94 A;  4S2T P;  5E5B A;  2BWV A;  1QZY A;  1QXZ A;  2GTX A;  1PV9 A;  2B3K A;  1YW7 A;  3BIP A;  3MR1 A;  5CNX A;  4U6E A;  2GU6 A;  2GGB A;  3BIT A;  1JAW A;  1WL9 A;  4U76 A;  2BN7 A;  1MAT A;  2P98 A;  4FLK A;  2GG7 A;  4MAT A;  4QR8 A;  1A16 A;  2BHD A;  3PKB A;  3TB5 A;  5JHU A;  2GG3 A;  3IG4 A;  4FLJ A;  1KQ9 A;  3CB6 A;  4FKC A;  1WN1 A;  3D27 A;  4IKU A;  2V6C A;  2OKN A;  4ZWU A;  1WY2 A;  1CHM A;  1QXW A;  4A6W A;  2IW2 A;  2BH3 A;  2MAT A;  2B3H A;  1YW8 A;  4FLL A;  4U73 A;  3IU7 A;  4U1B A;  4FO7 A;  4U70 A;  2BHB A;  3CB5 A;  4ZNG A;  2BB7 A;  4IEC A;  4S00 A;  1WLR A;  4S2R P;  5CDV A;  1YW9 A;  4KM3 A;  4U6C A;  2GA2 A;  2GG2 A;  1R5G A;  4Z7M A;  4B28 A;  3CTZ A;  1C27 A;  4IDY A;  3FMR A;  4S01 A;  4PNC A;  3L7G A;  2ADU A;  3PKD A;  5CE6 A;  2BWT A;  1C23 A;  3BIQ A;  3TAV A;  2GGC A;  3MAT A;  4A6V A;  5CLS A;  1WL6 A;  5JI6 A;  1KQ0 A;  2BWU A;  4U75 A;  2P99 A;  1O0X A;  2EA2 A;  1Y1N A;  4OOK A;  4ZWO A;  4ZWP A;  2NQ7 A;  1KP0 A;  2EVM A;  2Q96 A;  5CIK A;  3FM3 A;  2V3X A;  5D6E A;  1M35 A;  2GZ5 A;  2Q95 A;  4R60 A;  1XGN A;  1XGS A;  2GG9 A;  4RGZ 1;  3MX6 A;  3IU9 A;  1WBQ A; 
#chains in the Genus database with same CATH homology
 4FO8 A;  2OAZ A;  4JUQ A;  4IU6 A;  4PV4 A;  2G6P A;  4RZZ A;  1C22 A;  2BWY A;  2NQ6 A;  4FUK A;  3RVA A;  2V3Y A;  2V3Z A;  1B6A A;  2B3L A;  4EGE A;  4IKS A;  3Q6D A;  4U69 A;  2EVC A;  1W7V A;  1BN5 A;  1QXY A;  2EA4 A;  4U6W A;  2GU5 A;  2GU7 A;  4U71 A;  4IPA A;  4HXX A;  1YJ3 A;  2Q92 A;  3PKE A;  4RZY A;  1W2M A;  2GU4 A;  5FCF A;  2GG5 A;  2GG0 A;  1R5H A;  4IF7 A;  1XGO A;  2DFI A;  1R58 A;  2BHA A;  3S6B A;  1XGM A;  2Q8K A;  2EVO A;  2ZSG A;  4FLI A;  5D6F A;  1B59 A;  2BWS A;  1C21 A;  3IU8 A;  5JFR A;  4U6J A;  4U6Z A;  2Q93 A;  3FMQ A;  1BOA A;  1XNZ A;  1WKM A;  2BWX A;  3PKA A;  3PKC A;  3ROR A;  2GG8 A;  4IKT A;  4IKR A;  5CDE A;  1N51 A;  2P9A A;  1C24 A;  2BHC A;  2BWW A;  3L24 A;  2HOW A;  5FCH A;  1YVM A;  5CDL A;  2Q94 A;  4S2T P;  5E5B A;  2BWV A;  1QZY A;  1QXZ A;  2GTX A;  1PV9 A;  2B3K A;  1YW7 A;  3BIP A;  3MR1 A;  5CNX A;  4U6E A;  2GU6 A;  2GGB A;  3BIT A;  1JAW A;  1WL9 A;  4U76 A;  2BN7 A;  1MAT A;  2P98 A;  4FLK A;  2GG7 A;  4MAT A;  4QR8 A;  1A16 A;  2BHD A;  3PKB A;  3TB5 A;  5JHU A;  2GG3 A;  3IG4 A;  4FLJ A;  1KQ9 A;  3CB6 A;  4FKC A;  1WN1 A;  3D27 A;  4IKU A;  2V6C A;  2OKN A;  4ZWU A;  1WY2 A;  1CHM A;  1QXW A;  4A6W A;  2IW2 A;  2BH3 A;  2MAT A;  2B3H A;  1YW8 A;  4FLL A;  4U73 A;  3IU7 A;  4U1B A;  4FO7 A;  4U70 A;  2BHB A;  3CB5 A;  4ZNG A;  2BB7 A;  4IEC A;  4S00 A;  1WLR A;  4S2R P;  5CDV A;  1YW9 A;  4KM3 A;  4U6C A;  2GA2 A;  2GG2 A;  1R5G A;  4Z7M A;  4B28 A;  3CTZ A;  1C27 A;  4IDY A;  3FMR A;  4S01 A;  4PNC A;  3L7G A;  2ADU A;  3PKD A;  5CE6 A;  2BWT A;  1C23 A;  3BIQ A;  3TAV A;  2GGC A;  3MAT A;  4A6V A;  5CLS A;  1WL6 A;  5JI6 A;  1KQ0 A;  2BWU A;  4U75 A;  2P99 A;  1O0X A;  2EA2 A;  1Y1N A;  4OOK A;  4ZWO A;  4ZWP A;  2NQ7 A;  1KP0 A;  2EVM A;  2Q96 A;  5CIK A;  3FM3 A;  2V3X A;  5D6E A;  1M35 A;  2GZ5 A;  2Q95 A;  4R60 A;  1XGN A;  1XGS A;  2GG9 A;  4RGZ 1;  3MX6 A;  3IU9 A;  1WBQ A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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