1Y1NA

Identification of sh3 motif in m. tuberculosis methionine aminopeptidase suggests a mode of interaction with the ribosome
Total Genus 86
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
86
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Mycobacterium tuberculosis
publication title Identification of an SH3-Binding Motif in a New Class of Methionine Aminopeptidases from Mycobacterium tuberculosis Suggests a Mode of Interaction with the Ribosome
pubmed doi rcsb
molecule keywords Methionine aminopeptidase 1B
total genus 86
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2004-11-18

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1y1nA01
2Q94A 1QZYA 1B6AA 2EVCA 2MATA 1R5HA 1XNZA 4PNCA 1YW8A 1BOAA 4U76A 2V3XA 2GG5A 3PKAA 4U70A 4A6WA 5CDVA 4RZZA 4FO7A 1W2MA 3IU8A 4ZNGA 2P98A 3PKEA 4FUKA 4U69A 4U6CA 4HXXA 1WN1A 3IU7A 4OOKA 5CE6A 3S6BA 3FMQA 5JFRA 1WBQA 1M35A 2GG9A 2GA2A 4U6WA 3MATA 4Z7MA 2BHAA 5FCHA 2GGBA 1QXYA 2GG7A 2GU5A 3L7GA 1XGMA 3MR1A 1C21A 3FMRA 4IKRA 3BIQA 2BWWA 2GZ5A 4U6ZA 2OKNA 4FO8A 4U6EA 1YW7A 4IKTA 2BHCA 2B3HA 2V3YA 4U6JA 5CNXA 2P99A 1XGNA 2BHBA 4ZWUA 2BN7A 1WL6A 2BWYA 1WKMA 1XGSA 5CDEA 4FLJA 2BWUA 3BITA 4FLIA 2IW2A 1YW9A 2Q92A 2BWSA 4MATA 2DFIA 2B3LA 4U71A 2NQ7A 4A6VA 3CB5A 2P9AA 2GU7A 2BHDA 5D6FA 1KQ9A 5CDLA 4RGZ1 2Q95A 1C23A 2V6CA 4EGEA 2BWVA 1WL9A 1JAWA 3CB6A 3RVAA 4ZWPA 4IF7A 4IPAA 2ZSGA 1R58A 5E5BA 1A16A 2B3KA 1WLRA 2EVMA 1C27A 1YVMA 3BIPA 3FM3A 4FKCA 4IU6A 1B59A 1N51A 3PKCA 4ZWOA 4KM3A 1QXZA 2GGCA 4QR8A 4U73A 3IU9A 1O0XA 4IDYA 2EA4A 1C24A 3TB5A 1MATA 2ADUA 3L24A 1QXWA 3PKDA 4IKUA 5FCFA 3CTZA 4S00A 2GG2A 2GU6A 4JUQA 1WY2A 2BB7A 2EA2A 2GG3A 2Q93A 2GU4A 3PKBA 2EVOA 4FLKA 1R5GA 1CHMA 4IKSA 2Q96A 2BH3A 4S01A 5D6EA 2G6PA 2HOWA 2Q8KA 4PV4A 2GG0A 2GTXA 4IECA 1PV9A 2NQ6A 3Q6DA 4R60A 4RZYA 1XGOA 2OAZA 4S2TP 3IG4A 4S2RP 1C22A 2BWTA 5CLSA 5JI6A 3D27A 5JHUA 4U1BA 1W7VA 2BWXA 3MX6A 1KP0A 1KQ0A 3TAVA 2GG8A 4FLLA 5CIKA 1Y1NA 1YJ3A 2V3ZA 4U75A 4B28A 1BN5A 3RORA
chains in the Genus database with same CATH superfamily
2Q94A 1QZYA 1B6AA 2EVCA 2MATA 1R5HA 1XNZA 4PNCA 1YW8A 1BOAA 4U76A 2V3XA 2GG5A 3PKAA 4U70A 4A6WA 5CDVA 4RZZA 4FO7A 1W2MA 3IU8A 4ZNGA 2P98A 3PKEA 4FUKA 4U69A 4U6CA 4HXXA 1WN1A 3IU7A 4OOKA 5CE6A 3S6BA 3FMQA 5JFRA 1WBQA 1M35A 2GG9A 2GA2A 4U6WA 3MATA 4Z7MA 2BHAA 5FCHA 2GGBA 1QXYA 2GG7A 2GU5A 3L7GA 1XGMA 3MR1A 1C21A 3FMRA 4IKRA 3BIQA 2BWWA 2GZ5A 4U6ZA 2OKNA 4FO8A 4U6EA 1YW7A 4IKTA 2BHCA 2B3HA 2V3YA 4U6JA 5CNXA 2P99A 1XGNA 2BHBA 4ZWUA 2BN7A 1WL6A 2BWYA 1WKMA 1XGSA 5CDEA 4FLJA 2BWUA 3BITA 4FLIA 2IW2A 1YW9A 2Q92A 2BWSA 4MATA 2DFIA 2B3LA 4U71A 2NQ7A 4A6VA 3CB5A 2P9AA 2GU7A 2BHDA 5D6FA 1KQ9A 5CDLA 4RGZ1 2Q95A 1C23A 2V6CA 4EGEA 2BWVA 1WL9A 1JAWA 3CB6A 3RVAA 4ZWPA 4IF7A 4IPAA 2ZSGA 1R58A 5E5BA 1A16A 2B3KA 1WLRA 2EVMA 1C27A 1YVMA 3BIPA 3FM3A 4FKCA 4IU6A 1B59A 1N51A 3PKCA 4ZWOA 4KM3A 1QXZA 2GGCA 4QR8A 4U73A 3IU9A 1O0XA 4IDYA 2EA4A 1C24A 3TB5A 1MATA 2ADUA 3L24A 1QXWA 3PKDA 4IKUA 5FCFA 3CTZA 4S00A 2GG2A 2GU6A 4JUQA 1WY2A 2BB7A 2EA2A 2GG3A 2Q93A 2GU4A 3PKBA 2EVOA 4FLKA 1R5GA 1CHMA 4IKSA 2Q96A 2BH3A 4S01A 5D6EA 2G6PA 2HOWA 2Q8KA 4PV4A 2GG0A 2GTXA 4IECA 1PV9A 2NQ6A 3Q6DA 4R60A 4RZYA 1XGOA 2OAZA 4S2TP 3IG4A 4S2RP 1C22A 2BWTA 5CLSA 5JI6A 3D27A 5JHUA 4U1BA 1W7VA 2BWXA 3MX6A 1KP0A 1KQ0A 3TAVA 2GG8A 4FLLA 5CIKA 1Y1NA 1YJ3A 2V3ZA 4U75A 4B28A 1BN5A 3RORA
chains in the Genus database with same CATH topology
2Q94A 1QZYA 1B6AA 2EVCA 2MATA 1R5HA 1XNZA 4PNCA 1YW8A 1BOAA 4U76A 2V3XA 2GG5A 3PKAA 4U70A 4A6WA 5CDVA 4RZZA 4FO7A 1W2MA 3IU8A 4ZNGA 2P98A 3PKEA 4FUKA 4U69A 4U6CA 4HXXA 1WN1A 3IU7A 4OOKA 5CE6A 3S6BA 3FMQA 5JFRA 1WBQA 1M35A 2GG9A 2GA2A 4U6WA 3MATA 4Z7MA 2BHAA 5FCHA 2GGBA 1QXYA 2GG7A 2GU5A 3L7GA 1XGMA 3MR1A 1C21A 3FMRA 4IKRA 3BIQA 2BWWA 2GZ5A 4U6ZA 2OKNA 4FO8A 4U6EA 1YW7A 4IKTA 2BHCA 2B3HA 2V3YA 4U6JA 5CNXA 2P99A 1XGNA 2BHBA 4ZWUA 2BN7A 1WL6A 2BWYA 1WKMA 1XGSA 5CDEA 4FLJA 2BWUA 3BITA 4FLIA 2IW2A 1YW9A 2Q92A 2BWSA 4MATA 2DFIA 2B3LA 4U71A 2NQ7A 4A6VA 3CB5A 2P9AA 2GU7A 2BHDA 5D6FA 1KQ9A 5CDLA 4RGZ1 2Q95A 1C23A 2V6CA 4EGEA 2BWVA 1WL9A 1JAWA 3CB6A 3RVAA 4ZWPA 4IF7A 4IPAA 2ZSGA 1R58A 5E5BA 1A16A 2B3KA 1WLRA 2EVMA 1C27A 1YVMA 3BIPA 3FM3A 4FKCA 4IU6A 1B59A 1N51A 3PKCA 4ZWOA 4KM3A 1QXZA 2GGCA 4QR8A 4U73A 3IU9A 1O0XA 4IDYA 2EA4A 1C24A 3TB5A 1MATA 2ADUA 3L24A 1QXWA 3PKDA 4IKUA 5FCFA 3CTZA 4S00A 2GG2A 2GU6A 4JUQA 1WY2A 2BB7A 2EA2A 2GG3A 2Q93A 2GU4A 3PKBA 2EVOA 4FLKA 1R5GA 1CHMA 4IKSA 2Q96A 2BH3A 4S01A 5D6EA 2G6PA 2HOWA 2Q8KA 4PV4A 2GG0A 2GTXA 4IECA 1PV9A 2NQ6A 3Q6DA 4R60A 4RZYA 1XGOA 2OAZA 4S2TP 3IG4A 4S2RP 1C22A 2BWTA 5CLSA 5JI6A 3D27A 5JHUA 4U1BA 1W7VA 2BWXA 3MX6A 1KP0A 1KQ0A 3TAVA 2GG8A 4FLLA 5CIKA 1Y1NA 1YJ3A 2V3ZA 4U75A 4B28A 1BN5A 3RORA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q94 A;  1QZY A;  1B6A A;  2EVC A;  2MAT A;  1R5H A;  1XNZ A;  4PNC A;  1YW8 A;  1BOA A;  4U76 A;  2V3X A;  2GG5 A;  3PKA A;  4U70 A;  4A6W A;  5CDV A;  4RZZ A;  4FO7 A;  1W2M A;  3IU8 A;  4ZNG A;  2P98 A;  3PKE A;  4FUK A;  4U69 A;  4U6C A;  4HXX A;  1WN1 A;  3IU7 A;  4OOK A;  5CE6 A;  3S6B A;  3FMQ A;  5JFR A;  1WBQ A;  1M35 A;  2GG9 A;  2GA2 A;  4U6W A;  3MAT A;  4Z7M A;  2BHA A;  5FCH A;  2GGB A;  1QXY A;  2GG7 A;  2GU5 A;  3L7G A;  1XGM A;  3MR1 A;  1C21 A;  3FMR A;  4IKR A;  3BIQ A;  2BWW A;  2GZ5 A;  4U6Z A;  2OKN A;  4FO8 A;  4U6E A;  1YW7 A;  4IKT A;  2BHC A;  2B3H A;  2V3Y A;  4U6J A;  5CNX A;  2P99 A;  1XGN A;  2BHB A;  4ZWU A;  2BN7 A;  1WL6 A;  2BWY A;  1WKM A;  1XGS A;  5CDE A;  4FLJ A;  2BWU A;  3BIT A;  4FLI A;  2IW2 A;  1YW9 A;  2Q92 A;  2BWS A;  4MAT A;  2DFI A;  2B3L A;  4U71 A;  2NQ7 A;  4A6V A;  3CB5 A;  2P9A A;  2GU7 A;  2BHD A;  5D6F A;  1KQ9 A;  5CDL A;  4RGZ 1;  2Q95 A;  1C23 A;  2V6C A;  4EGE A;  2BWV A;  1WL9 A;  1JAW A;  3CB6 A;  3RVA A;  4ZWP A;  4IF7 A;  4IPA A;  2ZSG A;  1R58 A;  5E5B A;  1A16 A;  2B3K A;  1WLR A;  2EVM A;  1C27 A;  1YVM A;  3BIP A;  3FM3 A;  4FKC A;  4IU6 A;  1B59 A;  1N51 A;  3PKC A;  4ZWO A;  4KM3 A;  1QXZ A;  2GGC A;  4QR8 A;  4U73 A;  3IU9 A;  1O0X A;  4IDY A;  2EA4 A;  1C24 A;  3TB5 A;  1MAT A;  2ADU A;  3L24 A;  1QXW A;  3PKD A;  4IKU A;  5FCF A;  3CTZ A;  4S00 A;  2GG2 A;  2GU6 A;  4JUQ A;  1WY2 A;  2BB7 A;  2EA2 A;  2GG3 A;  2Q93 A;  2GU4 A;  3PKB A;  2EVO A;  4FLK A;  1R5G A;  1CHM A;  4IKS A;  2Q96 A;  2BH3 A;  4S01 A;  5D6E A;  2G6P A;  2HOW A;  2Q8K A;  4PV4 A;  2GG0 A;  2GTX A;  4IEC A;  1PV9 A;  2NQ6 A;  3Q6D A;  4R60 A;  4RZY A;  1XGO A;  2OAZ A;  4S2T P;  3IG4 A;  4S2R P;  1C22 A;  2BWT A;  5CLS A;  5JI6 A;  3D27 A;  5JHU A;  4U1B A;  1W7V A;  2BWX A;  3MX6 A;  1KP0 A;  1KQ0 A;  3TAV A;  2GG8 A;  4FLL A;  5CIK A;  1Y1N A;  1YJ3 A;  2V3Z A;  4U75 A;  4B28 A;  1BN5 A;  3ROR A; 
#chains in the Genus database with same CATH topology
 2Q94 A;  1QZY A;  1B6A A;  2EVC A;  2MAT A;  1R5H A;  1XNZ A;  4PNC A;  1YW8 A;  1BOA A;  4U76 A;  2V3X A;  2GG5 A;  3PKA A;  4U70 A;  4A6W A;  5CDV A;  4RZZ A;  4FO7 A;  1W2M A;  3IU8 A;  4ZNG A;  2P98 A;  3PKE A;  4FUK A;  4U69 A;  4U6C A;  4HXX A;  1WN1 A;  3IU7 A;  4OOK A;  5CE6 A;  3S6B A;  3FMQ A;  5JFR A;  1WBQ A;  1M35 A;  2GG9 A;  2GA2 A;  4U6W A;  3MAT A;  4Z7M A;  2BHA A;  5FCH A;  2GGB A;  1QXY A;  2GG7 A;  2GU5 A;  3L7G A;  1XGM A;  3MR1 A;  1C21 A;  3FMR A;  4IKR A;  3BIQ A;  2BWW A;  2GZ5 A;  4U6Z A;  2OKN A;  4FO8 A;  4U6E A;  1YW7 A;  4IKT A;  2BHC A;  2B3H A;  2V3Y A;  4U6J A;  5CNX A;  2P99 A;  1XGN A;  2BHB A;  4ZWU A;  2BN7 A;  1WL6 A;  2BWY A;  1WKM A;  1XGS A;  5CDE A;  4FLJ A;  2BWU A;  3BIT A;  4FLI A;  2IW2 A;  1YW9 A;  2Q92 A;  2BWS A;  4MAT A;  2DFI A;  2B3L A;  4U71 A;  2NQ7 A;  4A6V A;  3CB5 A;  2P9A A;  2GU7 A;  2BHD A;  5D6F A;  1KQ9 A;  5CDL A;  4RGZ 1;  2Q95 A;  1C23 A;  2V6C A;  4EGE A;  2BWV A;  1WL9 A;  1JAW A;  3CB6 A;  3RVA A;  4ZWP A;  4IF7 A;  4IPA A;  2ZSG A;  1R58 A;  5E5B A;  1A16 A;  2B3K A;  1WLR A;  2EVM A;  1C27 A;  1YVM A;  3BIP A;  3FM3 A;  4FKC A;  4IU6 A;  1B59 A;  1N51 A;  3PKC A;  4ZWO A;  4KM3 A;  1QXZ A;  2GGC A;  4QR8 A;  4U73 A;  3IU9 A;  1O0X A;  4IDY A;  2EA4 A;  1C24 A;  3TB5 A;  1MAT A;  2ADU A;  3L24 A;  1QXW A;  3PKD A;  4IKU A;  5FCF A;  3CTZ A;  4S00 A;  2GG2 A;  2GU6 A;  4JUQ A;  1WY2 A;  2BB7 A;  2EA2 A;  2GG3 A;  2Q93 A;  2GU4 A;  3PKB A;  2EVO A;  4FLK A;  1R5G A;  1CHM A;  4IKS A;  2Q96 A;  2BH3 A;  4S01 A;  5D6E A;  2G6P A;  2HOW A;  2Q8K A;  4PV4 A;  2GG0 A;  2GTX A;  4IEC A;  1PV9 A;  2NQ6 A;  3Q6D A;  4R60 A;  4RZY A;  1XGO A;  2OAZ A;  4S2T P;  3IG4 A;  4S2R P;  1C22 A;  2BWT A;  5CLS A;  5JI6 A;  3D27 A;  5JHU A;  4U1B A;  1W7V A;  2BWX A;  3MX6 A;  1KP0 A;  1KQ0 A;  3TAV A;  2GG8 A;  4FLL A;  5CIK A;  1Y1N A;  1YJ3 A;  2V3Z A;  4U75 A;  4B28 A;  1BN5 A;  3ROR A; 
#chains in the Genus database with same CATH homology
 2Q94 A;  1QZY A;  1B6A A;  2EVC A;  2MAT A;  1R5H A;  1XNZ A;  4PNC A;  1YW8 A;  1BOA A;  4U76 A;  2V3X A;  2GG5 A;  3PKA A;  4U70 A;  4A6W A;  5CDV A;  4RZZ A;  4FO7 A;  1W2M A;  3IU8 A;  4ZNG A;  2P98 A;  3PKE A;  4FUK A;  4U69 A;  4U6C A;  4HXX A;  1WN1 A;  3IU7 A;  4OOK A;  5CE6 A;  3S6B A;  3FMQ A;  5JFR A;  1WBQ A;  1M35 A;  2GG9 A;  2GA2 A;  4U6W A;  3MAT A;  4Z7M A;  2BHA A;  5FCH A;  2GGB A;  1QXY A;  2GG7 A;  2GU5 A;  3L7G A;  1XGM A;  3MR1 A;  1C21 A;  3FMR A;  4IKR A;  3BIQ A;  2BWW A;  2GZ5 A;  4U6Z A;  2OKN A;  4FO8 A;  4U6E A;  1YW7 A;  4IKT A;  2BHC A;  2B3H A;  2V3Y A;  4U6J A;  5CNX A;  2P99 A;  1XGN A;  2BHB A;  4ZWU A;  2BN7 A;  1WL6 A;  2BWY A;  1WKM A;  1XGS A;  5CDE A;  4FLJ A;  2BWU A;  3BIT A;  4FLI A;  2IW2 A;  1YW9 A;  2Q92 A;  2BWS A;  4MAT A;  2DFI A;  2B3L A;  4U71 A;  2NQ7 A;  4A6V A;  3CB5 A;  2P9A A;  2GU7 A;  2BHD A;  5D6F A;  1KQ9 A;  5CDL A;  4RGZ 1;  2Q95 A;  1C23 A;  2V6C A;  4EGE A;  2BWV A;  1WL9 A;  1JAW A;  3CB6 A;  3RVA A;  4ZWP A;  4IF7 A;  4IPA A;  2ZSG A;  1R58 A;  5E5B A;  1A16 A;  2B3K A;  1WLR A;  2EVM A;  1C27 A;  1YVM A;  3BIP A;  3FM3 A;  4FKC A;  4IU6 A;  1B59 A;  1N51 A;  3PKC A;  4ZWO A;  4KM3 A;  1QXZ A;  2GGC A;  4QR8 A;  4U73 A;  3IU9 A;  1O0X A;  4IDY A;  2EA4 A;  1C24 A;  3TB5 A;  1MAT A;  2ADU A;  3L24 A;  1QXW A;  3PKD A;  4IKU A;  5FCF A;  3CTZ A;  4S00 A;  2GG2 A;  2GU6 A;  4JUQ A;  1WY2 A;  2BB7 A;  2EA2 A;  2GG3 A;  2Q93 A;  2GU4 A;  3PKB A;  2EVO A;  4FLK A;  1R5G A;  1CHM A;  4IKS A;  2Q96 A;  2BH3 A;  4S01 A;  5D6E A;  2G6P A;  2HOW A;  2Q8K A;  4PV4 A;  2GG0 A;  2GTX A;  4IEC A;  1PV9 A;  2NQ6 A;  3Q6D A;  4R60 A;  4RZY A;  1XGO A;  2OAZ A;  4S2T P;  3IG4 A;  4S2R P;  1C22 A;  2BWT A;  5CLS A;  5JI6 A;  3D27 A;  5JHU A;  4U1B A;  1W7V A;  2BWX A;  3MX6 A;  1KP0 A;  1KQ0 A;  3TAV A;  2GG8 A;  4FLL A;  5CIK A;  1Y1N A;  1YJ3 A;  2V3Z A;  4U75 A;  4B28 A;  1BN5 A;  3ROR A; 
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similar chains in the Genus database (?% sequence similarity)
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#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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