1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
2GU5A 2EA4A 3L7GA 2EVOA 2GG7A 4IECA 1A16A 2GGBA 3S6BA 2Q92A 3IG4A 2Q96A 1W7VA 4U73A 5CDLA 5JFRA 2BHBA 4MATA 3IU9A 4FKCA 2V3XA 2G6PA 3MR1A 2EVCA 2BWTA 2GG9A 2GTXA 1C22A 1QXZA 1B59A 1XGNA 2Q95A 4FUKA 5CDVA 4IU6A 4S01A 1JAWA 1XNZA 4IPAA 4JUQA 3RVAA 3CB6A 4IKTA 4KM3A 2ZSGA 3PKBA 4RZYA 1PV9A 3BIPA 1B6AA 3CB5A 4IDYA 1KP0A 2BH3A 2B3HA 2GG2A 1C24A 2OKNA 1WN1A 4IKUA 1WL6A 4PNCA 2BHAA 4OOKA 3D27A 1N51A 5JHUA 3RORA 4S00A 2BWWA 4QR8A 1WY2A 4S2TP 4ZNGA 4FLIA 1KQ9A 4U6CA 1C27A 4U76A 2EVMA 5JI6A 2HOWA 1WBQA 1YVMA 2Q93A 4U75A 4ZWUA 1WLRA 3CTZA 1M35A 2BB7A 4Z7MA 2BWVA 4FO8A 2MATA 3FM3A 1R5HA 4U70A 5FCHA 5CDEA 1Y1NA 2BWSA 4U1BA 1C21A 2P9AA 3IU8A 2B3LA 4PV4A 4RZZA 2GZ5A 1XGSA 3FMRA 2NQ6A 3L24A 2B3KA 5D6EA 1C23A 3PKCA 2OAZA 1KQ0A 3PKEA 5CNXA 3Q6DA 4EGEA 2BHCA 2NQ7A 1BN5A 2Q94A 4A6WA 4B28A 1R5GA 4U6JA 1YW9A 3TAVA 4FLLA 3MATA 4U6WA 2GU6A 4U69A 1XGOA 2GU7A 1YW8A 5CIKA 5D6FA 5CLSA 4FLJA 4FO7A 4IKSA 2GA2A 4IKRA 5CE6A 2P98A 2GG8A 4RGZ1 5FCFA 1WKMA 2BWUA 4R60A 1WL9A 2DFIA 3BIQA 4HXXA 1YW7A 3TB5A 1XGMA 2BHDA 2Q8KA 4S2RP 2GG3A 2GG0A 3IU7A 5E5BA 2V6CA 4U6ZA 2BWYA 1YJ3A 1MATA 3BITA 1R58A 4A6VA 3MX6A 4FLKA 2GGCA 1BOAA 2BN7A 1QXWA 1QZYA 4ZWOA 1O0XA 2EA2A 4U71A 2GG5A 2GU4A 4ZWPA 2BWXA 4IF7A 4U6EA 1CHMA 3PKDA 2P99A 3PKAA 3FMQA 2V3YA 1QXYA 2IW2A 2V3ZA 2ADUA 1W2MA
chains in the Genus database with same CATH superfamily
2GU5A 2EA4A 3L7GA 2EVOA 2GG7A 4IECA 1A16A 2GGBA 3S6BA 2Q92A 3IG4A 2Q96A 1W7VA 4U73A 5CDLA 5JFRA 2BHBA 4MATA 3IU9A 4FKCA 2V3XA 2G6PA 3MR1A 2EVCA 2BWTA 2GG9A 2GTXA 1C22A 1QXZA 1B59A 1XGNA 2Q95A 4FUKA 5CDVA 4IU6A 4S01A 1JAWA 1XNZA 4IPAA 4JUQA 3RVAA 3CB6A 4IKTA 4KM3A 2ZSGA 3PKBA 4RZYA 1PV9A 3BIPA 1B6AA 3CB5A 4IDYA 1KP0A 2BH3A 2B3HA 2GG2A 1C24A 2OKNA 1WN1A 4IKUA 1WL6A 4PNCA 2BHAA 4OOKA 3D27A 1N51A 5JHUA 3RORA 4S00A 2BWWA 4QR8A 1WY2A 4S2TP 4ZNGA 4FLIA 1KQ9A 4U6CA 1C27A 4U76A 2EVMA 5JI6A 2HOWA 1WBQA 1YVMA 2Q93A 4U75A 4ZWUA 1WLRA 3CTZA 1M35A 2BB7A 4Z7MA 2BWVA 4FO8A 2MATA 3FM3A 1R5HA 4U70A 5FCHA 5CDEA 1Y1NA 2BWSA 4U1BA 1C21A 2P9AA 3IU8A 2B3LA 4PV4A 4RZZA 2GZ5A 1XGSA 3FMRA 2NQ6A 3L24A 2B3KA 5D6EA 1C23A 3PKCA 2OAZA 1KQ0A 3PKEA 5CNXA 3Q6DA 4EGEA 2BHCA 2NQ7A 1BN5A 2Q94A 4A6WA 4B28A 1R5GA 4U6JA 1YW9A 3TAVA 4FLLA 3MATA 4U6WA 2GU6A 4U69A 1XGOA 2GU7A 1YW8A 5CIKA 5D6FA 5CLSA 4FLJA 4FO7A 4IKSA 2GA2A 4IKRA 5CE6A 2P98A 2GG8A 4RGZ1 5FCFA 1WKMA 2BWUA 4R60A 1WL9A 2DFIA 3BIQA 4HXXA 1YW7A 3TB5A 1XGMA 2BHDA 2Q8KA 4S2RP 2GG3A 2GG0A 3IU7A 5E5BA 2V6CA 4U6ZA 2BWYA 1YJ3A 1MATA 3BITA 1R58A 4A6VA 3MX6A 4FLKA 2GGCA 1BOAA 2BN7A 1QXWA 1QZYA 4ZWOA 1O0XA 2EA2A 4U71A 2GG5A 2GU4A 4ZWPA 2BWXA 4IF7A 4U6EA 1CHMA 3PKDA 2P99A 3PKAA 3FMQA 2V3YA 1QXYA 2IW2A 2V3ZA 2ADUA 1W2MA
chains in the Genus database with same CATH topology
2GU5A 2EA4A 3L7GA 2EVOA 2GG7A 4IECA 1A16A 2GGBA 3S6BA 2Q92A 3IG4A 2Q96A 1W7VA 4U73A 5CDLA 5JFRA 2BHBA 4MATA 3IU9A 4FKCA 2V3XA 2G6PA 3MR1A 2EVCA 2BWTA 2GG9A 2GTXA 1C22A 1QXZA 1B59A 1XGNA 2Q95A 4FUKA 5CDVA 4IU6A 4S01A 1JAWA 1XNZA 4IPAA 4JUQA 3RVAA 3CB6A 4IKTA 4KM3A 2ZSGA 3PKBA 4RZYA 1PV9A 3BIPA 1B6AA 3CB5A 4IDYA 1KP0A 2BH3A 2B3HA 2GG2A 1C24A 2OKNA 1WN1A 4IKUA 1WL6A 4PNCA 2BHAA 4OOKA 3D27A 1N51A 5JHUA 3RORA 4S00A 2BWWA 4QR8A 1WY2A 4S2TP 4ZNGA 4FLIA 1KQ9A 4U6CA 1C27A 4U76A 2EVMA 5JI6A 2HOWA 1WBQA 1YVMA 2Q93A 4U75A 4ZWUA 1WLRA 3CTZA 1M35A 2BB7A 4Z7MA 2BWVA 4FO8A 2MATA 3FM3A 1R5HA 4U70A 5FCHA 5CDEA 1Y1NA 2BWSA 4U1BA 1C21A 2P9AA 3IU8A 2B3LA 4PV4A 4RZZA 2GZ5A 1XGSA 3FMRA 2NQ6A 3L24A 2B3KA 5D6EA 1C23A 3PKCA 2OAZA 1KQ0A 3PKEA 5CNXA 3Q6DA 4EGEA 2BHCA 2NQ7A 1BN5A 2Q94A 4A6WA 4B28A 1R5GA 4U6JA 1YW9A 3TAVA 4FLLA 3MATA 4U6WA 2GU6A 4U69A 1XGOA 2GU7A 1YW8A 5CIKA 5D6FA 5CLSA 4FLJA 4FO7A 4IKSA 2GA2A 4IKRA 5CE6A 2P98A 2GG8A 4RGZ1 5FCFA 1WKMA 2BWUA 4R60A 1WL9A 2DFIA 3BIQA 4HXXA 1YW7A 3TB5A 1XGMA 2BHDA 2Q8KA 4S2RP 2GG3A 2GG0A 3IU7A 5E5BA 2V6CA 4U6ZA 2BWYA 1YJ3A 1MATA 3BITA 1R58A 4A6VA 3MX6A 4FLKA 2GGCA 1BOAA 2BN7A 1QXWA 1QZYA 4ZWOA 1O0XA 2EA2A 4U71A 2GG5A 2GU4A 4ZWPA 2BWXA 4IF7A 4U6EA 1CHMA 3PKDA 2P99A 3PKAA 3FMQA 2V3YA 1QXYA 2IW2A 2V3ZA 2ADUA 1W2MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GU5 A;  2EA4 A;  3L7G A;  2EVO A;  2GG7 A;  4IEC A;  1A16 A;  2GGB A;  3S6B A;  2Q92 A;  3IG4 A;  2Q96 A;  1W7V A;  4U73 A;  5CDL A;  5JFR A;  2BHB A;  4MAT A;  3IU9 A;  4FKC A;  2V3X A;  2G6P A;  3MR1 A;  2EVC A;  2BWT A;  2GG9 A;  2GTX A;  1C22 A;  1QXZ A;  1B59 A;  1XGN A;  2Q95 A;  4FUK A;  5CDV A;  4IU6 A;  4S01 A;  1JAW A;  1XNZ A;  4IPA A;  4JUQ A;  3RVA A;  3CB6 A;  4IKT A;  4KM3 A;  2ZSG A;  3PKB A;  4RZY A;  1PV9 A;  3BIP A;  1B6A A;  3CB5 A;  4IDY A;  1KP0 A;  2BH3 A;  2B3H A;  2GG2 A;  1C24 A;  2OKN A;  1WN1 A;  4IKU A;  1WL6 A;  4PNC A;  2BHA A;  4OOK A;  3D27 A;  1N51 A;  5JHU A;  3ROR A;  4S00 A;  2BWW A;  4QR8 A;  1WY2 A;  4S2T P;  4ZNG A;  4FLI A;  1KQ9 A;  4U6C A;  1C27 A;  4U76 A;  2EVM A;  5JI6 A;  2HOW A;  1WBQ A;  1YVM A;  2Q93 A;  4U75 A;  4ZWU A;  1WLR A;  3CTZ A;  1M35 A;  2BB7 A;  4Z7M A;  2BWV A;  4FO8 A;  2MAT A;  3FM3 A;  1R5H A;  4U70 A;  5FCH A;  5CDE A;  1Y1N A;  2BWS A;  4U1B A;  1C21 A;  2P9A A;  3IU8 A;  2B3L A;  4PV4 A;  4RZZ A;  2GZ5 A;  1XGS A;  3FMR A;  2NQ6 A;  3L24 A;  2B3K A;  5D6E A;  1C23 A;  3PKC A;  2OAZ A;  1KQ0 A;  3PKE A;  5CNX A;  3Q6D A;  4EGE A;  2BHC A;  2NQ7 A;  1BN5 A;  2Q94 A;  4A6W A;  4B28 A;  1R5G A;  4U6J A;  1YW9 A;  3TAV A;  4FLL A;  3MAT A;  4U6W A;  2GU6 A;  4U69 A;  1XGO A;  2GU7 A;  1YW8 A;  5CIK A;  5D6F A;  5CLS A;  4FLJ A;  4FO7 A;  4IKS A;  2GA2 A;  4IKR A;  5CE6 A;  2P98 A;  2GG8 A;  4RGZ 1;  5FCF A;  1WKM A;  2BWU A;  4R60 A;  1WL9 A;  2DFI A;  3BIQ A;  4HXX A;  1YW7 A;  3TB5 A;  1XGM A;  2BHD A;  2Q8K A;  4S2R P;  2GG3 A;  2GG0 A;  3IU7 A;  5E5B A;  2V6C A;  4U6Z A;  2BWY A;  1YJ3 A;  1MAT A;  3BIT A;  1R58 A;  4A6V A;  3MX6 A;  4FLK A;  2GGC A;  1BOA A;  2BN7 A;  1QXW A;  1QZY A;  4ZWO A;  1O0X A;  2EA2 A;  4U71 A;  2GG5 A;  2GU4 A;  4ZWP A;  2BWX A;  4IF7 A;  4U6E A;  1CHM A;  3PKD A;  2P99 A;  3PKA A;  3FMQ A;  2V3Y A;  1QXY A;  2IW2 A;  2V3Z A;  2ADU A;  1W2M A; 
#chains in the Genus database with same CATH topology
 2GU5 A;  2EA4 A;  3L7G A;  2EVO A;  2GG7 A;  4IEC A;  1A16 A;  2GGB A;  3S6B A;  2Q92 A;  3IG4 A;  2Q96 A;  1W7V A;  4U73 A;  5CDL A;  5JFR A;  2BHB A;  4MAT A;  3IU9 A;  4FKC A;  2V3X A;  2G6P A;  3MR1 A;  2EVC A;  2BWT A;  2GG9 A;  2GTX A;  1C22 A;  1QXZ A;  1B59 A;  1XGN A;  2Q95 A;  4FUK A;  5CDV A;  4IU6 A;  4S01 A;  1JAW A;  1XNZ A;  4IPA A;  4JUQ A;  3RVA A;  3CB6 A;  4IKT A;  4KM3 A;  2ZSG A;  3PKB A;  4RZY A;  1PV9 A;  3BIP A;  1B6A A;  3CB5 A;  4IDY A;  1KP0 A;  2BH3 A;  2B3H A;  2GG2 A;  1C24 A;  2OKN A;  1WN1 A;  4IKU A;  1WL6 A;  4PNC A;  2BHA A;  4OOK A;  3D27 A;  1N51 A;  5JHU A;  3ROR A;  4S00 A;  2BWW A;  4QR8 A;  1WY2 A;  4S2T P;  4ZNG A;  4FLI A;  1KQ9 A;  4U6C A;  1C27 A;  4U76 A;  2EVM A;  5JI6 A;  2HOW A;  1WBQ A;  1YVM A;  2Q93 A;  4U75 A;  4ZWU A;  1WLR A;  3CTZ A;  1M35 A;  2BB7 A;  4Z7M A;  2BWV A;  4FO8 A;  2MAT A;  3FM3 A;  1R5H A;  4U70 A;  5FCH A;  5CDE A;  1Y1N A;  2BWS A;  4U1B A;  1C21 A;  2P9A A;  3IU8 A;  2B3L A;  4PV4 A;  4RZZ A;  2GZ5 A;  1XGS A;  3FMR A;  2NQ6 A;  3L24 A;  2B3K A;  5D6E A;  1C23 A;  3PKC A;  2OAZ A;  1KQ0 A;  3PKE A;  5CNX A;  3Q6D A;  4EGE A;  2BHC A;  2NQ7 A;  1BN5 A;  2Q94 A;  4A6W A;  4B28 A;  1R5G A;  4U6J A;  1YW9 A;  3TAV A;  4FLL A;  3MAT A;  4U6W A;  2GU6 A;  4U69 A;  1XGO A;  2GU7 A;  1YW8 A;  5CIK A;  5D6F A;  5CLS A;  4FLJ A;  4FO7 A;  4IKS A;  2GA2 A;  4IKR A;  5CE6 A;  2P98 A;  2GG8 A;  4RGZ 1;  5FCF A;  1WKM A;  2BWU A;  4R60 A;  1WL9 A;  2DFI A;  3BIQ A;  4HXX A;  1YW7 A;  3TB5 A;  1XGM A;  2BHD A;  2Q8K A;  4S2R P;  2GG3 A;  2GG0 A;  3IU7 A;  5E5B A;  2V6C A;  4U6Z A;  2BWY A;  1YJ3 A;  1MAT A;  3BIT A;  1R58 A;  4A6V A;  3MX6 A;  4FLK A;  2GGC A;  1BOA A;  2BN7 A;  1QXW A;  1QZY A;  4ZWO A;  1O0X A;  2EA2 A;  4U71 A;  2GG5 A;  2GU4 A;  4ZWP A;  2BWX A;  4IF7 A;  4U6E A;  1CHM A;  3PKD A;  2P99 A;  3PKA A;  3FMQ A;  2V3Y A;  1QXY A;  2IW2 A;  2V3Z A;  2ADU A;  1W2M A; 
#chains in the Genus database with same CATH homology
 2GU5 A;  2EA4 A;  3L7G A;  2EVO A;  2GG7 A;  4IEC A;  1A16 A;  2GGB A;  3S6B A;  2Q92 A;  3IG4 A;  2Q96 A;  1W7V A;  4U73 A;  5CDL A;  5JFR A;  2BHB A;  4MAT A;  3IU9 A;  4FKC A;  2V3X A;  2G6P A;  3MR1 A;  2EVC A;  2BWT A;  2GG9 A;  2GTX A;  1C22 A;  1QXZ A;  1B59 A;  1XGN A;  2Q95 A;  4FUK A;  5CDV A;  4IU6 A;  4S01 A;  1JAW A;  1XNZ A;  4IPA A;  4JUQ A;  3RVA A;  3CB6 A;  4IKT A;  4KM3 A;  2ZSG A;  3PKB A;  4RZY A;  1PV9 A;  3BIP A;  1B6A A;  3CB5 A;  4IDY A;  1KP0 A;  2BH3 A;  2B3H A;  2GG2 A;  1C24 A;  2OKN A;  1WN1 A;  4IKU A;  1WL6 A;  4PNC A;  2BHA A;  4OOK A;  3D27 A;  1N51 A;  5JHU A;  3ROR A;  4S00 A;  2BWW A;  4QR8 A;  1WY2 A;  4S2T P;  4ZNG A;  4FLI A;  1KQ9 A;  4U6C A;  1C27 A;  4U76 A;  2EVM A;  5JI6 A;  2HOW A;  1WBQ A;  1YVM A;  2Q93 A;  4U75 A;  4ZWU A;  1WLR A;  3CTZ A;  1M35 A;  2BB7 A;  4Z7M A;  2BWV A;  4FO8 A;  2MAT A;  3FM3 A;  1R5H A;  4U70 A;  5FCH A;  5CDE A;  1Y1N A;  2BWS A;  4U1B A;  1C21 A;  2P9A A;  3IU8 A;  2B3L A;  4PV4 A;  4RZZ A;  2GZ5 A;  1XGS A;  3FMR A;  2NQ6 A;  3L24 A;  2B3K A;  5D6E A;  1C23 A;  3PKC A;  2OAZ A;  1KQ0 A;  3PKE A;  5CNX A;  3Q6D A;  4EGE A;  2BHC A;  2NQ7 A;  1BN5 A;  2Q94 A;  4A6W A;  4B28 A;  1R5G A;  4U6J A;  1YW9 A;  3TAV A;  4FLL A;  3MAT A;  4U6W A;  2GU6 A;  4U69 A;  1XGO A;  2GU7 A;  1YW8 A;  5CIK A;  5D6F A;  5CLS A;  4FLJ A;  4FO7 A;  4IKS A;  2GA2 A;  4IKR A;  5CE6 A;  2P98 A;  2GG8 A;  4RGZ 1;  5FCF A;  1WKM A;  2BWU A;  4R60 A;  1WL9 A;  2DFI A;  3BIQ A;  4HXX A;  1YW7 A;  3TB5 A;  1XGM A;  2BHD A;  2Q8K A;  4S2R P;  2GG3 A;  2GG0 A;  3IU7 A;  5E5B A;  2V6C A;  4U6Z A;  2BWY A;  1YJ3 A;  1MAT A;  3BIT A;  1R58 A;  4A6V A;  3MX6 A;  4FLK A;  2GGC A;  1BOA A;  2BN7 A;  1QXW A;  1QZY A;  4ZWO A;  1O0X A;  2EA2 A;  4U71 A;  2GG5 A;  2GU4 A;  4ZWP A;  2BWX A;  4IF7 A;  4U6E A;  1CHM A;  3PKD A;  2P99 A;  3PKA A;  3FMQ A;  2V3Y A;  1QXY A;  2IW2 A;  2V3Z A;  2ADU A;  1W2M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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