1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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molecule tags Hydrolase
source organism Mycobacterium tuberculosis
publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
molecule keywords Methionine aminopeptidase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
3PKCA 2GU7A 1YW9A 2EVMA 4A6VA 4ZWOA 2B3HA 2Q95A 4U69A 1YVMA 3PKAA 2IW2A 1O0XA 3BITA 3Q6DA 2GA2A 1XGNA 4S2RP 3MR1A 2EA2A 5CIKA 2Q8KA 4Z7MA 2GZ5A 4U75A 2P99A 3L24A 2EVCA 2ADUA 2EA4A 2GU5A 1QXZA 4PNCA 2B3KA 2BWXA 2G6PA 2Q94A 3BIQA 4U76A 1B59A 2GGCA 4U73A 3IU7A 2BB7A 2BWUA 1XGOA 4U1BA 2NQ6A 4U6CA 4ZWPA 2V6CA 4RZYA 4ZWUA 4JUQA 3S6BA 5D6FA 1R5GA 4U6ZA 1C27A 5CDEA 3PKDA 1XGSA 2ZSGA 4IDYA 3TB5A 4KM3A 3FMRA 4EGEA 1B6AA 1WL6A 4FLLA 1WKMA 1MATA 1C23A 4RZZA 3TAVA 2GU6A 1C22A 3CB5A 5CLSA 4IF7A 2BHDA 4FO8A 3PKBA 1BOAA 3IG4A 1YW8A 2BHAA 4FKCA 4ZNGA 1KP0A 4IPAA 4RGZ1 1M35A 3MATA 2GG9A 2B3LA 2EVOA 2V3XA 4HXXA 4OOKA 5FCHA 2BWTA 1W7VA 4IU6A 1XGMA 1KQ0A 2GG2A 2GG5A 3PKEA 1Y1NA 4IKSA 4IKTA 4U6WA 4A6WA 3IU9A 3IU8A 1JAWA 1CHMA 2BWWA 2OAZA 5JFRA 1N51A 2OKNA 1WL9A 2GG0A 4QR8A 4FLJA 1XNZA 2P98A 3FMQA 2V3YA 3RORA 4FLKA 1QXWA 4FLIA 2NQ7A 5D6EA 2BWVA 1C21A 2BWYA 4B28A 3CB6A 2BWSA 4S00A 3L7GA 2P9AA 2MATA 1WLRA 3MX6A 4U6EA 2GG7A 1R5HA 2BH3A 4PV4A 5CDVA 1R58A 4FUKA 1YW7A 2GTXA 4S2TP 1WY2A 1W2MA 4S01A 2Q92A 2DFIA 2HOWA 1YJ3A 3CTZA 4FO7A 1WBQA 4U71A 3D27A 1PV9A 1QXYA 4U6JA 5JI6A 1QZYA 2BHCA 4IECA 2GG3A 5CNXA 2Q96A 3FM3A 1WN1A 2GGBA 3BIPA 1C24A 3RVAA 1BN5A 1KQ9A 4IKRA 1A16A 2GU4A 5FCFA 4MATA 2V3ZA 4U70A 5JHUA 2Q93A 5CDLA 5E5BA 5CE6A 2GG8A 4R60A 2BHBA 4IKUA 2BN7A
chains in the Genus database with same CATH superfamily
3PKCA 2GU7A 1YW9A 2EVMA 4A6VA 4ZWOA 2B3HA 2Q95A 4U69A 1YVMA 3PKAA 2IW2A 1O0XA 3BITA 3Q6DA 2GA2A 1XGNA 4S2RP 3MR1A 2EA2A 5CIKA 2Q8KA 4Z7MA 2GZ5A 4U75A 2P99A 3L24A 2EVCA 2ADUA 2EA4A 2GU5A 1QXZA 4PNCA 2B3KA 2BWXA 2G6PA 2Q94A 3BIQA 4U76A 1B59A 2GGCA 4U73A 3IU7A 2BB7A 2BWUA 1XGOA 4U1BA 2NQ6A 4U6CA 4ZWPA 2V6CA 4RZYA 4ZWUA 4JUQA 3S6BA 5D6FA 1R5GA 4U6ZA 1C27A 5CDEA 3PKDA 1XGSA 2ZSGA 4IDYA 3TB5A 4KM3A 3FMRA 4EGEA 1B6AA 1WL6A 4FLLA 1WKMA 1MATA 1C23A 4RZZA 3TAVA 2GU6A 1C22A 3CB5A 5CLSA 4IF7A 2BHDA 4FO8A 3PKBA 1BOAA 3IG4A 1YW8A 2BHAA 4FKCA 4ZNGA 1KP0A 4IPAA 4RGZ1 1M35A 3MATA 2GG9A 2B3LA 2EVOA 2V3XA 4HXXA 4OOKA 5FCHA 2BWTA 1W7VA 4IU6A 1XGMA 1KQ0A 2GG2A 2GG5A 3PKEA 1Y1NA 4IKSA 4IKTA 4U6WA 4A6WA 3IU9A 3IU8A 1JAWA 1CHMA 2BWWA 2OAZA 5JFRA 1N51A 2OKNA 1WL9A 2GG0A 4QR8A 4FLJA 1XNZA 2P98A 3FMQA 2V3YA 3RORA 4FLKA 1QXWA 4FLIA 2NQ7A 5D6EA 2BWVA 1C21A 2BWYA 4B28A 3CB6A 2BWSA 4S00A 3L7GA 2P9AA 2MATA 1WLRA 3MX6A 4U6EA 2GG7A 1R5HA 2BH3A 4PV4A 5CDVA 1R58A 4FUKA 1YW7A 2GTXA 4S2TP 1WY2A 1W2MA 4S01A 2Q92A 2DFIA 2HOWA 1YJ3A 3CTZA 4FO7A 1WBQA 4U71A 3D27A 1PV9A 1QXYA 4U6JA 5JI6A 1QZYA 2BHCA 4IECA 2GG3A 5CNXA 2Q96A 3FM3A 1WN1A 2GGBA 3BIPA 1C24A 3RVAA 1BN5A 1KQ9A 4IKRA 1A16A 2GU4A 5FCFA 4MATA 2V3ZA 4U70A 5JHUA 2Q93A 5CDLA 5E5BA 5CE6A 2GG8A 4R60A 2BHBA 4IKUA 2BN7A
chains in the Genus database with same CATH topology
3PKCA 2GU7A 1YW9A 2EVMA 4A6VA 4ZWOA 2B3HA 2Q95A 4U69A 1YVMA 3PKAA 2IW2A 1O0XA 3BITA 3Q6DA 2GA2A 1XGNA 4S2RP 3MR1A 2EA2A 5CIKA 2Q8KA 4Z7MA 2GZ5A 4U75A 2P99A 3L24A 2EVCA 2ADUA 2EA4A 2GU5A 1QXZA 4PNCA 2B3KA 2BWXA 2G6PA 2Q94A 3BIQA 4U76A 1B59A 2GGCA 4U73A 3IU7A 2BB7A 2BWUA 1XGOA 4U1BA 2NQ6A 4U6CA 4ZWPA 2V6CA 4RZYA 4ZWUA 4JUQA 3S6BA 5D6FA 1R5GA 4U6ZA 1C27A 5CDEA 3PKDA 1XGSA 2ZSGA 4IDYA 3TB5A 4KM3A 3FMRA 4EGEA 1B6AA 1WL6A 4FLLA 1WKMA 1MATA 1C23A 4RZZA 3TAVA 2GU6A 1C22A 3CB5A 5CLSA 4IF7A 2BHDA 4FO8A 3PKBA 1BOAA 3IG4A 1YW8A 2BHAA 4FKCA 4ZNGA 1KP0A 4IPAA 4RGZ1 1M35A 3MATA 2GG9A 2B3LA 2EVOA 2V3XA 4HXXA 4OOKA 5FCHA 2BWTA 1W7VA 4IU6A 1XGMA 1KQ0A 2GG2A 2GG5A 3PKEA 1Y1NA 4IKSA 4IKTA 4U6WA 4A6WA 3IU9A 3IU8A 1JAWA 1CHMA 2BWWA 2OAZA 5JFRA 1N51A 2OKNA 1WL9A 2GG0A 4QR8A 4FLJA 1XNZA 2P98A 3FMQA 2V3YA 3RORA 4FLKA 1QXWA 4FLIA 2NQ7A 5D6EA 2BWVA 1C21A 2BWYA 4B28A 3CB6A 2BWSA 4S00A 3L7GA 2P9AA 2MATA 1WLRA 3MX6A 4U6EA 2GG7A 1R5HA 2BH3A 4PV4A 5CDVA 1R58A 4FUKA 1YW7A 2GTXA 4S2TP 1WY2A 1W2MA 4S01A 2Q92A 2DFIA 2HOWA 1YJ3A 3CTZA 4FO7A 1WBQA 4U71A 3D27A 1PV9A 1QXYA 4U6JA 5JI6A 1QZYA 2BHCA 4IECA 2GG3A 5CNXA 2Q96A 3FM3A 1WN1A 2GGBA 3BIPA 1C24A 3RVAA 1BN5A 1KQ9A 4IKRA 1A16A 2GU4A 5FCFA 4MATA 2V3ZA 4U70A 5JHUA 2Q93A 5CDLA 5E5BA 5CE6A 2GG8A 4R60A 2BHBA 4IKUA 2BN7A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 3PKC A;  2GU7 A;  1YW9 A;  2EVM A;  4A6V A;  4ZWO A;  2B3H A;  2Q95 A;  4U69 A;  1YVM A;  3PKA A;  2IW2 A;  1O0X A;  3BIT A;  3Q6D A;  2GA2 A;  1XGN A;  4S2R P;  3MR1 A;  2EA2 A;  5CIK A;  2Q8K A;  4Z7M A;  2GZ5 A;  4U75 A;  2P99 A;  3L24 A;  2EVC A;  2ADU A;  2EA4 A;  2GU5 A;  1QXZ A;  4PNC A;  2B3K A;  2BWX A;  2G6P A;  2Q94 A;  3BIQ A;  4U76 A;  1B59 A;  2GGC A;  4U73 A;  3IU7 A;  2BB7 A;  2BWU A;  1XGO A;  4U1B A;  2NQ6 A;  4U6C A;  4ZWP A;  2V6C A;  4RZY A;  4ZWU A;  4JUQ A;  3S6B A;  5D6F A;  1R5G A;  4U6Z A;  1C27 A;  5CDE A;  3PKD A;  1XGS A;  2ZSG A;  4IDY A;  3TB5 A;  4KM3 A;  3FMR A;  4EGE A;  1B6A A;  1WL6 A;  4FLL A;  1WKM A;  1MAT A;  1C23 A;  4RZZ A;  3TAV A;  2GU6 A;  1C22 A;  3CB5 A;  5CLS A;  4IF7 A;  2BHD A;  4FO8 A;  3PKB A;  1BOA A;  3IG4 A;  1YW8 A;  2BHA A;  4FKC A;  4ZNG A;  1KP0 A;  4IPA A;  4RGZ 1;  1M35 A;  3MAT A;  2GG9 A;  2B3L A;  2EVO A;  2V3X A;  4HXX A;  4OOK A;  5FCH A;  2BWT A;  1W7V A;  4IU6 A;  1XGM A;  1KQ0 A;  2GG2 A;  2GG5 A;  3PKE A;  1Y1N A;  4IKS A;  4IKT A;  4U6W A;  4A6W A;  3IU9 A;  3IU8 A;  1JAW A;  1CHM A;  2BWW A;  2OAZ A;  5JFR A;  1N51 A;  2OKN A;  1WL9 A;  2GG0 A;  4QR8 A;  4FLJ A;  1XNZ A;  2P98 A;  3FMQ A;  2V3Y A;  3ROR A;  4FLK A;  1QXW A;  4FLI A;  2NQ7 A;  5D6E A;  2BWV A;  1C21 A;  2BWY A;  4B28 A;  3CB6 A;  2BWS A;  4S00 A;  3L7G A;  2P9A A;  2MAT A;  1WLR A;  3MX6 A;  4U6E A;  2GG7 A;  1R5H A;  2BH3 A;  4PV4 A;  5CDV A;  1R58 A;  4FUK A;  1YW7 A;  2GTX A;  4S2T P;  1WY2 A;  1W2M A;  4S01 A;  2Q92 A;  2DFI A;  2HOW A;  1YJ3 A;  3CTZ A;  4FO7 A;  1WBQ A;  4U71 A;  3D27 A;  1PV9 A;  1QXY A;  4U6J A;  5JI6 A;  1QZY A;  2BHC A;  4IEC A;  2GG3 A;  5CNX A;  2Q96 A;  3FM3 A;  1WN1 A;  2GGB A;  3BIP A;  1C24 A;  3RVA A;  1BN5 A;  1KQ9 A;  4IKR A;  1A16 A;  2GU4 A;  5FCF A;  4MAT A;  2V3Z A;  4U70 A;  5JHU A;  2Q93 A;  5CDL A;  5E5B A;  5CE6 A;  2GG8 A;  4R60 A;  2BHB A;  4IKU A;  2BN7 A; 
#chains in the Genus database with same CATH topology
 3PKC A;  2GU7 A;  1YW9 A;  2EVM A;  4A6V A;  4ZWO A;  2B3H A;  2Q95 A;  4U69 A;  1YVM A;  3PKA A;  2IW2 A;  1O0X A;  3BIT A;  3Q6D A;  2GA2 A;  1XGN A;  4S2R P;  3MR1 A;  2EA2 A;  5CIK A;  2Q8K A;  4Z7M A;  2GZ5 A;  4U75 A;  2P99 A;  3L24 A;  2EVC A;  2ADU A;  2EA4 A;  2GU5 A;  1QXZ A;  4PNC A;  2B3K A;  2BWX A;  2G6P A;  2Q94 A;  3BIQ A;  4U76 A;  1B59 A;  2GGC A;  4U73 A;  3IU7 A;  2BB7 A;  2BWU A;  1XGO A;  4U1B A;  2NQ6 A;  4U6C A;  4ZWP A;  2V6C A;  4RZY A;  4ZWU A;  4JUQ A;  3S6B A;  5D6F A;  1R5G A;  4U6Z A;  1C27 A;  5CDE A;  3PKD A;  1XGS A;  2ZSG A;  4IDY A;  3TB5 A;  4KM3 A;  3FMR A;  4EGE A;  1B6A A;  1WL6 A;  4FLL A;  1WKM A;  1MAT A;  1C23 A;  4RZZ A;  3TAV A;  2GU6 A;  1C22 A;  3CB5 A;  5CLS A;  4IF7 A;  2BHD A;  4FO8 A;  3PKB A;  1BOA A;  3IG4 A;  1YW8 A;  2BHA A;  4FKC A;  4ZNG A;  1KP0 A;  4IPA A;  4RGZ 1;  1M35 A;  3MAT A;  2GG9 A;  2B3L A;  2EVO A;  2V3X A;  4HXX A;  4OOK A;  5FCH A;  2BWT A;  1W7V A;  4IU6 A;  1XGM A;  1KQ0 A;  2GG2 A;  2GG5 A;  3PKE A;  1Y1N A;  4IKS A;  4IKT A;  4U6W A;  4A6W A;  3IU9 A;  3IU8 A;  1JAW A;  1CHM A;  2BWW A;  2OAZ A;  5JFR A;  1N51 A;  2OKN A;  1WL9 A;  2GG0 A;  4QR8 A;  4FLJ A;  1XNZ A;  2P98 A;  3FMQ A;  2V3Y A;  3ROR A;  4FLK A;  1QXW A;  4FLI A;  2NQ7 A;  5D6E A;  2BWV A;  1C21 A;  2BWY A;  4B28 A;  3CB6 A;  2BWS A;  4S00 A;  3L7G A;  2P9A A;  2MAT A;  1WLR A;  3MX6 A;  4U6E A;  2GG7 A;  1R5H A;  2BH3 A;  4PV4 A;  5CDV A;  1R58 A;  4FUK A;  1YW7 A;  2GTX A;  4S2T P;  1WY2 A;  1W2M A;  4S01 A;  2Q92 A;  2DFI A;  2HOW A;  1YJ3 A;  3CTZ A;  4FO7 A;  1WBQ A;  4U71 A;  3D27 A;  1PV9 A;  1QXY A;  4U6J A;  5JI6 A;  1QZY A;  2BHC A;  4IEC A;  2GG3 A;  5CNX A;  2Q96 A;  3FM3 A;  1WN1 A;  2GGB A;  3BIP A;  1C24 A;  3RVA A;  1BN5 A;  1KQ9 A;  4IKR A;  1A16 A;  2GU4 A;  5FCF A;  4MAT A;  2V3Z A;  4U70 A;  5JHU A;  2Q93 A;  5CDL A;  5E5B A;  5CE6 A;  2GG8 A;  4R60 A;  2BHB A;  4IKU A;  2BN7 A; 
#chains in the Genus database with same CATH homology
 3PKC A;  2GU7 A;  1YW9 A;  2EVM A;  4A6V A;  4ZWO A;  2B3H A;  2Q95 A;  4U69 A;  1YVM A;  3PKA A;  2IW2 A;  1O0X A;  3BIT A;  3Q6D A;  2GA2 A;  1XGN A;  4S2R P;  3MR1 A;  2EA2 A;  5CIK A;  2Q8K A;  4Z7M A;  2GZ5 A;  4U75 A;  2P99 A;  3L24 A;  2EVC A;  2ADU A;  2EA4 A;  2GU5 A;  1QXZ A;  4PNC A;  2B3K A;  2BWX A;  2G6P A;  2Q94 A;  3BIQ A;  4U76 A;  1B59 A;  2GGC A;  4U73 A;  3IU7 A;  2BB7 A;  2BWU A;  1XGO A;  4U1B A;  2NQ6 A;  4U6C A;  4ZWP A;  2V6C A;  4RZY A;  4ZWU A;  4JUQ A;  3S6B A;  5D6F A;  1R5G A;  4U6Z A;  1C27 A;  5CDE A;  3PKD A;  1XGS A;  2ZSG A;  4IDY A;  3TB5 A;  4KM3 A;  3FMR A;  4EGE A;  1B6A A;  1WL6 A;  4FLL A;  1WKM A;  1MAT A;  1C23 A;  4RZZ A;  3TAV A;  2GU6 A;  1C22 A;  3CB5 A;  5CLS A;  4IF7 A;  2BHD A;  4FO8 A;  3PKB A;  1BOA A;  3IG4 A;  1YW8 A;  2BHA A;  4FKC A;  4ZNG A;  1KP0 A;  4IPA A;  4RGZ 1;  1M35 A;  3MAT A;  2GG9 A;  2B3L A;  2EVO A;  2V3X A;  4HXX A;  4OOK A;  5FCH A;  2BWT A;  1W7V A;  4IU6 A;  1XGM A;  1KQ0 A;  2GG2 A;  2GG5 A;  3PKE A;  1Y1N A;  4IKS A;  4IKT A;  4U6W A;  4A6W A;  3IU9 A;  3IU8 A;  1JAW A;  1CHM A;  2BWW A;  2OAZ A;  5JFR A;  1N51 A;  2OKN A;  1WL9 A;  2GG0 A;  4QR8 A;  4FLJ A;  1XNZ A;  2P98 A;  3FMQ A;  2V3Y A;  3ROR A;  4FLK A;  1QXW A;  4FLI A;  2NQ7 A;  5D6E A;  2BWV A;  1C21 A;  2BWY A;  4B28 A;  3CB6 A;  2BWS A;  4S00 A;  3L7G A;  2P9A A;  2MAT A;  1WLR A;  3MX6 A;  4U6E A;  2GG7 A;  1R5H A;  2BH3 A;  4PV4 A;  5CDV A;  1R58 A;  4FUK A;  1YW7 A;  2GTX A;  4S2T P;  1WY2 A;  1W2M A;  4S01 A;  2Q92 A;  2DFI A;  2HOW A;  1YJ3 A;  3CTZ A;  4FO7 A;  1WBQ A;  4U71 A;  3D27 A;  1PV9 A;  1QXY A;  4U6J A;  5JI6 A;  1QZY A;  2BHC A;  4IEC A;  2GG3 A;  5CNX A;  2Q96 A;  3FM3 A;  1WN1 A;  2GGB A;  3BIP A;  1C24 A;  3RVA A;  1BN5 A;  1KQ9 A;  4IKR A;  1A16 A;  2GU4 A;  5FCF A;  4MAT A;  2V3Z A;  4U70 A;  5JHU A;  2Q93 A;  5CDL A;  5E5B A;  5CE6 A;  2GG8 A;  4R60 A;  2BHB A;  4IKU A;  2BN7 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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