1YJ3A

Crystal structure analysis of product bound methionine aminopeptidase type 1c from mycobacterium tuberculosis
Total Genus 87
Loading diagram...

The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
87
sequence length
282
structure length
282
Chain Sequence
RTALSPGVLSPTRPVPNWIARPEYVGKPAAQEGSEPWVQTPEVIEKMRVAGRIAAGALAEAGKAVAPGVTTDELDRIAHEYLVDNGAYPSTLGYKGFPKSCCTSLNEVICHGIPDSTVITDGDIVNIDVTAYIGGVHGDTNATFPAGDVADEHRLLVDRTREATMRAINTVKPGRALSVIGRVIESYANRFGYNVVRDFTGHGIGTTFHNGLVVLHYDQPAVETIMQPGMTFTIEPMINLGALDYEIWDDGWTVVTKDRKWTAQFEHTLLVTDTGVEILTCL
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
{{ tooltip.sname }} connected with {{ tooltip.tname }} : {{qFormat(tooltip.svalue) }}
publication title Identification of an SH3-binding motif in a new class of methionine aminopeptidases from Mycobacterium tuberculosis suggests a mode of interaction with the ribosome.
pubmed doi rcsb
molecule tags Hydrolase
source organism Mycobacterium tuberculosis
molecule keywords Methionine aminopeptidase
total genus 87
structure length 282
sequence length 282
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2005-01-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1yj3A01
2GG2A 2Q94A 3CB6A 4RZYA 2GTXA 3IU8A 3FMQA 4U71A 1M35A 2GU4A 2P98A 1R5HA 2MATA 2EVMA 2DFIA 3PKEA 3MX6A 1QXWA 1KQ0A 4RZZA 1JAWA 2EA4A 5CNXA 2BWSA 4FLLA 3L7GA 2EVOA 1C27A 4IKSA 4S2TP 1B59A 1QXYA 2ADUA 4FUKA 4OOKA 4ZWUA 2BHBA 4U76A 2Q92A 3FM3A 1N51A 5JFRA 3TAVA 2GGBA 1C23A 1WLRA 4ZWPA 2EA2A 3IG4A 3CTZA 2BWYA 2Q96A 5CDEA 4FKCA 4U6ZA 2GG0A 4U6JA 3PKBA 1BN5A 2B3KA 2V3ZA 3BITA 3FMRA 2Q8KA 3Q6DA 3BIQA 2IW2A 4ZNGA 2BWWA 5JHUA 2BWXA 1KP0A 2BHCA 3MR1A 4A6WA 2GU7A 2BB7A 1XGOA 1YW8A 1YW9A 4U6WA 4U73A 1R5GA 4IF7A 4IU6A 4U1BA 4U6EA 2Q93A 4FLJA 4B28A 1WL6A 1WY2A 1W7VA 2EVCA 4U75A 1A16A 2B3LA 2NQ6A 1XGNA 2NQ7A 2P99A 3CB5A 4PNCA 4FO7A 4S2RP 1MATA 2BHDA 2GU6A 4IPAA 3PKCA 3L24A 2G6PA 4S00A 1CHMA 5CE6A 4S01A 2GG8A 2BWUA 4A6VA 2V3XA 3IU7A 1R58A 4FLIA 4R60A 1YVMA 2GA2A 1PV9A 3PKAA 5D6FA 1C24A 3RORA 2BH3A 2OAZA 2OKNA 4FLKA 1WBQA 4RGZ1 4QR8A 1XGSA 5FCHA 4KM3A 1QZYA 4EGEA 2P9AA 4U6CA 1C21A 2V3YA 3PKDA 4HXXA 2GG9A 4IDYA 4Z7MA 1BOAA 2BWVA 1W2MA 1XNZA 4JUQA 2BHAA 2GG3A 5CDLA 5CDVA 1WL9A 4IKTA 4ZWOA 4U69A 1QXZA 1XGMA 4IKRA 2GG7A 5E5BA 1WN1A 5CLSA 4PV4A 3S6BA 3RVAA 4U70A 2BN7A 2GZ5A 3MATA 2BWTA 2GGCA 2HOWA 1B6AA 2GG5A 3BIPA 3IU9A 5D6EA 4MATA 2ZSGA 2GU5A 1C22A 3TB5A 1WKMA 5JI6A 2V6CA 5FCFA 5CIKA 1Y1NA 3D27A 2Q95A 1YW7A 4FO8A 1O0XA 4IKUA 2B3HA 1KQ9A 4IECA 1YJ3A
chains in the Genus database with same CATH superfamily
2GG2A 2Q94A 3CB6A 4RZYA 2GTXA 3IU8A 3FMQA 4U71A 1M35A 2GU4A 2P98A 1R5HA 2MATA 2EVMA 2DFIA 3PKEA 3MX6A 1QXWA 1KQ0A 4RZZA 1JAWA 2EA4A 5CNXA 2BWSA 4FLLA 3L7GA 2EVOA 1C27A 4IKSA 4S2TP 1B59A 1QXYA 2ADUA 4FUKA 4OOKA 4ZWUA 2BHBA 4U76A 2Q92A 3FM3A 1N51A 5JFRA 3TAVA 2GGBA 1C23A 1WLRA 4ZWPA 2EA2A 3IG4A 3CTZA 2BWYA 2Q96A 5CDEA 4FKCA 4U6ZA 2GG0A 4U6JA 3PKBA 1BN5A 2B3KA 2V3ZA 3BITA 3FMRA 2Q8KA 3Q6DA 3BIQA 2IW2A 4ZNGA 2BWWA 5JHUA 2BWXA 1KP0A 2BHCA 3MR1A 4A6WA 2GU7A 2BB7A 1XGOA 1YW8A 1YW9A 4U6WA 4U73A 1R5GA 4IF7A 4IU6A 4U1BA 4U6EA 2Q93A 4FLJA 4B28A 1WL6A 1WY2A 1W7VA 2EVCA 4U75A 1A16A 2B3LA 2NQ6A 1XGNA 2NQ7A 2P99A 3CB5A 4PNCA 4FO7A 4S2RP 1MATA 2BHDA 2GU6A 4IPAA 3PKCA 3L24A 2G6PA 4S00A 1CHMA 5CE6A 4S01A 2GG8A 2BWUA 4A6VA 2V3XA 3IU7A 1R58A 4FLIA 4R60A 1YVMA 2GA2A 1PV9A 3PKAA 5D6FA 1C24A 3RORA 2BH3A 2OAZA 2OKNA 4FLKA 1WBQA 4RGZ1 4QR8A 1XGSA 5FCHA 4KM3A 1QZYA 4EGEA 2P9AA 4U6CA 1C21A 2V3YA 3PKDA 4HXXA 2GG9A 4IDYA 4Z7MA 1BOAA 2BWVA 1W2MA 1XNZA 4JUQA 2BHAA 2GG3A 5CDLA 5CDVA 1WL9A 4IKTA 4ZWOA 4U69A 1QXZA 1XGMA 4IKRA 2GG7A 5E5BA 1WN1A 5CLSA 4PV4A 3S6BA 3RVAA 4U70A 2BN7A 2GZ5A 3MATA 2BWTA 2GGCA 2HOWA 1B6AA 2GG5A 3BIPA 3IU9A 5D6EA 4MATA 2ZSGA 2GU5A 1C22A 3TB5A 1WKMA 5JI6A 2V6CA 5FCFA 5CIKA 1Y1NA 3D27A 2Q95A 1YW7A 4FO8A 1O0XA 4IKUA 2B3HA 1KQ9A 4IECA 1YJ3A
chains in the Genus database with same CATH topology
2GG2A 2Q94A 3CB6A 4RZYA 2GTXA 3IU8A 3FMQA 4U71A 1M35A 2GU4A 2P98A 1R5HA 2MATA 2EVMA 2DFIA 3PKEA 3MX6A 1QXWA 1KQ0A 4RZZA 1JAWA 2EA4A 5CNXA 2BWSA 4FLLA 3L7GA 2EVOA 1C27A 4IKSA 4S2TP 1B59A 1QXYA 2ADUA 4FUKA 4OOKA 4ZWUA 2BHBA 4U76A 2Q92A 3FM3A 1N51A 5JFRA 3TAVA 2GGBA 1C23A 1WLRA 4ZWPA 2EA2A 3IG4A 3CTZA 2BWYA 2Q96A 5CDEA 4FKCA 4U6ZA 2GG0A 4U6JA 3PKBA 1BN5A 2B3KA 2V3ZA 3BITA 3FMRA 2Q8KA 3Q6DA 3BIQA 2IW2A 4ZNGA 2BWWA 5JHUA 2BWXA 1KP0A 2BHCA 3MR1A 4A6WA 2GU7A 2BB7A 1XGOA 1YW8A 1YW9A 4U6WA 4U73A 1R5GA 4IF7A 4IU6A 4U1BA 4U6EA 2Q93A 4FLJA 4B28A 1WL6A 1WY2A 1W7VA 2EVCA 4U75A 1A16A 2B3LA 2NQ6A 1XGNA 2NQ7A 2P99A 3CB5A 4PNCA 4FO7A 4S2RP 1MATA 2BHDA 2GU6A 4IPAA 3PKCA 3L24A 2G6PA 4S00A 1CHMA 5CE6A 4S01A 2GG8A 2BWUA 4A6VA 2V3XA 3IU7A 1R58A 4FLIA 4R60A 1YVMA 2GA2A 1PV9A 3PKAA 5D6FA 1C24A 3RORA 2BH3A 2OAZA 2OKNA 4FLKA 1WBQA 4RGZ1 4QR8A 1XGSA 5FCHA 4KM3A 1QZYA 4EGEA 2P9AA 4U6CA 1C21A 2V3YA 3PKDA 4HXXA 2GG9A 4IDYA 4Z7MA 1BOAA 2BWVA 1W2MA 1XNZA 4JUQA 2BHAA 2GG3A 5CDLA 5CDVA 1WL9A 4IKTA 4ZWOA 4U69A 1QXZA 1XGMA 4IKRA 2GG7A 5E5BA 1WN1A 5CLSA 4PV4A 3S6BA 3RVAA 4U70A 2BN7A 2GZ5A 3MATA 2BWTA 2GGCA 2HOWA 1B6AA 2GG5A 3BIPA 3IU9A 5D6EA 4MATA 2ZSGA 2GU5A 1C22A 3TB5A 1WKMA 5JI6A 2V6CA 5FCFA 5CIKA 1Y1NA 3D27A 2Q95A 1YW7A 4FO8A 1O0XA 4IKUA 2B3HA 1KQ9A 4IECA 1YJ3A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2GG2 A;  2Q94 A;  3CB6 A;  4RZY A;  2GTX A;  3IU8 A;  3FMQ A;  4U71 A;  1M35 A;  2GU4 A;  2P98 A;  1R5H A;  2MAT A;  2EVM A;  2DFI A;  3PKE A;  3MX6 A;  1QXW A;  1KQ0 A;  4RZZ A;  1JAW A;  2EA4 A;  5CNX A;  2BWS A;  4FLL A;  3L7G A;  2EVO A;  1C27 A;  4IKS A;  4S2T P;  1B59 A;  1QXY A;  2ADU A;  4FUK A;  4OOK A;  4ZWU A;  2BHB A;  4U76 A;  2Q92 A;  3FM3 A;  1N51 A;  5JFR A;  3TAV A;  2GGB A;  1C23 A;  1WLR A;  4ZWP A;  2EA2 A;  3IG4 A;  3CTZ A;  2BWY A;  2Q96 A;  5CDE A;  4FKC A;  4U6Z A;  2GG0 A;  4U6J A;  3PKB A;  1BN5 A;  2B3K A;  2V3Z A;  3BIT A;  3FMR A;  2Q8K A;  3Q6D A;  3BIQ A;  2IW2 A;  4ZNG A;  2BWW A;  5JHU A;  2BWX A;  1KP0 A;  2BHC A;  3MR1 A;  4A6W A;  2GU7 A;  2BB7 A;  1XGO A;  1YW8 A;  1YW9 A;  4U6W A;  4U73 A;  1R5G A;  4IF7 A;  4IU6 A;  4U1B A;  4U6E A;  2Q93 A;  4FLJ A;  4B28 A;  1WL6 A;  1WY2 A;  1W7V A;  2EVC A;  4U75 A;  1A16 A;  2B3L A;  2NQ6 A;  1XGN A;  2NQ7 A;  2P99 A;  3CB5 A;  4PNC A;  4FO7 A;  4S2R P;  1MAT A;  2BHD A;  2GU6 A;  4IPA A;  3PKC A;  3L24 A;  2G6P A;  4S00 A;  1CHM A;  5CE6 A;  4S01 A;  2GG8 A;  2BWU A;  4A6V A;  2V3X A;  3IU7 A;  1R58 A;  4FLI A;  4R60 A;  1YVM A;  2GA2 A;  1PV9 A;  3PKA A;  5D6F A;  1C24 A;  3ROR A;  2BH3 A;  2OAZ A;  2OKN A;  4FLK A;  1WBQ A;  4RGZ 1;  4QR8 A;  1XGS A;  5FCH A;  4KM3 A;  1QZY A;  4EGE A;  2P9A A;  4U6C A;  1C21 A;  2V3Y A;  3PKD A;  4HXX A;  2GG9 A;  4IDY A;  4Z7M A;  1BOA A;  2BWV A;  1W2M A;  1XNZ A;  4JUQ A;  2BHA A;  2GG3 A;  5CDL A;  5CDV A;  1WL9 A;  4IKT A;  4ZWO A;  4U69 A;  1QXZ A;  1XGM A;  4IKR A;  2GG7 A;  5E5B A;  1WN1 A;  5CLS A;  4PV4 A;  3S6B A;  3RVA A;  4U70 A;  2BN7 A;  2GZ5 A;  3MAT A;  2BWT A;  2GGC A;  2HOW A;  1B6A A;  2GG5 A;  3BIP A;  3IU9 A;  5D6E A;  4MAT A;  2ZSG A;  2GU5 A;  1C22 A;  3TB5 A;  1WKM A;  5JI6 A;  2V6C A;  5FCF A;  5CIK A;  1Y1N A;  3D27 A;  2Q95 A;  1YW7 A;  4FO8 A;  1O0X A;  4IKU A;  2B3H A;  1KQ9 A;  4IEC A;  1YJ3 A; 
#chains in the Genus database with same CATH topology
 2GG2 A;  2Q94 A;  3CB6 A;  4RZY A;  2GTX A;  3IU8 A;  3FMQ A;  4U71 A;  1M35 A;  2GU4 A;  2P98 A;  1R5H A;  2MAT A;  2EVM A;  2DFI A;  3PKE A;  3MX6 A;  1QXW A;  1KQ0 A;  4RZZ A;  1JAW A;  2EA4 A;  5CNX A;  2BWS A;  4FLL A;  3L7G A;  2EVO A;  1C27 A;  4IKS A;  4S2T P;  1B59 A;  1QXY A;  2ADU A;  4FUK A;  4OOK A;  4ZWU A;  2BHB A;  4U76 A;  2Q92 A;  3FM3 A;  1N51 A;  5JFR A;  3TAV A;  2GGB A;  1C23 A;  1WLR A;  4ZWP A;  2EA2 A;  3IG4 A;  3CTZ A;  2BWY A;  2Q96 A;  5CDE A;  4FKC A;  4U6Z A;  2GG0 A;  4U6J A;  3PKB A;  1BN5 A;  2B3K A;  2V3Z A;  3BIT A;  3FMR A;  2Q8K A;  3Q6D A;  3BIQ A;  2IW2 A;  4ZNG A;  2BWW A;  5JHU A;  2BWX A;  1KP0 A;  2BHC A;  3MR1 A;  4A6W A;  2GU7 A;  2BB7 A;  1XGO A;  1YW8 A;  1YW9 A;  4U6W A;  4U73 A;  1R5G A;  4IF7 A;  4IU6 A;  4U1B A;  4U6E A;  2Q93 A;  4FLJ A;  4B28 A;  1WL6 A;  1WY2 A;  1W7V A;  2EVC A;  4U75 A;  1A16 A;  2B3L A;  2NQ6 A;  1XGN A;  2NQ7 A;  2P99 A;  3CB5 A;  4PNC A;  4FO7 A;  4S2R P;  1MAT A;  2BHD A;  2GU6 A;  4IPA A;  3PKC A;  3L24 A;  2G6P A;  4S00 A;  1CHM A;  5CE6 A;  4S01 A;  2GG8 A;  2BWU A;  4A6V A;  2V3X A;  3IU7 A;  1R58 A;  4FLI A;  4R60 A;  1YVM A;  2GA2 A;  1PV9 A;  3PKA A;  5D6F A;  1C24 A;  3ROR A;  2BH3 A;  2OAZ A;  2OKN A;  4FLK A;  1WBQ A;  4RGZ 1;  4QR8 A;  1XGS A;  5FCH A;  4KM3 A;  1QZY A;  4EGE A;  2P9A A;  4U6C A;  1C21 A;  2V3Y A;  3PKD A;  4HXX A;  2GG9 A;  4IDY A;  4Z7M A;  1BOA A;  2BWV A;  1W2M A;  1XNZ A;  4JUQ A;  2BHA A;  2GG3 A;  5CDL A;  5CDV A;  1WL9 A;  4IKT A;  4ZWO A;  4U69 A;  1QXZ A;  1XGM A;  4IKR A;  2GG7 A;  5E5B A;  1WN1 A;  5CLS A;  4PV4 A;  3S6B A;  3RVA A;  4U70 A;  2BN7 A;  2GZ5 A;  3MAT A;  2BWT A;  2GGC A;  2HOW A;  1B6A A;  2GG5 A;  3BIP A;  3IU9 A;  5D6E A;  4MAT A;  2ZSG A;  2GU5 A;  1C22 A;  3TB5 A;  1WKM A;  5JI6 A;  2V6C A;  5FCF A;  5CIK A;  1Y1N A;  3D27 A;  2Q95 A;  1YW7 A;  4FO8 A;  1O0X A;  4IKU A;  2B3H A;  1KQ9 A;  4IEC A;  1YJ3 A; 
#chains in the Genus database with same CATH homology
 2GG2 A;  2Q94 A;  3CB6 A;  4RZY A;  2GTX A;  3IU8 A;  3FMQ A;  4U71 A;  1M35 A;  2GU4 A;  2P98 A;  1R5H A;  2MAT A;  2EVM A;  2DFI A;  3PKE A;  3MX6 A;  1QXW A;  1KQ0 A;  4RZZ A;  1JAW A;  2EA4 A;  5CNX A;  2BWS A;  4FLL A;  3L7G A;  2EVO A;  1C27 A;  4IKS A;  4S2T P;  1B59 A;  1QXY A;  2ADU A;  4FUK A;  4OOK A;  4ZWU A;  2BHB A;  4U76 A;  2Q92 A;  3FM3 A;  1N51 A;  5JFR A;  3TAV A;  2GGB A;  1C23 A;  1WLR A;  4ZWP A;  2EA2 A;  3IG4 A;  3CTZ A;  2BWY A;  2Q96 A;  5CDE A;  4FKC A;  4U6Z A;  2GG0 A;  4U6J A;  3PKB A;  1BN5 A;  2B3K A;  2V3Z A;  3BIT A;  3FMR A;  2Q8K A;  3Q6D A;  3BIQ A;  2IW2 A;  4ZNG A;  2BWW A;  5JHU A;  2BWX A;  1KP0 A;  2BHC A;  3MR1 A;  4A6W A;  2GU7 A;  2BB7 A;  1XGO A;  1YW8 A;  1YW9 A;  4U6W A;  4U73 A;  1R5G A;  4IF7 A;  4IU6 A;  4U1B A;  4U6E A;  2Q93 A;  4FLJ A;  4B28 A;  1WL6 A;  1WY2 A;  1W7V A;  2EVC A;  4U75 A;  1A16 A;  2B3L A;  2NQ6 A;  1XGN A;  2NQ7 A;  2P99 A;  3CB5 A;  4PNC A;  4FO7 A;  4S2R P;  1MAT A;  2BHD A;  2GU6 A;  4IPA A;  3PKC A;  3L24 A;  2G6P A;  4S00 A;  1CHM A;  5CE6 A;  4S01 A;  2GG8 A;  2BWU A;  4A6V A;  2V3X A;  3IU7 A;  1R58 A;  4FLI A;  4R60 A;  1YVM A;  2GA2 A;  1PV9 A;  3PKA A;  5D6F A;  1C24 A;  3ROR A;  2BH3 A;  2OAZ A;  2OKN A;  4FLK A;  1WBQ A;  4RGZ 1;  4QR8 A;  1XGS A;  5FCH A;  4KM3 A;  1QZY A;  4EGE A;  2P9A A;  4U6C A;  1C21 A;  2V3Y A;  3PKD A;  4HXX A;  2GG9 A;  4IDY A;  4Z7M A;  1BOA A;  2BWV A;  1W2M A;  1XNZ A;  4JUQ A;  2BHA A;  2GG3 A;  5CDL A;  5CDV A;  1WL9 A;  4IKT A;  4ZWO A;  4U69 A;  1QXZ A;  1XGM A;  4IKR A;  2GG7 A;  5E5B A;  1WN1 A;  5CLS A;  4PV4 A;  3S6B A;  3RVA A;  4U70 A;  2BN7 A;  2GZ5 A;  3MAT A;  2BWT A;  2GGC A;  2HOW A;  1B6A A;  2GG5 A;  3BIP A;  3IU9 A;  5D6E A;  4MAT A;  2ZSG A;  2GU5 A;  1C22 A;  3TB5 A;  1WKM A;  5JI6 A;  2V6C A;  5FCF A;  5CIK A;  1Y1N A;  3D27 A;  2Q95 A;  1YW7 A;  4FO8 A;  1O0X A;  4IKU A;  2B3H A;  1KQ9 A;  4IEC A;  1YJ3 A; 
...loading similar chains, please wait...
similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
...loading similar chains, please wait...
#similar chains, but unknotted
...loading similar chains, please wait...
#similar chains in the pdb database (?% sequence similarity)
...loading similar chains, please wait...