1C21A

E. coli methionine aminopeptidase: methionine complex
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
Loading diagram...

The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 88
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c21A00
1N51A 2BWWA 3FMRA 1C24A 4ZNGA 5CDEA 2GG0A 1WBQA 4B28A 3BITA 3L24A 2NQ7A 2HOWA 4RZYA 1XGOA 3CB6A 2BHCA 2BWXA 4U73A 4U75A 1QXZA 1MATA 2GG7A 4U6WA 3L7GA 2V3YA 4OOKA 2MATA 3PKAA 3PKEA 4EGEA 1WY2A 4FLIA 4U6CA 2Q93A 4PNCA 2P9AA 2GG3A 3FM3A 2GU4A 3IG4A 2B3KA 3TB5A 2P99A 4S00A 1W2MA 1KP0A 4ZWPA 4FUKA 2G6PA 5E5BA 4KM3A 3CB5A 2BHBA 2BWVA 2GG2A 4U70A 3CTZA 1B59A 1C27A 4IKUA 1YW7A 1R5HA 3BIQA 4JUQA 2BWTA 4A6VA 2Q95A 4FLKA 1C23A 1YW9A 5CLSA 4RZZA 2DFIA 2V6CA 1WKMA 1WN1A 3FMQA 4IKTA 2Q8KA 4FLJA 2Q96A 5FCFA 5CNXA 2GTXA 2EVOA 2GU7A 4QR8A 2ZSGA 1A16A 2EA2A 3IU8A 1R58A 1QZYA 2IW2A 1JAWA 1W7VA 3D27A 4RGZ1 1QXWA 4U76A 2ADUA 5CDLA 1O0XA 2BWSA 2GU6A 2P98A 1BOAA 3IU7A 4U71A 1M35A 1BN5A 2EA4A 5JI6A 4FKCA 1R5GA 4IECA 2GA2A 5CE6A 2Q94A 4R60A 4IKSA 4U1BA 4U6JA 4ZWOA 4Z7MA 4U69A 3BIPA 3MX6A 2V3ZA 3RORA 1PV9A 2EVMA 4HXXA 4MATA 1C22A 2GGCA 2GU5A 4FLLA 5JFRA 1YJ3A 1QXYA 2Q92A 2GZ5A 4IU6A 5CDVA 2B3LA 2OKNA 3Q6DA 3TAVA 5CIKA 4S01A 4S2TP 1YVMA 2BHDA 4IPAA 2GG9A 5D6FA 1B6AA 2BWUA 4IKRA 2BB7A 2OAZA 1WLRA 1Y1NA 2BWYA 3RVAA 2NQ6A 4U6EA 1XGSA 3S6BA 2BN7A 3PKCA 1C21A 1KQ9A 3MR1A 4IF7A 4FO7A 2EVCA 3MATA 4PV4A 5D6EA 1CHMA 1KQ0A 3IU9A 1XNZA 1YW8A 1WL6A 3PKBA 4ZWUA 1XGMA 1XGNA 2GGBA 2V3XA 2BHAA 4FO8A 4S2RP 4IDYA 2GG5A 3PKDA 1WL9A 4U6ZA 4A6WA 5JHUA 2BH3A 2B3HA 5FCHA 2GG8A
chains in the Genus database with same CATH superfamily
1N51A 2BWWA 3FMRA 1C24A 4ZNGA 5CDEA 2GG0A 1WBQA 4B28A 3BITA 3L24A 2NQ7A 2HOWA 4RZYA 1XGOA 3CB6A 2BHCA 2BWXA 4U73A 4U75A 1QXZA 1MATA 2GG7A 4U6WA 3L7GA 2V3YA 4OOKA 2MATA 3PKAA 3PKEA 4EGEA 1WY2A 4FLIA 4U6CA 2Q93A 4PNCA 2P9AA 2GG3A 3FM3A 2GU4A 3IG4A 2B3KA 3TB5A 2P99A 4S00A 1W2MA 1KP0A 4ZWPA 4FUKA 2G6PA 5E5BA 4KM3A 3CB5A 2BHBA 2BWVA 2GG2A 4U70A 3CTZA 1B59A 1C27A 4IKUA 1YW7A 1R5HA 3BIQA 4JUQA 2BWTA 4A6VA 2Q95A 4FLKA 1C23A 1YW9A 5CLSA 4RZZA 2DFIA 2V6CA 1WKMA 1WN1A 3FMQA 4IKTA 2Q8KA 4FLJA 2Q96A 5FCFA 5CNXA 2GTXA 2EVOA 2GU7A 4QR8A 2ZSGA 1A16A 2EA2A 3IU8A 1R58A 1QZYA 2IW2A 1JAWA 1W7VA 3D27A 4RGZ1 1QXWA 4U76A 2ADUA 5CDLA 1O0XA 2BWSA 2GU6A 2P98A 1BOAA 3IU7A 4U71A 1M35A 1BN5A 2EA4A 5JI6A 4FKCA 1R5GA 4IECA 2GA2A 5CE6A 2Q94A 4R60A 4IKSA 4U1BA 4U6JA 4ZWOA 4Z7MA 4U69A 3BIPA 3MX6A 2V3ZA 3RORA 1PV9A 2EVMA 4HXXA 4MATA 1C22A 2GGCA 2GU5A 4FLLA 5JFRA 1YJ3A 1QXYA 2Q92A 2GZ5A 4IU6A 5CDVA 2B3LA 2OKNA 3Q6DA 3TAVA 5CIKA 4S01A 4S2TP 1YVMA 2BHDA 4IPAA 2GG9A 5D6FA 1B6AA 2BWUA 4IKRA 2BB7A 2OAZA 1WLRA 1Y1NA 2BWYA 3RVAA 2NQ6A 4U6EA 1XGSA 3S6BA 2BN7A 3PKCA 1C21A 1KQ9A 3MR1A 4IF7A 4FO7A 2EVCA 3MATA 4PV4A 5D6EA 1CHMA 1KQ0A 3IU9A 1XNZA 1YW8A 1WL6A 3PKBA 4ZWUA 1XGMA 1XGNA 2GGBA 2V3XA 2BHAA 4FO8A 4S2RP 4IDYA 2GG5A 3PKDA 1WL9A 4U6ZA 4A6WA 5JHUA 2BH3A 2B3HA 5FCHA 2GG8A
chains in the Genus database with same CATH topology
1N51A 2BWWA 3FMRA 1C24A 4ZNGA 5CDEA 2GG0A 1WBQA 4B28A 3BITA 3L24A 2NQ7A 2HOWA 4RZYA 1XGOA 3CB6A 2BHCA 2BWXA 4U73A 4U75A 1QXZA 1MATA 2GG7A 4U6WA 3L7GA 2V3YA 4OOKA 2MATA 3PKAA 3PKEA 4EGEA 1WY2A 4FLIA 4U6CA 2Q93A 4PNCA 2P9AA 2GG3A 3FM3A 2GU4A 3IG4A 2B3KA 3TB5A 2P99A 4S00A 1W2MA 1KP0A 4ZWPA 4FUKA 2G6PA 5E5BA 4KM3A 3CB5A 2BHBA 2BWVA 2GG2A 4U70A 3CTZA 1B59A 1C27A 4IKUA 1YW7A 1R5HA 3BIQA 4JUQA 2BWTA 4A6VA 2Q95A 4FLKA 1C23A 1YW9A 5CLSA 4RZZA 2DFIA 2V6CA 1WKMA 1WN1A 3FMQA 4IKTA 2Q8KA 4FLJA 2Q96A 5FCFA 5CNXA 2GTXA 2EVOA 2GU7A 4QR8A 2ZSGA 1A16A 2EA2A 3IU8A 1R58A 1QZYA 2IW2A 1JAWA 1W7VA 3D27A 4RGZ1 1QXWA 4U76A 2ADUA 5CDLA 1O0XA 2BWSA 2GU6A 2P98A 1BOAA 3IU7A 4U71A 1M35A 1BN5A 2EA4A 5JI6A 4FKCA 1R5GA 4IECA 2GA2A 5CE6A 2Q94A 4R60A 4IKSA 4U1BA 4U6JA 4ZWOA 4Z7MA 4U69A 3BIPA 3MX6A 2V3ZA 3RORA 1PV9A 2EVMA 4HXXA 4MATA 1C22A 2GGCA 2GU5A 4FLLA 5JFRA 1YJ3A 1QXYA 2Q92A 2GZ5A 4IU6A 5CDVA 2B3LA 2OKNA 3Q6DA 3TAVA 5CIKA 4S01A 4S2TP 1YVMA 2BHDA 4IPAA 2GG9A 5D6FA 1B6AA 2BWUA 4IKRA 2BB7A 2OAZA 1WLRA 1Y1NA 2BWYA 3RVAA 2NQ6A 4U6EA 1XGSA 3S6BA 2BN7A 3PKCA 1C21A 1KQ9A 3MR1A 4IF7A 4FO7A 2EVCA 3MATA 4PV4A 5D6EA 1CHMA 1KQ0A 3IU9A 1XNZA 1YW8A 1WL6A 3PKBA 4ZWUA 1XGMA 1XGNA 2GGBA 2V3XA 2BHAA 4FO8A 4S2RP 4IDYA 2GG5A 3PKDA 1WL9A 4U6ZA 4A6WA 5JHUA 2BH3A 2B3HA 5FCHA 2GG8A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 1N51 A;  2BWW A;  3FMR A;  1C24 A;  4ZNG A;  5CDE A;  2GG0 A;  1WBQ A;  4B28 A;  3BIT A;  3L24 A;  2NQ7 A;  2HOW A;  4RZY A;  1XGO A;  3CB6 A;  2BHC A;  2BWX A;  4U73 A;  4U75 A;  1QXZ A;  1MAT A;  2GG7 A;  4U6W A;  3L7G A;  2V3Y A;  4OOK A;  2MAT A;  3PKA A;  3PKE A;  4EGE A;  1WY2 A;  4FLI A;  4U6C A;  2Q93 A;  4PNC A;  2P9A A;  2GG3 A;  3FM3 A;  2GU4 A;  3IG4 A;  2B3K A;  3TB5 A;  2P99 A;  4S00 A;  1W2M A;  1KP0 A;  4ZWP A;  4FUK A;  2G6P A;  5E5B A;  4KM3 A;  3CB5 A;  2BHB A;  2BWV A;  2GG2 A;  4U70 A;  3CTZ A;  1B59 A;  1C27 A;  4IKU A;  1YW7 A;  1R5H A;  3BIQ A;  4JUQ A;  2BWT A;  4A6V A;  2Q95 A;  4FLK A;  1C23 A;  1YW9 A;  5CLS A;  4RZZ A;  2DFI A;  2V6C A;  1WKM A;  1WN1 A;  3FMQ A;  4IKT A;  2Q8K A;  4FLJ A;  2Q96 A;  5FCF A;  5CNX A;  2GTX A;  2EVO A;  2GU7 A;  4QR8 A;  2ZSG A;  1A16 A;  2EA2 A;  3IU8 A;  1R58 A;  1QZY A;  2IW2 A;  1JAW A;  1W7V A;  3D27 A;  4RGZ 1;  1QXW A;  4U76 A;  2ADU A;  5CDL A;  1O0X A;  2BWS A;  2GU6 A;  2P98 A;  1BOA A;  3IU7 A;  4U71 A;  1M35 A;  1BN5 A;  2EA4 A;  5JI6 A;  4FKC A;  1R5G A;  4IEC A;  2GA2 A;  5CE6 A;  2Q94 A;  4R60 A;  4IKS A;  4U1B A;  4U6J A;  4ZWO A;  4Z7M A;  4U69 A;  3BIP A;  3MX6 A;  2V3Z A;  3ROR A;  1PV9 A;  2EVM A;  4HXX A;  4MAT A;  1C22 A;  2GGC A;  2GU5 A;  4FLL A;  5JFR A;  1YJ3 A;  1QXY A;  2Q92 A;  2GZ5 A;  4IU6 A;  5CDV A;  2B3L A;  2OKN A;  3Q6D A;  3TAV A;  5CIK A;  4S01 A;  4S2T P;  1YVM A;  2BHD A;  4IPA A;  2GG9 A;  5D6F A;  1B6A A;  2BWU A;  4IKR A;  2BB7 A;  2OAZ A;  1WLR A;  1Y1N A;  2BWY A;  3RVA A;  2NQ6 A;  4U6E A;  1XGS A;  3S6B A;  2BN7 A;  3PKC A;  1C21 A;  1KQ9 A;  3MR1 A;  4IF7 A;  4FO7 A;  2EVC A;  3MAT A;  4PV4 A;  5D6E A;  1CHM A;  1KQ0 A;  3IU9 A;  1XNZ A;  1YW8 A;  1WL6 A;  3PKB A;  4ZWU A;  1XGM A;  1XGN A;  2GGB A;  2V3X A;  2BHA A;  4FO8 A;  4S2R P;  4IDY A;  2GG5 A;  3PKD A;  1WL9 A;  4U6Z A;  4A6W A;  5JHU A;  2BH3 A;  2B3H A;  5FCH A;  2GG8 A; 
#chains in the Genus database with same CATH topology
 1N51 A;  2BWW A;  3FMR A;  1C24 A;  4ZNG A;  5CDE A;  2GG0 A;  1WBQ A;  4B28 A;  3BIT A;  3L24 A;  2NQ7 A;  2HOW A;  4RZY A;  1XGO A;  3CB6 A;  2BHC A;  2BWX A;  4U73 A;  4U75 A;  1QXZ A;  1MAT A;  2GG7 A;  4U6W A;  3L7G A;  2V3Y A;  4OOK A;  2MAT A;  3PKA A;  3PKE A;  4EGE A;  1WY2 A;  4FLI A;  4U6C A;  2Q93 A;  4PNC A;  2P9A A;  2GG3 A;  3FM3 A;  2GU4 A;  3IG4 A;  2B3K A;  3TB5 A;  2P99 A;  4S00 A;  1W2M A;  1KP0 A;  4ZWP A;  4FUK A;  2G6P A;  5E5B A;  4KM3 A;  3CB5 A;  2BHB A;  2BWV A;  2GG2 A;  4U70 A;  3CTZ A;  1B59 A;  1C27 A;  4IKU A;  1YW7 A;  1R5H A;  3BIQ A;  4JUQ A;  2BWT A;  4A6V A;  2Q95 A;  4FLK A;  1C23 A;  1YW9 A;  5CLS A;  4RZZ A;  2DFI A;  2V6C A;  1WKM A;  1WN1 A;  3FMQ A;  4IKT A;  2Q8K A;  4FLJ A;  2Q96 A;  5FCF A;  5CNX A;  2GTX A;  2EVO A;  2GU7 A;  4QR8 A;  2ZSG A;  1A16 A;  2EA2 A;  3IU8 A;  1R58 A;  1QZY A;  2IW2 A;  1JAW A;  1W7V A;  3D27 A;  4RGZ 1;  1QXW A;  4U76 A;  2ADU A;  5CDL A;  1O0X A;  2BWS A;  2GU6 A;  2P98 A;  1BOA A;  3IU7 A;  4U71 A;  1M35 A;  1BN5 A;  2EA4 A;  5JI6 A;  4FKC A;  1R5G A;  4IEC A;  2GA2 A;  5CE6 A;  2Q94 A;  4R60 A;  4IKS A;  4U1B A;  4U6J A;  4ZWO A;  4Z7M A;  4U69 A;  3BIP A;  3MX6 A;  2V3Z A;  3ROR A;  1PV9 A;  2EVM A;  4HXX A;  4MAT A;  1C22 A;  2GGC A;  2GU5 A;  4FLL A;  5JFR A;  1YJ3 A;  1QXY A;  2Q92 A;  2GZ5 A;  4IU6 A;  5CDV A;  2B3L A;  2OKN A;  3Q6D A;  3TAV A;  5CIK A;  4S01 A;  4S2T P;  1YVM A;  2BHD A;  4IPA A;  2GG9 A;  5D6F A;  1B6A A;  2BWU A;  4IKR A;  2BB7 A;  2OAZ A;  1WLR A;  1Y1N A;  2BWY A;  3RVA A;  2NQ6 A;  4U6E A;  1XGS A;  3S6B A;  2BN7 A;  3PKC A;  1C21 A;  1KQ9 A;  3MR1 A;  4IF7 A;  4FO7 A;  2EVC A;  3MAT A;  4PV4 A;  5D6E A;  1CHM A;  1KQ0 A;  3IU9 A;  1XNZ A;  1YW8 A;  1WL6 A;  3PKB A;  4ZWU A;  1XGM A;  1XGN A;  2GGB A;  2V3X A;  2BHA A;  4FO8 A;  4S2R P;  4IDY A;  2GG5 A;  3PKD A;  1WL9 A;  4U6Z A;  4A6W A;  5JHU A;  2BH3 A;  2B3H A;  5FCH A;  2GG8 A; 
#chains in the Genus database with same CATH homology
 1N51 A;  2BWW A;  3FMR A;  1C24 A;  4ZNG A;  5CDE A;  2GG0 A;  1WBQ A;  4B28 A;  3BIT A;  3L24 A;  2NQ7 A;  2HOW A;  4RZY A;  1XGO A;  3CB6 A;  2BHC A;  2BWX A;  4U73 A;  4U75 A;  1QXZ A;  1MAT A;  2GG7 A;  4U6W A;  3L7G A;  2V3Y A;  4OOK A;  2MAT A;  3PKA A;  3PKE A;  4EGE A;  1WY2 A;  4FLI A;  4U6C A;  2Q93 A;  4PNC A;  2P9A A;  2GG3 A;  3FM3 A;  2GU4 A;  3IG4 A;  2B3K A;  3TB5 A;  2P99 A;  4S00 A;  1W2M A;  1KP0 A;  4ZWP A;  4FUK A;  2G6P A;  5E5B A;  4KM3 A;  3CB5 A;  2BHB A;  2BWV A;  2GG2 A;  4U70 A;  3CTZ A;  1B59 A;  1C27 A;  4IKU A;  1YW7 A;  1R5H A;  3BIQ A;  4JUQ A;  2BWT A;  4A6V A;  2Q95 A;  4FLK A;  1C23 A;  1YW9 A;  5CLS A;  4RZZ A;  2DFI A;  2V6C A;  1WKM A;  1WN1 A;  3FMQ A;  4IKT A;  2Q8K A;  4FLJ A;  2Q96 A;  5FCF A;  5CNX A;  2GTX A;  2EVO A;  2GU7 A;  4QR8 A;  2ZSG A;  1A16 A;  2EA2 A;  3IU8 A;  1R58 A;  1QZY A;  2IW2 A;  1JAW A;  1W7V A;  3D27 A;  4RGZ 1;  1QXW A;  4U76 A;  2ADU A;  5CDL A;  1O0X A;  2BWS A;  2GU6 A;  2P98 A;  1BOA A;  3IU7 A;  4U71 A;  1M35 A;  1BN5 A;  2EA4 A;  5JI6 A;  4FKC A;  1R5G A;  4IEC A;  2GA2 A;  5CE6 A;  2Q94 A;  4R60 A;  4IKS A;  4U1B A;  4U6J A;  4ZWO A;  4Z7M A;  4U69 A;  3BIP A;  3MX6 A;  2V3Z A;  3ROR A;  1PV9 A;  2EVM A;  4HXX A;  4MAT A;  1C22 A;  2GGC A;  2GU5 A;  4FLL A;  5JFR A;  1YJ3 A;  1QXY A;  2Q92 A;  2GZ5 A;  4IU6 A;  5CDV A;  2B3L A;  2OKN A;  3Q6D A;  3TAV A;  5CIK A;  4S01 A;  4S2T P;  1YVM A;  2BHD A;  4IPA A;  2GG9 A;  5D6F A;  1B6A A;  2BWU A;  4IKR A;  2BB7 A;  2OAZ A;  1WLR A;  1Y1N A;  2BWY A;  3RVA A;  2NQ6 A;  4U6E A;  1XGS A;  3S6B A;  2BN7 A;  3PKC A;  1C21 A;  1KQ9 A;  3MR1 A;  4IF7 A;  4FO7 A;  2EVC A;  3MAT A;  4PV4 A;  5D6E A;  1CHM A;  1KQ0 A;  3IU9 A;  1XNZ A;  1YW8 A;  1WL6 A;  3PKB A;  4ZWU A;  1XGM A;  1XGN A;  2GGB A;  2V3X A;  2BHA A;  4FO8 A;  4S2R P;  4IDY A;  2GG5 A;  3PKD A;  1WL9 A;  4U6Z A;  4A6W A;  5JHU A;  2BH3 A;  2B3H A;  5FCH A;  2GG8 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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