1C24A

E. coli methionine aminopeptidase: methionine phosphinate complex
Total Genus 88
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
88
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 88
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c24A00
5JHUA 1JAWA 3IU7A 1BOAA 2ADUA 5CDVA 5JI6A 2Q95A 4FO8A 3BIQA 4IF7A 1XGOA 1QXYA 2EA4A 4RGZ1 2B3LA 4R60A 2Q93A 1N51A 4S00A 2EVMA 2V3XA 1XGSA 1XNZA 2Q8KA 2GTXA 3L7GA 4IKTA 4MATA 5CLSA 1KQ9A 1CHMA 4U73A 5CNXA 5D6FA 3FMQA 3BITA 2GU4A 1W7VA 2GG3A 2GU5A 4RZZA 2GGCA 4IPAA 4U6ZA 4RZYA 3IU9A 2BWSA 2BWTA 4B28A 3FM3A 4JUQA 2P98A 1A16A 2BWYA 4EGEA 3S6BA 2GG2A 4ZWUA 4PNCA 2EVCA 1O0XA 1B6AA 4A6VA 4QR8A 4PV4A 1YW7A 2BHDA 2Q96A 4U6CA 1YVMA 1YW9A 4IKSA 2BN7A 2ZSGA 2MATA 1MATA 1R5HA 2V6CA 4S2RP 4U71A 1WBQA 2BHBA 4OOKA 3RVAA 4U69A 2BWWA 1XGNA 4IDYA 1WL6A 4HXXA 1KQ0A 4S01A 1WL9A 2OKNA 3PKEA 5JFRA 5E5BA 1QXWA 1Y1NA 4FLLA 2BWUA 5CE6A 1R5GA 1WKMA 3CB5A 4IECA 1XGMA 4U6WA 5D6EA 3TB5A 3CTZA 2GU6A 2GG5A 4IKUA 4ZWOA 1R58A 4U70A 1PV9A 4FUKA 2EA2A 3MR1A 2HOWA 1QXZA 1C24A 2BB7A 3BIPA 1YJ3A 2BH3A 2GGBA 3PKAA 3D27A 5FCHA 2GG0A 4U76A 4Z7MA 2GZ5A 3PKCA 2IW2A 4FLJA 2OAZA 2GG7A 2GG9A 3IU8A 5FCFA 4ZWPA 3Q6DA 1C27A 4FO7A 2EVOA 2P99A 2V3YA 3CB6A 1C22A 4IKRA 5CIKA 4FLIA 2BWXA 4FLKA 4A6WA 2BHCA 4KM3A 4U75A 2GA2A 2DFIA 3RORA 2NQ7A 1B59A 4U6JA 1BN5A 1W2MA 1WY2A 4FKCA 3MX6A 1YW8A 2Q94A 4U6EA 1C21A 2V3ZA 4U1BA 2GG8A 1WLRA 2Q92A 4ZNGA 2B3HA 2P9AA 2B3KA 5CDEA 3FMRA 5CDLA 2NQ6A 1C23A 1M35A 1KP0A 2BHAA 2GU7A 3L24A 2BWVA 3TAVA 3PKDA 3PKBA 1WN1A 4S2TP 3MATA 1QZYA 2G6PA 3IG4A 4IU6A
chains in the Genus database with same CATH superfamily
5JHUA 1JAWA 3IU7A 1BOAA 2ADUA 5CDVA 5JI6A 2Q95A 4FO8A 3BIQA 4IF7A 1XGOA 1QXYA 2EA4A 4RGZ1 2B3LA 4R60A 2Q93A 1N51A 4S00A 2EVMA 2V3XA 1XGSA 1XNZA 2Q8KA 2GTXA 3L7GA 4IKTA 4MATA 5CLSA 1KQ9A 1CHMA 4U73A 5CNXA 5D6FA 3FMQA 3BITA 2GU4A 1W7VA 2GG3A 2GU5A 4RZZA 2GGCA 4IPAA 4U6ZA 4RZYA 3IU9A 2BWSA 2BWTA 4B28A 3FM3A 4JUQA 2P98A 1A16A 2BWYA 4EGEA 3S6BA 2GG2A 4ZWUA 4PNCA 2EVCA 1O0XA 1B6AA 4A6VA 4QR8A 4PV4A 1YW7A 2BHDA 2Q96A 4U6CA 1YVMA 1YW9A 4IKSA 2BN7A 2ZSGA 2MATA 1MATA 1R5HA 2V6CA 4S2RP 4U71A 1WBQA 2BHBA 4OOKA 3RVAA 4U69A 2BWWA 1XGNA 4IDYA 1WL6A 4HXXA 1KQ0A 4S01A 1WL9A 2OKNA 3PKEA 5JFRA 5E5BA 1QXWA 1Y1NA 4FLLA 2BWUA 5CE6A 1R5GA 1WKMA 3CB5A 4IECA 1XGMA 4U6WA 5D6EA 3TB5A 3CTZA 2GU6A 2GG5A 4IKUA 4ZWOA 1R58A 4U70A 1PV9A 4FUKA 2EA2A 3MR1A 2HOWA 1QXZA 1C24A 2BB7A 3BIPA 1YJ3A 2BH3A 2GGBA 3PKAA 3D27A 5FCHA 2GG0A 4U76A 4Z7MA 2GZ5A 3PKCA 2IW2A 4FLJA 2OAZA 2GG7A 2GG9A 3IU8A 5FCFA 4ZWPA 3Q6DA 1C27A 4FO7A 2EVOA 2P99A 2V3YA 3CB6A 1C22A 4IKRA 5CIKA 4FLIA 2BWXA 4FLKA 4A6WA 2BHCA 4KM3A 4U75A 2GA2A 2DFIA 3RORA 2NQ7A 1B59A 4U6JA 1BN5A 1W2MA 1WY2A 4FKCA 3MX6A 1YW8A 2Q94A 4U6EA 1C21A 2V3ZA 4U1BA 2GG8A 1WLRA 2Q92A 4ZNGA 2B3HA 2P9AA 2B3KA 5CDEA 3FMRA 5CDLA 2NQ6A 1C23A 1M35A 1KP0A 2BHAA 2GU7A 3L24A 2BWVA 3TAVA 3PKDA 3PKBA 1WN1A 4S2TP 3MATA 1QZYA 2G6PA 3IG4A 4IU6A
chains in the Genus database with same CATH topology
5JHUA 1JAWA 3IU7A 1BOAA 2ADUA 5CDVA 5JI6A 2Q95A 4FO8A 3BIQA 4IF7A 1XGOA 1QXYA 2EA4A 4RGZ1 2B3LA 4R60A 2Q93A 1N51A 4S00A 2EVMA 2V3XA 1XGSA 1XNZA 2Q8KA 2GTXA 3L7GA 4IKTA 4MATA 5CLSA 1KQ9A 1CHMA 4U73A 5CNXA 5D6FA 3FMQA 3BITA 2GU4A 1W7VA 2GG3A 2GU5A 4RZZA 2GGCA 4IPAA 4U6ZA 4RZYA 3IU9A 2BWSA 2BWTA 4B28A 3FM3A 4JUQA 2P98A 1A16A 2BWYA 4EGEA 3S6BA 2GG2A 4ZWUA 4PNCA 2EVCA 1O0XA 1B6AA 4A6VA 4QR8A 4PV4A 1YW7A 2BHDA 2Q96A 4U6CA 1YVMA 1YW9A 4IKSA 2BN7A 2ZSGA 2MATA 1MATA 1R5HA 2V6CA 4S2RP 4U71A 1WBQA 2BHBA 4OOKA 3RVAA 4U69A 2BWWA 1XGNA 4IDYA 1WL6A 4HXXA 1KQ0A 4S01A 1WL9A 2OKNA 3PKEA 5JFRA 5E5BA 1QXWA 1Y1NA 4FLLA 2BWUA 5CE6A 1R5GA 1WKMA 3CB5A 4IECA 1XGMA 4U6WA 5D6EA 3TB5A 3CTZA 2GU6A 2GG5A 4IKUA 4ZWOA 1R58A 4U70A 1PV9A 4FUKA 2EA2A 3MR1A 2HOWA 1QXZA 1C24A 2BB7A 3BIPA 1YJ3A 2BH3A 2GGBA 3PKAA 3D27A 5FCHA 2GG0A 4U76A 4Z7MA 2GZ5A 3PKCA 2IW2A 4FLJA 2OAZA 2GG7A 2GG9A 3IU8A 5FCFA 4ZWPA 3Q6DA 1C27A 4FO7A 2EVOA 2P99A 2V3YA 3CB6A 1C22A 4IKRA 5CIKA 4FLIA 2BWXA 4FLKA 4A6WA 2BHCA 4KM3A 4U75A 2GA2A 2DFIA 3RORA 2NQ7A 1B59A 4U6JA 1BN5A 1W2MA 1WY2A 4FKCA 3MX6A 1YW8A 2Q94A 4U6EA 1C21A 2V3ZA 4U1BA 2GG8A 1WLRA 2Q92A 4ZNGA 2B3HA 2P9AA 2B3KA 5CDEA 3FMRA 5CDLA 2NQ6A 1C23A 1M35A 1KP0A 2BHAA 2GU7A 3L24A 2BWVA 3TAVA 3PKDA 3PKBA 1WN1A 4S2TP 3MATA 1QZYA 2G6PA 3IG4A 4IU6A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 5JHU A;  1JAW A;  3IU7 A;  1BOA A;  2ADU A;  5CDV A;  5JI6 A;  2Q95 A;  4FO8 A;  3BIQ A;  4IF7 A;  1XGO A;  1QXY A;  2EA4 A;  4RGZ 1;  2B3L A;  4R60 A;  2Q93 A;  1N51 A;  4S00 A;  2EVM A;  2V3X A;  1XGS A;  1XNZ A;  2Q8K A;  2GTX A;  3L7G A;  4IKT A;  4MAT A;  5CLS A;  1KQ9 A;  1CHM A;  4U73 A;  5CNX A;  5D6F A;  3FMQ A;  3BIT A;  2GU4 A;  1W7V A;  2GG3 A;  2GU5 A;  4RZZ A;  2GGC A;  4IPA A;  4U6Z A;  4RZY A;  3IU9 A;  2BWS A;  2BWT A;  4B28 A;  3FM3 A;  4JUQ A;  2P98 A;  1A16 A;  2BWY A;  4EGE A;  3S6B A;  2GG2 A;  4ZWU A;  4PNC A;  2EVC A;  1O0X A;  1B6A A;  4A6V A;  4QR8 A;  4PV4 A;  1YW7 A;  2BHD A;  2Q96 A;  4U6C A;  1YVM A;  1YW9 A;  4IKS A;  2BN7 A;  2ZSG A;  2MAT A;  1MAT A;  1R5H A;  2V6C A;  4S2R P;  4U71 A;  1WBQ A;  2BHB A;  4OOK A;  3RVA A;  4U69 A;  2BWW A;  1XGN A;  4IDY A;  1WL6 A;  4HXX A;  1KQ0 A;  4S01 A;  1WL9 A;  2OKN A;  3PKE A;  5JFR A;  5E5B A;  1QXW A;  1Y1N A;  4FLL A;  2BWU A;  5CE6 A;  1R5G A;  1WKM A;  3CB5 A;  4IEC A;  1XGM A;  4U6W A;  5D6E A;  3TB5 A;  3CTZ A;  2GU6 A;  2GG5 A;  4IKU A;  4ZWO A;  1R58 A;  4U70 A;  1PV9 A;  4FUK A;  2EA2 A;  3MR1 A;  2HOW A;  1QXZ A;  1C24 A;  2BB7 A;  3BIP A;  1YJ3 A;  2BH3 A;  2GGB A;  3PKA A;  3D27 A;  5FCH A;  2GG0 A;  4U76 A;  4Z7M A;  2GZ5 A;  3PKC A;  2IW2 A;  4FLJ A;  2OAZ A;  2GG7 A;  2GG9 A;  3IU8 A;  5FCF A;  4ZWP A;  3Q6D A;  1C27 A;  4FO7 A;  2EVO A;  2P99 A;  2V3Y A;  3CB6 A;  1C22 A;  4IKR A;  5CIK A;  4FLI A;  2BWX A;  4FLK A;  4A6W A;  2BHC A;  4KM3 A;  4U75 A;  2GA2 A;  2DFI A;  3ROR A;  2NQ7 A;  1B59 A;  4U6J A;  1BN5 A;  1W2M A;  1WY2 A;  4FKC A;  3MX6 A;  1YW8 A;  2Q94 A;  4U6E A;  1C21 A;  2V3Z A;  4U1B A;  2GG8 A;  1WLR A;  2Q92 A;  4ZNG A;  2B3H A;  2P9A A;  2B3K A;  5CDE A;  3FMR A;  5CDL A;  2NQ6 A;  1C23 A;  1M35 A;  1KP0 A;  2BHA A;  2GU7 A;  3L24 A;  2BWV A;  3TAV A;  3PKD A;  3PKB A;  1WN1 A;  4S2T P;  3MAT A;  1QZY A;  2G6P A;  3IG4 A;  4IU6 A; 
#chains in the Genus database with same CATH topology
 5JHU A;  1JAW A;  3IU7 A;  1BOA A;  2ADU A;  5CDV A;  5JI6 A;  2Q95 A;  4FO8 A;  3BIQ A;  4IF7 A;  1XGO A;  1QXY A;  2EA4 A;  4RGZ 1;  2B3L A;  4R60 A;  2Q93 A;  1N51 A;  4S00 A;  2EVM A;  2V3X A;  1XGS A;  1XNZ A;  2Q8K A;  2GTX A;  3L7G A;  4IKT A;  4MAT A;  5CLS A;  1KQ9 A;  1CHM A;  4U73 A;  5CNX A;  5D6F A;  3FMQ A;  3BIT A;  2GU4 A;  1W7V A;  2GG3 A;  2GU5 A;  4RZZ A;  2GGC A;  4IPA A;  4U6Z A;  4RZY A;  3IU9 A;  2BWS A;  2BWT A;  4B28 A;  3FM3 A;  4JUQ A;  2P98 A;  1A16 A;  2BWY A;  4EGE A;  3S6B A;  2GG2 A;  4ZWU A;  4PNC A;  2EVC A;  1O0X A;  1B6A A;  4A6V A;  4QR8 A;  4PV4 A;  1YW7 A;  2BHD A;  2Q96 A;  4U6C A;  1YVM A;  1YW9 A;  4IKS A;  2BN7 A;  2ZSG A;  2MAT A;  1MAT A;  1R5H A;  2V6C A;  4S2R P;  4U71 A;  1WBQ A;  2BHB A;  4OOK A;  3RVA A;  4U69 A;  2BWW A;  1XGN A;  4IDY A;  1WL6 A;  4HXX A;  1KQ0 A;  4S01 A;  1WL9 A;  2OKN A;  3PKE A;  5JFR A;  5E5B A;  1QXW A;  1Y1N A;  4FLL A;  2BWU A;  5CE6 A;  1R5G A;  1WKM A;  3CB5 A;  4IEC A;  1XGM A;  4U6W A;  5D6E A;  3TB5 A;  3CTZ A;  2GU6 A;  2GG5 A;  4IKU A;  4ZWO A;  1R58 A;  4U70 A;  1PV9 A;  4FUK A;  2EA2 A;  3MR1 A;  2HOW A;  1QXZ A;  1C24 A;  2BB7 A;  3BIP A;  1YJ3 A;  2BH3 A;  2GGB A;  3PKA A;  3D27 A;  5FCH A;  2GG0 A;  4U76 A;  4Z7M A;  2GZ5 A;  3PKC A;  2IW2 A;  4FLJ A;  2OAZ A;  2GG7 A;  2GG9 A;  3IU8 A;  5FCF A;  4ZWP A;  3Q6D A;  1C27 A;  4FO7 A;  2EVO A;  2P99 A;  2V3Y A;  3CB6 A;  1C22 A;  4IKR A;  5CIK A;  4FLI A;  2BWX A;  4FLK A;  4A6W A;  2BHC A;  4KM3 A;  4U75 A;  2GA2 A;  2DFI A;  3ROR A;  2NQ7 A;  1B59 A;  4U6J A;  1BN5 A;  1W2M A;  1WY2 A;  4FKC A;  3MX6 A;  1YW8 A;  2Q94 A;  4U6E A;  1C21 A;  2V3Z A;  4U1B A;  2GG8 A;  1WLR A;  2Q92 A;  4ZNG A;  2B3H A;  2P9A A;  2B3K A;  5CDE A;  3FMR A;  5CDL A;  2NQ6 A;  1C23 A;  1M35 A;  1KP0 A;  2BHA A;  2GU7 A;  3L24 A;  2BWV A;  3TAV A;  3PKD A;  3PKB A;  1WN1 A;  4S2T P;  3MAT A;  1QZY A;  2G6P A;  3IG4 A;  4IU6 A; 
#chains in the Genus database with same CATH homology
 5JHU A;  1JAW A;  3IU7 A;  1BOA A;  2ADU A;  5CDV A;  5JI6 A;  2Q95 A;  4FO8 A;  3BIQ A;  4IF7 A;  1XGO A;  1QXY A;  2EA4 A;  4RGZ 1;  2B3L A;  4R60 A;  2Q93 A;  1N51 A;  4S00 A;  2EVM A;  2V3X A;  1XGS A;  1XNZ A;  2Q8K A;  2GTX A;  3L7G A;  4IKT A;  4MAT A;  5CLS A;  1KQ9 A;  1CHM A;  4U73 A;  5CNX A;  5D6F A;  3FMQ A;  3BIT A;  2GU4 A;  1W7V A;  2GG3 A;  2GU5 A;  4RZZ A;  2GGC A;  4IPA A;  4U6Z A;  4RZY A;  3IU9 A;  2BWS A;  2BWT A;  4B28 A;  3FM3 A;  4JUQ A;  2P98 A;  1A16 A;  2BWY A;  4EGE A;  3S6B A;  2GG2 A;  4ZWU A;  4PNC A;  2EVC A;  1O0X A;  1B6A A;  4A6V A;  4QR8 A;  4PV4 A;  1YW7 A;  2BHD A;  2Q96 A;  4U6C A;  1YVM A;  1YW9 A;  4IKS A;  2BN7 A;  2ZSG A;  2MAT A;  1MAT A;  1R5H A;  2V6C A;  4S2R P;  4U71 A;  1WBQ A;  2BHB A;  4OOK A;  3RVA A;  4U69 A;  2BWW A;  1XGN A;  4IDY A;  1WL6 A;  4HXX A;  1KQ0 A;  4S01 A;  1WL9 A;  2OKN A;  3PKE A;  5JFR A;  5E5B A;  1QXW A;  1Y1N A;  4FLL A;  2BWU A;  5CE6 A;  1R5G A;  1WKM A;  3CB5 A;  4IEC A;  1XGM A;  4U6W A;  5D6E A;  3TB5 A;  3CTZ A;  2GU6 A;  2GG5 A;  4IKU A;  4ZWO A;  1R58 A;  4U70 A;  1PV9 A;  4FUK A;  2EA2 A;  3MR1 A;  2HOW A;  1QXZ A;  1C24 A;  2BB7 A;  3BIP A;  1YJ3 A;  2BH3 A;  2GGB A;  3PKA A;  3D27 A;  5FCH A;  2GG0 A;  4U76 A;  4Z7M A;  2GZ5 A;  3PKC A;  2IW2 A;  4FLJ A;  2OAZ A;  2GG7 A;  2GG9 A;  3IU8 A;  5FCF A;  4ZWP A;  3Q6D A;  1C27 A;  4FO7 A;  2EVO A;  2P99 A;  2V3Y A;  3CB6 A;  1C22 A;  4IKR A;  5CIK A;  4FLI A;  2BWX A;  4FLK A;  4A6W A;  2BHC A;  4KM3 A;  4U75 A;  2GA2 A;  2DFI A;  3ROR A;  2NQ7 A;  1B59 A;  4U6J A;  1BN5 A;  1W2M A;  1WY2 A;  4FKC A;  3MX6 A;  1YW8 A;  2Q94 A;  4U6E A;  1C21 A;  2V3Z A;  4U1B A;  2GG8 A;  1WLR A;  2Q92 A;  4ZNG A;  2B3H A;  2P9A A;  2B3K A;  5CDE A;  3FMR A;  5CDL A;  2NQ6 A;  1C23 A;  1M35 A;  1KP0 A;  2BHA A;  2GU7 A;  3L24 A;  2BWV A;  3TAV A;  3PKD A;  3PKB A;  1WN1 A;  4S2T P;  3MAT A;  1QZY A;  2G6P A;  3IG4 A;  4IU6 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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