1C27A

E. coli methionine aminopeptidase:norleucine phosphonate complex
Total Genus 85
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
85
sequence length
262
structure length
262
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGQGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHD
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Insights into the mechanism of Escherichia coli methionine aminopeptidase from the structural analysis of reaction products and phosphorus-based transition-state analogues.
pubmed doi rcsb
molecule tags Hydrolase
source organism Escherichia coli
molecule keywords METHIONINE AMINOPEPTIDASE
total genus 85
structure length 262
sequence length 262
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1999-07-22

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1c27A00
2Q94A 3PKEA 1WL9A 1N51A 5JHUA 1XGOA 3RVAA 4IKSA 3FM3A 2P99A 5CDLA 3PKBA 1BN5A 4ZWOA 2GU5A 1M35A 2P98A 2Q95A 5D6EA 1Y1NA 4ZWPA 3S6BA 2GA2A 3TB5A 2B3HA 3CB5A 4Z7MA 5CDVA 1B59A 5CLSA 4U6JA 1QXWA 4B28A 2BWUA 4IKRA 1O0XA 1XGSA 1MATA 4FKCA 1BOAA 5CDEA 1XNZA 1C24A 1WBQA 3PKAA 2GGCA 3L24A 2GG5A 4ZWUA 4S01A 1XGNA 2BWTA 2GG9A 2BHDA 4S2RP 2V3XA 2BB7A 1C23A 2BHBA 4FLJA 2Q93A 3IU8A 2G6PA 2GG3A 2BHAA 4IECA 2GGBA 4U1BA 3IU9A 3FMRA 4RZYA 2GZ5A 1WN1A 1C21A 3IU7A 2NQ7A 4U6ZA 4U70A 5E5BA 4U75A 4S00A 1R5HA 4FLIA 2MATA 3BIQA 1PV9A 4S2TP 4RGZ1 2BWYA 4JUQA 1KP0A 3MX6A 4U69A 4U76A 4PV4A 5FCHA 4U6EA 5JI6A 3BIPA 1QXYA 1W7VA 2Q96A 3Q6DA 4MATA 1XGMA 4FO8A 4FO7A 4EGEA 1YW7A 1C22A 2EVMA 4U71A 4IKUA 2GG0A 2ADUA 2V6CA 2BH3A 1W2MA 1WL6A 1KQ9A 4FLKA 4IKTA 3CB6A 4PNCA 2EVOA 1WY2A 2GTXA 2GU7A 2OAZA 4FUKA 5CNXA 2P9AA 4ZNGA 2B3KA 4QR8A 2GG8A 1R58A 1WKMA 5CIKA 5D6FA 1B6AA 3PKCA 4U6WA 1C27A 2GU4A 3MR1A 4IU6A 4A6WA 1YVMA 2V3YA 4IF7A 4FLLA 2HOWA 2BWVA 2BWXA 1YJ3A 3IG4A 4RZZA 2EA4A 4U6CA 3D27A 5JFRA 2BWWA 2GG2A 3BITA 2ZSGA 2OKNA 1A16A 1QXZA 1JAWA 2B3LA 4OOKA 3PKDA 1YW9A 3CTZA 2BWSA 3FMQA 2BHCA 2EA2A 4KM3A 3TAVA 2NQ6A 5CE6A 4R60A 2GU6A 1QZYA 1WLRA 1YW8A 5FCFA 1KQ0A 3MATA 4U73A 2DFIA 1R5GA 2EVCA 4A6VA 2BN7A 2Q8KA 3RORA 4IPAA 2GG7A 1CHMA 2Q92A 3L7GA 4HXXA 4IDYA 2V3ZA 2IW2A
chains in the Genus database with same CATH superfamily
2Q94A 3PKEA 1WL9A 1N51A 5JHUA 1XGOA 3RVAA 4IKSA 3FM3A 2P99A 5CDLA 3PKBA 1BN5A 4ZWOA 2GU5A 1M35A 2P98A 2Q95A 5D6EA 1Y1NA 4ZWPA 3S6BA 2GA2A 3TB5A 2B3HA 3CB5A 4Z7MA 5CDVA 1B59A 5CLSA 4U6JA 1QXWA 4B28A 2BWUA 4IKRA 1O0XA 1XGSA 1MATA 4FKCA 1BOAA 5CDEA 1XNZA 1C24A 1WBQA 3PKAA 2GGCA 3L24A 2GG5A 4ZWUA 4S01A 1XGNA 2BWTA 2GG9A 2BHDA 4S2RP 2V3XA 2BB7A 1C23A 2BHBA 4FLJA 2Q93A 3IU8A 2G6PA 2GG3A 2BHAA 4IECA 2GGBA 4U1BA 3IU9A 3FMRA 4RZYA 2GZ5A 1WN1A 1C21A 3IU7A 2NQ7A 4U6ZA 4U70A 5E5BA 4U75A 4S00A 1R5HA 4FLIA 2MATA 3BIQA 1PV9A 4S2TP 4RGZ1 2BWYA 4JUQA 1KP0A 3MX6A 4U69A 4U76A 4PV4A 5FCHA 4U6EA 5JI6A 3BIPA 1QXYA 1W7VA 2Q96A 3Q6DA 4MATA 1XGMA 4FO8A 4FO7A 4EGEA 1YW7A 1C22A 2EVMA 4U71A 4IKUA 2GG0A 2ADUA 2V6CA 2BH3A 1W2MA 1WL6A 1KQ9A 4FLKA 4IKTA 3CB6A 4PNCA 2EVOA 1WY2A 2GTXA 2GU7A 2OAZA 4FUKA 5CNXA 2P9AA 4ZNGA 2B3KA 4QR8A 2GG8A 1R58A 1WKMA 5CIKA 5D6FA 1B6AA 3PKCA 4U6WA 1C27A 2GU4A 3MR1A 4IU6A 4A6WA 1YVMA 2V3YA 4IF7A 4FLLA 2HOWA 2BWVA 2BWXA 1YJ3A 3IG4A 4RZZA 2EA4A 4U6CA 3D27A 5JFRA 2BWWA 2GG2A 3BITA 2ZSGA 2OKNA 1A16A 1QXZA 1JAWA 2B3LA 4OOKA 3PKDA 1YW9A 3CTZA 2BWSA 3FMQA 2BHCA 2EA2A 4KM3A 3TAVA 2NQ6A 5CE6A 4R60A 2GU6A 1QZYA 1WLRA 1YW8A 5FCFA 1KQ0A 3MATA 4U73A 2DFIA 1R5GA 2EVCA 4A6VA 2BN7A 2Q8KA 3RORA 4IPAA 2GG7A 1CHMA 2Q92A 3L7GA 4HXXA 4IDYA 2V3ZA 2IW2A
chains in the Genus database with same CATH topology
2Q94A 3PKEA 1WL9A 1N51A 5JHUA 1XGOA 3RVAA 4IKSA 3FM3A 2P99A 5CDLA 3PKBA 1BN5A 4ZWOA 2GU5A 1M35A 2P98A 2Q95A 5D6EA 1Y1NA 4ZWPA 3S6BA 2GA2A 3TB5A 2B3HA 3CB5A 4Z7MA 5CDVA 1B59A 5CLSA 4U6JA 1QXWA 4B28A 2BWUA 4IKRA 1O0XA 1XGSA 1MATA 4FKCA 1BOAA 5CDEA 1XNZA 1C24A 1WBQA 3PKAA 2GGCA 3L24A 2GG5A 4ZWUA 4S01A 1XGNA 2BWTA 2GG9A 2BHDA 4S2RP 2V3XA 2BB7A 1C23A 2BHBA 4FLJA 2Q93A 3IU8A 2G6PA 2GG3A 2BHAA 4IECA 2GGBA 4U1BA 3IU9A 3FMRA 4RZYA 2GZ5A 1WN1A 1C21A 3IU7A 2NQ7A 4U6ZA 4U70A 5E5BA 4U75A 4S00A 1R5HA 4FLIA 2MATA 3BIQA 1PV9A 4S2TP 4RGZ1 2BWYA 4JUQA 1KP0A 3MX6A 4U69A 4U76A 4PV4A 5FCHA 4U6EA 5JI6A 3BIPA 1QXYA 1W7VA 2Q96A 3Q6DA 4MATA 1XGMA 4FO8A 4FO7A 4EGEA 1YW7A 1C22A 2EVMA 4U71A 4IKUA 2GG0A 2ADUA 2V6CA 2BH3A 1W2MA 1WL6A 1KQ9A 4FLKA 4IKTA 3CB6A 4PNCA 2EVOA 1WY2A 2GTXA 2GU7A 2OAZA 4FUKA 5CNXA 2P9AA 4ZNGA 2B3KA 4QR8A 2GG8A 1R58A 1WKMA 5CIKA 5D6FA 1B6AA 3PKCA 4U6WA 1C27A 2GU4A 3MR1A 4IU6A 4A6WA 1YVMA 2V3YA 4IF7A 4FLLA 2HOWA 2BWVA 2BWXA 1YJ3A 3IG4A 4RZZA 2EA4A 4U6CA 3D27A 5JFRA 2BWWA 2GG2A 3BITA 2ZSGA 2OKNA 1A16A 1QXZA 1JAWA 2B3LA 4OOKA 3PKDA 1YW9A 3CTZA 2BWSA 3FMQA 2BHCA 2EA2A 4KM3A 3TAVA 2NQ6A 5CE6A 4R60A 2GU6A 1QZYA 1WLRA 1YW8A 5FCFA 1KQ0A 3MATA 4U73A 2DFIA 1R5GA 2EVCA 4A6VA 2BN7A 2Q8KA 3RORA 4IPAA 2GG7A 1CHMA 2Q92A 3L7GA 4HXXA 4IDYA 2V3ZA 2IW2A
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q94 A;  3PKE A;  1WL9 A;  1N51 A;  5JHU A;  1XGO A;  3RVA A;  4IKS A;  3FM3 A;  2P99 A;  5CDL A;  3PKB A;  1BN5 A;  4ZWO A;  2GU5 A;  1M35 A;  2P98 A;  2Q95 A;  5D6E A;  1Y1N A;  4ZWP A;  3S6B A;  2GA2 A;  3TB5 A;  2B3H A;  3CB5 A;  4Z7M A;  5CDV A;  1B59 A;  5CLS A;  4U6J A;  1QXW A;  4B28 A;  2BWU A;  4IKR A;  1O0X A;  1XGS A;  1MAT A;  4FKC A;  1BOA A;  5CDE A;  1XNZ A;  1C24 A;  1WBQ A;  3PKA A;  2GGC A;  3L24 A;  2GG5 A;  4ZWU A;  4S01 A;  1XGN A;  2BWT A;  2GG9 A;  2BHD A;  4S2R P;  2V3X A;  2BB7 A;  1C23 A;  2BHB A;  4FLJ A;  2Q93 A;  3IU8 A;  2G6P A;  2GG3 A;  2BHA A;  4IEC A;  2GGB A;  4U1B A;  3IU9 A;  3FMR A;  4RZY A;  2GZ5 A;  1WN1 A;  1C21 A;  3IU7 A;  2NQ7 A;  4U6Z A;  4U70 A;  5E5B A;  4U75 A;  4S00 A;  1R5H A;  4FLI A;  2MAT A;  3BIQ A;  1PV9 A;  4S2T P;  4RGZ 1;  2BWY A;  4JUQ A;  1KP0 A;  3MX6 A;  4U69 A;  4U76 A;  4PV4 A;  5FCH A;  4U6E A;  5JI6 A;  3BIP A;  1QXY A;  1W7V A;  2Q96 A;  3Q6D A;  4MAT A;  1XGM A;  4FO8 A;  4FO7 A;  4EGE A;  1YW7 A;  1C22 A;  2EVM A;  4U71 A;  4IKU A;  2GG0 A;  2ADU A;  2V6C A;  2BH3 A;  1W2M A;  1WL6 A;  1KQ9 A;  4FLK A;  4IKT A;  3CB6 A;  4PNC A;  2EVO A;  1WY2 A;  2GTX A;  2GU7 A;  2OAZ A;  4FUK A;  5CNX A;  2P9A A;  4ZNG A;  2B3K A;  4QR8 A;  2GG8 A;  1R58 A;  1WKM A;  5CIK A;  5D6F A;  1B6A A;  3PKC A;  4U6W A;  1C27 A;  2GU4 A;  3MR1 A;  4IU6 A;  4A6W A;  1YVM A;  2V3Y A;  4IF7 A;  4FLL A;  2HOW A;  2BWV A;  2BWX A;  1YJ3 A;  3IG4 A;  4RZZ A;  2EA4 A;  4U6C A;  3D27 A;  5JFR A;  2BWW A;  2GG2 A;  3BIT A;  2ZSG A;  2OKN A;  1A16 A;  1QXZ A;  1JAW A;  2B3L A;  4OOK A;  3PKD A;  1YW9 A;  3CTZ A;  2BWS A;  3FMQ A;  2BHC A;  2EA2 A;  4KM3 A;  3TAV A;  2NQ6 A;  5CE6 A;  4R60 A;  2GU6 A;  1QZY A;  1WLR A;  1YW8 A;  5FCF A;  1KQ0 A;  3MAT A;  4U73 A;  2DFI A;  1R5G A;  2EVC A;  4A6V A;  2BN7 A;  2Q8K A;  3ROR A;  4IPA A;  2GG7 A;  1CHM A;  2Q92 A;  3L7G A;  4HXX A;  4IDY A;  2V3Z A;  2IW2 A; 
#chains in the Genus database with same CATH topology
 2Q94 A;  3PKE A;  1WL9 A;  1N51 A;  5JHU A;  1XGO A;  3RVA A;  4IKS A;  3FM3 A;  2P99 A;  5CDL A;  3PKB A;  1BN5 A;  4ZWO A;  2GU5 A;  1M35 A;  2P98 A;  2Q95 A;  5D6E A;  1Y1N A;  4ZWP A;  3S6B A;  2GA2 A;  3TB5 A;  2B3H A;  3CB5 A;  4Z7M A;  5CDV A;  1B59 A;  5CLS A;  4U6J A;  1QXW A;  4B28 A;  2BWU A;  4IKR A;  1O0X A;  1XGS A;  1MAT A;  4FKC A;  1BOA A;  5CDE A;  1XNZ A;  1C24 A;  1WBQ A;  3PKA A;  2GGC A;  3L24 A;  2GG5 A;  4ZWU A;  4S01 A;  1XGN A;  2BWT A;  2GG9 A;  2BHD A;  4S2R P;  2V3X A;  2BB7 A;  1C23 A;  2BHB A;  4FLJ A;  2Q93 A;  3IU8 A;  2G6P A;  2GG3 A;  2BHA A;  4IEC A;  2GGB A;  4U1B A;  3IU9 A;  3FMR A;  4RZY A;  2GZ5 A;  1WN1 A;  1C21 A;  3IU7 A;  2NQ7 A;  4U6Z A;  4U70 A;  5E5B A;  4U75 A;  4S00 A;  1R5H A;  4FLI A;  2MAT A;  3BIQ A;  1PV9 A;  4S2T P;  4RGZ 1;  2BWY A;  4JUQ A;  1KP0 A;  3MX6 A;  4U69 A;  4U76 A;  4PV4 A;  5FCH A;  4U6E A;  5JI6 A;  3BIP A;  1QXY A;  1W7V A;  2Q96 A;  3Q6D A;  4MAT A;  1XGM A;  4FO8 A;  4FO7 A;  4EGE A;  1YW7 A;  1C22 A;  2EVM A;  4U71 A;  4IKU A;  2GG0 A;  2ADU A;  2V6C A;  2BH3 A;  1W2M A;  1WL6 A;  1KQ9 A;  4FLK A;  4IKT A;  3CB6 A;  4PNC A;  2EVO A;  1WY2 A;  2GTX A;  2GU7 A;  2OAZ A;  4FUK A;  5CNX A;  2P9A A;  4ZNG A;  2B3K A;  4QR8 A;  2GG8 A;  1R58 A;  1WKM A;  5CIK A;  5D6F A;  1B6A A;  3PKC A;  4U6W A;  1C27 A;  2GU4 A;  3MR1 A;  4IU6 A;  4A6W A;  1YVM A;  2V3Y A;  4IF7 A;  4FLL A;  2HOW A;  2BWV A;  2BWX A;  1YJ3 A;  3IG4 A;  4RZZ A;  2EA4 A;  4U6C A;  3D27 A;  5JFR A;  2BWW A;  2GG2 A;  3BIT A;  2ZSG A;  2OKN A;  1A16 A;  1QXZ A;  1JAW A;  2B3L A;  4OOK A;  3PKD A;  1YW9 A;  3CTZ A;  2BWS A;  3FMQ A;  2BHC A;  2EA2 A;  4KM3 A;  3TAV A;  2NQ6 A;  5CE6 A;  4R60 A;  2GU6 A;  1QZY A;  1WLR A;  1YW8 A;  5FCF A;  1KQ0 A;  3MAT A;  4U73 A;  2DFI A;  1R5G A;  2EVC A;  4A6V A;  2BN7 A;  2Q8K A;  3ROR A;  4IPA A;  2GG7 A;  1CHM A;  2Q92 A;  3L7G A;  4HXX A;  4IDY A;  2V3Z A;  2IW2 A; 
#chains in the Genus database with same CATH homology
 2Q94 A;  3PKE A;  1WL9 A;  1N51 A;  5JHU A;  1XGO A;  3RVA A;  4IKS A;  3FM3 A;  2P99 A;  5CDL A;  3PKB A;  1BN5 A;  4ZWO A;  2GU5 A;  1M35 A;  2P98 A;  2Q95 A;  5D6E A;  1Y1N A;  4ZWP A;  3S6B A;  2GA2 A;  3TB5 A;  2B3H A;  3CB5 A;  4Z7M A;  5CDV A;  1B59 A;  5CLS A;  4U6J A;  1QXW A;  4B28 A;  2BWU A;  4IKR A;  1O0X A;  1XGS A;  1MAT A;  4FKC A;  1BOA A;  5CDE A;  1XNZ A;  1C24 A;  1WBQ A;  3PKA A;  2GGC A;  3L24 A;  2GG5 A;  4ZWU A;  4S01 A;  1XGN A;  2BWT A;  2GG9 A;  2BHD A;  4S2R P;  2V3X A;  2BB7 A;  1C23 A;  2BHB A;  4FLJ A;  2Q93 A;  3IU8 A;  2G6P A;  2GG3 A;  2BHA A;  4IEC A;  2GGB A;  4U1B A;  3IU9 A;  3FMR A;  4RZY A;  2GZ5 A;  1WN1 A;  1C21 A;  3IU7 A;  2NQ7 A;  4U6Z A;  4U70 A;  5E5B A;  4U75 A;  4S00 A;  1R5H A;  4FLI A;  2MAT A;  3BIQ A;  1PV9 A;  4S2T P;  4RGZ 1;  2BWY A;  4JUQ A;  1KP0 A;  3MX6 A;  4U69 A;  4U76 A;  4PV4 A;  5FCH A;  4U6E A;  5JI6 A;  3BIP A;  1QXY A;  1W7V A;  2Q96 A;  3Q6D A;  4MAT A;  1XGM A;  4FO8 A;  4FO7 A;  4EGE A;  1YW7 A;  1C22 A;  2EVM A;  4U71 A;  4IKU A;  2GG0 A;  2ADU A;  2V6C A;  2BH3 A;  1W2M A;  1WL6 A;  1KQ9 A;  4FLK A;  4IKT A;  3CB6 A;  4PNC A;  2EVO A;  1WY2 A;  2GTX A;  2GU7 A;  2OAZ A;  4FUK A;  5CNX A;  2P9A A;  4ZNG A;  2B3K A;  4QR8 A;  2GG8 A;  1R58 A;  1WKM A;  5CIK A;  5D6F A;  1B6A A;  3PKC A;  4U6W A;  1C27 A;  2GU4 A;  3MR1 A;  4IU6 A;  4A6W A;  1YVM A;  2V3Y A;  4IF7 A;  4FLL A;  2HOW A;  2BWV A;  2BWX A;  1YJ3 A;  3IG4 A;  4RZZ A;  2EA4 A;  4U6C A;  3D27 A;  5JFR A;  2BWW A;  2GG2 A;  3BIT A;  2ZSG A;  2OKN A;  1A16 A;  1QXZ A;  1JAW A;  2B3L A;  4OOK A;  3PKD A;  1YW9 A;  3CTZ A;  2BWS A;  3FMQ A;  2BHC A;  2EA2 A;  4KM3 A;  3TAV A;  2NQ6 A;  5CE6 A;  4R60 A;  2GU6 A;  1QZY A;  1WLR A;  1YW8 A;  5FCF A;  1KQ0 A;  3MAT A;  4U73 A;  2DFI A;  1R5G A;  2EVC A;  4A6V A;  2BN7 A;  2Q8K A;  3ROR A;  4IPA A;  2GG7 A;  1CHM A;  2Q92 A;  3L7G A;  4HXX A;  4IDY A;  2V3Z A;  2IW2 A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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