1MATA

Structure of the cobalt-dependent methionine aminopeptidase from escherichia coli: a new type of proteolytic enzyme
Total Genus 77
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
77
sequence length
263
structure length
263
Chain Sequence
AISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRICNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIKDGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAEGFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMKDGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.

Chord Diagram
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publication title Structure of the cobalt-dependent methionine aminopeptidase from Escherichia coli: a new type of proteolytic enzyme.
pubmed doi rcsb
molecule tags Hydrolase(alpha-aminoacylpeptide)
source organism Escherichia coli
molecule keywords METHIONYL AMINOPEPTIDASE
total genus 77
structure length 263
sequence length 263
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 1992-12-02

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1matA00
2Q93A 4ZWOA 3FMQA 4FLLA 2Q96A 4QR8A 1WBQA 5JI6A 4S2RP 1W7VA 2OAZA 2NQ7A 2ADUA 3PKEA 2BWWA 4KM3A 4U1BA 2V3ZA 3D27A 3Q6DA 4U70A 2BH3A 2B3HA 2GGCA 2GU6A 4ZWUA 5JHUA 1KP0A 2GG2A 3BIQA 3IG4A 4IKRA 2GG7A 3MATA 1QXZA 2MATA 5FCFA 1MATA 3IU7A 1CHMA 2EVCA 4FKCA 2EVOA 4JUQA 2BN7A 5CE6A 2BWVA 2BHBA 1XNZA 3PKDA 4S2TP 5CIKA 2GG5A 3MR1A 4MATA 4U73A 4IKSA 1R5HA 4U75A 4FUKA 2HOWA 4IDYA 5JFRA 3RVAA 2ZSGA 4U69A 2GU4A 1YW7A 2BWYA 2NQ6A 1C22A 3BIPA 1YJ3A 4U71A 3L24A 4FLIA 2P9AA 2Q92A 4IKTA 3S6BA 1XGOA 1O0XA 2EVMA 1QXYA 2BHAA 4FLKA 3PKCA 1WN1A 5E5BA 2GU5A 4IU6A 4PV4A 2BWSA 3L7GA 2G6PA 4U6WA 2GTXA 1KQ0A 1WY2A 1B6AA 4A6WA 2EA2A 3FM3A 1QZYA 2GU7A 1C27A 4S00A 1N51A 2BWTA 1PV9A 2B3KA 2DFIA 2BHCA 4FLJA 5D6EA 2GG8A 2V6CA 1WL9A 4FO7A 2P98A 2GZ5A 5CDEA 1BOAA 1YVMA 5CNXA 1R58A 2B3LA 2GG3A 5D6FA 2BHDA 5FCHA 4A6VA 4U76A 4IPAA 1A16A 1B59A 1C24A 2GG0A 2EA4A 2V3XA 2GA2A 5CLSA 2Q94A 1WKMA 4B28A 3RORA 1XGNA 3CTZA 2V3YA 4U6ZA 1YW8A 3IU9A 3TB5A 1R5GA 2Q8KA 3IU8A 3PKAA 4HXXA 2BWUA 1BN5A 4IKUA 3TAVA 4RZYA 1WLRA 1C23A 4RGZ1 1Y1NA 1KQ9A 2IW2A 2BB7A 1JAWA 3CB5A 4RZZA 4EGEA 2P99A 3CB6A 1C21A 4U6EA 2GGBA 2OKNA 4PNCA 4U6CA 4OOKA 1YW9A 1QXWA 3FMRA 4R60A 4IECA 4IF7A 1XGSA 2Q95A 4S01A 4U6JA 4ZWPA 3MX6A 4FO8A 1XGMA 5CDLA 2BWXA 1W2MA 3PKBA 4ZNGA 3BITA 2GG9A 5CDVA 1M35A 1WL6A 4Z7MA
chains in the Genus database with same CATH superfamily
2Q93A 4ZWOA 3FMQA 4FLLA 2Q96A 4QR8A 1WBQA 5JI6A 4S2RP 1W7VA 2OAZA 2NQ7A 2ADUA 3PKEA 2BWWA 4KM3A 4U1BA 2V3ZA 3D27A 3Q6DA 4U70A 2BH3A 2B3HA 2GGCA 2GU6A 4ZWUA 5JHUA 1KP0A 2GG2A 3BIQA 3IG4A 4IKRA 2GG7A 3MATA 1QXZA 2MATA 5FCFA 1MATA 3IU7A 1CHMA 2EVCA 4FKCA 2EVOA 4JUQA 2BN7A 5CE6A 2BWVA 2BHBA 1XNZA 3PKDA 4S2TP 5CIKA 2GG5A 3MR1A 4MATA 4U73A 4IKSA 1R5HA 4U75A 4FUKA 2HOWA 4IDYA 5JFRA 3RVAA 2ZSGA 4U69A 2GU4A 1YW7A 2BWYA 2NQ6A 1C22A 3BIPA 1YJ3A 4U71A 3L24A 4FLIA 2P9AA 2Q92A 4IKTA 3S6BA 1XGOA 1O0XA 2EVMA 1QXYA 2BHAA 4FLKA 3PKCA 1WN1A 5E5BA 2GU5A 4IU6A 4PV4A 2BWSA 3L7GA 2G6PA 4U6WA 2GTXA 1KQ0A 1WY2A 1B6AA 4A6WA 2EA2A 3FM3A 1QZYA 2GU7A 1C27A 4S00A 1N51A 2BWTA 1PV9A 2B3KA 2DFIA 2BHCA 4FLJA 5D6EA 2GG8A 2V6CA 1WL9A 4FO7A 2P98A 2GZ5A 5CDEA 1BOAA 1YVMA 5CNXA 1R58A 2B3LA 2GG3A 5D6FA 2BHDA 5FCHA 4A6VA 4U76A 4IPAA 1A16A 1B59A 1C24A 2GG0A 2EA4A 2V3XA 2GA2A 5CLSA 2Q94A 1WKMA 4B28A 3RORA 1XGNA 3CTZA 2V3YA 4U6ZA 1YW8A 3IU9A 3TB5A 1R5GA 2Q8KA 3IU8A 3PKAA 4HXXA 2BWUA 1BN5A 4IKUA 3TAVA 4RZYA 1WLRA 1C23A 4RGZ1 1Y1NA 1KQ9A 2IW2A 2BB7A 1JAWA 3CB5A 4RZZA 4EGEA 2P99A 3CB6A 1C21A 4U6EA 2GGBA 2OKNA 4PNCA 4U6CA 4OOKA 1YW9A 1QXWA 3FMRA 4R60A 4IECA 4IF7A 1XGSA 2Q95A 4S01A 4U6JA 4ZWPA 3MX6A 4FO8A 1XGMA 5CDLA 2BWXA 1W2MA 3PKBA 4ZNGA 3BITA 2GG9A 5CDVA 1M35A 1WL6A 4Z7MA
chains in the Genus database with same CATH topology
2Q93A 4ZWOA 3FMQA 4FLLA 2Q96A 4QR8A 1WBQA 5JI6A 4S2RP 1W7VA 2OAZA 2NQ7A 2ADUA 3PKEA 2BWWA 4KM3A 4U1BA 2V3ZA 3D27A 3Q6DA 4U70A 2BH3A 2B3HA 2GGCA 2GU6A 4ZWUA 5JHUA 1KP0A 2GG2A 3BIQA 3IG4A 4IKRA 2GG7A 3MATA 1QXZA 2MATA 5FCFA 1MATA 3IU7A 1CHMA 2EVCA 4FKCA 2EVOA 4JUQA 2BN7A 5CE6A 2BWVA 2BHBA 1XNZA 3PKDA 4S2TP 5CIKA 2GG5A 3MR1A 4MATA 4U73A 4IKSA 1R5HA 4U75A 4FUKA 2HOWA 4IDYA 5JFRA 3RVAA 2ZSGA 4U69A 2GU4A 1YW7A 2BWYA 2NQ6A 1C22A 3BIPA 1YJ3A 4U71A 3L24A 4FLIA 2P9AA 2Q92A 4IKTA 3S6BA 1XGOA 1O0XA 2EVMA 1QXYA 2BHAA 4FLKA 3PKCA 1WN1A 5E5BA 2GU5A 4IU6A 4PV4A 2BWSA 3L7GA 2G6PA 4U6WA 2GTXA 1KQ0A 1WY2A 1B6AA 4A6WA 2EA2A 3FM3A 1QZYA 2GU7A 1C27A 4S00A 1N51A 2BWTA 1PV9A 2B3KA 2DFIA 2BHCA 4FLJA 5D6EA 2GG8A 2V6CA 1WL9A 4FO7A 2P98A 2GZ5A 5CDEA 1BOAA 1YVMA 5CNXA 1R58A 2B3LA 2GG3A 5D6FA 2BHDA 5FCHA 4A6VA 4U76A 4IPAA 1A16A 1B59A 1C24A 2GG0A 2EA4A 2V3XA 2GA2A 5CLSA 2Q94A 1WKMA 4B28A 3RORA 1XGNA 3CTZA 2V3YA 4U6ZA 1YW8A 3IU9A 3TB5A 1R5GA 2Q8KA 3IU8A 3PKAA 4HXXA 2BWUA 1BN5A 4IKUA 3TAVA 4RZYA 1WLRA 1C23A 4RGZ1 1Y1NA 1KQ9A 2IW2A 2BB7A 1JAWA 3CB5A 4RZZA 4EGEA 2P99A 3CB6A 1C21A 4U6EA 2GGBA 2OKNA 4PNCA 4U6CA 4OOKA 1YW9A 1QXWA 3FMRA 4R60A 4IECA 4IF7A 1XGSA 2Q95A 4S01A 4U6JA 4ZWPA 3MX6A 4FO8A 1XGMA 5CDLA 2BWXA 1W2MA 3PKBA 4ZNGA 3BITA 2GG9A 5CDVA 1M35A 1WL6A 4Z7MA
chains in the Genus database with same CATH homology


 
#chains in the Genus database with same CATH superfamily
 2Q93 A;  4ZWO A;  3FMQ A;  4FLL A;  2Q96 A;  4QR8 A;  1WBQ A;  5JI6 A;  4S2R P;  1W7V A;  2OAZ A;  2NQ7 A;  2ADU A;  3PKE A;  2BWW A;  4KM3 A;  4U1B A;  2V3Z A;  3D27 A;  3Q6D A;  4U70 A;  2BH3 A;  2B3H A;  2GGC A;  2GU6 A;  4ZWU A;  5JHU A;  1KP0 A;  2GG2 A;  3BIQ A;  3IG4 A;  4IKR A;  2GG7 A;  3MAT A;  1QXZ A;  2MAT A;  5FCF A;  1MAT A;  3IU7 A;  1CHM A;  2EVC A;  4FKC A;  2EVO A;  4JUQ A;  2BN7 A;  5CE6 A;  2BWV A;  2BHB A;  1XNZ A;  3PKD A;  4S2T P;  5CIK A;  2GG5 A;  3MR1 A;  4MAT A;  4U73 A;  4IKS A;  1R5H A;  4U75 A;  4FUK A;  2HOW A;  4IDY A;  5JFR A;  3RVA A;  2ZSG A;  4U69 A;  2GU4 A;  1YW7 A;  2BWY A;  2NQ6 A;  1C22 A;  3BIP A;  1YJ3 A;  4U71 A;  3L24 A;  4FLI A;  2P9A A;  2Q92 A;  4IKT A;  3S6B A;  1XGO A;  1O0X A;  2EVM A;  1QXY A;  2BHA A;  4FLK A;  3PKC A;  1WN1 A;  5E5B A;  2GU5 A;  4IU6 A;  4PV4 A;  2BWS A;  3L7G A;  2G6P A;  4U6W A;  2GTX A;  1KQ0 A;  1WY2 A;  1B6A A;  4A6W A;  2EA2 A;  3FM3 A;  1QZY A;  2GU7 A;  1C27 A;  4S00 A;  1N51 A;  2BWT A;  1PV9 A;  2B3K A;  2DFI A;  2BHC A;  4FLJ A;  5D6E A;  2GG8 A;  2V6C A;  1WL9 A;  4FO7 A;  2P98 A;  2GZ5 A;  5CDE A;  1BOA A;  1YVM A;  5CNX A;  1R58 A;  2B3L A;  2GG3 A;  5D6F A;  2BHD A;  5FCH A;  4A6V A;  4U76 A;  4IPA A;  1A16 A;  1B59 A;  1C24 A;  2GG0 A;  2EA4 A;  2V3X A;  2GA2 A;  5CLS A;  2Q94 A;  1WKM A;  4B28 A;  3ROR A;  1XGN A;  3CTZ A;  2V3Y A;  4U6Z A;  1YW8 A;  3IU9 A;  3TB5 A;  1R5G A;  2Q8K A;  3IU8 A;  3PKA A;  4HXX A;  2BWU A;  1BN5 A;  4IKU A;  3TAV A;  4RZY A;  1WLR A;  1C23 A;  4RGZ 1;  1Y1N A;  1KQ9 A;  2IW2 A;  2BB7 A;  1JAW A;  3CB5 A;  4RZZ A;  4EGE A;  2P99 A;  3CB6 A;  1C21 A;  4U6E A;  2GGB A;  2OKN A;  4PNC A;  4U6C A;  4OOK A;  1YW9 A;  1QXW A;  3FMR A;  4R60 A;  4IEC A;  4IF7 A;  1XGS A;  2Q95 A;  4S01 A;  4U6J A;  4ZWP A;  3MX6 A;  4FO8 A;  1XGM A;  5CDL A;  2BWX A;  1W2M A;  3PKB A;  4ZNG A;  3BIT A;  2GG9 A;  5CDV A;  1M35 A;  1WL6 A;  4Z7M A; 
#chains in the Genus database with same CATH topology
 2Q93 A;  4ZWO A;  3FMQ A;  4FLL A;  2Q96 A;  4QR8 A;  1WBQ A;  5JI6 A;  4S2R P;  1W7V A;  2OAZ A;  2NQ7 A;  2ADU A;  3PKE A;  2BWW A;  4KM3 A;  4U1B A;  2V3Z A;  3D27 A;  3Q6D A;  4U70 A;  2BH3 A;  2B3H A;  2GGC A;  2GU6 A;  4ZWU A;  5JHU A;  1KP0 A;  2GG2 A;  3BIQ A;  3IG4 A;  4IKR A;  2GG7 A;  3MAT A;  1QXZ A;  2MAT A;  5FCF A;  1MAT A;  3IU7 A;  1CHM A;  2EVC A;  4FKC A;  2EVO A;  4JUQ A;  2BN7 A;  5CE6 A;  2BWV A;  2BHB A;  1XNZ A;  3PKD A;  4S2T P;  5CIK A;  2GG5 A;  3MR1 A;  4MAT A;  4U73 A;  4IKS A;  1R5H A;  4U75 A;  4FUK A;  2HOW A;  4IDY A;  5JFR A;  3RVA A;  2ZSG A;  4U69 A;  2GU4 A;  1YW7 A;  2BWY A;  2NQ6 A;  1C22 A;  3BIP A;  1YJ3 A;  4U71 A;  3L24 A;  4FLI A;  2P9A A;  2Q92 A;  4IKT A;  3S6B A;  1XGO A;  1O0X A;  2EVM A;  1QXY A;  2BHA A;  4FLK A;  3PKC A;  1WN1 A;  5E5B A;  2GU5 A;  4IU6 A;  4PV4 A;  2BWS A;  3L7G A;  2G6P A;  4U6W A;  2GTX A;  1KQ0 A;  1WY2 A;  1B6A A;  4A6W A;  2EA2 A;  3FM3 A;  1QZY A;  2GU7 A;  1C27 A;  4S00 A;  1N51 A;  2BWT A;  1PV9 A;  2B3K A;  2DFI A;  2BHC A;  4FLJ A;  5D6E A;  2GG8 A;  2V6C A;  1WL9 A;  4FO7 A;  2P98 A;  2GZ5 A;  5CDE A;  1BOA A;  1YVM A;  5CNX A;  1R58 A;  2B3L A;  2GG3 A;  5D6F A;  2BHD A;  5FCH A;  4A6V A;  4U76 A;  4IPA A;  1A16 A;  1B59 A;  1C24 A;  2GG0 A;  2EA4 A;  2V3X A;  2GA2 A;  5CLS A;  2Q94 A;  1WKM A;  4B28 A;  3ROR A;  1XGN A;  3CTZ A;  2V3Y A;  4U6Z A;  1YW8 A;  3IU9 A;  3TB5 A;  1R5G A;  2Q8K A;  3IU8 A;  3PKA A;  4HXX A;  2BWU A;  1BN5 A;  4IKU A;  3TAV A;  4RZY A;  1WLR A;  1C23 A;  4RGZ 1;  1Y1N A;  1KQ9 A;  2IW2 A;  2BB7 A;  1JAW A;  3CB5 A;  4RZZ A;  4EGE A;  2P99 A;  3CB6 A;  1C21 A;  4U6E A;  2GGB A;  2OKN A;  4PNC A;  4U6C A;  4OOK A;  1YW9 A;  1QXW A;  3FMR A;  4R60 A;  4IEC A;  4IF7 A;  1XGS A;  2Q95 A;  4S01 A;  4U6J A;  4ZWP A;  3MX6 A;  4FO8 A;  1XGM A;  5CDL A;  2BWX A;  1W2M A;  3PKB A;  4ZNG A;  3BIT A;  2GG9 A;  5CDV A;  1M35 A;  1WL6 A;  4Z7M A; 
#chains in the Genus database with same CATH homology
 2Q93 A;  4ZWO A;  3FMQ A;  4FLL A;  2Q96 A;  4QR8 A;  1WBQ A;  5JI6 A;  4S2R P;  1W7V A;  2OAZ A;  2NQ7 A;  2ADU A;  3PKE A;  2BWW A;  4KM3 A;  4U1B A;  2V3Z A;  3D27 A;  3Q6D A;  4U70 A;  2BH3 A;  2B3H A;  2GGC A;  2GU6 A;  4ZWU A;  5JHU A;  1KP0 A;  2GG2 A;  3BIQ A;  3IG4 A;  4IKR A;  2GG7 A;  3MAT A;  1QXZ A;  2MAT A;  5FCF A;  1MAT A;  3IU7 A;  1CHM A;  2EVC A;  4FKC A;  2EVO A;  4JUQ A;  2BN7 A;  5CE6 A;  2BWV A;  2BHB A;  1XNZ A;  3PKD A;  4S2T P;  5CIK A;  2GG5 A;  3MR1 A;  4MAT A;  4U73 A;  4IKS A;  1R5H A;  4U75 A;  4FUK A;  2HOW A;  4IDY A;  5JFR A;  3RVA A;  2ZSG A;  4U69 A;  2GU4 A;  1YW7 A;  2BWY A;  2NQ6 A;  1C22 A;  3BIP A;  1YJ3 A;  4U71 A;  3L24 A;  4FLI A;  2P9A A;  2Q92 A;  4IKT A;  3S6B A;  1XGO A;  1O0X A;  2EVM A;  1QXY A;  2BHA A;  4FLK A;  3PKC A;  1WN1 A;  5E5B A;  2GU5 A;  4IU6 A;  4PV4 A;  2BWS A;  3L7G A;  2G6P A;  4U6W A;  2GTX A;  1KQ0 A;  1WY2 A;  1B6A A;  4A6W A;  2EA2 A;  3FM3 A;  1QZY A;  2GU7 A;  1C27 A;  4S00 A;  1N51 A;  2BWT A;  1PV9 A;  2B3K A;  2DFI A;  2BHC A;  4FLJ A;  5D6E A;  2GG8 A;  2V6C A;  1WL9 A;  4FO7 A;  2P98 A;  2GZ5 A;  5CDE A;  1BOA A;  1YVM A;  5CNX A;  1R58 A;  2B3L A;  2GG3 A;  5D6F A;  2BHD A;  5FCH A;  4A6V A;  4U76 A;  4IPA A;  1A16 A;  1B59 A;  1C24 A;  2GG0 A;  2EA4 A;  2V3X A;  2GA2 A;  5CLS A;  2Q94 A;  1WKM A;  4B28 A;  3ROR A;  1XGN A;  3CTZ A;  2V3Y A;  4U6Z A;  1YW8 A;  3IU9 A;  3TB5 A;  1R5G A;  2Q8K A;  3IU8 A;  3PKA A;  4HXX A;  2BWU A;  1BN5 A;  4IKU A;  3TAV A;  4RZY A;  1WLR A;  1C23 A;  4RGZ 1;  1Y1N A;  1KQ9 A;  2IW2 A;  2BB7 A;  1JAW A;  3CB5 A;  4RZZ A;  4EGE A;  2P99 A;  3CB6 A;  1C21 A;  4U6E A;  2GGB A;  2OKN A;  4PNC A;  4U6C A;  4OOK A;  1YW9 A;  1QXW A;  3FMR A;  4R60 A;  4IEC A;  4IF7 A;  1XGS A;  2Q95 A;  4S01 A;  4U6J A;  4ZWP A;  3MX6 A;  4FO8 A;  1XGM A;  5CDL A;  2BWX A;  1W2M A;  3PKB A;  4ZNG A;  3BIT A;  2GG9 A;  5CDV A;  1M35 A;  1WL6 A;  4Z7M A; 
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

 
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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