1O0XA

Crystal structure of methionine aminopeptidase (tm1478) from thermotoga maritima at 1.90 a resolution
Total Genus 84
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The genus trace: a function that shows values of genus (vertical axis) for subchains spanned between the first residue, and all other residues (shown on horizontal axis). The number of the latter residue and the genus of a given subchain are shown interactively.

Total Genus
84
sequence length
249
structure length
249
Chain Sequence
MIRIKTPSEIEKMKKAGKAVAVALREVRKVIVPGKTAWDVETLVLEIFKKLRVKPAFKGYGGYKYATCVSVNEEVVHGLPLKEKVFKEGDIVSVDVGAVYQGLYGDAAVTYIVGETDERGKELVRVTREVLEKAIKMIKPGIRLGDVSHCIQETVESVGFNVIRDYVGHGVGRELHEDPQIPNYGTPGTGVVLRKGMTLAIEPMVSEGDWRVVVKEDGWTAVTVDGSRCAHFEHTILITENGAEILTKE
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The genus matrix. At position (x,y) a genus value for a subchain spanned between x’th and y’th residue is shown. Values of the genus are represented by color, according to the scale given on the right.

Structure visualization

After clicking on a point (x,y) in the genus matrix above, a subchain from x to y is shown in color.


  Genus data interpretation
Chord Diagram
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publication title Crystal structure of a methionine aminopeptidase (TM1478) from Thermotoga maritima at 1.9 A resolution.
pubmed doi rcsb
molecule tags Hydrolase
source organism Thermotoga maritima
molecule keywords Methionine aminopeptidase
total genus 84
structure length 249
sequence length 249
ec nomenclature ec 3.4.11.18: Methionyl aminopeptidase.
pdb deposition date 2002-09-13

pfam database annotations

chain Pfam Accession Code Pfam Family Identifier Pfam Description
A PF00557 Peptidase_M24 Metallopeptidase family M24
Image from the rcsb pdb (www.rcsb.org)
cath code
ClassArchitectureTopologyHomologyDomain
3.90.230.10 Alpha Beta Alpha-Beta Complex Creatine Amidinohydrolase Creatinase/methionine aminopeptidase superfamily 1o0xA00
3PKDA 1W2MA 5CDVA 2B3KA 4RZZA 1QXYA 1R5GA 4U6JA 2V3XA 5CIKA 4HXXA 2GA2A 1B59A 2GGCA 2EVOA 4S2TP 2Q93A 4U6WA 2GG7A 1XGSA 3TAVA 2BWUA 2GU5A 3Q6DA 5JFRA 1QXWA 4IKUA 1QXZA 2DFIA 1XGNA 5CNXA 2P99A 1BOAA 1QZYA 4B28A 1N51A 2BWWA 5D6EA 2V6CA 1C21A 5CDEA 4U76A 1CHMA 1C24A 3CB6A 4OOKA 1WKMA 1M35A 1XNZA 2B3LA 2Q92A 3PKEA 4QR8A 2OKNA 3BITA 2BN7A 3TB5A 4IKRA 1KQ0A 3RVAA 3BIPA 2BWVA 4IECA 1Y1NA 4IKSA 1WBQA 4IPAA 4RGZ1 5D6FA 1WN1A 2GG2A 3S6BA 2GG0A 4FLIA 2BWXA 3D27A 2P98A 2BWTA 2G6PA 2ADUA 2Q95A 1WLRA 4FLKA 4U70A 3PKBA 2EA4A 2BB7A 5CDLA 3PKCA 4S00A 2EVMA 4IDYA 1W7VA 4FLLA 4MATA 2GGBA 2Q94A 4U6EA 3IU8A 2BH3A 3MATA 4A6VA 2GU6A 3IG4A 2V3ZA 1C27A 5JI6A 1WY2A 1C23A 2GG8A 1YW9A 4PNCA 4IF7A 1MATA 2HOWA 2BWYA 1R58A 1KP0A 4ZNGA 4Z7MA 4S2RP 1KQ9A 1B6AA 4FLJA 3L24A 4FKCA 4S01A 2GG5A 2GZ5A 2ZSGA 3PKAA 4KM3A 1YVMA 3CTZA 4EGEA 4FO8A 5CLSA 5E5BA 1PV9A 4IKTA 3IU7A 4U1BA 4R60A 4ZWPA 4FO7A 2BHBA 2BWSA 2GG3A 4PV4A 4FUKA 2P9AA 3RORA 1YW7A 2NQ7A 1A16A 2BHCA 3FMRA 4U75A 1BN5A 3L7GA 4U6ZA 2IW2A 2B3HA 4IU6A 5JHUA 3IU9A 1JAWA 1R5HA 3CB5A 5FCHA 4U6CA 2V3YA 3FMQA 3MX6A 4U69A 4ZWUA 2BHAA 2EVCA 5CE6A 2EA2A 1YW8A 1YJ3A 2GTXA 3FM3A 1XGOA 2GU4A 3MR1A 4U73A 2MATA 2Q96A 2Q8KA 1C22A 1XGMA 5FCFA 1O0XA 2BHDA 4JUQA 2GG9A 4ZWOA 2NQ6A 2OAZA 1WL9A 4RZYA 3BIQA 4U71A 2GU7A 1WL6A 4A6WA
chains in the Genus database with same CATH superfamily
3PKDA 1W2MA 5CDVA 2B3KA 4RZZA 1QXYA 1R5GA 4U6JA 2V3XA 5CIKA 4HXXA 2GA2A 1B59A 2GGCA 2EVOA 4S2TP 2Q93A 4U6WA 2GG7A 1XGSA 3TAVA 2BWUA 2GU5A 3Q6DA 5JFRA 1QXWA 4IKUA 1QXZA 2DFIA 1XGNA 5CNXA 2P99A 1BOAA 1QZYA 4B28A 1N51A 2BWWA 5D6EA 2V6CA 1C21A 5CDEA 4U76A 1CHMA 1C24A 3CB6A 4OOKA 1WKMA 1M35A 1XNZA 2B3LA 2Q92A 3PKEA 4QR8A 2OKNA 3BITA 2BN7A 3TB5A 4IKRA 1KQ0A 3RVAA 3BIPA 2BWVA 4IECA 1Y1NA 4IKSA 1WBQA 4IPAA 4RGZ1 5D6FA 1WN1A 2GG2A 3S6BA 2GG0A 4FLIA 2BWXA 3D27A 2P98A 2BWTA 2G6PA 2ADUA 2Q95A 1WLRA 4FLKA 4U70A 3PKBA 2EA4A 2BB7A 5CDLA 3PKCA 4S00A 2EVMA 4IDYA 1W7VA 4FLLA 4MATA 2GGBA 2Q94A 4U6EA 3IU8A 2BH3A 3MATA 4A6VA 2GU6A 3IG4A 2V3ZA 1C27A 5JI6A 1WY2A 1C23A 2GG8A 1YW9A 4PNCA 4IF7A 1MATA 2HOWA 2BWYA 1R58A 1KP0A 4ZNGA 4Z7MA 4S2RP 1KQ9A 1B6AA 4FLJA 3L24A 4FKCA 4S01A 2GG5A 2GZ5A 2ZSGA 3PKAA 4KM3A 1YVMA 3CTZA 4EGEA 4FO8A 5CLSA 5E5BA 1PV9A 4IKTA 3IU7A 4U1BA 4R60A 4ZWPA 4FO7A 2BHBA 2BWSA 2GG3A 4PV4A 4FUKA 2P9AA 3RORA 1YW7A 2NQ7A 1A16A 2BHCA 3FMRA 4U75A 1BN5A 3L7GA 4U6ZA 2IW2A 2B3HA 4IU6A 5JHUA 3IU9A 1JAWA 1R5HA 3CB5A 5FCHA 4U6CA 2V3YA 3FMQA 3MX6A 4U69A 4ZWUA 2BHAA 2EVCA 5CE6A 2EA2A 1YW8A 1YJ3A 2GTXA 3FM3A 1XGOA 2GU4A 3MR1A 4U73A 2MATA 2Q96A 2Q8KA 1C22A 1XGMA 5FCFA 1O0XA 2BHDA 4JUQA 2GG9A 4ZWOA 2NQ6A 2OAZA 1WL9A 4RZYA 3BIQA 4U71A 2GU7A 1WL6A 4A6WA
chains in the Genus database with same CATH topology
3PKDA 1W2MA 5CDVA 2B3KA 4RZZA 1QXYA 1R5GA 4U6JA 2V3XA 5CIKA 4HXXA 2GA2A 1B59A 2GGCA 2EVOA 4S2TP 2Q93A 4U6WA 2GG7A 1XGSA 3TAVA 2BWUA 2GU5A 3Q6DA 5JFRA 1QXWA 4IKUA 1QXZA 2DFIA 1XGNA 5CNXA 2P99A 1BOAA 1QZYA 4B28A 1N51A 2BWWA 5D6EA 2V6CA 1C21A 5CDEA 4U76A 1CHMA 1C24A 3CB6A 4OOKA 1WKMA 1M35A 1XNZA 2B3LA 2Q92A 3PKEA 4QR8A 2OKNA 3BITA 2BN7A 3TB5A 4IKRA 1KQ0A 3RVAA 3BIPA 2BWVA 4IECA 1Y1NA 4IKSA 1WBQA 4IPAA 4RGZ1 5D6FA 1WN1A 2GG2A 3S6BA 2GG0A 4FLIA 2BWXA 3D27A 2P98A 2BWTA 2G6PA 2ADUA 2Q95A 1WLRA 4FLKA 4U70A 3PKBA 2EA4A 2BB7A 5CDLA 3PKCA 4S00A 2EVMA 4IDYA 1W7VA 4FLLA 4MATA 2GGBA 2Q94A 4U6EA 3IU8A 2BH3A 3MATA 4A6VA 2GU6A 3IG4A 2V3ZA 1C27A 5JI6A 1WY2A 1C23A 2GG8A 1YW9A 4PNCA 4IF7A 1MATA 2HOWA 2BWYA 1R58A 1KP0A 4ZNGA 4Z7MA 4S2RP 1KQ9A 1B6AA 4FLJA 3L24A 4FKCA 4S01A 2GG5A 2GZ5A 2ZSGA 3PKAA 4KM3A 1YVMA 3CTZA 4EGEA 4FO8A 5CLSA 5E5BA 1PV9A 4IKTA 3IU7A 4U1BA 4R60A 4ZWPA 4FO7A 2BHBA 2BWSA 2GG3A 4PV4A 4FUKA 2P9AA 3RORA 1YW7A 2NQ7A 1A16A 2BHCA 3FMRA 4U75A 1BN5A 3L7GA 4U6ZA 2IW2A 2B3HA 4IU6A 5JHUA 3IU9A 1JAWA 1R5HA 3CB5A 5FCHA 4U6CA 2V3YA 3FMQA 3MX6A 4U69A 4ZWUA 2BHAA 2EVCA 5CE6A 2EA2A 1YW8A 1YJ3A 2GTXA 3FM3A 1XGOA 2GU4A 3MR1A 4U73A 2MATA 2Q96A 2Q8KA 1C22A 1XGMA 5FCFA 1O0XA 2BHDA 4JUQA 2GG9A 4ZWOA 2NQ6A 2OAZA 1WL9A 4RZYA 3BIQA 4U71A 2GU7A 1WL6A 4A6WA
chains in the Genus database with same CATH homology

  
#chains in the Genus database with same CATH superfamily
 3PKD A;  1W2M A;  5CDV A;  2B3K A;  4RZZ A;  1QXY A;  1R5G A;  4U6J A;  2V3X A;  5CIK A;  4HXX A;  2GA2 A;  1B59 A;  2GGC A;  2EVO A;  4S2T P;  2Q93 A;  4U6W A;  2GG7 A;  1XGS A;  3TAV A;  2BWU A;  2GU5 A;  3Q6D A;  5JFR A;  1QXW A;  4IKU A;  1QXZ A;  2DFI A;  1XGN A;  5CNX A;  2P99 A;  1BOA A;  1QZY A;  4B28 A;  1N51 A;  2BWW A;  5D6E A;  2V6C A;  1C21 A;  5CDE A;  4U76 A;  1CHM A;  1C24 A;  3CB6 A;  4OOK A;  1WKM A;  1M35 A;  1XNZ A;  2B3L A;  2Q92 A;  3PKE A;  4QR8 A;  2OKN A;  3BIT A;  2BN7 A;  3TB5 A;  4IKR A;  1KQ0 A;  3RVA A;  3BIP A;  2BWV A;  4IEC A;  1Y1N A;  4IKS A;  1WBQ A;  4IPA A;  4RGZ 1;  5D6F A;  1WN1 A;  2GG2 A;  3S6B A;  2GG0 A;  4FLI A;  2BWX A;  3D27 A;  2P98 A;  2BWT A;  2G6P A;  2ADU A;  2Q95 A;  1WLR A;  4FLK A;  4U70 A;  3PKB A;  2EA4 A;  2BB7 A;  5CDL A;  3PKC A;  4S00 A;  2EVM A;  4IDY A;  1W7V A;  4FLL A;  4MAT A;  2GGB A;  2Q94 A;  4U6E A;  3IU8 A;  2BH3 A;  3MAT A;  4A6V A;  2GU6 A;  3IG4 A;  2V3Z A;  1C27 A;  5JI6 A;  1WY2 A;  1C23 A;  2GG8 A;  1YW9 A;  4PNC A;  4IF7 A;  1MAT A;  2HOW A;  2BWY A;  1R58 A;  1KP0 A;  4ZNG A;  4Z7M A;  4S2R P;  1KQ9 A;  1B6A A;  4FLJ A;  3L24 A;  4FKC A;  4S01 A;  2GG5 A;  2GZ5 A;  2ZSG A;  3PKA A;  4KM3 A;  1YVM A;  3CTZ A;  4EGE A;  4FO8 A;  5CLS A;  5E5B A;  1PV9 A;  4IKT A;  3IU7 A;  4U1B A;  4R60 A;  4ZWP A;  4FO7 A;  2BHB A;  2BWS A;  2GG3 A;  4PV4 A;  4FUK A;  2P9A A;  3ROR A;  1YW7 A;  2NQ7 A;  1A16 A;  2BHC A;  3FMR A;  4U75 A;  1BN5 A;  3L7G A;  4U6Z A;  2IW2 A;  2B3H A;  4IU6 A;  5JHU A;  3IU9 A;  1JAW A;  1R5H A;  3CB5 A;  5FCH A;  4U6C A;  2V3Y A;  3FMQ A;  3MX6 A;  4U69 A;  4ZWU A;  2BHA A;  2EVC A;  5CE6 A;  2EA2 A;  1YW8 A;  1YJ3 A;  2GTX A;  3FM3 A;  1XGO A;  2GU4 A;  3MR1 A;  4U73 A;  2MAT A;  2Q96 A;  2Q8K A;  1C22 A;  1XGM A;  5FCF A;  1O0X A;  2BHD A;  4JUQ A;  2GG9 A;  4ZWO A;  2NQ6 A;  2OAZ A;  1WL9 A;  4RZY A;  3BIQ A;  4U71 A;  2GU7 A;  1WL6 A;  4A6W A; 
#chains in the Genus database with same CATH topology
 3PKD A;  1W2M A;  5CDV A;  2B3K A;  4RZZ A;  1QXY A;  1R5G A;  4U6J A;  2V3X A;  5CIK A;  4HXX A;  2GA2 A;  1B59 A;  2GGC A;  2EVO A;  4S2T P;  2Q93 A;  4U6W A;  2GG7 A;  1XGS A;  3TAV A;  2BWU A;  2GU5 A;  3Q6D A;  5JFR A;  1QXW A;  4IKU A;  1QXZ A;  2DFI A;  1XGN A;  5CNX A;  2P99 A;  1BOA A;  1QZY A;  4B28 A;  1N51 A;  2BWW A;  5D6E A;  2V6C A;  1C21 A;  5CDE A;  4U76 A;  1CHM A;  1C24 A;  3CB6 A;  4OOK A;  1WKM A;  1M35 A;  1XNZ A;  2B3L A;  2Q92 A;  3PKE A;  4QR8 A;  2OKN A;  3BIT A;  2BN7 A;  3TB5 A;  4IKR A;  1KQ0 A;  3RVA A;  3BIP A;  2BWV A;  4IEC A;  1Y1N A;  4IKS A;  1WBQ A;  4IPA A;  4RGZ 1;  5D6F A;  1WN1 A;  2GG2 A;  3S6B A;  2GG0 A;  4FLI A;  2BWX A;  3D27 A;  2P98 A;  2BWT A;  2G6P A;  2ADU A;  2Q95 A;  1WLR A;  4FLK A;  4U70 A;  3PKB A;  2EA4 A;  2BB7 A;  5CDL A;  3PKC A;  4S00 A;  2EVM A;  4IDY A;  1W7V A;  4FLL A;  4MAT A;  2GGB A;  2Q94 A;  4U6E A;  3IU8 A;  2BH3 A;  3MAT A;  4A6V A;  2GU6 A;  3IG4 A;  2V3Z A;  1C27 A;  5JI6 A;  1WY2 A;  1C23 A;  2GG8 A;  1YW9 A;  4PNC A;  4IF7 A;  1MAT A;  2HOW A;  2BWY A;  1R58 A;  1KP0 A;  4ZNG A;  4Z7M A;  4S2R P;  1KQ9 A;  1B6A A;  4FLJ A;  3L24 A;  4FKC A;  4S01 A;  2GG5 A;  2GZ5 A;  2ZSG A;  3PKA A;  4KM3 A;  1YVM A;  3CTZ A;  4EGE A;  4FO8 A;  5CLS A;  5E5B A;  1PV9 A;  4IKT A;  3IU7 A;  4U1B A;  4R60 A;  4ZWP A;  4FO7 A;  2BHB A;  2BWS A;  2GG3 A;  4PV4 A;  4FUK A;  2P9A A;  3ROR A;  1YW7 A;  2NQ7 A;  1A16 A;  2BHC A;  3FMR A;  4U75 A;  1BN5 A;  3L7G A;  4U6Z A;  2IW2 A;  2B3H A;  4IU6 A;  5JHU A;  3IU9 A;  1JAW A;  1R5H A;  3CB5 A;  5FCH A;  4U6C A;  2V3Y A;  3FMQ A;  3MX6 A;  4U69 A;  4ZWU A;  2BHA A;  2EVC A;  5CE6 A;  2EA2 A;  1YW8 A;  1YJ3 A;  2GTX A;  3FM3 A;  1XGO A;  2GU4 A;  3MR1 A;  4U73 A;  2MAT A;  2Q96 A;  2Q8K A;  1C22 A;  1XGM A;  5FCF A;  1O0X A;  2BHD A;  4JUQ A;  2GG9 A;  4ZWO A;  2NQ6 A;  2OAZ A;  1WL9 A;  4RZY A;  3BIQ A;  4U71 A;  2GU7 A;  1WL6 A;  4A6W A; 
#chains in the Genus database with same CATH homology
 3PKD A;  1W2M A;  5CDV A;  2B3K A;  4RZZ A;  1QXY A;  1R5G A;  4U6J A;  2V3X A;  5CIK A;  4HXX A;  2GA2 A;  1B59 A;  2GGC A;  2EVO A;  4S2T P;  2Q93 A;  4U6W A;  2GG7 A;  1XGS A;  3TAV A;  2BWU A;  2GU5 A;  3Q6D A;  5JFR A;  1QXW A;  4IKU A;  1QXZ A;  2DFI A;  1XGN A;  5CNX A;  2P99 A;  1BOA A;  1QZY A;  4B28 A;  1N51 A;  2BWW A;  5D6E A;  2V6C A;  1C21 A;  5CDE A;  4U76 A;  1CHM A;  1C24 A;  3CB6 A;  4OOK A;  1WKM A;  1M35 A;  1XNZ A;  2B3L A;  2Q92 A;  3PKE A;  4QR8 A;  2OKN A;  3BIT A;  2BN7 A;  3TB5 A;  4IKR A;  1KQ0 A;  3RVA A;  3BIP A;  2BWV A;  4IEC A;  1Y1N A;  4IKS A;  1WBQ A;  4IPA A;  4RGZ 1;  5D6F A;  1WN1 A;  2GG2 A;  3S6B A;  2GG0 A;  4FLI A;  2BWX A;  3D27 A;  2P98 A;  2BWT A;  2G6P A;  2ADU A;  2Q95 A;  1WLR A;  4FLK A;  4U70 A;  3PKB A;  2EA4 A;  2BB7 A;  5CDL A;  3PKC A;  4S00 A;  2EVM A;  4IDY A;  1W7V A;  4FLL A;  4MAT A;  2GGB A;  2Q94 A;  4U6E A;  3IU8 A;  2BH3 A;  3MAT A;  4A6V A;  2GU6 A;  3IG4 A;  2V3Z A;  1C27 A;  5JI6 A;  1WY2 A;  1C23 A;  2GG8 A;  1YW9 A;  4PNC A;  4IF7 A;  1MAT A;  2HOW A;  2BWY A;  1R58 A;  1KP0 A;  4ZNG A;  4Z7M A;  4S2R P;  1KQ9 A;  1B6A A;  4FLJ A;  3L24 A;  4FKC A;  4S01 A;  2GG5 A;  2GZ5 A;  2ZSG A;  3PKA A;  4KM3 A;  1YVM A;  3CTZ A;  4EGE A;  4FO8 A;  5CLS A;  5E5B A;  1PV9 A;  4IKT A;  3IU7 A;  4U1B A;  4R60 A;  4ZWP A;  4FO7 A;  2BHB A;  2BWS A;  2GG3 A;  4PV4 A;  4FUK A;  2P9A A;  3ROR A;  1YW7 A;  2NQ7 A;  1A16 A;  2BHC A;  3FMR A;  4U75 A;  1BN5 A;  3L7G A;  4U6Z A;  2IW2 A;  2B3H A;  4IU6 A;  5JHU A;  3IU9 A;  1JAW A;  1R5H A;  3CB5 A;  5FCH A;  4U6C A;  2V3Y A;  3FMQ A;  3MX6 A;  4U69 A;  4ZWU A;  2BHA A;  2EVC A;  5CE6 A;  2EA2 A;  1YW8 A;  1YJ3 A;  2GTX A;  3FM3 A;  1XGO A;  2GU4 A;  3MR1 A;  4U73 A;  2MAT A;  2Q96 A;  2Q8K A;  1C22 A;  1XGM A;  5FCF A;  1O0X A;  2BHD A;  4JUQ A;  2GG9 A;  4ZWO A;  2NQ6 A;  2OAZ A;  1WL9 A;  4RZY A;  3BIQ A;  4U71 A;  2GU7 A;  1WL6 A;  4A6W A;
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similar chains in the Genus database (?% sequence similarity)
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similar chains in the pdb database (?% sequence similarity)

  
#similar chains in the Genus database (?% sequence similarity)
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#similar chains, but unknotted
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